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https://www.readbyqxmd.com/read/28433976/isolated-duodenal-rupture-primary-repair-without-diversion-is-it-safe-review-of-literature
#1
Muwaffaq Mezeil Telfah
Isolated duodenal rupture is a rare injury encountered among children following blunt abdominal trauma. Early diagnosis and treatment are essential to decrease the associated morbidity and mortality. The debate is about the optimum operative management. We report a 6-year-old child who presented with acute abdominal pain due to isolated duodenal injury following blunt abdominal trauma. Emergency laparotomy revealed duodenal rupture at the junction of the first and second part of duodenum and absence of any other visceral injuries...
April 22, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28432741/pharmacokinetic-and-pharmacodynamic-effects-of-two-omeprazole-formulations-on-stomach-ph-and-gastric-ulcer-scores
#2
S Raidal, F M Andrews, S G Nielsen, G Trope
REASONS FOR PERFORMING THE STUDY: Limited data are available on the relative pharmacokinetics and pharmacodynamics of different omeprazole formulations. OBJECTIVES: To compare pharmacokinetic and pharmacodynamic effects of a novel omeprazole formulation against a currently registered product. STUDY DESIGN: Masked two period, two treatment crossover. METHODS: Twelve clinically healthy horses were studied over two 6-day treatment periods...
April 22, 2017: Equine Veterinary Journal
https://www.readbyqxmd.com/read/28426477/incidence-of-adhesive-bowel-obstruction-after-colon-cancer-surgery-and-its-risk-factors-a-nationwide-claim-study
#3
Gi Hyeon Seo, Eun Kyung Choe, Kyu Joo Park, Young Jun Chai
OBJECTIVE: To elucidate the incidence of adhesive postoperative bowel obstruction (PBO) after colon cancer surgery and its risk factors using nationwide claim data. BACKGROUND: PBO has a significant impact on quality of life and medical costs after colectomy, though most of the literature consists of single-institution analyses. METHODS: Data from 24,645 patients who underwent regional colectomy for colon cancer from 2010 to 2012 and had at least 3 years of follow up were obtained from the Health Insurance Review and Assessment Service database...
April 19, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28424245/oral-nutrition-in-children-with-bronchiolitis-on-high-flow-nasal-cannula-is-well-tolerated
#4
Anthony Alexander Sochet, Jessica Ann McGee, Tessie Wazeerah October
OBJECTIVES: To determine the incidence of aspiration-related respiratory failure and nutrition interruptions in children with bronchiolitis on high-flow nasal cannula (HFNC) receiving enteral nutrition. METHODS: We performed a single-center, prospective, observational cohort study within a 313-bed tertiary medical center from January through December 2015. We included term children 1 month to 2 years of age without comorbid bacterial pneumonia or chronic medical conditions who were diagnosed with bronchiolitis while receiving HFNC and enteral nutrition...
April 19, 2017: Hospital Pediatrics
https://www.readbyqxmd.com/read/28416428/-nasogastric-rehydration-for-treating-children-with-gastroenteritis
#5
B Rébeillé-Borgella, C Barbier, R Moussaoui, A Faisant, A-P Michard-Lenoir, A Rubio
INTRODUCTION: When oral rehydration is not feasible, enteral rehydration via the nasogastric route has been the ESPGHAN recommended method of rehydration since 2008, rather than intravenous rehydration (IVR), for children with acute gastroenteritis. However, these recommendations are rarely followed in France. Since 2011, in case of failure of oral rehydration, enteral rehydration has been used as a first-line therapy in the Children's Emergency Department at the Grenoble-Alpes University Hospital...
