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https://www.readbyqxmd.com/read/28730914/the-health-economic-studies-of-hpv-vaccination-in-southeast-asian-countries-a-systematic-review
#1
Didik Setiawan, Monika Puri Oktora, Raymond Hutubessy, Arthorn Riewpaiboon, Maarten J Postma
The cervical cancer-related burden is an important problem in Southeast Asian (SEA) countries. However, only 3 out of 11 countries implement the comprehensive prevention program. Areas covered: This is a retrospective review from all relevant studies until 2015 from two main databases, MEDLINE/Pubmed and Embase in order to provide an evidence on the health economics of HPV vaccination in the region. Expert commentary: The implementation of HPV vaccination will generate substantial health and economic benefit in SEA countries since the number of cervical cancer cases in this region are generally high...
July 21, 2017: Expert Review of Vaccines
https://www.readbyqxmd.com/read/28727678/progress-toward-measles-elimination-bangladesh-2000-2016
#2
Sudhir Khanal, Rajendra Bohara, Stephen Chacko, Mohammad Sharifuzzaman, Mohammad Shamsuzzaman, James L Goodson, Alya Dabbagh, Katrina Kretsinger, Deepak Dhongde, Jayantha Liyanage, Sunil Bahl, Arun Thapa
In 2013, at the 66th session of the Regional Committee of the World Health Organization (WHO) South-East Asia Region (SEAR), a regional goal was established to eliminate measles and control rubella and congenital rubella syndrome* by 2020 (1). WHO-recommended measles elimination strategies in SEAR countries include 1) achieving and maintaining ≥95% coverage with 2 doses of measles-containing vaccine (MCV) in every district, delivered through the routine immunization program or through supplementary immunization activities (SIAs)(†); 2) developing and sustaining a sensitive and timely measles case-based surveillance system that meets targets for recommended performance indicators; and 3) developing and maintaining an accredited measles laboratory network (2)...
July 21, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28727007/best-management-practices-for-newly-weaned-calves-for-improved-health-and-well-being
#3
B K Wilson, C J Richards, D L Step, C R Krehbiel
Morbidity and mortality in newly weaned calves resulting from bovine respiratory disease (BRD) continue to be the most significant problems facing the beef industry. Morbidity attributed to BRD accounts for approximately 75% of total feedlot morbidity. Several experiments have documented the economic impacts of BRD. Direct costs attributable to BRD include death loss, treatment and labor costs, and prevention costs, while indirect costs associated with BRD include decreased growth performance and feed efficiency, increased days on feed, and decreased carcass merit and market value...
May 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28725322/recurrent-body-rash-warranted-second-desensitization-with-acyclovir-in-a-myeloma-patient-a-case-report
#4
Jack T Seki, Pamela Ng, Wallace Lam, Julie Cote, Anca Prica
A 75-year-old woman developed a moderately severe rash about a week and a half after the start of bortezomib (Btb)-based chemotherapy for IgG lambda multiple myeloma; at the time, she was also receiving acyclovir as antiviral prophylaxis in addition to herpes zoster (HZ) vaccination. HZ reactivation rate is high in Btb recipients; therefore, the timing of antiviral prevention is critical in relation to Btb. Attempts were made to identify the offending agent based on the timing of drugs administered and the appearance of skin lesions in relation to other drugs...
August 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28724343/vero-cell-technology-for-rapid-development-of-inactivated-whole-virus-vaccines-for-emerging-viral-diseases
#5
P Noel Barrett, Sara J Terpening, Doris Snow, Ronald R Cobb, Otfried Kistner
Rapid development and production of vaccines against emerging diseases requires well established, validated, robust technologies to allow industrial scale production and accelerated licensure of products. Areas covered: A versatile Vero cell platform has been developed and utilized to deliver a wide range of candidate and licensed vaccines against emerging viral diseases. This platform builds on the 35 years' experience and safety record with inactivated whole virus vaccines such as polio vaccine. The current platform has been optimized to include a novel double inactivation procedure in order to ensure a highly robust inactivation procedure for novel emerging viruses...
