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Endometritis

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https://www.readbyqxmd.com/read/29135348/development-of-a-surgical-infection-surveillance-program-at-a-tertiary-hospital-in-ethiopia-lessons-learned-from-two-surveillance-strategies
#1
Jared A Forrester, Luca Koritsanszky, Benjamin D Parsons, Menbere Hailu, Demisew Amenu, Seifu Alemu, Fekadu Jiru, Thomas G Weiser
BACKGROUND: Surgical site infections (SSIs) are a leading cause of post-operative morbidity and mortality. We developed Clean Cut, a surgical infection prevention program, with two goals: (1) Increase adherence to evidence-based peri-operative infection prevention standards and (2) establish sustainable surgical infection surveillance. Here we describe our infection surveillance strategy. PATIENTS AND METHODS: Clean Cut was piloted and evaluated at a 523 bed tertiary hospital in Ethiopia...
November 14, 2017: Surgical Infections
https://www.readbyqxmd.com/read/29135053/chronic-endometritis-in-patients-with-unexplained-infertility-prevalence-and-effects-of-antibiotic-treatment-on-spontaneous-conception
#2
Ettore Cicinelli, Maria Matteo, Giueseppe Trojano, Paola C Mitola, Raffaele Tinelli, Amerigo Vitagliano, Francesco M Crupano, Achiropita Lepera, Giuseppe Miragliotta, Leonardo Resta
PROBLEM: The correlations between chronic endometritis and unexplained infertility are unexplored. METHOD OF STUDY: We performed a retrospective study on consecutive patients referred to our hysteroscopy service due to unexplained infertility. All women underwent endometrial sampling with histological and cultural examinations. If chronic endometritis was diagnosed, patients received antibiotic therapy, and chronic endometritis resolution was subsequently ascertained by histological examination...
November 14, 2017: American Journal of Reproductive Immunology: AJRI
https://www.readbyqxmd.com/read/29134697/cytological-endometritis-diagnosed-at-artificial-insemination-in-repeat-breeder-dairy-cows
#3
O Bogado Pascottini, M Hostens, G Opsomer
This study aimed to (i) assess the prevalence of cytological endometritis (CYTO) diagnosed at artificial insemination (AI); (ii) evaluate the effect of CYTO on the pregnancy outcome of the same AI sample; and (iii) determine the risk factors associated with CYTO diagnosed at AI in repeat breeder (RB) dairy cows. We analysed the productive and reproductive performances of 146 RB Holstein-Friesian cows. To obtain a CYTO sample at AI, we used the cytotape technique. Generalized mixed effect models were computed to find the risk factors associated with the pregnancy and CYTO outcome...
November 14, 2017: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/29124818/diagnosis-and-management-of-patients-with-enhanced-myometrial-vascularity-associated-with-retained-products-of-conception
#4
Yvette S Groszmann, Amie Lynn Healy Murphy, Beryl R Benacerraf
OBJECTIVES: We performed this study to assess the complication rate, including the estimated amount of blood loss, in patients who underwent dilation and curettage for treatment of retained products of conception with markedly enhanced myometrial vascularity mimicking arteriovenous malformations. METHODS: This is a retrospective medical records review study of patients with retained products of conception with enhanced myometrial vascularity presenting to our ultrasound unit between August 1, 2015 and August 1, 2017...
November 10, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29119338/elevated-levels-of-adma-are-associated-with-lower-ddah2-and-higher-prmt1-in-lps-induced-endometritis-rats
#5
Hong-Bo Xiao, Guo-Guang Sui, Xiang-Yang Lu, Zhi-Liang Sun
Chronic endometritis is a continuous inflammation of uterine endometrium. Recent research has shown that higher asymmetric dimethylarginine (ADMA) levels contribute to endothelial dysfunction. In the present study, we tested whether there is a correlation between endometritis and ADMA in LPS-induced endometritis rat and the mechanisms involved. Thirty-six rats were divided into two groups: blank control group and rat model of endometritis group. The entire infused uterus were removed to observe the changes of histopathology, production of myeloperoxidase (MPO), tumor necrosis factor-α (TNF-α), interleukin (IL)-6, 8-isoprostane, and reactive oxygen species (ROS), and gene expression of dimethylarginine dimethylaminohydrolase 2 (DDAH2), protein-methyl transferase 1 (PRMT1), TNF-α, and IL-6...
