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Tricks of the trade

Rabia Zeeshan, Zeeshan Mutahir
Decades of cancer research have unraveled genetic, epigenetic and molecular pathways leading to plausible therapeutic targets; many of which hold great promise in improving clinical outcomes. Metastatic tumors become evident early on and are one of the major causes of cancer-related fatalities worldwide. This review depicts the sequential events of cancer metastasis. Genetic and epigenetic heterogeneity influences local tumor cell invasion, intravasation, survival in circulation, extravasation and colonization to distant sites...
March 9, 2017: Bosnian Journal of Basic Medical Sciences
Daniel W Skupski, Alessandro Ghidini
No abstract text is available yet for this article.
September 2016: Birth
A Russell Moore
General principles and techniques for collection, preparation, and staining of cytologic samples in the general practice setting are reviewed. Tips for collection of digital images are also discussed.
January 2017: Veterinary Clinics of North America. Small Animal Practice
Amar Shaikhouni, Jeffrey R Leonard
No abstract text is available yet for this article.
May 27, 2016: Journal of Child Neurology
Ileana Chinnici, Paolo Brenni
A manuscript by Georg and Sigmund Merz dated 1862 and containing instructions for assembling the equatorial telescope acquired by the Palermo Observatory is conserved in the archives of the Museo Astronomico e Copernicano in Rome. It is a rare document that reveals "tricks of the trade" and technical knowledge not usually included in textbooks or treatises. It was sent to the Palermo Observatory as an aid to the installation of the telescope, which made a signal contribution to the development of solar physics in Italy in the 19th century...
2015: Nuncius
Kivanc Derya Peker, Alpen Yahya Gumusoglu, Hakan Seyit, Hamit Ahmet Kabuli, Aysun Erbahceci Salik, Murat Gonenc, Selin Kapan, Halil Alis
BACKGROUND: The presence of postoperative bile leak is the major outcome measure for the assessment of operative success in partial cystectomy for hydatid liver disease. However, the optimal operative strategy to reduce the postoperative bile leak rate is yet to be defined. METHODS: Medical records of patients who underwent partial cystectomy for hydatid liver disease between January 2013 and January 2015 were reviewed in this retrospective analysis. All patients were managed with a specific operative protocol...
December 2015: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
Hester J Scheffer, Marleen C A M Melenhorst, Ana M Echenique, Karin Nielsen, Aukje A J M van Tilborg, Willemien van den Bos, Laurien G P H Vroomen, Petrousjka M P van den Tol, Martijn R Meijerink
Image-guided tumor ablation techniques have significantly broadened the treatment possibilities for primary and secondary hepatic malignancies. A new ablation technique, irreversible electroporation (IRE), was recently added to the treatment armamentarium. As opposed to thermal ablation, cell death with IRE is primarily induced using electrical energy: electrical pulses disrupt the cellular membrane integrity, resulting in cell death while sparing the extracellular matrix of sensitive structures such as the bile ducts, blood vessels, and bowel wall...
September 2015: Techniques in Vascular and Interventional Radiology
Donna R Whelan, Toby D M Bell
Application of single-molecule fluorescence detection has led to the development of light microscopy techniques that make it possible to study fluorescent samples at spatial resolutions significantly improved upon the diffraction limit of light. The biological and materials science applications of these "super-resolution" microscopy methods are vast, causing current demand for them to be high. However, implementation, execution, and interpretation of these techniques, particularly involving biological samples, require a broad interdisciplinary skillset, not often found in a single laboratory...
February 5, 2015: Journal of Physical Chemistry Letters
Massimo Galia, Francesco Agnello, Ludovico La Grutta, Giuseppe Lo Re, Giuseppe Cabibbo, Emanuele Grassedonio, Bruno Giuseppe Gioia, Gianvincenzo Sparacia, Antonio Lo Casto, Roberto Lagalla, Massimo Midiri
Bowel obstruction (BO) is a frequent cause of hospitalization and surgical consultation for acute abdominal pain. It is usually suspected at physical examination, but clinical and laboratory data are often nonspecific. Thus, computed tomography plays a crucial role in a correct diagnosis of BO. Indeed, computed tomography can confirm a diagnosis of BO, and identify the location and cause of the obstruction. In this review, the computed tomography appearances of common and uncommon causes of BO and pseudo-obstruction are reviewed...
2015: Expert Review of Gastroenterology & Hepatology
Ibhar Al Mheid, Salim Hayek, Arshed A Quyyumi
No abstract text is available yet for this article.