July 20, 2017: Expert Review of Vaccines
https://www.readbyqxmd.com/read/28724049/hepatitis-b-status-in-hemodialysis-patients
#6
Maia Nogueira Crown Guimarães, Tila Facincani, Sigrid De Sousa Dos Santos
BACKGROUND: Patients on chronic dialysis present a high prevalence of hepatitis B virus infection. Despite infection-control practices, surveillance of serological markers, and hepatitis B vaccination, there are still outbreaks of the disease in dialysis centers. OBJECTIVE: This study aims to assess the serologic and vaccination status for hepatitis B in hemodialysis patients. METHODS: This cross-sectional study assessed serologic markers and hepatitis B vaccination status of chronic kidney disease patients on regular dialysis program in São Carlos, SP, Brazil...
July 13, 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28723690/distribution-of-human-papillomavirus-genotypes-among-women-in-mashhad-iran
#7
Eskandar Taghizadeh, Forough Taheri, Hamed Abdolkarimi, Pedram Ghorbani Renani, Seyed Mohammad Gheibi Hayat
OBJECTIVE: Cervical cancer is the third most common malignancy in females. Since the human papillomavirus (HPV) genotype can vary geographically, it is essential to define its genotypic distribution before establishing health care policies and vaccination programs in any given area. The aim of this study was to determine the frequency of HPV types in women in Mashhad, Iran. METHODS: We used nested PCR and reverse dot-blot hybridization for genotyping. The study included 143 cervical cytology samples from Mashhad with confirmed papillomavirus infection by molecular methods...
July 20, 2017: Intervirology
https://www.readbyqxmd.com/read/28723489/immunotherapy-for-renal-cancer-sequencing-and-combinations
#8
REVIEW
Grant D Stewart, Maria De Santis, Bernard Escudier, Thomas Powles, Guru Sonpavde
CONTEXT: Current therapy for renal cell carcinoma (RCC) generally consists of the sequential administration of single agent therapy. Given the advent of T-cell checkpoint inhibitors, the role of combinations including these agents is being intensely interrogated. OBJECTIVE: To evaluate ongoing trials of combinations including immunotherapy and sequencing of agents to treat RCC. EVIDENCE ACQUISITION: Recent data and ongoing trials were analyzed to evaluate the direction of research in this arena...
December 15, 2016: European Urology Focus
https://www.readbyqxmd.com/read/28722601/rabies-in-myanmar-prevalent-preventable-but-not-prioritized
#9
Thet Thet Mu, Aye Aye Sein, Chit Soe, Nan Phyu Phyu Aung, Tint Tint Kyi, Josh Hanson
Despite the availability of proven measures to prevent the disease, rabies now kills more people in Myanmar than malaria. Although there are challenges in controlling rabies in such a large and culturally diverse country, Myanmar's successful National Malaria Control Program demonstrates what can be achieved with sufficient political, financial, and scientific commitment. Presently, however, Myanmar lacks a comparable program to coordinate the multifaceted approach that is necessary to control rabies. The national government has invested heavily in improving access to postexposure prophylaxis, but there should also be an emphasis on other, more cost-effective strategies, particularly mass canine vaccination, which has been an essential component of successful rabies elimination programs in other countries...
June 12, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28722581/epidemiology-of-diphtheria-in-india-1996-2016-implications-for-prevention-and-control
#10
Manoj Murhekar
Diphtheria is an acute disease caused by exotoxin-producing Corynebacterium diphtheriae. Globally, diphtheria has been showing a declining trend due to effective childhood vaccination programs. A substantial proportion of global burden of diphtheria is contributed by India. Hospital-based surveillance studies as well as diphtheria outbreaks published in last 20 years (1996-2016) indicate that diphtheria cases are frequent among school-going children and adolescents. In some Indian states, Muslim children are affected more...
June 26, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28720460/loss-of-chance-associated-with-sub-optimal-hpv-vaccination-coverage-rate-in-france
#11
Mathieu Uhart, Marjorie Adam, André Dahlab, Xavier Bresse
INTRODUCTION: Since 2007, HPV vaccination programs have been implemented in Europe. Significant real-life impact has already been reported in countries where the programs have been successfully implemented. In France, HPV vaccination coverage rate (VCR) is currently one of the lowest in Europe. This represents a missed opportunity for individuals who will not be protected. The study aimed to estimate the consequences of the sub-optimal VCR. METHODS: A dynamic transmission model was calibrated to the French setting...
