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https://www.readbyqxmd.com/read/29313146/long-term-quality-of-life-after-cytoreductive-surgery-and-heated-intraperitoneal-chemotherapy-for-pseudomyxoma-peritonei-a-prospective-longitudinal-study
#1
Adam T Stearns, Lee Malcomson, Grant Punnett, Haytham Abudeeb, Omer Aziz, Chelliah R Selvasekar, Paul E Fulford, Malcolm S Wilson, Andrew G Renehan, Sarah T O'Dwyer
BACKGROUND: Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) are an established treatment for pseudomyxoma peritonei (PMP), but it is a major surgical procedure and may be associated with long-term morbidity. To date, health-related quality-of-life (HRQL) data among survivors are lacking. METHODS: A two-period qualitative study investigated patients undergoing CRS-HIPEC for PMP at a national peritoneal tumor center between 2003 and 2011...
January 8, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29249764/lupus-nephritis-with-thymoma-managed-by-thoracoscopic-surgery-and-prednisolone
#2
Takashi Iijima, Junichi Hoshino, Kenmei Takaichi, Tadashi Kohno, Takeshi Fujii, Kenichi Ohashi, Yoshifumi Ubara
A 48-year-old woman was admitted to our hospital to undergo evaluation for fatigue, severe weight loss, and nephrotic range proteinuria. Light microscopy of a renal biopsy specimen revealed class III (A) lupus nephritis, while immunofluorescence and electron microscopy only showed sparse immune deposits with findings that were not typical of lupus nephritis. Computed tomography revealed a mass in the anterior mediastinum, which was resected. The examination of the surgical specimen revealed type A noninvasive thymoma...
2017: Internal Medicine
https://www.readbyqxmd.com/read/29249742/-analysis-of-advanced-or-postoperative-recurrent-non-small-lung-cancer-cases-treated-with-nivolumab
#3
Yoshinobu Ichiki, Takashi Iwanami, Kesei Kakizoe, Takayuki Hamatsu, Taketoshi Suehiro, Kazue Yoneda, Fumihiro Tanaka, Keizo Sugimachi
Recent developments in cancer immunotherapy are remarkable. Many reports have described the clinical effects of immune checkpoint inhibitors (ICIs), supporting their utility as a promising therapy that will achieve prominent effects even in patients resistant to cytotoxic anticancer drugs or gene-targeting therapy. ICIs may also prolong overall survival. We analyzed 10 cases of advanced lung cancer targeted with nivolumab, which is one of ICIs in our hospital and reviewed the literature regarding ICIs. We retrospectively analyzed 10 cases that consisted of 6 males and 4 females, which comprised 7 adenocarcinomas, 2 squamous cell carcinomas and one pleomorphic carcinoma...
2017: Journal of UOEH
https://www.readbyqxmd.com/read/29249649/systematic-review-on-the-impact-of-pancreatoduodenectomy-on-quality-of-life-in-patients-with-pancreatic-cancer
#4
REVIEW
Sven M van Dijk, Hanne D Heerkens, Dorine S J Tseng, Martijn Intven, I Quintus Molenaar, Hjalmar C van Santvoort
BACKGROUND: Patients undergoing pancreatoduodenectomy for pancreatic cancer have a high risk of major postoperative complications and a low survival rate. Insight in the impact of pancreatoduodenectomy on quality of life (QoL) is therefore of great importance. The aim of this systematic review was to assess QoL after pancreatoduodenectomy for pancreatic cancer. METHODS: A systematic review of the literature was performed according to the PRISMA guidelines. A systematic search of all the English literature available in PubMed and Medline was performed...
December 14, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29249231/hemoglobinuric-acute-kidney-injury-in-a-patient-with-a-kinked-prosthetic-aortic-graft%C3%A2
#5
Hema V Sheelvanth, Khaleel A Sayeed, William A Whittier
Acute kidney injury (AKI) due to intravascular hemolysis has been well described in paroxysmal nocturnal hemoglobinuria (PNH) and in cardiac valvular dysfunction. However, reported cases of hemoglobinuric AKI from prosthetic aortic grafts are sparse. We present a case of microangiopathic hemolytic anemia and hemoglobinuric AKI presenting 9 days after repair of an ascending aortic dissection with a prosthetic graft. After an unremarkable recovery following the initial procedure, the patient presented on postoperative day 9 with dyspnea, fatigue, and cola-colored urine...
