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https://www.readbyqxmd.com/read/28226720/comparison-of-viscoelastic-property-characterization-of-plastisol-phantoms-with-magnetic-resonance-elastography-and-high-frequency-rheometry
#1
P M Lefebvre, K Tse Ve Koon, E Brusseau, S Nicolle, J-F Palieme, S A Lambert, D Grenier, P M Lefebvre, K Tse Ve Koon, E Brusseau, S Nicolle, J-F Palieme, S A Lambert, D Grenier, P M Lefebvre, E Brusseau, S Nicolle, D Grenier, S A Lambert
This study aims at evaluating Magnetic Resonance Elastography (MRE) as a reliable technique for the characterization of viscoelastic properties of soft tissues. Three phantoms with different concentrations of plastisol and softener were prepared in order to mechanically mimic a broad panel of healthy and pathological soft tissues. Once placed in a MRI device, each sample was excited by a homemade external driver, inducing shear waves within the medium. The storage (G') and loss (G") moduli of each phantom were then reconstructed from MRE acquisitions over a frequency range from 300 to 1,000 Hz, by applying a 2D Helmholtz inversion algorithm...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28225916/expression-profiles-of-enos-inos-and-microrna-27b-in-the-corpus-cavernosum-of-rats-submitted-to-chronic-alcoholism-and-diabetes-mellitus
#2
Joao Paulo da Cunha, Fermino Sanches Lizarte, Paulo Cezar Novais, Daniela Gattas, Camila Albuquerque Mello de Carvalho, Daniela Pretti da Cunha Tirapelli, Carlos Augusto Fernandes Molina, Luis Fernando Tirapelli, Silvio Tucci
Purpose: To evaluate the expression of endothelial and inducible NOS in addition to the miRNA-27b in the corpus cavernosum and peripheral blood of healthy rats, diabetic rats, alcoholic rats and rats with both pathologies. Methods: Forty eight Wistar rats were divided into four groups: control (C), alcoholic (A), diabetic (D) and alcoholic-diabetic (AD). Samples of the corpus cavernosum were prepared to study protein expressions of eNOS and iNOS by immunohistochemistry and expression of miRNA-27b in the corpus cavernosum and peripheral blood...
January 2017: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/28224898/non-covalently-crosslinked-chitosan-nanofibrous-mats-prepared-by-electrospinning-as-substrates-for-soft-tissue-regeneration
#3
Chiara Tonda-Turo, Francesca Ruini, Martina Ramella, Francesca Boccafoschi, Piergiorgio Gentile, Emilia Gioffredi, Giuseppe Falvo D'Urso Labate, Gianluca Ciardelli
Chitosan (CS) membranes obtained by electrospinning are potentially ideal substrates for soft tissue engineering as they combine the excellent biological properties of CS with the extracellular matrix (ECM)-like structure of nanofibrous mats. However, the high amount of acid solvents required to spun CS solutions interferes with the biocompatibility of CS fibres. To overcome this limitation, novel CS based solutions were investigated in this work. Low amount of acidic acid (0.5M) was used and dibasic sodium phosphate (DSP) was introduced as ionic crosslinker to improve nanofibres water stability and to neutralize the acidic pH of electrospun membranes after fibres soaking in biological fluids...
April 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28224896/carboxylmethyl-konjac-glucomannan-conjugated-polydopamine-composites-for-pb-ii-removal
#4
Pan-Pan Chen, Hong-Ping Zhang, Jianping Ding, Xiao-Yan Lin, Xiong Lu, Changsheng Liu, Youhong Tang
Carboxylmethyl konjac glucomannan conjugated polydopamine (CMKGM-PDA) composite was successfully prepared using a cost-effective method. CMKGM-PDA exhibited excellent adsorption performance for the removal of Pb(II) and could be a convenient agent for recovery. The Langmuir linear model was suitable for describing the adsorption process of Pb(II). The maximum adsorption capacity was 95.24mgg(-1) at 298K, showing a high absorption capacity in comparison to similar absorbents. The pseudo-second order equation and intra-particle diffusion model exhibited good correlation with the adsorption kinetic...
