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https://www.readbyqxmd.com/read/28536203/reply-to-bridgewater-and-babin-need-for-a-new-protected-area-category-for-ecosystem-services
#1
Weihua Xu, Yi Xiao, Jingjing Zhang, Wu Yang, Lu Zhang, Vanessa Hull, Zhi Wang, Hua Zheng, Jianguo Liu, Stephen Polasky, Ling Jiang, Yang Xiao, Xuewei Shi, Enming Rao, Fei Lu, Xiaoke Wang, Gretchen C Daily, Zhiyun Ouyang
No abstract text is available yet for this article.
May 23, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28533976/phylogenetic-climatic-niche-conservatism-and-evolution-of-climatic-suitability-in-neotropical-angraecinae-vandeae-orchidaceae-and-their-closest-african-relatives
#2
Marta Kolanowska, Elżbieta Grochocka, Kamil Konowalik
In the present study we investigate the concept of phylogenetic niche conservatism (PNC) within the American species of angraecoid orchids (Campylocentrum and Dendrophylax) and their closest relatives in the Old World (Angraecum) using ecological niche modelling (ENM). The predicted niche occupancy profiles were matched with the outcomes of previous phylogenetic studies to reconstruct the evolution of climatic suitability within the orchid group studied and evaluate the role of niche differentiation in the speciation of Angraecinae...
2017: PeerJ
https://www.readbyqxmd.com/read/28529146/multiple-endpoints-to-evaluate-pristine-and-remediated-titanium-dioxide-nanoparticles-genotoxicity-in-lung-epithelial-a549-cells
#3
Andrea Stoccoro, Sebastiano Di Bucchianico, Fabio Coppedè, Jessica Ponti, Chiara Uboldi, Magda Blosi, Camilla Delpivo, Simona Ortelli, Anna Luisa Costa, Lucia Migliore
Titanium dioxide nanoparticles (TiO2 NP) are broadly used in a wide range of applications. Several studies have reported that TiO2 NP possess cytotoxic and genotoxic properties that could induce adverse health effects in humans. The FP7 Sanowork project was aimed to minimize occupational hazard and exposure to engineered nanomaterials (ENM), including TiO2 NP, through the surface modification in order to avoid possible adverse toxic effects for humans. In this study we investigated cytotoxicity, genotoxicity and epigenetic properties of TiO2 NP uncoated and coated with silica or citrate, as well as of the benchmark material P25...
May 18, 2017: Toxicology Letters
https://www.readbyqxmd.com/read/28524743/nanoparticle-exposures-from-nano-enabled-toner-based-printing-equipment-and-human-health-state-of-science-and-future-research-needs
#4
Sandra Vanessa Pirela, John Martin, Dhimiter Bello, Philip Demokritou
Toner formulations used by laser printers (LP) and photocopiers (PC), collectively called "toner-based printing equipment" (TPE), are nano-enabled products (NEP) because they contain several engineered nanomaterials (ENM) that improve toner performance. It has been shown that during consumer use (printing), these ENM are released in the air, together with other semi-volatile organic nanoparticles, and newly formed gaseous co-pollutants such as volatile organic compounds (VOC). The aim of this review is to detail and analyze physico-chemical and morphological (PCM), as well as the toxicological properties of particulate matter (PM) emissions from TPE...
May 19, 2017: Critical Reviews in Toxicology
https://www.readbyqxmd.com/read/28524186/taurine-modified-ru-ii-complex-targets-cancerous-brain-cells-for-photodynamic-therapy
#5
Enming Du, Xunwu Hu, Sona Roy, Peng Wang, Kieran Deasy, Toshiaki Mochizuki, Ye Zhang
The precision and efficacy of photodynamic therapy (PDT) is essential for the treatment of brain tumors because the cancer cells are within or adjacent to the delicate nervous system. Taurine is an abundant amino acid in the brain that serves the central nervous system (CNS). A taurine-modified polypyridyl Ru-complex was shown to have optimized intracellular affinity in cancer cells through accumulation in lysosomes. Symmetrical modification of this Ru-complex by multiple taurine molecules enhanced the efficiency of molecular emission with boosted generation of reactive oxygen species...
