keyword
https://read.qxmd.com/read/38364198/ambient-temperature-and-risk-of-cardiovascular-and-respiratory-adverse-health-outcomes-a-nationwide-cross-sectional-study-from-spain
#1
JOURNAL ARTICLE
Hicham Achebak, Grégoire Rey, Simon J Lloyd, Marcos Quijal-Zamorano, Raúl Fernando Méndez-Turrubiates, Joan Ballester
AIMS: We assessed the association of temperature and temperature variability with cause-specific emergency hospitalizations and mortality from cardiovascular and respiratory diseases in Spain, as well as the effect modification of this association by individual and contextual factors. METHODS AND RESULTS: We collected data on health (hospital admissions and mortality), weather (temperature and relative humidity), and relevant contextual indicators for 48 Spanish provinces during 2004-2019...
February 13, 2024: European Journal of Preventive Cardiology
https://read.qxmd.com/read/38198221/pcsk9-genetic-variants-and-risk-of-vascular-and-non-vascular-diseases-in-chinese-and-uk-populations
#2
JOURNAL ARTICLE
Michael V Holmes, Christiana Kartsonaki, Ruth Boxall, Kuang Lin, Nicola Reeve, Canqing Yu, Jun Lv, Derrick A Bennett, Michael R Hill, Ling Yang, Yiping Chen, Huaidong Du, Iain Turnbull, Rory Collins, Robert J Clarke, Martin D Tobin, Liming Li, Iona Y Millwood, Zhengming Chen, Robin G Walters
AIM: Lowering low-density lipoprotein cholesterol (LDL-C) through PCSK9 inhibition represents a new therapeutic approach to preventing and treating cardiovascular disease (CVD). Phenome-wide analyses of PCSK9 genetic variants in large biobanks can help to identify unexpected effects of PCSK9 inhibition. METHODS: In the prospective China Kadoorie Biobank, we constructed a genetic score using three variants at the PCSK9 locus associated with directly-measured LDL-C (PCSK9-GS)...
January 10, 2024: European Journal of Preventive Cardiology
https://read.qxmd.com/read/37475566/-expert-consensus-on-the-diagnosis-and-treatment-of-chest-tightness-variant-asthma-in-china
#3
JOURNAL ARTICLE
(no author information available yet)
Chest tightness variant asthma (CTVA) is an atypical asthma, characterized by chest tightness as the only or main clinical manifestation. Due to its lack of typical asthma symptoms and signs, it is prone to misdiagnosis or missed diagnosis. Comprehensive chest tightness symptoms and objective evidence of variable airflow restriction, especially bronchial provocation test, are important criteria of diagnosing CTVA. Patients with CTVA also need to be differentiated from patients with chronic obstructive pulmonary disease, coronary atherosclerotic heart disease, gastroesophageal reflux disease and other diseases...
July 21, 2023: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://read.qxmd.com/read/37018790/rivaroxaban-in-outpatients-with-mild-or-moderate-covid-19-rationale-and-design-of-the-study-care-care-coalition-covid-19-brazil-viii
#4
MULTICENTER STUDY
Gustavo B F Oliveira, Precil Diego M M Neves, Haliton A Oliveira, Daniela Ghidetti Mangas Catarino, Lucas B O Alves, Alexandre B Cavalcanti, Regis G Rosa, Viviane C Veiga, Luciano C P Azevedo, Otávio Berwanger, Renato D Lopes, Álvaro Avezum
BACKGROUND: Previous studies have demonstrated a high risk of arterial and venous thromboembolic events as a consequence of direct viral damage to endothelial cells by SARS-CoV-2 and a procoagulant milieu due to increased biomarkers, such as D-dimer, fibrinogen, and factor VIII. Although randomized controlled trials of antithrombotic therapies have been conducted in hospitalized patients, few have evaluated the role of thromboprophylaxis in an outpatient setting. OBJECTIVE: To assess whether antithrombotic prophylaxis with rivaroxaban reduces the risk of venous or arterial thrombotic events, invasive ventilatory support, and death in COVID-19 outpatients...
