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https://www.readbyqxmd.com/read/28811802/clinical-features-and-risk-factors-for-irritable-bowel-syndrome-in-migraine-patients
#1
Chunlin Li, Shengyuan Yu, Huiying Li, Jin Zhou, Jieqiong Liu, Wenjing Tang, Lei Zhang
OBJECTIVE: Clinical and basic research increasingly suggests a correlation between migraine and irritable bowel syndrome (IBS). In this study, we aimed to explore the clinical features and risk factors for IBS in migraine patients. METHODS: This was a retrospective, cross-sectional study. A total of 1,112 consecutive patients from the internal medicine and emergency departments of three hospitals from June 2014 through 2016. A comprehensive interviewer-administered questionnaire was designed based on the International Classification of Headache Disorders, 3rd edition (beta version)...
May 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28811352/patient-acceptable-symptom-state-in-knee-osteoarthritis-patients-succeeds-across-different-patient-reported-outcome-measures-assessing-physical-function-but-fails-across-other-dimensions-and-rheumatic-diseases
#2
Elien A M Mahler, Nadine Boers, Johannes W J Bijlsma, Frank H J van den Hoogen, Alfons A den Broeder, Cornelia H M van den Ende
OBJECTIVE: The aims of this study are (1) to establish the Patient Acceptable Symptom State (PASS) cutoff values of different patient-reported outcome measures (PROM) assessing physical function in patients with knee osteoarthritis (OA), and (2) to assess the influence of sex, age, duration of symptoms, and presence of depressive feelings on being in PASS. METHODS: Patients fulfilling the clinical American College of Rheumatology knee OA criteria received standardized nonsurgical treatment and completed different questionnaires at baseline and 3 months assessing physical function: Knee Injury and Osteoarthritis Outcome Score, Lequesne Algofunctional Index, Lower Extremity Functional Scale, numerical rating scale, and the physical function subscale of the Western Ontario and McMaster Universities Osteoarthritis Index...
August 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28807027/health-related-quality-of-life-in-the-brazilian-amazon-a-population-based-cross-sectional-study
#3
Marcus Tolentino Silva, Monica Caicedo Roa, Tais Freire Galvao
BACKGROUND: To analyze perceptions of health-related quality of life and associated factors in populations from the Manaus Metropolitan Region. METHODS: We conducted a population-based cross-sectional study from May to August 2015. Adults aged 18 years and older were selected using probabilistic three-phase cluster sampling and stratified by sex and age, based on official estimates. Quality of life data were collected using the European Quality of Life 5-Dimensions 3-Levels (EQ-5D-3L) along with socioeconomic, demographic, and health perception data...
August 14, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28797869/association-of-inflammatory-cytokines-with-the-symptom-cluster-of-pain-fatigue-depression-and-sleep-disturbance-in-chinese-patients-with-cancer
#4
Yan-Bo Ji, Chun-Lu Bo, Xiu-Juan Xue, En-Ming Weng, Guang-Chao Gao, Bei-Bei Dai, Kai-Wen Ding, Cui-Ping Xu
CONTEXT: Pain, fatigue, depression, and sleep disturbance are common in patients with cancer and usually co-occur as a symptom cluster. However, the mechanism underlying this symptom cluster is unclear. OBJECTIVES: This study aimed to identify subgroups of cluster symptoms, compare demographic and clinical characteristics between subgroups, and examine the associations between inflammatory cytokines and cluster symptoms. METHODS: Participants were 170 Chinese inpatients with cancer from two tertiary hospitals...
August 7, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28796560/facial-emotion-decoding-in-patients-with-parkinson-s-disease
#5
Marco De Risi, Giancarlo Di Gennaro, Angelo Picardi, Sara Casciato, Liliana G Grammaldo, Alfredo D'Aniello, Deborah Lanni, Stefano Meletti, Nicola Modugno
PURPOSE: In line with the growing attention on non-motor symptoms and disturbance of affective and emotional processing in Parkinson's disease, we aimed to study different aspects of facial emotion expression evaluation in a group of PD without cognitive decline in treatment with common antiparkinsonian drugs, matched for sex, age, and education with healthy subjects. MATERIALS AND METHODS: The study was conducted on 30 patients (13 male; mean age: 63.3±6.7; mean age of disease onset: 56...
