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https://www.readbyqxmd.com/read/29924309/long-term-%C3%A2-15-years-effects-of-class-ii-treatment-a-longitudinal-and-cross-sectional-study-on-signs-and-symptoms-of-temporomandibular-disorders
#1
Sabine Ruf, Niko C Bock
Background: The aetiology of temporomandibular disorders (TMD) is controversial and post-orthodontic long-term TMD data of Class II populations are scarce. Objectives: To analyse the long-term (≥15 years) effects of Herbst-multibracket appliances (MBA) Class II treatment (Tx) on signs and symptoms of TMD. Subjects and methods: All patients (University of Giessen, Germany) who underwent Herbst-MBA Tx (end of active Tx ≥ 15 years ago), could be located and agreed to participate in a recall...
June 19, 2018: European Journal of Orthodontics
https://www.readbyqxmd.com/read/29923579/mesoporous-magnetic-silica-particles-modified-with-stimuli-responsive-p-nipam-dma-valve-for-controlled-loading-and-release-of-biologically-active-molecules
#2
Mustahida Tanjim, Mohammad A Rahman, Mohammad M Rahman, Hideto Minami, Sheikh M Hoque, Mostafa K Sharafat, Muhammad A Gafur, Hasan Ahmad
Mesoporous magnetic silica particles bearing a stimuli-responsive polymer valve were prepared and their performance as a microcapsule was evaluated. In this study, first, mesoporous magnetic iron oxide (Fe3O4) particles were prepared by a solvothermal method. Then, the magnetic particles were coated with silica and functionalized with vinyl groups using 3-(trimethoxysilyl)-propyl methacrylate (MPS). Subsequently, the Fe3O4/SiO2 composite particles grafted with MPS were used to carry out the seeded precipitation copolymerization of N-isopropylacrylamide (NIPAM) and 2,2-dimethylaminoethyl methacrylate (DMA)...
June 20, 2018: Soft Matter
https://www.readbyqxmd.com/read/29902719/surmounting-the-resistance-against-egfr-inhibitors-through-the-development-of-thieno-2-3-d-pyrimidine-based-dual-egfr-her2-inhibitors
#3
Sandra N Milik, Amal Kamal Abdel-Aziz, Deena S Lasheen, Rabah A T Serya, Saverio Minucci, Khaled A M Abouzid
In light of the emergence of resistance against the currently available EGFR inhibitors, our study focuses on tackling this problem through the development of dual EGFR/HER2 inhibitors with improved enzymatic affinities. Guided by the binding mode of the marketed dual EGFR/HER2 inhibitor, Lapatinib, we proposed the design of dual EGFR/HER2 inhibitors based on the 6-phenylthieno[2,3-d]pyrimidine as a core scaffold and hinge binder. After two cycles of screening aiming to identify the optimum aniline headgroup and solubilizing group, we eventually identified 27b as a dual EGFR/HER2 inhibitor with IC50 values of 91...
June 6, 2018: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/29894548/retention-and-stability-of-rigid-telescopic-and-milled-bar-attachments-for-implant-supported-maxillary-overdentures-an-in-vitro-study
#4
Moustafa Abdou ELsyad, Tarek Ahmed Soliman, Ahmed Khalifa Khalifa
PURPOSE: This study aimed to evaluate and compare the retention and stability of rigid telescopic and milled bar attachments for implant-supported maxillary overdentures. MATERIALS AND METHODS: An acrylic resin model of the edentulous maxilla without alveolar undercuts was fabricated, and four implants were inserted in the canine and second premolar areas of the model. Two experimental overdentures were constructed and connected to the model with either rigid telescopic (RTA) or milled bar (MBA) attachments...
June 12, 2018: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/29891789/design-synthesis-cytotoxic-evaluation-and-molecular-docking-of-new-fluoroquinazolinones-as-potent-anticancer-agents-with-dual-egfr-kinase-and-tubulin-polymerization-inhibitory-effects
#5
Mohamed F Zayed, Sahar Ahmed, Saleh Ihmaid, Hany E A Ahmed, Heba S Rateb, Sabrin R M Ibrahim
A series of new fluoroquinazolinone 6 ⁻ 8 and 10a ⁻ g derivatives was designed, prepared and screened for their in vitro cytotoxic activity against human cancer cell lines MCF-7 and MDA-MBA-231. Compounds 6 (IC50 = 0.35 ± 0.01 µM), 10f (IC50 = 0.71 ± 0.01 µM), 10d (IC50 = 0.89 ± 0.02 µM) and 10a (IC50 = 0.95 ± 0.01 µM) displayed broad spectrum anticancer activity better than the reference drug gefitinib (IC50 = 0.97 ± 0.02 µM) against MCF-7. Compounds 10e (IC50 = 0...
