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gynaecology oncology

J McDonald, N Swami, B Hannon, C Lo, A Pope, A Oza, N Leighl, M Krzyzanowska, G Rodin, L W Le, C Zimmermann
BACKGROUND: Early palliative care improves the quality of life (QOL) and satisfaction with care of patients with advanced cancer, but little is known about its effect on caregivers. Here we report outcomes of caregiver satisfaction with care and QOL from a trial of early palliative care. PATIENT AND METHODS: Twenty-four medical oncology clinics were cluster-randomised, stratified by tumour site (lung, gastrointestinal, genitourinary, breast, gynaecological), to early palliative care team referral, or to standard oncology care with palliative care only as needed...
September 29, 2016: Annals of Oncology: Official Journal of the European Society for Medical Oncology
Lucy Dumas, Alistair Ring, John Butler, Tania Kalsi, Danielle Harari, Susana Banerjee
The incidence of most gynaecological malignancies rises significantly with increasing age. With an ageing population, the proportion of women over the age of 65 with cancer is expected to rise substantially over the next decade. Unfortunately, survival outcomes are much poorer in older patients and evidence suggests that older women with gynaecological cancers are less likely to receive current standard of care treatment options. Despite this, older women are under-represented in practice changing clinical studies...
August 29, 2016: Cancer Treatment Reviews
Thomas Vinotha, Thomas Anitha, Sebastian Ajit, Chandy Rachel, Peedicayil Abraham
INTRODUCTION: Patients referred with inadequately staged ovarian malignancies present a clinical dilemma. We report our experience with completion surgery in ovarian cancer. AIMS AND OBJECTIVES: To determine the benefits and risks of completion surgery in women with ovarian cancer who presented after having had inadequate primary surgery. METHODS: A retrospective case series of 30 women with ovarian cancer and one with fallopian tube cancer who had inadequate primary surgery underwent completion surgery at gynaecologic oncology unit in a tertiary level hospital in Tamil Nadu, India...
October 2016: Journal of Obstetrics and Gynaecology of India
Denis Querleu, François Planchamp, Luis Chiva, Christina Fotopoulou, Desmond Barton, David Cibula, Giovanni Aletti, Silvestro Carinelli, Carien Creutzberg, Ben Davidson, Philip Harter, Lene Lundvall, Christian Marth, Philippe Morice, Arash Rafii, Isabelle Ray-Coquard, Andrea Rockall, Cristiana Sessa, Ate van der Zee, Ignace Vergote, Andreas du Bois
OBJECTIVES: The surgical management of advanced ovarian cancer involves complex surgery. Implementation of a quality management program has a major impact on survival. The goal of this work was to develop a list of quality indicators (QIs) for advanced ovarian cancer surgery that can be used to audit and improve the clinical practice. This task has been carried out under the auspices of the European Society of Gynaecologic Oncology (ESGO). METHODS: Quality indicators were based on scientific evidence and/or expert consensus...
September 2016: International Journal of Gynecological Cancer
Giacomo Corrado, Giuseppe Cutillo, Giulia Pomati, Emanuela Mancini, Ermelinda Baiocco, Lodovico Patrizi, Maria Saltari, Francesco Barletta, Fabiola Patani, Enrico Vizza
BACKGROUND: The aim of this study was to assess the surgical and oncological outcome for the management of endometrial cancer (EC) by laparoendoscopic single-site surgery (LESS). PATIENTS AND METHODS: We performed a retrospective chart review of patients who underwent a LESS for EC. All the patients were treated by the same surgical team between July 2009 and June 2013 at the Gynaecologic Oncologic Unit, Regina Elena National Cancer Institute, Rome, Italy. RESULTS: A total of 50 women were included, with a median age of 45 years (range, 39-84 years) and a median body mass index (BMI) of 21...
October 2016: Journal of Minimal Access Surgery
Ming Yin Lin, Srinivas Kondalsamy-Chennakesavan, David Bernshaw, Pearly Khaw, Kailash Narayan
OBJECTIVE: The aim of this analysis was to examine the management of cervix cancer in elderly patients referred for radiotherapy and the results of treatment in terms of overall survival (OS), relapse-free survival (RFS), and treatment-related toxicities. METHODS: Patients were eligible if they were aged ≥75 years, newly diagnosed with cervix cancer and referred for radiotherapy as part of their treatment. Patient details were retrieved from the gynaecology service database where clinical, histopathological treatment and follow-up data were prospectively collected...
July 19, 2016: Journal of Gynecologic Oncology
Garri Tchartchian, Pamela Heldmann, Bernd Bojahr, Angelika Larbig, Rudy-Leon De Wilde
BACKGROUND AND AIMS: This controlled trial with II-1 evidence compared the safety and efficacy of the new laparoscopic-assisted combined hysterectomy (LACH) with the standard surgical technique laparoscopic-assisted vaginal hysterectomy (LAVH) in general and in patients displaying risk factors (large uterus, vaginal nulliparity, prior caesarean section). METHODS: From June 2007 to September 2008, 101 patients underwent a hysterectomy at the Clinic of Gynaecology, Obstetrics and Gynaecological Oncology at the Pius Hospital, University Hospital for Gynaecology in Oldenburg...
