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https://www.readbyqxmd.com/read/28538610/diagnosis-treatment-and-surgical-repair-in-a-case-of-isolated-conjunctival-lichen-planus-causing-cicatricial-entropion
#1
Elizabeth A Cretara, Robert T Swan, Robert H Hill
A 50-year-old male presented with bilateral cicatricial entropion with subepithelial fibrosis and fornix foreshortening. Conjunctival biopsy showed lymphocytic infiltrate along the interface of the epithelium and lamina propria with linear, shaggy fibrinogen deposition along the epithelial basement membrane zone, supporting a diagnosis of lichen planus. The patient was treated with commercially available topical cyclosporine for 5 months after which bilateral lower eyelid splitting procedure with recession of the anterior lamella and complete excision of the lower eyelid lashes was performed...
May 22, 2017: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28484069/physician-perceptions-of-surveillance-follow-up-colonoscopy-in-older-adults
#2
Stephanie T Le, Brenna R Lash, Paul C Schroy, Audrey H Calderwood
BACKGROUND: Few data exist regarding when to stop surveillance colonoscopy among older adults with a history of adenomatous colorectal polyps. Our goal was to understand decision making around surveillance colonoscopy among primary care providers (PCPs) and gastroenterologists. METHODS: We designed a 15-item survey for PCPs and gastroenterologists that evaluated factors important in decision making about surveillance colonoscopy in older adults. RESULTS: In October 2015, 88 PCPs and 30 gastroenterologists completed the survey...
May 2017: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/28460838/editorial
#3
EDITORIAL
Gendie E Lash
No abstract text is available yet for this article.
April 27, 2017: Placenta
https://www.readbyqxmd.com/read/28456431/ifpa-meeting-2016-workshop-report-iii-decidua-trophoblast-interactions-trophoblast-implantation-and-invasion-immunology-at-the-maternal-fetal-interface-placental-inflammation
#4
John D Aplin, Alexander Beristain, Sonia DaSilva-Arnold, Caroline Dunk, Christina Duzyj, Thaddeus G Golos, Ulrike Kemmerling, Martin Knöfler, Murray D Mitchell, David M Olson, Margaret Petroff, Jürgen Pollheimer, Leticia Reyes, Pepper Schedin, Michael J Soares, Jennifer Stencel-Baerenwald, Kent L Thornburg, Gendie E Lash
Workshops are an important part of the IFPA annual meeting as they allow for discussion of specialised topics. At IFPA meeting 2016 there were twelve themed workshops, four of which are summarized in this report. These workshops related to various aspects of placental biology but collectively covered areas of decidual-trophoblast interaction, regulation of trophoblast invasion, immune cells at the maternal-fetal interface, and placental inflammation.
April 25, 2017: Placenta
https://www.readbyqxmd.com/read/28444108/racial-ethnic-differences-in-left-ventricular-structure-and-function-in-chronic-kidney-disease-the-chronic-renal-insufficiency-cohort
#5
Faraz S Ahmad, Xuan Cai, Katherine Kunkel, Ana C Ricardo, James P Lash, Dominic S Raj, Jiang He, Amanda H Anderson, Matthew J Budoff, Julie A Wright Nunes, Jason Roy, Jackson T Wright, Alan S Go, Martin G St John Sutton, John W Kusek, Tamara Isakova, Myles Wolf, Martin G Keane
BACKGROUND: Chronic kidney disease (CKD) is associated with increased risk of cardiovascular disease (CVD) and it is especially common among Blacks. Left ventricular hypertrophy (LVH) is an important subclinical marker of CVD, but there are limited data on racial variation in left ventricular structure and function among persons with CKD. METHODS: In a cross-sectional analysis of the Chronic Renal Insufficiency Cohort Study, we compared the prevalence of different types of left ventricular remodeling (concentric hypertrophy, eccentric hypertrophy, and concentric remodeling) by race/ethnicity...
