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Sex differences, depression

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https://www.readbyqxmd.com/read/28080186/satisfaction-with-sex-life-in-sexually-active-heterosexual-couples-dealing-with-breast-cancer-a-nationwide-longitudinal-study
#1
Nina Rottmann, Dorte Gilså Hansen, René dePont Christensen, Mariët Hagedoorn, Morten Frisch, Anne Nicolaisen, Niels Kroman, Henrik Flyger, Christoffer Johansen
BACKGROUND: A breast cancer (BC) diagnosis can profoundly affect the sex life of patient and partner within a couple. The purpose of the present study is to examine whether individual and partner sexual functioning, affectionate behavior, emotional closeness and depressive symptoms are associated with change over time in satisfaction with sex life of sexually active heterosexual couples dealing with BC and to explore whether the associations differ between patients and partners after adjustment for basic sociodemographic characteristics, comorbidity and BC treatment...
January 12, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28077689/giant-cell-arteritis-and-vascular-disease-risk-factors-and-outcomes-a-cohort-study-using-uk-clinical-practice-research-datalink
#2
Lin Li, Tuhina Neogi, Susan Jick
OBJECTIVE: To evaluate the associations between GCA and vascular diseases and other comorbidities in patients with GCA compared with non-vasculitis patients. METHODS: Using the UK-based Clinical Practice Research Datalink we identified 9778 newly diagnosed GCA patients in 1990-2014, and up to 10 non-vasculitis patients randomly matched to each case on age, sex, practice and years of history before cohort entry. We compared the distributions of 9 different pre-existing vascular diseases and 11 other comorbidities, and risks of incident vascular diseases and other comorbidities after cohort entry between GCA and non-vasculitis patients...
January 11, 2017: Rheumatology
https://www.readbyqxmd.com/read/28077120/altered-fractional-amplitude-of-low-frequency-fluctuation-associated-with-cognitive-dysfunction-in-first-episode-drug-na%C3%A3-ve-major-depressive-disorder-patients
#3
Manli Huang, Shaojia Lu, Liang Yu, Lingjiang Li, Peng Zhang, Jianbo Hu, Weihua Zhou, Shaohua Hu, Ning Wei, Jinwen Huang, Jian Weng, Yi Xu
BACKGROUND: Previous studies have demonstrated that abnormities of both resting-state brain activity and cognitive dysfunction are frequently observed in patients with major depressive disorder (MDD). However, the underlying relationship between these two aspects is less investigated. In this context, the aim of the present study was to investigate the association between cognitive dysfunction and altered resting-state brain function in first-episode drug-naïve MDD patients. METHODS: Twenty-five drug-naïve MDD patients and twenty-six age-, sex-, and education-matched normal controls were recruited in this study...
January 11, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28072643/early-life-trauma-in-hospitalized-patients-with-mood-disorders-and-its-association-with-clinical-outcomes
#4
Ajay K Parsaik, Noha Abdelgawad, Jigar K Chotalia, Scott D Lane, Teresa A Pigott
BACKGROUND: The prevalence of childhood trauma and its impact on clinical outcomes in hospitalized patients with mood disorders is unknown. We studied the frequency of childhood trauma among inpatient adults with mood disorders and its association with clinical outcomes. METHODS: Patients admitted to our hospital with a primary diagnosis of mood disorders completed the short form of the Early Trauma Inventory-Self-Report (ETISR-SF), the Sheehan Disability Scale, and the Clinician-Rated Dimensions of Psychosis Symptom Severity scale...
January 2017: Journal of Psychiatric Practice
https://www.readbyqxmd.com/read/28069620/prenatal-exposure-to-antiepileptic-drugs-and-use-of-primary-healthcare-during-childhood-a-population-based-cohort-study-in-denmark
#5
Anne Mette Würtz, Dorte Rytter, Claus Høstrup Vestergaard, Jakob Christensen, Mogens Vestergaard, Bodil Hammer Bech
OBJECTIVE: Prenatal exposure to antiepileptic drugs (AEDs) has been associated with adverse outcomes in the offspring such as congenital malformations and neuropsychiatric disorders. The objective of this study was to investigate whether prenatal exposure to AEDs is also associated with more frequent use of primary healthcare during childhood. DESIGN: Population-based cohort study. SETTING: Nationwide national registers in Denmark. PARTICIPANTS: All live-born singletons in Denmark during 1997-2012 identified in the Danish National Patient Register and followed until 31 December 2013 (n=963 010)...
