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https://www.readbyqxmd.com/read/28764150/modulation-of-lung-function-by-increased-nitric-oxide-production
#1
Md Nazrul Islam, Ram Lochan Yadav, Prakash Kumar Yadav
INTRODUCTION: Cigarette smoking reduces endogenous Nitric Oxide (NO) production by reducing Nitric Oxide Synthase (NOS) activity, which is one of the probable reason for increased rate of pulmonary diseases in smokers. Nitric oxide/oxygen blends are used in critical care to promote capillary and pulmonary dilation to treat several pulmonary vascular diseases. Among several supplements, the highest NOS activation has been proved for garlic with its unique mechanism of action. AIM: To investigate the effect of dietary supplementation of NO producing garlic on pulmonary function of smokers...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28762366/prevalence-and-factors-associated-with-exercise-induced-bronchospasm-among-rural-school-children-in-ilesa-nigeria
#2
Bankole Peter Kuti, Demilade Kehinde Kuti, Kehinde Oluyori Omole, Lasisi Oluwafemi Mohammed, Busayo Gideon Ologun, Bolanle Idowu Oso
BACKGROUND: Exercise-induced bronchospasm (EIB) assessed using changes in peak expiratory flow rates (PEFRs) to free range exercise is a relatively cheap way of screening for asthma in resource-poor centres where children with asthma are often undiagnosed and poorly managed. This study sets out to determine the prevalence and factors associated with EIB among rural schoolchildren in Ilesa, Nigeria. SUBJECTS AND METHODS: Children aged 8-16 years from two middle schools in rural Ilesa were selected by multistage sampling...
April 2017: Nigerian Postgraduate Medical Journal
https://www.readbyqxmd.com/read/28702440/association-between-exercise-induced-asthma-and-parental-socio-economic-status-among-school-aged-adolescents-in-a-semiurban-community-in-nigeria
#3
Adekola A Adewumi, Rufus A Adedoyin, Taofeek O Awotidebe, Gregory E Erhabor, Olayemi F Awopeju, Rita N Ativie, Kayode I Oke
This study investigated the prevalence and association between exercise-induced asthma (EIA) and parental socio-economic status (PSES) among school-aged adolescents in a semiurban community in Nigeria. Three hundred and eighty-five adolescents (185 male and 200 female adolescents) whose ages ranged between 10 and 19 years participated in this cross-sectional study. Participants were recruited from four government approved secondary schools in Ido-Ekiti using a multistage sampling technique. Peak expiratory flow rate (PEFR) was assessed at baseline and after 6-min run test (6-MRT) on a level playing ground using a standard peak flow meter...
June 2017: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/28689213/respiratory-abnormalities-among-occupationally-exposed-non-smoking-brick-kiln-workers-from-punjab-india
#4
Supriya Tandon, Sharat Gupta, Sharanjeet Singh, Avnish Kumar
BACKGROUND: Brick manufacturing industry is one of the oldest and fast-growing industries in India that employs a large section of people. Brick kiln workers are occupationally exposed to air pollutants. Nonetheless, only a few studies have so far been conducted on their respiratory health. OBJECTIVE: To investigate the extent of respiratory impairment in brick kiln workers and to correlate it with the duration of exposure. METHODS: A cross-sectional study was conducted...
July 2017: International Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28671166/effects-of-oral-montelukast-on-airway-function-in-acute-asthma-a-randomized-trial
#5
Alisha Chaudhury, Gajanan S Gaude, Jyothi Hattiholi
BACKGROUND: The role of leukotriene receptor antagonist is well known in the management of chronic asthma, but their efficacy in acute exacerbation of asthma is unknown. The present study was done to evaluate the clinical efficacy of oral montelukast as an add on therapy to the usual standard therapy of acute attack of bronchial asthma. MATERIALS AND METHODS: A randomized single-blinded controlled study was conducted in a tertiary care teaching hospital. A total of 162 patients with age >18 years of acute exacerbations due to bronchial asthma were included in the study...