April 24, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28438414/predictors-of-trachomatous-trichiasis-surgery-outcome
#6
Esmael Habtamu, Tariku Wondie, Sintayehu Aweke, Zerihun Tadesse, Mulat Zerihun, Bizuayehu Gashaw, Guadie S Wondimagegn, Hiwot D Mengistie, Saul N Rajak, Kelly Callahan, Helen A Weiss, Matthew J Burton
PURPOSE: Unfavorable outcomes after trachomatous trichiasis (TT) surgery are undermining the global trachoma elimination effort. This analysis investigates predictors of postoperative TT (PTT), eyelid contour abnormalities (ECAs), and granuloma in the 2 most common TT surgery procedures: posterior lamellar tarsal rotation (PLTR) and bilamellar tarsal rotation (BLTR). DESIGN: Secondary data analysis from a randomized, controlled, single-masked clinical trial. PARTICIPANTS: A total of 1000 patients with TT, with lashes touching the eye or evidence of epilation, in association with tarsal conjunctival scarring...
April 21, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28430833/on-the-need-for-quantitative-bias-analysis-in-the-peer-review-process
#7
Matthew P Fox, Timothy L Lash
Peer review is central to the process through which epidemiologists generate evidence to inform public health and medical interventions. Reviewers thereby act as critical gatekeepers to high-quality research. They are asked to carefully consider the validity of the proposed work or research findings by paying careful attention to the methodology and critiquing the importance of the insight gained. However, although many have noted problems with the peer-review system for both manuscripts and grant submissions, few solutions have been proposed to improve the process...
May 15, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28429466/psychosocial-outcomes-in-active-treatment-through-survivorship
#8
Sarah C Reed, Janice F Bell, Robin Whitney, Rebecca Lash, Katherine K Kim, Richard J Bold, Jill G Joseph
OBJECTIVE: To understand potential differences in psychosocial outcomes from active treatment to survivorship. METHODS: Using the Medical Expenditure Panel Survey Experiences with Cancer Survivorship Supplement (n = 1,360) we examined and compared psychosocial outcomes among respondents in active treatment with survivors by year(s) since treatment ended. Survey-weighted regression models were used to test associations between year(s) since treatment and depressive symptoms (PHQ-2), psychological distress (K-6) and cancer-specific worry related to recurrence...
April 20, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28415266/cavitation-and-spallation-in-liquid-metal-droplets-produced-by-subpicosecond-pulsed-laser-radiation
#9
M S Krivokorytov, A Yu Vinokhodov, Yu V Sidelnikov, V M Krivtsun, V O Kompanets, A A Lash, K N Koshelev, V V Medvedev
The deformation and fragmentation of liquid metal microdroplets by intense subpicosecond Ti:sapphire laser pulses is experimentally studied with stroboscopic shadow photography. The experiments are performed at a peak intensity of 10^{14}W/cm^{2} at the target's surface, which produces shock waves with pressures in the Mbar range. As a result of such a strong impact, the droplet is transformed into a complex-shaped hollow structure that undergoes asymmetrical expansion and eventually fragments. The hollow structure of the expanding target is explained by the effects of cavitation and spallation that follow the propagation of the laser-induced shock wave...
March 2017: Physical Review. E
https://www.readbyqxmd.com/read/28405740/mri-is-not-reliable-in-diagnosing-of-concomitant-anterolateral-ligament-and-anterior-cruciate-ligament-injuries-of-the-knee
#10
Brian M Devitt, Richard O'Sullivan, Julian A Feller, Nicholas Lash, Tabitha J Porter, Kate E Webster, Timothy S Whitehead
PURPOSE: There has been a renewed interest in the anterolateral structures of the knee, including description of the anterolateral ligament (ALL) as a distinct structure. Recognizing injury to the ALL is challenging, particularly given the subjective nature of physical examination. Consequently, focus has turned to magnetic resonance imaging (MRI) to reach a preoperative diagnosis of this region. The aim of this study was to examine the ability of 3-Tesla (3T) MRI to identify the ALL in ACL-injured patients compared to a matched control group of ACL-intact patients...
