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https://www.readbyqxmd.com/read/29054934/radiation-induced-dna-damage-in-operators-performing-endovascular-aortic-repair
#1
Tamer El-Sayed, Ashish S Patel, Jun S Cho, James A Kelly, Francesca E Ludwinski, Prakash Saha, Oliver T Lyons, Alberto Smith, Bijan Modarai
Background -Radiation exposure during fluoroscopically-guided interventions such as endovascular aortic repair (EVAR) is a growing concern for operators. This study aimed to measure DNA damage/repair markers in operators perfoming EVAR. Methods -Expression of the DNA damage/repair marker, gamma-H2AX (γ-H2AX) and DNA damage response (DDR) marker, phosphorylated ataxia telangiectasia mutated (pATM), were quantified in circulating lymphocytes in operators during the peri-operative period of endovascular (infra-renal [IEVAR], branched [BEVAR] and fenestrated [FEVAR]) and open aortic repair using flow cytometry...
October 20, 2017: Circulation
https://www.readbyqxmd.com/read/29019561/atorvastatin-can-prevent-hepatic-remote-reperfusion-injury
#2
Carlos Henrique Marques Dos Santos, Doroty Mesquita Dourado, Baldomero Antonio Kato da Silva, Henrique Budib Dorsa Pontes, Euler de Azevedo-Neto, Giovanna Serra da Cruz Vendas, Ian de Oliveira Chaves, João Victor Cunha Miranda
BACKGROUND: Some studies have shown that statins have a promising effect on protection against reperfusion injury. AIM: To evaluate the ability of ischemic postconditioning, statins and both associated to prevent or minimize reperfusion injury in the liver of rats subjected to ischemia and reperfusion by abdominal aorta clamping. METHOD: Were used 41 Wistar rats, which were distributed into five groups: ischemia and reperfusion (I/R), ischemic postcondictioning (IPC), postconditioning + statin (IPC+S), statin (S) and Sham...
July 2017: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/28978347/clinical-features-of-igg4-related-periaortitis-periarteritis-based-on-the-analysis-of-179-patients-with-igg4-related-disease-a-case-control-study
#3
Makiko Ozawa, Yasunari Fujinaga, Junpei Asano, Akira Nakamura, Takayuki Watanabe, Tetsuya Ito, Takashi Muraki, Hideaki Hamano, Shigeyuki Kawa
BACKGROUND: Immunoglobulin G4-related disease (IgG4-RD) is a newly recognized systemic condition characterized by high serum immunoglobulin G4 (IgG4) concentration and IgG4-bearing plasma cell infiltration in affected organs. Although it has become evident that IgG4-RD also involves the systemic aortic/arterial system, the precise details of this condition remain unclear. The present study sought to clarify the clinical features of IgG4-related periaortitis/periarteritis. METHODS: Among 223 patients with IgG4-RD, 179 (131 male, median onset age 67 years) were recruited for this study...
October 4, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28887257/a-rare-presentation-of-abdominal-aortic-aneurysm-renal-pelvis-rupture-due-to-compression
#4
Christopher Lowe, Khalid Bashaeb, George A Antoniou
Abdominal aortic aneurysms (AAAs) are usually asymptomatic. The compressive effects of internal iliac aneurysms are well described in the literature; however, we report what we believe to be the first case of rupture of the renal pelvis caused by compression by an infrarenal AAA. We describe the subsequent management and briefly review the literature.
September 6, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28887247/rare-presentation-of-a-syphilitic-aneurysm-of-the-infrarenal-aorta-with-contained-rupture
#5
Gautham Chitragari, Anne T Laux, Taylor D Hicks, Mark G Davies, Georges M Haidar
We report, to our knowledge, the first case of a rare syphilitic infrarenal aortouniiliac aneurysm with contained rupture that presented with midepigastric abdominal pain. Review of the patient's medical history revealed untreated syphilis and poorly treated congestive heart failure. Given his comorbidities, the patient was treated with an emergent endovascular aneurysm repair. His 30-day postoperative recovery period was uneventful, and follow-up imaging revealed complete resolution of the aneurysms. Syphilitic infrarenal aortic aneurysm is currently considered a rare entity in this era of antibiotics...
