keyword
MENU ▼
Read by QxMD icon Read
search

oleacein

keyword
https://www.readbyqxmd.com/read/28732809/oleacein-may-inhibit-destabilization-of-carotid-plaques-from-hypertensive-patients-impact-on-high-mobility-group-protein-1
#1
Agnieszka Filipek, Monika E Czerwińska, Anna K Kiss, Jerzy A Polański, Marek Naruszewicz
BACKGROUND: In patients with hypertension the haemorrhage into carotid atherosclerotic plaque increases risk of plaque destabilization and rupture. Our previous study showed that oleacein, a secoiridoid present in extra virgin olive oil, enhanced uptake of haemoglobin-haptoglobin complex and change macrophage phenotype from pro-inflammatory M1 to anti-inflammatory M2. PURPOSE: The aim this study was to investigate a potential role of oleacein in attenuation of carotid plaque destabilisation ex vivo...
August 15, 2017: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/28481240/soft-ms-and-computational-mapping-of-oleuropein
#2
REVIEW
Luigi Gentile, Nicola A Uccella, Ganapathy Sivakumar
Olive oil and table olives are rich sources of biophenols, which provides a unique taste, aroma and potential health benefits. Specifically, green olive drupes are enriched with oleuropein, a bioactive biophenol secoiridoid. Olive oil contains hydrolytic derivatives such as hydroxytyrosol, oleacein and elenolate from oleuropein as well as tyrosol and oleocanthal from ligstroside. Biophenol secoiridoids are categorized by the presence of elenoic acid or its derivatives in their molecular structure. Medical studies suggest that olive biophenol secoiridoids could prevent cancer, obesity, osteoporosis, and neurodegeneration...
May 6, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28448631/biofortification-se-does-it-increase-the-content-of-phenolic-compounds-in-virgin-olive-oil-voo
#3
Roberto D'Amato, Primo Proietti, Andrea Onofri, Luca Regni, Sonia Esposto, Maurizio Servili, Daniela Businelli, Roberto Selvaggini
Extra-Virgin Olive Oil (EVOO) is a fundamental component of the Mediterranean diet and it may contain several anti-oxidant substances, such as phenols. Previous research has shown that this food may be enriched in phenols by spraying a sodium-selenate solution (100 mg L-1 Se) onto the crop canopy before flowering. The aim of this research was to evaluate the effect of this Se-fertilization before flowering (cv. Leccino) on the phenolic profile of EVOOs, and test to what extent such effects depend on the weather pattern, as observed in two contrasting experimental seasons (2013 and 2014)...
2017: PloS One
https://www.readbyqxmd.com/read/28395179/antimicrobial-activity-of-olea-europaea-linn%C3%A3-extracts-and-their-applicability-as-natural-food-preservative-agents
#4
REVIEW
J Thielmann, S Kohnen, C Hauser
The antimicrobial activity of phenolic compounds from Olea (O.) europaea Linné (L.) is part of the scientific discussion regarding the use of natural plant extracts as alternative food preservative agents. Although, the basic knowledge on the antimicrobial potential of certain molecules such as oleuropein, hydroxytyrosol or elenolic acid derivatives is given, there is still little information regarding their applicability for food preservation. This might be primarily due to the lack of information regarding the full antimicrobial spectrum of the compounds, their synergisms in natural or artificial combinations and their interaction with food ingredients...
June 19, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28317728/direct-study-of-minor-extra-virgin-olive-oil-components-without-any-sample-modification-1-h-nmr-multisupression-experiment-a-powerful-tool
#5
Ainhoa Ruiz-Aracama, Encarnación Goicoechea, María D Guillén
Proton Nuclear Magnetic Resonance ((1)H NMR) was employed to study monovarietal commercial Spanish extra-virgin olive oils (EVOO) (Arbequina, Arroniz, Cornicabra, Hojiblanca and Picual). Each sample was analyzed by a standard pulse and by an experiment suppressing the main lipid signals, enabling the detection of signals of minor components. The aim was to determine the possibilities of both (1)H NMR approaches to characterize EVOO composition, focusing on acyl groups, squalene, sterols, triterpene acids/esters, fatty alcohols, wax esters and phenols (lignans, tyrosol, hydroxytyrosol, oleocanthal, oleacein, oleokoronal, oleomissional, ligstrodials and oleuropeindials), and to determine hydrolysis and oxidation levels...
