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Catherine L Blaser, Christine Murto
From the Field is a semi-regular column that explores what it means to be a local health professional on the front lines of an emergency. National Association of County and City Health Officials (NACCHO) members share their stories of preparing for and responding to disasters, epidemics, and other major health issues. Through exploring the analysis of the challenges faced and the solutions developed, readers can learn how these public health champions keep their communities safe even in extreme situations. Readers may submit topics of interest to the column's editor, Meghan McGinty, PhD, MPH, MBA, at mmcginty@naccho...
October 12, 2017: Health Security
Niko C Bock, Mitra Saffar, Helge Hudel, Marjut Evälahti, Kaisa Heikinheimo, David P Rice, Sabine Ruf
Aim: To investigate the long-term (≥15 years) post-treatment (Tx) occlusal changes and outcome quality after Class II:1 Tx. Subjects and Methods: Herbst-MBA Tx had been performed at age 12.8 ± 2.7 years in 119 patients. A recall was conducted and study models from before and after active Tx, after retention as well as after recall were evaluated using standard occlusal variables and the PAR index. These data were compared to 31 untreated Class I controls. Results: 52 out of 119 patients could be located and participated at 33...
July 11, 2017: European Journal of Orthodontics
Sarah Gwyn, Gretchen Cooley, Brook Goodhew, Stephan Kohloff, Natalie Banniettis, Ryan Wiegand, Diana L Martin
Antibody responses to Chlamydia trachomatis (CT) antigens may be useful tools for surveillance of trachoma by estimating cumulative prevalence of infection within a population. Data were compared from three different platforms-multiplex bead array (MBA), enzyme-linked immunosorbent assay (ELISA), and lateral flow assay (LFA)-measuring antibody responses against the CT antigen protein plasmid gene product 3 (Pgp3). Sensitivity was defined as the proportion of specimens testing antibody positive from a set of dried blood spots from Tanzanian 1-9-year olds who were positive for CT nucleic acid of all nucleic acid amplification test (NAAT)-positive individuals (N = 103)...
September 25, 2017: American Journal of Tropical Medicine and Hygiene
Minna Moreira Dias Romano, Marina Branco, Henrique Turin Moreira, André Schmidt, Joseph Kisslo, Benedito Carlos Maciel
BACKGROUND: Use of echocardiography (echo) has exponentially increased in recent decades. Concerned about this scientific society developed appropriate use criteria (AUC). Clinical management still suffers geographical variations, and no objective data are available about echo AUC in developing countries. We aimed to evaluate (1) the appropriateness of referrals and (2) their relation to changes in clinical decision management. METHODS: Prospective analysis of referrals from January to December 2014...
October 10, 2017: Echocardiography
Tao Zhou, Yan Wang, Sheng Huang, Youcai Zhao
Nearly 1.3 billion tons of food are discarded annually in the production process. In this study, a novel slow-release nitrogen fertilizer with water absorbency was developed using leftover rice and crosslinking methods. Urea was incorporated as the nitrogen source in a leftover rice-g-poly(acrylic acid)/montmorillonite (LR-g-PAA/MMT) network, and then the leftover rice-g-poly(acrylic acid)/montmorillonite/Urea (LR-g-PAA/MMT/Urea) retained in the soil, and used as the loss control agent for water and nutrients...
October 4, 2017: Science of the Total Environment
Selidji T Agnandji, José F Fernandes, Emmanuel B Bache, Régis M Obiang Mba, Jessica S Brosnahan, Lumeka Kabwende, Paul Pitzinger, Pieter Staarink, Marguerite Massinga-Loembe, Verena Krähling, Nadine Biedenkopf, Sarah Katharina Fehling, Thomas Strecker, David J Clark, Henry M Staines, Jay W Hooper, Peter Silvera, Vasee Moorthy, Marie-Paule Kieny, Akim A Adegnika, Martin P Grobusch, Stephan Becker, Michael Ramharter, Benjamin Mordmüller, Bertrand Lell, Sanjeev Krishna, Peter G Kremsner
BACKGROUND: The rVSVΔG-ZEBOV-GP vaccine prevented Ebola virus disease when used at 2 × 107 plaque-forming units (PFU) in a trial in Guinea. This study provides further safety and immunogenicity data. METHODS AND FINDINGS: A randomised, open-label phase I trial in Lambaréné, Gabon, studied 5 single intramuscular vaccine doses of 3 × 103, 3 × 104, 3 × 105, 3 × 106, or 2 × 107 PFU in 115 adults and a dose of 2 × 107 PFU in 20 adolescents and 20 children. The primary objective was safety and tolerability 28 days post-injection...
October 2017: PLoS Medicine
Uchenna Ekwochi, Isaac Nwabueze Asinobi, Donatus Chidiebere Ignatius Osuorah, Ikenna Kingsley Ndu, Christain Ifediora, Ogechukwu F Amadi, Gabriel Sunday Mba
Congenital abnormalities are important causes of morbidity and mortality in children and significantly add to the burdens on healthcare in developing countries. Unfortunately, there remains a paucity of information on congenital birth defects in most developing countries. This is a 4-year prospective study that assessed the patterns and predictors of congenital anomalies among newborns at the Enugu State University Teaching Hospital, Nigeria. In total, 5830 deliveries were recorded, of which 38 had congenital anomalies, giving an incidence rate of 6...