June 2015: JACC. Cardiovascular Interventions
Victor Benno Meyer-Rochow, Karsing Megu, Jharna Chakravorty
BACKGROUND: Since outside the tribal areas of North-East India it is not widely known, neither in the world nor in India itself, that rats are considered a delicious food item, this was one of several reasons why we decided to present this ethnographic account of rat procurement and preparation (together with some additional comments on the cultural role that rats have especially amongst members of the Adi tribe). Consumption of rats by humans as a biological control method far superior to the use of rodenticide poisoning and rat consumption as a way to reduce hunting pressure on rare wild animals were further considerations to publish this account...
2015: Journal of Ethnobiology and Ethnomedicine
Padraig Ó Lúanaigh
This research was undertaken to understand the influence of registered nurses on nursing students' learning in the clinical environment to inform strategies to enable registered nurses to provide effective support to learners while also assisting nursing students to adopt approaches to maximise their learning in the clinical environment. A case study approach was applied in this research to explore descriptions of clinical experience of five final year nursing students. The student participants identified the importance of the clinical environment to their learning and wanted to and had actively managed their learning in the clinical environment...
November 2015: Nurse Education in Practice
Jan F Gielis, Wolfgang Jungraithmayr, Gaëlle A Boulet, John Paul Bogers, Walter Weder, Paul Cos, Paul E Y Van Schil
BACKGROUND: Pulmonary ischemia-reperfusion injury (IRI) causes postoperative morbidity in patients undergoing lung transplantation, isolated lung perfusion, and cardiopulmonary bypass and may lead to potentially lethal pathologies such as respiratory shock. In-depth study of this pathology requires a reliable animal model. Mice are a popular species to develop experimental models because of their logistic advantages and the availability of knock outs. However, their small size warrants microsurgical techniques and a skilled surgeon...
April 2015: Journal of Surgical Research
Anwesha Goswami, Steven G Van Lanen
Amide bond-containing (ABC) biomolecules are some of the most intriguing and functionally significant natural products with unmatched utility in medicine, agriculture and biotechnology. The enzymatic formation of an amide bond is therefore a particularly interesting platform for engineering the synthesis of structurally diverse natural and unnatural ABC molecules for applications in drug discovery and molecular design. As such, efforts to unravel the mechanisms involved in carboxylate activation and substrate selection has led to the characterization of a number of structurally and functionally distinct protein families involved in amide bond synthesis...
February 2015: Molecular BioSystems
Naruhiko Ikoma, Osamu Itano, Go Oshima, Yuko Kitagawa
Laparoscopic liver resection is gaining popularity because of the availability of new laparoscopic instruments and advanced techniques. Laparoscopic liver mobilization is not only necessary for pure laparoscopic liver resection but also for laparoscopy-assisted hepatectomy. Laparoscopy-assisted hepatectomy significantly reduces the length of the laparotomy incision, and it is a good educational transition to the more advanced laparoscopic liver resection. Laparoscopic liver mobilization is a simple and easy procedure if surgeons know what challenges to expect...
February 2015: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
Gloria Lemay
No abstract text is available yet for this article.
2014: Midwifery Today with International Midwife
Anders Albåge, Lena Jidéus, Hans Lidén, Henrik Scherstén
In the Cox-Maze IV procedure, or in endocardial left atrial ablation, correct positioning of the surgical ablation probe within the left atrium might be difficult due to bulging or folds in the posterior left atrial wall. The Berglin apical stitch is a simple trick of the trade to create a smooth surface in the posterior left atrium that facilitates performing a safe transmural lesion and, consequently, may increase antiarrhythmic efficiency.
October 2014: Interactive Cardiovascular and Thoracic Surgery
Marguerite DeLiema, Yongjie Yon, Kathleen H Wilber
PURPOSE OF THE STUDY: Financial fraud is estimated to cost consumers approximately $50 billion annually. To examine how new hires are trained to engage in fraud, this study analyzed a sales training transcript from Alliance for Mature Americans (Alliance). In 1996, Alliance was charged with using deception and misrepresentation to sell more than $200 million worth of living trusts and annuities to 10,000 older adults in California. DESIGN AND METHODS: Transcribed recordings from a 2-day Alliance sales training seminar were analyzed using NVivo10, coded inductively, and examined to identify emergent themes...
April 2016: Gerontologist
Stephen J Simpson, David Raubenheimer
No abstract text is available yet for this article.
April 17, 2014: Nature
T H Yilmaz, T Evers, M Sussman, P Vassiliu, E Degiannis, D Doll
BACKGROUND AND AIMS: Patients with penetrating trauma of the major vessels of the chest are infrequently encountered. This is due to the fact that the majority of these patients die on scene, as well as due to the overall dramatic decline in the incidence of penetrating trauma in the Western world. A certain proportion of survivors are physiologically stable and can be transferred to adequate care. Patients who are physiologically unstable must be dealt with by the surgeons available without delay...
September 2014: Scandinavian Journal of Surgery: SJS
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