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https://www.readbyqxmd.com/read/28922886/intracranial-bypass-of-posterior-inferior-cerebellar-artery-aneurysms-indications-technical-aspects-and-clinical-outcomes
#1
David J Bonda, Mohamad Labib, Jeffrey M Katz, Rafael A Ortiz, David Chalif, Avi Setton, David J Langer, Amir R Dehdashti
BACKGROUND: For some posterior inferior cerebellar artery (PICA) aneurysms, there is no constructive endovascular or direct surgical clipping option. Intracranial bypass is an alternative to a deconstructive technique. OBJECTIVE: To evaluate the clinical features, surgical techniques, and outcome of PICA aneurysms treated with bypass and obliteration of the diseased segment. METHODS: Retrospective review of PICA aneurysms treated via intracranial bypass was performed...
October 1, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/28922882/microsurgical-anatomy-of-the-interfascial-vein-its-significance-in-the-interfascial-dissection-of-the-pterional-approach
#2
Alvaro Campero, Pablo Ajler, Martín Paíz, Ramiro López Elizalde
BACKGROUND: The pterional approach (PA), together with its variants, is still one of the most common methods used by surgeons to reach the anterior and middle cranial base. A highly important technical detail during a PA is the preservation of the frontotemporal branch of the facial nerve, which can be achieved through an interfascial dissection. OBJECTIVE: To describe the anatomy of the interfascial vein (IFV), highlighting its recognition as a significant anatomic reference to perform an interfascial dissection (IFD)...
October 1, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/28922880/a-side-door-to-meckel-s-cave-anatomic-feasibility-study-for-the-lateral-transorbital-approach
#3
Blake Harrison Priddy, Cristian Ferrareze Nunes, Andre Beer-Furlan, Ricardo Carrau, Iacopo Dallan, Daniel Monte-Serrat Prevedello
BACKGROUND: In the last decade, endoscopic skull base surgery has significantly developed and generated a plethora of techniques and approaches for access to the cranial ventral floor. However, the exploration for the least-aggressive, maximally efficient approach continues. OBJECTIVE: To describe in detail an anatomical study, along with the technical nuances of a novel endoscopic approach to Meckel's Cave (MC) using a lateral transorbital (LTO) route. METHODS: Eighteen orbits of injected cadaveric specimens were operated on, using an endoscopic LTO approach to MC, middle cranial fossa, and paramedian skull base preserving the orbital rim...
October 1, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/28922245/a-craniometric-analysis-of-cranial-base-and-cranial-vault-differences-in-patients-with-metopic-craniosynostosis
#4
Sanjay Naran, Daniel Mazzaferro, Ari Wes, Arastoo Vossough, Scott P Bartlett, Jesse A Taylor
PURPOSE: The effect of synostosis is not confined to the immediate vicinity of the suture. The authors hypothesized metopic craniosynostosis results in migration of lateral structures from midline, and differences in segmental volume of the cranial fossa. METHODS: A retrospective case-controlled cohort analysis of patients with nonsyndromic metopic craniosynostosis was performed. Craniometric angles, distances to landmarks from midline, cephalic index, and segmented volume ratios were calculated...
September 15, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28922233/endoscopic-versus-open-repair-for-craniosynostosis-in-infants-using-propensity-score-matching-to-compare-outcomes-a-multicenter-study-from-the-pediatric-craniofacial-collaborative-group
#5
Douglas R Thompson, David Zurakowski, Charles M Haberkern, Paul A Stricker, Petra M Meier
BACKGROUND: The North American Pediatric Craniofacial Collaborative Group (PCCG) established the Pediatric Craniofacial Surgery Perioperative Registry to evaluate outcomes in infants and children undergoing craniosynostosis repair. The goal of this multicenter study was to utilize this registry to assess differences in blood utilization, intensive care unit (ICU) utilization, duration of hospitalization, and perioperative complications between endoscopic-assisted (ESC) and open repair in infants with craniosynostosis...
