Yi-Bang Cheng, Lutgarde Thijs, Lucas S Aparicio, Qi-Fang Huang, Fang-Fei Wei, Yu-Ling Yu, Jessica Barochiner, Chang-Sheng Sheng, Wen-Yi Yang, Teemu J Niiranen, José Boggia, Zhen-Yu Zhang, Katarzyna Stolarz-Skrzypek, Natasza Gilis-Malinowska, Valérie Tikhonoff, Wiktoria Wojciechowska, Edoardo Casiglia, Krzysztof Narkiewicz, Jan Filipovský, Kalina Kawecka-Jaszcz, Ji-Guang Wang, Yan Li, Jan A Staessen
OBJECTIVE: Whether cardiovascular risk is more tightly associated with central (cSBP) than brachial (bSBP) systolic pressure remains debated, because of their close correlation and uncertain thresholds to differentiate cSBP into normotension vs hypertension. DESIGN AND METHOD: In a person-level meta-analysis of the International Database of Central Arterial Properties for Risk Stratification (n = 5576; 54.1% women; mean age 54.2 years), outcome-driven thresholds for cSBP were determined and whether the cross-classification of cSBP and bSBP improved risk stratification was explored...
June 1, 2022: Journal of Hypertension