April 14, 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/28416417/in-vitro-evaluation-of-nasogastric-ng-tube-delivery-performance-of-esomeprazole-magnesium-delayed-release-capsules
#6
Alicia Hoover, Dajun Sun, Hong Wen, Wenlei Jiang, Minglei Cui, Xiaojian Jiang, David Keire, Changning Guo
Enteral feeding tubes are used to deliver food or drugs to patients that cannot swallow. To deliver delayed-release drugs that are formulated as enteric coated granules to these patients via feeding tubes requires that they be suspended in water prior to administration. Importantly, the suspension of enteric granules in water of varying pH can cause damage to the enteric coating and affect the bioavailability of the drug. Here, analytical methods for testing acid resistance stability and particle size distribution (PSD) of esomeprazole granules were utilized to monitor the integrity of the granule enteric coating after water pretreatment and delivery through an oral syringe and nasogastric (NG) tube...
April 14, 2017: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28412028/-effectiveness-of-erlotinib-in-critical-care-unit-in-patients-with-non-small-cell-lung-cancer-with-egfr-mutation
#7
M Dewolf, C Dayen, C Garoute, W Khamis, M Fourrier, F Rousselle, M Sadki, F Le Meunier, R Suguenot, E Lecuyer, H Bentayeb, Y Douadi, P Berna
INTRODUCTION: The search for mutations epidermal growth factor receptor (EGFR) has changed the therapeutic approach and prognosis of non-small cell lung cancer (NSCLC). The effectiveness of tyrosine kinase inhibitors (TKI) has been demonstrated orally in patients with EGFR mutation. We report the case of a patient for whom treatment with TKI was started effectively in a Critical Care Unit. OBSERVATION: A patient of 59 years is followed for a stage IV lung adenocarcinoma with metastases in liver, brain, adrenal, lung and pleura...
April 12, 2017: Revue de Pneumologie Clinique
https://www.readbyqxmd.com/read/28406782/physical-manipulation-of-larynx-as-a-technique-for-insertion-of-nasogastric-tube
#8
Sheema Siraj, Mehmood Mian, Fauzia Anis Khan
No abstract text is available yet for this article.
March 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28377389/relative-bioavailability-of-single-doses-of-prolonged-release-tacrolimus-administered-as-a-suspension-orally-or-via-a-nasogastric-tube-compared-with-intact-capsules-a-phase-1-study-in-healthy-participants
#9
Nasrullah Undre, James Dickinson
OBJECTIVE: Tacrolimus, an immunosuppressant widely used in solid organ transplantation, is available as a prolonged-release capsule for once-daily oral administration. In the immediate postsurgical period, if patients cannot take intact capsules orally, tacrolimus therapy is often initiated as a suspension of the capsule contents, delivered orally or via a nasogastric tube. This study evaluated the relative bioavailability of prolonged-release tacrolimus suspension versus intact capsules in healthy participants...
April 4, 2017: BMJ Open
https://www.readbyqxmd.com/read/28376549/incidence-of-nasogastric-and-gastrostomy-tube-at-discharge-is-reduced-after-implementing-an-oral-feeding-protocol-in-premature-%C3%A2-30-weeks-infants
#10
Michael D Kamitsuka, Patricia A Nervik, Shana L Nielsen, Reese H Clark
Objective Reduce the number of infants requiring home tube feeds by initiating an oral feeding protocol (OFP). Study Design All infants < 30 weeks' gestation were eligible. The OFP involved four steps: encourage non-nutritive suck before 30 weeks, oral motor exercises starting as early as 30 weeks, swallowing exercises as early as 31 weeks, and an infant-driven oral feeding pathway as early as 32 weeks. Results The study included 129 infants before the protocol (January 2010 to December 2011) and 141 infants after the protocol (March 2013 to May 2015)...
May 2017: American Journal of Perinatology
https://www.readbyqxmd.com/read/28375472/enhanced-recovery-after-surgery-protocol-in-patients-undergoing-esophagectomy-for-cancer-a-single-center-experience
#11
S Giacopuzzi, J Weindelmayer, E Treppiedi, M Bencivenga, M Ceola, S Priolo, M Carlini, G de Manzoni
This article is about an emerging issue in esophageal surgery: enhanced recovery after surgery (ERAS) Few data are published in literature and its safety and feasibility is still debated. The focus of our paper is on the feasibility of an ERAS protocol for esophagectomy (including both the Ivor-Lewis and McKeown procedure) in a high volume center comparing to a standard perioperative protocol. We introduced a novelty item on this type of surgery: resume of oral feeding in the first postoperative day. We analyzed the dropout rate for each item and the postoperative morbidity...
