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https://www.readbyqxmd.com/read/29351642/caregiver-provided-physical-therapy-home-programs-for-children-with-motor-delay-a-scoping-review
#1
Edward James R Gorgon
Background: Caregiver-provided physical therapy home programs (PTHP) play an important role in enhancing motor outcomes in pediatric patient populations. Purpose: This scoping review systematically mapped clinical trials of caregiver-provided PTHP that were aimed at enhancing motor outcomes in children who have or who are at risk for motor delay, with the purpose of (1) describing trial characteristics; (2) assessing methodologic quality, and (3) examining the reporting of caregiver-related components...
January 17, 2018: Physical Therapy
https://www.readbyqxmd.com/read/29351637/prospective-multicenter-assessment-of-all-cause-mortality-following-surgery-for-adult-cervical-deformity
#2
Justin S Smith, Christopher I Shaffrey, Han Jo Kim, Peter Passias, Themistocles Protopsaltis, Renaud Lafage, Gregory M Mundis, Eric Klineberg, Virginie Lafage, Frank J Schwab, Justin K Scheer, Emily Miller, Michael Kelly, D Kojo Hamilton, Munish Gupta, Vedat Deviren, Richard Hostin, Todd Albert, K Daniel Riew, Robert Hart, Doug Burton, Shay Bess, Christopher P Ames
BACKGROUND: Surgical treatments for adult cervical spinal deformity (ACSD) are often complex and have high complication rates. OBJECTIVE: To assess all-cause mortality following ACSD surgery. METHODS: ACSD patients presenting for surgical treatment were identified from a prospectively collected multicenter database. Clinical and surgical parameters and all-cause mortality were assessed. RESULTS: Of 123 ACSD patients, 120 (98%) had complete baseline data (mean age, 60...
January 17, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29351635/reversibility-of-severe-mitral-valve-regurgitation-after-left-ventricular-assist-device-implantation-single-centre-observations-from-a-real-life-population-of-patients
#3
Monica Dobrovie, Ricardo A Spampinato, Elena Efimova, Jaqueline G da Rocha E Silva, Julia Fischer, Michael Kuehl, Jens-Uwe Voigt, Ann Belmans, Agnieszka Ciarka, Fernanda Bonamigo Thome, Valerie Schloma, Yaroslava Dmitrieva, Sven Lehmann, Jochen Hahn, Elfriede Strotdrees, Friedrich-Wilhelm Mohr, Jens Garbade, Anna L Meyer
OBJECTIVES: This study evaluates the impact of untreated preoperative severe mitral valve regurgitation (MR) on outcomes after left ventricular assist device (LVAD) implantation. METHODS: Of the 234 patients who received LVAD therapy in our centre during a 6-year period, we selected those who had echocardiographic images of good quality and excluded those who underwent mitral valve replacement prior to or mitral valve repair during LVAD placement. The 128 patients selected were divided into 2 groups: Group A with severe MR (n = 65) and Group B with none to moderate MR (n = 63, 28 with moderate MR)...
January 16, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29351570/joint-adolescent-adult-early-phase-clinical-trials-to-improve-access-to-new-drugs-for-adolescents-with-cancer-proposals-from-the-multi-stakeholder-platform-accelerate
#4
N Gaspar, L V Marshall, D Binner, R Herold, R Rousseau, P Blanc, R Capdeville, J Carleer, C Copland, Y Kerloeguen, K Norga, L Pacaud, M-A Sevaux, C Spadoni, J Sterba, F Ligas, T Taube, M Uttenreuther-Fischer, S Chioato, M A O'Connell, B Geoerger, J-Y Blay, J C Soria, S Kaye, B Wulff, L Brugières, G Vassal, A D J Pearson
The impressive progress recently observed in adult cancers through the introduction of new drugs has not yet been translated to adolescents between 12 and 17 years of age. Currently adolescents are grouped with children, so their access to new, effective drugs already available for adults is delayed because paediatric drug development starts late relative to adult programmes. Moreover, specific early phase trials designed exclusively for adolescents in rare diseases recruit poorly, even if conducted internationally...
