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https://www.readbyqxmd.com/read/28110407/in-vitro-performance-of-cad-cam-fabricated-implant-supported-temporary-crowns
#1
Martin Rosentritt, Philipp Raab, Sebastian Hahnel, Matthias Stöckle, Verena Preis
OBJECTIVES: The aim of this study was to investigate the in-vitro performance and fracture resistance of a temporary computer-aided designed and computer-aided manufactured polymethylmethacrylate (CAD/CAM-PMMA) material as implant or tooth-supported single crown with respect to the clinical procedure (permanently bonded/temporarily cemented). MATERIALS AND METHODS: Sixty-four crowns were fabricated on implants or human molar teeth simulating (a) labside procedure on prefabricated titanium-bonding base ([TiBase] implant crown bonded in laboratory, screwed chairside), (b) labside procedure ([LAB] standard abutment and implant crown bonded in laboratory, screwed chairside), (c) chairside procedure ([CHAIR] implant crown bonded to abutment), and (d) reference ([TOOTH] crowns luted on prepared human teeth)...
January 21, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28110178/tem-sample-preparation-by-femtosecond-laser-machining-and-ion-milling-for-high-rate-tem-straining-experiments
#2
Thomas Voisin, Michael D Grapes, Yong Zhang, Nicholas Lorenzo, Jonathan Ligda, Brian Schuster, Timothy P Weihs
To model mechanical properties of metals at high strain rates, it is important to visualize and understand their deformation at the nanoscale. Unlike post mortem Transmission Electron Microscopy (TEM), which allows one to analyze defects within samples before or after deformation, in situ TEM is a powerful tool that enables imaging and recording of deformation and the associated defect motion during mechanical loading. Unfortunately, all current in situ TEM mechanical testing techniques are limited to quasi-static strain rates...
December 5, 2016: Ultramicroscopy
https://www.readbyqxmd.com/read/28110085/encoding-preparation-and-implementation-of-novel-complex-verbal-instructions
#3
Carlos González-García, Juan E Arco, Ana F Palenciano, Javier Ramírez, María Ruz
Verbal instructions allow humans to acquire and implement complex novel rules in few seconds. A major question that remains elusive is how the brain represents this information prior to successful task execution. In this experiment, we studied the brain regions involved in representing categorical stimulus information during the encoding of novel instructions, their preparation and also their implementation, as well as the relation of the fidelity of these representations to observable behavior. To do so, we devised a novel instructions paradigm to delimitate these three stages...
January 18, 2017: NeuroImage
https://www.readbyqxmd.com/read/28110038/enhancement-of-magnetofection-efficiency-using-chitosan-coated-superparamagnetic-iron-oxide-nanoparticles-and-calf-thymus-dna
#4
Z Sohrabijam, M Saeidifar, A Zamanian
Superparamagnetic iron oxide nanoparticles (MNPs) were prepared and coated with chitosan (CS). The chitosan-magnetic iron oxide nanoparticles (CS-MNPs) were characterized using Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), vibrating sample magnetometry (VSM), and the morphology of the particles was studied by transmission electron microscopy (TEM). Our findings show that the magnetic particles were monodisperse (10nm mean diameter) and exhibited superparamagnetic behavior. The interaction between the particles and calf-thymus DNA (DNA) in physiological buffer was studied with UV-vis, fluorescence and circular dichroism spectroscopy and zeta potential...
January 17, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28109901/study-of-ciprofloxacin-adsorption-and-regeneration-of-activated-carbon-prepared-from-enteromorpha-prolifera-impregnated-with-h3po4-and-sodium-benzenesulfonate
#5
Man Wang, Gang Li, Lihui Huang, Jing Xue, Quan Liu, Nan Bao, Ji Huang
Activated carbons were derived from Enteromorpha prolifera immersed in H3PO4 solution or the H3PO4 solution mixed with sodium benzenesulfonate (SBS), producing AC and AC-SBS. NaOH solution was employed in regeneration of ciprofloxacin (CIP)-loaded AC and AC-SBS to obtain RAC and RAC-SBS. The properties of the original and regenerated activated carbons were characterized by thermo-gravimetric analysis (TGA), scanning electron microscopy (SEM), N2 adsorption/desorption isotherms and Fourier transform infrared spectroscopy (FTIR)...
