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https://www.readbyqxmd.com/read/29690799/prediction-of-persistent-post-concussion-symptoms-following-mild-traumatic-brain-injury
#1
Maryse C Cnossen, Joukje van der Naalt, Jacoba M Spikman, Daan Nieboer, John K Yue, Ethan A Winkler, Geoffrey Manley, Nicole von Steinbuechel, Suzanne Polinder, Ewout W Steyerberg, Hester Lingsma
Persistent post-concussion symptoms (PPCS) occur frequently after mild traumatic brain injury (mTBI). The identification of patients at risk for poor outcome remains challenging since valid prediction models are missing. The objectives of the current study were to assess the quality and clinical value of prediction models for PPCS , and to develop a new model based on the synthesis of existing models and addition of complaints at emergency department (ED). MTBI patients (Glasgow Coma Scale score 13-15) were prospectively recruited from three Dutch level I trauma centers between 2013-2015 in the UPFRONT study...
April 25, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29682033/diagnostic-and-prognostic-capability-of-newer-magnetic-resonance-imaging-brain-sequences-in-diffuse-axonal-injury-patient
#2
Mayank Bansal, Virendra Deo Sinha, Juhi Bansal
Objectives: Diffuse axonal injury is one of the major causes of unconsciousness, profound neurologic deficits and persistent vegetative state after head trauma. In recent years, MR imaging has been gaining popularity as an adjunctive imaging method in patients with DAI. Our study aims to assess the relative diagnostic and prognostic capability of various MRI sequences. Patients and Methods: Retrospective observational study done in 1 year duration on 30 DAI patients...
April 2018: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29665763/neuroimaging-radiological-interpretation-system-niris-for-acute-traumatic-brain-injury-tbi
#3
Max Wintermark, Ying Li, Victoria Y Ding, Yingding Xu, Bin Jiang, Robyn L Ball, Michael Zeineh, Alisa Gean, Pina Sanelli
To develop an outcome-based NeuroImaging Radiological Interpretation System (NIRIS) for acute traumatic brain injury (TBI) patients that would standardize the interpretation of non-contrast head CTs and consolidate imaging findings into ordinal severity categories that would inform specific patient management actions and that could be used as a clinical decision support tool. We retrospectively identified all patients transported to our emergency department by ambulance or helicopter, for whom a trauma alert was triggered per established criteria and who underwent a non-contrast head CT due to suspicion of TBI, between November 2015 and April 2016...
April 18, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29652735/nursing-sensitive-outcomes-after-severe-traumatic-brain-injury-a-nationwide-study
#4
Lene Odgaard, Lena Aadal, Marianne Eskildsen, Ingrid Poulsen
BACKGROUND: Complications such as infections and conditions after immobilization are frequent after severe traumatic brain injury (TBI) due to compromised bodily functions. Traditionally, bodily functions are core elements in nursing, and therefore nurses in the rehabilitation departments are pivotal in the prevention of complications. Hence, the frequency of complications is an indicator of nursing care quality, which can be included in nursing-sensitive outcome indicators. To do so, it is necessary to know the frequency of the selected complications...
April 12, 2018: Journal of Neuroscience Nursing: Journal of the American Association of Neuroscience Nurses
https://www.readbyqxmd.com/read/29651746/human-neural-stem-progenitor-cells-derived-from-epileptic-human-brain-in-a-self-assembling-peptide-nanoscaffold-improve-traumatic-brain-injury-in-rats
#5
Ali Jahanbazi Jahan-Abad, Sajad Sahab Negah, Hassan Hosseini Ravandi, Sedigheh Ghasemi, Maryam Borhani-Haghighi, Walter Stummer, Ali Gorji, Maryam Khaleghi Ghadiri
Traumatic brain injury (TBI) is a disruption in the brain functions following a head trauma. Cell therapy may provide a promising treatment for TBI. Among different cell types, human neural stem cells cultured in self-assembling peptide scaffolds have been suggested as a potential novel method for cell replacement treatment after TBI. In the present study, we accessed the effects of human neural stem/progenitor cells (hNS/PCs) derived from epileptic human brain and human adipose-derived stromal/stem cells (hADSCs) seeded in PuraMatrix hydrogel (PM) on brain function after TBI in an animal model of brain injury...