August 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28256253/an-integrated-process-for-the-recovery-of-high-added-value-compounds-from-olive-oil-using-solid-support-free-liquid-liquid-extraction-and-chromatography-techniques
#6
Apostolis Angelis, Mahmoud Hamzaoui, Nektarios Aligiannis, Theodora Nikou, Dimitris Michailidis, Panagiotis Gerolimatos, Aikaterini Termentzi, Jane Hubert, Maria Halabalaki, Jean-Hugues Renault, Alexios-Léandros Skaltsounis
An integrated extraction and purification process for the direct recovery of high added value compounds from extra virgin olive oil (EVOO) is proposed by using solid support free liquid-liquid extraction and chromatography techniques. Two different extraction methods were developed on a laboratory-scale Centrifugal Partition Extractor (CPE): a sequential strategy consisting of several "extraction-recovery" cycles and a continuous strategy based on stationary phase co-current elution. In both cases, EVOO was used as mobile phase diluted in food grade n-hexane (feed mobile phase) and the required biphasic system was obtained by adding ethanol and water as polar solvents...
March 31, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/27283606/phenolic-compounds-of-galega-vulgar-and-cobran%C3%A3-osa-olive-oils-along-early-ripening-stages
#7
Fátima Peres, Luisa L Martins, Miguel Mourato, Conceição Vitorino, Paulo Antunes, Suzana Ferreira-Dias
In this study, the lipophilic and hydrophilic phenol composition of virgin olive oils (VOO) obtained from olives from two of the most important Portuguese cultivars ('Galega Vulgar' and 'Cobrançosa'), harvested at different ripening stages and under two irrigation schemes (rain fed and irrigated), was evaluated. Phenolic alcohols (hydroxytyrosol and tyrosol), phenolic acids and derivatives and flavonoids (luteolin and apigenin), as well as tocopherols were quantified. Lipophilic (>300mgkg(-1)) and hydrophilic phenols (>600mgkg(-1)) were present in high contents in both VOO, for early ripening stages...
November 15, 2016: Food Chemistry
https://www.readbyqxmd.com/read/26841137/oil-quality-parameters-and-quantitative-measurement-of-major-secoiridoid-derivatives-in-neb-jmel-olive-oil-from-various-tunisian-origins-using-qnmr
#8
COMPARATIVE STUDY
Amir Ben Mansour, Boutheina Gargouri, Eleni Melliou, Prokopios Magiatis, Mohamed Bouaziz
BACKGROUND: Olive oil contains compounds with interesting biological activities which are influenced by the cultivar, the geographic origin and other factors. The aims of this work were to (1) investigate these factors in Neb Jmel olive oil from various Tunisian origins; (2) determine the influence of geographic conditions on phenolic composition of Neb Jmel olive oil and consequently on the antioxidant compounds; and (3) verify whether oils could be discriminated based on geographical origin...
October 2016: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/26655408/oleacein-enhances-anti-inflammatory-activity-of-human-macrophages-by-increasing-cd163-receptor-expression
#9
Agnieszka Filipek, Monika E Czerwińska, Anna K Kiss, Małgorzata Wrzosek, Marek Naruszewicz
BACKGROUND: Oleacein (dialdehydic form of decarboxymethyl elenolic acid linked to hydroxytyrosol; 3,4-DHPEA-EDA) have been proven to possess antioxidant and anti-inflammatory activity. PURPOSE: In this study, we examined whether oleacein could increase CD163 and IL-10 receptor expression as well as HO-1 intracellular secretion in human macrophages. METHODS: Effect of oleacein (10 and 20 μmol/l) or oleacein together with complexes of haemoglobin (Hb) and haptoglobin 1-1 (Hp11) or haptoglobin 2-2 (Hp22) on expression of IL-10 and CD163 receptor was determined by Flow Cytometry...
December 15, 2015: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/26654091/quantity-and-quality-of-secoiridoids-and-lignans-in-extra-virgin-olive-oils-the-effect-of-two-and-three-way-decanters-on-leccino-and-raggiola-olive-cultivars
#10
Elena Antonini, Alfonso Farina, Emanuele Salvatore Scarpa, Alessandra Frati, Paolino Ninfali
In this investigation, 14 extra virgin olive oils (EVOOs), produced with Leccino and Raggiola olive cultivars, by a new two-way (2W) decanter were compared with 14 EVOOs produced by means of a conventional three-way (3W) decanter. The 2W EVOOs had higher phenol concentrations, as shown by high-performance liquid chromatography/diode array detection (HPLC-DAD) analysis and yielded a higher extraction of the 3,4-DHPEA-EDA (oleacein), 3,4-DHPEA-EA (oleuropein aglycone) and p-HPEA-EDA (oleocanthal). The concentrations of lignans, (+)-pinoresinol and (+)-1-acetoxypinoresinol, detected by HPLC-FLD equipment, were higher in the 2W EVOOs than they were in EVOOs produced using the 3W system...