April 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28224893/influence-of-molecular-weight-and-structure-on-diffusion-rates-and-mechanisms-of-dextran-polyelectrolyte-complexes
#5
Yasunori Miyazaki, Midori Mieno, Tomonobu Uchino, Yoshiyuki Kagawa
The release profiles of fluorescein isothiocyanate-dextran (FD) at various molecular weights (20-500kDa) and the swelling behaviors of polyelectrolyte complex-forming tablets were investigated. Four types of tablets were prepared using different combinations of the following chemicals: carboxymethyl dextran (CMD), dextran sulfate (DS), 2-diethylaminoethyl dextran (EA), and 2-hydroxypropyltrimethylammonium dextran (CDC). Release tests were conducted via the rotating basket method at pH 6.8. Swelling behaviors were analyzed via the front movement method...
April 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28224246/comparison-of-veterinary-drug-residue-results-in-animal-tissues-by-ultrahigh-performance-liquid-chromatography-coupled-to-triple-quadrupole-or-quadrupole-time-of-flight-tandem-mass-spectrometry-after-different-sample-preparation-methods-including-use-of-a-commercial
#6
Tarun Anumol, Steven J Lehotay, Joan Stevens, Jerry Zweigenbaum
Veterinary drug residues in animal-derived foods must be monitored to ensure food safety, verify proper veterinary practices, enforce legal limits in domestic and imported foods, and for other purposes. A common goal in drug residue analysis in foods is to achieve acceptable monitoring results for as many analytes as possible, with higher priority given to the drugs of most concern, in an efficient and robust manner. The U.S. Department of Agriculture has implemented a multiclass, multi-residue method based on sample preparation using dispersive solid phase extraction (d-SPE) for cleanup and ultrahigh-performance liquid chromatography-tandem quadrupole mass spectrometry (UHPLC-QQQ) for analysis of >120 drugs at regulatory levels of concern in animal tissues...
February 21, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28224244/preparation-of-magnetic-melamine-formaldehyde-resin-and-its-application-to-extract-nonsteroidal-anti-inflammatory-drugs
#7
Shu-Wen Xue, Jing Li, Li Xu
Magnetic melamine-formaldehyde resin was prepared via water-in-oil emulsification approach by entrapping Fe3O4 magnetic nanoparticles as the core. The preparation of the magnetic resin was optimized by investigating the amount of polyethylene glycol 20000 and Fe3O4 nanoparticles, the concentration of the catalyst (hydrochloric acid), as well as the mechanical stirring rate. The prepared material was characteristic of excellent anion-exchange capacity, good water wettability, and proper magnetism. Its application was demonstrated by magnetic solid-phase extraction of nonsteroidal anti-inflammatory drugs coupled to high performance liquid chromatography-UV analysis...
February 21, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28223860/polymeric-films-as-a-promising-carrier-for-bioadhesive-drug-delivery-development-characterization-and-optimization
#8
Pallavi Bassi, Gurpreet Kaur
Bioadhesive films using tamarind seed polysaccharide were prepared for the treatment of candida vaginitis using nystatin as the model drug. Films were prepared by solvent casting method. A 3(2) factorial design was employed to study the effect of independent variables (polymer and plasticizer concentration) on a range of dependent variables namely mechanical, swelling, interfacial, and bioadhesive properties through response surface methodological approach, using Design Expert® software. Formulation composition that provided the most desired and optimized results was selected using desirability approach...
January 2017: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://www.readbyqxmd.com/read/28222907/fatigue-testing-of-biomaterials-and-their-interfaces
#9
Dwayne Arola
OBJECTIVE: The objective of this article is to describe the importance of fatigue to the success of restorative dentistry, with emphasis on the methods for evaluating the fatigue properties of materials in this field, and the durability of their bonded interfaces. METHODS: The stress-life fatigue and fatigue crack growth approaches for evaluating the fatigue resistance of dental biomaterials are introduced. Emphasis is placed on in vitro studies of the hard tissue foundation, restorative materials and their bonded interfaces...
February 17, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28222304/fabrication-of-novel-visible-light-driven-agi-g-c3n4-composites-with-enhanced-visible-light-photocatalytic-activity-for-diclofenac-degradation
#10
Wei Zhang, Li Zhou, Jun Shi, Huiping Deng
A visible-light-driven heterostructured AgI/g-C3N4 was prepared by a deposition-precipitation method. The composition, structure, morphology, and optical properties of the photocatalyst were characterized by Brunauer-Emmett-Teller method (BET), X-ray powder diffraction (XRD), Fourier transform-infrared spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS), transmission electron microscope (TEM), scanning electron microscope (SEM), UV-vis diffused reflectance spectroscopy (DRS), photoluminescence spectroscopy (PL), photocurrent, and electrochemical impedance spectroscopy (EIS), respectively...
