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https://www.readbyqxmd.com/read/27904832/frontal-fibrosing-alopecia-treatment-options
#1
Raymond Fertig, Antonella Tosti
Frontal fibrosing alopecia (FFA) is a rare dermatologic disease that causes scarring and hair loss and is increasing in prevalence worldwide. FFA patients typically present with hair loss in the frontal scalp region and eyebrows which may be associated with sensations of itching or burning. FFA is a clinically distinct variant of lichen planopilaris (LPP) that affects predominantly postmenopausal women, although men and premenopausal women may also be affected. Early diagnosis and prompt treatment are necessary to prevent definitive scarring and permanent hair loss...
November 2016: Intractable & Rare Diseases Research
https://www.readbyqxmd.com/read/27901015/laser-induced-phase-separation-of-silicon-carbide
#2
Insung Choi, Hu Young Jeong, Hyeyoung Shin, Gyeongwon Kang, Myunghwan Byun, Hyungjun Kim, Adrian M Chitu, James S Im, Rodney S Ruoff, Sung-Yool Choi, Keon Jae Lee
Understanding the phase separation mechanism of solid-state binary compounds induced by laser-material interaction is a challenge because of the complexity of the compound materials and short processing times. Here we present xenon chloride excimer laser-induced melt-mediated phase separation and surface reconstruction of single-crystal silicon carbide and study this process by high-resolution transmission electron microscopy and a time-resolved reflectance method. A single-pulse laser irradiation triggers melting of the silicon carbide surface, resulting in a phase separation into a disordered carbon layer with partially graphitic domains (∼2...
November 30, 2016: Nature Communications
https://www.readbyqxmd.com/read/27896886/two-in-one-%C3%AE-orthogonal-photochemistry-on-a-radical-photoinitiating-system
#3
Silvana Hurrle, Andrea Lauer, Hartmut Gliemann, Hatice Mutlu, Christof Wöll, Anja S Goldmann, Christopher Barner-Kowollik
An alkyne functional radical photoinitiator, 2-(4-(2-hydroxy-2-methylpropanoyl)phenoxy)ethyl hex-5-ynoate, and evidence that both reactive moieties - the alkyne and the photoinitiator terminus - can be independently addressed with light of disparate wavelength (λ-orthogonality) are introduced. The alkyne functionality is subjected to a visible light (420 nm) induced copper-catalyzed Huisgen reaction, which is employed for the selective functionalization of the initiator with a poly(ethylene glycol) (PEG) chain...
November 29, 2016: Macromolecular Rapid Communications
https://www.readbyqxmd.com/read/27862848/safety-and-efficacy-of-rotational-atherectomy-for-the-treatment-of-undilatable-underexpanded-stents-implanted-in-calcific-lesions
#4
Luca A Ferri, Richard J Jabbour, Francesco Giannini, Susanna Benincasa, Marco Ancona, Damiano Regazzoli, Antonio Mangieri, Matteo Montorfano, Antonio Colombo, Azeem Latib
OBJECTIVES: Coronary stent underexpansion is a known risk factor for in-stent restenosis and stent thrombosis. There are limited options once noncompliant balloons have failed to achieve optimal stent expansion. Excimer Laser Coronary Angioplasty with contrast medium injection is one possibility, but not readily available. Rotational atherectomy is an alternative, and has been described in case reports, but concerns exist regarding safety. METHODS: All consecutive patients undergoing rotational atherectomy for symptomatic in-stent restenosis due to stent underexpansion resistant to noncompliant balloon postdilatation between January 2005 and December 2015 were analysed...
