Read by QxMD icon Read

Janak Shah

Rabindra R Watson, Jason Klapman, Srinadh Komanduri, Janak N Shah, Sachin Wani, Raman Muthusamy
BACKGROUND: Sphincter of Oddi manometry (SOM) is recommended in the evaluation of suspected Type II sphincter of Oddi dysfunction (SOD2), though its utility is uncertain. Little is known about the practice of expert endoscopists in the United States regarding SOD2. METHODS: An anonymous electronic survey was distributed to 128 expert biliary endoscopists identified from U.S. advanced endoscopy training programs. RESULTS: The response rate was 46...
September 2016: Endoscopy International Open
Karan M Shah, Matt M Stern, Amber R Stern, Janak L Pathak, Nathalie Bravenboer, Astrid D Bakker
The aim of this paper is to present several popular methods for in vitro culture of osteocytes and osteocyte cell lines. Osteocytes are located extremely suitably within the calcified bone matrix to sense mechanical signals, and are equipped with a multitude of molecular features that allow mechanosensing. However, osteocytes are more than specialized mechanosensing cells. Several signaling molecules are preferentially produced by osteocytes, and osteocytes hold a tight reign over osteoblast and osteoclast formation and activity, but also have a role as endocrine cell, communicating with muscles or organs as remote as the kidneys...
2016: BoneKEy Reports
A Aziz Aadam, Sachin Wani, Ashley Amick, Janak N Shah, Yasser M Bhat, Christopher M Hamerski, Jason B Klapman, V Raman Muthusamy, Rabindra R Watson, Alfred W Rademaker, Rajesh N Keswani, Laurie Keefer, Ananya Das, Srinadh Komanduri
BACKGROUND AND STUDY AIMS: Techniques to optimize endoscopic ultrasound-guided tissue acquisition (EUS-TA) in a variety of lesion types have not yet been established. The primary aim of this study was to compare the diagnostic yield (DY) of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) to endoscopic ultrasound-guided fine needle biopsy (EUS-FNB) for pancreatic and non-pancreatic masses. PATIENTS AND METHODS: Consecutive patients referred for EUS-TA underwent randomization to EUS-FNA or EUS-FNB at four tertiary-care medical centers...
May 2016: Endoscopy International Open
Janak N Shah, Yasser M Bhat, Chris M Hamerski, Steve D Kane, Kenneth F Binmoeller
BACKGROUND AND AIMS: ERCP inherently involves radiation exposure. Nonradiation ERCP has been described in pregnancy. Theoretically, the same techniques could be applied to the general population. We prospectively assessed the feasibility of nonradiation, EUS-based ERCP in nonpregnant patients with choledocholithiasis. METHODS: Consecutive patients referred for ERCP for choledocholithiasis were recruited over a 1-year period. Patients providing study consent underwent the following procedural protocol...
March 31, 2016: Gastrointestinal Endoscopy
Amy Tyberg, Manuel Perez-Miranda, Ramon Sanchez-Ocaña, Irene Peñas, Carlos de la Serna, Janak Shah, Kenneth Binmoeller, Monica Gaidhane, Ian Grimm, Todd Baron, Michel Kahaleh
BACKGROUND: Surgical gastrojejunostomy and enteral self-expanding metal stents are efficacious for the management of gastric outlet obstruction but limited by high complication rates and short-term efficacy. Endoscopic ultrasound-guided gastrojejunostomy (EUS-GJ) is a novel alternative option. PATIENTS AND METHODS: Patients who underwent EUS-GJ between March 2014 and September 2015 as part of a prospective multicenter registry at four academic centers in two countries were included...
March 2016: Endoscopy International Open
Praneet Korrapati, Jody Ciolino, Sachin Wani, Janak Shah, Rabindra Watson, V Raman Muthusamy, Jason Klapman, Srinadh Komanduri
BACKGROUND AND STUDY AIMS: Current evidence supporting the efficacy of peroral cholangioscopy (POC) in the evaluation and management of difficult bile duct stones and indeterminate strictures is limited. The aims of this systematic review and meta-analysis were to assess the following: the efficacy of POC for the therapy of difficult bile duct stones, the diagnostic accuracy of POC for the evaluation of indeterminate biliary strictures, and the overall adverse event rates for POC. PATIENTS AND METHODS: Patients referred for the removal of difficult bile duct stones or the evaluation of indeterminate strictures via POC were included...
