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https://www.readbyqxmd.com/read/28745946/mentalization-based-treatment-for-borderline-personality-disorder-in-adults-and-adolescents-for-whom-when-and-how
#1
Dine J Feenstra, Patrick Luyten, Dawn L Bales
Borderline personality disorder (BPD) is common in clinical practice. Psychotherapy is the treatment of choice, and mentalization-based treatment (MBT) is one of the empirically supported treatments that are currently available. For adults, two variants of MBT (MBT day hospital [MBT-DH] and MBT intensive outpatient [MBT-IOP]) have been developed and empirically evaluated. The authors review research on the development, efficacy, and implementation of MBT. In conclusion, the authors focus on the implementation of treatment programs for BPD patients...
July 26, 2017: Bulletin of the Menninger Clinic
https://www.readbyqxmd.com/read/28680639/subtypes-of-borderline-personality-disorder-patients-a-cluster-analytic-approach
#2
Maaike L Smits, Dine J Feenstra, Dawn L Bales, Jasmijn de Vos, Zwaan Lucas, Roel Verheul, Patrick Luyten
BACKGROUND: The borderline personality disorder (BPD) population is notably heterogeneous, and this has potentially important implications for intervention. Identifying distinct subtypes of patients may represent a first step in identifying which treatments work best for which individuals. METHODS: A cluster-analysis on dimensional personality disorder (PD) features, as assessed with the SCID-II, was performed on a sample of carefully screened BPD patients (N = 187) referred for mentalization-based treatment...
2017: Borderline Personality Disorder and Emotion Dysregulation
https://www.readbyqxmd.com/read/28675858/mentalization-in-adults-with-attention-deficit-hyperactivity-disorder-comparison-with-controls-and-patients-with-borderline-personality-disorder
#3
Nader Perroud, Deborah Badoud, Sébastien Weibel, Rosetta Nicastro, Roland Hasler, Anne-Lise Küng, Patrick Luyten, Peter Fonagy, Alexandre Dayer, Jean-Michel Aubry, Paco Prada, Martin Debbané
Emotion dysregulation and interpersonal hardships constitute core features of borderline personality disorder (BPD). Research has established the link between these core dysregulations and fluctuations in the capacity to appreciate the mental states that underlie behavior (mentalizing, operationalized as reflective functioning (RF)). As emotion dysregulation and interpersonal hardships also characterize adults with attention deficit hyperactivity disorder (ADHD), this study sought to examine the potential RF impairments affecting this population...
June 30, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28674505/vulnerability-or-sensitivity-to-the-environment-methodological-issues-trends-and-recommendations-in-gene-environment-interactions-research-in-human-behavior
#4
REVIEW
Caroline Leighton, Alberto Botto, Jaime R Silva, Juan Pablo Jiménez, Patrick Luyten
Research on the potential role of gene-environment interactions (GxE) in explaining vulnerability to psychopathology in humans has witnessed a shift from a diathesis-stress perspective to differential susceptibility approaches. This paper critically reviews methodological issues and trends in this body of research. Databases were screened for studies of GxE in the prediction of personality traits, behavior, and mental health disorders in humans published between January 2002 and January 2015. In total, 315 papers were included...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28569524/mentalizing-as-a-mechanism-of-change-in-the-treatment-of-patients-with-borderline-personality-disorder-a-parallel-process-growth-modeling-approach
#5
Celine De Meulemeester, Kristof Vansteelandt, Patrick Luyten, Benedicte Lowyck
Although a number of effective psychotherapeutic treatments have been developed for borderline personality disorder (BPD), little is known about the mechanisms of change explaining the effects of these treatments. There is increasing evidence that impairments in mentalizing or reflective functioning-the capacity to reflect on the internal mental states of the self and others-are a central feature of BPD. To date, no study has directly investigated the core assumption of the mentalization-based approach to BPD, that changes in this capacity are associated with treatment outcome in BPD patients...
June 1, 2017: Personality Disorders
https://www.readbyqxmd.com/read/28472162/the-parental-reflective-functioning-questionnaire-development-and-preliminary-validation
#6
Patrick Luyten, Linda C Mayes, Liesbet Nijssens, Peter Fonagy
This paper reports on three studies on the development and validation of the Parental Reflective Functioning Questionnaire (PRFQ), a brief, multidimensional self-report measure that assesses parental reflective functioning or mentalizing, that is, the capacity to treat the infant as a psychological agent. Study 1 investigated the factor structure, reliability, and relationships of the PRFQ with demographic features, symptomatic distress, attachment dimensions, and emotional availability in a socially diverse sample of 299 mothers of a child aged 0-3...
2017: PloS One
https://www.readbyqxmd.com/read/28447814/undetected-scars-self-criticism-attachment-and-romantic-relationships-among-otherwise-well-functioning-childhood-sexual-abuse-survivors
#7
Dana Lassri, Patrick Luyten, Peter Fonagy, Golan Shahar
BACKGROUND: Studies have consistently demonstrated the negative impact of childhood sexual abuse (CSA) on intimate relationships. The majority of studies have focused on revictimization in at-risk or clinical samples, with very few addressing the impact of CSA on otherwise well-functioning adults and even fewer investigating the psychological mechanisms involved. To fill this gap, this study focuses on the effect of CSA on "normative" (nonviolent) romantic relationships in otherwise well-functioning young women, and the mediating role of personality dimension self-criticism and attachment in this regard...