November 10, 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27843292/topography-modified-refraction-tmr-adjustment-of-treated-cylinder-amount-and-axis-to-the-topography-versus-standard-clinical-refraction-in-myopic-topography-guided-lasik
#5
Anastasios John Kanellopoulos
PURPOSE: To evaluate the safety, efficacy, and contralateral eye comparison of topography-guided myopic LASIK with two different refraction treatment strategies. SETTING: Private clinical ophthalmology practice. PATIENTS AND METHODS: A total of 100 eyes (50 patients) in consecutive cases of myopic topography-guided LASIK procedures with the same refractive platform (FS200 femtosecond and EX500 excimer lasers) were randomized for treatment as follows: one eye with the standard clinical refraction (group A) and the contralateral eye with the topographic astigmatic power and axis (topography-modified treatment refraction; group B)...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27828426/freeform-microlens-array-homogenizer-for-excimer-laser-beam-shaping
#6
Yuhua Jin, Ali Hassan, Yijian Jiang
We presented a novel technique to design microlens optical beam homogenizing system for excimer lasers. As a new approach by applying freeform surface microlens array, the homogenizer can yield somehow superior beam shaping results with larger but less microlens units than conventional method. With new concept and design, the diffraction effects at the microlens apertures can be reduced substantially. Large scale and highly uniform beam profile can be realized at a relative nearby working distance after beam shaping...
October 31, 2016: Optics Express
https://www.readbyqxmd.com/read/27824375/visual-outcomes-after-lasik-using-topography-guided-vs-wavefront-guided-customized-ablation-systems
#7
Ikuko Toda, Takeshi Ide, Teruki Fukumoto, Kazuo Tsubota
PURPOSE: To evaluate the visual performance of two customized ablation systems (wavefront-guided ablation and topography-guided ablation) in LASIK. METHODS: In this prospective, randomized clinical study, 68 eyes of 35 patients undergoing LASIK were enrolled. Patients were randomly assigned to wavefront-guided ablation using the iDesign aberrometer and STAR S4 IR Excimer Laser system (Abbott Medical Optics, Inc., Santa Ana, CA) (wavefront-guided group; 32 eyes of 16 patients; age: 29...
November 1, 2016: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/27802065/a-review-on-laser-and-light-based-therapies-for-alopecia-areata
#8
Stephanie Mlacker, Adam Souhail Aldahan, Brian James Simmons, Vidhi Shah, Colin Andrew McNamara, Sahal Samarkandy, Keyvan Nouri
Alopecia areata is a form of non-scarring alopecia that results from a hyperactive immune response of T cells against hair follicles. Many patients with visible hair loss experience psychological and emotional distress, as a result of their cosmetic disfigurement, and frequently seek treatment. However, existing treatment methods, such as corticosteroids, topical irritants, sensitizing agents, immunosuppressants, and psoralen plus ultraviolet light A may result in various adverse effects and often lack efficacy...
November 1, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27774802/-relationship-between-corneal-surface-temperature-and-air-flow-conditions-during-refractive-laser-eye-surgery-using-three-different-excimer-lasers
#9
Csaba Szekrényesi, Gábor László Sándor, Andrea Gyenes, Huba Kiss, Tamás Filkorn, Zoltán Nagy
INTRODUCTION: Thermal conditions during photorefractive keratectomy might be an important issue related to the corneal wound healing and long-term outcomes. AIM: Authors tried to find out the importance of temperature conditions during the treatment. METHOD: One eye of 90 patients has been included into the study. Photorefractive keratoctomy was applied with Carl Zeiss MEL 70, MEL 80 and Wavelight Allegretto excimer lasers. EBRO TLC 730 infrared thermometer was used for the measurement of surface temperature of the cornea before epithelial removal, as well as before and after the treatment...
October 2016: Orvosi Hetilap
https://www.readbyqxmd.com/read/27742773/novel-experience-of-laser-assisted-inside-out-central-venous-access-in-a-patient-with-bilateral-subclavian-vein-occlusion-requiring-pacemaker-implantation
#10
Thandar Aye, Thanh Trung Phan, Douglas Findlay Muir, Nicholas John Linker, Richard Hartley, Andrew John Turley
AIM: This new laser facilitated 'inside-out' technique was used for transvenous pacemaker insertion in a pacemaker-dependent patient with bilateral subclavian occlusion and a failed epicardial system who is not suitable for a transfemoral approach. METHOD AND RESULTS: Procedure was undertaken under general anaesthesia with venous access obtained from right femoral vein and left axillary vein. 7F multipurpose catheter was used to enter proximal edge of the occluded segment of subclavian vein via femoral approach, which then supported stiff angioplasty wires and microcatheters to tunnel into the body of occlusion...
