keyword
https://read.qxmd.com/read/38537225/a-randomized-noninferiority-trial-to-compare-enteral-to-parenteral-phosphate-replacement-on-biochemistry-waste-and-environmental-impact-and-healthcare-cost-in-critically-ill-patients-with-mild-to-moderate-hypophosphatemia
#1
JOURNAL ARTICLE
Chinh D Nguyen, Haustine P Panganiban, Timothy Fazio, Amalia Karahalios, Melissa Akravs, Christopher M MacIsaac, Thomas Rechnitzer, Lucy Arno, An Tran-Duy, Scott McAlister, Yasmine Ali Abdelhamid, Adam M Deane
OBJECTIVES: Hypophosphatemia occurs frequently. Enteral, rather than IV, phosphate replacement may reduce fluid replacement, cost, and waste. DESIGN: Prospective, randomized, parallel group, noninferiority clinical trial. SETTING: Single center, 42-bed state trauma, medical and surgical ICUs, from April 20, 2022, to July 1, 2022. PATIENTS: Patients with serum phosphate concentration between 0.3 and 0.75 mmol/L. INTERVENTIONS: We randomized patients to either enteral or IV phosphate replacement using electronic medical record-embedded program...
March 25, 2024: Critical Care Medicine
https://read.qxmd.com/read/38537124/genetically-identifying-the-thrombo-embolic-in-cteph
#2
JOURNAL ARTICLE
Christina A Eichstaedt
No abstract text is available yet for this article.
March 27, 2024: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/38536423/-optinofa-intelligent-assistance-service-for-structured-assessment-in-the-emergency-department
#3
JOURNAL ARTICLE
Elisabeth Nyoungui, Marina V Karg, Marc Wieckenberg, Katrin Esslinger, Michael Schmucker, Andreas Reiswich, Kai L Antweiler, Tim Friede, Martin Haag, Harald Dormann, Sabine Blaschke
BACKGROUND: Case numbers in central emergency departments (EDs) have risen during the past decade in Germany, leading to recurrent overcrowding, increased risks in emergency care, and elevated costs. Particularly the fraction of outpatient emergency treatments has increased disproportionately. Within the framework of the Optimization of emergency care by structured triage with intelligent assistant service (OPTINOFA, Förderkennzeichen [FKZ] 01NVF17035) project, an intelligent assistance service was developed...
March 27, 2024: Medizinische Klinik, Intensivmedizin und Notfallmedizin
https://read.qxmd.com/read/38536422/-in-memory-of-prof-dr-med-tobias-welte
#4
EDITORIAL
Michael Buerke, Paul Herrmann
No abstract text is available yet for this article.
March 27, 2024: Medizinische Klinik, Intensivmedizin und Notfallmedizin
https://read.qxmd.com/read/38536421/assessing-lung-recruitability-does-it-help-with-peep-settings
#5
EDITORIAL
Luciano Gattinoni, Francesca Collino, Luigi Camporota
No abstract text is available yet for this article.
March 27, 2024: Intensive Care Medicine
https://read.qxmd.com/read/38536165/high-dimensional-mass-cytometry-reveals-emphysema-associated-changes-in-the-pulmonary-immune-system
#6
JOURNAL ARTICLE
Li Jia, Na Li, Tamim R M Abdelaal, Nannan Guo, Marieke E IJsselstein, Vincent van Unen, Ciska Lindelauf, Qinyue Jiang, Yanling Xiao, M Fernanda Pascutti, Pieter S Hiemstra, Frits Koning, Jan Stolk, P Padmini S J Khedoe
RATIONALE: Chronic inflammation plays an important role in alveolar tissue damage in emphysema, but the underlying immune alterations and cellular interactions are incompletely understood. OBJECTIVE: To explore disease-specific pulmonary immune cell alterations and cellular interactions in emphysema. METHODS: We used single-cell mass cytometry to compare the immune compartment in alveolar tissue from 15 patients with severe emphysema and 5 controls...
March 27, 2024: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/38536158/definitions-of-dysbiosis-in-clad-and-high-bacterial-biomass
#7
JOURNAL ARTICLE
John McGinniss
No abstract text is available yet for this article.
March 27, 2024: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/38536110/epidemiology-and-prognostic-significance-of-cough-in-fibrotic-interstitial-lung-disease
#8
JOURNAL ARTICLE
Yet H Khor, Kerri A Johannson, Veronica Marcoux, Jolene H Fisher, Deborah Assayag, Helene Manganas, Nasreen Khalil, Martin Kolb, Christopher J Ryerson
Rationale: Cough is a key symptom in patients with fibrotic interstitial lung disease (ILD). Objective: This study evaluated the prevalence, longitudinal change, associations, and prognostic significance of cough severity in patients with fibrotic ILD. Methods: We included consecutive patients with idiopathic pulmonary fibrosis (IPF) and non-IPF fibrotic ILD who completed the 100mm-Cough Severity Visual Analog Scale (VAS) from the prospective multi-center Canadian Registry for Pulmonary Fibrosis. Baseline cough severity and associations with patient demographics and clinical factors were determined...
