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N Bock, J Ruehl, S Ruf
OBJECTIVES: The aim of this retrospective investigation was to assess the efficiency and outcome quality of Class II:1 treatment (Tx). MATERIAL AND METHODS: The investigation is based on the evaluation of all Class II:1 patients that ever (1986-2014) started Tx with a Herbst appliance and subsequently a multibracket appliance (MBA) at the study center. Study casts from before Tx, after Herbst-MBA Tx, and (if available) after ≥ 24 months of retention were evaluated using the Peer Assessment Rating (PAR) index, the Ahlgren scale, and standard occlusal variables...
December 8, 2017: Clinical Oral Investigations
Edwin Makhado, Sadanand Pandey, Philiswa N Nomngongo, James Ramontja
In this work, xanthan gum-cl-poly acrylic acid (XG-cl-pAA) hydrogel and xanthan gum-cl-poly acrylic acid/oxidized MWCNTs (XG-cl-pAA/o-MWCNTs) hydrogel nanocomposite was successfully surface modify by microwave assisted copolymerization, in which N, N'-methylenebisacrylamide (MBA) was used as a cross-linking agent. A copolymerization of acrylic acid (AA) onto xanthan gum (XG) initiated by microwave radiation method. Different weight percentages of oxidized MWCNTs were incorporated into the hydrogel matrix during the grafting reaction...
November 21, 2017: Journal of Colloid and Interface Science
Carrie Printz
No abstract text is available yet for this article.
December 15, 2017: Cancer
Jixin Yu, Elvis Genbo Xu, Yan Ren, Shiyu Jin, Tanglin Zhang, Jiashou Liu, Zhongjie Li
The mixture of bensulfuron-methyl and acetochlor (MBA) has been widely applied as a rice herbicide in China, but the mixture toxicity of MBA to aquatic organisms is largely unknown. The current study aims to investigate the acute effects of MBA to juvenile red swamp crayfish, Procambarus clarkii. Firstly, a 96 h semi-static exposure was conducted to determine the Lethal Concentration 50 (LC50) values at 24, 48, 72 and 96 h, as well as to assess the behavioral and morphological effects. A second 96 h exposure was conducted at an MBA concentration of 50% of the 96 h LC50 (72...
November 27, 2017: International Journal of Environmental Research and Public Health
Xóchitl López-Lozano, G Plascencia-Villa, G Calero, R L Whetten, Hans-Christian Weissker
The new water-soluble gold cluster Au146(p-MBA)57, the structure of which has been recently determined at sub-atomic resolution by Vergara et al., is the largest aqueous gold cluster ever structurally determined and likewise the smallest cluster with a stacking fault. The core presents a twinned truncated octahedron, while additional peripheral gold atoms follow a C2 rotational symmetry. According to the usual counting rules of the superatom complex (SAC) model, the compound attains a number of 92 SAC electrons if the overall net charge is 3- (three additional electrons)...
November 28, 2017: Nanoscale
Silvia Dalla Marta, Chiara Novara, Fabrizio Giorgis, Alois Bonifacio, Valter Sergo
In this work, we present a systematic study on solid Surface Enhanced Raman Scattering (SERS) substrates consisting of Au and Ag nanoparticles (NPs) loaded on filter paper with the dip-coating method. The aim of this work is to explore how a series of parameters (e.g., concentration of colloidal solution, different porosity of filter paper, and the presence of an aggregating agent) affects the analytical performance of paper-based SERS substrates. All the substrates developed in this study have been analyzed with two non-resonant probe molecules, 4-mercaptobenzoic acid (4-MBA) and adenine, in terms of (i) inter-sample repeatability, (ii) intra-sample repeatability, (iii) sensitivity, and (iv) overall SERS performance in terms of analyte quantification...
November 28, 2017: Materials
Glenna J Kramer, Justin R Nodwell
BACKGROUND: Cordyceps militaris is an insect pathogenic fungus that is prized for its use in traditional medicine. This and other entomopathogenic fungi are understudied sources for the discovery of new bioactive molecules. In this study, PacBio SMRT long read sequencing technology was used to sequence the genome of C. militaris with a focus on the genetic potential for secondary metabolite production in the genome assembly of this fungus. RESULTS: This is first chromosome level assembly of a species in the Cordyceps genera...