April 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28385100/predictive-factors-for-the-migration-of-endoscopic-self-expanding-metal-stents-placed-in-the-foregut
#11
Jordan L Singer, Amir H Aryaie, Mojtaba Fayezizadeh, Jon Lash, Jeffrey M Marks
BACKGROUND: With recent advancements in endoscopy, self-expandable metal stents (SEMS) have been used to treat gastrointestinal leaks, perforations, and strictures. Stent migration frequently complicates management and often requires additional treatments to reach resolution. Our study aimed to determine predictive factors for stent migration. METHODS: Consecutive procedures involving SEMS placed with and without fixation after upper gastrointestinal surgery between 2009 and 2014 were retrospectively reviewed...
April 1, 2017: Surgical Innovation
https://www.readbyqxmd.com/read/28375081/high-frequency-ultrasound-features-and-pathological-characteristics-of-medullary-thyroid-carcinoma
#12
Hua Wang, Mengmeng Liu, Jianqiu Yang, Yimin Song
To study high-frequency ultrasound features and pathological characteristics of medullary thyroid carcinoma (medullary thyroid carcinoma, MTC) with the purpose to improve the diagnostic accuracy of this disease. The clinical data of 20 cases of patients with MTC confirmed by the clinical surgery were retrospectively analyzed. And the high-frequency ultrasound features were analyzed and compared with the pathological characteristics. There were 16 cases with tumor invasion into one side of the thyroid gland; 17 cases with tumor in the middle-upper pole of the thyroid gland...
November 2016: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28372817/angiopoietin-2-in-placentation-and-tumor-biology-the-yin-and-yang-of-vascular-biology
#13
Qiong Wang, Gendie E Lash
There are several parallels between placental and tumor biology. Both require rapid acquisition of a blood supply to supply oxygen and nutrients, the placenta through neoangiogenesis and tumors by co-opting the existing vasculature. In addition, successful pregnancy also requires remodeling of the maternal uterine spiral arteries. Angiopoietins (Angs) are a family of angiogenic growth factors, the best studied being Ang-1 and Ang-2, which signal through the membrane tyrosine kinase receptor Tie2, and in simple terms have opposite effects with Ang-1 acting to stabilize newly formed blood vessels and Ang-2 having a destabilizing effect...
March 30, 2017: Placenta
https://www.readbyqxmd.com/read/28365226/rocky-mountain-spotted-fever-in-mexico-past-present-and-future
#14
REVIEW
Gerardo Álvarez-Hernández, Jesús Felipe González Roldán, Néstor Saúl Hernández Milan, R Ryan Lash, Casey Barton Behravesh, Christopher D Paddock
Rocky Mountain spotted fever, a tick-borne zoonosis caused by Rickettsia rickettsii, is among the most lethal of all infectious diseases in the Americas. In Mexico, the disease was first described during the early 1940s by scientists who carefully documented specific environmental determinants responsible for devastating outbreaks in several communities in the states of Sinaloa, Sonora, Durango, and Coahuila. These investigators also described the pivotal roles of domesticated dogs and Rhipicephalus sanguineus sensu lato (brown dog ticks) as drivers of epidemic levels of Rocky Mountain spotted fever...
March 29, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28343828/the-morscher-press-fit-acetabular-component-an-independent-long-term-review-at-18-22-years
#15
REVIEW
David P Gwynne-Jones, Heath W R Lash, Andrew W James, Ella E Iosua, John A Matheson
BACKGROUND: There are relatively few 20-year results of uncemented acetabular components, and most of these are modular designs. This study reports the 20-year results of a monoblock press-fit acetabular component. METHODS: A total of 122 total hip arthroplasties (111 patients) using the Morscher cup were reviewed at a mean of 19.7 years. The average age at implantation was 57.3 years (range, 36-74 years), and 81 (66%) were men. RESULTS: Twenty-two patients (25 hips) had died...