March 27, 2024: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/38536108/telehealth-pulmonary-rehabilitation-a-call-for-minimum-standards
#9
JOURNAL ARTICLE
Surya P Bhatt, Richard Casaburi, Christopher L Mosher, Carolyn L Rochester, Chris Garvey
No abstract text is available yet for this article.
March 27, 2024: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/38535489/pragmatic-approach-to-in-situ-simulation-to-identify-latent-safety-threats-before-moving-to-a-newly-built-icu
#10
JOURNAL ARTICLE
Aarti Sarwal, Nicholas A Morris, Janet Crumpler, Terri Gordon, Ian Saunders, James E Johnson, Jeff E Carter
OBJECTIVES: Transitions to new care environments may have unexpected consequences that threaten patient safety. We undertook a quality improvement project using in situ simulation to learn the new patient care environment and expose latent safety threats before transitioning patients to a newly built adult ICU. DESIGN: Descriptive review of a patient safety initiative. SETTING: A newly built 24-bed neurocritical care unit at a tertiary care academic medical center...
March 27, 2024: Critical Care Medicine
https://read.qxmd.com/read/38535090/machine-learning-identifies-higher-survival-profile-in-extracorporeal-cardiopulmonary-resuscitation
#11
JOURNAL ARTICLE
Ruben Crespo-Diaz, Julian Wolfson, Demetris Yannopoulos, Jason A Bartos
OBJECTIVES: Extracorporeal cardiopulmonary resuscitation (ECPR) has been shown to improve neurologically favorable survival in patients with refractory out-of-hospital cardiac arrest (OHCA) caused by shockable rhythms. Further refinement of patient selection is needed to focus this resource-intensive therapy on those patients likely to benefit. This study sought to create a selection model using machine learning (ML) tools for refractory cardiac arrest patients undergoing ECPR. DESIGN: Retrospective cohort study...
March 27, 2024: Critical Care Medicine
https://read.qxmd.com/read/38534520/knee-joint-preservation-in-tactical-athletes-a-comprehensive-approach-based-upon-lesion-location-and-restoration-of-the-osteochondral-unit
#12
REVIEW
Daniel J Cognetti, Mikalyn T Defoor, Tony T Yuan, Andrew J Sheean
The unique physical demands of tactical athletes put immense stress on the knee joint, making these individuals susceptible to injury. In order to ensure operational readiness, management options must restore and preserve the native architecture and minimize downtime, while optimizing functionality. Osteochondral lesions (OCL) of the knee have long been acknowledged as significant sources of knee pain and functional deficits. The management of OCL is predicated on certain injury characteristics, including lesion location and the extent of subchondral disease...
March 1, 2024: Bioengineering
https://read.qxmd.com/read/38534473/a-comparison-of-the-impact-of-pharmacological-treatments-on-cardioversion-rate-control-and-mortality-in-data-driven-atrial-fibrillation-phenotypes-in-critical-care
#13
JOURNAL ARTICLE
Alexander Lacki, Antonio Martinez-Millana
Critical care physicians are commonly faced with patients exhibiting atrial fibrillation (AF), a cardiac arrhythmia with multifaceted origins. Recent investigations shed light on the heterogeneity among AF patients by uncovering unique AF phenotypes, characterized by differing treatment strategies and clinical outcomes. In this retrospective study encompassing 9401 AF patients in an intensive care cohort, we sought to identify differences in average treatment effects (ATEs) across different patient groups. We extract data from the MIMIC-III database, use hierarchical agglomerative clustering to identify patients' phenotypes, and assign them to treatment groups based on their initial drug administration during AF episodes...
February 20, 2024: Bioengineering
https://read.qxmd.com/read/38534255/continuous-and-non-invasive-lactate-monitoring-techniques-in-critical-care-patients
#14
REVIEW
Jose-Luis Lafuente, Samuel González, Clara Aibar, Desirée Rivera, Eva Avilés, Juan-Jose Beunza
Lactate, once merely regarded as an indicator of tissue hypoxia and muscular fatigue, has now gained prominence as a pivotal biomarker across various medical disciplines. Recent research has unveiled its critical role as a high-value prognostic marker in critical care medicine. The current practice of lactate detection involves periodic blood sampling. This approach is invasive and confined to measurements at six-hour intervals, leading to resource expenditure, time consumption, and patient discomfort. This review addresses non-invasive sensors that enable continuous monitoring of lactate in critical care patients...
March 18, 2024: Biosensors
https://read.qxmd.com/read/38533294/a-review-and-discussion-of-full-time-equivalency-and-appropriate-compensation-models-for-an-adult-intensivist-in-the-united-states-across-various-base-specialties
#15
JOURNAL ARTICLE
Michael Nurok, Brigid C Flynn, Marc Pineton de Chambrun, Mina Kazemian, Joel Geiderman, Mark E Nunnally
OBJECTIVES: Physicians with training in anesthesiology, emergency medicine, internal medicine, neurology, and surgery may gain board certification in critical care medicine upon completion of fellowship training. These clinicians often only spend a portion of their work effort in the ICU. Other work efforts that benefit an ICU infrastructure, but do not provide billing opportunities, include education, research, and administrative duties. For employed or contracted physicians, there is no singular definition of what constitutes an intensive care full-time equivalent (FTE)...
