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Mark Topazian

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https://www.readbyqxmd.com/read/28926412/endoscopic-ultrasound-and-related-technologies-for-the-diagnosis-and-treatment-of-pancreatic-disease-research-gaps-and-opportunities-summary-of-a-national-institute-of-diabetes-and-digestive-and-kidney-diseases-workshop
#1
Linda S Lee, Dana K Andersen, Reiko Ashida, William R Brugge, Mimi I Canto, Kenneth J Chang, Suresh T Chari, John DeWitt, Joo Ha Hwang, Mouen A Khashab, Kang Kim, Michael J Levy, Kevin McGrath, Walter G Park, Aatur Singhi, Tyler Stevens, Christopher C Thompson, Mark D Topazian, Michael B Wallace, Sachin Wani, Irving Waxman, Dhiraj Yadav, Vikesh K Singh
A workshop was sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases to address the research gaps and opportunities in pancreatic endoscopic ultrasound (EUS). The event occurred on July 26, 2017 in 4 sessions: (1) benign pancreatic diseases, (2) high-risk pancreatic diseases, (3) diagnostic and therapeutics, and (4) new technologies. The current state of knowledge was reviewed, with identification of numerous gaps in knowledge and research needs. Common themes included the need for large multicenter consortia of various pancreatic diseases to facilitate meaningful research of these entities; to standardize EUS features of different pancreatic disorders, the technique of sampling pancreatic lesions, and the performance of various therapeutic EUS procedures; and to identify high-risk disease early at the cellular level before macroscopic disease develops...
September 18, 2017: Pancreas
https://www.readbyqxmd.com/read/28924591/safety-and-efficacy-of-coaxial-lumen-apposing-metal-stents-in-the-management-of-refractory-gastrointestinal-luminal-strictures-a-multicenter-study
#2
Fateh Bazerbachi, Jason D Heffley, Barham K Abu Dayyeh, Jose Nieto, Eric J Vargas, Tarek Sawas, Raja Zaghlol, Navtej S Buttar, Mark D Topazian, Louis M Wong Kee Song, Michael Levy, Steve Keilin, Qiang Cai, Field F Willingham
BACKGROUND AND AIMS:  Benign gastrointestinal (GI) strictures are often refractory to standard endoscopic interventions. Fully covered coaxial lumen-apposing metal stents (LAMS) have emerged as a novel therapy for these strictures. The aim of this study was to evaluate the safety and efficacy of LAMS for refractory GI strictures. PATIENTS AND METHODS:  A retrospective analysis was performed for patients who underwent LAMS placement for benign luminal strictures in three US centers between January 2014 and December 2016...
September 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28867073/metal-stents-versus-plastic-stents-for-the-management-of-pancreatic-walled-off-necrosis-a-systematic-review-and-meta-analysis
#3
REVIEW
Fateh Bazerbachi, Tarek Sawas, Eric J Vargas, Larry J Prokop, Suresh T Chari, Ferga C Gleeson, Michael J Levy, John Martin, Bret T Petersen, Randall K Pearson, Mark D Topazian, Santhi S Vege, Barham K Abu Dayyeh
BACKGROUND AND AIMS: Endoscopic transluminal drainage of symptomatic walled-off necrosis (WON) is a good management option, although the optimal choice of drainage site stent is unclear. We performed a systematic review and meta-analysis to compare metal stents (MSs) and plastic stents (PSs) in terms of WON resolution, likelihood of resolution after one procedure, and adverse events. METHODS: An expert librarian queried several databases to identify studies that assessed WON management, and selection was according to a priori criteria...
August 31, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28753701/reprocessing-of-single-use-endoscopic-variceal-band-ligation-devices-a-pilot-study
#4
Kavel Visrodia, Abdul Haseeb, Yuri Hanada, Kelly M Pennington, Magdalen Clemens, Paul J Pearce, Pritish K Tosh, Bret T Petersen, Mark D Topazian
Background and study aims The preferred management of bleeding esophageal varices includes endoscopic band ligation. Endoscopic ligation devices (ELDs) are expensive and designed for single use, limiting their uptake in developing countries. We aimed to assess the efficacy of reprocessing ELDs using terminal microbial cultures and adenosine triphosphate (ATP) testing. Materials and methods ELDs were recovered after clinical use and their components (cap, handle, and cord) were subjected to reprocessing...
