keyword
https://read.qxmd.com/read/38492031/standard-medical-therapy-with-vs-without-nebulised-magnesium-for-children-with-asthma-decompensation
#1
JOURNAL ARTICLE
Luísa Cunha, Meritxell Roca Mora, Farhan Afzal, Giulia M Cesar, Catharina Ribeiro Guimarães, Julia Pereira Muniz Pontes, Gabriel Grando Alves, Antonio Carlos Fonseca Silveira
UNLABELLED: Pediatric asthma is a common condition, and its exacerbations can be associated with significant morbidity and mortality. The role of nebulised magnesium as adjunct therapy for children with asthma exacerbations is still unclear. To compare clinical and functional outcomes for children with asthma exacerbation taking either nebulised magnesium sulfate added to standard medical therapy (SMT) versus SMT alone. PubMed, Embase, and Cochrane Library were systematically searched for randomised clinical trials (RCT) comparing the use of SMT with vs...
March 16, 2024: European Journal of Pediatrics
https://read.qxmd.com/read/38479164/longitudinal-assessment-of-oxidative-stress-markers-and-their-relationship-with-exposure-to-pm-2-5-and-its-bound-metals-in-healthy-participants
#2
JOURNAL ARTICLE
Yuan-Ting Hsu, Ting-Yao Su, Trong-Neng Wu, Wei-Te Wu, Saou-Hsing Liou, Ching-Huang Lai, Shau-Ku Huang
OBJECTIVE: Exposure to ambient PM2.5 and its bound metals poses a risk to health and disease, via, in part, oxidative stress response. A variety of oxidative stress markers have been used as markers of response, but their relevance to environmental exposure remains to be established. We evaluated, longitudinally, a battery of oxidative stress markers and their relationship with the exposure of PM2.5 and its bound metals in a panel of healthy participants. MATERIAL AND METHODS: Levels of residence- and personal-based ambient air PM2...
March 12, 2024: International Journal of Hygiene and Environmental Health
https://read.qxmd.com/read/38470892/influence-of-acclimatization-time-on-parameters-of-barometric-whole-body-plethysmography-in-healthy-adult-cats
#3
JOURNAL ARTICLE
Petra Benz, Yury Zablotski, Bianka Schulz
BACKGROUND: Pulmonary function testing by barometric whole-body plethysmography (BWBP) is a long-established and well-accepted, non-invasive investigative procedure in cats. HYPOTHESIS/OBJECTIVES: To evaluate, if different acclimatization times influence the measurement parameters of BWBP in healthy adult cats. ANIMALS: 48 healthy adult cats. METHODS: In the prospective observational study, healthy cats were placed in a measuring chamber and BWBP was performed over 30 minutes...
2024: PloS One
https://read.qxmd.com/read/38467499/effect-of-the-modified-painless-blistering-moxibustion-with-wheat-grain-sized-moxa-cone-on-cough-variant-asthma-of-pathogenic-wind-attacking-the-lung-a-randomized-controlled-trial
#4
RANDOMIZED CONTROLLED TRIAL
Zhiyu Shao, Jinyi Guo, Xueqing Lu, Jun Cao, Yiwen Chen, Jing Li, Xiuzhen Su
OBJECTIVES: To observe the clinical effect of the modified painless blistering moxibustion with wheat-grain sized moxa cone on cough variant asthma (CVA) differentiated as pathogenic wind attacking the lung and explore the influences on eosinophil count (EOS) in the peripheral blood and the content of interleukin-4 (IL-4) and tumor necrosis factor-α (TNF-α) in the serum of patients. METHODS: Ninety-two patients with CVA of pathogenic wind attacking the lung were randomly divided into an observation group and a control group, 46 cases in each group...
March 12, 2024: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://read.qxmd.com/read/38430183/effect-of-wechat-based-medication-guidance-on-symptoms-and-serological-parameters-in-children-with-mycoplasma-pneumoniae
#5
JOURNAL ARTICLE
Ke Gao, Ke Zeng, Xiping Yu, Wu Zhao, Yanyan Qiu, Yuyang Li, Zhifei Li
OBJECTIVE: The aim of this study was to assess the effect of microsoft-based medication guidance on the level of symptoms and serological indicators in children receiving budesonide nebulisation combined with terbutaline for the treatment of Mycoplasma pneumoniae pneumoniae (MPP). METHODS: A total of 109 children with MPP treated in The First Affiliated Hospital of Ningbo University of China between October 2022 and April 2023 were divided into the conventional group (n=54, with medication guidance by telephone follow-up) and the WeChat group (n=55, with medication guidance based on the WeChat platform) using a randomized number table...