June 11, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29891299/preparation-and-characterization-of-cellulose-n-n-methylene-bisacrylamide-graphene-oxide-hybrid-hydrogels-and-aerogels
#6
Hongjuan Geng
Cellulose/N,N'-methylene bisacrylamide/graphene oxide hydrogels were prepared by mixing cellulose with N,N'-methylene bisacrylamide (MBA) and graphene oxide (GO) in NaOH/urea aqueous solution. Two states of hydrogels, i.e. the freshly prepared hydrogels and the hydrogels at swelling equilibrium state in deionized water, were prepared. The gelation time, mechanical properties, transparency, texture properties and water retention ratio of the hydrogels were investigated. Results showed that the cellulose solution showed obvious MBA and GO induced gelation behaviors...
September 15, 2018: Carbohydrate Polymers
https://www.readbyqxmd.com/read/29891295/novel-nanohydrogel-based-on-itaconic-acid-grafted-tragacanth-gum-for-controlled-release-of-ampicillin
#7
Deepak Pathania, Chetna Verma, Poonam Negi, Inderjeet Tyagi, Mohammad Asif, Nadavala Siva Kumar, Ebrahim H Al-Ghurabi, Shilpi Agarwal, Vinod Kumar Gupta
Nanohydrogel of tragacanth gum using microwave radiations is used for the controlled release of ampicillin. Tragacanth gum was grafted with itaconic acid, employing graft copolymerization in the presence of N, N1 -methylene-bis-acrylamide (MBA) as cross linker, and potassium persulphate as initiator. The prepared nanohydrogel was characterized using FTIR, XRD, SEM, and TEM. Besides, the hydrogel was evaluated for in vitro drug release in distilled water and different pH values, and antimicrobial efficacy against E...
September 15, 2018: Carbohydrate Polymers
https://www.readbyqxmd.com/read/29883198/bridging-the-expertise-gap-developing-and-utilizing-a-radiological-advisory-committee-for-new-york-city
#8
Mark L Maiello, Jessica Cole, Elaine Vernetti
From the Field is a semi-regular column that explores what it means to be a local health professional on the front lines of an emergency. Typically, National Association of County and City Health Officials (NACCHO) members share their stories of preparing for and responding to disasters, epidemics, and other major health issues. This month's column features a submission from the New York City health department that describes their experience in setting up a radiological advisory committee. Through exploring the analysis of the challenges faced and the solutions developed, readers can learn how these public health champions keep their communities safe even in extreme situations...
June 8, 2018: Health Security
https://www.readbyqxmd.com/read/29860470/assessment-of-quadrivalent-human-papillomavirus-vaccine-safety-using-the-self-controlled-tree-temporal-scan-statistic-signal-detection-method-in-the-sentinel-system
#9
W Katherine Yih, Judith C Maro, Michael Nguyen, Meghan A Baker, Carolyn Balsbaugh, David V Cole, Inna Dashevsky, Adamma Mba-Jonas, Martin Kulldorff
The self-controlled tree-temporal scan statistic-a new signal-detection method-can evaluate whether any of a wide variety of health outcomes are temporally associated with receipt of a specific vaccine, while adjusting for multiple testing. Neither health outcomes nor postvaccination potential periods of increased risk need be prespecified. Using US medical claims data in the Food and Drug Administration's Sentinel system, we employed the method to evaluate adverse events occurring after receipt of quadrivalent human papillomavirus vaccine (4vHPV)...
June 1, 2018: American Journal of Epidemiology
https://www.readbyqxmd.com/read/29850667/investigation-of-charge-transfer-between-a-4-mercaptobenzoic-acid-monolayer-and-tio-2-nanoparticles-under-high-pressure-using-surface-enhanced-raman-scattering
#10
Peng Li, Xiaolei Wang, Haiyan Li, Xuwei Yang, Xiaolei Zhang, Lixia Zhang, Yukihio Ozaki, Bingbing Liu, Bing Zhao
We investigated the CT process between a 4-mercaptobenzoic acid (4-MBA) monolayer and TiO2 NPs under high pressure using surface-enhanced Raman scattering (SERS). Employing the CT enhancement mechanism of semiconductors, we explore the CT process and explain how the pressure affects the process in the 4-MBA@TiO2 system.