July 28, 2017: Endoscopy
https://www.readbyqxmd.com/read/28697145/carbon-dioxide-insufflation-during-endoscopic-pancreatic-function-tests-does-not-alter-duodenal-aspirate-bicarbonate-concentrations
#5
Sonmoon Mohapatra, Shounak Majumder, Barham K Abu Dayyeh, Suresh T Chari, Ferga Gleeson, Prasad G Iyer, Michael J Levy, Randall K Pearson, Bret T Petersen, Santhi S Vege, Mark Topazian
No abstract text is available yet for this article.
August 2017: Pancreas
https://www.readbyqxmd.com/read/28664438/transoral-outlet-reduction-with-full-thickness-endoscopic-suturing-for-weight-regain-after-gastric-bypass-a-large-multicenter-international-experience-and-meta-analysis
#6
Eric J Vargas, Fateh Bazerbachi, Monika Rizk, Tarun Rustagi, Andres Acosta, Erik B Wilson, Todd Wilson, Manoel Galvao Neto, Natan Zundel, Manpreet S Mundi, Maria L Collazo-Clavell, Shah Meera, H S Abu-Lebdeh, Paul A Lorentz, Karen B Grothe, Matthew M Clark, Todd A Kellogg, Travis J McKenzie, Michael L Kendrick, Mark D Topazian, Christopher J Gostout, Barham K Abu Dayyeh
BACKGROUND AND AIMS: Many patients who undergo bariatric surgery will experience weight regain and effective strategies are needed to help these patients. A dilated gastrojejunal anastomosis (GJA) has been associated with weight recidivism after Roux-en-Y gastric bypass surgery (RYGB). Endoscopic transoral outlet reduction (TORe) with a full thickness endoscopic suturing device (Overstitch, Apollo Endosurgery, Austin, TX) is a minimally invasive therapeutic option. The primary aim of this project was to examine the safety and long-term efficacy data from three bariatric surgery centers and to conduct a systematic review and meta-analysis of the existing literature...
June 29, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28491925/no-camphor-toxicity-in-cambodian-infants
#7
Casey R Johnson, Samuel G Porter, Debra Coats, Kyly C Whitfield, Khin Mengkheang, Mark D Topazian, Philip R Fischer
Thiamine deficiency and beriberi are prevalent in Cambodia, although most infants with nonspecific clinical symptoms of beriberi, including tachypnea, lack echocardiographic evidence diagnostic of the disease. Camphor activates transient receptor potential vanilloid 3 (TRPV3), a nonselective ion channel expressed in the medial preoptic nucleus of the hypothalamus and thought to be important for thermo-sensitivity. Because camphorated ointments are used commonly among Cambodian infants, we hypothesized that topical camphor modulates thermoregulatory behaviors, causing beriberi-simulating tachypnea, separate from any influence of thiamine deficiency...
2017: Global Pediatric Health
https://www.readbyqxmd.com/read/28451929/endoscopic-sleeve-gastroplasty-for-obesity-a-multicenter-study-of-248-patients-with-24%C3%A2-months-follow-up
#8
Gontrand Lopez-Nava, Reem Z Sharaiha, Eric J Vargas, Fateh Bazerbachi, Galvao Neto Manoel, Inmaculada Bautista-Castaño, Andres Acosta, Mark D Topazian, Manpreet S Mundi, Nikhil Kumta, Michel Kahaleh, Andrea Marie Herr, Alpana Shukla, Louis Aronne, Christopher J Gostout, Barham K Abu Dayyeh
BACKGROUND: Endoscopic sleeve gastroplasty (ESG) is a technique for managing mild to moderately obese patients. We aimed to evaluate the long-term outcomes, reproducibility, and predictors of weight response in a large multicenter cohort. METHODS: Patients who underwent ESG between January 2013 and December 2015 in three centers were retrospectively analyzed. All procedures were performed using the Apollo OverStitch device (Apollo Endosurgery, Austin, TX). We performed per protocol (PP) and intention-to-treat (ITT) analyses, where patients lost to follow-up were considered failures...