2016: International Journal of Food Sciences and Nutrition
https://www.readbyqxmd.com/read/26616988/extraction-of-phenolic-compounds-from-virgin-olive-oil-by-deep-eutectic-solvents-dess
#11
Aránzazu García, Elisa Rodríguez-Juan, Guillermo Rodríguez-Gutiérrez, José Julian Rios, Juan Fernández-Bolaños
Deep eutectic solvents (DESs) are "green" solvents, applied in this study for the extraction of phenolic compounds from virgin olive oil (VOO). Different combinations of DES consisting of choline chloride (ChCl) in various mixing ratios with sugars, alcohols, organic acids, and urea, as well as a mixture of three sugars were used. The yields of the DES extractions were compared with those from conventional 80% (v/v) methanol/water. DES showed a good solubility of phenolic compounds with different polarities...
April 15, 2016: Food Chemistry
https://www.readbyqxmd.com/read/26166135/oleocanthal-modulates-estradiol-induced-gene-expression-involving-estrogen-receptor-%C3%AE
#12
Annekathrin Martina Keiler, Sefirin Djiogue, Tino Ehrhardt, Oliver Zierau, Leandros Skaltsounis, Maria Halabalaki, Günter Vollmer
Oleocanthal is a bioactive compound from olive oil. It has attracted considerable attention as it is anti-inflammatory, antiproliferative, and has been shown to possess neuroprotective properties in vitro and in vivo. Delineated from its polyphenolic structure, the aim of this study was to characterize oleocanthal towards estrogenic properties. This might contribute to partly explain the beneficial effects described for the Mediterranean diet. Estrogenic properties of oleocanthal were assessed by different methods: a) stimulation of reporter gene activity in MVLN or RNDA cells either expressing estrogen receptor α or β, b) stimulation of luciferase reporter gene activity in U2OS osteosarcoma cells expressing estrogen receptor α or β, and c) elucidation of the impact on estradiol-induced gene expression in U2OS cells transduced with both estrogen receptors...
September 2015: Planta Medica
https://www.readbyqxmd.com/read/25693970/quantitative-determination-of-secoiridoids-and-phenylpropanoids-in-different-extracts-of-ligustrum-vulgare-l-leaves-by-a-validated-hptlc-photodensitometry-method
#13
Monika E Czerwińska, Marlena Ziarek, Agnieszka Bazylko, Ewa Osińska, Anna K Kiss
INTRODUCTION: The genus Ligustrum (Oleaceae) is distributed in Europe and Asia (south China and Korea), where it is used to prevent hypertension, sore throats, inflammation and diabetes. The main groups of compounds in extracts of Ligustrum vulgare are biologically active secoiridoids and phenylpropanoids. OBJECTIVES: The aim of the study was primarily the development and validation of a HPTLC-photodensitometry method for separation and determination of secoiridoids (oleacein, oleuropein) and phenylpropanoids (echinacoside) in different extracts prepared from leaves of L...
July 2015: Phytochemical Analysis: PCA
https://www.readbyqxmd.com/read/25312731/oleacein-translation-from-mediterranean-diet-to-potential-antiatherosclerotic-drug
#14
REVIEW
Marek Naruszewicz, Monika E Czerwińska, Anna K Kiss
Epidemiological studies suggest that the cardioprotective properties of olive oil, particularly extra-virgin type, result from a positive influence of its components, such as phenolic compounds, on the cardiovascular system. One of the most abundant phenolic compounds of extra virgin olive oil is the dialdehydic form of elenolic acid conjugated with 3, 4-(dihydroxyphenyl)ethanol (3, 4- DHPEA-EDA), also known as oleacein. Due to its abundance in olive oil, it may play a special role in decreasing the progression of atherosclerosis...
2015: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/25236241/quantitative-analysis-of-pungent-and-anti-inflammatory-phenolic-compounds-in-olive-oil-by-capillary-electrophoresis
#15
Isabella Vulcano, Maria Halabalaki, Leandros Skaltsounis, Markus Ganzera
The first CE procedure for the quantitative determination of pharmacologically relevant secoiridoids in olive oil, oleocanthal and oleacein, is described. Together with their precursors tyrosol and hydroxytyrosol they could be baseline separated in less than 15min using a borax buffer with pH 9.5, at 25kV and 30°C. Method validation confirmed that the procedure is selective, accurate (recovery rates from 94.0 to 104.6%), reproducible (σmax⩽6.8%) and precise (inter-day precision⩽6.4%), and that the compounds do not degrade quickly if non-aqueous acetonitrile is used as solvent...