January 16, 2018: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/29351551/periodontal-health-status-and-lung-function-in-two-norwegian-cohorts
#5
Antonio Manuel Pérez Barrionuevo, Francisco Gómez Real, Jannicke Igland, Ane Johannessen, Ernst Omenaas, Karl A Franklin, Laura Pérez Barrionuevo, Anne Nordrehaug Åstrøm, Cecilie Svanes, Randi Jacobsen Bertelsen
RATIONALE AND OBJECTIVES: The oral cavity is united with the airways, and thus poor oral health may affect respiratory health. However, data on the interaction of periodontal and respiratory health is limited. We aimed to evaluate whether periodontal health status, assessed by the Community Periodontal Index (CPI), was related to lung function among young and middle-aged adults in two Norwegian cohorts. METHODS: Periodontal health status and lung function were measured among 656 participants in the Norwegian part of the European Community Respiratory Health Survey (ECHRS III) and the RHINESSA offspring study...
2018: PloS One
https://www.readbyqxmd.com/read/29351495/implementing-prehospital-evidence-based-guidelines-a-systematic-literature-review
#6
Jennifer N Fishe, Remle P Crowe, Rebecca E Cash, Nikiah G Nudell, Christian Martin-Gill, Christopher T Richards
OBJECTIVE: As prehospital research advances, more evidence-based guidelines (EBGs) are implemented into emergency medical services (EMS) practice. However, incomplete or suboptimal prehospital EBG implementation may hinder improvement in patient outcomes. To inform future efforts, this study's objective was to review existing evidence pertaining to prehospital EBG implementation methods. METHODS: This study was a systematic literature review and evaluation following the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) methodology...
January 19, 2018: Prehospital Emergency Care
https://www.readbyqxmd.com/read/29351262/imu-to-segment-assignment-and-orientation-alignment-for-the-lower-body-using-deep-learning
#7
Tobias Zimmermann, Bertram Taetz, Gabriele Bleser
Human body motion analysis based on wearable inertial measurement units (IMUs) receives a lot of attention from both the research community and the and industrial community. This is due to the significant role in, for instance, mobile health systems, sports and human computer interaction. In sensor based activity recognition, one of the major issues for obtaining reliable results is the sensor placement/assignment on the body. For inertial motion capture (joint kinematics estimation) and analysis, the IMU-to-segment (I2S) assignment and alignment are central issues to obtain biomechanical joint angles...
January 19, 2018: Sensors
https://www.readbyqxmd.com/read/29351234/contribution-of-the-ratio-of-tocopherol-homologs-to-the-oxidative-stability-of-commercial-vegetable-oils
#8
Mathias Zaunschirm, Marc Pignitter, Julia Kienesberger, Natalie Hernler, Christoph Riegger, Manfred Eggersdorfer, Veronika Somoza
The antioxidant activity of tocopherols in vegetable oils was shown to chiefly depend on the amount and the tocopherol homolog present. However, the most effective ratio of tocopherol homologs with regard to the antioxidant capacity has not been elucidated so far. The present study analyzed the effect of different tocopherol concentrations, homologs and ratios of homologs on markers of lipid oxidation in the most commonly consumed vegetable oils (canola, sunflower, soybean oil) stored in a 12 h light/dark cycle at 22 ± 2 °C for 56 days under retail/household conditions...
January 19, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29351154/predictors-of-health-related-quality-of-life-in-irritable-bowel-syndrome-patients-compared-with-healthy-individuals
#9
Raymond Addante, Bruce Naliboff, Wendy Shih, Angela P Presson, Kirsten Tillisch, Emeran A Mayer, Lin Chang
BACKGROUND: Irritable bowel syndrome (IBS) reduces health-related quality of life (HRQOL). It is unclear how having IBS modifies the impact of gastrointestinal (GI), psychosocial, and somatic symptom variables on HRQOL compared with healthy controls (HCs). AIMS: (1) Determine psychosocial, somatic, and physical status variables most predictive of HRQOL in IBS and HCs and (2) determine if IBS status modifies relationships between predictive factors and HRQOL. METHODS: IBS patients and HCs completed validated questionnaires measuring GI symptoms, psychosocial/somatic variables, and physical [physical component score (PCS)] and mental [mental component score (MCS)] HRQOL via the Short-Form-36...