May 19, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28524032/-preoperative-risk-factors-analysis-of-pulmonary-hypertension-crisis-during-perioperative-period-for-caesarean-section-of-woman-with-severe-pulmonary-hypertension
#6
Chunlei Zhang, Yaguang Liu, Enming Qing, Jun Ma
OBJECTIVE: To analyze preoperative risk factors of perioperative pulmonary hypertension crisis (PHC) for pregnant woman with severe pulmonary artery hypertension (PAH), and approach its clinical value. METHODS: A retrospective analysis was conducted. The clinical data from 152 pregnant women with severe PAH underwent cesarean delivery admitted to Beijing Anzhen Hospital from January 1st 2008 to December 31st 2016 was collected. The patients were divided into two groups according to with perioperative PHC or not...
May 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28515660/environmental-factors-associated-with-the-distribution-of-visceral-leishmaniasis-in-endemic-areas-of-bangladesh-modeling-the-ecological-niche
#7
Abu Yousuf Md Abdullah, Ashraf Dewan, Md Rakibul Islam Shogib, Md Masudur Rahman, Md Faruk Hossain
BACKGROUND: Visceral leishmaniasis (VL) is a parasitic infection (also called kala-azar in South Asia) caused by Leishmania donovani that is a considerable threat to public health in the Indian subcontinent, including densely populated Bangladesh. The disease seriously affects the poorest subset of the population in the subcontinent. Despite the fact that the incidence of VL results in significant morbidity and mortality, its environmental determinants are relatively poorly understood, especially in Bangladesh...
2017: Tropical Medicine and Health
https://www.readbyqxmd.com/read/28515184/trends-and-population-attributable-risk-estimates-for-predictors-of-early-neonatal-mortality-in-nigeria-2003-2013-a-cross-sectional-analysis
#8
Osita Kingsley Ezeh
OBJECTIVES: To assess trends in early neonatal mortality (ENM) and population-attributable risk (PAR) estimates for predictors of ENM in Nigeria. DESIGN, SETTING AND PARTICIPANTS: A cross-sectional data on 63 844 singleton live births within the preceding 5 years from the 2003, 2008 and 2013 Nigeria Demographic and Health Surveys were used. Adjusted PARs were used to estimate the number of early neonatal deaths attributable to each predictor in the final multivariable Cox regression model...
May 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28490217/antimicrobial-proteins-in-the-response-to-graphene-oxide-in-caenorhabditis-elegans
#9
Mingxia Ren, Li Zhao, Xiao Lv, Dayong Wang
Upon exposure to environmental engineered nanomaterials (ENMs), animals will activate certain response signals to protect themselves from the toxic effects. However, the underlying molecular mechanisms for this response are still largely unclear. Using in vivo assay system of Caenorhabditis elegans, we here found that antimicrobial proteins of LYS-1, LYS-8, SPP-1, DOD-6, and F55G11.4 were activated by graphene oxide (GO) exposure. These antimicrobial proteins functioned as molecular targets of transcriptional factor DAF-16 in insulin signaling pathway, and acted in intestine to regulate the response to GO...
May 10, 2017: Nanotoxicology
https://www.readbyqxmd.com/read/28489472/enalapril-maleate-orally-disintegrating-tablets-tableting-and-in-vivo-evaluation-in-hypertensive-rats
#10
Hesham M Tawfeek, Waleed Faisal, Ghareb M Soliman
The aim of this study was to develop orally disintegrating tablets (ODTs) for enalapril maleate (EnM) to facilitate its administration to the elderly or other patients having dysphagia. Compatibility between EnM and various excipients was studied using differential scanning calorimetry. ODTs of EnM were prepared by direct compression of EnM mixtures with various superdisintegrants. The tablets were evaluated for physical properties including drug content, hardness, friability, disintegration time, wetting time and drug release...