March 2, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28339306/descriptive-characteristics-of-colon-and-rectal-cancer-recurrence-in-a-danish-population-based-study
#16
Ashley C Holmes, Anders H Riis, Rune Erichsen, Veronika Fedirko, Eva Bjerre Ostenfeld, Mogens Vyberg, Ole Thorlacius-Ussing, Timothy L Lash
BACKGROUND: Recurrence is a common outcome among patients that have undergone an intended curative resection for colorectal cancer. However, data on factors that influence colorectal cancer recurrence are sparse. We report descriptive characteristics of both colon and rectal cancer recurrence in an unselected population. MATERIAL AND METHODS: We identified 21,152 patients with colorectal cancer diagnosed between May 2001 and December 2011 and registered with the Danish Colorectal Cancer Group...
March 24, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28338891/associations-of-statin-use-with-colorectal-cancer-recurrence-and-mortality-in-a-danish-cohort
#17
Timothy L Lash, Anders H Riis, Eva B Ostenfeld, Rune Erichsen, Mogens Vyberg, Thomas P Ahern, Ole Thorlacius-Ussing
In earlier studies of the influence of hydroxymethylglutaryl-coenzyme A reductase inhibitors (also known as statins) on colorectal cancer prognosis, investigators reported a reduced rate of cancer-specific mortality. Studies of recurrence are few and small. Using data from Danish registries, we followed 21,152 patients diagnosed with stage I-III colorectal cancer from 2001 to 2011. We estimated the association between statin use in the preceding year and cancer recurrence, cancer-specific mortality, and all-cause mortality rates...
March 1, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28301514/apolipoprotein-d-expression-does-not-predict-breast-cancer-recurrence-among-tamoxifen-treated-patients
#18
Daniella Klebaner, Stephen Hamilton-Dutoit, Thomas Ahern, Anatasha Crawford, Thomas Jakobsen, Deirdre P Cronin-Fenton, Per Damkier, Emiel Janssen, Anders Kjaersgaard, Anne Gulbech Ording, Håvard Søiland, Henrik Toft Sørensen, Timothy L Lash, Ylva Hellberg
BACKGROUND: Apolipoprotein D (ApoD) has been proposed as a predictor of breast cancer recurrence among estrogen receptor-positive (ER+), tamoxifen-treated patients. METHODS: We conducted a population-based case-control study nested in a population of 11,251 women aged 35-69 years at diagnosis with Stage I-III breast cancer between 1985 and 2001 on Denmark's Jutland Peninsula and registered with the Danish Breast Cancer Cooperative Group. We identified 541 recurrent or contralateral breast cancers cases among women with ER+ disease treated with tamoxifen for at least 1 year and 300 cases in women with ER- disease never treated with tamoxifen...
2017: PloS One
https://www.readbyqxmd.com/read/28292574/effect-of-lipid-based-dry-eye-supplements-on-the-tear-film-in-wearers-of-eye-cosmetics
#19
Michael T M Wang, Irene Sung Hee Cho, Soo Hee Jung, Jennifer P Craig
PURPOSE: To compare the effects on tear film parameters and contamination in cosmetic eyeliner wearers, after single application of two lipid-based dry eye treatments: a lipid-containing lubricant eye drop and a phospholipid liposomal spray. METHODS: Fifty participants were enrolled in a prospective, randomised, paired-eye, investigator-masked trial. Pencil eyeliner (Body Shop(®) Crayon Eye Definer) was applied to the upper eyelid periocular skin of both eyes, anterior to the lash line...
March 11, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/28228286/reproductive-immunology-time-to-look-forward
#20
EDITORIAL
Gendie Lash
No abstract text is available yet for this article.
February 2017: Journal of Reproductive Immunology
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