April 12, 2018: Molecular Neurobiology
https://www.readbyqxmd.com/read/29625848/seizure-severity-is-correlated-with-severity-of-hypoxic-ischemic-injury-in-abusive-head-trauma
#6
Andra L Dingman, Nicholas V Stence, Brent R O'Neill, Stefan H Sillau, Kevin E Chapman
BACKGROUND: The objective of this study was to characterize hypoxic-ischemic injury and seizures in abusive head trauma. METHODS: We performed a retrospective study of 58 children with moderate or severe traumatic brain injury due to abusive head trauma. Continuous electroencephalograms and magnetic resonance images were scored. RESULTS: Electrographic seizures (51.2%) and hypoxic-ischemic injury (77.4%) were common in our cohort. Younger age was associated with electrographic seizures (no seizures: median age 13...
December 12, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/29622594/clinical-prediction-rules-for-abusive-head-trauma-a-systematic-review
#7
Helena Pfeiffer, Louise Crowe, Alison Mary Kemp, Laura Elizabeth Cowley, Anne S Smith, Franz E Babl
OBJECTIVE: Misdiagnosis of abusive head trauma (AHT) has serious consequences for children and families. This systematic review identifies and compares clinical prediction rules (CPredRs) assisting clinicians in assessing suspected AHT. DESIGN: We searched MEDLINE, Embase, PubMed and Cochrane databases (January 1996 to August 2016). Externally validated CPredRs focusing on the detection of AHT in the clinical setting were included. RESULTS: Of 110 potential articles identified, three studies met the inclusion criteria: the Pediatric Brain Injury Research Network (PediBIRN) 4-Variable AHT CPredR, the Predicting Abusive Head Trauma (PredAHT) tool and the Pittsburgh Infant Brain Injury Score (PIBIS)...
April 5, 2018: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29622334/pediatric-major-head-injury-not-a-minor-problem
#8
REVIEW
Aaron N Leetch, Bryan Wilson
Traumatic brain injury is a highly prevalent and devastating cause of morbidity and mortality in children. A rapid, stepwise approach to the traumatized child should proceed, addressing life-threatening problems first. Management focuses on preventing secondary injury from physiologic extremes such as hypoxemia, hypotension, prolonged hyperventilation, temperature extremes, and rapid changes in cerebral blood flow. Initial Glasgow Coma Score, hyperglycemia, and imaging are often prognostic of outcome. Surgically amenable lesions should be evacuated promptly...
May 2018: Emergency Medicine Clinics of North America
https://www.readbyqxmd.com/read/29620422/the-increase-in-copeptin-levels-in-mild-head-trauma-does-not-predict-the-severity-and-the-outcome-of-brain-damage
#9
Luigi M Casello, Livia Salmi, Isabella Zanotti, Clara A Gardino, Marco Baldrighi, Fabio Settanni, Gian C Avanzi
AIM: To investigate the copeptin prognostic role in mild head trauma. METHODS: We enrolled 105 adult patients who entered the emergency room because of recent mild head trauma; we evaluated: clinical picture, imaging and laboratory data (including copeptin). RESULTS: Copeptin resulted higher in mild head trauma patients compared with controls: 29.89 pmol/l versus 7.05 pmol/l; (p = 0.0008). Copeptin failed in identifying patients with or without brain lesions detected by CT scan, and patients with or without adverse events during the 30 days follow-up...
April 5, 2018: Biomarkers in Medicine
https://www.readbyqxmd.com/read/29614364/moderate-traumatic-brain-injury-clinical-characteristics-and-a-prognostic-model-of-12-month-outcome
#10
Cathrine Elisabeth Einarsen, Joukje van der Naalt, Bram Jacobs, Turid Follestad, Kent Gøran Moen, Anne Vik, Asta Kristine Haberg, Toril Skandsen
BACKGROUND: Patients with moderate traumatic brain injury (TBI) are often studied together with patients with severe TBI, even though expected outcome is better. Therefore, we aimed to describe patient characteristics and 12-month outcome, and to develop a prognostic model based on admission data, specifically for patients with moderate TBI. METHODS: Patients with Glasgow Coma Scale score of 9-13 and age ≥16 years were prospectively enrolled in two level I trauma centers in Europe...
