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Resident Sleep

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https://www.readbyqxmd.com/read/28806609/sleep-disturbances-in-young-and-middle-aged-adults-empirical-patterns-and-related-factors-from-an-epidemiological-survey
#1
Wulf Rössler, Vladeta AjdacicGross, Nick Glozier, Stephanie Rodgers, Helene Haker, Mario Müller
BACKGROUND: Previous research suggests that sleep disorders are highly associated with other mental health problems. However, sleep problems even below the diagnostic threshold of sleep disorders are very common in the general population, which highly affects wellbeing and functioning. In order to broaden the focus beyond those severe cases we explored empirical patterns across the whole spectrum of sleep problems as well as associated clinical and other factors. METHOD: A representative community sample of N=1274 residents from the canton of Zurich was interviewed for sleep problems and diagnostic criteria for mental disorders as well as was given a number of mental health-related psychometrical checklists...
July 21, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28797869/association-of-inflammatory-cytokines-with-the-symptom-cluster-of-pain-fatigue-depression-and-sleep-disturbance-in-chinese-patients-with-cancer
#2
Yan-Bo Ji, Chun-Lu Bo, Xiu-Juan Xue, En-Ming Weng, Guang-Chao Gao, Bei-Bei Dai, Kai-Wen Ding, Cui-Ping Xu
CONTEXT: Pain, fatigue, depression, and sleep disturbance are common in patients with cancer and usually co-occur as a symptom cluster. However, the mechanism underlying this symptom cluster is unclear. OBJECTIVES: This study aimed to identify subgroups of cluster symptoms, compare demographic and clinical characteristics between subgroups, and examine the associations between inflammatory cytokines and cluster symptoms. METHODS: Participants were 170 Chinese inpatients with cancer from two tertiary hospitals...
August 7, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28794665/resident-wellness-institutional-trends-over-10-years-since-2003
#3
Dongseok Choi, Andrea Cedfeldt, Christine Flores, Kimberly Irish, Patrick Brunett, Donald Girard
BACKGROUND: The surveys in this study were carried out at the Graduate Medical Education Division at Oregon Health & Science University (OHSU). OHSU implemented two significant wellness initiatives: a wellness program in 2004, and a policy allowing 4 half-days off each academic year to pursue personal or family health care needs in 2010. This study provides a secondary data analysis of five cross-sectional surveys of career satisfaction of resident and fellow trainees. METHODS: All trainees were surveyed five times over a 10-year period using anonymous, cross-sectional web-based survey instruments...
2017: Advances in Medical Education and Practice
https://www.readbyqxmd.com/read/28778040/health-impacts-related-to-urban-and-transport-planning-a-burden-of-disease-assessment
#4
Natalie Mueller, David Rojas-Rueda, Xavier Basagaña, Marta Cirach, Tom Cole-Hunter, Payam Dadvand, David Donaire-Gonzalez, Maria Foraster, Mireia Gascon, David Martinez, Cathryn Tonne, Margarita Triguero-Mas, Antònia Valentín, Mark Nieuwenhuijsen
INTRODUCTION: Until now, estimates of the Global Burden of Disease (GBD) have mainly been produced on national or regional levels. These general estimates, however, are less useful for city governments who have to take decisions on local scales. To address this gap, we focused on the city-level burden of disease (BD) due to exposures affected by urban and transport planning. We conducted a BD assessment using the Urban and Transport Planning Health Impact Assessment (UTOPHIA) tool to estimate annual preventable morbidity and disability-adjusted life-years (DALYs) under compliance with international exposure recommendations for physical activity (PA), exposure to air pollution, noise, heat, and access to green spaces in Barcelona, Spain...
October 2017: Environment International
https://www.readbyqxmd.com/read/28777828/depression-anxiety-and-smartphone-addiction-in-university-students-a-cross-sectional-study
#5
Jocelyne Matar Boumosleh, Doris Jaalouk
OBJECTIVES: The study aims to assess prevalence of smartphone addiction symptoms, and to ascertain whether depression or anxiety, independently, contributes to smartphone addiction level among a sample of Lebanese university students, while adjusting simultaneously for important sociodemographic, academic, lifestyle, personality trait, and smartphone-related variables. METHODS: A random sample of 688 undergraduate university students (mean age = 20.64 ±1.88 years; 53% men) completed a survey composed of a) questions about socio-demographics, academics, lifestyle behaviors, personality type, and smartphone use-related variables; b) 26-item Smartphone Addiction Inventory (SPAI) Scale; and c) brief screeners of depression and anxiety (PHQ-2 and GAD-2), which constitute the two core DSM-IV items for major depressive disorder and generalized anxiety disorder, respectively...