May 10, 2017: Pharmaceutical Development and Technology
https://www.readbyqxmd.com/read/28487259/the-role-of-niche-divergence-and-geographic-arrangement-in-the-speciation-of-eared-pheasants-crossoptilon-hodgson-1938
#11
Pengcheng Wang, Yang Liu, Yinong Liu, Yajing Chang, Nan Wang, Zhengwang Zhang
One of the most contentious theories in current ecology is the ecological niche conservatism, which is defined as conservatism among closely related species; however, the ecological niche can also be shifted, as documented in several cases. Genetic drift and ecological divergent selection may cause ecological niche divergence. The current study aims to test whether the ecological niche is conserved or divergent and to determine the main factor that drives ecological niche divergence or conservation. We analyzed the phylogenetic relationship, ecological niche model (ENM) and demographic history of Eared Pheasants in the genus Crossoptilon (Galliformes: Phasianidae) to test niche conservatism with respect to different geographically distributed patterns...
May 6, 2017: Molecular Phylogenetics and Evolution
https://www.readbyqxmd.com/read/28480337/structure-activity-relationships-of-engineered-nanomaterials-in-inducing-nlrp3-inflammasome-activation-and-chronic-lung-fibrosis
#12
Xiang Wang, Bingbing Sun, Sijin Liu, Tian Xia
It has been demonstrated that certain engineered nanomaterials (ENMs) could induce chronic lung inflammation and fibrosis, however, the key structure activity relationships (SARs) that the link the physicochemical properties and the fibrogenic effects have not been thoroughly reviewed. Recently, significant progress has been made in our understanding of the SAR, and it has been demonstrated that ENMs including rare earth oxides (REOs), graphene and graphene oxides (GO), fumed silica, as well as high aspect ratio materials (such as CNTs and CeO2 nanowires etc...
April 2017: NanoImpact
https://www.readbyqxmd.com/read/28472330/dynomics-dynamics-of-structural-proteome-and-beyond
#13
Hongchun Li, Yuan-Yu Chang, Ji Young Lee, Ivet Bahar, Lee-Wei Yang
DynOmics (dynomics.pitt.edu) is a portal developed to leverage rapidly growing structural proteomics data by efficiently and accurately evaluating the dynamics of structurally resolved systems, from individual molecules to large complexes and assemblies, in the context of their physiological environment. At the core of the portal is a newly developed server, ENM 1.0, which permits users to efficiently generate information on the collective dynamics of any structure in PDB format, user-uploaded or database-retrieved...
May 3, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28470912/jumping-between-protein-conformers-using-normal-modes
#14
Swapnil Mahajan, Yves-Henri Sanejouand
The relationship between the normal modes of a protein and its functional conformational change has been studied for decades. However, using this relationship in a predictive context remains a challenge. In this work, we demonstrate that, starting from a given protein conformer, it is possible to generate in a single step model conformers that are less than 1 Å (Cα -RMSD) from the conformer which is the known endpoint of the conformational change, particularly when the conformational change is collective in nature...
May 3, 2017: Journal of Computational Chemistry
https://www.readbyqxmd.com/read/28463032/assessing-nanomaterial-exposures-in-aquatic-ecotoxicological-testing-framework-and-case-studies-based-on-dispersion-and-dissolution
#15
Alan J Kennedy, Jessica G Coleman, Stephen A Diamond, Nicolas L Melby, Anthony J Bednar, Ashley Harmon, Zachary A Collier, Robert Moser
The unique behavior of engineered nanomaterials (ENM) in aqueous media and dynamic changes in particle settling, agglomeration and dissolution rates is a challenge to the consistency, reliability and interpretation of standard aquatic hazard bioassay results. While the toxicological endpoints (e.g., survival, growth, reproduction, etc.) in ecotoxicity bioassays are largely applicable to ENMs, the standard methods as written for dissolved substances are confounded by the dynamic settling, agglomeration and dissolution of particulate ENMs during the bioassay...