July 2017: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/28671152/effect-of-analgesia-on-the-changes-in-respiratory-parameters-in-blunt-chest-injury-with-multiple-rib-fractures
#6
Eyo Effiong Ekpe, Catherine Eyo
BACKGROUND: Blunt chest injury with multiple rib fractures can result in such complications as pneumonia, atelectasis, bronchiectasis, empyema thoracis, acute respiratory distress syndrome, and prolonged Intensive Care Unit and hospital stay, with its concomitant mortality. These may be prevented or reduced by good analgesic therapy which is the subject of this study. METHODS: This was a prospective study of effects of analgesia on changes in pulmonary functions of patients with traumatic multiple rib fractures resulting from blunt chest injury...
July 2017: Annals of African Medicine
https://www.readbyqxmd.com/read/28658755/occurrence-of-copd-in-patients-with-respiratory-allergy-a-clinico-spirometric-evaluation-in-a-tertiary-hospital-kolkata
#7
Sujoy Mukherjee, Goutam Banerjee, Debajyoti Das, Anil Baran Singha Mahapatra
INTRODUCTION: Smoking is established as the most important causative factor responsible for Chronic Obstructive Pulmonary Disease (COPD). Occurrence of allergy in COPD patients causes acute exacerbation of this disease, but role of allergy is not established in aetiopathogenesis of COPD. AIM: The present study was aimed at evaluation of occurrence of COPD in patients having symptoms suggestive of respiratory allergy. MATERIALS AND METHODS: An observational cross-sectional study was conducted to evaluate occurrence of COPD in patients having respiratory allergic symptoms by routine spirometric screening...
May 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28635359/thoracic-paravertebral-block-versus-intravenous-patient-controlled-analgesia-for-pain-treatment-in-patients-with-multiple-rib-fractures
#8
Ge Yeying, Yuan Liyong, Chen Yuebo, Zhang Yu, Ye Guangao, Ma Weihu, Zhao Liujun
Objectives To assess the effect of thoracic paravertebral block (PVB) on pain management and preservation of pulmonary function compared with intravenous, patient-controlled analgesia (IVPCA) in patients with multiple rib fractures (MRFs). Methods Ninety patients with unilateral MRFs were included in this prospective study and randomly assigned to the TPVB or IVPCA group. The visual analogue scale (VAS) pain score, blood gas analysis, and bedside spirometry were measured and recorded at different time points after analgesia...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28560545/relationships-among-peak-expiratory-flow-rate-body-composition-physical-function-and-sarcopenia-in-community-dwelling-older-adults
#9
Takeshi Kera, Hisashi Kawai, Hirohiko Hirano, Motonaga Kojima, Yoshinori Fujiwara, Kazushige Ihara, Shuichi Obuchi
BACKGROUND AND AIM: Although respiratory muscle strength is known to decrease with age, the relationship between pulmonary function and sarcopenia remains to be examined. The present study aimed to determine the relationship between peak expiratory flow rate (PEFR) and skeletal muscle mass/sarcopenia in community-dwelling older adults. METHODS: We utilized data from 427 older adults (age 74.4 ± 5.3 years, men/women 157/270) who had participated in the 2015 Otassha Kenshin, a longitudinal study that excluded participants with air-flow limitations...