November 25, 2017: BMC Genomics
Bowen Yang, Alexander G Agrios
HYPOTHESIS: Molecular attachments to platinum have received far less study than binding to gold. Of particular interest is whether the binding of bifunctional molecules, containing both thiol and carboxyl groups, can attach platinum to surfaces such as metal oxides. EXPERIMENTS: Attachment of 4-mercaptobenzoic acid (4-MBA) to bulk and nanoparticulate platinum was studied by cyclic voltammetry (CV), Raman spectroscopy and X-ray photoelectron spectroscopy (XPS). Platinum nanoparticles were attached to TiO2 using 4-MBA and probed for Pt loading and electrocatalytic activity...
November 21, 2017: Journal of Colloid and Interface Science
Fahimeh Sadat Tabatabaei, Ramin Samadi, Saeed Tatari
BACKGROUND: Reconstruction of bone defects is often performed using bone autografts. However, limitations associated with the use of autografts led to the use of bone substitute materials. OBJECTIVES: The purpose of this study was to compare the surface characteristics of three commercially available grafts namely allografts, xenografts and alloplasts. METHODS: This in vitro study was conducted on beta-tricalcium phosphate (β-TCP) alloplast, a mixture of demineralized bone matrix and mineralized bone allograft (DBM&MBA) and natural bovine bone mineral (NBBM) xenograft...
2017: Bio-medical Materials and Engineering
Anthony D Turner, Stanislaw P Stawicki, Weidun Alan Guo
In response to systemic challenges facing the US healthcare system, many medical students, residents and practicing physicians are pursuing a Master in Business Administration (MBA) degree. The value of such proposition remains poorly defined. The aim of this review is to analyze current literature pertaining to the added value of MBA training for physician executives (PEs). We hypothesized that physicians who supplement their clinical expertise with business education gain a significant competitive advantage...
November 20, 2017: World Journal of Surgery
Lim Sze Lim, Noor Afizah Rosli, Ishak Ahmad, Azwan Mat Lazim, Mohd Cairul Iqbal Mohd Amin
pH-sensitive poly(acrylic acid) (PAA) hydrogel reinforced with cellulose nanocrystals (CNC) was prepared. Acrylic acid (AA) was subjected to chemical cross-linking using the cross-linking agent MBA (N,N-methylenebisacrylamide) with CNC entrapped in the PAA matrix. The quantity of CNC was varied between 0, 5, 10, 15, 20, and 25 wt %. X-ray diffraction (XRD) data showed an increase in crystallinity with the addition of CNC, while rheology tests demonstrated a significant increase in the storage modulus of the hydrogel with an increase in CNC content...
November 20, 2017: Nanomaterials
Miao Chen, Wen Luo, Zhimin Zhang, Ranhao Wang, Yuqiu Zhu, Hua Yang, Xiaoqing Chen
Surface-enhanced Raman scattering (SERS) based biosensing in biological fluids is constrained by nonspecific macromolecules adsorptions and disposable property of the SERS substrate. Here, novel multi-Au nanoparticles-embedded mesoporous silica microspheres (AuNPs/mSiO2) was prepared using a one-pot method, which served as reliable substrates for SERS enhancement associated with salient features of self-filtering ability and reusability. The fabrication and physical characterization of AuNPs/mSiO2 microspheres were discussed, and SERS activity of this novel substrates was investigated by using 4-mercaptobenzoic acid (4-MBA) as Raman probe...
November 15, 2017: ACS Applied Materials & Interfaces
Lynn B Bailey, Dorothy B Hausman
Reliable folate status data for women of reproductive age (WRA) to assess global risk for neural tube defects (NTDs) are needed. We focus on a recent recommendation by the World Health Organization that a specific "optimal" red blood cell (RBC) folate concentration be used as the sole indicator of NTD risk within a population and discuss how to best apply this guidance to reach the goal of assessing NTD risk globally. We also emphasize the importance of using the microbiologic assay (MBA) as the most reliable assay for obtaining comparable results for RBC folate concentration across time and countries, the need for harmonization of the MBA through use of consistent key reagents and procedures within laboratories, and the requirement to apply assay-matched cutoffs for folate deficiency and insufficiency...
November 15, 2017: Annals of the New York Academy of Sciences
Elodie Téclaire Ngo-Malabo, Paul Alain Ngoupo T, Martin Zekeng, Valérie Ngono, Laure Ngono, Serge Alain Sadeuh-Mba, Richard Njouom, Anfumbom Kfutwah
BACKGROUND: HIV infection in Cameroon is characterized by a great viral diversity with all HIV-1 groups (M, N, O, and P) and HIV-2 in circulation. HIV group determination is very important if tailored viral load analysis and treatments are to be applied. In our laboratory, HIV viral load is carried out using two platforms; Biocentric and Abbott depending on the HIV group identified. Biocentric which quantifies HIV-1 group M is a cheap and open system useful in resource limited settings...