April 27, 2017: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/28413687/what-we-have-changed-our-minds-about-part-1-borderline-personality-disorder-as-a-limitation-of-resilience
#8
REVIEW
Peter Fonagy, Patrick Luyten, Elizabeth Allison, Chloe Campbell
This paper sets out a recent transition in our thinking in relation to psychopathology associated with personality disorder, in an approach that integrates our thinking about attachment, mentalizing (understanding ourselves and others in terms of intentional mental states) and epistemic trust (openness to the reception of social communication that is personally relevant and of generalizable significance) with recent findings on the structure of both adult and child psychopathology and resilience. In this paper - the first of two parts - we review evidence suggesting that a general psychopathology or p factor underlies vulnerability for psychopathology...
2017: Borderline Personality Disorder and Emotion Dysregulation
https://www.readbyqxmd.com/read/28405338/what-we-have-changed-our-minds-about-part-2-borderline-personality-disorder-epistemic-trust-and-the-developmental-significance-of-social-communication
#9
REVIEW
Peter Fonagy, Patrick Luyten, Elizabeth Allison, Chloe Campbell
In Part 1 of this paper, we discussed emerging evidence suggesting that a general psychopathology or 'p' factor underlying the various forms of psychopathology should be conceptualized in terms of the absence of resilience, that is, the absence of positive reappraisal mechanisms when faced with adversity. These impairments in the capacity for positive reappraisal seem to provide a comprehensive explanation for the association between the p factor and comorbidity, future caseness, and the 'hard-to-reach' character of many patients with severe personality pathology, most notably borderline personality disorder (BPD)...
2017: Borderline Personality Disorder and Emotion Dysregulation
https://www.readbyqxmd.com/read/28263091/attachment-and-reflective-functioning-in-women-with-borderline-personality-disorder
#10
Deborah Badoud, Paco Prada, Rosetta Nicastro, Charlotte Germond, Patrick Luyten, Nader Perroud, Martin Debbané
Insecure attachment and impairments in reflective functioning (RF) are thought to play a critical role in borderline personality disorder (BPD). In particular, the mentalization-based model argues that insecure attachment indirectly accounts for increased BPD features, notably via disruption of RF capacities. Although the mediation relationship between attachment, RF, and BPD is supported by previous evidence, it remains to be directly tested in adults with BPD. In the current study, a sample of 55 female adult BPD patients and 105 female healthy controls completed a battery of self-report measures to investigate the interplay between attachment, RF capacities, and BPD clinical status...
March 6, 2017: Journal of Personality Disorders
https://www.readbyqxmd.com/read/28249080/treating-borderline-personality-disorder-with-psychotherapy-where-do-we-go-from-here
#11
Peter Fonagy, Patrick Luyten, Anthony Bateman
No abstract text is available yet for this article.
April 1, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28168598/brain-activity-underlying-negative-self-and-other-perception-in-adolescents-the-role-of-attachment-derived-self-representations
#12
Martin Debbané, Deborah Badoud, David Sander, Stephan Eliez, Patrick Luyten, Pascal Vrtička
One of teenagers' key developmental tasks is to engage in new and meaningful relationships with peers and adults outside the family context. Attachment-derived expectations about the self and others in terms of internal attachment working models have the potential to shape such social reorientation processes critically and thereby influence adolescents' social-emotional development and social integration. Because the neural underpinnings of this developmental task remain largely unknown, we sought to investigate them by functional magnetic resonance imaging...
June 2017: Cognitive, Affective & Behavioral Neuroscience
https://www.readbyqxmd.com/read/28055257/updating-the-evidence-and-recommendations-for-short-term-psychodynamic-psychotherapy-in-the-treatment-of-major-depressive-disorder-in-adults
#13
Joel M Town, Allan Abbass, Ellen Driessen, Patrick Luyten, Priyanthy Weerasekera
No abstract text is available yet for this article.
January 2017: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
https://www.readbyqxmd.com/read/27687932/bioluminescent-avian-pathogenic-escherichia-coli-for-monitoring-colibacillosis-in-experimentally-infected-chickens
#14
Leon H Oosterik, Huruma N Tuntufye, Jessica Tsonos, Tom Luyten, Sam Noppen, Sandra Liekens, Rob Lavigne, Patrick Butaye, Bruno M Goddeeris
Avian pathogenic Escherichia coli (APEC) are responsible for significant economic losses in the poultry industry. In this study, a model for investigating the pathogenesis of APEC infections was established. APEC strain CH2 (O78) was marked with the luciferase operon (luxCDABE) using a Tn7 transposon and tissues of experimentally infected chickens were analysed for a correlation between the bioluminescent signal and the number of bacteria. Transposition of the lux operon into the chromosome of the APEC isolate did not affect sensitivity to lytic bacteriophages and there was no effect on virulence in an intratracheal infection model in 1-day-old chicks, although results with a subcutaneous infection model were inconclusive...
