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Mark Topazian

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https://www.readbyqxmd.com/read/29723506/fasting-blood-glucose-levels-provide-estimate-of-duration-and-progression-of-pancreatic-cancer-before-diagnosis
#1
Ayush Sharma, Thomas C Smyrk, Michael J Levy, Mark A Topazian, Suresh T Chari
BACKGROUND & AIMS: It is unclear how long pancreatic ductal adenocarcinomas (PDACs) are present before diagnosis. Patients with PDAC usually develop hyperglycemia and diabetes before the tumor is identified. If early invasive PDACs are associated with hyperglycemia, the duration of hyperglycemia should associate with the time that they have had the tumor. METHODS: We collected data on patients with PDACs from medical databases in Olmsted County, Minnesota from 2000 through 2015 and from the Mayo Clinic's tumor registry, from January 1, 1976 through January 1, 2017...
April 30, 2018: Gastroenterology
https://www.readbyqxmd.com/read/29709526/screening-for-esophageal-squamous-cell-carcinoma-recent-advances
#2
REVIEW
Don C Codipilly, Yi Qin, Sanford M Dawsey, John Kisiel, Mark Topazian, David Ahlquist, Prasad G Iyer
No abstract text is available yet for this article.
April 27, 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29686273/endoscopic-management-of-pancreatic-necrosis
#3
Barham K Abu Dayyeh, Mark Topazian
No abstract text is available yet for this article.
April 24, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29551737/endobariatrics-a-primer
#4
Andrew C Storm, Barham K Abu Dayyeh, Mark Topazian
No abstract text is available yet for this article.
March 15, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29526692/rituximab-maintenance-therapy-reduces-rate-of-relapse-of-pancreaticobiliary-immunoglobulin-g4-related-disease
#5
Shounak Majumder, Sonmoon Mohapatra, Ryan J Lennon, Guilherme Piovezani Ramos, Neil Postier, Ferga C Gleeson, Michael J Levy, Randall K Pearson, Bret T Petersen, Santhi Swaroop Vege, Suresh T Chari, Mark D Topazian, Thomas E Witzig
BACKGROUND & AIMS: IgG4-related disease (IgG4-RD), a multi-organ fibroinflammatory syndrome, typically responds to steroids. However, some cases are steroid resistant, and pancreaticobiliary IgG4-RD commonly relapses after steroid withdrawal. Rituximab induces remission of IgG4-RD, but the need for and safety of maintenance rituximab treatment are unknown. We compared outcomes of patients with pancreaticobiliary IgG4-RD treated with or without maintenance rituximab therapy. METHODS: We performed a retrospective study of patients with pancreaticobiliary IgG4-RD treated with rituximab at the Mayo Clinic in Rochester, Minnesota, from January 2005 through December 2015...
March 8, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29425780/risk-of-pancreatic-cancer-in-patients-with-pancreatic-cysts-and-family-history-of-pancreatic-cancer
#6
Saurabh S Mukewar, Ayush Sharma, Nissy Phillip, Ridhi Gupta, Anupama Aryal-Khanal, Nicolo de Pretis, Vincent Anani, Felicity T Enders, Joseph J Larson, Naoki Takahashi, Michael J Levy, Mark Topazian, Randall K Pearson, Santhi S Vege, Suresh T Chari
BACKGROUND & AIMS: A diagnosis of pancreatic cancer in a first-degree relative increases an individuals' risk of this cancer. However, it is not clear whether this cancer risk increases in individuals with pancreatic cystic lesions who have a first-degree relative with pancreatic cancer. The Fukuoka criteria are used to estimate risk of pancreatic cancer for patients with pancreatic cystic lesions: individuals with cysts with high risk or worrisome features (Fukuoka positive) have a higher risk of pancreatic cancer than individuals without these features (Fukuoka negative)...
February 7, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29223385/mucinous-adenocarcinoma-of-unknown-primary-presenting-with-dysphagia
#7
Sajan Jiv Singh Nagpal, Joanne E Yi, Louis M Wong Kee Song, Mark D Topazian
No abstract text is available yet for this article.
