Samantha Lee, Hind Sbihi, Julia L MacIsaac, Robert Balshaw, Amirthagowri Ambalavanan, Padmaja Subbarao, Piushkumar J Mandhane, Theo J Moraes, Stuart E Turvey, Qingling Duan, Michael Brauer, Jeffrey R Brook, Michael S Kobor, Meaghan J Jones
BACKGROUND: Evidence suggests that prenatal air pollution exposure alters DNA methylation (DNAm), which could go on to affect long-term health. It remains unclear whether DNAm alterations present at birth persist through early life. Identifying persistent DNAm changes would provide greater insight into the molecular mechanisms contributing to the association of prenatal air pollution exposure with atopic diseases. OBJECTIVES: This study investigated DNAm differences associated with prenatal nitrogen dioxide (<mml:math xmlns:mml="https://www...
April 2024: Environmental Health Perspectives