March 2016: Endoscopy International Open
Ryan Law, Ananya Das, Dyanna Gregory, Srinadh Komanduri, Raman Muthusamy, Amit Rastogi, John Vargo, Michael B Wallace, G S Raju, Rawad Mounzer, Jason Klapman, Janak Shah, Rabindra Watson, Robert Wilson, Steven A Edmundowicz, Sachin Wani
BACKGROUND AND AIMS: Endoscopic resection (ER) is an efficacious treatment for complex colon polyps (CCPs). Many patients are referred for surgical resection because of concerns over procedural safety, incomplete polyp resection, and adenoma recurrence after ER. Efficacy data for both resection strategies are widely available, but a paucity of data exist on the cost-effectiveness of each modality. The aim of this study was to perform an economic analysis comparing ER and laparoscopic resection (LR) strategies in patients with CCP...
June 2016: Gastrointestinal Endoscopy
Yasser M Bhat, Frank Weilert, R Todd Fredrick, Steven D Kane, Janak N Shah, Chris M Hamerski, Kenneth F Binmoeller
BACKGROUND AND AIMS: Conventional endoscopic treatment of gastric fundal varices (GFV) with cyanoacrylate (CYA) glue may be complicated by embolization and rebleeding. We evaluated the long-term outcomes of EUS-guided injection of coils and CYA glue for therapy of GFV. METHODS: A retrospective chart review of patients treated for GFV was performed. The main outcomes measured were hemostasis, obliteration on surveillance EUS, post-treatment bleeding rate, and adverse events...
June 2016: Gastrointestinal Endoscopy
Kenneth F Binmoeller, Chris M Hamerski, Janak N Shah, Yasser M Bhat, Steven D Kane
BACKGROUND AND AIMS: EMR of adenomas involving the appendiceal orifice (AO) is controversial because of a high risk of perforation and incomplete resection. We evaluated the feasibility, safety, and outcomes of underwater EMR (UEMR) without submucosal injection for the treatment of adenomas involving the AO. METHODS: This was a prospective, observational study of a standardized UEMR technique without submucosal injection for adenomas involving the AO in 27 consecutive patients meeting inclusion and exclusion criteria...
March 2016: Gastrointestinal Endoscopy
Amandeep K Shergill, Erin E Conners, Kenneth R McQuaid, Sara Epstein, James C Ryan, Janak N Shah, John Inadomi, Ma Somsouk
BACKGROUND: The protective effect of colonoscopy against proximal colorectal cancer is variable and depends on the detection and complete removal of precancerous polyps. OBJECTIVE: To estimate the efficacy of colonoscopy in a medical center with open-access screening colonoscopy since 1998. DESIGN: Nested case-control study with incidence density sampling. SETTING: University-affiliated Veterans Affairs Medical Center...
September 2015: Gastrointestinal Endoscopy
Kenneth F Binmoeller, Christopher M Hamerski, Janak N Shah, Yasser M Bhat, Steven D Kane, Richard Garcia-Kennedy
OBJECTIVE: To evaluate the feasibility and outcomes of attempted underwater en bloc resection (UEBR) of large colorectal laterally spreading tumors (LSTs). DESIGN: Prospective, observational study. SETTING: Tertiary academic referral center. PATIENTS: Fifty patients meeting the inclusion and exclusion criteria. INTERVENTIONS: Standardized UEBR technique involving attempted en bloc resection without submucosal injection by using a large 33-mm snare...
March 2015: Gastrointestinal Endoscopy
Phillip S Ge, Christopher M Hamerski, Rabindra R Watson, Srinadh Komanduri, Birtukan B Cinnor, Kiran Bidari, Jason B Klapman, Cui L Lin, Janak N Shah, Sachin Wani, Timothy R Donahue, V Raman Muthusamy
BACKGROUND: Plastic stents in patients with biliary obstruction caused by pancreatic adenocarcinoma are typically exchanged at 3-month intervals. Plastic stents may have reduced durability in patients receiving chemotherapy. OBJECTIVE: To determine the duration of plastic biliary stent patency in patients undergoing chemotherapy for pancreatic adenocarcinoma. DESIGN: Retrospective, multicenter cohort study. SETTING: Three tertiary academic referral centers...
February 2015: Gastrointestinal Endoscopy
Raj J Shah, Janak N Shah, Irving Waxman, Thomas E Kowalski, Andres Sanchez-Yague, Jose Nieto, Brian C Brauer, Monica Gaidhane, Michel Kahaleh
BACKGROUND & AIMS: Plastic stents, placed via endoscopy to drain pancreatic fluid collections (PFCs), require repeat access. Covered metal stents are larger in diameter and can be inserted in a single step, but can migrate. We evaluated the safety and efficacy of a lumen-apposing, covered, self-expanding metal stent (LACSEMS) for PFC drainage. METHODS: We performed a prospective study of the outcomes of stent placement in 33 patients (18 men; age, 53 ± 14 y; 28 with chronic pancreatitis) with symptomatic pancreatic pseudocysts and walled-off necrosis (≥ 6 cm with ≥ 70% fluid content)...
