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Sex differences, depression

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https://www.readbyqxmd.com/read/29352386/glucose-homeostasis-in-major-depression-and-schizophrenia-a-comparison-among-drug-na%C3%A3-ve-first-episode-patients
#1
Johann Steiner, Brisa S Fernandes, Paul C Guest, Henrik Dobrowolny, Gabriela Meyer-Lotz, Sabine Westphal, Katrin Borucki, Kolja Schiltz, Zoltán Sarnyai, Hans-Gert Bernstein
There is evidence for insulin resistance in drug-naïve first-episode schizophrenia (Sz) patients. We have tested whether impaired insulin homeostasis is also present in first-episode patients with major depression (MD) and if this can be discerned from stress-related and medication effects. Homeostatic model assessment of insulin resistance (HOMA-IR) was determined in a cross-sectional cohort study of acute first-episode drug-naïve patients with MD (n = 18) or Sz (n = 24), and healthy controls (C, n = 43)...
January 19, 2018: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/29352280/leisure-time-physical-activity-and-prevalence-of-non-communicable-pathologies-and-prescription-medication-in-spain
#2
Pablo Fernandez-Navarro, María Teresa Aragones, Victoria Ley
Our aims were to describe physical activity (PA) behaviour in Spain and to examine its association with the prevalence of some of the major non-communicable diseases and with the use of prescription medication. Individualized secondary data retrieved from the 2014 European Health Interview Survey (EHIS) for Spain were used to conduct a cross-sectional epidemiological study (n = 18926). PA was assessed by two different measures: a specific designed variable for EHIS and a leisure time PA frequency-based query of the national survey...
2018: PloS One
https://www.readbyqxmd.com/read/29349245/mental-health-of-sub-saharan-african-migrants-the-gendered-role-of-migration-paths-and-transnational-ties
#3
Julie Pannetier, France Lert, Marie Jauffret Roustide, Annabel Desgrées du Loû
In Europe, migrants are at higher risk of common mental disorders or psychological distress than are natives. Little is known regarding the social determinants of migrant mental health, particularly the roles played by migration conditions and transnational practices, which may manifest themselves in different ways for men and for women. The goal of this paper was to understand the gendered roles of migration paths and transnational ties in mental health among sub-Saharan African migrants residing in the Paris, France, metropolitan area...
December 2017: SSM—Population Health
https://www.readbyqxmd.com/read/29338774/depressive-symptoms-are-associated-with-poor-glycemic-control-among-women-with-type-2-diabetes-mellitus
#4
Carlos Góis, Tiago Antunes Duarte, Sofia Paulino, João Filipe Raposo, Isabel do Carmo, António Barbosa
OBJECTIVE: In patients with type 2 diabetes mellitus, depressive symptoms may be associated with metabolic deterioration. The impact of sex on this association is unclear. The aim of this study is to analyze the relationship between depression and metabolic control by sex. The data presented is the side product of the clinical investigation by Rui Duarte, MD, Treatment Response in Type 2 Diabetes Patients with Major Depression from 2007. RESULTS: A sample of 628 outpatients with type 2 diabetes mellitus was taken from a specialized diabetes outpatient clinic...
January 16, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29337907/few-sex-differences-in-hospitalized-suicide-attempters-aged-70-and-above
#5
Stefan Wiktorsson, Therese Rydberg Sterner, Madeleine Mellqvist Fässberg, Ingmar Skoog, Anne Ingeborg Berg, Paul Duberstein, Kimberly Van Orden, Margda Waern
Relatively little research attention has been paid to sex issues in late life suicidal behaviour. The aim was to compare clinical characteristics of women and men aged 70+ who were hospitalized after a suicide attempt. We hypothesized higher depression and anxiety scores in women, and we expected to find that men would more often attribute the attempt to health problems and compromised autonomy. Participants (56 women and 47 men, mean age 80) were interviewed by a psychologist. In addition to psychiatric and somatic health assessments, participants responded to an open-ended question concerning attributions of the attempt...
