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Probiotics

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https://www.readbyqxmd.com/read/29683763/saccharomyces-cerevisiae-based-probiotic-as-novel-anti-microbial-agent-for-therapy-of-bacterial-vaginosis
#1
Samuele Sabbatini, Claudia Monari, Nathalie Ballet, Paolo Mosci, Amélie Cayzeele Decherfe Fanny Pélerin, Stefano Perito, Paolo Scarpelli, Anna Vecchiarelli
In this study, we demonstrate, for the first time, that Saccharomyces cerevisiae-based probiotic shows an inhibitory effect on Gardnerella vaginalis infection. This effect is likely due to several actions: direct interference with adherence to vaginal tissues, inhibition of sialidase activity, reduction of vaginal epithelial exfoliation. Gardnerella vaginalis does not induce vaginal inflammation and no inflammatory cytokines were, indeed, produced, by the mouse vagina, neither by Gardnerella vaginalis and by the probiotic...
April 23, 2018: Virulence
https://www.readbyqxmd.com/read/29682678/more-protection-of-lactobacillus-acidophilus-than-bifidobacterium-bifidum-probiotics-on-azoxymethane-induced-mouse-colon-cancer
#2
Shahram Agah, Ali Mohammad Alizadeh, Maryam Mosavi, Peyman Ranji, Hossein Khavari-Daneshvar, Farnaz Ghasemian, Sahar Bahmani, Abbas Tavassoli
Based on the ability of the probiotics in the gut microflora modification, they can have the beneficial effects on diseases in the short and/or the long term. In previous study, we revealed that unlike Bifidobacterium bifidum, the amount of Lactobacillus acidophilus remained almost unchanged in mice gut microflora in the long term, indicating more stability of L. acidophilus than B. bifidum which can be used to prevent some incurable diseases such as cancer. Thirty-eight male BALB/c mice were divided into four groups, control, azoxymethane (AOM), L...
April 22, 2018: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29682542/gut-microbial-changes-interactions-and-their-implications-on-human-lifecycle-an-ageing-perspective
#3
REVIEW
Ravichandra Vemuri, Rohit Gundamaraju, Madhur D Shastri, Shakti Dhar Shukla, Krishnakumar Kalpurath, Madeleine Ball, Stephen Tristram, Esaki M Shankar, Kiran Ahuja, Rajaraman Eri
Gut microbiota is established during birth and evolves with age, mostly maintaining the commensal relationship with the host. A growing body of clinical evidence suggests an intricate relationship between the gut microbiota and the immune system. With ageing, the gut microbiota develops significant imbalances in the major phyla such as the anaerobic Firmicutes and Bacteroidetes as well as a diverse range of facultative organisms, resulting in impaired immune responses. Antimicrobial therapy is commonly used for the treatment of infections; however, this may also result in the loss of normal gut flora...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29682272/maintenance-of-fish-health-in-aquaculture-review-of-epidemiological-approaches-for-prevention-and-control-of-infectious-disease-of-fish
#4
REVIEW
Ayalew Assefa, Fufa Abunna
Aquaculture is rapidly growing part of agriculture worldwide. It makes up around 44 percent of total fish production globally. This increased growth of production is achieved despite facing many challenges in the aquaculture environment. Among production limiting challenges, the infectious disease takes the lion share by causing multibillion-dollar loss annually. To reduce the impact of the fish disease, it is necessary to address health constraints based on scientifically proven and recommended ways. This review aims at pointing out some of the best approaches to prevention and control of infectious disease in aquaculture...
2018: Veterinary Medicine International
https://www.readbyqxmd.com/read/29681147/transcriptomic-analysis-of-xylan-oligosaccharides-utilization-systems-in-pediococcus-acidilactici-strain-bcc-1
#5
Zhao Lei, Yu Qin Wu, Wei Nie, Dafei Yin, Xiaonan Yin, Yuming Guo, Samuel Aggrey, Jianmin Yuan
Xylanoligosaccharides (XOS) is the hydrolysates of xylan. To compare the proliferation effect of XOS, glucose, fructooligosaccharides (FOS), xylose, XOS and a media without carbohydrate source (control) on Pediococcus acidilactici strain BCC-1. The de-novo sequencing of Pediococcus acidilactici strain BCC-1 was conducted, and the underlying mechanism of prebiotic xylooligosaccharide between xylose and XOS was revealed through transcriptomic analysis. Compared to FOS, glucose and xylose, XOS exhibits a good performance in promoting the fermentation of Pediococcus acidilactici BCC-1...