August 10, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28796415/white-matter-tract-integrity-is-associated-with-antidepressant-response-to-lurasidone-in-bipolar-depression
#6
Martin J Lan, Harry Rubin-Falcone, Fatima Motiwala, Ying Chen, Jonathan W Stewart, David J Hellerstein, J John Mann, Patrick J McGrath
OBJECTIVES: Patients with bipolar disorder spend the most time in the depressed phase, and that phase is associated with the most morbidity and mortality. Treatment of bipolar depression lacks a test to determine who will respond to treatment. White matter disruptions have been found in bipolar disorder. Previous reports suggest that white matter disruptions may be associated with resistance to antidepressant medication, but this has never been investigated in a prospective study using a Food and Drug Administration (FDA)-approved medication...
August 10, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/28795307/sex-symptom-severity-and-quality-of-life-in-rheumatology
#7
REVIEW
Marco Krasselt, Christoph Baerwald
Inflammatory rheumatic diseases such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) show a striking female predominance ranging from 3:1 in RA up to 9:1 in SLE. The background for those gender bias is not fully understood yet, but seems to be the result of a complex interaction between sex hormones, (epi-)genetics, and possibly even the composition of gut microbiota. Moreover, time of disease onset, the clinical phenotype including co-morbidities as well as the course of the diseases during life differ between genders...
August 9, 2017: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/28792529/discrepancy-between-self-assessed-hearing-status-and-measured-audiometric-evaluation
#8
So Young Kim, Hyung-Jong Kim, Min-Su Kim, Bumjung Park, Jin-Hwan Kim, Hyo Geun Choi
OBJECTIVE: The purpose of this study was to examine the difference between self-reported hearing status and hearing impairment assessed using conventional audiometry. The associated factors were examined when a concordance between self-reported hearing and audiometric measures was lacking. METHODS: In total, 19,642 individuals ≥20 years of age who participated in the Korea National Health and Nutrition Examination Surveys conducted from 2009 through 2012 were enrolled...
2017: PloS One
https://www.readbyqxmd.com/read/28789949/reduced-hippocampal-il-10-expression-altered-monoaminergic-activity-and-anxiety-and-depressive-like-behavior-in-female-mice-subjected-to-chronic-social-instability-stress
#9
Ainitze Labaka, Eneritz Gómez-Lázaro, Oscar Vegas, Joana Pérez-Tejada, Amaia Arregi, Larraitz Garmendia
Evidence indicates that release of pro-inflammatory cytokines induced by social stress contributes to affective disorders. Additionally, there are known sex differences in both the stress response and the stressors that can elicit this response. In this regard, the chronic social instability (CSI) rodent model of stress appears to be the best fit for the social nature of females. This study analyzed the effects of CSI on female mouse behavior, hippocampal cytokine expression, tryptophan metabolism and monoaminergic activity...
August 5, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28781737/multidrug-intolerance-in-the-treatment-of-hypertension-result-from-an-audit-of-a-specialized-hypertension-service
#10
Basil N Okeahialam
BACKGROUND: Hypertension as a cardiovascular disease risk factor continues to take a heavy toll on the population despite efforts with containment. Poor control, even among those on treatment, is part of the challenge and results from patient, physician and health system factors. When the problem resides at patient level, adherence is largely responsible. An entity defined as multidrug intolerance (MDI) is hardly considered. A situation when a patient is willing to adhere but is compelled otherwise could frustrate both patient and physician...
August 2017: Therapeutic Advances in Drug Safety
https://www.readbyqxmd.com/read/28780279/personality-disorders-and-somatization-in-functional-and-organic-movement-disorders
#11
Giovanni Defazio, Adriana Pastore, Roberta Pellicciari, Grazia Pierri, Angelo F Gigante, Giada Fabio, Maria Superbo, Francesco Margari
Psychiatric disturbances and somatizations are both criteria which support the diagnosis of functional movement disorders. It is unclear, however, whether these factors are helpful in differentiating functional and organic movement disorders. To address this issue, the Structured Clinical Interview for DSM-IV Axis I and II psychiatric disorders, the State-Trait Anxiety Inventory, the Beck Depression Inventory and the "somatization section" of the Dissociative Disorders Interview Schedule were administered to 31 functional movement disorder patients diagnosed, according to Fahn and Williams criteria and 31 sex- and age-matched control outpatients, with adult-onset dystonia...