October 2016: Veterinary Journal
https://www.readbyqxmd.com/read/27597820/attachment-neurobiology-and-mentalizing-along-the-psychosis-continuum
#15
REVIEW
Martin Debbané, George Salaminios, Patrick Luyten, Deborah Badoud, Marco Armando, Alessandra Solida Tozzi, Peter Fonagy, Benjamin K Brent
In this review article, we outline the evidence linking attachment adversity to psychosis, from the premorbid stages of the disorder to its clinical forms. To better understand the neurobiological mechanisms through which insecure attachment may contribute to psychosis, we identify at least five neurobiological pathways linking attachment to risk for developing psychosis. Besides its well documented influence on the hypothalamic-pituary-adrenal (HPA) axis, insecure attachment may also contribute to neurodevelopmental risk through the dopaminergic and oxytonergic systems, as well as bear influence on neuroinflammation and oxidative stress responses...
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/27392018/development-and-validation-of-a-self-report-measure-of-mentalizing-the-reflective-functioning-questionnaire
#16
Peter Fonagy, Patrick Luyten, Alesia Moulton-Perkins, Ya-Wen Lee, Fiona Warren, Susan Howard, Rosanna Ghinai, Pasco Fearon, Benedicte Lowyck
Reflective functioning or mentalizing is the capacity to interpret both the self and others in terms of internal mental states such as feelings, wishes, goals, desires, and attitudes. This paper is part of a series of papers outlining the development and psychometric features of a new self-report measure, the Reflective Functioning Questionnaire (RFQ), designed to provide an easy to administer self-report measure of mentalizing. We describe the development and initial validation of the RFQ in three studies...
2016: PloS One
https://www.readbyqxmd.com/read/27244268/self-critical-perfectionism-dependency-and-symptomatic-distress-in-patients-with-personality-disorder-during-hospitalization-based-psychodynamic-treatment-a-parallel-process-growth-modeling-approach
#17
Benedicte Lowyck, Patrick Luyten, Rudi Vermote, Yannic Verhaest, Kristof Vansteelandt
There is growing evidence for the efficacy and effectiveness of psychotherapy in patients with personality disorder (PD), but very little is known about the factors underlying these effects. Two-polarities models of personality development provide an empirically supported approach to studying therapeutic change. Briefly, these models argue that personality pathology is characterized by an imbalance between development of the capacity for self-definition and for relatedness, with an exaggerated emphasis on issues regarding self-definition and relatedness being expressed in high levels of self-critical perfectionism (SCP) and dependency, respectively...
May 30, 2016: Personality Disorders
https://www.readbyqxmd.com/read/27050327/serum-of-patients-with-active-rheumatoid-arthritis-inhibits-differentiation-of-osteochondrogenic-precursor-cells
#18
Janak L Pathak, Patrick Verschueren, Willem F Lems, Nathalie Bravenboer, Jenneke Klein-Nulend, Astrid D Bakker, Frank P Luyten
Delayed fracture healing is frequently experienced in patients with systemic inflammation such as during rheumatoid arthritis (RA). The reasons for this are diverse, but could also be caused by inflammatory cytokines and/or growth factors in serum from patients with active disease. We hypothesized that serum from patients with active RA contains circulating inflammatory factors that inhibit differentiation of osteochondrogenic precursors. Serum was obtained from 15 patients with active RA (active RA-sera) and from the same patients in clinical remission 1 year later (remission RA-sera; controls)...
May 2016: Connective Tissue Research
https://www.readbyqxmd.com/read/27018923/the-effect-of-childhood-emotional-maltreatment-on-romantic-relationships-in-young-adulthood-a-double-mediation-model-involving-self-criticism-and-attachment
#19
Dana Lassri, Patrick Luyten, Guina Cohen, Golan Shahar
OBJECTIVE: Despite growing recognition of the importance of childhood emotional maltreatment (CEM) on the development of psychopathology, very few studies have addressed its impact on adult romantic relationship functioning, particularly among otherwise relatively well-functioning individuals. In an attempt to further elucidate the mechanism underlying the negative impact of CEM on romantic relationships, we tested an integrative mediational model linking CEM to romantic relationships through the impact of CEM on the development of self-criticism and adult attachment...
July 2016: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/27007498/the-role-of-intergenerational-similarity-and-parenting-in-adolescent-self-criticism-an-actor-partner-interdependence-model
#20
Dries Bleys, Bart Soenens, Liesbet Boone, Stephan Claes, Nicole Vliegen, Patrick Luyten
Research investigating the development of adolescent self-criticism has typically focused on the role of either parental self-criticism or parenting. This study used an actor-partner interdependence model to examine an integrated theoretical model in which achievement-oriented psychological control has an intervening role in the relation between parental and adolescent self-criticism. Additionally, the relative contribution of both parents and the moderating role of adolescent gender were examined. Participants were 284 adolescents (M = 14 years, range = 12-16 years) and their parents (M = 46 years, range = 32-63 years)...
2016: Journal of Adolescence
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