March 2023: Arquivos Brasileiros de Cardiologia
https://read.qxmd.com/read/36773703/incident-atrial-fibrillation-in-relation-to-ventilatory-parameters-a-prospective-cohort-study
#5
JOURNAL ARTICLE
Jean Jacques Noubiap, Samuel J Tu, Mehrdad Emami, Melissa E Middeldorp, Adrian D Elliott, Prashanthan Sanders
BACKGROUND: There is a paucity of data on the association between respiratory function and atrial fibrillation (AF). This study aimed to assess the relationship between forced expiratory volume (FEV1), forced vital capacity (FVC), and FEV1/FVC and incident AF. METHODS: We performed an analysis of prospectively collected data from the UK Biobank. We included all participants with available spirometry and excluded those with a prior AF. Incident AF was ascertained through hospitalization and death records, and dose-response associations were assessed using multivariable Cox regression analysis with adjustment for known AF risk factors...
February 9, 2023: Canadian Journal of Cardiology
https://read.qxmd.com/read/36518891/specific-clinical-vignettes-in-high-risk-protected-percutaneous-coronary-intervention
#6
JOURNAL ARTICLE
Vasileios Panoulas, Sian-Tsung Tan, Jonathan Hill, Giuseppe Tarantini
There are several cardiac- and patient-related factors that come into play when considering patients for protected percutaneous coronary intervention (PCI). Cardiac factors include complexity/location of coronary lesions, the degree of left or right ventricular impairment, the presence of valvular lesions, and ventricular arrhythmias. Patient related factors include comorbidities that would render the patient at a higher risk of death should cardiogenic shock ensue during the procedure. Comorbidities include chronic lung disease (chronic obstructive airways disease, asthma, pulmonary fibrosis), renal or liver impairment, other cardiovascular diseases (such as previous cerebrovascular accident or transient ischemic attack, peripheral arterial disease, carotid stenosis), diabetes, frailty and advanced age...
November 2022: European Heart Journal Supplements: Journal of the European Society of Cardiology
https://read.qxmd.com/read/36332908/measurement-of-exhaled-nitric-oxide-fails-to-predict-left-atrial-pressure-assessed-by-e-e-ratio-in-elderly-patients
#7
JOURNAL ARTICLE
Samuel Thomas Jones, Monica Londahl, Anthony Prothero, Richard Hobbs, Ian Pavord, Saul G Myerson, Bernard Prendergast, Sean Coffey
BACKGROUND: During left-sided heart failure, left atrial and pulmonary venous pressure increase, which may lead to pulmonary congestion. Previous cohort studies examining participants with symptomatic heart failure or rheumatic heart disease suggest a relationship between increased left atrial pressure (LAP) and fractional exhaled nitric oxide (FeNO). AIM: In this study, we examined the strength of association between FeNO and echocardiographic assessment of LAP by the E/e' ratio to determine if FeNO could be used to identify those with elevated LAP...
November 4, 2022: BJGP Open
https://read.qxmd.com/read/35772828/impact-of-copd-and-asthma-on-in-hospital-mortality-and-management-of-patients-with-heart-failure-in-england-and-wales-an-observational-analysis
#8
JOURNAL ARTICLE
Claudia Gulea, Rosita Zakeri, Constantinos Kallis, Jennifer K Quint
OBJECTIVE: To evaluate the association between having concomitant chronic obstructive pulmonary disease (COPD) or asthma, and in-patient mortality and post-discharge management among patients hospitalised for acute heart failure (HF). SETTING: Data were obtained from patients enrolled in the National Heart Failure Audit. PARTICIPANTS: 217 329 patients hospitalised for HF in England-Wales between March 2012 and 2018. OUTCOMES: In-hospital mortality, referrals to cardiology follow-up and prescriptions for HF medications were compared between patients with comorbid COPD (COPD-HF) or asthma (asthma-HF) versus HF-alone using mixed-effects logistic regression...