June 2017: Papillomavirus Research
https://www.readbyqxmd.com/read/28720449/human-papillomavirus-in-anal-biopsy-tissues-and-liquid-based-cytology-samples-of-hiv-positive-and-hiv-negative-thai-men-who-have-sex-with-men
#12
Tippawan Pankam, Stephen J Kerr, Nipat Teeratakulpisan, Piyanee Rodbamrung, Rapeeporn Wongkanya, Somboon Keelawat, Komkrit Ruangritchankul, Piranun Hongchookiat, Ramida Watanapokasin, Nittaya Phanuphak
BACKGROUND: Men who have sex with men (MSM) are at high risk of developing human papillomavirus (HPV)-related anal cancer. We compared HPV genotypes in anal tissues (Bx) and anal liquid-based cytology fluid (LBC) from HIV-positive and HIV-negative MSM. METHODS: Bx (32 normal, 41 low-grade squamous intraepithelial lesions (LSIL) and 22 high-grade squamous intraepithelial lesions (HSIL)), along with LBC from the same visit, were selected from 61 HIV-positive and 34 HIV-negative MSM who enrolled into a prospective cohort in Bangkok, Thailand...
June 2017: Papillomavirus Research
https://www.readbyqxmd.com/read/28720442/impact-of-baseline-covariates-on-the-immunogenicity-of-the-9-valent-hpv-vaccine-a-combined-analysis-of-five-phase-iii-clinical-trials
#13
Lone K Petersen, Jaime Restrepo, Edson D Moreira, Ole-Erik Iversen, Punnee Pitisuttithum, Pierre Van Damme, Elmar A Joura, Sven-Erik Olsson, Daron Ferris, Stan Block, Anna R Giuliano, Xavier Bosch, Sophie Pils, Jack Cuzick, Suzanne M Garland, Warner Huh, Susanne K Kjaer, Oliver M Bautista, Donna Hyatt, Roger Maansson, Erin Moeller, Hong Qi, Christine Roberts, Alain Luxembourg
BACKGROUND: The immunogenicity profile of the 9-valent HPV (9vHPV) vaccine was evaluated across five phase III clinical studies conducted in girls and boys 9-15 years of age and young women 16-26 years of age. The effect of baseline characteristics of subjects on vaccine-induced HPV antibody responses was assessed. METHODS: Immunogenicity data from 11,304 subjects who received ≥1 dose of 9vHPV vaccine in five Phase III studies were analyzed. Vaccine was administered as a 3-dose regimen...
June 2017: Papillomavirus Research
https://www.readbyqxmd.com/read/28720082/cost-effectiveness-analysis-of-different-types-of-human-papillomavirus-vaccination-combined-with-a-cervical-cancer-screening-program-in-mainland-china
#14
Xiuting Mo, Ruoyan Gai Tobe, Lijie Wang, Xianchen Liu, Bin Wu, Huiwen Luo, Chie Nagata, Rintaro Mori, Takeo Nakayama
No abstract text is available yet for this article.
July 18, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28719253/cost-effectiveness-evaluation-of-a-novel-integrated-bite-case-management-program-for-the-control-of-human-rabies-haiti-2014-2015
#15
Eduardo A Undurraga, Martin I Meltzer, Cuc H Tran, Charisma Y Atkins, Melissa D Etheart, Max F Millien, Paul Adrien, Ryan M Wallace
AbstractHaiti has the highest burden of rabies in the Western hemisphere, with 130 estimated annual deaths. We present the cost-effectiveness evaluation of an integrated bite case management program combining community bite investigations and passive animal rabies surveillance, using a governmental perspective. The Haiti Animal Rabies Surveillance Program (HARSP) was first implemented in three communes of the West Department, Haiti. Our evaluation encompassed all individuals exposed to rabies in the study area (N = 2,289) in 2014-2015...