April 22, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29680883/effect-of-dietary-supplementation-of-zinc-and-multi-microbe-probiotic-on-growth-traits-and-alteration-of-intestinal-architecture-in-broiler
#6
Muqader Shah, Hafsa Zaneb, Saima Masood, Rifat Ullah Khan, Saima Ashraf, Arbab Sikandar, Hafiz Faseeh Ur Rehman, Habib Ur Rehman
This experiment aimed to investigate the effect of different levels of zinc (Zn) and a probiotic on the growth and intestinal health of broiler chickens. One hundred ninety-two-day-old broiler chicks were randomly assigned to 6 groups. The birds were supplemented with Zn (30 and 60 mg/kg) and a probiotic mixture alone or in combination with Zn. The results revealed that the broilers receiving a probiotic mixture alone or in combination with Zn (30 and 60 mg) increased (P < 0.05) final body weight, feed conversion ratio (FCR), and total goblet cell count in duodenum compared with the control group...
April 22, 2018: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29680882/production-of-phytase-enzyme-by-a-bioengineered-probiotic-for-degrading-of-phytate-phosphorus-in-the-digestive-tract-of-poultry
#7
Bahareh Pakbaten, Reza Majidzadeh Heravi, Hassan Kermanshahi, Mohammad-Hadi Sekhavati, Ali Javadmanesh, Masoud Mohammadi Ziarat
Probiotics are beneficial microorganisms and have long been used in food production as well as health promotion products. Bioengineered probiotics are used to express and transfer native or recombinant molecules to the mucosal surface of the digestive tract to improve feed efficiency and promote health. Lactococcus lactis is a potential probiotic candidate to produce useful biological proteins. The aim of this investigation was to develop a recombinant Lactococcus lactis with the potential of producing phytase...
April 21, 2018: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29680655/enhanced-phagocytosis-of-aggregatibacter-actinomycetemcomitans-cells-by-macrophages-activated-by-a-probiotic-lactobacillus-strain
#8
N Jaffar, T Okinaga, T Nishihara, T Maeda
The activation of phagocytosis is one important approach to clearing pathogenic cells in a host. This study evaluated the ability of probiotic lactobacilli to induce phagocytic activity as well as the clearance of a periodontal pathogen, Aggregatibacter actinomycetemcomitans. First, the activation of phagocytosis was found by using lyophilized dead cells. Probiotic Lactobacillus strains significantly enhanced the phagocytic activity of macrophage cells, indicating that the probiotic lactobacilli have a remarkable ability to stimulate the macrophages...
April 18, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29679417/a-probiotic-modulates-the-microbiome-and-immunity-in-multiple-sclerosis
#9
Stephanie K Tankou, Keren Regev, Brian C Healy, Emily Tjon, Luca Laghi, Laura M Cox, Pia Kivisäkk, Isabelle V Pierre, Hrishikesh Lokhande, Roopali Gandhi, Sandra Cook, Bonnie Glanz, James Stankiewicz, Howard L Weiner
OBJECTIVE: Effect of a probiotic on the gut microbiome and peripheral immune function in healthy controls and relapsing-remitting multiple sclerosis (RRMS) patients. METHODS: MS patients (N=9) and controls (N=13) were orally administered a probiotic containing Lactobacillus, Bifidobacterium and Streptococcus twice daily for two months. Blood and stool specimens were collected at baseline, after completion of the 2-month treatment, and 3 months after discontinuation of therapy...
April 20, 2018: Annals of Neurology
https://www.readbyqxmd.com/read/29678738/autochthonous-lactic-acid-bacteria-isolated-from-pig-faeces-in-thailand-show-probiotic-properties-and-antibacterial-activity-against-enteric-pathogenic-bacteria
#10
Wandee Sirichokchatchawan, Puwiya Pupa, Prasert Praechansri, Nutthee Am-In, Somboon Tanasupawat, Piengchan Sonthayanon, Nuvee Prapasarakul
Lactic acid bacteria (LAB) play an important role in pig health and performance that arises from their beneficial impacts on the balance of gastrointestinal microbes, ability to fight enteric pathogens, and capacity to support the immune system. The aim of this study was to evaluate the functional and safety aspects of five previously isolated autochthonous LAB strains, (Lactobacillus plantarum 22F, 25F and 31F, Pediococcus acidilactici 72N and Pediococcus pentosaceus 77F) from pig faeces as potential probiotics for a pig feed supplement...