April 1, 2017: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/28362572/indicators-for-enteral-nutrition-use-and-prophylactic-percutaneous-endoscopic-gastrostomy-placement-in-patients-with-head-and-neck-cancer-undergoing-chemoradiotherapy
#12
Nina C van der Linden, Annemieke Kok, Marja J Leermakers-Vermeer, Nicole M de Roos, Remco de Bree, Hester van Cruijsen, Chris H J Terhaard
BACKGROUND: Chemoradiotherapy (CRT) is a major risk factor for malnutrition and dehydration in patients with head and neck cancer. Enteral support is often needed, and a percutaneous endoscopic gastrostomy (PEG) is frequently placed. Specific indicators for PEG placement remain unclear. This study retrospectively determined which factors contributed to enteral nutrition (EN) use and PEG placement in a large patient group to gain insight on potential indicators for PEG placement protocol creation...
April 2017: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/28359986/diagnostic-accuracy-of-ultrasonography-for-detecting-nasogastric-tube-ngt-placement-in-adults-a-systematic-review-and-meta-analysis
#13
REVIEW
Tian Lin, Wendy Gifford, Yutao Lan, Xiuqun Qin, Xuelian Liu, Juan Wang, Biping Yang, Tianhui You, Ken Chen
OBJECTIVE: To review the evidence on diagnostic accuracy of ultrasonography for detecting correct nasogastric tube (NGT) placement in adults compared to X-ray as the reference standard. METHODS: This is a systematic review and meta-analysis of observational studies, searched in the literature between 1961 and 2015. We included studies which compared the diagnostic accuracy of ultrasonography detection for NGT placement with X-ray in adult patients who were undergoing NGT placement for any reason in any care setting...
March 9, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/28359362/real-time-image-guided-nasogastric-feeding-tube-placement-a-case-series-using-kangaroo-with-iris-technology-in-an-icu
#14
Anna Mizzi, Silvano Cozzi, Luigi Beretta, Massimiliano Greco, Marco Braga
OBJECTIVE: Pulmonary misplacement during the blind insertion of enteral feeding tubes is frequent, particularly in ventilated and neurologically impaired patients. This is probably the first clinical study using the Kangaroo Feeding Tube with IRIS technology (IRIS) which incorporates a camera designed to provide anatomic landmark visualization during insertion. The study aim was to evaluate IRIS performance during bedside gastric placement. METHODS: This is the first prospective study to collect data on the use of IRIS...
May 2017: Nutrition
https://www.readbyqxmd.com/read/28352063/erythromycin-infusion-prior-to-endoscopy-for-acute-nonvariceal-upper-gastrointestinal-bleeding-a-pilot-randomized-controlled-trial
#15
Hee Kyong Na, Hwoon-Yong Jung, Dong Woo Seo, Hyun Lim, Ji Yong Ahn, Jeong Hoon Lee, Do Hoon Kim, Kee Don Choi, Ho June Song, Gin Hyug Lee, Jin-Ho Kim
Background/Aims: The aim of this study was to compare the effects of erythromycin infusion and gastric lavage in order to improve the quality of visualization during emergency upper endoscopy. Methods: We performed a prospective randomized pilot study. Patients presented with hematemesis or melena within 12 hours and were randomly assigned to the erythromycin group (intravenous infusion of erythromycin), gastric lavage group (nasogastric tube placement with gastric lavage), or erythromycin + gastric lavage group (both erythromycin infusion and gastric lavage)...
March 28, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/28349318/laparoscopic-versus-open-resection-for-gastric-gastrointestinal-stromal-tumors-gists-a-size-location-matched-case-control-study
#16
Jun-Lin Chi, Mao Xu, Ming-Ran Zhang, Yuan Li, Zong-Guang Zhou
BACKGROUND: Laparoscopic resection for gastric gastrointestinal stromal tumors (GISTs) is technically feasible, but the long-term effect remains uncertain. This study aims to compare the long-term oncologic outcomes of laparoscopic versus open resection of GISTs by larger cases based on tumor size-location-matched study. METHODS: Between 2006 and 2015, 63 consecutive patients with a primary gastric GIST undergoing laparoscopic resection were enrolled in and matched (1:1) to patients undergoing open resection by tumor size and location...