August 20, 2016: Gynecologic and Obstetric Investigation
Roberto Angioli, Francesco Plotti, Stella Capriglione, Giuseppe Scaletta, Nella Dugo, Alessia Aloisi, Claudia Lucia Piccolo, Riccardo Del Vescovo, Corrado Terranova, Bruno Beomonte Zobel
OBJECTIVE: The aim of this study is to prospectively evaluate and compare the accuracy of high-frequency TVS and of two type of MRI (dynamic contrast-enhanced MRI or diffusion-weighted MRI), in association with HE4 in preoperative endometrial cancer (EC) staging. STUDY DESIGN: Starting from January 2012 to February 2015, all patients with EC at prior endometrial biopsy, referred to the Division of Gynaecologic Oncology of the University Campus Bio-Medico of Rome, were prospectively included in the study...
August 17, 2016: Archives of Gynecology and Obstetrics
Hanoon P Pokharel, Neville F Hacker, Lesley Andrews
BACKGROUND: Genetic participation in gynaecological oncology multidisciplinary team meetings (MDT) may identify the sentinel cancer in women with hereditary breast-ovarian cancer syndrome or Lynch syndrome. AIMS: To identify the changing patterns of genetic referral from 2010 to 2014 and the outcomes of referrals through clinical MDT case review. MATERIALS AND METHODS: Medical records of cases of gynaecological cancer presented at the MDT meetings and genetics databases were reviewed to determine the frequency and outcomes of recommendations for genetic referral between 2010 and 2014...
August 17, 2016: Australian & New Zealand Journal of Obstetrics & Gynaecology
G Dadayal, M Weston, A Young, J L Graham, K Mehta, N Wilkinson, J A Spencer
AIM: To assess safety and accuracy of transvaginal ultrasound (TVUS)-guided biopsy in achieving a diagnosis of peritoneal carcinomatosis (PC). MATERIALS AND METHODS: This was a retrospective study comprising a cohort of 54 consecutive women aged 18-85 years referred from the gynaecological oncology multidisciplinary team meeting (MDTM) who attended for TVUS-guided biopsy procedures in a tertiary oncology centre over a 4-year period (2010-2014). Clinicopathological validation was assessed using online patient records and radiological information systems...
November 2016: Clinical Radiology
Anju Sahdev
CT of the abdomen and pelvis is the first line imaging modality for staging, selecting treatment options and assessing disease response in ovarian cancer. The staging CT provides disease distribution, disease burden and is the imaging surrogate for surgico-pathological FIGO staging. Optimal cyto-reductive surgery offers patients' the best chance for disease control or cure, but sub-optimal resection confers no advantage over chemotherapy and adversely increases the risk of post surgical complications. Although there is extensive literature comparing performance of CT against laparoscopy and surgery, for the staging abdominal and pelvic CT, there are currently no accepted guidelines for interpretation or routinely used minimum data set templates for reporting these complex CT scans often with extensive radiological findings...
2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
Carlos Sardinero-García, Andrés Santiago-Sáez, M Del Carmen Bravo, Bernardo Perea-Pérez, M Elena Albarrán-Juan, Elena Labajo-González, Julián Benito-León
OBJECTIVE: The loss of chance in healthcare has been forcibly introduced in the adjudications pronounced in recent years. Our objective was to analyse the verdicts of guilt resulting from the loss of chance ordered by the Contentious-Administrative Court (i.e., in the public healthcare system), in which both the origin of the disease to be treated and the sequelae were oncological processes. METHOD: We analysed 137 cancer-related court judgments from the Contentious-Administrative Court, which referred to the concept of loss of chance, issued in Spain up to May 2014...
July 26, 2016: Gaceta Sanitaria
Marloes Derks, Jacobus van der Velden, Minke M Frijstein, Willemijn M Vermeer, Anne M Stiggelbout, Jan Paul W R Roovers, Cornelis D de Kroon, Moniek M Ter Kuile, Gemma G Kenter
OBJECTIVE: This study aimed to compare urinary and bowel symptoms and quality of life (QoL) among women treated with a Wertheim-Meigs (WM, type III) or Wertheim-Okabayashi (WO, type IV) radical hysterectomy with pelvic lymphadenectomy for early-stage cervical cancer. METHODS: In this cross-sectional observational study, patients treated with a WO or a (nerve sparing) WM radical hysterectomy (with or without adjuvant radiotherapy) between January 2000 and December 2010 in the Center for Gynaecological Oncology Amsterdam or Leiden University Medical Center were included...
October 2016: International Journal of Gynecological Cancer
Paige E Tucker, Max K Bulsara, Stuart G Salfinger, Jason Jit-Sun Tan, Helena Green, Paul A Cohen
OBJECTIVE: To determine how frequently gynecologic oncologists discuss sexuality with women considering risk-reducing salpingo-oophorectomy. Secondary objectives were to assess the availability of resources, and the barriers to discussing sexuality. METHODS: Members of the Australian Society of Gynaecologic Oncologists, International Gynecologic Cancer Society, and Society of Gynecologic Oncology were invited to complete an online survey. Questions addressed frequency of, and barriers to, discussing sexuality, and availability of resources related to sexual issues...