2017: PloS One
https://www.readbyqxmd.com/read/28777362/-the-role-of-subjective-methods-for-the-evaluation-of-sleep-quality
#6
A Yu Gortseva, L S Korostovtseva, M V Bochkarev, Yu V Sviryaev, A O Konradi
AIM: To assess the accuracy of questions evaluating the quality and duration of sleep. MATERIAL AND METHODS: Target population included residents of St. Petersburg, who participated in the epidemiological study ESSE-RF. Out of 1417 participants, 136 individuals agreed to undergo additional sleep evaluation, and 49 subjects underwent polysomnography study for objective sleep evaluation. All participants were interviewed for subjective sleep assessment (standard questionnaires and Pittsburgh sleep quality index questionnaire)...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28767095/the-combined-effects-of-aircraft-and-road-traffic-noise-and-aircraft-and-railway-noise-on-noise-annoyance-an-analysis-in-the-context-of-the-joint-research-initiative-norah
#7
Jördis Wothge, Christin Belke, Ulrich Möhler, Rainer Guski, Dirk Schreckenberg
The Noise Related Annoyance Cognition and Health (NORAH) research initiative is one of the most extensive studies on the physiological and psychological long-term effects of transportation noise in Europe. It includes research on the quality of life and annoyance as well as cardiovascular effects, sleep disturbance, breast cancer, blood pressure, depression and the cognitive development of children. Within the realm of the annoyance module of the study approximately 10,000 residents of the Rhine-Main district were surveyed on the combined effects of transportation noise...
August 2, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28760800/protocol-for-a-prospective-longitudinal-study-of-risk-factors-for-hypertension-incidence-in-a-mexico-city-population-the-tlalpan-2020-cohort
#8
Eloisa Colín-Ramírez, Susana Rivera-Mancía, Oscar Infante-Vázquez, Raúl Cartas-Rosado, Jesús Vargas-Barrón, Magdalena Madero, Maite Vallejo
INTRODUCTION: Systemic hypertension (HTN) is a common risk factor for cardiovascular disease. In Mexico, HTN prevalence has increased over time and is currently 31%. Nonetheless, information about the country's HTN incidence and its associated risk factors is scarce. Understanding this condition is a priority for identifying the scope of primary prevention. The main objective of this study is to evaluate the effect of traditional and non-traditional risk factors on the incidence of HTN in a cohort of healthy Mexico City residents under biannual follow-up for 10 years...
July 31, 2017: BMJ Open
https://www.readbyqxmd.com/read/28752004/survey-of-knowledge-and-attitudes-about-obstructive-sleep-apnoea-among-italian-anaesthetists
#9
Ruggero Massimo Corso, Massimiliano Sorbello, Matteo Buccioli, Elisa Carretta, Oriana Nanni, Emanuele Piraccini, Guido Merli, Flavia Petrini, Arturo Guarino, Giulio Frova
OBJECTIVE: As the care of Obstructive Sleep Apnoea (OSA) patients remains heterogeneous, we hypothesized that it may reflect insufficient OSA knowledge/awareness among clinicians. METHODS: OSA Knowledge/Attitude Questionnaire (OSAKA) was translated into Italian and distributed to anaesthetists attending SIAARTI National Congress and Airways courses and Hands-on Workshops from October 2012 to June 2013. RESULTS: In total, 370 anaesthetists returned the questionnaires (response rate, 62%); the median (interquartile range [IQR]) knowledge score was 12 (10-14), and the range was 1-17 with no difference by gender, age, professional title or years of practice...
June 2017: Turkish Journal of Anaesthesiology and Reanimation
https://www.readbyqxmd.com/read/28746075/fatigue-in-residency-education-understanding-the-influence-of-work-hours-regulations-in-europe
#10
Taryn S Taylor, Pim W Teunissen, Tim Dornan, Lorelei Lingard
PURPOSE: Although one proposed solution to the problem of fatigued medical trainees is the implementation of work hours regulations, concerns about the effectiveness of these regulations are growing. Canada remains one of the few Western jurisdictions without legislated regulation. Recent research suggests that fatigue is a complex social construct, rather than simply a lack of sleep; thus, the authors explored how regulations and fatigue are understood in countries with established work hours frameworks to better inform other jurisdictions looking to address trainee fatigue...