December 18, 2017: Clinical Nephrology
https://www.readbyqxmd.com/read/29232726/-subtalare-screw-arthroereisis-for-the-treatment-of-symptomatic-flexible-pes-planovalgus
#6
Dariusch Arbab, Daniel Frank, Bertil Bouillon, Christian Lüring, Carsten Wingenfeld, Mona Abbara-Czardybon
Background The purpose of this study was to determine the functional outcomes and radiographic results of the talus-stop screw method as minimally invasive subtalar arthroereisis in pediatric and juvenile flexible flatfoot. Material and Methods We retrospectively evaluated 73 feet from 41 children using the talus stop-screw method, for the period between 2002 and 2011. The age at time of surgery ranged between nine and 14 years. The radiological assessment included measuring the calcaneal pitch, talar declination, talo-first metatarsal angle (Meary) and calcaneal-first metatarsal angle (Costa-Bartani) in the lateral view...
December 12, 2017: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/29231044/a-systematic-review-of-exercise-and-psychosocial-rehabilitation-interventions-to-improve-health-related-outcomes-in-patients-with-bladder-cancer-undergoing-radical-cystectomy
#7
Elke Rammant, Karel Decaestecker, Renée Bultijnck, Nora Sundahl, Piet Ost, Nele S Pauwels, Benedicte Deforche, Ronny Pieters, Valérie Fonteyne
OBJECTIVE: Summarizing the evidence on the effects of pre- and postoperative exercise and psychosocial rehabilitation interventions on patient-reported outcomes (PROs) and physical fitness in bladder cancer patients undergoing radical cystectomy. DATA SOURCES: The Cochrane Central Register of Controlled Trials, MEDLINE, Embase, Web of Science and the Physiotherapy Evidence Database were searched independently by two authors from inception until 10 November 2017...
December 1, 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/29225424/parametric-analysis-of-electromechanical-and-fatigue-performance-of-total-knee-replacement-bearing-with-embedded-piezoelectric-transducers
#8
Mohsen Safaei, R Michael Meneghini, Steven R Anton
Total knee arthroplasty (TKA) is a common procedure in the United States; it has been estimated that about 4 million people are currently living with primary knee replacement in this country. Despite huge improvements in material properties, implant design, and surgical techniques, some implants fail a few years after surgery. A lack of information about in vivo kinetics of the knee prevents the establishment of a correlated intra- and postoperative loading pattern in knee implants. In this study, a conceptual design of an ultra high molecular weight (UHMW) knee bearing with embedded piezoelectric transducers is proposed, which is able to measure the reaction forces from knee motion as well as harvest energy to power embedded electronics...
September 2017: Smart Materials & Structures
https://www.readbyqxmd.com/read/29222890/home-enteral-nutrition-after-minimally-invasive-esophagectomy-can-improve-quality-of-life-and-reduce-the-risk-of-malnutrition
#9
Zixiang Wu, Ming Wu, Qi Wang, Tianwei Zhan, Lian Wang, Saibo Pan, Gang Chen
BACKGROUND AND OBJECTIVES: The potential benefits of home enteral nutrition (HEN) and the effects of HEN on quality of life (QOL) after esophagectomy remain unclear. The aim was to investigate the effect of 3 months HEN on health related QOL and nutritional status of esophageal cancer patients who were preoperatively malnourished. METHODS AND STUDY DESIGN: 142 malnourished (PG-SGA stage B or C) patients with esophageal cancer were assigned to receive Ivor Lewis minimally invasive esophagectomy (MIE group) with laparoscopic jejunal feeding tube placement or open esophagectomy (OE group) with nasojejunal feeding tube placement...
2018: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29200067/randomized-clinical-trial-of-preoperative-high-dose-methylprednisolone-on-postoperative-pain-at-rest-after-laparoscopic-appendectomy
#10
Jakob Kleif, Camilla I Hauge, Jesper Vilandt, Ismail Gögenur
BACKGROUND: Methylprednisolone administered intravenously preoperatively has been shown to reduce pain, nausea, and fatigue after elective surgery. We aimed to show that 125 mg of methylprednisolone given intravenously 30 minutes before laparoscopic surgery for suspected appendicitis would reduce pain at rest during the first 3 postoperative days. METHODS: A multicenter, parallel-group, double-blind, placebo-controlled study was conducted including patients 18 years of age and older with an American Society of Anesthesiologist class of I-III undergoing laparoscopic surgery for suspected appendicitis...
November 30, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29188210/pituitary-ependymoma-10-year-follow-up-after-partial-resection-and-radiation-therapy
#11
Jong Seok Lee, Kwan Ho Cho, Eun Kyung Hong, Sang-Hoon Shin
Ependymoma usually arises within the ventricles and central canal of the spinal cord. These tumors, found in the sellar region, are extremely rare. We report a case of pituitary ependymoma followed up over 10 years. A 59-year-old male patient presented with fatigue, general weakness, erectile dysfunction, and loss of body hair, including pubic hair. Brain magnetic resonance imaging (MRI) revealed a 3.3×3.5×2.3-cm sellar and suprasellar snowman-shaped enhancing mass. The tumor was partially resected via the trans-sphenoidal approach followed by postoperative radiation therapy...