September 6, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28887239/atorvastatin-protects-kidney-from-remote-reperfusion-injury
#6
Carlos Henrique Marques Dos Santos, Doroty Mesquita Dourado, Baldomero Antonio Kato da Silva, Henrique Budib Dorsa Pontes, Euler de Azevedo Neto, Giovanna Serra da Cruz Vendas, Ian de Oliveira Chaves, João Victor Cunha Miranda, João Victor Durães Gomes Oliva, Letícia do Espirito Santo Dias, Murillo Henrique Martins de Almeida, Trícia Luna Sampaio
BACKGROUND: There is a need to find an effective treatment against reperfusion injury. The aim of the present study was to evaluate the capacity of the ischemic postconditioning and statin to prevent renal reperfusion injury. DESIGN AND SETTING: An experimental study developed at Universidade Anhanguera-Uniderp. METHODS: A total of 41 Wistar rats were distributed into 5 groups: ischemia and reperfusion (I/R), ischemic postconditioning (IPC), postconditioning + statin (IPC + S), statin (S), and sham...
September 6, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28870135/validation-of-an-assessment-tool-for-pre-operative-evar-planning
#7
Nikola Fatic, Pasha Normahani, Dejan Mars, Nigel J Standfield, Usman Jaffer
INTRODUCTION: Current methods of teaching endovascular aortic aneurysm repair (EVAR) planning involve non-criteria-based observations that lack validity. The primary aim of this study was to validate an EVAR Planning Objective Structured Assessment of Skill (EpOSAS) tool for the assessment of pre-operative EVAR planning skills. METHODS: Content analysis was performed in order to inform the formulation of EpOSAS domains. Thirty-five participants planned two cases of infra-renal abdominal aortic aneurysm for EVAR, using the OsiriX 7 platform...
September 1, 2017: Perfusion
https://www.readbyqxmd.com/read/28799317/absent-infra-renal-inferior-vena-cava-presenting-with-varicose-veins
#8
Mithun Kumar Kola, S Sandeep, Sri Harish Vankayalapati, M Srinivas Reddy
Inferior vena cava (IVC) anomalies were rare and usually asymptomatic. Among these, anomalies absence of infra-renal IVC is the rarest anomaly. Absence of infra-renal IVC may present with symptoms of venous insufficiency and idiopathic deep vein thrombosis. Contrast enhanced CT and MRI abdomen play crucial role in diagnosing these anomalies. These patients can be managed conservatively or by venous bypass. Identification of these anomalies is important to avoid surgeries for varicose veins.
August 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28712962/fenestrated-endograft-as-a-new-perspective-for-the-treatment-of-infrarenal-abdominal-aortic-aneurysm-with-a-congenital-pelvic-kidney-a-case-report-and-review-of-literature
#9
Barun Majumder, Anisha H Perera, Neil Browning, Mark MacGregor, Alex Chapman
The coexistence of abdominal aortic aneurysm (AAA) and congenital pelvic kidney is infrequent. Various treatment modalities have been reported in literature for the treatment of the aforementioned condition. We report a complete endovascular modality for the treatment of this association, especially for high-risk patients. Only one such treatment has been reported before. Compared with this previously reported case, we would like to share our experience with additional prototype testing, before surgery, which provided us with more detailed information about the planning and deployment of the branched endograft...
July 14, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28689945/chimney-stent-graft-repair-for-concurrent-inferior-mesenteric-artery-aneurysm-and-infrarenal-abdominal-aortic-aneurysm-case%C3%A2-report
#10
Zhen Wei Choo, Zhiwen Joseph Lo, Chun Hai Tan, Sundeep Punamiya, Sriram Narayanan
PURPOSE: To report a rare case of concurrent inferior mesenteric artery (IMA) aneurysm and infrarenal abdominal aortic aneurysm (AAA) with a novel indication for the use of chimney stent-graft technique in this patient. CASE REPORT: An 82-year-old man with an asymptomatic 4.4-cm fusiform AAA and 3.6-cm IMA aneurysm, coupled with chronic occlusion of celiac artery and superior mesenteric artery at the ostia, underwent endovascular repair of both aneurysms. Preservation of the IMA and treatment of both aneurysms were achieved with IMA aneurysm stenting, aortic aneurysm stenting and IMA chimney stenting...