December 6, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29216866/cross-sectional-study-of-serum-selenium-concentration-and-esophageal-squamous-dysplasia-in-western-kenya
#8
Natalie R Pritchett, Stephen L Burgert, Gwen A Murphy, John D Brockman, Russell E White, Justus Lando, Robert Chepkwony, Mark D Topazian, Christian C Abnet, Sanford M Dawsey, Michael M Mwachiro
BACKGROUND: Low serum selenium status has been associated with increased risk of esophageal squamous cell carcinoma (ESCC). East Africa is a region of high ESCC incidence and is known to have low soil selenium levels, but this association has not previously been evaluated. In this study we assessed the association of serum selenium concentration and the prevalence of esophageal squamous dysplasia (ESD), the precursor lesion of ESCC, in a cross-sectional study of subjects from Bomet, Kenya...
December 8, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29074446/efficacy-and-safety-of-digital-single-operator-cholangioscopy-for-difficult-biliary-stones
#9
Olaya I Brewer Gutierrez, Noor L H Bekkali, Isaac Raijman, Richard Sturgess, Divyesh V Sejpal, Hanaa D Aridi, Stuart Sherman, Raj J Shah, Richard S Kwon, James L Buxbaum, Claudio Zulli, Wahid Wassef, Douglas G Adler, Vladimir Kushnir, Andrew Y Wang, Kumar Krishnan, Vivek Kaul, Demetrios Tzimas, Christopher J DiMaio, Sammy Ho, Bret Petersen, Jong Ho Moon, B Joseph Elmunzer, George J M Webster, Yen-I Chen, Laura K Dwyer, Summant Inamdar, Vanessa B Patrick, Augustin Attwell, Amy Hosmer, Christopher Ko, Attilio Maurano, Avik Sarkar, Linda J Taylor, Martin H Gregory, Daniel S Strand, Ali Raza, Shivangi Kothari, Jessica P Harris, Nikhil A Kumta, Amar Manvar, Mark D Topazian, Yun Nah Lee, Clayton M Spiceland, Majidah A Bukhari, Omid Sanaei, Saowanee Ngamruengphong, Mouen A Khashab
BACKGROUND & AIMS: It is not clear whether digital single-operator cholangioscopy (D-SOC) with electrohydraulic and laser lithotripsy is effective in removal of difficult biliary stones. We investigated the safety and efficacy of D-SOC with electrohydraulic and laser lithotripsy in an international, multicenter study of patients with difficult biliary stones. METHODS: We performed a retrospective analysis of 407 patients (60.4% female; mean age, 64.2 years) who underwent D-SOC for difficult biliary stones at 22 tertiary centers in the United States, United Kingdom, or Korea from February 2015 through December 2016; 306 patients underwent electrohydraulic lithotripsy and 101 (24...
October 24, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29024705/management-of-a-circumferential-duodenal-polyp
#10
Andrew C Storm, Mark D Topazian
No abstract text is available yet for this article.
October 10, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28941651/eus-and-related-technologies-for-the-diagnosis-and-treatment-of-pancreatic-disease-research-gaps-and-opportunities-summary-of-a-national-institute-of-diabetes-and-digestive-and-kidney-diseases-workshop
#11
REVIEW
Linda S Lee, Dana K Andersen, Reiko Ashida, William R Brugge, Mimi I Canto, Kenneth J Chang, Suresh T Chari, John DeWitt, Joo Ha Hwang, Mouen A Khashab, Kang Kim, Michael J Levy, Kevin McGrath, Walter G Park, Aatur Singhi, Tyler Stevens, Christopher C Thompson, Mark D Topazian, Michael B Wallace, Sachin Wani, Irving Waxman, Dhiraj Yadav, Vikesh K Singh
A workshop was sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases to address the research gaps and opportunities in pancreatic EUS. The event occurred on July 26, 2017 in 4 sessions: (1) benign pancreatic diseases, (2) high-risk pancreatic diseases, (3) diagnostic and therapeutics, and (4) new technologies. The current state of knowledge was reviewed, with identification of numerous gaps in knowledge and research needs. Common themes included the need for large multicenter consortia of various pancreatic diseases to facilitate meaningful research of these entities; to standardize EUS features of different pancreatic disorders, the technique of sampling pancreatic lesions, and the performance of various therapeutic EUS procedures; and to identify high-risk disease early at the cellular level before macroscopic disease develops...