September 13, 2017: Journal of Tropical Pediatrics
J R McConnell, M A Baird
INTRODUCTION: Public expectations regarding access to the emergency department (ED) challenges providers and policy makers with finite resources being stretched beyond capacity. To enable education of a greater numbers of doctors the format of the medical internship in Australia has changed and assumes that sufficient supervision is provided to interns to enable image interpretation skills development. Furthermore this assumes that appropriate foundational skills are established during undergraduate education...
November 2017: Radiography
Yan Zhang, Jian Xiao, Yimin Sun, Lu Wang, Xulin Dong, Jinghua Ren, Wenshan He, Fei Xiao
The rapidly growing demand for in situ real-time monitoring of chemical information in vitro and in vivo has attracted tremendous research efforts into the design and construction of high-performance biosensor devices. Herein, we develop a new type of flexible nanohybrid microelectrode based on carbon fiber wrapped by gold nanoparticles decorated nitrogen-doped carbon nanotube arrays, and explore its practical application in in situ electrochemical detection of cancer biomarker H2O2 secreted from live cancer cells...
September 22, 2017: Biosensors & Bioelectronics
Loressa Cole, Jeffrey N Doucette
In October 2016, the American Nurses Credentialing Center (ANCC) announced the appointment of Loressa Cole, DNP, MBA, RN, FACHE, NEA-BC, as its new executive director and executive vice president and Jeffrey Doucette, DNP, RN, CENP, FACHE, NEA-BC, LNHA, as its new vice president of the Magnet Recognition® and Pathway to Excellence® Programs. In this Magnet® Perspectives column, we learn more about these 2 dynamic leaders at the helm of ANCC.
October 2017: Journal of Nursing Administration
Yasutaka Kitahama, Hiroaki Hayashi, Tamitake Itoh, Yukihiro Ozaki
Surface-enhanced hyper-Raman scattering (SEHRS) spectra were obtained at desired positions on yeast by focusing a continuous wave near-infrared laser beam while silver nanoparticles (AgNPs) were simultaneously optically trapped. However, the optically trapped colloidal AgNP suspension bubbled up at the focusing point, preventing spectral measurement. In the case of optically trapped AgNPs functionalized with 4-mercaptobenzoic acid (p-MBA), surface-enhanced hyper-Rayleigh scattering was considerably strong, indicating the suppression of the photothermal conversion to form the bubble...
September 27, 2017: Analyst
Seyedeh Mahnaz Modarresi-Saryazdi, Vahid Haddadi-Asl, Mehdi Salami-Kalajahi
N,N'-methylenebis(acrylamide) (MBA)-crosslinked poly(acrylic acid) (PAA) particles with low degree of cross-linking were synthesized using distillation precipitation polymerization. Size and size distribution of particles were obtained using dynamic light scattering and field emission scanning electron microscopy( and results showed that microspheres had a narrow size dispersity. Proton nuclear magnetic resonance results indicated that amount of cross-linker in structure of particles is a little more than the molar percentage of feeded MBA because of greater activity ratio of MBA than AA...
September 18, 2017: Journal of Biomedical Materials Research. Part A
Stephen Hull, Seán Kelley, Janice L Clarke
Sexually Transmitted Infections: Compelling Case for an Improved Screening Strategy Stephen Hull, MHS, Seán Kelley, MD, MSc, and Janice L. Clarke, RN, BBA Editorial: Sexually Transmitted Infections-A Fixable Problem: David B. Nash, MD, MBA   S-3 Introduction   S-3 Rising Prevalence of Sexually Transmitted Diseases (STIs)   S-4 Current Screening Rates for Chlamydia and Gonorrhea   S-4 The Human Toll and Economic Burden of STI-Related Illness   S-5 Current Screening Guidelines for Chlamydia and Gonorrhea   S-5 Factors Contributing to Inadequate Screening, Diagnosis, and Treatment for STIs   S-6 Methods Used to Improve Screening Rates   S-7 Benefits of Opt-Out Screening Strategies for STIs   S-8 Cost-Effectiveness of Screening for STIs   S-8 Discussion   S-9 Conclusion   S-10...
September 2017: Population Health Management
Gloria Tamborini, Concetta Piazzese, Roberto M Lang, Manuela Muratori, Elisa Chiorino, Massimo Mapelli, Laura Fusini, Sarah Ghulam Ali, Paola Gripari, Gianluca Pontone, Daniele Andreini, Mauro Pepi
BACKGROUND: Recently, a new automated software package (HeartModel) was developed to obtain three-dimensional (3D) left ventricular (LV) volumes using a model-based algorithm (MBA) with a "one-button" simple system and user-adjustable slider. The aims of this study were to verify the feasibility and accuracy of the MBA in comparison with other commonly used imaging techniques in a large unselected population, to evaluate possible accuracy improvements of free operator border adjustments or changes of the slider's default position, and to identify differences in method accuracy related to specific pathologies...