February 15, 2015: Food Chemistry
https://www.readbyqxmd.com/read/24657078/components-of-a-standardised-olive-leaf-dry-extract-ph-eur-promote-hypothiocyanite-production-by-lactoperoxidase
#16
Jörg Flemmig, Dorothea Rusch, Monika Ewa Czerwińska, Hans-Wilhelm Rauwald, Jürgen Arnhold
We investigated in vitro the ability of a standardised olive leaf dry extract (Ph. Eur.) (OLE) as well as of its single components to circumvent the hydrogen peroxide-induced inhibition of the hypothiocyanite-producing activity of lactoperoxidase (LPO). The rate of hypothiocyanite (⁻OSCN) formation by LPO was quantified by spectrophotometric detection of the oxidation of 5-thio-2-nitrobenzoic acid (TNB). By using excess hydrogen peroxide, we forced the accumulation of inactive enzymatic intermediates which are unable to promote the two-electronic oxidation of thiocyanate...
May 1, 2014: Archives of Biochemistry and Biophysics
https://www.readbyqxmd.com/read/24568174/one-step-semisynthesis-of-oleacein-and-the-determination-as-a-5-lipoxygenase-inhibitor
#17
Konstantina Vougogiannopoulou, Christelle Lemus, Maria Halabalaki, Carlo Pergola, Oliver Werz, Amos B Smith, Sylvie Michel, Leandros Skaltsounis, Brigitte Deguin
The dialdehydes oleacein (2) and oleocanthal (4) are closely related to oleuropein (1) and ligstroside (3), the two latter compounds being abundant iridoids of Olea europaea. By exploiting oleuropein isolated from the plant leaf extract, an efficient procedure has been developed for a one-step semisynthesis of oleacein under Krapcho decarbomethoxylation conditions. Highlighted is the fact that 5-lipoxygenase is a direct target for oleacein with an inhibitory potential (IC50: 2 μM) more potent than oleocanthal (4) and oleuropein (1)...
March 28, 2014: Journal of Natural Products
https://www.readbyqxmd.com/read/24491692/inhibition-of-human-neutrophils-nep-activity-cd11b-cd18-expression-and-elastase-release-by-3-4-dihydroxyphenylethanol-elenolic-acid-dialdehyde-oleacein
#18
Monika E Czerwińska, Anna K Kiss, Marek Naruszewicz
Polyphenols, such as oleacein (3,4-DHPEA-EDA; 3,4-dihydroxyphenylethanol-elenolic acid dialdehyde), are believed to play a role in the prevention of cardiovascular diseases. Due to an increase of neutrophil mediators in acute myocardial infarction the aim of this study was to establish the effect of oleacein on neutral endopeptidase (NEP) activity and other functions of human neutrophils, such as elastase, MMP-9 and IL-8 production. The effect on CD62L and CD11b/CD18 expression on neutrophils was also determined...
June 15, 2014: Food Chemistry
https://www.readbyqxmd.com/read/24384036/quantitative-measurement-of-major-secoiridoid-derivatives-in-olive-oil-using-qnmr-proof-of-the-artificial-formation-of-aldehydic-oleuropein-and-ligstroside-aglycon-isomers
#19
Evangelia Karkoula, Angeliki Skantzari, Eleni Melliou, Prokopios Magiatis
A previously developed method for measurement of oleocanthal and oleacein in olive oil by quantitative (1)H NMR was expanded to include the measurement of the monoaldehydic forms of oleuropein and ligstroside aglycons. The method was validated and applied to the study of 340 monovarietal Greek and Californian olive oils from 23 varieties and for a 3-year period. A wide variation concerning the concentrations of all four secoiridoids was recorded. The concentration of each one ranged from nondetectable to 711 mg/kg and the sum of the four major secoiridoids (named as D3) ranged from nondetectable to 1534 mg/kg...
January 22, 2014: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/23809250/oleuropein-and-oleacein-may-restore-biological-functions-of-endothelial-progenitor-cells-impaired-by-angiotensin-ii-via-activation-of-nrf2-heme-oxygenase-1-pathway
#20
Andrzej Parzonko, Monika E Czerwińska, Anna K Kiss, Marek Naruszewicz
Endothelial progenitor cells (EPCs) are responsible for neovascularization of ischaemic tissue and may participate in re-endothelization of an injured arterial wall. There is evidence that angiotensin II, by an increase of gp91phox expression and induction of ROS generation, accelerates cell senescence and impairs functions of EPCs. Oleacein is a main phenolic compound from olive oil, whereas oleuropein is present in olive leaves. Both compounds possess antioxidative, hypotensive and anti-inflammatory properties and show beneficial activity on the cardiovascular system...
September 15, 2013: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
keyword
keyword
71807
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"