January 5, 2017: BMJ Open
https://www.readbyqxmd.com/read/28066005/metabolic-syndrome-and-central-obesity-in-depression-a-cross-sectional-study
#6
Anju Agarwal, Manu Agarwal, Kabir Garg, Pronob Kumar Dalal, Jitendra Kumar Trivedi, J S Srivastava
INTRODUCTION: The current epidemiological data and meta-analyses indicate a bidirectional association between depression and metabolic syndrome (MetS). AIMS: To assess the prevalence of metabolic syndrome and obesity in drug naïve patients (in current episode) having Recurrent Major Depressive Disorder and Bipolar Depression. METHOD: This was a single point cross sectional observational study that involved administration of diagnostic and assessment tools and blood investigations...
July 2016: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/28063879/the-effect-of-vishram-a-grass-roots-community-based-mental-health-programme-on-the-treatment-gap-for-depression-in-rural-communities-in-india-a-population-based-study
#7
Rahul Shidhaye, Vaibhav Murhar, Siddharth Gangale, Luke Aldridge, Rahul Shastri, Rachana Parikh, Ritu Shrivastava, Suvarna Damle, Tasneem Raja, Abhijit Nadkarni, Vikram Patel
BACKGROUND: VISHRAM was a community-based mental health programme with the goal of addressing the mental health risk factors for suicide in people from 30 villages in the Amravati district in Vidarbha, central India. We aimed to assess whether implementation of VISHRAM was associated with an increase in the proportion of people with depression who sought treatment (contact coverage). METHODS: A core strategy of VISHRAM was to increase the demand for care by enhancing mental health literacy and to improve the supply of evidence-based interventions for depression and alcohol-use disorders...
January 4, 2017: Lancet Psychiatry
https://www.readbyqxmd.com/read/28057525/lipopolysaccharide-administration-induces-sex-dependent-behavioural-and-serotonergic-neurochemical-signatures-in-mice
#8
Jonathon Sens, Eric Schneider, Joseph Mauch, Anna Schaffstein, Sara Mohamed, Kathryn Fasoli, Joseph Saurine, Aikaterini Britzolaki, Connor Thelen, Pothitos M Pitychoutis
Challenging the innate immune machinery with the pro-inflammatory agent lipopolysaccharide (LPS) results in the development of a sickness syndrome characterized by numerous depressive-like behavioural and physiological manifestations, most of which overlap with the clinical symptoms of major depression. Although women are known to mount stronger pro-inflammatory responses during infections and being at higher risk to develop depressive disorders compared to men, the vast majority of experimental studies investigating the neurobiological effects of LPS administration have been conducted in males...
January 3, 2017: Pharmacology, Biochemistry, and Behavior
https://www.readbyqxmd.com/read/28056616/adolescents-transitioning-to-high-school
#9
Susan G Williams, Jennifer Langhinrichsen-Rohling, Cory Wornell, Heather Finnegan
Adolescents transitioning to high school may be at greater risk of depression and suicide if they are victims of bullying behavior. This study explored sex differences in bullying victimization (physical, verbal/social, and cyberbullying) and the impact on depressive symptoms and suicidal behaviors in ninth-grade students ( N = 233). Females reported significantly more verbal/social and cyberbullying than male students. There were no significant sex differences in physical bullying; male students who reported physical bullying victimization were more likely to experience depressive symptoms...
January 1, 2017: Journal of School Nursing: the Official Publication of the National Association of School Nurses
https://www.readbyqxmd.com/read/28049102/prevalence-and-clinical-severity-of-mood-disorders-among-first-second-and-third-generation-migrants
#10
Baptiste Pignon, Geoffroy Pierre Alexis, Pierre Thomas, Jean-Luc Roelandt, Benjamin Rolland, Craig Morgan, Guillaume Vaiva, Ali Amad
BACKGROUND: The role of migration as a risk factor remains unknown for mood disorders because of poor data. We sought to examine the prevalence and severity of mood disorders (bipolar disorder (BD), unipolar depressive disorder (UDD) and dysthymia) in first, second, and third generation migrants in France. METHODS: The Mental Health in the General Population survey interviewed 38,694 individuals. The prevalence of lifetime mood disorders, comorbidities, and clinical features was compared between migrants and non-migrants and by generation...