April 27, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28448071/azathioprine-maintenance-therapy-to-prevent-relapses-in-autoimmune-pancreatitis
#9
Nicolò de Pretis, Antonio Amodio, Laura Bernardoni, Pietro Campagnola, Fabiana Capuano, Suresh T Chari, Stefano Crinò, Armando Gabbrielli, Arianna Massella, Mark Topazian, Luca Frulloni
OBJECTIVES: Steroids are used to induce remission in autoimmune pancreatitis (AIP). Low-dosage steroid therapy or immunosuppressant (IMs) has been proposed as maintenance therapy to prevent AIP relapse. Few and conflicting data have been published on the efficacy of azathioprine (AZA) in preventing AIP relapse. The aim of this study was to evaluate the indication and efficacy of AZA as maintenance therapy to prevent disease relapse in AIP. METHODS: Patients suffering from AIP diagnosed according to the ICDC in type 1, type 2, and not otherwise specified (NOS) were divided in those treated with AZA (AZA(+) group) as maintenance therapy and not treated with maintenance therapy (AZA(-) group)...
April 27, 2017: Clinical and Translational Gastroenterology
https://www.readbyqxmd.com/read/28403980/characteristics-management-and-outcomes-of-patients-with-hepatocellular-carcinoma-in-africa-a-multicountry-observational-study-from-the-africa-liver-cancer-consortium
#10
Ju Dong Yang, Essa A Mohamed, Ashraf O Abdel Aziz, Hend I Shousha, Mohamed B Hashem, Mohamed M Nabeel, Ahmed H Abdelmaksoud, Tamer M Elbaz, Mary Y Afihene, Babatunde M Duduyemi, Joshua P Ayawin, Adam Gyedu, Marie-Jeanne Lohouès-Kouacou, Antonin W Ndjitoyap Ndam, Ehab F Moustafa, Sahar M Hassany, Abdelmajeed M Moussa, Rose A Ugiagbe, Casimir E Omuemu, Richard Anthony, Dennis Palmer, Albert F Nyanga, Abraham O Malu, Solomon Obekpa, Abdelmounem E Abdo, Awatif I Siddig, Hatim M Y Mudawi, Uchenna Okonkwo, Mbang Kooffreh-Ada, Yaw A Awuku, Yvonne A Nartey, Elizabeth T Abbew, Nana A Awuku, Jesse A Otegbayo, Kolawole O Akande, Hailemichael M Desalegn, Abidemi E Omonisi, Akande O Ajayi, Edith N Okeke, Mary J Duguru, Pantong M Davwar, Michael C Okorie, Shettima Mustapha, Jose D Debes, Ponsiano Ocama, Olufunmilayo A Lesi, Emuobor Odeghe, Ruth Bello, Charles Onyekwere, Francis Ekere, Rufina Igetei, Mitchell A Mah'moud, Benyam Addissie, Hawa M Ali, Gregory J Gores, Mark D Topazian, Lewis R Roberts
BACKGROUND: Hepatocellular carcinoma is a leading cause of cancer-related death in Africa, but there is still no comprehensive description of the current status of its epidemiology in Africa. We therefore initiated an African hepatocellular carcinoma consortium aiming to describe the clinical presentation, management, and outcomes of patients with hepatocellular carcinoma in Africa. METHODS: We did a multicentre, multicountry, retrospective observational cohort study, inviting investigators from the African Network for Gastrointestinal and Liver Diseases to participate in the consortium to develop hepatocellular carcinoma research databases and biospecimen repositories...
February 2017: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28396277/duodenoscope-reprocessing-surveillance-with-adenosine-triphosphate-testing-and-terminal-cultures-a-clinical-pilot-study
#11
Kavel Visrodia, Yuri Hanada, Kelly M Pennington, Pritish K Tosh, Mark D Topazian, Bret T Petersen
BACKGROUND AND AIMS: Recent reports of infectious outbreaks linked to duodenoscopes have led to proposals for duodenoscope surveillance culturing, which has inherent limitations. We aimed to assess the feasibility of real-time adenosine triphosphate (ATP) testing after manual cleaning and its ability to predict reprocessing adequacy, as determined by terminal duodenoscope cultures. METHODS: Clinically used duodenoscopes underwent reprocessing per current guidelines...