November 14, 2017: Virology Journal
Tiia-Riikka Tero, Sami Malola, Benedek Koncz, Emmi Pohjolainen, Saara Lautala, Satu Mustalahti, Perttu Permi, Gerrit Groenhof, Mika Pettersson, Hannu Häkkinen
Ligand-stabilized, atomically precise gold nanoclusters with a metal core of a uniform size of just 1 - 3 nm constitute an interesting class of nanomaterials with versatile possibilities for applications due to their size dependent properties and modifiable ligand layers. The key to extending the usability of the clusters in applications is to understand the chemical bonding in the ligand layer as a function of cluster size and ligand structure. Previously, it has been shown that monodispersed gold nanoclusters, stabilized by meta-mercaptobenzoic acid (m-MBA or 3-MBA) ligands and with sizes of 68 to 144 gold atoms, show ambient stability...
November 14, 2017: ACS Nano
Jian Du, Chao Li, Yadong Zhao, Haisong Wang
Huge amount of waste hemicellulose liquor annually produced in China was burned or discharged into surrounding environment without further sufficient utilization, causing severely environmental issues. In order to solve this problem, this study aimed to find a way to effectively use aqueous waste hemicellulose solution from viscose fiber mills for bio-based materials development. Hereby, Polyacrylamide-Hemicellulose hybrid films were synthesized through the copolymerization of acrylamide (AM) monomers and hemicellulose initiated by potassium persulfate/N,N,N',N'-tetramethylethylenediamine (KPS/TMEDA) redox initiator system with cross-linker N,N-Methylene-bis(acrylamide) (MBA)...
November 8, 2017: International Journal of Biological Macromolecules
Charlotte Pushparajan, Shailesh K Goswami, Christopher J McAdam, Lyall R Hanton, Peter K Dearden, Stephen C Moratti, Andrew G Cridge
Polyacrylamide gel electrophoresis is a universal tool in a biochemist's toolkit for protein and nucleic acid separation and subsequent visualisation and analysis. The standard formulation of polyacrylamide gels consists of acrylamide (ACM) monomer crosslinked with bisacrylamide (MBA) which creates a gel with excellent sieving properties but which is mechanically fragile and prone to tearing during post-electrophoresis manipulations involved in visualisation and analysis. By adding a poly(ethylene oxide) macro-crosslinker to the standard gel formulation, we have created a tough gel matrix that can be used to fractionate proteins and nucleic acids by polyacrylamide gel electrophoresis...
November 10, 2017: Electrophoresis
Alonso N Gutierrez, Per H Halvorsen, Yi Rong
No abstract text is available yet for this article.
November 2017: Journal of Applied Clinical Medical Physics
Savvas Thysiadis, Sotirios Katsamakas, Panagiotis Dalezis, Theodora Chatzisideri, Dimitrios Trafalis, Vasiliki Sarli
AIM: Alkylating agents and antimetabolites are cytotoxic drugs commonly used in cancer treatment. These medications are often associated with serious side effects on normal tissues and organs. METHODOLOGY: To improve the pharmacological profile of the alkylating agent POPAM and the antimetabolite 5-fluorouracil, novel integrin-targeted delivery systems based on c(RGDyK) were successfully synthesized. The new conjugates were tested in vitro against different cancer cells such as PC3, SKOV3, A549, MCF7 and MBA-MB-321...
November 7, 2017: Future Medicinal Chemistry
Hai-Bin Liu, Xin-Jun Du, Yu-Xuan Zang, Ping Li, Shuo Wang
Rapid, sensitive, point-of-care detection of bacteria is extremely important in food safety. To address this requirement, we developed a new surface-enhanced Raman scattering (SERS)-based lateral flow (LF) strip biosensor combined with recombinase polymerase amplification (RPA) for simultaneous detection of Listeria monocytogenes and Salmonella Enterica Serotype Enteritidis. AuMBA@Ag core-shell nanoparticles were used in this SERS-LF. Highly sensitive quantitative detection is achieved by measuring the characteristic peak intensities of SERS tags...
November 2, 2017: Journal of Agricultural and Food Chemistry
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