July 25, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28738460/-association-between-sleep-and-leukocyte-telomere-length-in-middle-aged-and-older-adults
#11
H F Liu, F Li, Y H Wang, J H Chen, D X Peng, J Chen, L H Tan, X Mi, B H Zhao
Objective: To understand the association between peripheral leukocytes telomere length (TL) and sleep in middle-aged and old adults. Methods: A total of 176 middle-aged and old adults were investigated by using the Pittsburgh Sleep Quality Index and questionnaire. TL was measured by fluorescence quantitative PCR. The correlation and regression analysis between sleep and telomere length was performed. Results: TL had a mean T/S ratio of 0.995±0.23. There was a negative correlation between TL and age (r=-0.241, P=0...
July 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28727848/the-nuclear-proteome-of-trypanosoma-brucei
#12
Carina Goos, Mario Dejung, Christian J Janzen, Falk Butter, Susanne Kramer
Trypanosoma brucei is a protozoan flagellate that is transmitted by tsetse flies into the mammalian bloodstream. The parasite has a huge impact on human health both directly by causing African sleeping sickness and indirectly, by infecting domestic cattle. The biology of trypanosomes involves some highly unusual, nuclear-localised processes. These include polycistronic transcription without classical promoters initiated from regions defined by histone variants, trans-splicing of all transcripts to the exon of a spliced leader RNA, transcription of some very abundant proteins by RNA polymerase I and antigenic variation, a switch in expression of the cell surface protein variants that allows the parasite to resist the immune system of its mammalian host...
2017: PloS One
https://www.readbyqxmd.com/read/28714795/analysis-of-physical-activity-among-free-living-nonagenarians-from-a-sardinian-longevous-population
#13
Giovanni Mario Pes, Maria Pina Dore, Alessandra Errigo, Michel Poulain
Physical activity was identified as a major determinant of longevity. Using wearable accelerometers, we evaluated energy expenditure (EE), including resting- (REE) and total-energy expenditure, (TEE), physical activity level (PAL), percentage of PAL ≥ 3 metabolic equivalent tasks (METs), number of steps, resting index (RI%) and sleeping patterns in 44 free-living nonagenarians (27 men) residing in a Sardinian village famous for its longevous population. The average REE and TEE recorded were: men 1278 ± 161 kcal/day and 957 ± 110, and women: 2286 ± 541kcal/day and 1811 ± 308 in the women, respectively...
July 17, 2017: Journal of Aging and Physical Activity
https://www.readbyqxmd.com/read/28711423/randomized-trial-of-intelligent-sensor-system-for-early-illness-alerts-in-senior-housing
#14
Marilyn Rantz, Lorraine J Phillips, Colleen Galambos, Kari Lane, Gregory L Alexander, Laurel Despins, Richelle J Koopman, Marjorie Skubic, Lanis Hicks, Steven Miller, Andy Craver, Bradford H Harris, Chelsea B Deroche
OBJECTIVES: Measure the clinical effectiveness and cost effectiveness of using sensor data from an environmentally embedded sensor system for early illness recognition. This sensor system has demonstrated in pilot studies to detect changes in function and in chronic diseases or acute illnesses on average 10 days to 2 weeks before usual assessment methods or self-reports of illness. DESIGN: Prospective intervention study in 13 assisted living (AL) communities of 171 residents randomly assigned to intervention (n=86) or comparison group (n=85) receiving usual care...
July 12, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28709509/poor-tap-water-quality-experiences-and-poor-sleep-quality-during-the-flint-michigan-municipal-water-crisis
#15
Daniel J Kruger, Gergana D Kodjebacheva, Suzanne Cupal
OBJECTIVES: After inadequate official response to community concerns over water quality following changes in Flint's municipal water supply, this study sought evidence for a relationship between water quality and community mental health. DESIGN: The Speak to Your Health Community Survey is a community-based participatory component of the health surveillance system in Genesee County, Michigan. This cross-sectional survey recruits participants from every residential Census Tract of the county and strives for demographic representativeness...