July 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28342894/endoscopic-treatment-of-cervical-esophageal-transluminal-bridge
#12
Sinkeet Ranketi, Michael Mwachiro, Mark Topazian, Stephen Burgert
No abstract text is available yet for this article.
March 22, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28263238/evaluation-of-effects-of-radiofrequency-ablation-of-ex-vivo-liver-using-the-1-fr-wire-electrode
#13
Tarun Rustagi, Ferga C Gleeson, Barham K Abu Dayyeh, Mark D Topazian, Michael J Levy
BACKGROUND AND STUDY AIMS: Percutaneous and intraoperative radiofrequency ablation (RFA) has become a valued tool in the management of primary and secondary hepatic lesions. A recent FDA-approved endoscopic ultrasound (EUS)-guided RFA probe now offers promise to help manage such lesions. However, there are no data to determine the ideal power setting and duration of ablation needed to effectively treat hepatic masses. The aim of the study was to evaluate the macroscopic zone of hepatic injury for EUS-RFA using a variety of settings within a fresh porcine hepatic specimen...
March 3, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28043931/similar-efficacies-of-endoscopic-ultrasound-gallbladder-drainage-with-a-lumen-apposing-metal-stent-versus-percutaneous-transhepatic-gallbladder-drainage-for-acute%C3%A2-cholecystitis
#14
Shayan Irani, Saowanee Ngamruengphong, Anthony Teoh, Uwe Will, Jose Nieto, Barham K Abu Dayyeh, S Ian Gan, Michael Larsen, Hon Chi Yip, Mark D Topazian, Michael J Levy, Christopher C Thompson, Andrew C Storm, Gulara Hajiyeva, Amr Ismail, Yen-I Chen, Majidah Bukhari, Yamile Haito Chavez, Vivek Kumbhari, Mouen A Khashab
BACKGROUND & AIMS: Acute cholecystitis in patients who are not candidates for surgery is often managed with percutaneous transhepatic gallbladder drainage (PT-GBD). Endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) with a lumen-apposing metal stent (LAMS) is an effective alternative to PT-GBD. We compared the technical success of EUS-GBD versus PT-GBD, and patient outcomes, numbers of adverse events (AEs), length of hospital stay, pain scores, and repeat interventions. METHODS: We performed a retrospective study to compare EUS-GBD versus PT-GBD at 7 centers (5 in the United States, 1 in Europe, and 1 in Asia), from 2013 through 2015, in management of acute cholecystitis in patients who are not candidates for surgery...
May 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27866907/radiofrequency-ablation-for-intraductal-extension-of-ampullary%C3%A2-neoplasms
#15
Tarun Rustagi, Shayan Irani, D Nageshwar Reddy, Barham K Abu Dayyeh, Todd H Baron, Christopher J Gostout, Michael J Levy, John Martin, Bret T Petersen, Andrew Ross, Mark D Topazian
BACKGROUND AND AIMS: Extension of ampullary adenomas into the common bile duct (CBD) or pancreatic duct (PD) may be difficult to treat endoscopically. We evaluated the feasibility, safety, and efficacy of endoscopic radiofrequency ablation (RFA) in the management of ampullary neoplasms with intraductal extension. METHODS: This was a multicenter, retrospective analysis of all patients with intraductal extension of ampullary neoplasms treated with endoscopic RFA between February 2012 and June 2015...
November 17, 2016: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/27824640/esophagorespiratory-fistulas-survival-and-outcomes-of-treatment
#16
Charles J Lenz, Benjamin L Bick, David Katzka, Francis C Nichols, Zachary S Depew, Louis M Wong Kee Song, Todd H Baron, Navtej S Buttar, Fabien Maldonado, Felicity T Enders, William S Harmsen, Ross A Dierkhising, Mark D Topazian
GOAL: The purpose of this study was to characterize outcomes of esophagorespiratory fistulas (ERF) by etiology and initial treatment strategy. BACKGROUND: ERF is a morbid condition for which optimal treatment strategies and outcomes are still in evolution. STUDY: Medical records and images were reviewed for all patients diagnosed with ERF at Mayo Clinic in Rochester, MN, between September 1, 2001 and January 1, 2012. Fistulas were classified as malignant or benign...