January 16, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29337847/hiv-care-continuum-disparities-among-bisexual-black-men-and-the-mediating-effect-of-psychosocial-co-morbidities
#6
M Reuel Friedman, Jordan M Sang, Leigh A Bukowski, Derrick D Matthews, Lisa A Eaton, H Fisher Raymond, Ron Stall
INTRODUCTION: Differences across the HIV care continuum between men who have sex with men and women (MSMW) and men who have sex with men only (MSMO) are emerging in recent literature but have not been comprehensively documented among Black MSM. Although MSMW have lower HIV prevalence than MSMO, they are more likely to be HIV-positive unaware and be virally unsuppressed. Explanatory factors for these differences have not previously been assessed. METHODS: Between 2014-2016, we surveyed sexually active Black MSM ≥18 years old at Black Gay Pride events in six U...
January 15, 2018: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/29337584/is-antidepressant-use-associated-with-difficulty-identifying-feelings-a-brief-report
#7
Jani Kajanoja, Noora M Scheinin, Max Karukivi, Linnea Karlsson, Hasse Karlsson
Studies on the subjective effects of antidepressants suggest that they may not only improve depressed mood, but as an adverse effect also cause "emotional blunting." This phenomenon is poorly understood and little studied. The aim of this study was to examine the association of serotonergic antidepressant use and subjective emotional awareness. Emotional awareness was assessed using the Difficulty Identifying Feelings subscale from the 20-Item Toronto Alexithymia Scale. Fifty-seven individuals on antidepressant medication and 441 controls were compared...
January 15, 2018: Experimental and Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29336857/identifying-risk-factors-for-the-development-of-stiffness-after-revision-total-knee-arthroplasty
#8
S B Dowdle, Nicholas A Bedard, Jessell M Owens, Yubo Gao, John J Callaghan
BACKGROUND: Although there are several studies concerning manipulation under anesthesia (MUA) after primary total knee arthroplasty, there is a paucity of literature evaluating MUA after revision total knee arthroplasty (rTKA). The purpose of this study was to determine the incidence, timing, and risk factors associated with MUA after rTKA. METHODS: The Humana database was reviewed from 2007 to 2015 for all patients who underwent rTKA. Patients who underwent rTKA followed by ipsilateral MUA were identified...
December 5, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29334499/cognitive-function-and-its-risk-factors-among-older-us-adults-living-at-home
#9
William Dale, Ashwin A Kotwal, Joseph W Shega, L Philip Schumm, David W Kern, Jayant M Pinto, Kelly M Pudelek, Linda J Waite, Martha K McClintock
BACKGROUND: The Montreal Cognitive Assessment (MoCA) has not been administered to a representative national sample, precluding comparison of patient scores to the general population and for risk factor identification. METHODS: A validated survey-based adaptation of the MoCA (MoCA-SA) was administered to a probability sample of home-dwelling US adults aged 62 to 90, using the National Social Life, Health, and Aging Project (n=3129), yielding estimates of prevalence in the United States...
January 12, 2018: Alzheimer Disease and Associated Disorders
https://www.readbyqxmd.com/read/29334035/neural-correlates-of-ostracism-in-transgender-persons-living-according-to-their-gender-identity-a-potential-risk-marker-for-psychopathology
#10
Sven C Mueller, Katrien Wierckx, Sara Boccadoro, Guy T'Sjoen
BACKGROUND: Stigmatization in society carries a high risk for development of psychopathology. Transgender persons are at particularly high risk for such stigmatization and social rejection by others. However, the neural correlates of ostracism in this group have not been captured. METHOD: Twenty transgender men (TM, female-to-male) and 19 transgender women (TW, male-to-female) already living in their gender identity and 20 cisgender men (CM) and 20 cisgender women (CW) completed a cyberball task assessing both exclusion and re-inclusion during functional magnetic resonance imaging (fMRI)...
January 15, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29332626/symptoms-of-depression-and-anxiety-and-11-year-all-cause-mortality-in-men-and-women-undergoing-coronary-artery-bypass-graft-cabg-surgery
#11
Galit Geulayov, Ilya Novikov, Daniella Dankner, Rachel Dankner
OBJECTIVES: To investigate the overall and the sex-specific association of preoperative and one-year post coronary artery bypass (CABG) surgery symptoms of depression and anxiety with 11-year all-cause mortality. METHODS: A multicenter prospective study including 1125 patients who completed the Hospital Anxiety and Depression Scale (HADS) before an elective CABG surgery, of whom 850 completed the HADS again at one-year follow-up. Information on all-cause mortality was obtained through the Israeli Ministry of Internal Affairs Register...
