Read by QxMD icon Read


Hongjuan Geng
This work reports a "one-step" approach to make cellulose-based hydrogels in NaOH/urea aqueous solution via mixing N,N'-methylene bisacrylamide (MBA) with cellulose solution at room temperature. The hydrogels were revealed to be formed by an addition reaction between the double bonds of MBA and the hydroxyl groups of cellulose. Two states of hydrogels, i.e. the freshly prepared hydrogels and the hydrogels at swelling equilibrium state in deionized water, were prepared. Water retention of the hydrogels can reach up to 330 g H2 O/g dry hydrogel...
April 15, 2018: Carbohydrate Polymers
Robin Orr, Ben Schram, Rodney Pope
Law-enforcement officers increasingly wear body armour for protection; wearing body armour is common practice in military populations. Law-enforcement and military occupational demands are vastly different and military-styled body armour may not be suitable for law-enforcement. This study investigated differences between selected military body armour (MBA: 6.4 kg) and law-enforcement body armour (LEBA: 2.1 kg) in impacts on postural sway, vertical jump, agility, a functional movement screen (FMS), task simulations (vehicle exit; victim recovery), and subjective measures...
February 14, 2018: International Journal of Environmental Research and Public Health
Fangchao Bi, Shengli Ji, Henrietta Venter, Jingru Liu, Susan J Semple, Shutao Ma
3-Methoxybenzamide (3-MBA) derivatives have been identified as novel class of potent antibacterial agents targeting the bacterial cell division protein FtsZ. As one of isosteres for the amide group, 1,2,3-triazole can mimic the topological and electronic features of the amide, which has gained increasing attention in drug discovery. Based on these considerations, we prepared a series of 1H-1,2,3-triazole-containing 3-MBA analogues via isosteric replacement of the terminal amide with triazole, which had increased antibacterial activity...
February 2, 2018: Bioorganic & Medicinal Chemistry Letters
Tao Zuo, Jinshuai Shan, Yang Liu, Rong Xie, Xiaochun Yu, Chen Wu
N-Acetylgalactosaminyltransferase-14 (GALNT14) is a member of acetylgalactosaminyltransferases family. We have shown that GALNT14 could promote breast cancer cell invasion. However, the underlying molecular mechanism is unclear. Here, using yeast two hybrid, we find that EGF-containing fibulin-like extracellular matrix protein 2 (EFEMP2) interacts with GALNT14. Both in vitro and in vivo binding assays show that EFEMP2 is associated with GALNT14. Moreover, we find that GALNT14 mediates glycosylation of EFEMP2...
February 7, 2018: Translational Oncology
Rui Han, Wei Song, Xu Wang, Zhu Mao, Xiao Xia Han, Bing Zhao
Charge transfer (CT) at the interfaces between titanium dioxide (TiO2) and gold (Au) is investigated by surface-enhanced Raman scattering (SERS) spectroscopy probed by a sandwiched molecule 4-mercaptobenzoic acid (4-MBA). For the first time, the contribution of surface plasmon resonance (SPR) to CT is studied by tuning the surface plasmon absorption of Au nanorods (NRs) from 530 nm to 793 nm. Moreover, the degrees of CT in the TiO2-MBA-Au assemblies are calculated and the maximum degree of CT is obtained when the excitation laser wavelength is resonant with the SPR absorption of the assemblies...
February 9, 2018: Physical Chemistry Chemical Physics: PCCP
Irène Pegha-Moukandja, Roméo-Karl Imboumy-Limoukou, Nina Tchitoula-Makaya, Augustin-Ghislain Mouinga-Ondeme, Jean Claude Biteghe-Bi-Essone, Dieudonne Nkoghe Mba, Jean-Bernard Lekana-Douki, Fousseyni S Toure Ndouo
Plasmodium falciparum merozoite antigens (PfMAgs) play an essential role in the development of immunity to malaria. Currently, P. falciparum: protein 113 (Pf 113), apical membrane antigen 1 (AMA1), erythrocyte binding antigens (EBA175), and reticulocyte binding protein homologue 5 (RH5) are among the most PfMAgs studied. A comparative analysis of naturally acquired antibodies against these antigens in children would increase our knowledge about the development of protective immunity. Analysis of antibodies to Pf113, PfAMA1, PfEBA175, and PfRH5 was conducted in rural population during 2013 and 2014...