May 31, 2018: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/29843427/one-step-synthesis-of-au-ag-nanowires-through-microorganism-mediated-ctab-directed-approach
#11
Luhang Xu, Dengpo Huang, Huimei Chen, Xiaoling Jing, Jiale Huang, Tareque Odoom-Wubah, Qingbiao Li
Synthesis and applications of one dimensional (1D) metal nanostructures have attracted much attention. However, one-step synthesis of bimetallic nanowires (NWs) has remained challenging. In this work, we developed a microorganism-mediated, hexadecyltrimethylammonium bromide (CTAB)-directed (MCD) approach to synthesize closely packed and long Au-Ag NWs with the assistance of a continuous injection pump. Characterization results confirmed that the branched Au-Ag alloy NWs was polycrystalline. And the Au-Ag NWs exhibited a strong absorbance at around 1950 nm in the near-infrared (NIR) region, which can find potential application in NIR absorption...
May 28, 2018: Nanomaterials
https://www.readbyqxmd.com/read/29802677/pure-organic-persistent-room-temperature-phosphorescence-at-both-crystalline-and-amorphous-states
#12
Tingting Zhang, Xuan Wang, Zhongfu An, Zhiwei Fang, Yongming Zhang, Wang Zhang Yuan
Persistent room temperature phosphorescence (p-RTP) of pure organic materials is attracting increasing attention. The design of efficient phosphors and understanding on the origin of p-RTP, however, remain challenging. Herein, to gain further insights into pure organic p-RTP, we prepared a group of carbazole (CZ) and methyl benzoate (MBA) conjugates with methyl ester unit at para (4-MBACZ), meta (3-MBACZ), and ortho (2-MBACZ) sites. These isomers merely produce prompt fluorescence in solutions, but generate blue prompt/delayed fluorescence (DF) and orange p-RTP with lifetimes up to 865...
May 26, 2018: Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry
https://www.readbyqxmd.com/read/29798678/a-new-alkylbenzoquinone-from-embelia-rowlandii-gilg-myrsinaceae
#13
Inest Larissa Tchomtchoua Bouzeko, Blanche Laure Ndontsa, Yves Martial Mba Nguekeu, Maurice Ducret Awouafack, Chin Piow Wong, James Deke Simo Mpetga, Roukayatou Mbouangouere, Pierre Tane, Hiroyuki Morita
A new alkylbenzoquinone named embeliquinone (1) together with five known compounds, lupeol (2), 3-O-[6'-O-palmitoyl-β-d-glucosyl]-spinasta-7,22(23)-diene (3), quercetin (4), (2S,3S,4R,8E)-2-[(2'R)-2'-hydroxy-heneicosanoylamino]-heneicosane-1,3,4-triol-8-ene (5), and β-sitosterol-3-O-β-d-glucopyranoside (6) were isolated from the MeOH leaf extract of Embelia rowlandii by using repeated open column chromatography techniques. The structure of the new compound was characterized by analyses of 1D- and 2D-NMR, and MS data...
May 25, 2018: Natural Product Research
https://www.readbyqxmd.com/read/29796255/alleviation-of-mycotoxin-biodegradation-agent-on-zearalenone-and-deoxynivalenol-toxicosis-in-immature-gilts
#14
Donghui Shi, Jianchuan Zhou, Lihong Zhao, Xiaoping Rong, Yu Fan, Humera Hamid, Wenqiang Li, Cheng Ji, Qiugang Ma
Background: The current study was carried out to evaluate the effects of mycotoxin biodegradation agent (MBA, composed of Bacillus subtilis ANSB01G and Devosia sp. ANSB714) on relieving zearalenone (ZEA) and deoxynivalenol (DON) toxicosis in immature gilts. Methods: A total of forty pre-pubertal female gilts (61.42 ± 1.18 kg) were randomly allocated to four diet treatments: CO (positive control); MO (negative control, ZEA 596.86 μg/kg feed and DON 796 μg/kg feed); COA (CO + 2 g MBA/kg feed); MOA (MO + 2 g MBA/kg feed)...
