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Claudio Gambardella, Ernesto Tartaglia, Anna Nunziata, Graziella Izzo, Giuseppe Siciliano, Fabio Cavallo, Claudio Mauriello, Salvatore Napolitano, Guglielmo Thomas, Domenico Testa, Gianluca Rossetti, Alessandro Sanguinetti, Nicola Avenia, Giovanni Conzo
BACKGROUND: Lymph nodal involvement is very common in differentiated thyroid cancer, and in addition, cervical lymph node micrometastases are observed in up to 80 % of papillary thyroid cancers. During the last decades, the role of routine central lymph node dissection (RCLD) in the treatment of papillary thyroid cancer (PTC) has been an object of research, and it is now still controversial. Nevertheless, many scientific societies and referral authors have definitely stated that even if in expert hands, RCLD is not associated to higher morbidity; it should be indicated only in selected cases...
2016: World Journal of Surgical Oncology
A Solazzo, V D'Auria, L G Moccia, A Vatrella, M Bocchino, G Rea
Two mediastinal masses were incidentally detected at high resolution computed tomography (HRCT) of a 72 year-old male patient, former smoker, affected by chronic obstructive pulmonary disease with worsening dyspnea and 2-year medical history of polycythemia secondary to hypoxia. Integration with a multidetector computed tomography (MDCT) scan after administration of intravenous injection contrast medium showed slightly inhomogeneous increase of enhancement of masses, suggesting in the first case potential malignancy...
May 2016: Translational Medicine @ UniSa
Raffaele Tinelli, Ettore Cicinelli, Andrea Tinelli, Stefano Bettocchi, Stefano Angioni, Pietro Litta
OBJECTIVE: The aim of this study was to retrospectively compare in a series of 110 patients with early-stage endometrial cancer recurrence rate and surgical outcomes after total laparoscopic (LPS) hysterectomy with lymphadenectomy performed with or without uterine manipulator. STUDY DESIGN: 110 patients with clinical stage I endometrial cancer were enrolled in a retrospective study and underwent surgical staging comprised of LPS hysterectomy, bilateral salpingo-oophorectomy, and in all cases we performed systematic bilateral pelvic lymphadenectomy with uterine manipulator (Group 1, 55 patients) or without (Group 2, 55 patients)...
June 2016: Surgical Oncology
Ran Xu, Dengfeng Li, Jiao Peng, Jing Fang, Liping Zhang, Lianguo Liu
Collagen is the main structural protein of various connective tissues in animals and naturally plays an important role within the body. It is increasingly used within certain areas, such as medicine, citology and cosmetology. The soft-shelled turtle (Pelodiscus sinensis) is a commercially important aquatic species rich in collagen. In this study, a novel collagen gene fragment of 756 bp, which encodes 252 deduced amino acid residues, including 25 conserved Gly-X-Y motifs, was cloned from a soft-shelled turtle...
June 2016: World Journal of Microbiology & Biotechnology
Claudio Ricci, Riccardo Casadei, Giovanni Taffurelli, Elia Zani, Nico Pagano, Carlo Alberto Pacilio, Carlo Ingaldi, Selene Bogoni, Donatella Santini, Marina Migliori, Mariacristina Di Marco, Carla Serra, Lucia Calculli, Roberto De Giorgio, Francesco Minni
OBJECTIVES: This study aimed to evaluate the accuracy of the risk factors proposed by Fukuoka guidelines in detecting malignancy of branch-duct intraductal papillary mucinous neoplasms. METHOD: Diagnostic meta-analysis of cohort studies. A systematic literature search was conducted using MEDLINE, the Cochrane Library, Scopus, and the ISI-Web of Science databases to identify all studies published up to 2014. RESULTS: Twenty-five studies (2025 patients) were suitable for the meta-analysis...
October 2016: Pancreas
Víctor Manuel Vargas-Hernández, Víctor Manuel Vargas-Aguilar, José María Tovar-Rodríguez
Cervico-uterine cancer screening with cytology decrease incidence by more than 50%. The cause of this cancer is the human papilloma virus high risk, and requires a sensitive test to provide sufficient sensitivity and specificity for early detection and greater interval period when the results are negative. The test of the human papilloma virus high risk, is effective and safe because of its excellent sensitivity, negative predictive value and optimal reproducibility, especially when combined with liquid-based cytology or biomarkers with viral load, with higher sensitivity and specificity, by reducing false positives for the detection of cervical intraepithelial neoplasia grade 2 or greater injury, with excellent clinical benefits to cervical cancer screening and related infection of human papilloma virus diseases, is currently the best test for early detection infection of human papillomavirus and the risk of carcinogenesis...