March 1, 2024: Alternative Therapies in Health and Medicine
https://read.qxmd.com/read/38428543/pulmonary-function-and-trajectories-of-cognitive-decline-in-aging-population
#6
JOURNAL ARTICLE
Albert J Ksinan, Andrea Dalecká, Tatyana Court, Hynek Pikhart, Martin Bobák
BACKGROUND: The number of older people with cognitive impairment is increasing worldwide. Impaired lung function might be associated with cognitive decline in older age; however, results from large longitudinal studies are lacking. In this study, we examined the longitudinal associations between pulmonary function and the trajectories of cognitive decline using prospective population-based SHARE data from 14 countries. METHODS: The analytic sample included N = 32,049 older adults (Mean age at baseline = 64...
February 28, 2024: Experimental Gerontology
https://read.qxmd.com/read/38418028/on-the-relation-between-tidal-and-forced-spirometry
#7
JOURNAL ARTICLE
Rutger H J Hebbink, Judith Elshof, Peter J Wijkstra, Marieke L Duiverman, Rob Hagmeijer
Spirometry is a lung function test involving deep inhalation and forceful deep exhalation. It is widely used to obtain objective information about airflow limitation and to diagnose lung diseases. In contrast, tidal spirometry is based on normal breathing and therefore much more convenient, but it is hardly used in medical care and its relation with conventional (forced) spirometry is largely unknown. Therefore, the objective of this work is to reveal the relation between tidal and forced spirometry. Employing the strong correspondence between the forced flow-volume curves and the Tiffeneau-Pinelli (TP) index, we present a method to obtain (a) the expected tidal flow-volume curve for a given TP-index, and (b) the expected TP-index for a given tidal curve...
February 2024: Medical Engineering & Physics
https://read.qxmd.com/read/38404770/effects-of-mixed-hardwoods-dust-on-respiratory-function-and-blood-immunoglobulin-levels-in-wood-workers
#8
JOURNAL ARTICLE
Isaac E Ennin, Festus K Adzaku, Daniel Dodoo, Raymond Saa-Eru Maalman
BACKGROUND: Occupational exposure to wood dust, generated by various individual wood species, both softwood and hardwood, has been extensively documented as a causative factor for reduced lung function, frequent respiratory symptoms, and increased immunological responses in wood workers. This study explores the impact of wood dust from mixed tropical hardwood species on lung function, respiratory symptoms, and Immunoglobulin (Ig) E and G levels. METHODS: A cross-sectional study was conducted among wood workers at the Accra Timber Market and a control group from the University of Ghana...
February 29, 2024: Heliyon
https://read.qxmd.com/read/38395640/intravenous-magnesium-sulfate-for-asthma-exacerbations-in-children-systematic-review-with-meta-analysis
#9
REVIEW
Dominika Ambrożej, Aleksander Adamiec, Erick Forno, Izabela Orzołek, Wojciech Feleszko, Jose A Castro-Rodriguez
BACKGROUND: Asthma is the most prevalent chronic disease in children and constitutes a significant healthcare burden. First-line therapy for acute asthma exacerbations is well established. However, secondary treatments, including intravenous magnesium sulfate (IV-MgSO4), remain variable due to scarcity of data on its efficacy and safety. OBJECTIVE: To assess the effectiveness and safety of IV-MgSO4 as a second line of treatment in managing children with asthma exacerbations...
February 12, 2024: Paediatric Respiratory Reviews
https://read.qxmd.com/read/38395458/association-between-pulmonary-function-and-rapid-kidney-function-decline-a-longitudinal-cohort-study-from-charls
#10
JOURNAL ARTICLE
Shisheng Han, Yanqiu Xu, Yi Wang
BACKGROUND: Pulmonary function has been reported to be associated with chronic kidney disease. However, the relationship between lung function and rapid kidney function decline remains unclear. METHODS: Participants aged ≥45 years with complete data from the 2011 and 2015 interviews of the China Health and Retirement Longitudinal Study (CHARLS) were included. Lung function, assessed by peak expiratory flow (PEF), and kidney function, assessed by estimated glomerular filtration rate (eGFR), were tested at the baseline and endpoint surveys...
February 23, 2024: BMJ Open Respiratory Research
https://read.qxmd.com/read/38385570/impact-of-the-pulmonary-ventilation-function-on-the-prognosis-of-suspected-asthma-patients-a-retrospective-observational-study
#11
JOURNAL ARTICLE
Ming-Juan Zhou, Li Fu, Wen-Qian Lin, Zhen-Ni Wu, Fang Nie, Chu-Yin Ye, Wen-Han Zhao
OBJECTIVE: Asthma is a common chronic respiratory diseases, and the relationship between pulmonary ventilation function and the prognosis of patients with suspected asthma is not well understood. This study aims to explore the impact of pulmonary ventilation functions on the prognosis of patients with suspected asthma. METHODS: This retrospective observational study included patients with suspected asthma who were diagnosed and treated at the Guangdong Provincial Hospital of Traditional Chinese Medicine between August 2015 and January 2020...