September 14, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28921909/first-natural-endocranial-cast-of-a-fossil-snake-cretaceous-of-patagonia-argentina
#6
Laura N Triviño, Adriana M Albino, María T Dozo, Jorge D Williams
In this study, we describe a natural endocranial cast included in a partially preserved medium-sized skull of the Upper Cretaceous South American snake Dinilysia patagonica. The endocast is composed of sedimentary filling of the cranial cavity in which the posterior brain, the vessels, the cranial nerves, and the inner ear surrounded by delicate semicircular canals, are represented. It is simple in form, with little differentiation between the three main areas (Forebrain, Midbrain and Hindbrain), and without flexures...
September 16, 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/28921242/use-of-computer-assisted-design-and-manufacturing-to-localize-dural-venous-sinuses-during-reconstructive-surgery-for-craniosynostosis
#7
Rajiv R Iyer, Adela Wu, Alexandra Macmillan, Leila Musavi, Regina Cho, Joseph Lopez, George I Jallo, Amir H Dorafshar, Edward S Ahn
OBJECTIVE: Cranial vault remodeling surgery for craniosynostosis carries the potential risk of dural venous sinus injury given the extensive bony exposure. Identification of the dural venous sinuses can be challenging in patients with craniosynostosis given the lack of accurate surface-localizing landmarks. Computer-aided design and manufacturing (CAD/CAM) has allowed surgeons to pre-operatively plan these complex procedures in an effort to increase reconstructive efficiency. An added benefit of this technology is the ability to intraoperatively map the dural venous sinuses based on pre-operative imaging...
September 18, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28920820/morbidity-and-mortality-of-wild-turtles-at-a-north-carolina-wildlife-clinic-a-10-year-retrospective
#8
Alexandra Sack, Eric Butler, Peter Cowen, Gregory A Lewbart
The medical records from 1,847 wild turtle patients seen between 2005 and 2014 by the Turtle Rescue Team at the North Carolina State University College of Veterinary Medicine were analyzed. Eastern box turtles (Terrapene carolina carolina; n = 947), yellow-bellied sliders (Trachemys scripta scripta; n = 301), cooters ( Pseudemys spp.; n = 235), common snapping turtles (Chelydra serpentina; n = 165), and eastern painted turtles (Chrysemys picta; n = 93) made up 94.3% of all patients. Patient admissions peaked in May when 25...
September 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28919490/alcohol-exposure-induces-chick-craniofacial-bone-defects-by-negatively-affecting-cranial-neural-crest-development
#9
Ping Zhang, Guang Wang, Zhuangling Lin, Yushi Wu, Jing Zhang, Meng Liu, Kenneth Ka Ho Lee, Manli Chuai, Xuesong Yang
Excess alcohol consumption during pregnancy could lead to fetal alcohol syndrome (FAS). However, the molecular mechanism leading to craniofacial abnormality, a feature of FAS, is still poorly understood. The cranial neural crest cells (NCCs) contribute to the formation of the craniofacial bones. Therefore, NCCs exposed to ethanol was investigated - using chick embryos and in vitro explant culture as experimental models. We demonstrated that exposure to 2% ethanol induced craniofacial defects, which includes parietal defect, in the developing chick fetus...
September 14, 2017: Toxicology Letters
https://www.readbyqxmd.com/read/28919310/cadherin-11-promotes-neural-crest-cell-spreading-by-reducing-intracellular-tension-mapping-adhesion-and-mechanics-in-neural-crest-explants-by-atomic-force-microscopy
#10
REVIEW
Carina Blaue, Jubin Kashef, Clemens M Franz
During development cranial neural crest cells (NCCs) display a striking transition from collective to single-cell migration, but the mechanisms enabling individual NCCs to separate from the neural crest tissue are still incompletely understood. In this study we have employed atomic force microscopy (AFM) to investigate potential adhesive and mechanical changes associated with the dissociation of individual cells from cohesive Xenopus NCC explants at early stages of migration. AFM-based single-cell force spectroscopy (SCFS) revealed a uniform distribution of cell-cell adhesion forces within NCC explants, including semi-detached leader cells in the process of delaminating from the explant edge...