January 18, 2018: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29351076/parasites-in-stray-dogs-from-italy-prevalence-risk-factors-and-management-concerns
#10
Claudio De Liberato, Federica Berrilli, Livio Odorizi, Roberto Scarcella, Marco Barni, Cristina Amoruso, Alessia Scarito, Margherita Montalbano Di Filippo, Andrea Carvelli, Francesca Iacoponi, Paola Scaramozzino
Parasites are among the most common pathogens recorded in dogs. High prevalence rates are usually reported in stray and shelter dogs, as these animals are less likely to be tested and treated. In this study a survey was carried out on intestinal and lung parasites of stray dogs at the moment of the admission in a shelter in Central Italy. In the period June 2014-June 2015, 262 individual faecal samples were examined. Twelve parasitic taxa were detected. Helminths were more prevalent than protozoa (61.8% and 25...
March 26, 2018: Acta Parasitologica
https://www.readbyqxmd.com/read/29350753/impact-of-relaxation-of-the-one-child-policy-on-maternal-mortality-in-guangzhou-china
#11
Wen Sun, Shiliang Liu, Fang He, Lili Du, Yanfang Guo, Darine El-Chaar, Shi Wu Wen, Dunjin Chen
OBJECTIVE: To assess the impact of the one-child policy in China on maternal mortality. METHODS: The present retrospective study included maternal death data from Guangdong, China, from January 1, 2006, to December 31, 2015; data from 2013 were excluded because they were not available. Maternal deaths were divided into legal and illegal pregnancies based on adherence to the one-child policy. The maternal mortality ratio (MMR) was compared between the groups, temporal trends in the MMR were examined, and comparisons were made of the causes of death and access to maternity care...
January 19, 2018: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29350664/synovial-cysts-of-the-hip
#12
Andrea Angelini, Gabriele Zanotti, Antonio Berizzi, Guido Staffa, Elio Piccinini, Pietro Ruggieri
BACKGROUND: Synovial cysts of the hip are relatively rare lesions comparing to other joints. Patients are usually asymptomatic, but in some cases symptoms such as pain and/or compression of vessels or nerve could be present. Purpose of the study was to define clinical features and optimal management of synovial cyst of the hip joint through an accurate review of the literature. METHODS: We present three consecutive cases treated with three different therapeutic strategies: surgical excision, wait-and-see and needle aspiration...
January 16, 2018: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29350658/experience-of-oesophageal-atresia-management-in-a-tertiary-bangladeshi-hospital
#13
Md Kabirul Islam
OBJECTIVES: Background and aim: This study has been conducted to determine the clinical presentations and surgical outcome of patients with OA admitted in a tertiary level hospital in Bangladesh. METHODS: A prospective analysis was conducted for 32 patients with confirmed OA between July 2007 and June 2015. Of them surgical correction was done in 25 cases. The other 7, in whom surgery could not be done, were excluded from the study. RESULTS: Of the 25 cases, that had been operated, 15 were full term and 52% were more than 48 hours old...
January 16, 2018: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29350652/complications-associated-with-brachioplasty-a-literature-review
#14
Andrea Sisti, Roberto Cuomo, Luca Milonia, Juri Tassinari, Antonio Castagna, Antonio Castagna, Cesare Brandi, Luca Grimaldi, Carlo D'Aniello, Giuseppe Nisi
BACKGROUND: Paralleling the growth of bariatric surgery, the demand for post-bariatric body-contouring surgery is increasing. Weight loss is the main cause, although not the only one, that drives patients to arm lift surgery. Several surgical techniques have been proposed over the years. Our aim was to consider the complications and outcomes according to the performed technique, through a wide review of the literature. METHODS: A search on PubMed/Medline was performed using "brachioplasty", "upper arm lifting", and "techniques" as key words...
January 16, 2018: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29350570/benefits-of-laparoscopic-approach-for-resection-of-liver-tumors-in-cirrhotic-patients
#15
Fabien Le Roux, Lionel Rebibo, Cyril Cosse, Denis Chatelain, Eric Nguyen-Khac, Rachid Badaoui, Jean-Marc Regimbeau
INTRODUCTION: Liver resection in cirrhotic patients is associated with increased morbidity and mortality. The objective of this study was to compare short-term results of laparoscopic resection (LR) and open surgery (OS) for minor liver resection in patients with hepatocellular carcinoma (HCC) hepatocellularcarcinoma on nontumor cirrhotic liver (HCC/F4) and patients with colorectal cancer liver metastases (CRLMs) colorectal liver metastases on healthy liver (CRLM/F0). MATERIALS AND METHODS: Between January 2005 and December 2014, all patients undergoing liver resection (n = 754) were included in this study...