February 22, 2024: Journal of Asthma
https://read.qxmd.com/read/38364351/ayurveda-management-of-a-patient-having-bronchial-asthma-and-hemorrhoids-a-case-report
#12
JOURNAL ARTICLE
Punam Khobarkar, Amit Nakanekar
Ayurveda is a holistic science that treats root cause of diseases. One disease can become a causative factor for another disease. This concept is fundamentally described as Nidanarthakar Vyadhi in Ayurveda. In the same way, treating causative diseases is helpful in managing another diseases. However, many published clinical trials on Ayurveda management of Bronchial asthma and Hemorrhoids exist. There is a dearth of published case reports or clinical trials showing an association between Arsha (hemorrhoids) and Shwasa (bronchial asthma)...
February 15, 2024: Journal of Ayurveda and Integrative Medicine
https://read.qxmd.com/read/38337582/supplementary-respiratory-therapy-improves-pulmonary-function-in-pediatric-patients-with-cerebral-palsy-a-systematic-review-and-meta-analysis
#13
REVIEW
Erika Kolumbán, Márton Szabados, Márk Hernádfői, Uyen Nguyen Do To, Rita Nagy, Ádám Zolcsák, Katalin Eszter Müller, Zoltán Sipos, Dániel Sándor Veres, Anett Szőllősi, Péter Hegyi, Miklós Garami, Ibolya Túri
BACKGROUND: Despite medical advances, individuals with cerebral palsy (CP) face significant respiratory challenges, leading to heightened hospitalization rates and early mortality among this population. We hypothesize that integrating supplementary respiratory therapy into standard rehabilitation will result in significant improvements in pulmonary function, enhanced respiratory muscle strength, and an overall increase in the quality of life among pediatric patients with CP. METHODS: A systematic search of literature across five databases was conducted, and random-effects meta-analyses were performed to assess the impact of supplementary respiratory therapy on (a) pulmonary function: forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1), FVC/FEV1 ratio, peak expiratory flow (PEF), and (b) respiratory muscle strength: maximal inspiratory and expiratory pressure (MIP, MEP), and (c) quality of life...
February 2, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38336766/the-impact-of-strategic-napping-on-peak-expiratory-flow-and-respiratory-function-in-young-elite-athletes
#14
JOURNAL ARTICLE
Ahmet Kurtoğlu, Özgür Eken, Engin Aydın, Bekir Çar, Hadi Nobari
Respiratory health is a critical determinant of athletic performance, and the utilization of restorative strategies, such as strategic napping, may offer a competitive edge to athletes. This study investigates the effects of nap duration on the respiratory function of young elite athletes who have achieved top rankings national competitions. Participants engage in three test sessions with varying nap durations: no nap (N0), a 25-minute nap (N25), and a 45-minute nap (N45), with a minimum 72-hour interval between sessions...
February 9, 2024: BMC Sports Science, Medicine and Rehabilitation
https://read.qxmd.com/read/38336616/effects-of-pressure-controlled-ventilation-targeting-end-inspiratory-flow-rate-on-pulmonary-complications-and-inflammation-levels-in-patients-undergoing-spinal-surgery-in-the-prone-position-a-randomized-clinical-trial
#15
RANDOMIZED CONTROLLED TRIAL
Na Wang, Yong Ye, Hui Lin, Tingting Sun, Yue Hu, Yuanhang Shu, Jing Tong, Yong Tao, Zeyu Zhao
BACKGROUND: This study assessed the impact of pressure-controlled ventilation (PCV) focusing on end-inspiratory flow rate on the incidence of postoperative pulmonary complications (PPCs) and inflammation levels in patients undergoing spinal surgery in the prone position. METHODS: A total of 187 patients who underwent posterior spinal surgery were enrolled and randomly divided into 3 groups: 61 in the volume-controlled ventilation (VCV) group (group V), 62 in the PCV-volume-guaranteed (VG) group (group P1 ), and 64 in the PCV-VG end-expiratory zero flow rate group (group P2 )...