August 2017: Sleep Health
https://www.readbyqxmd.com/read/28706938/inhibitors-of-glycosomal-protein-import-provide-new-leads-against-trypanosomiasis
#16
COMMENT
Vishal C Kalel, Leonidas Emmanouilidis, Maciej Dawidowski, Wolfgang Schliebs, Michael Sattler, Grzegorz M Popowicz, Ralf Erdmann
Vector-borne trypanosomatid parasite infections in tropical and sub-tropical countries constitute a major threat to humans and livestock. Trypanosoma brucei parasites are transmitted by tsetse fly and lead to African sleeping sickness in humans and Nagana in cattle. In Latin American countries, Trypanosoma cruzi infections spread by triatomine kissing bugs lead to Chagas disease. Various species of Leishmania transmitted to humans by phlebotomine sandflies manifest in a spectrum of diseases termed Leishmaniasis...
July 3, 2017: Microbial Cell
https://www.readbyqxmd.com/read/28704052/discovery-and-kinetic-profiling-of-7-aryl-1-2-4-triazolo-4-3-a-pyridines-positive-allosteric-modulators-of-the-metabotropic-glutamate-receptor-2
#17
Maarten L J Doornbos, José María Cid, Jordi Haubrich, Alexandro Nunes, Jasper W van de Sande, Sophie C Vermond, Thea Mulder-Krieger, Andrés A Trabanco, Abdellah Ahnaou, Wilhelmus H Drinkenburg, Hilde Lavreysen, Laura H Heitman, Adriaan P IJzerman, Gary Tresadern
We report the synthesis and biological evaluation of a series of 7-aryl-1,2,4-triazolo[4,3-a]pyridines with mGlu2 positive allosteric modulator (PAM) activity and affinity. Besides traditional in vitro parameters of potency and affinity, kinetic parameters kon, koff and residence time (RT) were determined. The PAMs showed various kinetic profiles; kon values ranged over 2 orders of magnitude, whereas RT values were within a 10-fold range. Association rate constant kon was linearly correlated to affinity. Evaluation of a short, medium, and long RT compound in a label-free assay indicated a correlation between RT and functional effect...
August 1, 2017: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28698341/sleeping-pill-use-in-brazil-a-population-based-cross-sectional-study
#18
Katia Kodaira, Marcus Tolentino Silva
OBJECTIVES: This study aimed to assess the prevalence of sleeping pill use in Brazil. DESIGN: A population-based cross-sectional study with a three-stage cluster sampling design (census tracts, households and adult residents) was used. SETTING: The Brazilian 2013 National Health Survey was used. PARTICIPANTS: The study population consisted of household residents aged ≥18 years. A total of 60 202 individuals were interviewed, including 52...
July 10, 2017: BMJ Open
https://www.readbyqxmd.com/read/28687081/potential-mediators-between-fibromyalgia-and-c-reactive-protein-results-from-a-large-u-s-community-survey
#19
Termeh Feinberg, Usha Sambamoorthi, Christa Lilly, Kim Karen Innes
BACKGROUND: Fibromyalgia, a potentially debilitating chronic pain syndrome of unknown etiology, may be characterized by inflammation. In this study, we investigated the relation of FMS to serum C-reactive protein (CRP) in a large population of adults (18+) and investigated the influence of other factors on this relationship, including BMI, comorbidities, as well as mood and sleep disturbance. METHODS: Participants were 52,535 Ohio Valley residents (Fibromyalgia n = 1125)...
July 7, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28675095/development-and-pilot-testing-of-an-objective-structured-clinical-examination-for-obstructive-sleep-apnea
#20
Nasir I Bhatti, Muhammad Abbas Abid, C Matthew Stewart, Carol Fleishman, Niall Jefferson, Stacey L Ishman
Objective Our aim was (1) to develop an objective structured clinical examination (OSCE) for obstructive sleep apnea (OSA) and (2) to test the reliability and evaluate the feasibility of this OSCE while assessing residents' clinical skills in multiple core competencies via the standardized patient methodology. Study Design Development of assessment tool. Setting Johns Hopkins Medicine Simulation Center. Subjects and Methods Residents of the Department of Otolaryngology-Head and Neck Surgery at The Johns Hopkins University School of Medicine were invited to participate...
June 1, 2017: Otolaryngology—Head and Neck Surgery
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