July 31, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28776419/psychiatric-assessments-in-patients-operated-on-due-to-lung-cancer
#12
Yeliz Erol, Alpaslan Çakan, Ayşe Gül Ergönül, Özen Sertöz, Ali Özdil, Kutsal Turhan, Ufuk Çağirici
Background This study was undertaken to determine the relationship between preoperative and postoperative psychiatric status and postoperative complications in patients operated on due to lung cancer. Methods We prospectively enrolled 25 patients undergoing surgery with a diagnosis of lung cancer. There were 17 (68%) males, 8 (32%) females, and the mean age was 61 ± 8.9 years (range 38-81 years). Their psychiatric status was assessed using the Experiences in Close Relationships Scale II, European Organization for Research and Treatment of Cancer Quality-of-Life Questionnaire C30, Perceived Family Support Scale, the combined Stress Thermometer and Hospital Anxiety Depression Scale, in the preoperative period, and the Perceived Family Support, Stress Thermometer, and European Organization for Research and Treatment of Cancer Quality-of-Life Questionnaire C30 at 1 month postoperatively...
January 1, 2017: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/28771498/autonomy-connectedness-mediates-sex-differences-in-symptoms-of-psychopathology
#13
Marrie H J Bekker, Marcel A L M van Assen
OBJECTIVES: This study aimed to examine if autonomy-connectedness, capacity for self-governance under the condition of connectedness, would mediate sex differences in symptoms of various mental disorders (depression, anxiety, eating disorders, antisocial personality disorder). METHOD: Participants (N = 5,525) from a representative community sample in the Netherlands filled out questionnaires regarding the variables under study. RESULTS: Autonomy-connectedness (self-awareness, SA; sensitivity to others, SO; capacity for managing new situations, CMNS) fully mediated the sex differences in depression and anxiety, and partly in eating disorder -(drive for thinness, bulimia, and body dissatisfaction) and anti-social personality disorder characteristics...
2017: PloS One
https://www.readbyqxmd.com/read/28767456/effects-of-anaesthesia-and-analgesia-on-long-term-outcome-after-total-knee-replacement-a-prospective-observational-multicentre-study
#14
Dario Bugada, Massimo Allegri, Marco Gemma, Andrea L Ambrosoli, Giuseppe Gazzerro, Fernando Chiumiento, Doriana Dongu, Fiorella Nobili, Andrea Fanelli, Paolo Ferrua, Massimo Berruto, Gianluca Cappelleri
BACKGROUND: Perioperative regional anaesthesia may protect from persistent postsurgical pain (PPSP) and improve outcome after total knee arthroplasty (TKA). OBJECTIVES: Aim of this study was to evaluate the impact of regional anaesthesia on PPSP and long-term functional outcome after TKA. DESIGN: A web-based prospective observational registry. SETTING: Five Italian Private and University Hospitals from 2012 to 2015. PATIENTS: Undergoing primary unilateral TKA, aged more than 18 years, informed consent, American Society of Anesthesiologists (ASA) physical status classes 1 to 3, no previous knee surgery...
August 1, 2017: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/28767135/phenotypic-outcomes-in-adolescence-and-adulthood-in-the-scarcity-adversity-model-of-low-nesting-resources-outside-the-home-cage
#15
Tiffany S Doherty, Jennifer Blaze, Samantha M Keller, Tania L Roth
Early life adversity is known to disrupt behavioral trajectories and many rodent models have been developed to characterize these stress-induced outcomes. One example is the scarcity-adversity model of low nesting resources. This model employs resource scarcity (i.e., low nesting materials) to elicit adverse caregiving conditions (including maltreatment) toward rodent neonates. Our lab utilizes a version of this model wherein caregiving exposures occur outside the home cage during the first postnatal week. The aim of this study was to determine adolescent and adult phenotypic outcomes associated with this model, including assessment of depressive- and anxiety-like behaviors and performance in different cognitive domains...