November 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28926412/endoscopic-ultrasound-and-related-technologies-for-the-diagnosis-and-treatment-of-pancreatic-disease-research-gaps-and-opportunities-summary-of-a-national-institute-of-diabetes-and-digestive-and-kidney-diseases-workshop
#12
Linda S Lee, Dana K Andersen, Reiko Ashida, William R Brugge, Mimi I Canto, Kenneth J Chang, Suresh T Chari, John DeWitt, Joo Ha Hwang, Mouen A Khashab, Kang Kim, Michael J Levy, Kevin McGrath, Walter G Park, Aatur Singhi, Tyler Stevens, Christopher C Thompson, Mark D Topazian, Michael B Wallace, Sachin Wani, Irving Waxman, Dhiraj Yadav, Vikesh K Singh
A workshop was sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases to address the research gaps and opportunities in pancreatic endoscopic ultrasound (EUS). The event occurred on July 26, 2017 in 4 sessions: (1) benign pancreatic diseases, (2) high-risk pancreatic diseases, (3) diagnostic and therapeutics, and (4) new technologies. The current state of knowledge was reviewed, with identification of numerous gaps in knowledge and research needs. Common themes included the need for large multicenter consortia of various pancreatic diseases to facilitate meaningful research of these entities; to standardize EUS features of different pancreatic disorders, the technique of sampling pancreatic lesions, and the performance of various therapeutic EUS procedures; and to identify high-risk disease early at the cellular level before macroscopic disease develops...
November 2017: Pancreas
https://www.readbyqxmd.com/read/28924591/safety-and-efficacy-of-coaxial-lumen-apposing-metal-stents-in-the-management-of-refractory-gastrointestinal-luminal-strictures-a-multicenter-study
#13
Fateh Bazerbachi, Jason D Heffley, Barham K Abu Dayyeh, Jose Nieto, Eric J Vargas, Tarek Sawas, Raja Zaghlol, Navtej S Buttar, Mark D Topazian, Louis M Wong Kee Song, Michael Levy, Steve Keilin, Qiang Cai, Field F Willingham
BACKGROUND AND AIMS:  Benign gastrointestinal (GI) strictures are often refractory to standard endoscopic interventions. Fully covered coaxial lumen-apposing metal stents (LAMS) have emerged as a novel therapy for these strictures. The aim of this study was to evaluate the safety and efficacy of LAMS for refractory GI strictures. PATIENTS AND METHODS:  A retrospective analysis was performed for patients who underwent LAMS placement for benign luminal strictures in three US centers between January 2014 and December 2016...
September 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28867073/metal-stents-versus-plastic-stents-for-the-management-of-pancreatic-walled-off-necrosis-a-systematic-review-and-meta-analysis
#14
REVIEW
Fateh Bazerbachi, Tarek Sawas, Eric J Vargas, Larry J Prokop, Suresh T Chari, Ferga C Gleeson, Michael J Levy, John Martin, Bret T Petersen, Randall K Pearson, Mark D Topazian, Santhi S Vege, Barham K Abu Dayyeh
BACKGROUND AND AIMS: Endoscopic transluminal drainage of symptomatic walled-off necrosis (WON) is a good management option, although the optimal choice of drainage site stent is unclear. We performed a systematic review and meta-analysis to compare metal stents (MSs) and plastic stents (PSs) in terms of WON resolution, likelihood of resolution after 1 procedure, and adverse events. METHODS: An expert librarian queried several databases to identify studies that assessed WON management, and selection was according to a priori criteria...
January 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28753701/reprocessing-of-single-use-endoscopic-variceal-band-ligation-devices-a-pilot-study
#15
Kavel Visrodia, Abdul Haseeb, Yuri Hanada, Kelly M Pennington, Magdalen Clemens, Paul J Pearce, Pritish K Tosh, Bret T Petersen, Mark D Topazian
Background and study aims  The preferred management of bleeding esophageal varices includes endoscopic band ligation. Endoscopic ligation devices (ELDs) are expensive and designed for single use, limiting their uptake in developing countries. We aimed to assess the efficacy of reprocessing ELDs using terminal microbial cultures and adenosine triphosphate (ATP) testing. Materials and methods  ELDs were recovered after clinical use and their components (cap, handle, and cord) were subjected to reprocessing...
December 2017: Endoscopy
https://www.readbyqxmd.com/read/28697145/carbon-dioxide-insufflation-during-endoscopic-pancreatic-function-tests-does-not-alter-duodenal-aspirate-bicarbonate-concentrations
#16
Sonmoon Mohapatra, Shounak Majumder, Barham K Abu Dayyeh, Suresh T Chari, Ferga Gleeson, Prasad G Iyer, Michael J Levy, Randall K Pearson, Bret T Petersen, Santhi S Vege, Mark Topazian
No abstract text is available yet for this article.