September 14, 2017: Seminars in Cell & Developmental Biology
https://www.readbyqxmd.com/read/28918284/new-insights-into-human-female-reproductive-tract-development
#11
Stanley J Robboy, Takeshi Kurita, Laurence Baskin, Gerald R Cunha
We present a detailed review of the embryonic and fetal development of the human female reproductive tract utilizing specimens from the 5th through the 22nd gestational week. Hematoxylin and eosin (H&E) as well as immunohistochemical stains were used to study the development of the human uterine tube, endometrium, myometrium, uterine cervix and vagina. Our study revisits and updates the classical reports of Koff (1933) and Bulmer (1957) and presents new data on development of human vaginal epithelium. Koff proposed that the upper 4/5ths of the vagina is derived from Müllerian epithelium and the lower 1/5th derived from urogenital sinus epithelium, while Bulmer proposed that vaginal epithelium derives solely from urogenital sinus epithelium...
August 11, 2017: Differentiation; Research in Biological Diversity
https://www.readbyqxmd.com/read/28917901/polysaccharides-based-injectable-hydrogel-compositing-bio-glass-for-cranial-bone-repair
#12
Xiao Bai, Shaoyu Lü, Haidi Liu, Zhen Cao, Piao Ning, Zengqiang Wang, Chunmei Gao, Boli Ni, Dongyang Ma, Mingzhu Liu
Bone disease is a public health problem around the word, and it is urgent to develop novel tissue engineering scaffolds for the complicated cranial bone regeneration. The present work developed a novel triple crosslinked polysaccharides based injectable hydrogel to composite bio-glass (BG) for cranial bone repair. Dynamic mechanical analysis showed the storage modulus (G') of the hydrogel reached to ∼4000Pa. While after compositing BG, G' exceeded 4500Pa. The degradation behavior of the hydrogel is influenced by hydrogel composition, crosslinking methods and degradation environment...
November 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28917287/intraoperative-computed-tomography-in-cranial-neurosurgery
#13
REVIEW
Christian Schichor, Nicole Terpolilli, Jun Thorsteinsdottir, Jörg-Christian Tonn
The challenge for treating complex lesions with the aim of minimal surgery-related morbidity has generated an increasing demand for sophisticated intraoperative imaging modalities. Newest generations of intraoperative computed tomography (CT) scanners offer a multitude of hardware and software improvements resulting in higher image quality that further propagates its everyday usage in the interdisciplinary operative setting. This article describes workflow and applicability of intraoperative CT scanning in cranial neurosurgery, in subspecialties like skull base or vascular neurosurgery, and its advantages and limitations...
October 2017: Neurosurgery Clinics of North America
https://www.readbyqxmd.com/read/28917275/historical-current-and-future-intraoperative-imaging-modalities
#14
REVIEW
Christopher Nimsky, Barbara Carl
Intraoperative imaging has become widely accepted in neurosurgery in recent years. The possibility to objectively determine the extent of tumor removal is highly advantageous. If the resection is incomplete, clinicians can attempt to remove the residual tumor that was missed during the same operation. Furthermore, the positioning of implants in spinal surgery, as well as in cranial surgery, can be controlled and modified during the procedure. Intraoperative imaging acts as immediate quality control and offers improved patient safety...
October 2017: Neurosurgery Clinics of North America
https://www.readbyqxmd.com/read/28917258/stereotactic-body-radiotherapy-for-early-stage-lung-cancer-historical-developments-and-future-strategies
#15
Kevin L M Chua, Iris Sin, Kam W Fong, Melvin L K Chua, Hiroshi Onishi
The application of radiosurgery dose escalation extra-cranially in a moving target, surrounded by critical normal tissue, presents unique dosimetric and clinical challenges. Building on a strong foundation of robust technological advancements and well-planned clinical studies, lung stereotactic body radiotherapy (SBRT) has firmly established its place in the management of early stage non-small cell lung cancer (NSCLC). Nevertheless, favourable outcomes and long-term survival still evade a substantial proportion of patients, especially for central and larger peripheral lung tumours...