May 2, 2017: Nanotoxicology
https://www.readbyqxmd.com/read/28458681/elevation-shift-in-abies-mill-pinaceae-of-subtropical-and-temperate-china-and-vietnam-corroborative-evidence-from-cytoplasmic-dna-and-ecological-niche-modeling
#16
Yi-Zhen Shao, Xian-Chun Zhang, Loc Ke Phan, Qiao-Ping Xiang
The "elevational shift" scenario has been proposed as a model to explain the response of cold-adapted organisms to Quaternary climatic fluctuations in Europe and North America. However, the elevational shift model has not been well-explored in eastern Asia, which is more topographically complex than the other Northern Hemisphere biogeographic regions. Here, we evaluated the role of elevational shift in the closely related firs, or Abies Mill., of subtropical and temperate China. These firs are typical alpine trees with sensitivity to climate change...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28453463/the-igf-i-jak2-stat3-mir-21-signaling-pathway-may-be-associated-with-human-renal-cell-carcinoma-cell-growth
#17
Ying Su, An Zhao, Guoping Cheng, Jingjing Xu, Enming Ji, Wenyong Sun
BACKGROUND: Renal cell carcinoma (RCC) is the highest mortality rate of the genitourinary cancers, and the treatment options are very limited. Thus, identification of molecular mechanisms underlying RCC tumorigenesis, is critical for identifying biomarkers for RCC diagnosis and prognosis. OBJECTIVE: To validate whether the IGF-I/JAK2-STAT3/miR-21 signaling pathway is associated with human RCC cell growth. METHODS: qRT-PCR and Western blotting were used to detect the mRNA and protein expression levels, respectively...
April 21, 2017: Cancer Biomarkers: Section A of Disease Markers
https://www.readbyqxmd.com/read/28450747/accessible-areas-in-ecological-niche-comparisons-of-invasive-species-recognized-but-still-overlooked
#18
Huijie Qiao, Luis E Escobar, A Townsend Peterson
Understanding biological invasions is crucial for their control and prevention. Specially, establishing whether invasive species operate within the constraint of conservative ecological niches, or if niche shifts occur at all commonly as part of the invasion process, is indispensable to identifying and anticipating potential areas of invasion. Ecological niche modeling (ENM) has been used to address such questions, but improvements and debate in study design, model evaluation, and methods are still needed to mature this field...
April 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28443660/assessing-the-risk-of-engineered-nanomaterials-in-the-environment-development-and-application-of-the-nanofate-model
#19
Kendra L Garner, Sangwon Suh, Arturo A Keller
We developed a dynamic multimedia fate and transport model (nanoFate) to predict the time-dependent accumulation of metallic engineered nanomaterials (ENMs) across environmental media. nanoFate considers a wider range of processes and environmental subcompartments than most previous models and considers ENM releases to compartments (e.g., urban, agriculture) in a manner that reflects their different patterns of use and disposal. As an example, we simulated ten years of release of nano CeO2, CuO, TiO2, and ZnO in the San Francisco Bay area...
May 5, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28441862/spatial-temporal-dispersion-of-aerosolized-nanoparticles-during-the-use-of-consumer-spray-products-and-estimates-of-inhalation-exposure
#20
Jihoon Park, Seunghon Ham, Miyeon Jang, Jinho Lee, Sunju Kim, Sungkyoon Kim, Kiyoung Lee, Donguk Park, Jung-Taek Kwon, Hyunmi Kim, Pilje Kim, Kyunghee Choi, Chungsik Yoon
We evaluated the spatial-temporal dispersion of airborne nanomaterials during the use of spray consumer products and estimated the level of consumer inhalation exposure. A total of eight spray products including five propellant and three pump types were selected to evaluate the dispersion of airborne nanoparticles across time and space in a cleanroom which could control the background particles. Four products were advertised to contain silver and one contained titanium nanoparticles, while three products were specified no ENM but as being manufactured through the use of nanotechnology...
April 25, 2017: Environmental Science & Technology
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