October 14, 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/27739562/comparison-of-short-term-refractive-surgery-outcomes-after-wavefront-guided-versus-non-wavefront-guided-lasik
#11
Sarah Moussa, Alois Dexl, Eva Maria Krall, Marie Dietrich, Eva-Maria Arlt, Günther Grabner, Josef Ruckhofer
PURPOSE: To evaluate and compare visual and refractive outcomes after laser-assisted in situ keratomileusis (LASIK) surgery for the correction of myopia or myopic astigmatism using 3 different treatment protocols. METHODS: We included 736 eyes of 369 patients (age 18-62 years) divided into 3 groups: 235 eyes of 118 patients (MEL80 group) undergoing LASIK using optimized aspheric ablation profiles (MEL80 excimer laser; Carl Zeiss Meditec), 248 eyes of 124 patients (Wavescan group) undergoing wavefront-guided (WFG) LASIK (STAR S4IR excimer laser + Wavescan aberrometer; Abbott Medical Optics), and 253 eyes of 127 patients (iDesign group) undergoing WFG LASIK (STAR S4IR excimer laser + iDesign system; Abbott Medical Optics)...
October 10, 2016: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/27729265/laser-assisted-removal-of-embedded-vena-cava-filters-a-5-year-first-in-human-study
#12
William T Kuo, Justin I Odegaard, Jarrett K Rosenberg, Lawrence V Hofmann
BACKGROUND: Many patients are subjected to the potential risks and morbidity associated with an indwelling IVC filter when standard methods fail to remove the filter. We evaluated the safety and effectiveness of the excimer laser-sheath technique for removing embedded IVC filters. METHODS: Over a 5-year period, 251 consecutive patients undergoing laser-assisted filter retrieval were prospectively enrolled. There were 103 men and 148 women (mean:46 years, range:15-82)...
October 8, 2016: Chest
https://www.readbyqxmd.com/read/27709146/convex-and-concave-micro-structured-silicone-controls-the-shape-but-not-the-polarization-state-of-human-macrophages
#13
V Malheiro, F Lehner, V Dinca, P Hoffmann, K Maniura-Weber
The typical foreign body response (FBR) to synthetic implants is characterized by local inflammation and tissue fibrosis. Silicone implants have been associated with the development of adverse capsular contraction (ACC); a form of excessive FBR to the material that often requires the replacement of the implant. It has been shown that surface roughening of silicone can reduce the prevalence of ACC, but the mechanisms remain poorly understood. Macrophages are key cells in FBR. They exert their control mainly by polarizing into pro-inflammatory (M1) or pro-healing (M2) cells...
October 18, 2016: Biomaterials Science
https://www.readbyqxmd.com/read/27697248/outcomes-of-topography-guided-versus-wavefront-optimized-laser-in-situ-keratomileusis-for-myopia-in-virgin-eyes
#14
Arun Kumar Jain, Chintan Malhotra, Anand Pasari, Pawan Kumar, Majid Moshirfar
PURPOSE: To compare the outcomes of topography-guided and wavefront-optimized treatment in patients having laser in situ keratomileusis (LASIK) for myopia. SETTING: Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India. DESIGN: Prospective contralateral-eye case study. METHODS: Patients had topography-guided LASIK in 1 eye and wavefront-optimized LASIK in the contralateral eye using the Customized Refractive Surgery Master software and Mel 80 excimer laser...
September 2016: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/27686663/effects-of-mydrin-eye-drops-on-central-corneal-thickness-values-in-adult-patients-with-myopia
#15
Yuan Zeng, Jian-Hua Gao
OBJECTIVE: This study aimed to evaluate the effect of Mydrin eye-drops on central corneal thickness values and investigate the duration of the effect. METHODS: In this prospective randomised self-controlled study, we enrolled 60 myopic patients (120 eyes) undergoing corneal laser refractive surgery. The central corneal thickness was measured before and one and four hours after administration of Mydrin eye-drops (major components are tropicamide and phenylephrine hydrochloride) using the Orbscan II anterior segment analysis system and a SP-2000P non-contact specular microscope, respectively...