August 2017: Pancreas
https://www.readbyqxmd.com/read/28664438/transoral-outlet-reduction-with-full-thickness-endoscopic-suturing-for-weight-regain-after-gastric-bypass-a-large-multicenter-international-experience-and-meta-analysis
#17
Eric J Vargas, Fateh Bazerbachi, Monika Rizk, Tarun Rustagi, Andres Acosta, Erik B Wilson, Todd Wilson, Manoel Galvao Neto, Natan Zundel, Manpreet S Mundi, Maria L Collazo-Clavell, Shah Meera, H S Abu-Lebdeh, Paul A Lorentz, Karen B Grothe, Matthew M Clark, Todd A Kellogg, Travis J McKenzie, Michael L Kendrick, Mark D Topazian, Christopher J Gostout, Barham K Abu Dayyeh
BACKGROUND AND AIMS: Many patients who undergo bariatric surgery will experience weight regain and effective strategies are needed to help these patients. A dilated gastrojejunal anastomosis (GJA) has been associated with weight recidivism after Roux-en-Y gastric bypass surgery (RYGB). Endoscopic transoral outlet reduction (TORe) with a full thickness endoscopic suturing device (Overstitch, Apollo Endosurgery, Austin, TX) is a minimally invasive therapeutic option. The primary aim of this project was to examine the safety and long-term efficacy data from three bariatric surgery centers and to conduct a systematic review and meta-analysis of the existing literature...
January 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/28491925/no-camphor-toxicity-in-cambodian-infants
#18
Casey R Johnson, Samuel G Porter, Debra Coats, Kyly C Whitfield, Khin Mengkheang, Mark D Topazian, Philip R Fischer
Thiamine deficiency and beriberi are prevalent in Cambodia, although most infants with nonspecific clinical symptoms of beriberi, including tachypnea, lack echocardiographic evidence diagnostic of the disease. Camphor activates transient receptor potential vanilloid 3 (TRPV3), a nonselective ion channel expressed in the medial preoptic nucleus of the hypothalamus and thought to be important for thermo-sensitivity. Because camphorated ointments are used commonly among Cambodian infants, we hypothesized that topical camphor modulates thermoregulatory behaviors, causing beriberi-simulating tachypnea, separate from any influence of thiamine deficiency...
2017: Global Pediatric Health
https://www.readbyqxmd.com/read/28451929/endoscopic-sleeve-gastroplasty-for-obesity-a-multicenter-study-of-248-patients-with-24-months-follow-up
#19
MULTICENTER STUDY
Gontrand Lopez-Nava, Reem Z Sharaiha, Eric J Vargas, Fateh Bazerbachi, Galvao Neto Manoel, Inmaculada Bautista-Castaño, Andres Acosta, Mark D Topazian, Manpreet S Mundi, Nikhil Kumta, Michel Kahaleh, Andrea Marie Herr, Alpana Shukla, Louis Aronne, Christopher J Gostout, Barham K Abu Dayyeh
BACKGROUND: Endoscopic sleeve gastroplasty (ESG) is a technique for managing mild to moderately obese patients. We aimed to evaluate the long-term outcomes, reproducibility, and predictors of weight response in a large multicenter cohort. METHODS: Patients who underwent ESG between January 2013 and December 2015 in three centers were retrospectively analyzed. All procedures were performed using the Apollo OverStitch device (Apollo Endosurgery, Austin, TX). We performed per protocol (PP) and intention-to-treat (ITT) analyses, where patients lost to follow-up were considered failures...
October 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28448071/azathioprine-maintenance-therapy-to-prevent-relapses-in-autoimmune-pancreatitis
#20
Nicolò de Pretis, Antonio Amodio, Laura Bernardoni, Pietro Campagnola, Fabiana Capuano, Suresh T Chari, Stefano Crinò, Armando Gabbrielli, Arianna Massella, Mark Topazian, Luca Frulloni
OBJECTIVES: Steroids are used to induce remission in autoimmune pancreatitis (AIP). Low-dosage steroid therapy or immunosuppressant (IMs) has been proposed as maintenance therapy to prevent AIP relapse. Few and conflicting data have been published on the efficacy of azathioprine (AZA) in preventing AIP relapse. The aim of this study was to evaluate the indication and efficacy of AZA as maintenance therapy to prevent disease relapse in AIP. METHODS: Patients suffering from AIP diagnosed according to the ICDC in type 1, type 2, and not otherwise specified (NOS) were divided in those treated with AZA (AZA(+) group) as maintenance therapy and not treated with maintenance therapy (AZA(-) group)...
April 27, 2017: Clinical and Translational Gastroenterology
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