January 19, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29350170/atypical-lower-motor-neuron-disease-with-enlargement-of-nissl-substance-report-of-an-autopsy-case
#16
Masayuki Shintaku, Daita Kaneda, Kiyomitsu Oyanagi
The patient was an 81-year-old woman diagnosed with atypical motor neuron disease who died after a long clinical course (7.5 years without mechanical assistance of ventilation) characterized by lower motor neuron signs and symptoms. Upper motor neuron signs and cognitive impairment were not apparent. Autopsy demonstrated severe neuronal loss in the anterior horn of the spinal cord, and some of the remaining neurons showed enlargement of Nissl substance and apparent thickening of the nuclear envelopes. No Bunina bodies, skein-like inclusions, or structures immunoreactive for phosphorylated transactivation response DNA-binding protein 43 were found...
January 19, 2018: Clinical Neuropathology
https://www.readbyqxmd.com/read/29350097/paternal-perinatal-depression-assessed-by-the-edinburgh-postnatal-depression-scale-and-the-gotland-male-depression-scale-prevalence-and-possible-risk-factors
#17
Magdalena Carlberg, Maigun Edhborg, Lene Lindberg
Several studies have used the Edinburgh Postnatal Depression Scale (EPDS), developed to screen new mothers, also for new fathers. This study aimed to further contribute to this knowledge by comparing assessment of possible depression in fathers and associated demographic factors by the EPDS and the Gotland Male Depression Scale (GMDS), developed for "male" depression screening. The study compared EPDS score ≥10 and ≥12, corresponding to minor and major depression, respectively, in relation to GMDS score ≥13...
January 1, 2018: American Journal of Men's Health
https://www.readbyqxmd.com/read/29349937/changes-in-clinical-characteristics-of-patients-with-an-initial-diagnosis-of-prostate-cancer-in-korea-10-year-trends-reported-by-a-tertiary-center
#18
Ji Eun Heo, Hyun Kyu Ahn, Jinu Kim, Byung Ha Chung, Kwang Suk Lee
BACKGROUND: The Korea Central Cancer Registry reported that incidence rates of prostate cancer have not increased continuously. We used recent trends in the incidence of prostate cancer to generate a preliminary report of the Korean population with prostate cancer. METHODS: Patients initially diagnosed with prostate cancer by prostate biopsy from 2006 to 2015 at our tertiary center were selected. All patients were categorized according to age (< 65, 65-75, > 75 years), time period (2006-2010 vs...
February 5, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29349936/preeclampsia-increases-the-incidence-of-postpartum-cerebrovascular-disease-in-korean-population
#19
Yejin Park, Geum Joon Cho, Log Young Kim, Tae Seon Lee, Min Jeong Oh, Young Han Kim
BACKGROUND: Multiple studies have been reported regarding preeclampsia as a possible risk factor of cerebrovascular disease (CVD). However, the correlation of preeclampsia and CVD, whether it is a cause-effect relationship or they are sharing common predisposing condition, is not well understood. Therefore, the aim of this study was to investigate the association between the preeclampsia during pregnancy and development of postpartum CVD. METHODS: A total of 1,384,550 Korean women who had a delivery between January 1, 2010 and December 31, 2012, were enrolled...
February 5, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29349871/dsp30-and-interleukin-2-as-a-mitotic-stimulant-in-b-cell-disorders-including-those-with-a-low-disease-burden
#20
Karen A Dun, Louise A Riley, Giuseppe Diano, Leanne B Adams, Eleanor Chiu, Archna Sharma
Chromosome abnormalities detected during cytogenetic investigations for B-cell malignancy offer prognostic information that can have wide ranging clinical impacts on patients. These impacts may include monitoring frequency, treatment type and disease staging level. The use of the synthetic oligonucleotide DSP30 combined with interleukin 2 (IL2) has been described as an effective mitotic stimulant in B-cell disorders, predominantly in chronic lymphocytic leukaemia (CLL) but also a range of other B-cell malignancies...
January 19, 2018: Genes, Chromosomes & Cancer
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