June 30, 2022: BMJ Open
https://read.qxmd.com/read/35653582/impact-of-chronic-coronary-syndromes-on-cardiovascular-hospitalization-and-mortality-the-esc-eorp-cicd-lt-registry
#9
JOURNAL ARTICLE
Mathieu Kerneis, Francesco Cosentino, Roberto Ferrari, Jean-Louis Georges, Elena Kosmachova, Cécile Laroche, Aldo P Maggioni, Harald Rittger, Philippe Gabriel Steg, Justyna Maczynska, Luigi Tavazzi, Marco Valgimigli, Chris P Gale, Michel Komajda
BACKGROUND: In Europe, global data on guideline adherence, geographic variations and determinants of clinical events in Chronic coronary syndrome (CCS) patients remain suboptimal. DESIGN: The European Society of Cardiology (ESC) EORP CICD-LT registry is a prospective European registry, was designed to describe the profile, management and outcomes of patients with CCS across the ESC countries. METHODS: We aimed to investigate clinical events at one-year follow-up from the ESC EORP CICD-LT Registry...
June 2, 2022: European Journal of Preventive Cardiology
https://read.qxmd.com/read/35143875/systematic-screening-for-anxiety-and-depression-in-cardiac-rehabilitation-are-we-there-yet
#10
JOURNAL ARTICLE
Charlotte Helmark, Alex Harrison, Susanne S Pedersen, Patrick Doherty
BACKGROUND: Anxiety and depression are prevalent in 20% of patients with acute coronary syndrome (ACS) and associated with poor outcomes. Guidelines recommend screening for these conditions in cardiac rehabilitation (CR) however, clinical practice is inconsistent. Sparse knowledge exists on determinants for screening. METHODS: This observational study used data from the National Audit of Cardiac Rehabilitation from January 2016-December 2019. A multivariate logistic regression model was performed to analyze patient- and provider level determinants for screening for anxiety and depression among patients with ACS...
April 1, 2022: International Journal of Cardiology
https://read.qxmd.com/read/34650380/certainties-fading-away-%C3%AE-blockers-do-not-worsen-chronic-obstructive-pulmonary-disease
#11
JOURNAL ARTICLE
Paolo Verdecchia, Claudio Cavallini, Stefano Coiro, Clara Riccini, Fabio Angeli
For many years, β-blockers have been considered contraindicated in patients with heart failure (HF) and in those with bronchial asthma or even chronic obstructive pulmonary disease (COPD) although without clear evidence of asthma. Today, despite overwhelming evidence of the usefulness of β-blockers, especially in HF with reduced left ventricular ejection fraction (HFrEF), and in ischaemic heart disease, some reluctance persists in using these drugs when COPD coexists. Such resistance is due to the fear that a possible worsening of bronchospasm induced by β-blockers could induce negative effects greater than the benefits...
October 2021: European Heart Journal Supplements: Journal of the European Society of Cardiology
https://read.qxmd.com/read/34180244/lower-in-hospital-mortality-with-beta-blocker-use-at-admission-in-patients-with-acute-decompensated-heart-failure
#12
MULTICENTER STUDY
Yodo Tamaki, Hidenori Yaku, Takeshi Morimoto, Yasutaka Inuzuka, Neiko Ozasa, Erika Yamamoto, Yusuke Yoshikawa, Makoto Miyake, Hirokazu Kondo, Toshihiro Tamura, Takeshi Kitai, Moritake Iguchi, Kazuya Nagao, Ryusuke Nishikawa, Yuichi Kawase, Takashi Morinaga, Mitsunori Kawato, Mamoru Toyofuku, Yukihito Sato, Koichiro Kuwahara, Yoshihisa Nakagawa, Takao Kato, Takeshi Kimura
Background It remains unclear whether beta-blocker use at hospital admission is associated with better in-hospital outcomes in patients with acute decompensated heart failure. Methods and Results We evaluated the factors independently associated with beta-blocker use at admission, and the effect of beta-blocker use at admission on in-hospital mortality in 3817 patients with acute decompensated heart failure enrolled in the Kyoto Congestive Heart Failure registry. There were 1512 patients (39.7%) receiving, and 2305 patients (60...
