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https://www.readbyqxmd.com/read/28301050/addition-of-anti-leukotriene-agents-to-inhaled-corticosteroids-for-adults-and-adolescents-with-persistent-asthma
#1
REVIEW
Bhupendrasinh F Chauhan, Maya M Jeyaraman, Amrinder Singh Mann, Justin Lys, Ahmed M Abou-Setta, Ryan Zarychanski, Francine M Ducharme
BACKGROUND: Asthma management guidelines recommend low-dose inhaled corticosteroids (ICS) as first-line therapy for adults and adolescents with persistent asthma. The addition of anti-leukotriene agents to ICS offers a therapeutic option in cases of suboptimal control with daily ICS. OBJECTIVES: To assess the efficacy and safety of anti-leukotriene agents added to ICS compared with the same dose, an increased dose or a tapering dose of ICS (in both arms) for adults and adolescents 12 years of age and older with persistent asthma...
March 16, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28264672/reference-equations-for-spirometric-indices-from-a-sample-of-the-general-adult-population-in-nigeria
#2
Ademola Emmanuel Fawibe, Louis O Odeigah, Mohammed J Saka
BACKGROUND: The increasing importance of pulmonary function testing in diagnosing and managing lung diseases and assessing improvement has necessitated the need for locally derived reference equations from a sample of the general Nigerian population. METHODS: It was a cross sectional study in which we used linear regression models to obtain equations for reference values and lower limits of normal for spirometric indices in adult Nigerians from a sample of the general population aged 18-65 years (males) and 18-63 years (females)...
March 6, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/28250927/technical-and-clinical-validation-of-the-allergen-biocube-%C3%A2-for-timothy-grass
#3
Endri Angjeli, Paul Gomes, Keith J Lane, Linda Stein, Mark B Abelson
INTRODUCTION: Field studies for allergic rhinitis (AR) commonly have inconsistent allergen concentrations and subject exposure patterns due to varying environmental conditions and subject behaviors. A technical and clinical validation study was conducted for the Allergen BioCube(®) using timothy grass to confirm uniform allergen concentration and clinically relevant subject symptom responses. METHODS: Allergen concentrations were verified by laser particle counts...
March 2017: Immunity, Inflammation and Disease
https://www.readbyqxmd.com/read/28208847/effect-of-different-phases-of-menstrual-cycle-on-cardio-respiratory-efficiency-in-normal-overweight-and-obese-female-undergraduate-students
#4
Nazrin Samsudeen, Archana Rajagopalan
INTRODUCTION: The influence of obesity on cardio-respiratory efficiency in the various phases of menstrual cycle is not well understood until now. As majority of Indian women have a favourable attitude towards participation in sports it is significant to understand the variation in exercise performance during different phases of menstrual cycle to have an optimum performance. AIM: To evaluate the endurance capacity and cardio-respiratory responses in normal, obese and overweight female undergraduate students during different phases of menstrual cycle...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28194084/civil-construction-work-the-unseen-contributor-to-the-occupational-and-global-disease-burden
#5
R Sitalakshmi, P Saikumar, P Jeyachandran, Manoharan, Thangavel, Jayakar Thomas
BACKGROUND: Construction industry is the second largest employment giving industry in India with many semi-skilled or unskilled workers taking up the occupation for livelihood without any training and proper guidance. AIM: To evaluate the pathogenic association of cement exposure to occupational contact dermatoses as evidenced by immune markers and to correlate their pulmonary functions with years of exposure to cement. SETTING AND DESIGN: This was a cross-sectional study conducted among randomly selected cement workers...
May 2016: Indian Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28191318/structured-pharmaceutical-care-improves-the-health-related-quality-of-life-of-patients-with-asthma
#6
Philip O Anum, Berko P Anto, Audrey G Forson
BACKGROUND: Asthma as a chronic health condition can be controlled when in addition to clinical care, adequate education and support is provided to enhance self-management. Like many other chronic health conditions improved self-management positively impacts the health-related quality of life (HRQoL). It can therefore be said that a well-structured pharmaceutical care delivery that addresses the issues related to patient education and support towards self-management stands a good chance of positively impacting asthma control...
2017: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/28160155/age-specific-peak-expiratory-flow-nomogram-in-children
#7
Mahfooz Ahmed, Jeetendra Gavhane, Sorabh Goel
OBJECTIVE: To determine peak flow rate nomogram in children between 5 to 12 y of age in suburban population. METHODS: This was a cross-sectional study randomly done on 5000 healthy school children. Mini-Wright flow meter was used for measurement of peak expiratory flow rate (PEFR). The range of age, weight and height were defined and linear and multiple regression analysis were performed. RESULTS: Correlation between PEFR and height was more significant and between PEFR and weight was lower...