February 2018: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/29331929/sex-related-differential-response-to-dexamethasone-in-endocrine-and-immune-measures-in-depressed-in-patients-and-healthy-controls
#12
Carina Rampp, Andreas Eichelkraut, Johanna Best, Darina Czamara, Monika Rex-Haffner, Manfred Uhr, Elisabeth B Binder, Andreas Menke
Although sex differences in major depression have been reported repeatedly, the underlying mechanisms are still disputed. The rapidly changing gonadal steroid concentrations of the postpartum period or during menopause have been shown to be associated with depressive symptoms and to modulate the hypothalamic-pituitary-adrenal (HPA)-axis, which is implicated in depression. The sample comprised of 128 depressed in-patients (36.7% women) and 166 healthy controls (30.0% women). Blood was collected at baseline (at 6pm) and then 3 h as well as 21 h after ingestion of 1...
January 3, 2018: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29331706/the-association-between-adherence-and-outcome-in-an-internet-intervention-for-depression
#13
Kristina Fuhr, Johanna Schröder, Thomas Berger, Steffen Moritz, Björn Meyer, Wolfgang Lutz, Fritz Hohagen, Martin Hautzinger, Jan Philipp Klein
BACKGROUND: Adherence to Internet interventions is often reported to be rather low and this might adversely impact the effectiveness of these interventions. We investigated if patient characteristics are associated with adherence, and if adherence is associated with treatment outcome in a large RCT of an Internet intervention for depression, the EVIDENT trial. METHODS: Patients were randomized to either care as usual (CAU) or CAU plus the Internet intervention Deprexis...
December 27, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29331317/resting-state-quantitative-eeg-characteristics-of-insomniac-patients-with-depression
#14
Yunna Kwan, Chorom Baek, Sunhye Chung, Tae Hui Kim, Sungwon Choi
Insomnia is known to show hyperarousal in the central nervous system. However, depression that often coexists with insomnia exhibits hypo-activity in the frontal lobe, which is very different from insomnia. In the present study, we examined wake resting state EEG of insomniac patients with depression to investigate whether they could be conceptualized as spectrum of insomnia or significantly different from insomnia. We compared the absolute power values of EEG spectra of three groups: 15 insomniacs with comorbid depression (CD), age- and sex-matched 15 comorbid-free insomniacs (CFI), and 15 good sleep controls (GSC)...
January 10, 2018: International Journal of Psychophysiology
https://www.readbyqxmd.com/read/29329063/seasonality-of-depressive-symptoms-in-women-but-not-in-men-a-cross-sectional-study-in-the-uk-biobank-cohort
#15
Laura M Lyall, Cathy A Wyse, Carlos A Celis-Morales, Donald M Lyall, Breda Cullen, Daniel Mackay, Joey Ward, Nicholas Graham, Rona J Strawbridge, Jason M R Gill, Amy Ferguson, Mark E S Bailey, Jill P Pell, Annie M Curtis, Daniel J Smith
BACKGROUND: We examined whether seasonal variations in depressive symptoms occurred independently of demographic and lifestyle factors, and were related to change in day length and/or outdoor temperature. METHODS: In a cross-sectional analysis of >150,000 participants of the UK Biobank cohort, we used the cosinor method to assess evidence of seasonality of a total depressive symptoms score and of low mood, anhedonia, tenseness and tiredness scores in women and men...
January 4, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29327213/add-on-treatment-with-curcumin-has-antidepressive-effects-in-thai-patients-with-major-depression-results-of-a-randomized-double-blind-placebo-controlled-study
#16
Buranee Kanchanatawan, Sookjaroen Tangwongchai, Atapol Sughondhabhirom, Siriluck Suppapitiporn, Solaphat Hemrunrojn, André F Carvalho, Michael Maes
Activation of immune-inflammatory and oxidative-nitrosative (IO&NS) stress pathways plays a role in major depression (MDD). Evidence suggests that curcumin (500-1000 mg/day), a polyphenol with strong anti-IO&NS properties, may have efficacy either as monotherapy or as an adjunctive treatment for depression. Further controlled trials with extended treatment periods (> 8 weeks) and higher curcumin doses are warranted. This 12-week study was carried out to examine the effects of adjunctive curcumin for the treatment of MDD...