July 6, 2021: Journal of the American Heart Association
https://read.qxmd.com/read/33752849/prevalence-and-predictors-of-hypertension-self-care-practice-in-primary-health-care-facilities-in-southern-tunisia
#13
JOURNAL ARTICLE
N Ketata, H Ben Ayed, M Ben Hmida, Z Abdelhedi, M Ben Jemaa, M Trigui, H Maamri, S Yaich, M Kassis, H Feki, J Damak
BACKGROUND: Unmanaged hypertension (HTN) is usually accompanied with complications leading to disability in older adults. It has been demonstrated that self-care practice is essential for blood pressure control and reduction of HTN complications. OBJECTIVE OF THE STUDY: This study aimed to estimate the level of implementation of HTN self-care practice and to identify their associated factors. STUDY DESIGN: It was a cross-sectional study conducted in Sfax, Southern Tunisia in April 2020...
April 2021: Journal de Médecine Vasculaire
https://read.qxmd.com/read/33497697/variation-in-use-and-dosing-escalation-of-renin-angiotensin-system-mineralocorticoid-receptor-antagonist-angiotensin-receptor-neprilysin-inhibitor-and-beta-blocker-therapies-in-heart-failure-and-reduced-ejection-fraction-association-of-comorbidities
#14
MULTICENTER STUDY
Nancy M Albert, Rachel J Tyson, C Larry Hill, Adam D DeVore, John A Spertus, Carol Duffy, Javed Butler, J Herbert Patterson, Adrian F Hernandez, Fredonia B Williams, Laine Thomas, Gregg C Fonarow
BACKGROUND: In patients with heart failure and reduced ejection fraction (HFrEF), angiotensin converting enzyme inhibitors (ACEi), angiotensin II receptor blockers (ARB), or angiotensin receptor neprilysin inhibitor (ARNI), mineralocorticoid receptor antagonists (MRA), and beta-blockers (βB) are underutilized. It is unknown if patients with and without comorbidities have similar ACEi/ARB/ARNI, MRA, and βB prescription patterns. METHODS: Baseline data from the CHAMP-HF (Change the Management of Patients with Heart Failure) registry were categorized by history of atrial fibrillation, asthma/chronic lung disease, obstructive sleep apnea, and depression...
May 2021: American Heart Journal
https://read.qxmd.com/read/33451120/telemedicine-for-pre-employment-medical-examinations-and-follow-up-visits-on-board-ships-a-narrative-review-on-the-feasibility
#15
REVIEW
Getu Gamo Sagaro, Marzio Di Canio, Emanuele Talevi, Francesco Amenta
BACKGROUND: Telemedicine has already been applied to various medical specialties for diagnosis, treatment, and follow-up visits for the general population. Telemedicine has also proven effective by providing advice, diagnosis, and treatment to seafarers during emergency medical events onboard ships. However, it has not yet been applied for pre-employment medical examinations and follow-up visits on board ships. OBJECTIVE: This review aimed to assess the possibility of using telemedicine during periodic visits between one pre-employment medical examination and others on board ships, and to recommend necessary medical examination tests with screening intervals for seafarers...
January 13, 2021: Healthcare (Basel, Switzerland)
https://read.qxmd.com/read/33352093/which-screening-questionnaire-is-best-for-predicting-obstructive-sleep-apnea-in-the-sleep-clinic-population-considering-age-gender-and-comorbidities
#16
JOURNAL ARTICLE
Burcu Oktay Arslan, Zeynep Zeren Uçar Hoşgör, Mehmet Nurullah Orman
OBJECTIVE: The purpose of this study was to evaluate the predictive power of the screening questionnaires including Epworth Sleepiness Scale (ESS), Berlin questionnaire (BQ) and STOP-Bang questionnaire (SBQ) to identify the high-risk patients for OSA in a sleep clinic setting considering age, gender and comorbidities. MATERIAL AND METHODS: 1003 patients who admitted to our sleep center with the preliminary diagnosis of OSA between June 2016-May 2018 were included in the study...