April 2024: Critical care explorations
https://read.qxmd.com/read/38532915/commonly-used-diagnostic-label-classes-domain-and-formulation-among-nursing-students-in-ibadan-oyo-state-nigeria
#16
JOURNAL ARTICLE
Iyanuoluwa O Ojo, Elizabeth O Kazeem, Olufemi O Oyediran, Timothy O Oladosu, Adenike A Olaogun, Prisca O Adejumo
BACKGROUND: In order to select nursing actions that will produce the desired results, a nursing diagnosis is crucial. Despite this, it can be challenging for nursing students to recognize and create precise nursing diagnostic labels that are particular to a patient's situation. The study's objectives are to identify the diagnostic labels, classes, and domains that are frequently formulated by nursing students. MATERIALS AND METHODS: A descriptive cross-sectional methodology and a self-developed questionnaire were utilized to gather information from 120 nursing students who were chosen using a simple random sampling technique...
2024: Journal of Education and Health Promotion
https://read.qxmd.com/read/38532636/characterization-of-distinctive-teaching-practices-in-longitudinal-integrated-clerkships-perspectives-from-students-and-faculty
#17
JOURNAL ARTICLE
Jennifer E Adams, Sheilah Jiménez, Vishnu Kulasekaran, Anne Frank, Catherine Ard, Kristina Sandquist, Heather M Cassidy
Phenomenon : Longitudinal integrated clerkships (LICs) are novel curricula that place medical students in long-term learning and coaching relationships with faculty and require adaptation of teaching practices on the behalf of faculty to maximize learning outcomes. An understanding of how teaching in an LIC model differs from teaching trainees in more traditional models is critical to ensuring curricular innovation success through faculty development. Approach : A qualitative approach was used to describe the teaching practices of faculty and learning experiences of student participants in longitudinal integrated clerkships in different clinical and community settings...
March 26, 2024: Teaching and Learning in Medicine
https://read.qxmd.com/read/38532424/efficacy-of-different-doses-of-corticosteroids-in-treating-severe-covid-19-pneumonia
#18
JOURNAL ARTICLE
Ge Zhang, Lin Su, Wenwen Wu, Qing Qiao, Shuncui Gao, Yan Zhang, Yanmei Zhang
BACKGROUND: To investigate the efficacy of different doses of corticosteroids in treating severe coronavirus disease 2019 (COVID-19) pneumonia. METHODS: Between May 01, 2023, and June 20, 2023, 48 patients with severe COVID-19 pneumonia were treated at the Department of Respiratory and Critical Care Medicine of Jinan Fourth People's Hospital. The observation group (21 patients) received standard care and high-dose corticosteroids, (high-dose group). The control group (27 patients) received standard care and low-dose corticosteroids (low-dose group)...
March 26, 2024: Virology Journal
https://read.qxmd.com/read/38531579/skeletal-muscle-relaxants-as-adjunctive-pain-control-following-cardiothoracic-surgery-a-systematic-review-protocol
#19
JOURNAL ARTICLE
Shadman Kabir, Quinn Whaley, Melissa Fernandez, Travis W Murphy
INTRODUCTION: Multimodal pain control following cardiothoracic surgery remains a focus in international guidelines. We hypothesise that non-depolarising skeletal muscle relaxants can prove to be a useful adjunct for this population. METHODS/ANALYSIS: This systematic review will focus on human adult studies of pain control using muscle relaxants within 1 week following cardiac and thoracic surgery available in PubMed, Cochrane Central, Web of Science and EMBASE...
March 25, 2024: BMJ Open
https://read.qxmd.com/read/38531570/precise-infliximab-exposure-and-pharmacodynamic-control-to-achieve-deep-remission-in-paediatric-crohn-s-disease-remodel-cd-study-protocol-for-a-multicentre-open-label-pragmatic-clinical-trial-in-the-usa
#20
JOURNAL ARTICLE
Phillip Paul Minar, Ruben J Colman, Nanhua Zhang, Tomoyuki Mizuno, Alexander A Vinks
INTRODUCTION: The only biologic therapy currently approved to treat moderate to severe Crohn's disease in children (<18 years old) are those that antagonise tumour necrosis factor-alpha (anti-TNF). Therefore, it is critically important to develop novel strategies that maximise treatment effectiveness in this population. There is growing evidence that rates of sustained corticosteroid-free clinical remission, endoscopic healing and drug durability considerably improve when patients receive early anti-TNF dose optimisations guided by reactive or proactive therapeutic drug monitoring and pharmacodynamic monitoring...
March 25, 2024: BMJ Open
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