February 14, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28222303/organic-dye-removal-from-aqueous-solutions-by-hierarchical-calcined-ni-fe-layered-double-hydroxide-isotherm-kinetic-and-mechanism-studies
#11
Chunsheng Lei, Meng Pi, Panyong Kuang, Yingqing Guo, Fenge Zhang
Hierarchically porous nickel-iron-layered double hydroxide (NiFe-LDH) with a Ni(2+)/Fe(3+) molar ratio of 3 was successfully synthesised through a simple hydrothermal route. After calcination at 400°C, NiFe-LDH transformed into nickel-iron-layered double oxides (NiFe-LDO). The as-prepared samples were characterised through X-ray powder diffraction, field emission scanning electron microscopy, energy dispersive X-ray spectroscopy, Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy and nitrogen adsorption...
February 14, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28222262/a-nature-inspired-strategy-toward-superhydrophobic-fabrics-for-versatile-oil-water-separation
#12
Cailong Zhou, Zhaodan Chen, Hao Yang, Kun Hou, Xinjuan Zeng, Yanfen Zheng, Jiang Cheng
Phytic acid, a naturally occurring component, widely found in many plants, can strongly bond toxic mineral elements in human body due to its six phosphate groups. Some of the metal ions present the property of bonding with phytic acid to form insoluble coordination complexes aggregations even in room temperature. Herein, a superhydrophobic cotton fabric was prepared by a novel and facile nature-inspired strategy which introduced phytic acid metal complexes aggregations to generate rough hierarchical structures on fabric surface followed with PDMS modification...
February 21, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28221748/fe3-ph-thermo-responsive-supramolecular-hydrogel-with-multi-shape-memory-effect
#13
Xiaoxia Le, Wei Lu, He Xiao, Li Wang, Chunxin Ma, Jiawei Zhang, Youju Huang, Tao Chen
Poor, non-tunable mechanical properties as well as finite shape memory performance pose a barrier to shape memory hydrogels to realize practical applications. Here, a new shape memory hydrogel with tunable mechanical properties and multi-shape memory effect was presented. Three programmable reversible systems including PBA-diol ester bonds, AAc-Fe3+ and coil-helix transition of agar were applied to memorize temporary shapes and endow the hydrogel with outstanding multi-shape memory functionalities. Moreover, through changing the crosslinking densities, the mechanical properties of the as-prepared hydrogel can be adjusted...
February 21, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28221717/cerebral-and-lung-effects-of-a-new-generation-synthetic-surfactant-with-sp-b-and-sp-c-analogs-in-preterm-lambs
#14
Carmen Rey-Santano, Victoria E Mielgo, Xabier Murgia, Miguel Angel Gomez-Solaetxe, Fabrizio Salomone, Federico Bianco, Nicola Pelizzi, Begoña Loureiro, Jon López de Heredia Y Goya
BACKGROUND: Though natural surfactants (SF) are clinically superior to protein-free synthetic preparations, CHF-5633, a synthetic SF containing SP-B and SP-C analog peptides is a potential alternative to natural SF for treating neonatal respiratory distress syndrome (RDS). Nevertheless, information is lacking regarding the safety of this new treatment for the neonatal brain. We sought to compare the cerebral and pulmonary effects of this new synthetic surfactant (CHF5633) with those of natural porcine surfactant (Cursosurf) in premature lambs with RDS...
February 21, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/28220960/a-comparative-investigation-of-bombyx-mori-silk-fibroin-hydrogels-generated-by-chemical-and-enzymatic-crosslinking
#15
Traian V Chirila, Shuko Suzuki, Chloé Papolla
Fibroin, the major proteinaceous component of the silk fiber produced by larvae of the domesticated silk moth (Bombyx mori), has been widely investigated as a biomaterial for potential applications in tissue engineering and regenerative medicine. Following sol-gel transition, silk fibroin solutions can generate hydrogels that present certain advantages when employed as biomaterials, especially if they are crosslinked. The subject of this study was the self-crosslinking of silk fibroin through a process induced by the enzyme horseradish peroxidase (HRP) in the presence of hydrogen peroxide, a method only recently proposed and scarcely reported...