May 30, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/28511377/an-analysis-of-dynamic-pulmonary-functions-of-hypothyroid-patients
#10
Seethalakshmi Krishna Iyer, Sunil K Menon, Biju Bahuleyan
INTRODUCTION: Hypothyroidism is a silent epidemic of our times. In India, the prevalence of hypothyroidism is 11%. The effect of hypothyroidism on respiratory system is debatable with studies suggesting both obstructive and restrictive disease patterns. The symptoms range from mild dyspnoea to life-threatening respiratory failure. This study emphasizes the effect of hypothyroidism on dynamic respiratory functions. AIM: To find out the changes in dynamic respiratory functions (FVC, FEV1, FEV1% and PEFR) in both male and female hypothyroid patients within age group of 18-45 years...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28491110/tai-chi-chuan-exercise-improves-pulmonary-function-and-decreases-exhaled-nitric-oxide-level-in-both-asthmatic-and-nonasthmatic-children-and-improves-quality-of-life-in-children-with-asthma
#11
Hsin-Chia Lin, Hao-Pai Lin, Hsin-Hui Yu, Li-Chieh Wang, Jyh-Hong Lee, Yu-Tsan Lin, Yao-Hsu Yang, Pei-Yi Li, Wei-Zen Sun, Bor-Luen Chiang
Tai-Chi-Chuan (TCC) is an exercise of low-to-moderate intensity which is suitable for asthmatic patients. The aim of our study is to investigate improvements of the lung function, airway inflammation, and quality of life of asthmatic children after TCC. Participants included sixty-one elementary school students and they were divided into asthmatic (n = 29) and nonasthmatic (n = 32) groups by the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire. Among them, 20 asthmatic and 18 nonasthmatic children volunteered to participate in a 60-minute TCC exercise weekly for 12 weeks...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28483184/electrodermal-screening-of-asthmatics-with-acugraph-4
#12
Kuntal Ghosh, Alex Hankey, Thaiyar M Srinivasan
Traditional Chinese Medicine holds that acupuncture meridian activity is correlated with quality of function of specific organs. This study sets out to determine acupuncture meridian characteristics of subjects with moderate asthma distinguishing them from healthy subjects. Fifty asthma patients (age 35.36 ± 8.68 years) and fifty similarly aged (34.11 ± 7.29 years) healthy volunteers were enrolled in the study. Electrodermal conductances at Jing Well points were measured with Acugraph 4 and also Peak Expiratory Flow Rate (PEFR) for the asthma group...
April 2017: Journal of Acupuncture and Meridian Studies
https://www.readbyqxmd.com/read/28459601/omalizumab-versus-mepolizumab-as-add-on-therapy-in-asthma-patients-not-well-controlled-on-at-least-an-inhaled-corticosteroid-a-network-meta-analysis
#13
Zahi Nachef, Amita Krishnan, Terry Mashtare, Tingting Zhuang, M Jeffery Mador
OBJECTIVE: The purpose of this study is to examine the comparative efficacy of Omalizumab (OMA) and Mepolizumab (Mepo) in the treatment of severe asthma by performing a network meta-analysis. METHOD: Data Sources: A systematic review of the literature was performed through four databases from their inception to February 2016. STUDY SELECTIONS: Randomized control trials and cohort studies were considered if they addressed the individual efficacy of OMA and Mepo in the treatment of asthma that was not well controlled on inhaled corticosteroids (ICSs) with or without other agents...
May 1, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28458532/relationship-between-lung-function-and-grip-strength-in-older-hospitalized-patients-a-pilot-study
#14
Sarah J Holmes, Stephen C Allen, Helen C Roberts
OBJECTIVE: Older people with reduced respiratory muscle strength may be misclassified as having COPD on the basis of spirometric results. We aimed to evaluate the relationship between lung function and grip strength in older hospitalized patients without known airways disease. METHODS: Patients in acute medical wards were recruited who were aged ≥70 years; no history, symptoms, or signs of respiratory disease; Mini Mental State Examination ≥24; willing and able to consent to participate; and able to perform hand grip and forced spirometry...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28389922/normal-peak-expiratory-flow-rate-of-school-children-in-jabalpur-madhya-pradesh
#15
Keerthi Kumaran, Avyact Agrawal
OBJECTIVES: To measure the Peak expiratory flow rate (PEFR) of healthy school children and to find out the correlation between PEFR values and anthropometric parameters, to create a nomogram of PEFR for children and formulate a regression formula for PEFR. METHODS: A cross-sectional study was conducted on healthy school children between the age group of 10 and 16 y, at three higher secondary schools selected in urban area of Jabalpur, Madhya Pradesh. After collecting baseline data, PEFR was measured using mini Wright peak flow meter...