December 27, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28042822/enduring-sexually-dimorphic-impact-of-in-utero-exposure-to-elevated-levels-of-glucocorticoids-on-midbrain-dopaminergic-populations
#11
REVIEW
Glenda E Gillies, Kanwar Virdee, Ilse Pienaar, Felwah Al-Zaid, Jeffrey W Dalley
Glucocorticoid hormones (GCs) released from the fetal/maternal glands during late gestation are required for normal development of mammalian organs and tissues. Accordingly, synthetic glucocorticoids have proven to be invaluable in perinatal medicine where they are widely used to accelerate fetal lung maturation when there is risk of pre-term birth and to promote infant survival. However, clinical and pre-clinical studies have demonstrated that inappropriate exposure of the developing brain to elevated levels of GCs, either as a result of clinical over-use or after stress-induced activation of the fetal/maternal adrenal cortex, is linked with significant effects on brain structure, neurological function and behaviour in later life...
December 30, 2016: Brain Sciences
https://www.readbyqxmd.com/read/28042661/associations-between-early-maternal-depressive-symptom-trajectories-and-toddlers-felt-security-at-18-months-are-boys-and-girls-at-differential-risk
#12
Marjorie Beeghly, Ty Partridge, Ed Tronick, Maria Muzik, Mahya Rahimian Mashhadi, Jordan L Boeve, Jessica L Irwin
The goal of this study was to evaluate whether there are sex differences in children's vulnerability to caregiving risk, as indexed by trajectories of maternal depressive symptoms assessed from 2 to 18 months' postpartum, and children's rated attachment security in toddlerhood, adjusting for maternal social support and demographic risk. Analyses utilized longitudinal data collected for 182 African American mother-child dyads from economically diverse backgrounds. Participants were recruited at the time of the child's birth and followed to 18 months' postpartum...
January 2017: Infant Mental Health Journal
https://www.readbyqxmd.com/read/28041985/associations-between-inflammation-related-biomarkers-and-depressive-symptoms-in-individuals-with-recently-diagnosed-type-1-and-type-2-diabetes
#13
Christian Herder, Jan-Felix Fürstos, Bettina Nowotny, Alexander Begun, Klaus Strassburger, Karsten Müssig, Julia Szendroedi, Andrea Icks, Michael Roden
Depressive disorders represent a frequent comorbidity of both type 1 (T1D) and type 2 diabetes (T2D). Inflammation-related processes have been implicated in the development of both diabetes and depression. This study aimed to investigate whether biomarkers of subclinical inflammation were associated with depressive symptoms in individuals with recently diagnosed diabetes and if such associations differed by diabetes type. This cross-sectional study was based on 295 individuals with T2D (67% men, mean age 53years) and 139 individuals with T1D (60% men, mean age 36years) of the German Diabetes Study...
December 29, 2016: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28041575/the-impact-of-major-depression-on-heart-rate-variability-and-endothelial-dysfunction-in-patients-with-stable-coronary-artery-disease
#14
Esra Aydin Sunbul, Murat Sunbul, Huseyin Gulec
BACKGROUND: Depression is an independent risk factor in cardiovascular diseases. Changes in the cardiac autonomic functions and pro-inflammatory processes are potential biological factors. Endothelial dysfunction plays an important role in the etiopathogenesis of atherosclerosis. Our objective was to evaluate the impact of major depression on heart rate variability and endothelial dysfunction in patients with stable CAD. METHODS: The study group included 65 CAD patients with a diagnosis of major depression and 54 CAD patients without major depression...
January 2017: General Hospital Psychiatry
https://www.readbyqxmd.com/read/28040745/does-job-promotion-affect-men-s-and-women-s-health-differently-dynamic-panel-models-with-fixed-effects
#15
Anna Nyberg, Paraskevi Peristera, Hugo Westerlund, Gunn Johansson, Linda L Magnusson Hanson
BACKGROUND: Higher occupational status has consistently been shown to be associated with better health, but few studies have to date examined if an upward change in occupational status is associated with a positive change in health. Furthermore, very little is known about whether this association differs by sex. METHODS: Data were derived from four waves (2008-14) of the Swedish Longitudinal Occupational Survey of Health (SLOSH), a follow-up study of a nationally representative sample of the Swedish working population...