July 6, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28648650/planning-execution-and-follow-up-for-endovascular-aortic-aneurysm-repair-using-a-highly-restrictive-iodinated-contrast-protocol-in-patients-with-severe-renal-disease
#11
E Gallitto, G L Faggioli, M Gargiulo, A Freyrie, R Pini, C Mascoli, S Ancetti, V Vento, A Stella
BACKGROUND: The cumulative amount of iodinated-contrast-medium necessary for EVAR planning, operative procedure and subsequent follow-up is a threat for the onset of end stage renal disease in patients with pre-operative impaired kidney function. Purpose of this study is to describe a mini-invasive approach aimed to minimize the exposure of these patients to iodinated-contrast-medium and the subsequent risk of renal function worsening. METHODS: From 2012 to 2015, all patients with abdominal aortic aneurysm (AAA) at high-surgical risk and fit for standard endovascular repair (simple aortic-iliac anatomy: proximal and distal neck length ≥15mm, no severe angulation), underwent EVAR through the following "near-zero contrast" approach, if their glomerular filtration rate (GFR) was <30 mL/min: pre-operative planning was performed by non-contrast enhanced computed tomography (CT) and duplex-ultrasound (DU); the origin of renal/hypogastric arteries and aortic bifurcation was evaluated and matched with vertebral bone landmarks and the endograft deployed accordingly, using < 20cc of isotonic iodinate-contrast-medium and contrast-enhancement-DU (CEUS)...
June 22, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28549955/a-peculiar-case-of-type-1-endoleak-after-nellix-endovascular-aneurysm-sac-sealing-clinical-presentation-and-management
#12
Ombretta Martinelli, Luigi Irace, Roberto Gattuso, Cristina Belli, Mauro Fresilli, Bruno Gossetti
We report a case of type 1 endoleak with an outflow via a lumbar artery (LA) following Nellix endovascular aneurysm sealing (EVAS) to discuss the specific peculiarities and management of this complication. A 64-year-old man (acetylsalicylic acid 3) underwent Nellix EVAS for an asymptomatic infrarenal aortic aneurysm. The 6-month duplex scanning ultrasound and magnetic resonance imaging showed a type IA endoleak with an outflow via an LA combined with a stable aneurysmal sac size. The subsequent 9-month imaging controls showed no changes of the endoleak cavity, but there was a slight enlargement in proximal neck size associated with the distal migration of both Nellix grafts...
May 24, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28533155/indications-and-techniques-for-robotic-pelvic-and-para-aortic-lymphadenectomy-with-sentinel-lymph-node-mapping-in-gynecologic-oncology
#13
REVIEW
Ketura Preya A Wisner, Sarfraz Ahmad, Robert W Holloway
Robotic-assisted laparoscopic surgery is the most common approach for the treatment of early-stage endometrial and cervical cancers in the US. Surgical staging requires pelvic and often aortic lymphadenectomy, depending on the primary tumor characteristics. Pelvic and aortic lymphadenectomy procedures may also be indicated for debulking of larger metastases to improve disease control. The infra-renal basin is an important anatomic site of metastasis from pelvic tumors, and robotic dissection techniques for this site have been described...
April 24, 2017: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28493108/percutaneous-septectomy-in-chronic-dissection-with-abdominal-aortic-aneurysm-creates-uniluminal-neck-for-evar
#14
Mark Colin Gissler, Yukihisa Ogawa, Jason T Lee, Venita Chandra, Michael D Dake
PURPOSE: The intent of this report is to describe the technical details and rationale of endovascular septectomy using a wire saw maneuver in cases of chronic aortic dissection and associated infra-renal aortic aneurysm to allow standard endovascular abdominal aortic graft placement; preliminary clinical experience is also retrospectively reviewed. MATERIALS AND METHODS: Between June 2013 and June 2016, four consecutive patients (mean age 55.3 years; range 52-58 years) with chronic type B aortic dissection and isolated infra-renal abdominal aortic aneurysm (AAA) underwent endovascular aneurysm repair (EVAR) following guidewire septectomy to create a suitable proximal aortic landing zone...
October 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28479445/atrium-advanta-v12-large-diameter-stent-graft-applications-for-infrarenal-abdominal-aortic-pseudoaneurysms-due%C3%A2-to%C3%A2-behcet-disease-safety-and-efficacy
#15
Çetin Murat Altay, Ayhan Alpar, Osman Melih Topcuoglu, Murat Bulent Kucukay, Dondu Uskudar Cansu, Tuncer Temel, Nilgun Isiksalan Ozbulbul, Fahrettin Kucukay
BACKGROUND: The aim of the study was to determine the safety and effectiveness of Atrium Advanta V12 large diameter stent-graft applications for infrarenal abdominal aortic pseudoaneurysms (due to Behcet disease [BD]). METHODS: Data of Advanta V12™ (Atrium Europe B.V, Mijdrecht, the Netherlands) applied 12 female patients (mean age 30.5 ± 6.3, range 26-44) with infrarenal abdominal aortic pseudoaneurysms were analyzed retrospectively. All Advanta V12 large diameter stent grafts were implemented from right or left sided 12F femoral sheaths...