August 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/28377880/paradoxical-bronchospasm-from-benzalkonium-chloride-bac-preservative-in-albuterol-nebulizer-solution-in-a-patient-with-acute-severe-asthma-a-case-report-and-literature-review-of-airway-effects-of-bac
#16
Mathew George, Saumya Vinod Joshi, Emily Concepcion, Haesoon Lee
Nebulized bronchodilator solutions are available in the United States as both nonsterile and sterile-filled products. Sulfites, benzalkonium chloride (BAC), or chlorobutanol are added to nonsterile products to prevent bacterial growth. Bronchoconstriction from inhaled BAC is cumulative, prolonged, and correlates directly with basal airway responsiveness. The multi-dose dropper bottle of albuterol sulfate solution contains 50 μg BAC per/2.5 mg of albuterol, which may be below or at the lower limit of the threshold dose for bronchoconstriction...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/28375782/the-potential-hazardous-effect-of-exposure-to-iron-dust-in-egyptian-smoking-and-nonsmoking-welders
#17
Naglaa Abd El Khalik Gobba, Abdelmaksoud Hussein Ali, Dalia E El Sharawy, Mohammed Abdalla Hussein
Exposure to iron dust and welding fumes is widespread and may increase the risk of lung inflammation. The aim of this study was to identify associations between exposure to iron/welding fumes and the levels of inflammatory parameters and allergic mediators among 120 Egyptian men. Forty nonsmoking and 40 smoking Egyptian welders as well as 40 healthy volunteers who were never exposed to welding fumes and were nonsmoking were enrolled in the study. Peak expiratory flow rates (PEFR) assessed at the end of the shift of work on working days revealed an impairment in lung function, with the smoking workers showing the worse results, followed by nonsmoking workers, as compared to healthy volunteers...
April 4, 2017: Archives of Environmental & Occupational Health
https://www.readbyqxmd.com/read/28360460/fractional-exhaled-nitric-oxide-is-a-useful-adjunctive-modality-for-monitoring-bronchial-asthma
#18
Venkatnarayan Kavitha, Anant Mohan, Karan Madan, Vijay Hadda, G C Khilnani, Randeep Guleria
BACKGROUND AND OBJECTIVE: To evaluate the utility of fractional exhaled nitric oxide (FeNO) in monitoring asthma control. MATERIALS AND METHODS: Steroid naïve nonsmoking asthmatics were recruited and followed for 6-8 weeks on standard treatment. Serial measurements of FeNO, peak expiratory flow rate (PEFR) variability, forced expiratory volume in 1 s (FEV1), bronchodilator reversibility (BDR), and asthma control test (ACT) score were measured at baseline and after 6-8 weeks of treatment...
March 2017: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/28360120/voluntary-upregulation-of-reflex-cough-is-possible-in-healthy-older-adults-and-parkinson-s-disease
#19
Alexandra E Brandimore, Karen W Hegland, Michael S Okun, Paul W Davenport, Michelle S Troche
Cough is an airway-protective mechanism that serves to detect and forcefully eject aspirate material. Existing research has identified the ability of healthy young adults to suppress or modify cough motor output based on external cueing. However, no study has evaluated the ability of people with Parkinson's disease (PD) and healthy older adults (HOAs) to upregulate cough motor output. The goal of this study was to evaluate the ability of people with PD and healthy age-matched controls (HOAs) to upregulate reflex and voluntary cough function volitionally with verbal instruction and visual biofeedback of airflow targets...
July 1, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28344949/the-effect-of-anesthesia-on-the-ventilatory-functions-of-patients-with-maxillo-mandibular-fixation
#20
B I Akhiwu, H O Akhiwu, B D Saheeb, M M Habeeb
BACKGROUND: Maxillo-mandibular fixation (MMF) is a procedure still routinely practiced in developing countries. AIM: To determine the variations in pulmonary functions readings between cases treated under general anesthesia (GA) and those treated under local anesthesia (LA). METHODOLOGY: A descriptive hospital-based study of 106 patients was carried out from January 2011- December 2012. Information was obtained using a questionnaire and all study subjects had their baseline lung functions and their post-operative daily lung function parameters measured for the first week and then weekly for the next five weeks...
April 2016: Journal of the West African College of Surgeons
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