December 18, 2017: European Journal of Microbiology & Immunology
Gregory Roe, William Shaw, Joshua Darrall-Jones, Padraic J Phibbs, Dale Read, Jonathon J Weakley, Kevin Till, Ben Jones
The aim of the study was to assess the between-day reliability and validity of a medicine ball contained-accelerometer (MBA) for assessing upper-body neuromuscular performance during a throwing task. Ten professional rugby union players partook in the study. Between-day reliability was assessed from the best score attained during 2 sets of 3 throws, on 2 testing occasions separated by 7 days. Validity was assessed against a criterion measure (Optioelectronic system) during 75 throws from a sub group of three participants...
January 30, 2018: Journal of Strength and Conditioning Research
Bhawani Chamlagain, Tessa A Sugito, Paulina Deptula, Minnamari Edelmann, Susanna Kariluoto, Pekka Varmanen, Vieno Piironen
The in situ production of active vitamin B12 was investigated in aqueous cereal-based matrices with three strains of food-grade Propionibacterium freudenreichii. Matrices prepared from malted barley flour (33% w/v; BM), barley flour (6%; BF), and wheat aleurone (15%; AM) were fermented. The effect of cobalt and the lower ligand 5,6-dimethylbenzimidazole (DMBI) or its natural precursors (riboflavin and nicotinamide) on active B12 production was evaluated. Active B12 production was confirmed by UHPLC-UV-MS analysis...
January 2018: Food Science & Nutrition
Jing Xu, Zhongbin Wang, Chao Tan, Lei Si, Xinhua Liu
As a sound signal has the advantages of non-contacted measurement, compact structure, and low power consumption, it has resulted in much attention in many fields. In this paper, the sound signal of the coal mining shearer is analyzed to realize the accurate online cutting pattern identification and guarantee the safety quality of the working face. The original acoustic signal is first collected through an industrial microphone and decomposed by adaptive ensemble empirical mode decomposition (EEMD). A 13-dimensional set composed by the normalized energy of each level is extracted as the feature vector in the next step...
January 29, 2018: Sensors
Jia-Jung Ho, Ayanjeet Ghosh, Tianqi O Zhang, Martin T Zanni
Two-dimensional sum-frequency generation spectroscopy (2D SFG) is used to study the structures of the pentapeptide FGAIL on hydrogen bond promoting surfaces. FGAIL is the most amyloidogenic portion of the human islet amyloid polypeptide (hIAPP or amylin). In the presence of a pure gold surface, FGAIL does not form ordered structures. When the gold is coated with a self-assembled monolayer of mercaptobenzoic acid (MBA), 2D SFG spectra reveal features associated with β-sheets. Also observed are cross peaks between the FGAIL peptides and the carboxylic acid groups of the MBA monolayer, indicating that the peptides are in close contact with the surface headgroups...
January 25, 2018: Journal of Physical Chemistry. A
Jianzhi Zhang, Wanshan Li, Yiguo Dai, Li Shen, Jun Wu
Twenty-nine new limonoids-named xylomolins A₁-A₇, B₁-B₂, C₁-C₂, D-F, G₁-G₅, H-I, J₁-J₂, K₁-K₂, L₁-L₂, and M-N, were isolated from the seeds of the mangrove plant, Xylocarpus moluccensis. Compounds 1-13 are mexicanolides with one double bond or two conjugated double bonds, while 14 belongs to a small group of mexicanolides with an oxygen bridge between C1 and C8. Compounds 15-19 are khayanolides containing a Δ8,14 double bond, whereas 20 and 21 are rare khayanolides containing a Δ14,15 double bond and Δ8,9, Δ14,15 conjugated double bonds, respectively...
January 19, 2018: Marine Drugs
Andrew Philpott, Callum Lawford, Simon C Lau, Simon Chambers, Michael Bozin, Andrew Oppy
BACKGROUND: Open reduction and internal fixation of Lisfranc injuries has typically used multiple longitudinal incisions or a single transverse incision to approach the tarso-metatarsal joint (TMTJ). The incidence of wound-related complications is considerable. We describe a novel single-incision approach that utilizes subcutaneous windows to the medial TMTJ. METHODS: A retrospective review identified 150 patients who underwent open reduction and internal fixation for Lisfranc injuries, via the modified dorsal approach, at our center between January 2011 and June 2016...
January 1, 2018: Foot & Ankle International
Patrick M Flanigan, Arman Jahangiri, Joshua L Golubovsky, Jaret M Karnuta, Francis J May, Mitchel S Berger, Manish K Aghi
OBJECTIVE The position of neurosurgery department chair undergoes constant evolution as the health care landscape changes. The authors' aim in this paper was to characterize career attributes of neurosurgery department chairs in order to define temporal trends in qualities being sought in neurosurgical leaders. Specifically, they investigated the hypothesis that increased qualifications in the form of additional advanced degrees and research acumen are becoming more common in recently hired chairs, possibly related to the increased complexity of their role...