April 17, 2018: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29678466/cost-effectiveness-analysis-of-oral-probiotics-for-the-prevention-of-clostridium-difficile-associated-diarrhoea-in-children-and-adolescents
#11
Na Li, Bin Zheng, Hong-Fu Cai, Yan-Hui Chen, Ming-Qi Qiu, Mao-Bai Liu
BACKGROUND: The incidence of Clostridium difficile-associated diarrhoea (CDAD) in hospitalized children and adolescents has been increasing year-on-year. Paediatric CDAD represents a significant economic burden on healthcare systems. Probiotics are live organisms thought to improve the microbial balance of the host, counteract disturbances in intestinal flora, and reduce the risk of colonization by pathogenic bacteria. AIM: We conducted a cost-effectiveness analysis to assess the economy of probiotics for the prevention of CDAD in children and adolescents receiving antibiotics...
April 17, 2018: Journal of Hospital Infection
https://www.readbyqxmd.com/read/29678171/analysis-of-hepatic-transcriptome-demonstrates-altered-lipid-metabolism-following-lactobacillus-johnsonii-bs15-prevention-in-chickens-with-subclinical-necrotic-enteritis
#12
Xiaodan Qing, Dong Zeng, Hesong Wang, Xueqin Ni, Jing Lai, Lei Liu, Abdul Khalique, Kangcheng Pan, Bo Jing
BACKGROUND: Subclinical necrotic enteritis (SNE) widely outbreaks in chickens which inflicted growth-slowing, causing enormous social and economic burdens. To better understand the molecular underpinnings of SNE on lipid metabolism and explore novel preventative strategies against SNE, we studied the regulatory mechanism of a potential probiotic, Lactobacillus johnsonii BS15 on the lipid metabolism pathways involved in chickens with SNE. METHODS: One hundred eighty one-day-old chickens were randomly divided into three groups and arranged with basal diet (control and SNE group)...
April 20, 2018: Lipids in Health and Disease
https://www.readbyqxmd.com/read/29676842/rhizosphere-pseudomonads-as-probiotics-improving-plant-health
#13
REVIEW
Young Cheol Kim, Anne J Anderson
Many root-colonizing microbes are multifaceted in traits that improve plant health. Although isolates designated as biological control agents directly reduce pathogen growth, many exert additional beneficial features that parallel changes induced in animal and other hosts by health-promoting microbes termed probiotics. Both animal and plant probiotics cause direct antagonism of pathogens and induce systemic immunity in the host to pathogens and other stresses. They also alter host development, and improve host nutrition...
April 20, 2018: Molecular Plant Pathology
https://www.readbyqxmd.com/read/29676446/an-approach-on-the-potential-use-of-probiotics-in-the-treatment-of-skin-conditions-acne-and-atopic-dermatitis
#14
REVIEW
Vitória H M Mottin, Edna S Suyenaga
Acne and Atopic Dermatitis (AD) are chronic inflammatory skin conditions with severe impact on a patient's life. Current treatments are related to adverse effects and do not represent a definitive cure. The present paper reviews the alterations in skin microbiome, specifically in acne and AD, and aims in searching for potential treatments based on benefic microorganisms, called probiotics. The review was made through bibliographic search of the main databases (Science Direct, PubMed, Scielo, Medline) between September 2015 and June 2016...
April 20, 2018: International Journal of Dermatology
https://www.readbyqxmd.com/read/29675053/the-potential-effect-of-chinese-herbal-formula-hongqijiangzhi-fang-in-improving-nafld-focusing-on-nlrp3-inflammasome-and-gut-microbiota
#15
Shu Liang, Yupei Zhang, Yuanjun Deng, Yifang He, Yinji Liang, Zien Liang, Yanning Chen, Kairui Tang, Runsen Chen, Qinhe Yang
The present study investigates the potential therapeutic mechanism underlying the effects of the Chinese herbal formula Hongqijiangzhi Fang (HJF) on nonalcoholic fatty liver disease (NAFLD) in rats. Male Sprague Dawley (SD) rats were randomly divided into 4 groups ( n = 8): control group was fed a normal diet, three other groups were fed high-fat diets (HFD), and the two treatment groups were intragastrically given a compound probiotic or HJF during the molding time. After 16 w, related indices were detected...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29674267/anti-inflammatory-effect-of-multistrain-probiotic-formulation-l-rhamnosus-b-lactis-and-b-longum
#16
Marzia Sichetti, Stefania De Marco, Rita Pagiotti, Giovanna Traina, Donatella Pietrella
OBJECTIVE: In recent years, a great number of studies have been directed toward the evaluation of gastrointestinal microbiota modulation through the introduction of beneficial microorganisms, also known as probiotics. Many studies have highlighted how this category of bacteria is very important for the good development, functioning, and maintenance of our immune system. There is a delicate balance between the immune system, located under the gut epithelial barrier, and the microbiota, but many factors can induce a disequilibrium that leads to an inflammatory state and dysbiosis...