November 8, 2017: Inflammation
https://www.readbyqxmd.com/read/29112658/adding-azithromycin-to-cephalosporin-for-cesarean-delivery-infection-prophylaxis-a-cost-effectiveness-analysis
#6
Ashley E Skeith, Brenda Niu, Amy M Valent, Methodius G Tuuli, Aaron B Caughey
OBJECTIVE: To investigate the cost-effectiveness of adding azithromycin to standard cephalosporin regimens of cesarean delivery prophylaxis by considering the maternal outcomes in the current and potential subsequent pregnancies. METHODS: A cost-effectiveness model was created using TreeAge to compare the outcomes of using azithromycin-cephalosporin with cephalosporin alone in a theoretical cohort of 700,000 women, the approximate number of nonelective cesarean deliveries annually in the United States that occur during labor or after membrane rupture...
November 3, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29111313/prevalence-and-confounders-of-chronic-endometritis-in-premenopausal-women-with-abnormal-bleeding-or-reproductive-failure
#7
Dongmei Song, Xiangdong Feng, Qian Zhang, Enlan Xia, Yu Xiao, Wei Xie, Tin Chiu Li
In this retrospective cohort study, a consecutive series of 1551 premenopausal women underwent hysteroscopy and endometrial biopsy. Chronic endometritis was diagnosed when plasma cell in endometrial tissue was detected by immunohistochemistry using CD138 epitope. The overall prevalence of chronic endometritis in the population studied was 24.4% The prevalence was significantly increased in the following conditions: recurrent implantation failure (40.8%; P < 0.001), abnormal uterine bleeding (40.7 %; P < 0...
October 6, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/29104078/eucalyptus-robusta-leaves-methanolic-extract-suppresses-inflammatory-mediators-by-specifically-targeting-tlr4-tlr9-mpo-cox2-inos-and-inflammatory-cytokines-in-experimentally-induced-endometritis-in-rats
#8
Aastha Tiwari, Preeti Singh, Pooja Jaitley, Sushant Sharma, Atul Prakash, Rajesh Mandil, Soumen Choudhury, Neeraj Kumar Gangwar, Satish K Garg
ETHNOPHARMACOLOGICAL RELEVANCE: Bacterial endometritis is one of the major causes of reproductive disorders including infertility in farm animals. Antibiotics are generally used for treatment of such disorders but now a days residues of antibiotics are of great public health concern, therefore, phytoremediation is being considered as an alternative to use of antibiotics. AIM OF THE STUDY: Present study was undertaken to investigate the efficacy of Eucalyptus robusta leaves methanolic extract against endometritis along with the possible mechanism of action especially targeting inflammatory biomarkers...
November 2, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29096053/antibiotic-prophylaxis-for-episiotomy-repair-following-vaginal-birth
#9
REVIEW
Mercedes Bonet, Erika Ota, Chioma E Chibueze, Olufemi T Oladapo
BACKGROUND: Bacterial infections occurring during labour, childbirth, and the puerperium may be associated with considerable maternal and perinatal morbidity and mortality. Antibiotic prophylaxis might reduce wound infection incidence after an episiotomy, particularly in situations associated with a higher risk of postpartum perineal infection, such as midline episiotomy, extension of the incision, or in settings where the baseline risk of infection after vaginal birth is high. However, available evidence is unclear concerning the role of prophylactic antibiotics in preventing infections after an episiotomy...
November 2, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29078736/leptrotrichia-amnionii-an-emerging-pathogen-of-postpartum-endometritis
#10
Tine Masschaele, Sophia Steyaert, Ronny Goethals
Leptotrichia amnionii, a recently described fastidious gram-negative anaerobic bacterium, is an opportunistic pathogen of the female urogenital tract. We report a rare case of L. amnionii bacteremia in a patient with postpartum endometritis which was successfully treated by amoxicilline-clavunalate. There is more and more evidence that L. amnonii has its role in Pelvic Inflammatory Disease and postpartum endometritis.