October 2017: Brain Tumor Research and Treatment
https://www.readbyqxmd.com/read/29171831/physical-performance-following-acute-high-risk-abdominal-surgery-a-prospective-cohort-study
#12
Line Rokkedal Jønsson, Lina Holm Ingelsrud, Line Toft Tengberg, Thomas Bandholm, Nicolai Bang Foss, Morten Tange Kristensen
BACKGROUND: Acute high-risk abdominal (AHA) surgery is associated with high mortality, multiple postoperative complications and prolonged hospital stay. Further development of strategies for enhanced recovery programs following AHA surgery is needed. The aim of this study was to describe physical performance and barriers to independent mobilization among patients who received AHA surgery (postoperative days [POD] 1-7). METHODS: Patients undergoing AHA surgery were consecutively enrolled from a university hospital in Denmark...
December 1, 2017: Canadian Journal of Surgery. Journal Canadien de Chirurgie
https://www.readbyqxmd.com/read/29161204/effect-of-neoadjuvant-chemoradiotherapy-on-health-related-quality-of-life-in-esophageal-or-junctional-cancer-results-from-the-randomized-cross-trial
#13
Bo Jan Noordman, Mathilde G E Verdam, Sjoerd M Lagarde, Maarten C C M Hulshof, Pieter van Hagen, Mark I van Berge Henegouwen, Bas P L Wijnhoven, Hanneke W M van Laarhoven, Grard A P Nieuwenhuijzen, Geke A P Hospers, Johannes J Bonenkamp, Miguel A Cuesta, Reinoud J B Blaisse, Olivier R Busch, Fiebo J W Ten Kate, Geert-Jan M Creemers, Cornelis J A Punt, John Th M Plukker, Henk M W Verheul, Ernst J Spillenaar Bilgen, Herman van Dekken, Maurice J C van der Sangen, Tom Rozema, Katharina Biermann, Jannet C Beukema, Anna H M Piet, Caroline M van Rij, Janny G Reinders, Hugo W Tilanus, Ewout W Steyerberg, Ate van der Gaast, Mirjam A G Sprangers, J Jan B van Lanschot
Purpose To compare pre-agreed health-related quality of life (HRQOL) domains in patients with esophageal or junctional cancer who received neoadjuvant chemoradiotherapy (nCRT) followed by surgery or surgery alone. Secondary aims were to examine the effect of nCRT on HRQOL before surgery and the effect of surgery on HRQOL. Patients and Methods Patients were randomly assigned to nCRT (carboplatin plus paclitaxel with concurrent 41.4-Gy radiotherapy) followed by surgery or surgery alone. HRQOL was measured using the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (QLQ-C30) and -Oesophageal Cancer Module (QLQ-OES24) questionnaires pretreatment and at 3, 6, 9, and 12 months postoperatively...
November 21, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29159738/prospective-assessment-of-first-year-quality-of-life-after-pelvic-exenteration-for-gynecologic-malignancy-a-french-multicentric-study
#14
A Martinez, T Filleron, P Rouanet, P Méeus, E Lambaudie, J M Classe, F Foucher, F Narducci, S Gouy, F Guyon, F Marchal, E Jouve, P E Colombo, A Mourregot, M Rivoire, N Chopin, G Houvenaeghel, I Jaffre, J Leveque, V Lavoue, E Leblanc, P Morice, E Stoeckle, J L Verheaghe, D Querleu, G Ferron
BACKGROUND: Pelvic exenteration remains one of the most mutilating procedures, with important postoperative morbidity, an altered body image, and long-term physical and psychosocial concerns. This study aimed to assess quality of life (QOL) during the first year after pelvic exenteration for gynecologic malignancy performed with curative intent. METHODS: A French multicentric prospective study was performed by including patients who underwent pelvic exenteration...
November 20, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29157765/the-effect-of-preoperative-oral-carbohydrate-solution-intake-on-patient-comfort-a-randomized-controlled-study
#15
Emel Çakar, Emel Yilmaz, Ekrem Çakar, Hakan Baydur
PURPOSE: The study was conducted to investigate the effect of preoperative oral carbohydrate loading on the preoperative discomforts and postoperative complications of patients undergoing elective thyroidectomy. DESIGN: A randomized controlled clinical trial. METHODS: Ninety patients scheduled for thyroidectomy were divided into three groups: (1) those receiving a carbohydrate-rich drink (CHD), (2) those receiving an overnight 5% glucose intravenous infusion, and (3) those fasting from midnight...
