Junlai Liu, Xiao Hu, Jie Chen, Xinqi Li, Lu Wang, Binbin Wang, Wenbo Peng, Cuiwei Yang, Zhijie Li, Yan Chen, Yue J Wang, Chuanjiang Li, Xiajun Li, Fang Yan, Yunfang Wang, Changzhen Shang, Xin Wang, Tao Chen, Pengyu Huang
Liver regeneration (LR) happens after various types of injuries. Unlike the well-studied LR caused by partial hepatectomy (PHx), there is accumulating evidence suggesting that LR during other injuries may result from unknown mechanisms. In this study, we found that insulin-like growth factor 2 (IGF-2) was drastically induced following the liver injuries caused by tyrosinemia or long-term treatments of CCl4 . However, this was not observed during the early phase of acute liver injuries after PHx or single treatment of CCl4 ...
December 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases