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https://www.readbyqxmd.com/read/27904630/a-survey-of-the-therapeutic-effects-of-vitamin-e-suppositories-on-vaginal-atrophy-in-postmenopausal-women
#1
Aazam Parnan Emamverdikhan, Nahid Golmakani, Sayyed ASajadi Tabassi, Malihe Hassanzadeh, Nooriyeh Sharifi, Mohammad Taghi Shakeri
BACKGROUND: Menopause is associated with various complications such as depression, sleep disorders, and genitourinary atrophy. Vaginal atrophy occurs due to the loss of steroid hormones, and its major symptoms include vaginal dryness, itching, dyspareunia, and bleeding after intercourse. According to the literature, vitamin E plays a key role in estrogen stability. The aim of this study was to compare the effects of vitamin E suppositories and conjugated estrogen vaginal cream on vaginal atrophy...
September 2016: Iranian Journal of Nursing and Midwifery Research
https://www.readbyqxmd.com/read/27904148/the-interaction-between-erectile-dysfunction-complaints-and-depression-in-men-a-cross-sectional-study-about-sleep-hormones-and-quality-of-life
#2
J H Soterio-Pires, C Hirotsu, L J Kim, L Bittencourt, S Tufik, M L Andersen
Depression (DEP) is one of the main disabling diseases and is considered a contributor factor for erectile dysfunction (ED). Both of these conditions may be associated with hormonal changes and sleep disturbances. We aimed to evaluate the interaction between ED complaints and depression symptoms on sleep parameters, hormone levels and quality of life in men. This was a cross-sectional study of 468 men aged 20-80 years. The participants were classified according to the presence of ED and/or DEP in groups of healthy individuals, ED, DEP and DEP with ED (DEP-ED)...
December 1, 2016: International Journal of Impotence Research
https://www.readbyqxmd.com/read/27900560/serum-leptin-obestatin-and-ghrelin-levels-and-gastric-emptying-rates-of-liquid-and-solid-meals-in-non-obese-rats-with-roux-en-y-bypass-surgery-or-prosthesis-placement-implications-for-the-role-of-vagal-afferents
#3
Yunus Yavuz, Zarife Nigar Özdemir Kumral, Gülsün Memi, Özge Dağdeviren Çevik, Cumhur Yeğen, Berrak Ç Yeğen
BACKGROUND: The present study aimed to investigate the effects of Roux-en-Y gastric bypass (RYGB) and prosthesis placement on gastric emptying rate in conjunction with serum ghrelin-obestatin-leptin responses in non-obese rats with intact or denervated afferent innervation. METHODS: Under anesthesia, male Sprague-Dawley rats underwent either sham operation, RYGB, prosthesis, and/or Gregory cannula placement. Three weeks later, liquid or solid gastric emptying tests were performed and serum ghrelin, leptin and obestatin levels were measured...
November 29, 2016: Obesity Surgery
https://www.readbyqxmd.com/read/27899308/insight-gained-from-genome-wide-interaction-and-enrichment-analysis-on-weight-gain-during-citalopram-treatment
#4
Henrik Thyge Corfitsen, Antonio Drago
Weight gain is a possible side effect of the pharmacological antidepressant treatments. Defining antidepressant prescriptions based on personal genetic makeups would decrease the risk of weight gain and increase the quality of the current antidepressant pharmacological treatments. 643 depressed, citalopram treated individuals with available clinical and genome-wide genetic information were investigated to identify the molecular pathways associated with weight gain. 111 individuals experienced weight gain during citalopram treatment...