September 2017: Chinese Clinical Oncology
https://www.readbyqxmd.com/read/28917250/emerging-technologies-in-stereotactic-body-radiotherapy
#16
Lijun Ma, Lei Wang, Chia-Lin Tseng, Arjun Sahgal
Stereotactic body radiation therapy (SBRT) stems from the initial developments of intra-cranial stereotactic radiosurgery (SRS). Despite similarity in their names and clinical goals of delivering a sufficiently high tumoricidal dose, maximal sparing of the surrounding normal tissues and a short treatment course, SBRT technologies have transformed from the early days of body frame-based treatments with X-ray verification to primarily image-guided procedures with cone-beam CT or stereoscopic X-ray systems and non-rigid body immo-bilization...
September 2017: Chinese Clinical Oncology
https://www.readbyqxmd.com/read/28916909/-idiopathic-cranial-nerve-failure
#17
P Urban
Cranial nerve lesions require a thorough diagnostic work-up and known etiologies have to be excluded before the term idiopathic can be considered. The focus of the present review is on idiopathic peripheral facial nerve paralysis (Bell's palsy) for which this terminology has been established. For all other cranial nerve lesions the typical clinical signs, established etiologies and possible diagnostic pitfalls are discussed.
September 15, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/28915338/neurocognitive-psychosocial-and-quality-of-life-outcomes-in-adult-survivors-of-childhood-non-hodgkin-lymphoma
#18
Matthew J Ehrhardt, Daniel A Mulrooney, Chenghong Li, Malek J Baassiri, Kari Bjornard, John T Sandlund, Tara M Brinkman, I-Chan Huang, Deo Kumar Srivastava, Kirsten K Ness, Leslie L Robison, Melissa M Hudson, Kevin R Krull
BACKGROUND: Children with non-Hodgkin lymphoma (NHL) undergo treatment with central nervous system-directed therapy, the potentially neurotoxic effects of which have not been reported in NHL survivors. METHODS: NHL survivors (n = 187) participating in the St. Jude Lifetime Cohort who were 10 or more years from their diagnosis and were 18 years old or older underwent neurocognitive, emotional distress (Brief Symptom Inventory 18), and health-related quality of life (HRQOL) assessments (36-Item Short Form Health Survey)...
September 15, 2017: Cancer
https://www.readbyqxmd.com/read/28914870/-shunt-induced-craniosynostosis-topicality-of-the-problem-choice-of-the-approach-and-features-of-surgical-treatment
#19
S A Kim, G V Letyagin, V E Danilin, A A Sysoeva
RATIONALE: Shunt-induced craniosynostosis is one of the late complications of CSF shunting surgery, which affects the patient's condition, clinical picture, and treatment approach. OBJECTIVE: to evaluate the prevalence rate and clinical significance of this disease, define the indications for surgery, and choose the optimal surgical approach. MATERIAL AND METHODS: The study included 59 children with shunt system dysfunction, aged 1 to 14 years, who were treated at the Department in the period from 2014 to 2016...
2017: Zhurnal Voprosy Neĭrokhirurgii Imeni N. N. Burdenko
https://www.readbyqxmd.com/read/28914866/-extended-endoscopic-endonasal-posterior-transclival-approach-to-tumors-of-the-clival-region-and-ventral-posterior-cranial-fossa-part-1-topographic-and-anatomical-features-of-the-clivus-and-adjacent-structures
#20
A N Shkarubo, K V Koval', G F Dobrovol'skiy, M A Shkarubo, V V Karnaukhov, B A Kadashev, D N Andreev, I V Chernov, O A Gadzhieva, O Yu Aleshkina, E A Anisimova, P L Kalinin, M A Kutin, D V Fomichev, O I Sharipov, D B Ismailov, E S Selivanov
OBJECTIVE: to describe the main topographic and anatomical features of the clival region and its adjacent structures for improvement and optimization of the extended endoscopic endonasal posterior (transclival) approach for resection of tumors of the clival region and ventral posterior cranial fossa. MATERIAL AND METHODS: We performed a craniometric study of 125 human skulls and a topographic anatomical study of heads of 25 cadavers, the arterial and venous bed of which was stained with colored silicone (the staining technique was developed by the authors) to visualize bed features and individual variability...
2017: Zhurnal Voprosy Neĭrokhirurgii Imeni N. N. Burdenko
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