December 2017: Journal of Perianesthesia Nursing: Official Journal of the American Society of PeriAnesthesia Nurses
https://www.readbyqxmd.com/read/29135590/the-analgesic-effect-of-ultrasound-guided-quadratus-lumborum-block-after-cesarean-delivery-a-randomized-clinical-trial
#16
Anders Krohg, Kyrre Ullensvang, Leiv Arne Rosseland, Eldrid Langesæter, Axel R Sauter
BACKGROUND: Landmark and ultrasound-guided transversus abdominis plane blocks have demonstrated an opioid-sparing effect postoperatively after cesarean delivery. The more posterior quadratus lumborum (QL) might provide superior local anesthetic spread to the thoracolumbar fascia and paravertebral space. The aim of our study was to evaluate the efficacy of the QL block after cesarean delivery. METHODS: A randomized, double-blind, controlled trial was performed. Forty parturients undergoing cesarean delivery received bilateral ultrasound-guided QL blocks with either 2 mg/mL ropivacaine or saline postoperatively...
November 10, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29126244/impact-of-neoadjuvant-chemoradiotherapy-on-health-related-quality-of-life-in-long-term-survivors-of-esophageal-or-junctional-cancer-results-from-the-randomized-cross-trial
#17
B J Noordman, M G E Verdam, S M Lagarde, J Shapiro, M C C M Hulshof, M I van Berge Henegouwen, B P L Wijnhoven, G A P Nieuwenhuijzen, J J Bonenkamp, M A Cuesta, J Th M Plukker, E J Spillenaar Bilgen, E W Steyerberg, A van der Gaast, M A G Sprangers, J J B van Lanschot
Background: Neoadjuvant chemoradiotherapy (nCRT) plus surgery is a standard of care for patients with esophageal or junctional cancer, but the long-term impact of nCRT on health-related quality of life (HRQOL) is unknown. The purpose of this study is to compare very long-term HRQOL in long-term survivors of esophageal cancer who received nCRT plus surgery or surgery alone. Patients and methods: Patients were randomly assigned to receive nCRT (carboplatin/paclitaxel with 41...
November 6, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/29118985/acute-development-of-cushing-syndrome-in-an-hiv-infected-child-on-atazanavir-ritonavir-based-antiretroviral-therapy
#18
Gueorgui Dubrocq, Andrea Estrada, Shannon Kelly, Natella Rakhmanina
An 11-year-old male with perinatally acquired human immune deficiency virus (HIV) infection on antiretroviral regimen, which included abacavir plus lamivudine (Epzicom), didanosine, ritonavir and atazanavir presented with bilateral axillary striae, increased appetite, fatigue, facial swelling and acute weight gain. Two months prior to presentation, the patient had received a diagnostic and therapeutic intra-articular triamcinolone injection in the knee for pain relief and subsequently became progressively swollen in the face, developed striae bilaterally at the axillae, experienced increased appetite, fatigue and an 8 pound weight gain...
2017: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/29111887/use-of-short-message-service-and-smartphone-applications-in-the-management-of-surgical-patients-a-systematic-review
#19
Keyin Lu, Nikolas E Marino, David Russell, Aashray Singareddy, Donald Zhang, Angela Hardi, Scott Kaar, Varun Puri
BACKGROUND: Mobile health and telemedicine are rapidly evolving fields used to provide healthcare remotely to patients. For surgical patients, telemedicine can improve patient education and remote monitoring of postoperative symptoms. We performed a systematic review of studies involving the use of short message service (SMS) and mobile application-based interventions in surgical patients to evaluate the advantages and disadvantages of each system, as well as of mobile interventions as a whole...
November 7, 2017: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/29108318/intraoperative-use-of-dexmedetomidine-promotes-postoperative-sleep-and-recovery-following-radical-mastectomy-under-general-anesthesia
#20
Cunxian Shi, Jin Jin, Qiang Pan, Shan Song, Kezhong Li, Jiahai Ma, Tao Li, Zhi Li
Postoperative sleep disturbance and fatigue following radical mastectomy were high risks for prolonged convalescence in patients with breast cancer. The present study was designed to observe the effect of intraoperative use of dexmedetomidine on postoperative sleep, fatigue and recovery following radical mastectomy under general anesthesia. Forty-seven patients were randomized into two groups that were maintained with propofol/remifentanil/Ringer's solution (Control group), or propofol/remifentanil/Dexmedetomidine (DEX group) for surgery under general anesthesia...
October 3, 2017: Oncotarget
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