February 4, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/28160097/indoor-environmental-factors-associated-with-pulmonary-function-among-adults-in-an-acid-rain-plagued-city-in-southwest-china
#8
Jie Yu, Longju Zhang, Ya Luo, Yin Tang, Fangxu Tuo, Jiaqi Yang, Jie Xu
OBJECTIVE: To assess the association of indoor environmental risk factors with respiratory function among adults in an acid rain-plagued city in China where coal use is frequent. METHODS: The subjects were randomly selected in the winter season. Information on selected home environmental factors was collected through administered questionnaires. Additionally, pulmonary function tests, including Forced Vital Capacity (FVC), Forced Expiratory Volume in 1 s (FEV1), FEV1/FVC and Peak Expiratory Flow Rate (PEFR) were also performed in participants...
February 3, 2017: Wiener Klinische Wochenschrift
https://www.readbyqxmd.com/read/28057838/temporal-evolution-of-thoracocentesis-induced-changes-in-spirometry-and-respiratory-muscle-pressures
#9
Stylianos A Michaelides, George D Bablekos, Antonis Analitis, George Ionas, Petros Bakakos, Konstantinos A Charalabopoulos
BACKGROUND: Several studies investigated the effects of thoracocentesis on aspects of respiratory function without generally ensuring absence of coexistent lung pathology or homogeneity in initial size of the effusion. METHODS: We studied 90 patients aged 61.6±15.9 years (mean±SD) separated into a group A with small-sized or medium-sized effusion (A=56 patients) and a group B with large and massive one (B=34 patients). There was no significant lung lesion or cardiovascular pathology...
January 5, 2017: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/28032061/indoor-environmental-factors-and-occurrence-of-lung-function-decline-in-adult-residents-in-summer-in-southwest-china
#10
Yu Jie, Li Kebin, Tang Yin, Xu Jie
BACKGROUND: There is conflicting reports on the respiratory health effects of indoor risk factor exposure. The aim of this study was to assess the association of indoor environmental factors to pulmonary function in an adult population in Zunyi City of Southwest China. METHODS: Between July and Sep 2012, we conducted a cross-sectional survey of people aged ≥18 yr in 11 inner-city areas of Zunyi. Data on asthma and asthma-related symptoms and selected home environmental factors were assessed by questionnaire...
November 2016: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/27976662/respiratory-function-in-vocal-soloists-opera-singers-and-wind-instrument-musicians
#11
Helen Ksinopoulou, Chryssa Hatzoglou, Zoe Daniil, Konstantinos Gourgoulianis, Helen Karetsi
INTRODUCTION: Current studies have not yet reached a definitive conclusion on the effects of singing and playing wind instruments professionally on an individual's respiratory function. OBJECTIVE: The purpose of this study was to investigate the respiratory function of wind instrument players and opera singers in comparison with a group of healthy individuals. METHODS: The experimental group comprised 45 men and 35 women, 58 opera singers and vocal soloists in total and 22 wind instruments players...
December 13, 2016: La Medicina del Lavoro
https://www.readbyqxmd.com/read/27941715/peak-expiratory-flow-rate-pefr-in-first-and-third-trimester-of-pregnancy
#12
M R Zannat, A Nessa
In this cross sectional study peak expiratory flow rate (PEFR) were estimated in pregnant women during the first trimester of pregnancy and in third trimester of pregnancy, to observe the alteration in airflow rate during pregnancy. This cross sectional study carried out in the Department of Physiology of Mymensingh Medical College, Mymensingh, Bangladesh from July 2014 to June 2015. For this purpose, total 300 women with age ranged from 18 to 35 years without any recent history of respiratory diseases were selected and divided into 100 healthy non pregnant women as control group and 200 normal pregnant women as study group...
October 2016: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/27894507/do-simple-beside-lung-function-tests-predict-morbidity-after-rib-fractures
#13
Christopher A Butts, John J Brady, Sara Wilhelm, Laura Castor, Alicia Sherwood, Abby McCall, John Patch, Pamela Jones, Vicente Cortes, Adrian W Ong
BACKGROUND: We evaluated if incentive spirometry volume (ISV) and peak expiratory flow rate (PEFR) could predict acute respiratory failure (ARF) in patients with rib fractures. METHODS: Normotensive, co-operative patients were enrolled prospectively. ISV and PEFR were measured on admission, at 24 h and at 48 h by taking the best of three readings each time. The primary outcome, ARF, was defined as requiring invasive or noninvasive positive pressure ventilation...
November 19, 2016: American Journal of Surgery
https://www.readbyqxmd.com/read/27888045/effects-of-tiotropium-on-lung-function-in-current-smokers-and-never-smokers-with-bronchial-asthma
#14
Makoto Yoshida, Yasuko Kaneko, Akiko Ishimatsu, Masashi Komori, Tomoaki Iwanaga, Hiromasa Inoue
The effects of tiotropium, an inhaled long-acting muscarinic antagonist, on lung function were investigated in current smokers and nonsmokers with asthma treated with inhaled corticosteroids (ICSs) and other asthma controllers: inhaled long-acting β2 agonists, leukotriene receptor antagonists, and/or theophylline. We conducted a double-blind, placebo-controlled study of an inhaled single dose of tiotropium in 9 asthmatics currently smoking and 9 asthmatics who have never smoked in a crossover manner. Lung function was measured before and 1, 3, and 24 h after inhalation of 18 μg of tiotropium or a placebo...