February 21, 2017: Biotechnology and Applied Biochemistry
https://www.readbyqxmd.com/read/28220385/selective-adsorption-and-recycle-of-cu-2-from-aqueous-solution-by-modified-sugarcane-bagasse-under-dynamic-condition
#16
Jia-Dong Chen, Jun-Xia Yu, Fen Wang, Jia-Qi Tang, Yue-Fei Zhang, Yuan-Lai Xu, Ru-An Chi
Tetraethylenepentamine modified sugarcane bagasse was prepared and applied to test its feasibility in removing and recovering Cu(2+) from wastewater under dynamic condition. Results showed that the Cu(2+) could be selectively absorbed from wastewater by the modified SCB fixed bed column. To understand the adsorption mechanism, Cd(2+) had been selected as the model interfering ion to investigate how co-ions influence the adsorption of Cu(2+) on the sorbent. It was observed that the adsorption capacity of the sorbent for Cu(2+) (0...
February 20, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28220175/a-mechanically-robust-hydrogel-with-thermally-induced-plasticity-and-a-shape-memory-effect
#17
Kang Peng, Hansen Yu, Haiyang Yang, Xiang Hao, Akram Yasin, Xingyuan Zhang
A new class of smart structural hydrogels is prepared by introducing dual cross-linkers into a single-network system. The present hydrogel, on the one hand, exhibits excellent mechanical properties; on the other hand, it exhibits thermally induced plasticity and a shape memory effect without any overlap.
February 21, 2017: Soft Matter
https://www.readbyqxmd.com/read/28219807/setd2-is-associated-with-strontium-induced-bone-regeneration
#18
Jia Xiaoshi, Long Qiaoyun, Richard J Miron, Yin Chengcheng, Wei Yan, Zhang Yufeng, Wu Min
: Strontium Ranelate has been utilized as a preventative treatment option for osteoporosis with the release of Sr ions having a direct effect on preventing osteoclast activation and promoting osteoblast differentiation. Previously our group has prepared and characterized a porous Sr-mesoporous bioactive glass (Sr-MBG) scaffold demonstrating its ability to enhance new bone formation when compared to MBG alone. The goal of the present study was to elucidate the bone-inducing properties of Sr by utilizing RNA-seq on in vivo tissue samples to investigate potential target genes responsible for Sr-induced new bone formation...
February 17, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28219790/subunit-specific-synaptic-delivery-of-ampa-receptors-by-auxiliary-chaperone-proteins-tarp%C3%AE-8-and-gsg1l-in-classical-conditioning
#19
Joyce Keifer, Neeraj K Tiwari, Leah Buse, Zhaoqing Zheng
AMPA receptor (AMPAR) trafficking has emerged as a fundamental concept for understanding mechanisms of learning and memory as well as many neurological disorders. Classical conditioning is a simple and highly conserved form of associative learning. Our studies use an ex vivo brainstem preparation in which to study cellular mechanisms underlying learning during a neural correlate of eyeblink conditioning. Two stages of AMPAR synaptic delivery underlie conditioning utilizing sequential trafficking of GluA1-containing AMPARs early in conditioning followed by replacement with GluA4 subunits later...
February 17, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28219750/release-kinetics-of-highly-porous-floating-tablets-containing-cilostazol
#20
Kyu-Mok Hwang, Cheol-Hee Cho, Nguyen-Thach Tung, Ju-Young Kim, Yun-Seok Rhee, Eun-Seok Park
This study focuses on developing a highly porous floating tablet containing cilostazol. The underlying release mechanism of cilostazol from porous and floating tablets in dissolution media containing surfactants was investigated. The tablets were prepared by compressing granules and excipients with a sublimating agent, followed by sublimation under vacuum. The volatile material for the sublimating agent was chosen based on its flow properties using conventional methods as well as the twisted blade method. Resultant tablets could float immediately and had significantly higher tensile strengths than conventional tablets of similar porosities, holding a promising potential for increasing gastroretentive properties...
February 17, 2017: European Journal of Pharmaceutics and Biopharmaceutics
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