2018: Journal of Animal Science and Biotechnology
https://www.readbyqxmd.com/read/29794593/leadership-longevity-and-leaning-in-an-interview-with-mary-jo-joey-bulfin
#15
Angela S Prestia
This column profiles Mary Jo Bulfin, MBA, RN, CENP, chief executive officer of St. Mary's Medical Center, West Palm Beach, Florida. Ms Bulfin began her career as a staff nurse in the organization where she is now the CEO and discusses her career path and lessons learned.
June 2018: Journal of Nursing Administration
https://www.readbyqxmd.com/read/29789850/a-ag-synchronously-deposited-and-doped-tio-2-hybrid-as-an-ultrasensitive-sers-substrate-a-multifunctional-platform-for-sers-detection-and-photocatalytic-degradation
#16
Libin Yang, Qinqin Sang, Juan Du, Ming Yang, Xiuling Li, Yu Shen, Xiaoxia Han, Xin Jiang, Bing Zhao
Ag simultaneously deposited and doped TiO2 (Ag-TiO2) hybrid nanoparticles (NPs) were prepared via a sol-hydrothermal method, as both a sensitive surface-enhanced Raman scattering (SERS) substrate and a superior photocatalyst for the first time. Ag-TiO2 hybrid NPs exhibit excellent SERS performance for several probe molecules and the enhancement factor is calculated to be 1.86 × 105. The detection limit of the 4-mercaptobenzoic acid (4-MBA) probe on the Ag-TiO2 substrate is 1 × 10-9 mol L-1, which is four orders of magnitude lower than that on pure TiO2 as a consequence of the synergistic effects of TiO2 and Ag...
May 23, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29782162/water-and-fertilizer-integrated-hydrogel-derived-from-the-polymerization-of-acrylic-acid-and-urea-as-a-slow-release-n-fertilizer-and-water-retention-in-agriculture
#17
Dongdong Cheng, Yan Liu, Guiting Yang, Aiping Zhang
To reduce the preparation cost of superabsorbent and improve the N release rate at the same time, a novel low cost superabsorbent (SA) with the function of N slow release was prepared by chemical synthesis with neutralized acrylic acid (AA), urea, potassium persulfate (KPS) and N,N'-methylenebisacrylamide (MBA). The influence order of influence factors on water absorbency property was determined by orthogonal L18(3)7 experiment. Based on the optimization results of orthogonal experiment, the effects of single factor on the water absorption were studied, and the highest water absorbency (909 g/g) was obtained on the conditions: 1...
May 21, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29769106/peer-mentor-versus-teacher-delivery-of-a-physical-activity-program-on-the-effects-of-bmi-and-daily-activity-protocol-of-a-school-based-group-randomized-controlled-trial-in-appalachia
#18
Laureen H Smith, Rick L Petosa, Abigail Shoben
BACKGROUND: Rural Appalachian populations have poorer health and fewer positive health-related behaviors compared to other United States populations. Appalachians are the most sedentary U.S. population and teens are particularly sedentary. Obesity prevention through improving physical activity is a top priority in Rural Healthy People 2020. Obesity prevalence among Appalachian teens exceeds the national rates of 13.9% and has consistently been greater than 26%. Organized sports has not been effective at improving daily physical activity or health outcomes for Appalachian teens...
May 16, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29764830/palatal-tremor-as-a-manifestation-of-posterior-circulation-haemorrhagic-stroke
#19
Saed Alnaimat, Raghav Chandra, Shweta Gupta, Benjamin Mba
No abstract text is available yet for this article.
May 14, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29754611/highly-sensitive-and-visual-detection-of-guanosine-3-diphosphate-5-di-tri-phosphate-ppgpp-in-bacteria-based-on-copper-ions-mediated-4-mercaptobenzoic-acid-modified-gold-nanoparticles
#20
Jia Chen, Yanni Huang, Xiaoyan Yang, Haijuan Zhang, Zhan Li, Bo Qin, Xingguo Chen, Hongdeng Qiu
Guanosine 3'-diphosphate-5'-di(tri)phosphate (ppGpp) plays a crucial role in the gene expression, metabolism, growth, and other significant processes of microorganisms. In this work, a facile sensitive and visual strategy for the detection of ppGpp has been established by developing a colorimetric probe of copper ions (Cu2+ )-mediated 4-mercaptobenzoic acid (4-MBA) modified gold nanoparticles (AuNPs). The sensing process was characterized by transmission electron microscopy (TEM), zeta potential, dynamic light scattering (DLS) and UV-vis spectroscopy...
September 6, 2018: Analytica Chimica Acta
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