September 29, 2016: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/27680219/a-randomised-half-body-prospective-study-of-low-and-medium-dose-regimens-using-the-308%C3%A2-nm-excimer-laser-in-the-treatment-of-localised-psoriasis
#16
Eleanor Higgins, Nicola Ralph, Sheila Ryan, Nicola Koik, Bahman Honari, Aoife Lally, Paul Collins
This study compared two dose-escalation regimens using the 308 nm excimer laser treating localised plaque psoriasis, to determine the optimal regimen. A randomised, left-right body trial was designed including patients aged >18 years with localised plaque psoriasis (<10% body surface area). The standard/low dose regimen started at 70% of the minimal erythema dose (MED), with 20% dose increments. The medium dose regimen commenced at 200% MED, with 25% increments. Patients were treated until disease clearance or a maximum of 36 treatments...
September 29, 2016: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/27650935/prevalence-indications-and-management-of-balloon-uncrossable-chronic-total-occlusions-insights-from-a-contemporary-multicenter-us-registry
#17
Judit Karacsonyi, Dimitri Karmpaliotis, Khaldoon Alaswad, Farouc A Jaffer, Robert W Yeh, Mitul Patel, John Bahadorani, Anthony Doing, Ziad A Ali, Aris Karatasakis, Barbara A Danek, Bavana V Rangan, Aya J Alame, Subhash Banerjee, Emmanouil S Brilakis
BACKGROUND: Balloon uncrossable lesions can be challenging to treat, requiring specialized techniques and equipment. METHODS: We examined the prevalence, clinical and angiographic characteristics, management and procedural outcomes of balloon uncrossable lesions in a multicenter chronic total occlusion (CTO) percutaneous coronary intervention (PCI) registry. RESULTS: Between 2012 and 2016, 718 CTO PCIs (in which the occlusion was successfully crossed with a guidewire) were performed in 701 patients at 11 US centers...
September 21, 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27640798/-not-available
#18
Li Lei, Jinhua Huang, Qinghai Zeng, Caiyun Xi, Aiyuan Guo, Jing Chen
OBJECTIVE: To evaluate the efficacy and influential factors for 308 nm excimer laser in the treatment of stable vitiligo patients.
 METHODS: A total of 207 stable vitiligo patients with 1 763 patches were treated with 308 nm excimer laser. Open-label study was carried out to investigate the efficacy and safety regarding the treatment with 308 nm excimer laser, and to compare the response under different conditions including gender, age, duration, lesion location, and hair color...
September 28, 2016: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/27638440/phototherapy-for-atopic-dermatitis
#19
Dorothy L Rodenbeck, Jonathan I Silverberg, Nanette B Silverberg
Phototherapy is a second-line treatment for moderate to severe atopic dermatitis (AD) that effectively decreases cutaneous inflammation with minimal or no systemic side effects. Children in grade school, adolescents, and adults may benefit from phototherapy, when they have chronic AD refractory to first-line topical treatments. This review focuses on six approaches for phototherapy in AD: (1) broadband ultraviolet B (UVB), (2) Goeckerman regimen (coal tar + broadband UVB), (3) narrowband UVB, (4) excimer lasers for targeted areas, (5) combination UVA/UVB, and (6) UVA-1...
September 2016: Clinics in Dermatology
https://www.readbyqxmd.com/read/27638437/ultraviolet-b-radiation-therapy-for-psoriasis-pursuing-the-optimal-regime
#20
Tiago R Matos, Tsui C Ling, Vaneeta Sheth
Psoriasis is a chronic and common disease mediated by resident memory T cells that negatively affects a broad range of people worldwide. One of the oldest and most commonly used treatments is phototherapy. We reviewed the existing literature on the four main ultraviolet B (UVB) modalities of phototherapy in the management of psoriasis: heliotherapy, broadband UVB, narrowband UVB, and excimer laser and lamp. Despite the many studies done on these therapies, there is significant variation in their prescription and use...
September 2016: Clinics in Dermatology
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