November 26, 2016: Neuroscience Letters
https://www.readbyqxmd.com/read/27894924/antidepressant-like-effects-exerted-by-the-intranasal-administration-of-a-glucagon-like-peptide-2-derivative-containing-cell-penetrating-peptides-and-a-penetration-accelerating-sequence-in-mice
#5
Sachie Sasaki-Hamada, Ryuji Nakamura, Yusuke Nakao, Toshiki Akimoto, Emi Sanai, Mio Nagai, Michiko Horiguchi, Chikamasa Yamashita, Jun-Ichiro Oka
The intracerebroventicular (i.c.v.) administration of glucagon-like peptide-2 (GLP-2) to rodents was shown to have antidepressant-like effects in imipramine-resistant depression-model mice. In order to utilize GLP-2 as a clinical treatment tool for depression, we herein focused on the intranasal delivery that is non-invasive approach, because the i.c.v. administration is invasive and impractical. In the present study, we prepared a GLP-2 derivative containing cell penetrating peptides (CPPs) and a penetration accelerating sequence (PAS) (PAS-CPPs-GLP-2) for the intranasal (i...
November 25, 2016: Peptides
https://www.readbyqxmd.com/read/27887610/integral-strategy-to-supportive-care-in-breast-cancer-survivors-through-occupational-therapy-and-a-m-health-system-design-of-a-randomized-clinical-trial
#6
Mario Lozano-Lozano, Lydia Martín-Martín, Noelia Galiano-Castillo, Francisco Álvarez-Salvago, Irene Cantarero-Villanueva, Carolina Fernández-Lao, Carmen Sánchez-Salado, Manuel Arroyo-Morales
BACKGROUND: Technological support using e-health mobile applications (m-health) is a promising strategy to improve the adherence to healthy lifestyles in breast cancer survivors (excess in energy intake or low physical activity are determinants of the risk of recurrence, second cancers and cancer mortality). Moreover, cancer rehabilitation programs supervised by health professionals are needed due to the inherent characteristics of these breast cancer patients. Our main objective is to compare the clinical efficacy of a m-health lifestyle intervention system alone versus an integral strategy to improve Quality of Life in breast cancer survivors...
November 25, 2016: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/27886020/cranial-electrotherapy-stimulation-affects-mood-state-but-not-levels-of-peripheral-neurotrophic-factors-or-hypothalamic-pituitary-adrenal-axis-regulation
#7
Hee-Tae Roh, Wi-Young So
Cranial electrotherapy stimulation (CES) is reported to aid in relieving symptoms of depression and anxiety, though the mechanism underlying this effect remains unclear. Therefore, the present study aimed to evaluate changes in the hypothalamic-pituitary-adrenal (HPA) axis response and levels of neurotrophic factors, as well as changes in mood state, in patients undergoing CES therapy. Fifty healthy postmenopausal women were randomly assigned to either a Sham CES group (n = 25) or an Active CES group (n = 25)...
November 18, 2016: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/27875437/newscap-research-identifies-link-between-hormonal-contraception-in-women-and-depression
#8
(no author information available yet)
No abstract text is available yet for this article.
December 2016: American Journal of Nursing
https://www.readbyqxmd.com/read/27872581/a-trigger-for-opioid-misuse-chronic-pain-and-stress-dysregulate-the-mesolimbic-pathway-and-kappa-opioid-system
#9
REVIEW
Nicolas Massaly, Jose A Morón, Ream Al-Hasani
Pain and stress are protective mechanisms essential in avoiding harmful or threatening stimuli and ensuring survival. Despite these beneficial roles, chronic exposure to either pain or stress can lead to maladaptive hormonal and neuronal modulations that can result in chronic pain and a wide spectrum of stress-related disorders including anxiety and depression. By inducing allostatic changes in the mesolimbic dopaminergic pathway, both chronic pain and stress disorders affect the rewarding values of both natural reinforcers, such as food or social interaction, and drugs of abuse...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/27870419/sex-differences-in-brain-derived-neurotrophic-factor-signaling-and-functions
#10
REVIEW
Chi Bun Chan, Keqiang Ye
Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family that plays a critical role in numerous neuronal activities. Recent studies have indicated that some functions or action mechanisms of BDNF vary in a sex-dependent manner. In particular, BDNF content in some brain parts and the tendency to develop BDNF deficiency-related diseases such as depression are greater in female animals. With the support of relevant studies, it has been suggested that sex hormones or steroids can modulate the activities of BDNF, which may account for its functional discrepancy in different sexes...