March 27, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28341473/pneumonia-after-cardiac-surgery-experience-of-the-national-institutes-of-health-canadian-institutes-of-health-research-cardiothoracic-surgical-trials-network
#17
Gorav Ailawadi, Helena L Chang, Patrick T O'Gara, Karen O'Sullivan, Y Joseph Woo, Joseph J DeRose, Michael K Parides, Vinod H Thourani, Sophie Robichaud, A Marc Gillinov, Wendy C Taddei-Peters, Marissa A Miller, Louis P Perrault, Robert L Smith, Lyn Goldsmith, Keith A Horvath, Kristen Doud, Kim Baio, Annetine C Gelijns, Alan J Moskowitz, Emilia Bagiella, John H Alexander, Alexander Iribarne
RATIONALE: Pneumonia remains the most common major infection after cardiac surgery despite numerous preventive measures. OBJECTIVES: To prospectively examine the timing, pathogens, and risk factors, including modifiable management practices, for postoperative pneumonia and estimate its impact on clinical outcomes. METHODS: A total of 5158 adult cardiac surgery patients were enrolled prospectively in a cohort study across 10 centers. All infections were adjudicated by an independent committee...
February 9, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28328824/early-use-of-noninvasive-techniques-for-clearing-respiratory-secretions-during-noninvasive-positive-pressure-ventilation-in-patients-with-acute-exacerbation-of-chronic-obstructive-pulmonary-disease-and-hypercapnic-encephalopathy-a-prospective-cohort-study
#18
Jinrong Wang, Zhaobo Cui, Shuhong Liu, Xiuling Gao, Pan Gao, Yi Shi, Shufen Guo, Peipei Li
Noninvasive positive-pressure ventilation (NPPV) might be superior to conventional mechanical ventilation (CMV) in patients with acute exacerbations of chronic obstructive pulmonary disease (AECOPDs). Inefficient clearance of respiratory secretions provokes NPPV failure in patients with hypercapnic encephalopathy (HE). This study compared CMV and NPPV combined with a noninvasive strategy for clearing secretions in HE and AECOPD patients.The present study is a prospective cohort study of AECOPD and HE patients enrolled between October 2013 and August 2015 in a critical care unit of a major university teaching hospital in China...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28324468/ascariasis-and-hyperosmolar-hyperglycemic-state-a-surprising-ultrasound-finding-in-the-emergency-department
#19
Giles N Cattermole, Jean-Paul Nzabandora
BACKGROUND: We report the ultrasound finding of ascariasis in a patient with hyperosmolar hyperglycemic state (HHS). Although ascariasis is common in low-resource settings, there has been no previous report associating ascariasis with HHS. CASE PRESENTATION: A 26-year-old Rwandan man was admitted to the emergency department in coma, with a glycemia of 600 mg/dl. He was resuscitated with fluids, intubated and ventilated, and treated with insulin and antibiotics...
December 2017: International Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28322006/aspiration-and-dysphagia-screening-in-acute-stroke-the-gugging-swallowing-screen-revisited
#20
T Warnecke, S Im, C Kaiser, C Hamacher, S Oelenberg, R Dziewas
BACKGROUND AND PURPOSE: The Gugging Swallowing Screen (GUSS) is a tool to screen aspiration risk in acute stroke. We aimed to replicate its validity in a larger second cohort of patients with acute stroke, including the more severe with a National Institutes of Health Stroke Scale (NIHSS) ≥ 15. METHODS: In a prospective, double-blind design, the GUSS was validated with the Fiberoptic Endoscopic Evaluation of Swallowing scale. Patients were categorized into different stroke severities as assessed by the NIHSS, and the diagnostic properties were calculated separately for each subgroup...
April 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
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