October 27, 2017: Acta Clinica Belgica
https://www.readbyqxmd.com/read/29056743/exfoliative-endometrial-cytology-in-embryo-donor-cows-comparison-of-sampling-localizations-for-the-diagnosis-of-subclinical-endometritis
#11
Janna Egberts, Jan Detterer, Arno Park, Sabine Meinecke-Tillmann
Subclinical endometritis has a major effect on the reproductive performance of dairy cows and also on the success of embryo collection. Thus it is important to minimize the number of false-negative diagnoses. In order to evaluate the question of whether or not a single cytobrush sample is representative of the whole endometrium, 53 German Holstein embryo donor cows in the northwest of Germany were examined via the cytobrush method at three different localizations of the uterus: the uterine body about 0.5 cm cranial of the cervical canal and both uterine horns about 1...
November 28, 2016: Veterinary Sciences
https://www.readbyqxmd.com/read/29055723/proteomics-and-metabolomics-characterizing-the-pathophysiology-of-adaptive-reactions-to-the-metabolic-challenges-during-the-transition-from-late-pregnancy-to-early-lactation-in-dairy-cows
#12
Fabrizio Ceciliani, Cristina Lecchi, Christiane Urh, Helga Sauerwein
The transition from late pregnancy to early lactation is a critical period in a dairy cow's life due to the rapidly increasing drain of nutrients from the maternal organism towards the foetus and into colostrum and milk. In order to cope with the challenges of parturition and lactation, comprehensive adaptive reactions comprising the endocrine and the immune system need to be accomplished. There is high variation in this coping ability and both metabolic and infectious diseases, summarized as "production diseases", such as hypocalcaemia (milk fever), fatty liver syndrome, laminitis and ketosis, may occur and impact welfare, productive lifespan and economic outcomes...
October 18, 2017: Journal of Proteomics
https://www.readbyqxmd.com/read/29020834/high-transverse-skin-incisions-may-reduce-wound-complications-in-obese-women-having-cesarean-sections-a-pilot-study
#13
Robert B Walton, Kelsey L Shnaekel, Songthip T Ounpraseuth, Peter G Napolitano, Everett F Magann
OBJECTIVE: Women having cesarean section have a high risk of wound complications. Our objective was to determine whether high transverse skin incisions are associated with a reduced risk of cesarean wound complications in women with BMI greater than 40. METHODS: A retrospective cohort study was undertaken of parturients ages 18-45 with BMI greater than 40 having high transverse skin incisions from January 2010 to April 2015 at a tertiary maternity hospital. Temporally matched controls had low transverse skin incisions along with a BMI greater than 40...
November 1, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28994097/reliability-of-histopathological-examination-and-immunohistochemistry-of-a-single-biopsy-for-evaluation-of-endometrial-health-in-icelandic-mares
#14
Monika Sikora, Marcin Nowak, Henryk Racheniuk, Katarzyna Wojtysiak, Roland Kozdrowski
INTRODUCTION: Endometritis and endometrosis have been and still are the major reasons for infertility in mares. The diagnosis of endometritis can be based on cytology and microbiology, but endometrial biopsy is still the only way to diagnose endometrosis in the mare. Our study attempted to determine if a single biopsy using histopathology and immunohistochemistry is sufficient to ascertain reasons for infertility in Icelandic mares. The objectives of this study were to examine the relationship between deviations in endometrial biopsies in terms of prostaglandin-endoperoxide synthase-2 (PTGS-2) and fibronectin expression and polymorphonuclear cells (PMNs) infiltration, as well as scoring degeneration in two endometrial biopsies...
October 10, 2017: Folia Histochemica et Cytobiologica
https://www.readbyqxmd.com/read/28993281/two-miscarriages-consecutive-or-non-consecutive-does-it-change-something
#15
C Cardinale, J Berbis, C Chau, F Bernard, D Arnoux, M-F Fratacci, L Boubli, F Bretelle
OBJECTIVES: To assess the rate of anomalies in the etiological evaluation of patients presenting recurrent early miscarriages (RM) according to miscarriage chronology (number of miscarriages, history of live birth and succession of RM). METHODS: Retrospective single centre study including RM, defined as at least 2 miscarriages at less than 14 weeks of gestation (WG) between the 1st January 2012 and the 31st December 2015. Clinical data and etiological evaluation include blood glucose levels, screening for antiphospholipid syndrome (APS), endocrine assessment, vitamin levels, pelvic imaging, karyotyping of both partners, chronic endometritis and thrombophilia screening...