January 5, 2018: Journal of Neurosurgery
E A Dowlatshahi, Gfh Diercks, Mba van Doorn
No abstract text is available yet for this article.
January 4, 2018: BMJ: British Medical Journal
Jayabrata Maity, Samit Kumar Ray
The synthesis parameters for preparing a novel bio-composite adsorbent by integrating a copolymer of 2-hydroxyethyl methacrylate (HEMA), acrylamide (AM) and crosslinker N, N'-methylene bis acrylamide (MBA), polyethylene glycol (PEG) and Azadirachta Indica or Neem leaf (NL) and the process parameters for its subsequent use for adsorption of Pb(II) ion from water were optimized with central composite design (CCD) of response surface methodology (RSM). The structure of the bio-composite was characterized by FTIR, XRD, TGA, DMA, FESEM-EDX and PZC analysis...
December 26, 2017: Journal of Environmental Management
Tonghan Zhu, Zhenyu Lu, Jie Fan, Liping Wang, Guoliang Zhu, Yi Wang, Xia Li, Kui Hong, Pawinee Piyachaturawat, Arthit Chairoungdua, Weiming Zhu
Seven new ophiobolins (1-5, 12, and 14) along with the 11 known analogues (6-11, 13, 15-18) were isolated from the ethyl acetate extracts of the liquid and solid cultures of the mangrove fungus Aspergillus ustus 094102. The structures including the absolute configurations of the seven new compounds were elucidated by spectroscopic analysis, chemical methods, and quantum ECD calculations. Compounds 4-8 and 11-15 showed cytotoxicities against the G3K, MCF-7, MD-MBA-231, MCF/Adr, A549, and HL-60 human cancer cell lines with the IC50 values ranging from 0...
December 29, 2017: Journal of Natural Products
Judith M Persichilli, Janet S Puro
No abstract text is available yet for this article.
2017: MD Advisor: a Journal for New Jersey Medical Community
Hong-Sheng Zhang, Guang-Yuan Du, Zhong-Guo Zhang, Zhen Zhou, Hong-Liang Sun, Xiao-Ying Yu, Yu-Ting Shi, Dan-Ning Xiong, Hu Li, Ying-Hui Huang
High aerobic glycolysis not only provides energy to breast cancer cells, but also supports their anabolic growth. The redox sensitive transcription factor NRF2 is over-expressed in multiple cancers, including breast cancer. It is unclear whether NRF2 could promote breast cancer cell growth through enhancing glycolysis. In this study, we found that NRF2 and HIF1α mRNA and protein levels were significantly increased in MCF-7 and MDA-MB-231 breast cancer cells as compared to MCF-10A benign breast epithelial cells...
December 21, 2017: International Journal of Biochemistry & Cell Biology
Alexis Skoufalos, Janice L Clarke, Dana Rose Ellis, Vicki L Shepard, Elizabeth Y Rula
Rural Aging in America: Proceedings of the 2017 Connectivity Summit Alexis Skoufalos, EdD, Janice L. Clarke, RN, BBA, Dana Rose Ellis, BA, Vicki L. Shepard, MSW, MPA, and Elizabeth Y. Rula, PhD Editorial: Creating a Movement to Transform Rural Aging David B. Nash, MD, MBA, with Donato J. Tramuto, and Joseph F. Coughlin, PhD   S-3 Introduction   S-4 Summit Proceedings   S-5 Roundtable 1: The Power of Community - Enabling Social Connections and Access to Health Resources Through Community-Based Programs   S-5 Roundtable 2: Technology and Rural Health: Innovative Solutions to Bridge the Distance, Improve Care, and Deliver Programs   S-7 Roundtable 3: An Integrated Experience: The Exponential Potential of a Collaborative Approach to Rural Aging   S-8 General Discussion and Recommendations   S-8 Post-Summit Debriefing   S-9 Strategy and objectives   S-9 6-12 month action plan   S-9 Conclusion   S-9...
December 2017: Population Health Management
Tory V Whitten, Maureen M Sullivan, Stefan Saravia, Jayne Griffith, Joni M Scheftel, Richard N Danila
From the Field is a semi-regular column that explores what it means to be a local health professional on the front lines of an emergency. Typically, National Association of County and City Health Officials (NACCHO) members share their stories of preparing for and responding to disasters, epidemics, and other major health issues. This month's column features a submission from a state health department that describes their experience in investigating white powder incidents. Through exploring the analysis of the challenges faced and the solutions developed, readers can learn how these public health champions keep their communities safe even in extreme situations...
November 2017: Health Security
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"