January 2, 2017: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/27870416/sex-specific-mechanisms-for-responding-to-stress
#11
REVIEW
Debra A Bangasser, Brittany Wicks
Posttraumatic stress disorder and major depression share stress as an etiological contributor and are more common in women than in men. Traditionally, preclinical studies investigating the neurobiological underpinnings of stress vulnerability have used only male rodents; however, recent studies that include females are finding sex-specific mechanisms for responding to stress. This Mini-Review examines recent literature using a framework developed by McCarthy and colleagues (2012; J Neurosci 32:2241-2247) that highlights different types of sex differences...
January 2, 2017: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/27868174/-acromegaly-recognition-of-a-rare-disease-in-psychiatric-practice
#12
A J de Kort, D Postulart, G A A M Wetzer, S H P P Roerink
Acromegaly is a rare disease which is caused by a tumour in the anterior lobe of the pituitary gland. The tumour stimulates excessive production of the growth hormone. As a result, all the organs and tissues in the body are induced to grow. This growth is responsible for a wide range of symptoms, some of which can be neuro-psychiatric.<br/> AIM: To promote the early detection of acromegaly so that treatment can be started as soon as possible and further damage can be prevented.<br/> METHOD: We searched PubMed for articles relating to quality of life and cognitive, psychological and psychiatric symptoms and personality changes associated with acromegaly...
2016: Tijdschrift Voor Psychiatrie
https://www.readbyqxmd.com/read/27861545/glucocorticoid-induces-incoordination-between-glutamatergic-and-gabaergic-neurons-in-the-amygdala
#13
Guang-Yan Wang, Zhao-Ming Zhu, Shan Cui, Jin-Hui Wang
BACKGROUND: Stressful life leads to mood disorders. Chronic mild stress is presumably major etiology for depression, and acute severe stress leads to anxiety. These stressful situations may impair hypothalamus-pituitary-adrenal axis and in turn induce synapse dysfunction. However, it remains elusive how the stress hormones mess up subcellular compartments and interactions between excitatory and inhibitory neurons, which we have investigated in mouse amygdala, a structure related to emotional states...
2016: PloS One
https://www.readbyqxmd.com/read/27854559/the-influence-of-cyclic-hormonal-contraception-on-expression-of-premenstrual-syndrome
#14
Kimberly A Yonkers, Brianna Cameron, Ralitza Gueorguieva, Margaret Altemus, Susan G Kornstein
BACKGROUND: Some women who use cyclic hormonal contraception (CHC) suffer from premenstrual symptoms; whether their symptoms differ from women who do not use CHC is not clear. OBJECTIVE: To compare women who use or do not use CHC on perimenstrual symptom timing and change severity. STUDY DESIGN: We analyzed daily symptom ratings from women who requested participation in (Screened Cohort: 103 used CHC and 387 did not) or were randomized in (Randomized Cohort: 41 used CHC and 211 did not) a clinical trial for premenstrual syndrome...
November 17, 2016: Journal of Women's Health
https://www.readbyqxmd.com/read/27847201/different-effects-of-vitamin-d-hormone-treatment-on-depression-like-behavior-in-the-adult-ovariectomized-female-rats
#15
Julia Fedotova, Tatyana Dudnichenko, Peter Kruzliak, Zhanna Puchavskaya
Vitamine D (VD) has important functions in the human brain and may play a role in affective-related disorders. VD receptors are expressed in multiple brain regions associated with depressive disorders. The aim of the preclinical study was to examine the effects of chronic cholecalciferol administration (1.0, 2.5 or 5.0mg/kg/day,s.c., once daily, for 14days) on the depression-like behavior and corticosterone levels in the blood samples following ovariectomy in female rats. Cholecalciferol was administered to the ovariectomized (OVX) rats and OVX rats treated with 17β-estradiol (17β-E2, 0...