April 2015: Clinical Gastroenterology and Hepatology
Yasser M Bhat, Steve D Kane, Janak N Shah, Chris M Hamerski, Kenneth F Binmoeller
No abstract text is available yet for this article.
August 2014: Gastrointestinal Endoscopy
Frank Weilert, Yasser M Bhat, Kenneth F Binmoeller, Steve Kane, Ian M Jaffee, Richard E Shaw, Rees Cameron, Yusuke Hashimoto, Janak N Shah
BACKGROUND: Both EUS and ERCP sampling techniques may provide tissue diagnoses in suspected malignant biliary obstruction. However, there are scant data comparing these 2 methods. OBJECTIVE: To compare EUS-guided FNA (EUS-FNA) and ERCP tissue sampling for the diagnosis of malignant biliary obstruction. DESIGN: Prospective, comparative, single-blind study. SETTING: Tertiary center. PATIENTS: Fifty-one patients undergoing same-session EUS and ERCP for the evaluation of malignant biliary obstruction over a 1-year period...
July 2014: Gastrointestinal Endoscopy
Kenneth F Binmoeller, Janak N Shah, Yasser M Bhat, Steve D Kane
BACKGROUND: The diagnosis and therapy of subepithelial tumors (SETs) can be challenging. OBJECTIVE: Proof-of-concept evaluation of the suck-ligate-unroof-biopsy (SLUB) technique for small (<2 cm), non-pedunculated SETs. DESIGN: Pilot feasibility study. SETTING: Tertiary-care referral center. PATIENTS: Twenty-three patients (median age 60 years) meeting the inclusion criteria after preliminary EUS...
May 2014: Gastrointestinal Endoscopy
Sheba Vohra, Edward W Holt, Yasser M Bhat, Steve Kane, Janak N Shah, Kenneth F Binmoeller
PURPOSE: Same session endosonography (EUS) immediately prior to scheduled endoscopic retrograde cholangiopancreatography (ERCP) may eliminate the need for ERCP and its associated risks in pregnant patients with no evidence of choledocholithiasis on EUS. In patients with choledocholithiasis, EUS provides information regarding the location, size and number of stones present, which helps guide biliary interventions and confirm stone clearance without the use of fluoroscopy. METHODS: We retrospectively identified 10 pregnant patients referred to our tertiary endoscopy center for suspected choledocholithiasis between June 2008 and January 2012...
February 2014: Journal of Hepato-biliary-pancreatic Sciences
Kenneth F Binmoeller, Janak N Shah, Yasser M Bhat, Steve D Kane
BACKGROUND: EMR for the treatment of duodenal adenomas is challenging due to a thin wall and rich vascularity. OBJECTIVE: To evaluate a novel technique of "underwater" EMR without prior submucosal injection for the removal of large (≥2 cm) laterally spreading nonampullary duodenal adenomas. DESIGN: Prospective, observational study. SETTING: Tertiary academic referral center. PATIENTS: Twelve patients (median age, 60 years) meeting the inclusion criteria...
September 2013: Gastrointestinal Endoscopy
Alexander Lee, Janak N Shah
Endoscopic retrograde cholangiopancreatography (ERCP) in surgically altered anatomy can be technically challenging, because of three main problems that must be overcome: (1) endoscopically traversing the altered luminal anatomy, (2) cannulating the biliary orifice from an altered position, and (3) performing biliary interventions with available ERCP instruments. This article addresses the most common and most challenging variations in anatomy encountered by a gastroenterologist performing ERCP. It also highlights the innovations and progress that have been made in coping with these anatomic variations, with special attention paid to altered anatomy from bariatric surgery...
April 2013: Gastrointestinal Endoscopy Clinics of North America
Kenneth F Binmoeller, Janak N Shah, Yasser M Bhat, Steve D Kane
BACKGROUND: We report a novel technique of retract-ligate-unroof-biopsy (RLUB) for the diagnosis and treatment of large nonpedunculated upper GI stromal tumors originating from the muscularis propria. OBJECTIVE: Proof-of-concept evaluation of the RLUB technique. DESIGN: Pilot and feasibility study. SETTING: Tertiary care center. PATIENTS: Sixteen patients (median age 71 years) fulfilling the following inclusion criteria: poor surgical candidates with lesions that are broad based with a benign appearance, originating from the muscularis propria, size 2 cm or larger...
May 2013: Gastrointestinal Endoscopy
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"