February 14, 2018: Nutrition
https://www.readbyqxmd.com/read/29673790/molecular-detection-and-quantification-of-viable-probiotic-strains-in-animal-feedstuffs-using-the-commercial-direct-fed-microbial-lactobacillus-animalis-np51-as-a-model
#17
D I Ayala, J Chen, M Bugarel, G H Loneragan, H C den Bakker, K R Kottapalli, M M Brashears, K K Nightingale
Lactobacillus animalis NP51 is a direct-fed microbial strain (DFM) extensively used as a pre-harvest food safety mitigation in feedlot cattle due to its antagonistic effects against human foodborne pathogens such as Salmonella and Escherichia coli O157:H7. NP51 not only promotes overall gut health but interferes with the ability of these pathogens to colonize the gastrointestinal tract of cattle. As a result, NP51 reduces fecal shedding of Salmonella and E. coli O157:H7 in cattle presented for harvest and the load of these pathogens that enter the human food chain...
April 16, 2018: Journal of Microbiological Methods
https://www.readbyqxmd.com/read/29673353/modulation-of-ovine-sbd-1-expression-by-saccharomyces-cerevisiae-in-ovine-ruminal-epithelial-cells
#18
Xin Jin, Man Zhang, Xue-Min Zhu, Yan-Ru Fan, Chen-Guang Du, Hua-Er Bao, Siri-Guleng Xu, Qiao-Zhen Tian, Yun-He Wang, Yin-Feng Yang
BACKGROUND: The ovine rumen is involved in host defense responses and acts as the immune interface with the environment. The ruminal mucosal epithelium plays an important role in innate immunity and secretes antimicrobial innate immune molecules that have bactericidal activity against a variety of pathogens. Defensins are cationic peptides that are produced by the mucosal epithelia and have broad-spectrum antimicrobial activity. Sheep β-defensin-1 (SBD-1) is one of the most important antibacterial peptides in the rumen...
April 19, 2018: BMC Veterinary Research
https://www.readbyqxmd.com/read/29672225/probiotic-supplementation-in-trained-trotter-horses-effect-on-blood-clinical-pathology-data-and-urine-metabolomic-assessed-in-field
#19
Luca Laghi, Chenglin Zhu, Giuseppe Campagna, Giacomo Rossi, Marilena Bazzano, Fulvio Laus
The attention of sports community towards probiotic supplementation as a way to promote exercise and training performance, together with good health, has increased in recent years. This has applied also to horses, with promising results. Here, for the first time, we tested a probiotic mix of several strains of alive bacteria typically employed for humans to improve the training performance of Standardbred horses in athletic activity. To evaluate its effects on the horse performance, we measured lactate concentration in blood, a translational outcome largely employed for the purpose, combined with the study of hematological and biochemical parameters, together with urine from a metabolomics perspective...
April 19, 2018: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29672196/the-effects-of-synbiotic-supplementation-on-body-mass-index-metabolic-and-inflammatory-biomarkers-and-appetite-in-patients-with-metabolic-syndrome-a-triple-blind-randomized-controlled-trial
#20
Samira Rabiei, Mehdi Hedayati, Bahram Rashidkhani, Navid Saadat, Rahebeh Shakerhossini
It has been shown recently that metabolic syndrome is associated with gut dysbiosis. The gut microbiota may be the main target for prevention or treatment of metabolic syndrome. We investigated the effects of synbiotic supplementation on metabolic syndrome. In this triple-blinded clinical trial, 46 Iranian patients with metabolic syndrome, from both sexes, aged 25-70 years, who fulfilled inclusion criteria were randomly categorized to receive either the synbiotic or a placebo capsule, twice a day for three months, plus a weight-loss diet using stratified random sampling based on body mass index (BMI)...
April 19, 2018: Journal of Dietary Supplements
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