October 6, 2017: Journal of gynecology obstetrics and human reproduction
https://www.readbyqxmd.com/read/28976128/an-incidental-finding-of-chronic-salpingitis-complications-tubo-uterine-fistula
#16
Aytekin Tokmak, Alev Esercan, Esma Sarıkaya
Pelvic inflammatory disease (PID) is an infection of the upper genital tract in women that can include endometritis, parametritis, salpingitis, oophoritis, tubo-ovarian abscess, and peritonitis. The spectrum of the disease ranges from subclinical and asymptomatic infection to severe, lifethreatening illness; squealae include chronic pelvic pain, ectopic pregnancy, and infertility. In this case we report an uncommon complication of pelvic inflammatory disease, a tubo-uterian fistula. Our case was diagnosed by laparoscopy incidentally during assessment of infertility...
September 2017: Journal of Experimental Therapeutics & Oncology
https://www.readbyqxmd.com/read/28970274/a-model-of-equine-endometritis-involving-a-pseudomonas-aeruginosa-biofilm
#17
Ryan A Ferris, Patrick M McCue, Grace I Borlee, Kristina E Glapa, Kevin H Martin, Mihnea R Mangalea, Margo L Hennet, Lisa M Wolfe, Corey D Broeckling, Bradley R Borlee
Bacteria in a biofilm community have increased tolerance to antimicrobial therapy. To characterize the role of biofilms in equine endometritis, six mares were inoculated with lux-engineered Pseudomonas aeruginosa strains isolated from equine uterine infections. Following establishment of infection, the horses were euthanized and the endometrial surfaces were imaged for luminescence to localize adherent lux-labeled bacteria. Samples from the endometrium were collected for cytology, histopathology, carbohydrate analysis, and expression of inflammatory cytokine genes...
October 2, 2017: Infection and Immunity
https://www.readbyqxmd.com/read/28955083/pelvic-abscess-caused-by-a-slow-growing-anaerobic-bacterium-eggerthella-lenta-first-case-report-from-pakistan
#18
Pushpa Bhawan Mal, Irum Rafiq, Irim Iftikhar, Seema Irfan
We report a case of intrauterine contraceptive device (IUCD) related pelvic abscess caused by a challenging to grow anaerobic Gram positive rod named Eggerthella lenta. A middle aged lady presented with complaints of lower abdomen pain, intermittent vaginal bleeding since two weeks. Ultrasound of abdomen and pelvis showed right adnexal mass involving fallopian tubes, right ovary and gut omentum. She underwent removal of adnexal mass and total abdominal hysterectomy and was treated empirically with vancomycin, ciprofloxacin and metronidazole...
October 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28951263/prophylactic-negative-pressure-wound-therapy-after-cesarean-is-associated-with-reduced-risk-of-surgical-site-infection-a%C3%A2-systematic-review-and-meta-analysis
#19
REVIEW
Lulu Yu, Ryan J Kronen, Laura E Simon, Carolyn R T Stoll, Graham A Colditz, Methodius G Tuuli
OBJECTIVE: The objective of the study was to assess the effect of prophylactic negative-pressure wound therapy on surgical site infections and other wound complications in women after cesarean delivery. DATA SOURCES: We searched Ovid Medline, Embase, SCOPUS, Cochrane Database of Systematic Reviews, and ClinicalTrials.gov. STUDY ELIGIBILITY CRITERIA: We included randomized controlled trials and observational studies comparing prophylactic negative-pressure wound therapy with standard wound dressing for cesarean delivery...
September 23, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28937705/interventions-for-treating-genital-chlamydia-trachomatis-infection-in-pregnancy
#20
REVIEW
Catherine Cluver, Natalia Novikova, David Oa Eriksson, Kevin Bengtsson, Göran K Lingman
BACKGROUND: Genital Chlamydia trachomatis (C.trachomatis) infection may lead to pregnancy complications such as miscarriage, preterm labour, low birthweight, preterm rupture of membranes, increased perinatal mortality, postpartum endometritis, chlamydial conjunctivitis and C.trachomatis pneumonia.This review supersedes a previous review on this topic. OBJECTIVES: To establish the most efficacious and best-tolerated therapy for treatment of genital chlamydial infection in preventing maternal infection and adverse neonatal outcomes...
September 22, 2017: Cochrane Database of Systematic Reviews
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