August 2, 2017: Developmental Psychobiology
https://www.readbyqxmd.com/read/28762055/gulf-war-illness-gwi-as-a-neuroimmune-disease
#16
Apostolos P Georgopoulos, Lisa M James, Adam F Carpenter, Brian E Engdahl, Arthur C Leuthold, Scott M Lewis
Gulf War illness (GWI) is a chronic disease characterized by the involvement of several organs, including the brain (Christova et al., Exp Brain Res doi: 10.1007/s00221-017-5010-8 , 2017). In a previous study (Georgopoulos et al., J Neural Eng 4:349-355, 2015), we identified six protective alleles from Class II human leukocyte antigen (HLA) genes, and more recently, we investigated the brain correlates of this protection (James et al., EBioMedicine 13:72-79, 2016). Those and other studies (Israeli, Lupus, 21:190-194, 2012) suggested an involvement of the immune system in GWI...
July 31, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28760765/high-sex-ratios-in-rural-china-declining-well-being-with-age-in-never-married-men
#17
Xudong Zhou, Therese Hesketh
In parts of rural China male-biased sex ratios at birth, combined with out-migration of women, have led to highly male-biased adult sex ratios, resulting in large numbers of men being unable to marry, in a culture where marriage and reproduction are an expectation. The aim of this study was to test the hypotheses that older unmarried men are more predisposed to depression, low self-esteem and aggression than both those who are married, and those who are younger and unmarried. Self-completion questionnaires were administered among men aged 20-40 in 48 villages in rural Guizhou province, southwestern China...
September 19, 2017: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/28759400/body-composition-in-adolescents-during-treatment-with-selective-serotonin-reuptake-inhibitors
#18
Chadi A Calarge, James A Mills, Kathleen F Janz, Trudy L Burns, William H Coryell, Babette S Zemel
OBJECTIVES: To examine the independent contribution of major depressive disorder (MDD), generalized anxiety disorder (GAD), and selective serotonin reuptake inhibitors (SSRIs) to changes in body composition in older adolescents. METHODS: Medically healthy 15- to 20-year-olds who were unmedicated or within 1 month of starting an SSRI were prospectively followed. Psychiatric functioning and medication treatment were assessed monthly. Body Mass Index (BMI) was measured every 4 months...
July 2017: Pediatrics
https://www.readbyqxmd.com/read/28759308/vasopressin-deletion-is-associated-with-sex-specific-shifts-in-the-gut-microbiome
#19
Christopher T Fields, Benoit Chassaing, Matthew J Paul, Andrew T Gewirtz, Geert J de Vries
Brattleboro rats harbor a spontaneous deletion of the arginine-vasopressin (Avp) gene. In addition to diabetes insipidus, these rats exhibit low levels of anxiety and depressive behaviors. Recent work on the gut-brain axis has revealed that gut microbiota can influence anxiety behaviors. Therefore, we studied the effects of Avp gene deletion on gut microbiota. Since Avp gene expression is sexually different, we also examined how Avp deletion affects sex differences in gut microbiota. Males and females show modest but differentiated shifts in taxa abundance across 3 separate Avp deletion genotypes: wildtype (WT), heterozygous (Het) and AVP-deficient Brattleboro (KO) rats...
July 31, 2017: Gut Microbes
https://www.readbyqxmd.com/read/28758586/effects-of-the-disease-characteristics-and-the-treatment-on-psychological-status-in-patients-with-rheumatoid-arthritis-and-ankylosing-spondylitis
#20
Selin Aktürk Esen, İrfan Esen, Yusuf Karabulut, Volkan Atmiş
INTRODUCTION: Various psychiatric disorders, especially depression and anxiety, are seen in 2/3 of the chronic rheumatic diseases with chronic pain. In this study, we aimed to define the effect of the disease variables and the treatment on depression and anxiety in rheumatoid arthritis (RA) and ankylosing spondylitis (AS) patients. METHOD: 46 patients with RA, 43 patients with AS and 29 healthy volunteers were evaluated with Beck Depression Inventory (BAI) and Beck Anxiety Inventory (BAI)...
July 28, 2017: Current Rheumatology Reviews
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