January 11, 2018: Neurotoxicity Research
https://www.readbyqxmd.com/read/29321530/the-effect-of-raloxifene-augmentation-in-men-and-women-with-a-schizophrenia-spectrum-disorder-a-systematic-review-and-meta-analysis
#17
REVIEW
Janna de Boer, Merel Prikken, Wan U Lei, Marieke Begemann, Iris Sommer
Recognizing the robust sex differences in schizophrenia prevalence, the selective estrogen receptor modulator (SERM) raloxifene is a likely candidate for augmentation therapy in this disorder. Therefore, a systematic search was performed using PubMed (Medline), Embase, PsychInfo, and Cochrane Database of Systematic Reviews. Randomized controlled trials investigating the effect of raloxifene in schizophrenia spectrum disorders were included in the quantitative analyses. Outcome measures were psychotic symptom severity, depression, and cognition...
January 10, 2018: NPJ Schizophrenia
https://www.readbyqxmd.com/read/29320669/comorbidities-in-australian-women-with-hormone-dependent-breast-cancer-a-population-based-analysis
#18
Huah Shin Ng, Bogda Koczwara, David M Roder, Theo Niyonsenga, Agnes I Vitry
OBJECTIVE: To compare how frequently selected chronic diseases developed in women with breast cancer receiving endocrine therapy, and in women without cancer. DESIGN, SETTING AND PARTICIPANTS: Retrospective, rolling cohort study, analysing a random 10% sample of Pharmaceutical Benefits Scheme (PBS) data for the period 1 January 2003 - 31 December 2014. Women with breast cancer who first commenced endocrine therapy between January 2004 and December 2011 were identified, and age- and sex-matched (1:10) by comorbidity with control groups of women who did not have a dispensing record for antineoplastic agents during the study period or the comorbidity of interest at baseline...
January 15, 2018: Medical Journal of Australia
https://www.readbyqxmd.com/read/29317602/genome-wide-meta-analyses-of-stratified-depression-in-generation-scotland-and-uk-biobank
#19
Lynsey S Hall, Mark J Adams, Aleix Arnau-Soler, Toni-Kim Clarke, David M Howard, Yanni Zeng, Gail Davies, Saskia P Hagenaars, Ana Maria Fernandez-Pujals, Jude Gibson, Eleanor M Wigmore, Thibaud S Boutin, Caroline Hayward, Generation Scotland, David J Porteous, Ian J Deary, Pippa A Thomson, Chris S Haley, Andrew M McIntosh
Few replicable genetic associations for Major Depressive Disorder (MDD) have been identified. Recent studies of MDD have identified common risk variants by using a broader phenotype definition in very large samples, or by reducing phenotypic and ancestral heterogeneity. We sought to ascertain whether it is more informative to maximize the sample size using data from all available cases and controls, or to use a sex or recurrent stratified subset of affected individuals. To test this, we compared heritability estimates, genetic correlation with other traits, variance explained by MDD polygenic score, and variants identified by genome-wide meta-analysis for broad and narrow MDD classifications in two large British cohorts - Generation Scotland and UK Biobank...
January 10, 2018: Translational Psychiatry
https://www.readbyqxmd.com/read/29316846/acute-stress-evokes-sexually-dimorphic-stressor-specific-patterns-of-neural-activation-across-multiple-limbic-brain-regions-in-adult-rats
#20
Ankit Sood, Karina Chaudhari, Vidita A Vaidya
Stress enhances the risk for psychiatric disorders such as anxiety and depression. Stress responses vary across sex and may underlie the heightened vulnerability to psychopathology in females. Here, we examined the influence of acute immobilization stress (AIS) and a two-day short-term forced swim stress (FS) on neural activation in multiple cortical and subcortical brain regions, implicated as targets of stress and in the regulation of neuroendocrine stress responses, in male and female rats using Fos as a neural activity marker...
January 10, 2018: Stress: the International Journal on the Biology of Stress
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