January 18, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28109897/simulation-and-evaluation-of-rupturable-coated-capsules-by-finite-element-method
#6
Yan Yang, Jie Fang, Lian Shen, Weiguang Shan
The objective of this study was to simulate and evaluate the burst behavior of rupturable coated capsules by finite element method (FEM). Film and coated capsules were prepared by dip-coating method and their dimensions were determined by stereomicroscope. Mechanical properties of the film were measured by tensile test and used as material properties of FEM models. Swelling pressure was determined by restrained expansion method and applied to the internal surface of FEM models. Water uptake of coated capsules was determined to study the formation of internal pressure...
January 18, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28109814/carboxymethyl-sesbania-gum-synthesis-characterization-and-evaluation-for-drug-delivery
#7
Shakuntla Verma, Munish Ahuja
In the present study, carboxymethyl Sesbania gum was synthesized and evaluated for drug delivery. Carboxymethylation was carried out by reacting with monochloroacetic acid under alkaline conditions. Modification of the gum was confirmed by Fourier-transform infrared spectroscopy. The degree of carboxymethyl substitution was determined to be 1.3. Carboxymethylation improved the flow properties, increased the degree of crystallinity and changed the compression behaviour from elastic to plastic. Further, the interaction between the modified gum and Ca(2+)-ions was optimized employing a 3-factor, 3-level central composite experimental design to prepare mucoadhesive sustained release beads using metformin hydrochloride as the model drug...
January 18, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28109810/thermal-mechanical-and-physical-properties-of-seaweed-sugar-palm-fibre-reinforced-thermoplastic-sugar-palm-starch-agar-hybrid-composites
#8
Ridhwan Jumaidin, Salit M Sapuan, Mohammad Jawaid, Mohamad R Ishak, Japar Sahari
The aim of this research is to investigate the effect of sugar palm fibre (SPF) on the mechanical, thermal and physical properties of seaweed/thermoplastic sugar palm starch agar (TPSA) composites. Hybridized seaweed/SPF filler at weight ratio of 25:75, 50:50 and 75:25 were prepared using TPSA as a matrix. Mechanical, thermal and physical properties of hybrid composites were carried out. Obtained results indicated that hybrid composites display improved tensile and flexural properties accompanied with lower impact resistance...
January 18, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28109413/biobehavioral-factors-that-shape-nutrition-in-low-income-populations-a-narrative-review
#9
EDITORIAL
Barbara A Laraia, Tashara M Leak, June M Tester, Cindy W Leung
Although evidence exists for an association between income level and diet quality, a causal relationship has not been established. A number of studies found that the price of nutritious food and the time cost to prepare foods are economically driven reasons for this relationship. However, in addition to economic constraints, low-income individuals and families face a number of additional challenges linked with food choice, eating behaviors, and diet-related chronic conditions that contribute to diet quality and health...
February 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28109303/uptake-of-dna-by-cancer-cells-without-a-transfection-reagent
#10
Yanping Kong, Xianbo Zhang, Yongliang Zhao, Yanfang Xue, Ye Zhang
BACKGROUND: Cancer cells exhibit elevated levels of glucose uptake and may obtain pre-formed, diet-derived fatty acids from the bloodstream to boost their rapid growth; they may also use nucleic acid from their microenvironment. The study of processing nucleic acid by cancer cells will help improve the understanding of the metabolism of cancer. DNA is commonly packaged into a viral or lipid particle to be transferred into cells; this process is called transfection in laboratory. Cancer cells are known for having gene mutations and the evolving ability of endocytosis...