September 2015: Cirugia y Cirujanos
F De Corti, G Cecchetto, R Vendraminelli, G Mognato
INTRODUCTION: In pediatric population Fine-Needle Aspiration Citology (FNAC) is slowly gaining acceptance in clinical management of Superficial Lymphadenopathy (SL). Our experience adds some data about the usefulness of this technique in diagnosing the cause of a SL and therefore guiding further treatment. PATIENTS AND METHODS: 238 FNAC were performed in 217 patients with SL, observed at our Institution from 2002 to 2006. The neck was the most frequent localization...
March 2014: La Pediatria Medica e Chirurgica: Medical and Surgical Pediatrics
Giorgio Grani, Anna Calvanese, Giovanni Carbotta, Mimma D'Alessandri, Angela Nesca, Marta Bianchini, Marianna Del Sordo, Martina Vitale, Angela Fumarola
BACKGROUND: Whether the risk of cancer is increased in patients with chronic autoimmune thyroiditis is a controversial issue. METHODS: Between May 2005 and October 2012, 3777 fine-needle aspiration cytologies (FNACs) were performed on 2562 patients. Serum FT4, thyroid-stimulating hormone (TSH), anti-thyroglobulin antibody (TgAb), and anti-thyroperoxidase antibody (TPOAb) were determined. RESULTS: Patients with suspicious cytology were younger and presented smaller maximum lesion diameter...
February 2015: Head & Neck
R Manrique Lipa, E González Sánchez, M Asencio Duran, P Gonzalez-Peramato, A Fonseca Santodomingo
PURPOSE: To report a case of iris abscess due to bacterial endocarditis. CASE REPORT: A 46-year-old male under diagnosis of promielocitic leukemia and endocarditis presented with decreased vision in left eye (OS). Ophthalmic exploration revealed iris abscess and hypopyon with fibrinous exudate in iris of the left eye and tyndall +1 in right eye (OD). Blood culture and anterior chamber paracentesis was positive for methicillin-sensitive Staphylococcus aureus and negative for blastic cells in citology...
April 2014: Archivos de la Sociedad Española de Oftalmología
Nicola Quaranta, Claudia Milella, Lucia Iannuzzi, Matteo Gelardi
OBJECTIVE: The aim of the present study was to evaluate the role of the different forms of chronic rhinitis in the pathogenesis of otitis media with effusion in children affected by obstructive adenoid hypertrophy. METHODS: 81 patients, aged between 4 and 15 years (mean age of 6.9 years), affected by obstructive adenoid hypertrophy were evaluated. All patients underwent accurate history taking, physical examination with endoscopy of the nasopharynx, skin prick test, nasal cytology and hearing evaluation...
December 2013: International Journal of Pediatric Otorhinolaryngology
A Vidal-Casariego, L López-González, A Jiménez-Pérez, M D Ballesteros-Pomar, G Kyriakos, A Urioste-Fondo, R Álvarez-San Martín, I Cano-Rodríguez, J M Jiménez-García de la Marina
OBJECTIVE: Stiffness has been associated to malignancy in prostate and breast, as well as thyroid. Ultrasound elastography objectively measures tissue elasticity, and previous studies have described it as a high sensitivity and specificity technique for the detection of malignant thyroid nodules in high-risk populations. The aim was to assess the accuracy of elastography in a population with low risk of malignancy. DESIGN AND PATIENTS: 128 consecutive patients with nodular goiter were recruited...
November 2012: Experimental and Clinical Endocrinology & Diabetes
Merielen Garcia Nascimento e Pontes, Sara Martorelli da Silveira, José Carlos de Souza Trindade Filho, Silvia Regina Rogatto, João Lauro Viana de Camargo
OBJECTIVE: To understand developmental characteristics of urinary bladder carcinomas (UBC) by evaluating genomic alterations and p53 protein expression in primary tumors, their recurrences, and in the morphologically normal urothelium of UBC patients. METHODS: Tumors and their respective recurrences, six low-grade and five high-grade cases, provided 19 samples that were submitted to laser microdissection capture followed by high resolution comparative genomic hybridization (HR-CGH)...
August 2013: Urologic Oncology
Ana Luiza Silva Rio, Rosa Paula Mello Biscolla, Danielle Macellaro Andreoni, Cléber Pinto Camacho, Cláudia Cristina Doimo Nakabashi, Maria da Conceição de Oliveira Carneiro Mamone, Elza Setsuku Ikejiri, Luiza K Matsumura, Jairo Tabacow Hidal, Rui Monteiro de Barros Maciel, Reinaldo Perrone Furlanetto
OBJECTIVE: To evaluate the risk of malignancy in thyroid nodules through clinical, laboratory, ultrasonographic and cytological aspects. PATIENTS AND METHODS: 741 nodules of 407 patients. RESULTS: The cytology was benign (60,5%), indeterminate (23,3%), malignant (8,3%) or nondiagnostic (7,6%). The prevalence of cancer in indeterminate citology was 18,5% (16% in follicular lesions, 44% in suspicious). The diagnosis of malignancy was 17,2% (n = 70)...