March 31, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29608038/physical-therapy-needs-for-patients-with-physical-function-injuries-post-earthquake-disasters-a-systematic-review-of-chinese-and-western-literature
#11
Hao Li, John Nyland, Katrina Kuban, Justin Givens
BACKGROUND AND PURPOSE: Over the last 500 years, the most earthquakes with 10,000 or more fatalities and the most overall fatalities have occurred in China. Physical therapists must develop a better understanding of the patient and injury types that they are likely to treat post-earthquake disasters. This systematic review of Chinese and Western literature identified the primary patients treated by physical therapists post-earthquake disasters for injuries that negatively impacted physical function, activity, and participation...
April 2, 2018: Physiotherapy Research International: the Journal for Researchers and Clinicians in Physical Therapy
https://www.readbyqxmd.com/read/29606408/racial-and-ethnic-disparities-and-bias-in-the-evaluation-and-reporting-of-abusive-head-trauma
#12
Kent P Hymel, Antoinette L Laskey, Kathryn R Crowell, Ming Wang, Veronica Armijo-Garcia, Terra N Frazier, Kelly S Tieves, Robin Foster, Kerri Weeks
OBJECTIVE: To characterize racial and ethnic disparities in the evaluation and reporting of suspected abusive head trauma (AHT) across the 18 participating sites of the Pediatric Brain Injury Research Network (PediBIRN). We hypothesized that such disparities would be confirmed at multiple sites and occur more frequently in patients with a lower risk for AHT. STUDY DESIGN: Aggregate and site-specific analysis of the cross-sectional PediBIRN dataset, comparing AHT evaluation and reporting frequencies in subpopulations of white/non-Hispanic and minority race/ethnicity patients with lower vs higher risk for AHT...
March 29, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29602488/femoral-arterial-and-central-venous-catheters-in-the-trauma-resuscitation-room
#13
S R Hamada, M Fromentin, M Ronot, T Gauss, A Harrois, J Duranteau, C Paugam-Burtz
BACKGROUND: Arterial and central venous femoral catheters (fAC-CVC) use during the initial management of severe trauma patients is not a standard technique in most trauma centers. Arguments in favor of their use are: continuous monitoring of blood pressure, safe drug administration, easy blood sampling and potentially large bore venous access. The lack of evidence makes the practice heterogeneous. The aim of the present study was to describe the use and complications of fAC-CVC in the trauma bay in two centers where they are routinely used...
March 23, 2018: Injury
https://www.readbyqxmd.com/read/29599113/vomiting-with-head-trauma-and-risk-of-traumatic-brain-injury
#14
Meredith L Borland, Stuart R Dalziel, Natalie Phillips, Sarah Dalton, Mark D Lyttle, Silvia Bressan, Ed Oakley, Stephen J C Hearps, Amit Kochar, Jeremy Furyk, John A Cheek, Jocelyn Neutze, Franz E Babl
OBJECTIVES: To determine the prevalence of traumatic brain injuries in children who vomit after head injury and identify variables from published clinical decision rules (CDRs) that predict increased risk. METHODS: Secondary analysis of the Australasian Paediatric Head Injury Rule Study. Vomiting characteristics were assessed and correlated with CDR predictors and the presence of clinically important traumatic brain injury (ciTBI) or traumatic brain injury on computed tomography (TBI-CT)...
March 29, 2018: Pediatrics
https://www.readbyqxmd.com/read/29580346/head-ct-before-transfer-does-not-decrease-time-to-craniotomy-for-tbi-patients
#15
Peter M Tonui, Sarah K Spilman, Carlos A Pelaez, Mark R Mankins, Richard A Sidwell
Rural trauma education emphasizes that radiologic imaging should be discouraged if it delays transfer to definitive care. With increased capacity for image sharing, however, radiography obtained at referring hospitals (RH) could help providers at trauma centers (TC) prepare for patients with traumatic brain injury. We evaluated whether a head CT prior to transfer accelerated time to neurosurgical intervention at the TC. The study was conducted at a combined adult Level I and pediatric Level II TC with a catchment area that includes rural hospitals within a 150 mile radius...