September 12, 2017: Journal of the American Society of Echocardiography
Aaron S Wallen, Michael W Morris, Beth A Devine, Jackson G Lu
Women's underperformance in MBA programs has been the subject of recent debate and policy interventions, despite a lack of rigorous evidence documenting when and why it occurs. The current studies document a performance gap, specifying its contours and contributing factors. Two behaviors by female students that may factor into the gap are public conformity and private internalization. We predicted that women conform to the norm associating maleness with technical prowess by minimizing their public assertiveness in class discussions and meetings, but that they do not internalize the norm by reducing private effort...
August 2017: Personality & Social Psychology Bulletin
Preeti Mehta, Balbir Singh Kaith
Present work offers use of semi-interpenetrating network (semi-IPN) and interpenetrating network (IPN) as the template for the synthesis of nano-hydroxyapatites. Semi-IPN and IPN of agar-gelatin were prepared and successfully used to synthesize nano-hydroxyapatite. Graft copolymerization technique was used to alter the properties of the hybrid backbone using ammonium persulphate as an initiator and N,N'methylene-bisacrylamide (MBA) as a crosslinker. The first step was to synthesize cross-linked semi-IPN of agar-gelatin blend which was converted to a cross-linked interpenetrating polymer...
September 6, 2017: International Journal of Biological Macromolecules
Lei Chen, Fan Zhang, Xin-Yu Deng, Xiangxin Xue, Li Wang, Yantao Sun, Jing-Dong Feng, Yongjun Zhang, Yaxin Wang, Young Mee Jung
A plasmon induced carrier movement enhanced mechanism of surface-enhanced Raman scattering (SERS) was investigated using a charge-transfer (CT) enhancement mechanism. Here, we designed a strategy to study SERS in Au@Cu2O nanoshell nanoparticles with different shell thicknesses. Among the plasmonically coupled nanostructures, Au spheres with Cu2O shells have been of special interest due to their ultrastrong electromagnetic fields and controllable carrier transfer properties, which are useful for SERS. Au@Cu2O nanoshell nanoparticles (NPs) with shell thicknesses of 48-56nm are synthesized that exhibit high SERS activity...
September 1, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
Agnieszka Kamińska, Katarzyna Winkler, Aneta Kowalska, Evelin Witkowska, Tomasz Szymborski, Anna Janeczek, Jacek Waluk
SERS-active nanostructures incorporated into a microfluidic device have been developed for rapid and multiplex monitoring of selected Type 1 cytokine (interleukins: IL-6, IL-8, IL-18) levels in blood plasma. Multiple analyses have been performed by using nanoparticles, each coated with different Raman reporter molecules: 5,5'-dithio-bis(2-nitro-benzoic acid) (DTNB), fuchsin (FC), and p-mercatpobenzoic acid (p-MBA) and with specific antibodies. The multivariate statistical method, principal component analysis (PCA), was applied for segregation of three different antigen-antibody complexes encoded by three Raman reporters (FC, p-MBA, and DTNB) during simultaneous multiplexed detection approach...
September 6, 2017: Scientific Reports
Sanghwa Lee, Youngsik Eom, Jeyoung Park, Jinhee Lee, Sang Youl Kim
A series of micro-hydrogel particles consisting of hyperbranched polyamidoamine (HPAMAM) without any supporting core materials was synthesized via the inverse suspension condensation polymerization of A2 and B4 monomers, N,N'-methylenebisacrylamide (MBA) and ethylenediamine (EDA). The particles were found to be highly effective when used to remove heavy metal ions, such as cadmium, copper, lead, nickel, zinc, and cobalt, from water, and they could be separated from the water by a simple filtration process. The results of this study demonstrate that crosslinked HPAMAM particles, which can be prepared by a simple and environmentally friendly process, are an attractive absorbent for water purification...
August 30, 2017: Scientific Reports
Tulika Malviya, Sneha Joshi, Lalit Mohan Dwivedi, Kirti Baranwal, Shehala, Arvind Kumar Pandey, Vandana Singh
Aloevera (AV) polysaccharide/acrylonitrile (AN) nanoparticles (AVANp4 of ∼50nm size have been crafted via free radical polymerization method using persulfate/ascorbic acid (KPS/AA) and methylenebisacrylamide (MBA) as the redox initiator and crosslinker respectively. AVANp4 was extensively characterized using FTIR, SEM, TEM, XRD, and Thermal analysis (TGA & DTG). Inclusion of AN in AV polysaccharide has been evidenced by nitrile stretching peak at 2244cm(-1) in FTIR spectrum of AVANp4. Colon specific targeted in-vitro release of 5-Aminosalicylic acid from AVANp4 has been studied in pH 1...
August 21, 2017: International Journal of Biological Macromolecules
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