February 2011: Arquivos Brasileiros de Endocrinologia e Metabologia
Carolina Balduzzi, Martin Yantorno, Iván Mosca, Mirta Apraiz, María J Velázquez, María del Carmen Puente, Valeria Moragrega, Regina Ligorría, Anabel Ottino, Rodrigo Belloni, Rodolfo Barbero, Alejandro Jmelniztky, Néstor Chopita
Primary hepatic lymphoma (PHL) is confined to the liver with no evidence of extrahepatic lymphomatosis. Histopathologically, the PHL belongs to the group of non-Hodgkin's lymphomas and the most common subtype is the diffise large B-cell lymphoma. We present a 72-year-old woman, with no relevant antecedents and the following symptoms: early satiety, abdominal discomfort and rapid weight loss. Liver function tests are normal, erythrocyte sedimentation rate is accelerated and LDH progressively increases during the hospitalization...
December 2010: Acta Gastroenterologica Latinoamericana
A Volpi, G D'Elia, O C Pannarale, F Di Gennaro, P Guida, E Martinelli, A Kavvadias, G Balducci, P Ialongo, A Panebianco, M De Luca, G Fabiano, N Palasciano
Recent studies show that interaction between LN (heterotrimeric protein formed by a3/b3/g2 chains) and cancer cells plays an important role in tumor invasion, also in colorectal cancer. The overall survival was significantly worse in patients with free peritoneal cancer cells(FPTCs): detection of FPTCs after curative surgery is a challenge, because could improve staging and prognosis. Peritoneal citology is the current standard procedure with very low sensivity. We aimed to study the expression of LN5 in the peritoneal lavage of colorectal cancer pts and in controls with semiquantitative reverse trancriptase-polymerase chain reaction (RT-PCR)...
January 2011: Il Giornale di Chirurgia
Marco Antônio Condé de Oliveira, Sérgio Setsuo Maeda, Patrícia Dreyer, Alberto Lobo, Victor Piana de Andrade, Ana O Hoff, Rosa Paula Mello Biscolla, Paola Smanio, Cynthia M A Brandão, José G Vieira
OBJECTIVE: In patients with primary hyperparathyroidism, candidates for surgical intervention, the parathyroid pre-operative localization is of fundamental importance in planning the appropriate surgical approach. MATERIALS AND METHODS: The additional acquisition of SPECT and Technetium-99m images, during parathyroid scintigraphy with Sestamibi, is not common practice. Usually, only planar image acquisition, 15 minutes prior and 2 hours after radiopharmaceutical administration, is performed...
June 2010: Arquivos Brasileiros de Endocrinologia e Metabologia
I Batashki, D Markova, N Milchev
The aim of the study was to evaluate the frequency of cytolitic vaginosis amongst women with symptoms that mimic vulvovaginal candidiasis. We include 1152 patients, which are microbiologically and citologically tested. We found in 3.9% cytolytic vaginosis. The clinical presentation is suggestive of vulvovaginal candidiasis. The differentiation of these two conditions is essential for appropriate treatment and resolution of chronic vaginal subjective complaints.
2009: Akusherstvo i Ginekologii︠a︡
L Charúa-Guindic, E A Esquivel-Ocampo, J A Villanueva-Herrero, B Jiménez-Bobadilla, S B Muñoz-Cortés, M Leal-Tamez, O Avendaño-Espinosa
BACKGROUND: An association between human papilloma virus (HPV) infection and progression to anal intraepithelial neoplasia (AIN) and epidermoid cancer has been established. OBJECTIVE: To know the prevalence of low and high grade AIN, as well as HPV infection in an anoreceptive patients group, infected or not, by human immunodeficiency virus (HIV). MATERIAL AND METHODS: All patients with anoreceptive sexual relations were considered in this study...
2009: Revista de Gastroenterología de México
Renata Pittella Cançado, Liliane Soares Yurgel, Manoel Sant'anna Filho
An evaluation of the cellular alterations in the smoker's oral mucosal cells was performed. Exfoliative Citology technique were applied and the cytologic smears stained with silver for quantitative analyses of Argyrophilic nucleolar organizer regions. (AgNORs). Cytologic smears were collected from two anatomic sites, mouth floor and tongue border with the purpose of relating the frequency of smoking with the quantitative analyses of the AgNORs. This study showed that the average number of AgNORs/nucleus is related with the number of cigarettes per day in the mouth floor of smoker's...
2004: Tobacco Induced Diseases
L Giovanella
Thyroid nodules are common and are frequently benign. The prevalence of thyroid nodules ranges from 3-7% (palpation) to 50% (ultrasonography). Thyroid cancer occurs in 5-10% of nodules. Thyroid ultrasonography (US) is not a screening test but all patients with palpable thyroid nodule should undergo US examination. US-guided fine-needle aspiration citology (FNC) is recommendend for nodules with suspicious features at US examination or when clinical risk factors occur. A radioisotope scan is useful if the TSH is low or suppressed to detect (benign) functioning nodules...
January 21, 2009: Praxis
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