January 21, 2017: Biological Research
https://www.readbyqxmd.com/read/28109139/-imiquimod-combined-with-dendritic-cell-vaccine-decreases-treg-proportion-and-enhances-anti-tumor-responses-in-mice-bearing-melanoma
#11
Shurong Ren, Qiubo Wang, Yanli Zhang, Cuixiu Lu, Ping Li, Yumei Li
Objective To investigate the therapeutic effect of Toll-like receptor 7 (TLR7) agonist imiquimod combined with dendritic cell (DC)-based tumor vaccine on melanoma in mice and the potential mechanism. Methods Melanoma-bearing mouse models were established by subcutanous injection of B16-OVA cells into C57BL/6 mice. DCs were isolated from mouse bone marrow and propagated in culture medium with recombinant mouse granulocyte-macrophage colony-stimulating factor (rmGM-CSF) and recombinant mouse interleukin-4 (rmIL-4)...
February 2017: Xi Bao Yu Fen Zi Mian Yi Xue za Zhi, Chinese Journal of Cellular and Molecular Immunology
https://www.readbyqxmd.com/read/28109092/-early-outcomes-of-elective-surgery-for-colon-cancer-with-preoperative-mechanical-bowel-preparation-a-randomized-clinical-trial
#12
Yan-Jie Hu, Ka Li, Li Li, Xiao-Dong Wang, Jie Yang, Jin-Hua Feng, Wei Zhang, Yu-Wei Liu
OBJECTIVE: To compared the early outcomes of patients undergoing elective surgeries for colon cancer with and without preoperative mechanical bowel preparation. METHODS: Between July, 2014 and February, 2016, patients undergoing elective surgery for colon cancer with primary anastomosis were randomly assigned into control group with mechanical bowel preparation 12 h before surgery and treatment group without mechanical bowel preparation. Baseline data collection was completed within 12 h after the operation...
January 20, 2017: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/28108973/development-and-evaluation-of-buccal-films-based-on-chitosan-for-the-potential-treatment-of-oral-candidiasis
#13
G Tejada, M G Barrera, G N Piccirilli, M Sortino, A Frattini, C J Salomón, María C Lamas, Darío Leonardi
In this work, chitosan films were prepared by a casting/solvent evaporation methodology using pectin or hydroxypropylmethyl cellulose to form polymeric matrices. Miconazole nitrate, as a model drug, was loaded into such formulations. These polymeric films were characterized in terms of mechanical properties, adhesiveness, and swelling as well as drug release. Besides, the morphology of raw materials and films was investigated by scanning electron microscopy; interactions between polymers were analyzed by infrared spectroscopy and drug crystallinity studied by differential scanning calorimetry and X-ray diffraction...
January 20, 2017: AAPS PharmSciTech
https://www.readbyqxmd.com/read/28108532/tdp-43-prions
#14
Takashi Nonaka, Masato Hasegawa
The most common neurodegenerative diseases, such as Alzheimer's, Parkinson's, and amyotrophic lateral sclerosis, are all protein-misfolding diseases and are characterized by the presence of disease-specific protein aggregates in affected neuronal cells. Recent studies have shown that, like tau and α-synuclein, TAR-DNA binding protein of 43 kDa (TDP-43) can form aggregates in vitro in a seed-dependent, self-templating, prion-like manner. Insoluble TDP-43 prepared from the brains of patients has been classified into several strains, which can be transferred from cell to cell in vitro, suggesting the involvement of mechanisms reminiscent of those by which prions spread through the nervous system...
January 20, 2017: Cold Spring Harbor Perspectives in Medicine
https://www.readbyqxmd.com/read/28108173/broach-handle-design-changes-force-distribution-in-the-femur-during-total-hip-arthroplasty
#15
Dustin A Greenhill, Pooyan Abbasi, Kurosh Darvish, Andrew M Star
BACKGROUND: Curved broach handles were developed to overcome limited surgical exposures during total hip arthroplasty. Some authors report increased intraoperative fracture rates during limited exposures. This study evaluates mechanical force ratios transmitted to the bone while broaching with curved vs straight handles. METHODS: An experimental model utilized a 6-axis load cell to measure force distributions produced by 4 different broach handles, each with increasing offset and curvature...