February 2017: Pulmonary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/27865240/prediction-equations-for-spirometry-in-adults-in-western-india
#15
Unnati Desai, Jyotsna M Joshi, S K Chhabra, Mujeeb-Ur Rahman
BACKGROUND: Spirometry is an essential investigation in pulmonology. The predicted normal spirometry values depend on various physiological parameters. This study was conducted to collect updated information on pulmonary functions in normal adults from western India. MATERIAL AND METHODS: A prospective observational study was undertaken at a tertiary hospital in Mumbai enrolling healthy subjects, 18-75 years, with ethnic origin from western India. Spirometry measurements were carried out as per ATS/ERS-2005 guidelines using a non-heated Fleish Pneumotachograph spirometer...
July 2016: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/27853055/health-status-assessment-of-workers-during-construction-phase-of-highway-rehabilitation-projects-around-lahore-pakistan
#16
Amina Abrar, Kausar Jamal Cheema, Samia Saif, Asim Mahmood
OBJECTIVE: The study focused on assessment of the health status of workers during construction phase of highway rehabilitation projects at six selected sites of N5 around Lahore, including Kala Shah Kaku, Muridke, Kamuki, Bhaipheru, Pattoki, and Okara. METHODS: The study was based on multi-methods approach involving hazard identification through survey and checklist as well as a questionnaire for health status assessment and measurements of health parameters including peak expiratory flow rate (PEFR) and audiometric screening of 300 subjects...
November 16, 2016: Journal of Occupational Health
https://www.readbyqxmd.com/read/27834336/evaluation-of-symptoms-spirometry-in-children-treated-for-asthma
#17
Shobi Anandi, Milind S Tullu, Keya Lahiri
BACKGROUND & OBJECTIVES: Spirometry plays an important role in the assessment and long term monitoring of patients with asthma. Difficulty in performing spirometry in children has resulted in a paucity of Indian studies using spirometry regularly for research in the paediatric population. This study was undertaken to assess the clinical improvement and changes in spirometric measurements with treatment in children with newly diagnosed asthma and to compare the changes in the symptom score and spirometric measurements...
July 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27790554/comparison-between-thoracic-epidural-block-and-thoracic-paravertebral-block-for-post-thoracotomy-pain-relief
#18
Soniya Biswas, Reetu Verma, Vinod Kumar Bhatia, Ajay Kumar Chaudhary, Girish Chandra, Ravi Prakash
INTRODUCTION: Postoperative pain after thoracotomy is being considered one of the most severe pain and if not treated well, can result in various respiratory and other complications. AIM: Present study was conducted with the aim to compare continuous thoracic epidural infusion with continuous paravertebral infusion for postoperative pain using Visual Analogue Scale (VAS) score and four point observer ranking. The secondary outcomes measured were pulmonary functions and any complication like hypotension, bradycardia, nausea, vomiting, urinary retention and neurological complications if any...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27771645/prediction-equations-for-spirometry-for-children-from-northern-india
#19
Sunil K Chhabra, Rajeev Kumar, Vikas Mittal
OBJECTIVE: To develop prediction equations for spirometry for children from northern India using current international guidelines for standardization. DESIGN: Re-analysis of cross-sectional data from a single school. PARTICIPANTS: 670 normal children (age 6-17 y; 365 boys) of northern Indian parentage. METHODS: After screening for normal health, we carried out spirometry with recommended quality assurance according to current guidelines...
September 8, 2016: Indian Pediatrics
https://www.readbyqxmd.com/read/27721534/a-prospective-randomized-study-evaluation-of-the-effect-of-rosuvastatin-in-patients-with-chronic-obstructive-pulmonary-disease-and-pulmonary-hypertension
#20
Bharti Chogtu, Sanitha Kuriachan, Rahul Magazine, K Ranjan Shetty, Asha Kamath, Manu Mathew George, Amruta Tripathy, D Mahesh Kumar
OBJECTIVES: Statins by their anti-inflammatory and endothelial stabilizing effect can be beneficial in patients with chronic obstructive pulmonary disease (COPD) and pulmonary hypertension (PH). The present study was done to evaluate the effect of rosuvastatin on pulmonary functions and quality of life (QOL) in patients with concomitant COPD and PH. MATERIALS AND METHODS: It was a prospective, randomized, double-blind, placebo-controlled, study conducted in patients with COPD and PH...
September 2016: Indian Journal of Pharmacology
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