October 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28457427/blood-flow-velocity-prediction-in-aorto-iliac-stent-grafts-using-computational-fluid-dynamics-and-taguchi-method
#16
Albert Y Chong, Barry J Doyle, Shirley Jansen, Stefan Ponosh, Julien Cisonni, Zhonghua Sun
Covered Endovascular Reconstruction of Aortic Bifurcation (CERAB) is a new technique to treat extensive aortoiliac occlusive disease with covered expandable stent grafts to rebuild the aortoiliac bifurcation. Post stenting Doppler ultrasound (DUS) measurement of maximum peak systolic velocity (PSVmax) in the stented segment is widely used to determine patency and for follow up surveillance due to the portability, affordability and ease of use. Anecdotally, changes in hemodynamics created by CERAB can lead to falsely high PSVmax requiring CT angiography (CTA) for further assessment...
May 1, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28452604/effects-of-dexmedetomidine-on-renal-tissue-after-lower-limb-ischemia-reperfusion-injury-in-streptozotocin-induced-diabetic-rats
#17
Meral Erdal Erbatur, Şaban Cem Sezen, Aslıhan Cavunt Bayraktar, Mustafa Arslan, Mustafa Kavutçu, Muhammed Enes Aydın
AIM: The aim of this study was to investigate whether dexmedetomidine - administered before ischemia - has protective effects against lower extremity ischemia reperfusion injury that induced by clamping and subsequent declamping of infra-renal abdominal aorta in streptozotocin-induced diabetic rats. MATERIAL AND METHODS: After obtaining ethical committee approval, four study groups each containing six rats were created (Control (Group C), diabetes-control (Group DM-C), diabetes I/R (Group DM-I/R), and diabetes-I/R-dexmedetomidine (Group DM-I/R-D)...
December 2017: Libyan Journal of Medicine
https://www.readbyqxmd.com/read/28436300/ten-year-single-centre-experience-with-type-ii-endoleaks-intervention-versus-observation
#18
COMPARATIVE STUDY
Ikram-Ul Haq, Arun Kelay, Meryl Davis, Jocelyn Brookes, Tara M Mastracci, Jason Constantinou
Our objective was to determine the relative merits of intervention or observation of type II endoleaks (T2Ls). A retrospective analysis was performed on 386 infra-renal endovascular aneurysm repair (IR-EVAR) patients from 2006 to 2015. Annual surveillance imaging of patients undergoing EVAR at our centre were analysed, and all endoleaks were subjected to a multidisciplinary team meeting for consideration and treatment. In the 10-year time frame, 386 patients (79.5±8.7 years) underwent an IR-EVAR. Eighty-one patients (21...
August 2017: Vascular Medicine
https://www.readbyqxmd.com/read/28414674/a-clot-possibly-due-to-loss-of-tnf-%C3%AE-supression
#19
J Broussard, M Berlinger, D Lauret
INTRODUCTION: Inflammation and venous thrombosis enjoy a close Relationship. We present a patient who had multiple DVTs following the discontinuation of anti- TNF-α therapy. CASE: A 34 year old African American female with a history of multiple DVT's, miscarriages, and reported Crohn's disease presented with shortness of breath. In the Emergency Department, CTA showed bilateral pulmonary emboli. The patient had been off adalimumab for one year and reported abdominal pain with 6-7 non-bloody bowel movements daily...
March 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/28390917/thoracic-endovascular-aortic-repair-into-the-false-lumen-in-chronic-aortic-dissection
#20
Arnoud V Kamman, David M Williams, Himanshu J Patel
BACKGROUND: Deployment of a stent graft for the treatment of aortic dissections is normally performed in the true lumen. However, in some rare occasions landing in the false lumen may be appropriate. METHODS: We present 2 different cases of chronic aortic dissection, where we opted to land the stent graft into the false lumen to treat the associated aneurysm. RESULTS: For the first case, the goal of thoracic endovascular aortic repair (TEVAR) was to exclude the aneurysm from within the false lumen because of a slit-like true lumen...
April 6, 2017: Annals of Vascular Surgery
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