February 9, 2024: BMC Anesthesiology
https://read.qxmd.com/read/38322555/prognosis-of-infants-with-congenital-pulmonary-airway-malformations-after-surgery-a-short-and-mid-term-evaluation
#16
JOURNAL ARTICLE
Jiachi Liao, Minhua Lin, Jiahang Zeng, Fenghua Wang, Jue Tang, Qinglin Yang, Dongmei Huang, Zefeng Lin, Jianhua Liang, Le Li
OBJECTIVE: To investigate the postoperative pulmonary function, imaging descriptions and complications in infants with congenital pulmonary airway malformations (CPAM), and to examine the impact of different surgical resections on the prognosis of infants. METHODS: Data of 30 infants with CPAM who underwent surgery at the department of Pediatric Surgery, Guangzhou Women and Children's Medical Center from June 2021 to June 2022 were retrospectively collected and analyzed...
2024: American Journal of Translational Research
https://read.qxmd.com/read/38318072/suppressing-inflammatory-signals-and-apoptosis-linked-sphingolipid-metabolism-underlies-therapeutic-potential-of-qing-jin-hua-tan-decoction-against-chronic-obstructive-pulmonary-disease
#17
JOURNAL ARTICLE
Jing Yang, Xin Shen, Mi Qin, Ping Zhou, Fei-Hong Huang, Yun You, Long Wang, Jian-Ming Wu
BACKGROUND: Qing-Jin-Hua-Tan decoction (QJHTD) is a classic traditional Chinese medicine (TCM) prescription that first appeared in the ancient book Yi-Xue-Tong-Zhi. QJHTD has shown effectiveness for treating chronic obstructive pulmonary disease (COPD), although its mechanisms of action are still perplexing. The molecular mechanisms underlying the curative effects of QJHTD on COPD is worth exploring. METHODS: In vitro antiapoptotic and antiinflammatory activities of QJHTD were evaluated using cell viability, proliferation, apoptosis rate, and expression of IL-1β and TNF-α in BEAS-2B and RAW264...
February 15, 2024: Heliyon
https://read.qxmd.com/read/38309959/-standard-technical-specifications-for-methacholine-chloride-methacholine-bronchial-challenge-test-2023
#18
JOURNAL ARTICLE
(no author information available yet)
The methacholine challenge test (MCT) is a standard evaluation method of assessing airway hyperresponsiveness (AHR) and its severity, and has significant clinical value in the diagnosis and treatment of bronchial asthma. A consensus working group consisting of experts from the Pulmonary Function and Clinical Respiratory Physiology Committee of the Chinese Association of Chest Physicians, the Task Force for Pulmonary Function of the Chinese Thoracic Society, and the Pulmonary Function Group of Respiratory Branch of the Chinese Geriatric Society jointly developed this consensus...
February 12, 2024: Chinese Journal of Tuberculosis and Respiratory Diseases
https://read.qxmd.com/read/38307568/prognostic-impact-of-preoperative-assessment-of-muscle-mass-and-strength-in-surgically-resected-lung-cancer
#19
JOURNAL ARTICLE
Shusuke Kurihara, Ryota Nakamura, Satoshi Yoneyama, Shiho Takase, Takashi Hatori, Tetsuya Yamagishi, Takeshi Numata, Kyoko Ota, Hidetoshi Yanai, Takeo Endo, Yukinori Inadome, Hiroaki Satoh, Ryo Muto, Kiyoshi Fukunaga
BACKGROUND/AIM: The association between resected non-small cell lung cancer (NSCLC) and long-term outcomes of muscle mass depletion and muscle weakness has also not been well documented. This study evaluated whether muscle mass depletion assessed by bioelectrical impedance analysis (BIA) and low muscle strength assessed by the peak expiratory flow rate as a percentage of predicted value (%PEFR) were associated with surgical outcomes in patients with resected NSCLC. PATIENTS AND METHODS: This retrospective study included 219 patients with resected NSCLC between 2016 and 2021...
February 2024: Anticancer Research
https://read.qxmd.com/read/38294702/efficacy-of-bronchial-thermoplasty-in-a-patient-panel-with-uncontrolled-severe-persistent-asthma
#20
JOURNAL ARTICLE
Antonios Zikos, Marvin Balaan, Emily Hobart, Sandeep Bansal, Rihab Saeed, Tariq Cheema, Deborah Gentile
BACKGROUND: Bronchial thermoplasty (BT) is an approved procedure to manage uncontrolled severe persistent asthma. Many insurance providers are reluctant to pay for BT without proven benefit among their specific patient panel. OBJECTIVE: Determine if BT is effective in a panel patient panel with uncontrolled severe persistent asthma. STUDY DESIGN AND METHODS: This was an unblinded prospective study of adult subjects with uncontrolled severe persistent asthma who underwent BT...
January 31, 2024: Journal of Asthma
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