June 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28718247/public-private-partnership-and-utilization-of-maternal-and-child-health-services-in-district-abbottabad-pakistan
#16
Ayesha Imtiaz, Ghulam Farooq, Zia Ul Haq, Ashfaq Ahmed, Saeed Anwar
BACKGROUND: Public Private Partnership has been experimented as an approach in Pakistan in 2005 and in eighteen districts of Khyber Pakhtunkhwa including Abbottabad in 2011, to improve delivery of maternal and child health services. This study was conducted to assess the utilization of maternal and child health services before and after implementation of Public Private Partnership in district Abbottabad. METHODS: A cross sectional study was conducted in district Abbottabad from July to December 2014...
April 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28717338/perspectives-about-pandemic-influenza-and-its-prophylactic-measures-among-final-year-pharmacy-students-in-karachi-pakistan
#17
Najia Rahim, Wajiha Iffat, Sadia Shakeel, Muhammad Iyad Naeem, Faiza Qazi, Mehwish Rizvi, Iqbal Nasiri, Lubna Bashir, Faisal Muhammad Khan, Hina Yaseen, Shazia Jamshed
AIMS: In flu pandemics, pharmacy students' knowledge, attitudes, and practices are critical to save patients life. The objective of study was to determine the knowledge of and attitude toward the pandemic influenza among the pharmacy students of Karachi, Pakistan. SETTINGS AND DESIGNS: The cross-sectional study was conducted from September to December 2014 by adopting a prevalidated questionnaire distributed to senior pharmacy students (final year) in seven private and public sector universities of Karachi...
April 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28717311/using-real-time-polymerase-chain-reaction-as-an-alternative-rapid-method-for-enumeration-of-colony-count-in-live-brucella-vaccines
#18
Waleed S Shell, Mahmoud L Sayed, A A Samy, Ghada Mohamed Al-Sadek, Gina Mohamed Mohamed Abd El-Hamid, Abdel Hakam M Ali
AIM: Brucellosis is a major bacterial zoonosis of global importance affecting a range of animal species and man worldwide. It has economic, public health, and bio-risk importance. Control and prevention of animal brucellosis mainly depend on accurate diagnostic tools and implementation of effective and safe animal vaccination program. There are three types of animal Brucella live vaccines - Brucella melitensis Rev-1 vaccine, Brucella abortus S19, and B. abortus RB51. Evaluation of these vaccines depends mainly on enumeration of Brucella viable count...
June 2017: Veterinary World
https://www.readbyqxmd.com/read/28713023/an-extended-mathematical-model-of-tumor-growth-and-its-interaction-with-the-immune-system-to-be-used-for-developing-an-optimized-immunotherapy-treatment-protocol
#19
Milad Qomlaqi, Fariba Bahrami, Maryam Ajami, Jamshid Hajati
BACKGROUND: Chemotherapy is usually known as the main modality for cancer treatment. Nevertheless, most of chronic cancers could not be treated with chemotherapy alone. Immunotherapy is a new modality for cancer treatment that is effective for early stages of cancer and it has fewer side effects compared to chemotherapy, specifically for those types of cancer that are resistant to it. METHOD: This work presents an extended mathematical model to depict interactions between cancerous and adaptive immune system in mouse...
July 14, 2017: Mathematical Biosciences
https://www.readbyqxmd.com/read/28712191/assessing-the-role-of-education-in-adult-women-s-knowledge-and-awareness-of-human-papillomavirus-and-human-papillomavirus-vaccine
#20
Humera Ismail, Sarah Rafiq, Shafia Shakoor, Muhammad Tariq Karim, Rabia Raheel
BACKGROUND: Awareness and knowledge of Human Papillomavirus (HPV) and HPV vaccine among women are not satisfactory in developing countries. The aim of this study was to assess the role of education in adult women about knowledge and awareness of human papillomavirus (HPV) and HPV vaccine. METHODS: This cross-sectional study was carried out in women aged 19- 50 years attending the out-patient waiting area of a tertiary care hospital in Karachi from August 2014 to August 2015...
January 2017: Journal of Ayub Medical College, Abbottabad: JAMC
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