September 2016: International Journal of Gynecological Cancer
Giacomo Corrado, Giuseppe Cutillo, Giulia Pomati, Emanuela Mancini, Ermelinda Baiocco, Lodovico Patrizi, Maria Saltari, Francesco Barletta, Fabiola Patani, Enrico Vizza
BACKGROUND: The aim of this study was to assess the surgical and oncological outcome for the management of endometrial cancer (EC) by laparoendoscopic single-site surgery (LESS). PATIENTS AND METHODS: We performed a retrospective chart review of patients who underwent a LESS for EC. All the patients were treated by the same surgical team between July 2009 and June 2013 at the Gynaecologic Oncologic Unit, Regina Elena National Cancer Institute, Rome, Italy. RESULTS: A total of 50 women were included, with a median age of 45 years (range, 39-84 years) and a median body mass index (BMI) of 21...
July 21, 2016: Journal of Minimal Access Surgery
Charlotte Ngô, Caroline Cornou, Léa Rossi, Anne-Sophie Bats, Chérazade Bensaid, Albane Frati, Claude Nos, Fabrice Lécuru
PURPOSE OF REVIEW: Robotically assisted laparoscopy has been introduced in the armamentarium of gynaecologic oncology surgeons. A lot of studies compared robotic surgery and laparotomy when the real issue is to demonstrate the interest and added value of robotically assisted laparoscopy versus standard laparoscopy. In this review, we will describe the most meaningful indications and advantages of robotically assisted laparoscopy in gynaecologic oncology. RECENT FINDINGS: The learning curve for advanced procedures in robot-assisted laparoscopy is shorter and easier than with the standard laparoscopy, especially for beginners...
September 2016: Current Opinion in Oncology
C Riola-Parada, L García-Cañamaque, V Pérez-Dueñas, M Garcerant-Tafur, J L Carreras-Delgado
OBJECTIVE: The aim of this review was to evaluate the diagnostic performance of simultaneous PET/MRI in oncology compared with that of PET/CT, based upon the available evidence. MATERIAL AND METHODS: A systematic search was performed in the Medline and Embase databases to identify original clinical articles published up to 21 January 2016, in order to compare simultaneous PET/MRI and PET/CT in oncology patients. RESULTS: A total of 57 articles were obtained that included various diseases: head and neck cancer (5), lung cancer and lung nodules (13), colorectal cancer (1), liver lesions (2), abdominal incidentalomas (1), neuroendocrine tumours (2), thyroid carcinoma (2), breast cancer (3), gynaecological cancer (2), prostate cancer (4), lymphoma (2), multiple myeloma (1), bone metastases (3), intracranial tumours (2), paediatric oncology (1) and various tumours (13)...
September 2016: Revista Española de Medicina Nuclear e Imagen Molecular
R M Alvarez, P Ramanathan
STUDY QUESTION: Does the type of cancer influence on the ovarian response to stimulation for fertility preservation (FP) in female oncology patients? SUMMARY ANSWER: Patients with gynaecological cancer have less number of retrieved mature oocytes compared with haematological and breast cancer patients. WHAT IS KNOWN ALREADY: Concerns about the impact of cancer therapy on future fertility have been raised and FP has become an important component in cancer management...
July 1, 2016: Human Reproduction
Natalie Percival, Angela George, Jennifer Gyertson, Monica Hamill, Andreia Fernandes, Emily Davies, Nazneen Rahman, Susana Banerjee
PURPOSE: The PARP inhibitor, Olaparib, is approved for women with BRCA-mutated ovarian cancer. Therefore there is an urgent need to test patients and obtain results in time to influence treatment. Models of BRCA testing, such as the mainstreaming oncogenetic pathway, involving oncology health professionals are being used. The authors report on the establishment of the extended role of the clinical nurse specialist in consenting women for BRCA testing in routine gynaecology-oncology clinics using the mainstreaming model...
June 23, 2016: British Journal of Nursing: BJN
Sergio Vásquez-Ciriaco, David Isla-Ortiz, Antonio Palomeque-Lopez, Jaime Aron García-Espinoza, Arturo Jarquín-Arremilla, Néstor Alonso Lechuga-García
BACKGROUND: The history of laparoscopic surgery in gynaecological diseases progressed with the advances of Semm, as well as with the development of tools, equipment, and energy that led to its development in all surgical areas, including oncology. OBJECTIVE: To present the initial experience in the laparoscopic treatment of benign and malignant gynaecological disease in the Hospital Regional de Alta Especialidad in Oaxaca. MATERIAL AND METHODS: An analysis was performed on a total of 44 cases, distributed into: type III radical hysterectomy for invasive cervical cancer, hysterectomy type I cervical cancer in situ, extrafascial hysterectomy for benign disease, routine endometrium, ovary and routine salpingo-oophorectomy...
June 16, 2016: Cirugia y Cirujanos
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