December 31, 2016: International Journal of Epidemiology
https://www.readbyqxmd.com/read/28040450/cortical-inhibitory-and-excitatory-function-in-drug-naive-generalized-anxiety-disorder
#16
Cheng-Ta Li, Chia-Feng Lu, Hui-Ching Lin, Ying-Zu Huang, Chi-Hung Juan, Tung-Ping Su, Ya-Mei Bai, Mu-Hong Chen, Wei-Chen Lin
BACKGROUND: A growing body of evidence suggests that deficits in GABAergic inhibitory and glutamatergic excitatory neurotransmission may be involved in the core pathophysiology of generalized anxiety disorder (GAD), a disease characterized by pathological anxious worrying. The aim of the present study was to measure motor cortical excitability by paired-pulse transcranial magnetic stimulation (ppTMS) in patients with GAD. METHODS: ppTMS measurements of excitation and inhibition from bilateral motor cortices were investigated in 26 right-handed GAD patients who were drug-naïve (half of them with a comorbidity of major depressive disorder) and 35 right-handed age- and sex-matched healthy controls...
December 21, 2016: Brain Stimulation
https://www.readbyqxmd.com/read/28039796/vertex-wise-examination-of-depressive-symptom-dimensions-and-brain-volumes-in-older-adults
#17
Molly E McLaren, Sarah M Szymkowicz, Andrew O'Shea, Adam J Woods, Stephen D Anton, Vonetta M Dotson
Differences in brain volumes have commonly been reported in older adults with both subthreshold and major depression. Few studies have examined the association between specific symptom dimensions of depression and brain volumes. This study used vertex-wise analyses to examine the association between specific symptom dimensions of depression and brain volumes in older adults with subthreshold levels of depressive symptoms. Forty-three community-dwelling adults between the ages of 55 and 81 years underwent a structural Magnetic Resonance Imaging scan and completed the Center for Epidemiologic Studies Depression Scale (CES-D)...
December 16, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/28039531/stress-and-psychopathology-and-its-impact-on-quality-of-life-in-chronic-anal-fissure-caf-patients
#18
Özden Arısoy, Neriman Şengül, Affan Çakir
BACKGROUND: Chronic anal fissure (CAF) onset, exacerbation, and impact on quality of life are influenced by a host of psychological, physiological, and social factors. We aimed to investigate the difference in psychopathology and stress between normal and CAF groups. METHODS: Thirty CAF patients and 20 age-sex matched healthy controls were evaluated for Axis I psychopathology, depression, anxiety, and stress with Hamilton and Hospital Depression-Anxiety Scales, Perceived Stress Scale, and SF-36...
December 30, 2016: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28038812/hopelessness-among-adults-with-congenital-heart-disease-cause-for-despair-or-hope
#19
Bahareh Eslami, Adrienne H Kovacs, Philip Moons, Kyomars Abbasi, Jamie L Jackson
BACKGROUND: Adults with congenital heart disease (CHD) face unique life courses and challenges that may negatively influence their psychological functioning. The aims of this study were to (1) examine the level of hopelessness among adults with CHD in comparison with non-CHD participants and (2) identify correlates of elevated hopelessness among adults with CHD. METHODS: We enrolled 347 patients with CHD (18-64years, 52.2% female) and 353 matched (by sex/age) non-CHD persons in this cross-sectional study...
December 21, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/28038403/higher-serum-dhea-concentrations-before-and-after-ssri-treatment-are-associated-with-remission-of-major-depression
#20
Christina M Hough, Daniel Lindqvist, Elissa S Epel, Molly St Denis, Victor I Reus, F Saverio Bersani, Rebecca Rosser, Laura Mahan, Heather M Burke, Owen M Wolkowitz, Synthia H Mellon
BACKGROUND: Dehydroepiandrosterone (DHEA) and its sulfated ester DHEA-sulfate (DHEA-S), (together DHEA[S]), are the most abundant adrenal steroids in humans and are found in blood and the brain, where they function as neurosteroids with direct receptor affinities. Preclinical studies suggest that DHEA(S) has antidepressant/neuroprotective properties, and exogenously administered DHEA has shown antidepressant efficacy in humans. Nonetheless, the role of endogenous DHEA(S) levels in major depressive disorder (MDD) and antidepressant outcomes remains unclear...
December 5, 2016: Psychoneuroendocrinology
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