December 29, 2016: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28108079/preparation-and-evaluation-of-pillararene-bonded-silica-gel-stationary-phases-for-high-performance-liquid-chromatography
#16
Wenjie Zhao, Jianxiang Chu, Fuwei Xie, Qunpeng Duan, Lijun He, Shusheng Zhang
Pillararene bonded stationary phases for high performance liquid chromatography were prepared using 3-aminopropyltriethoxysilane as coupling reagent. The structure of the new materials was characterized by infrared spectroscopy, elemental analysis and thermogravimetric analysis. The chromatographic performance and retention mechanism of the new stationary phases were evaluated in reversed-phase mode compared with C18 using different solute probes including Tanaka test solutes, polycyclic aromatic hydrocarbons, phenols and aromatic positional isomers...
December 11, 2016: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28107739/on-the-synthesis-of-nanostructured-akermanite-scaffolds-via-space-holder-method-the-effect-of-the-spacer-size-on-the-porosity-and-mechanical-properties
#17
Aliakbar Najafinezhad, Majid Abdellahi, Sepideh Nasiri-Harchegani, Ali Soheily, Mohammadsaleh Khezri, Hamid Ghayour
In the present study, for the first time, the space holder method was used to prepare akermanite scaffolds with high porous structures, high interconnectivity, and high compressive strength, while the role of different spacer sizes on the akermanite scaffold properties was also evaluated. The results showed that the increase in the NaCl particle size which was used as spacer leads to an increase of the pore size and interconnectivity and a decrease of compressive strength. When the size of the spacer was 420-600µm and more than 600µm, a total porosity of 82 and 83% and a compressive strength of 0...
January 3, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28107616/superhydrophilic-antireflective-periodic-mesoporous-organosilica-coating-on-flexible-polyimide-substrate-with-strong-abrasion-resistance
#18
Jing Wang, Cong Zhang, Chunming Yang, Ce Zhang, Mengchao Wang, Jing Zhang, Yao Xu
Superhydrophilic antireflective periodic mesoporous organosilica (PMO) coating was prepared on flexible polyimide substrate via solvent-evaporation-induced self-assembly (SEISA) method, in which tetraethoxysilane (TEOS) and a special bridged silsesquioxane were used as reactants. The bridged silsesquioxane, EG-BSQ, was synthesized through the stoichiometric reaction between 3-glycidoxyporpyltrimethoxysilane (GPTMS) and ethylene diamine (EDA) at 60 (○)C with no catalyst. Under the influence of surfactant, TEOS and EG-BSQ co-condensed and enclosed the ordered mesporous in the coating...
January 20, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28106930/local-proton-source-in-the-electrocatalytic-co2-reduction-by-mn-bpy-r-co-3br-complexes
#19
Carlo Nervi, Federico Franco, Claudio Cometto, Luca Nencini, Claudia Barolo, Fabrizio Sordello, Claudio Minero, Jan Fiedler, Marc Robert, Roberto Gobetto
The electrochemical behavior of fac-[Mn(pdbpy)(CO)3Br] (pdbpy = 4-phenyl-6-(phenyl-2,6-diol)-2,2'-bipyridine), 1, in acetonitrile under Ar and its catalytic performances for CO2 reduction with added water, 2,2',2''-trifluoroethanol (TFE) and phenol are discussed in detail. Preparative-scale electrolysis experiments, carried out at -1.5 V vs. SCE in CO2-saturated acetonitrile solutions, reveal that the process selectivity is extremely sensitive to the acid strength, providing CO and formate in different faradaic yields...
January 20, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28106786/sulfolobus-acidocaldarius-udg-can-remove-du-from-the-rna-backbone-insight-into-the-specific-recognition-of-uracil-linked-with-deoxyribose
#20
Gang-Shun Yi, Wei-Wei Wang, Wei-Guo Cao, Feng-Ping Wang, Xi-Peng Liu
Sulfolobus acidocaldarius encodes family 4 and 5 uracil-DNA glycosylase (UDG). Two recombinant S. acidocaldarius UDGs (SacUDG) were prepared and biochemically characterized using oligonucleotides carrying a deaminated base. Both SacUDGs can remove deoxyuracil (dU) base from both double-stranded DNA and single-stranded DNA. Interestingly, they can remove U linked with deoxyribose from single-stranded RNA backbone, suggesting that the riboses on the backbone have less effect on the recognition of dU and hydrolysis of the C-N glycosidic bond...
January 18, 2017: Genes
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