February 1, 2018: American Surgeon
https://www.readbyqxmd.com/read/29573111/a-tale-of-two-cities-prehospital-intubation-with-or-without-paralysing-agents-for-traumatic-brain-injury
#16
Cino Bendinelli, Dominic Ku, Shane Nebauer, Kate L King, Teresa Howard, Russel Gruen, Tiffany Evans, Mark Fitzgerald, Zsolt J Balogh
BACKGROUND: The role of prehospital endotracheal intubation (PETI) for traumatic brain injury is unclear. In Victoria, paramedics use rapid sequence induction (RSI) drugs to facilitate PETI, while in New South Wales (NSW) they do not have access to paralysing agents. We hypothesized that RSI would both increase PETI rates and improve mortality. METHODS: Retrospective comparison of adult primary admissions (Glasgow Coma Scale <9 and abbreviated injury scale head and neck >2) to either Victorian or NSW trauma centre, which were compared with univariate and logistic regression analysis to estimate odds ratio for mortality and intensive care unit (ICU) length of stay...
March 23, 2018: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29572366/importance-of-source-images-of-time-of-flight-magnetic-resonance-angiography-in-the-diagnosis-of-low-flow-dural-arteriovenous-fistulae-after-traumatic-brain-injury
#17
Jun Tanaka, Atsushi Fujita, Taiji Ishii, Eiji Kohmura
Three-dimensional time-of-flight (TOF) magnetic resonance angiography (MRA) can reliably detect dural arteriovenous fistula (dAVF); however, TOF source images should be checked in cases with low-flow dAVFs. A 69-year-old woman reported intractable pulsatile tinnitus after head trauma. It was difficult to diagnose dAVF using conventional MRA, but it was confirmed using a TOF source image. Cerebral angiography revealed a dAVF with a small shunted pouch draining into the sigmoid sinus, accompanying the arterial jet flow...
March 22, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29561720/conscious-status-is-associated-with-the-likelihood-of-trauma-centre-care-and-mortality-in-patients-with-moderate-to-severe-traumatic-brain-injury
#18
Hatim A AlSulaim, R Sterling Haring, Anthony O Asemota, Blair J Smart, Joseph K Canner, Aslam Ejaz, David T Efron, Catherine G Velopulos, Elliott R Haut, Eric B Schneider
OBJECTIVE: To assess the relationship between The International Classification of Diseases, Ninth Revision, Clinical Modification-derived conscious status and mortality rates in trauma centres (TC) vs. non-trauma centres (NTC). METHODS: Patients in the 2006-2011 Nationwide Emergency Department Sample meeting, The Centers for Disease Control and Prevention criteria for traumatic brain injury (TBI), with head/neck Abbreviated Injury Scale (AIS) scores ≥3 were included...
March 21, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29558248/patterns-of-migraine-disease-in-otolaryngology-a-cheer-network-study
#19
Kristine A Schulz, Elnaz Esmati, Frederick A Godley, Claude L Hill, Ashkan Monfared, Michael Teixido, Debara L Tucci, David L Witsell
Objective To evaluate the prevalence of migraine disease in an otolaryngologic cohort and migraine-related otologic and sinonasal symptoms in this population. Study Design Cross-sectional study utilizing the CHEER (Creating Healthcare Excellence through Education and Research) network for recruitment. Setting Patients were recruited in a cross-sectional and pragmatic manner in 14 CHEER sites between June 2015 and March 2017 (9 academic, 5 community based). Subjects and Methods Patients were included if they were aged ≥18 years and seen for any concern that was not head and neck cancer...
March 1, 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29555324/plasma-d-dimer-safely-reduces-unnecessary-ct-scans-obtained-in-the-evaluation-of-pediatric-head-trauma
#20
Simone Langness, Erin Ward, Jonathan Halbach, Radhames Lizardo, Katherine Davenport, Stephen Bickler, Karen Kling, Hari Thangarajah, Julia Grabowski, Timothy Fairbanks
PURPOSE: Serum D-dimer has been proposed as a biomarker to aid in the diagnosis of pediatric traumatic brain injury (TBI). We investigated the accuracy of D-dimer in predicting the absence of TBI and evaluated the degree by which D-dimer could limit unnecessary computed tomography scans of the head (CTH). METHODS: Retrospective review of patients with suspected TBI from 2011 to 2013 who underwent evaluation with CTH and quantitative D-dimer. D-dimer levels were compared among patients with clinically-important TBI (ciTBI), TBI, isolated skull fracture and no injury...
April 2018: Journal of Pediatric Surgery
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