November 7, 2016: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/27807567/endoscopic-ultrasound-guided-treatment-of-pancreaticocutaneous-fistulas
#17
Abdul Haseeb, Barham K Abu Dayyeh, Michael J Levy, Larissa L Fujii, Randall K Pearson, Suresh T Chari, Ferga C Gleeson, Bret T Peterson, Santhi Swaroop Vege, Mark Topazian
Pancreaticocutaneous fistulas (PCFs) may be refractory to medical therapy or endoscopic retrograde cholangopancreaticography. Four patients underwent endoscopic ultrasound-guided management of refractory PCFs, which were internalized by endoscopic ultrasound-guided transmural puncture of the pancreatic duct (n = 2), fistula tract (n = 1), or both (n = 1), with placement of transmural stents providing internal drainage to the stomach (n = 3) or duodenum (n = 1). Drainage from PCFs ceased in all patients, and all percutaneous drains were removed; internal stents were left in place indefinitely...
August 2016: ACG Case Reports Journal
https://www.readbyqxmd.com/read/27773725/remote-malignant-intravascular-thrombi-eus-guided-fna-diagnosis-and-impact-on-cancer-staging
#18
Tarun Rustagi, Ferga C Gleeson, Suresh T Chari, Barham K Abu Dayyeh, Michael B Farnell, Prasad G Iyer, Michael L Kendrick, Randall K Pearson, Bret T Petersen, Elizabeth Rajan, Mark D Topazian, Mark J Truty, Santhi S Vege, Kenneth K Wang, Michael J Levy
BACKGROUND AND AIMS: Malignant vascular invasion usually results from gross direct infiltration from a primary tumor and impacts cancer staging, prognosis, and therapy. However, patients may also develop a remote malignant thrombi (RMT), defined as a malignant intravascular thrombus located remote and noncontiguous to the primary tumor. Our aim was to compare EUS, CT, and magnetic resonance imaging (MRI) findings of RMT and to explore the potential impact on cancer staging. METHODS: Patients with RMT were identified from a prospectively maintained EUS database...
October 20, 2016: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/27642384/the-spectrum-of-paediatric-intestinal-obstruction-in-kenya
#19
Philip Blasto Ooko, Patricia Wambua, Mark Oloo, Agneta Odera, Hillary Mariko Topazian, Russell White
INTRODUCTION: Intestinal obstruction (IO) occurs when there is impedance to the flow of intestinal contents due to a congenital or acquired pathology, and is a common paediatric surgical emergency. This study aimed to assess the pattern and outcome of paediatric IO in western Kenya. METHODS: A retrospective review of all recorded cases of mechanical IO in patients aged 15 years or below admitted at Tenwek Hospital between January 2009 and December 2013. RESULTS: The cohort included a total of 217 children (130 boys and 87 girls)...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27539084/endoscopic-ultrasound-fine-needle-aspiration-diagnosis-of-synchronous-primary-pancreatic-adenocarcinoma-and-effects-on-staging-and-resectability
#20
Tarun Rustagi, Ferga C Gleeson, Suresh T Chari, Barham K Abu Dayyeh, Michael B Farnell, Prasad G Iyer, Michael L Kendrick, Randall K Pearson, Bret T Petersen, Elizabeth Rajan, Mark D Topazian, Mark J Truty, Santhi S Vege, Kenneth K Wang, Michael J Levy
Synchronous primary pancreatic adenocarcinoma, defined as the simultaneous presence of 2 or more newly identified and anatomically separate primary adenocarcinomas within the pancreas, is reported rarely. We compared endoscopic ultrasound (EUS) and computed tomography (CT) and magnetic resonance imaging (MRI) findings from patients with synchronous primary pancreatic adenocarcinoma and their effects on cancer staging and treatment. We performed a retrospective analysis of the EUS database at the Mayo Clinic, from September 2008 through May 2016, to collect EUS, CT, MRI, and clinical data from patients with synchronous primary pancreatic adenocarcinoma...
February 2017: Clinical Gastroenterology and Hepatology
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