November 12, 2016: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/27847123/leaf-biochemical-responses-and-fruit-oil-quality-parameters-in-olive-plants-subjected-to-airborne-metal-pollution
#16
Radhia Fourati, Antonio Scopa, Chedlia Ben Ahmed, Ferjani Ben Abdallah, Roberto Terzano, Concetta Eliana Gattullo, Ignazio Allegretta, Fernanda Galgano, Marisa Carmela Caruso, Adriano Sofo
This study was carried out in two olive orchards (Olea europaea L., cv. Chemlali) located in a polluted area near a fertilizers factory and in a control unpolluted site, managed with similar cultivation techniques. The aim was to investigate the physiological and biochemical responses of polluted plants (PP), exposed to atmospheric metal contamination (Cd, Cu, Fe, Mn, Ni and Pb) as compared to control plants (CP). Leaves, roots and fruits of PP showed a depression of their non-enzymatic and enzymatic antioxidant defences and a disruption of their hormonal homeostasis...
November 12, 2016: Chemosphere
https://www.readbyqxmd.com/read/27845188/anxiety-and-depressive-like-profiles-during-early-and-mid-adolescence-in-the-female-wistar-kyoto-rat
#17
Deepthi D'Souza, Monika Sadananda
Approaches for the development of preclinical models of depression extensively use adult and male animals owing to the discrepancies arising out of the hormonal flux in adult females and adolescents during attainment of puberty. Thus the increased vulnerability of females towards clinical depression and anxiety-related disorders remains incompletely understood. Development of clinical models of depression in adolescent females is essential in order to evolve effective treatment strategies for adolescent depression...
November 11, 2016: International Journal of Developmental Neuroscience
https://www.readbyqxmd.com/read/27843859/a-study-to-find-depression-in-patients-attending-dermatological-opd-in-a-teaching-hospital
#18
Abhinit Kumar, Kunal Kumar, Praneta Swarup, Shitiz Goel, Abhay Singh Tomar
INTRODUCTION: The relationship between skin and the brain exists because the brain, as the center of psychological functions, and the skin have the same ectodermal origin and are affected by the same hormones and neurotransmitters. Skin disorder can be a potential source of emotional distress and psychiatric illness leading to impaired psychosocial adjustments. AIMS AND OBJECTIVES: The aim and objective of this study was to find psychiatric depression in patients attending dermatology outpatient department (OPD)...
April 2016: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/27837330/reinforcing-properties-of-an-intermittent-low-dose-of-ketamine-in-rats-effects-of-sex-and-cycle
#19
Katherine N Wright, Caroline E Strong, Marjorie N Addonizio, Naomi C Brownstein, Mohamed Kabbaj
RATIONALE: Repeated intermittent exposure to ketamine has rapid and long-lasting antidepressant effects, but the abuse potential has only been assessed at high doses. Furthermore, while females are more susceptible to depression and more sensitive to ketamine's antidepressant-like effects, the abuse potential for ketamine in females is unknown. OBJECTIVES: The objectives of this study are to determine the reinforcing properties of low-dose intermittent ketamine in adult rats of both sexes and determine whether cycling gonadal hormones influence females' response to ketamine...
November 11, 2016: Psychopharmacology
https://www.readbyqxmd.com/read/27836433/sex-differences-in-the-epidemiology-clinical-features-and-pathophysiology-of-migraine
#20
REVIEW
Kjersti Grøtta Vetvik, E Anne MacGregor
Migraine is two to three times more prevalent in women than men, and women report a longer attack duration, increased risk of headache recurrence, greater disability, and a longer period of time required to recover. Conditions recognised to be comorbid with migraine include asthma, anxiety, depression, and other chronic pain conditions, and these comorbidities add to the amount of disability in both sexes. Migraine-specifically migraine with aura-has been identified as a risk factor for vascular disorders, particularly in women, but because of the scarcity of data, the comparative risk in men has yet to be established...
November 8, 2016: Lancet Neurology
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