November 2020: Turkish Thoracic Journal
https://read.qxmd.com/read/31496675/extreme-desert-dust-storms-and-copd-morbidity-on-the-island-of-crete
#17
MULTICENTER STUDY
Christina Lorentzou, Giorgos Kouvarakis, Georgios V Kozyrakis, Nikolaos A Kampanis, Irene Trahanatzi, Othon Fraidakis, Nikolaos Tzanakis, Maria Kanakidou, Panagiotis Agouridakis, George Notas
Introduction and objectives: Short-term extreme increases in desert-derived particulate-matter with aerodynamic diameter below 10 μm (PM10 ) may affect emergency department (ED) visits due to COPD exacerbations. Research question: Our aim was to identify the effect of extreme increases in desert-derived PM10 on ED visits for dyspnea and COPD exacerbations and on the related hospital admissions. Methods: We performed a retrospective analysis of dyspnea-related ED visits and hospital admissions in Heraklion, Crete, during four consecutive storms of desert-derived PM10 that happened during March 2018...
2019: International Journal of Chronic Obstructive Pulmonary Disease
https://read.qxmd.com/read/31339629/adherence-to-esc-guideline-recommended-medications-over-a-36-month-follow-up-period-after-hospitalization-for-heart-failure-results-from-the-epical2-cohort-study
#18
MULTICENTER STUDY
Sarah Bitar, Nelly Agrinier, François Alla, Patrick Rossignol, Alexandre Mebazaa, Nathalie Thilly
PURPOSE: The purpose of the study is to describe the trajectories of oral medication prescriptions in patients with heart failure with reduced ejection fraction (HFrEF) over 3 years after discharge from hospitalization for heart failure. We then evaluated the adherence of these prescriptions to the European Society of Cardiology (ESC) guideline-recommended medications and identified patient characteristics associated with nonadherence. METHODS: We used data from the EPICAL2 cohort study...
November 2019: Pharmacoepidemiology and Drug Safety
https://read.qxmd.com/read/29716705/evaluation-for-airway-obstruction-in-adult-patients-with-stable-ischemic-heart-disease
#19
JOURNAL ARTICLE
M Mahendra, Sunil Kumar S, Nagaraj Desai, Jayaraj Bs, Mahesh Pa
BACKGROUND: Ischemic heart disease (IHD) and chronic airway disease (COPD and Asthma) are major epidemics accounting for significant mortality and morbidity. The combination presents many diagnostic challenges. Clinical symptoms and signs frequently overlap. There is a need for airway evaluation in these patients to plan appropriate management. METHODS: Consecutive stable IHD patients attending the cardiology OPD in a tertiary care centre were interviewed for collecting basic demographic information, brief medical, occupational, personal history and risk factors for coronary artery disease and airway disease, modified medical research centre (MMRC) grade for dyspnea, quality of life-St...
March 2018: Indian Heart Journal
https://read.qxmd.com/read/25234932/effect-of-a-care-transition-intervention-by-pharmacists-an-rct
#20
RANDOMIZED CONTROLLED TRIAL
Karen B Farris, Barry L Carter, Yinghui Xu, Jeffrey D Dawson, Constance Shelsky, David B Weetman, Peter J Kaboli, Paul A James, Alan J Christensen, John M Brooks
BACKGROUND: Pharmacists may improve medication-related outcomes during transitions of care. The aim of the Iowa Continuity of Care Study was to determine if a pharmacist case manager (PCM) providing a faxed discharge medication care plan from a tertiary care institution to primary care could improve medication appropriateness and reduce adverse events, rehospitalization and emergency department visits. METHODS: Design. Randomized, controlled trial of 945 participants assigned to enhanced, minimal and usual care groups conducted 2007 to 2012...
September 18, 2014: BMC Health Services Research
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