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https://www.readbyqxmd.com/read/27154828/application-of-multivariate-statistics-to-the-steroidal-module-of-the-athlete-biological-passport-a-proof-of-concept-study
#1
Eugenio Alladio, Roberto Caruso, Enrico Gerace, Eleonora Amante, Alberto Salomone, Marco Vincenti
The Technical Document TD2014EAAS was drafted by the World Anti-Doping Agency (WADA) in order to fight the spread of endogenous anabolic androgenic steroids (EAAS) misuse in several sport disciplines. In particular, adoption of the so-called Athlete Biological Passport (ABP) - Steroidal Module allowed control laboratories to identify anomalous EAAS concentrations within the athletes' physiological urinary steroidal profile. Gas chromatography (GC) combined with mass spectrometry (MS), indicated by WADA as an appropriate technique to detect urinary EAAS, was utilized in the present study to develop and fully-validate an analytical method for the determination of all EAAS markers specified in TD2014EAAS, plus two further markers hypothetically useful to reveal microbial degradation of the sample...
May 30, 2016: Analytica Chimica Acta
https://www.readbyqxmd.com/read/26699684/soccer-players-awarded-one-or-more-red-cards-exhibit-lower-2d-4d-ratios
#2
Alvaro Mailhos, Abraham P Buunk, Denise Del Arca, Verónica Tutte
Anatomical, cognitive and behavioral sex differences are widely recognized in many species. It has been proposed that some of these differences might result from the organizing effects of prenatal sex steroids. In humans, males usually exhibit higher levels of physical aggression and prowess. In this study, we analyze the relationship between second-to-fourth digit (2D:4D) ratios-a proxy for prenatal androgen levels-and foul play and sporting performance in a sample of junior soccer players from a professional Uruguayan soccer club...
September 2016: Aggressive Behavior
https://www.readbyqxmd.com/read/26645724/knee-orthoses-for-treating-patellofemoral-pain-syndrome
#3
REVIEW
Toby O Smith, Benjamin T Drew, Toby H Meek, Allan B Clark
BACKGROUND: Patellofemoral pain syndrome (PFPS) is a painful musculoskeletal condition, which is characterised by knee pain located in the anterior aspect (front) and retropatellar region (behind) of the knee joint. Various non-operative interventions are suggested for the treatment of this condition. Knee orthoses (knee braces, sleeves, straps or bandages) are worn over the knee and are thought to help reduce knee pain. They can be used in isolation or in addition to other treatments such as exercise or non-steroidal anti-inflammatory medications...
December 8, 2015: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26615768/diaphyseal-tibiofibular-synostosis-in-professional-athletes-report-of-2-cases
#4
B Sonnery-Cottet, M Alessio-Mazzola, B F Luz, N C Barbosa, S Tuteja, C Kajetanek, A Dellal, M Thaunat
Anterior leg pain is common in professional athletes and tibiofibular synostosis is reported to be a rare cause of anterior compartment pain or ankle pain related to sports activities. The management and appropriate treatment of this condition in professional athletes is controversial and the literature on the topic is sparse. Distal synostosis is usually related to ankle sprain and syndesmotic ligament injury, and proximal synostosis has been linked to leg length discrepancy and exostosis. Mid-shaft synostosis is even less common than proximal and distal forms...
February 2016: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/25942014/effects-of-resistance-exercise-and-the-use-of-anabolic-androgenic-steroids-on-hemodynamic-characteristics-and-muscle-damage-markers-in-bodybuilders
#5
Azadeh Nasseri, Amir Nadimi, Saeed D Nikookheslat
BACKGROUND: Anabolic androgenic steroids (AAS), synthetic compounds of testosterone commonly used as sport performance enhancers, could cause cardiovascular dysfunction and cell damage. Even though the side effects of AAS intake have been widely studied, yet little is known about how resistance exercise can alter these side effects. This study aimed to determine the effects of one session resistance exercise and the use of AAS on hemodynamic characteristics and muscle damage markers in professional bodybuilders...
September 2016: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/25878074/high-prevalence-of-medication-use-in-professional-football-tournaments-including-the-world-cups-between-2002-and-2014-a-narrative-review-with-a-focus-on-nsaids
#6
REVIEW
Philippe M Tscholl, Martin Vaso, Alexis Weber, Jiri Dvorak
The use of medication in international football has been monitored since the 2002 FIFA World Cup. Team physicians were asked to provide information on prescribed medication 72 h prior to each match for every player. 69% of adult male players reported using medication, with more than half the players using non-steroidal anti-inflammatory drugs (NSAIDs). Up to one-third of all players used NSAIDs prior to every match, regardless of whether they took the field or not. The mean intake of medication was significantly higher during the FIFA Women's World Cup (0...
May 2015: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/25828698/-cardiovascular-alterations-associated-with-doping
#7
D Thieme, A Büttner
Doping -the abuse of anabolic-androgenic steroids in particular- is widespread in amateur and recreational sports and does not solely represent a problem of professional sports. Excessive overdose of anabolic steroids is well documented in bodybuilding or powerlifting leading to significant side effects. Cardiovascular damages are most relevant next to adverse endocrine effects.Clinical cases as well as forensic investigations of fatalities or steroid consumption in connection with trafficking of doping agents provide only anecdotal evidence of correlations between side effects and substance abuse...
May 2015: Herz
https://www.readbyqxmd.com/read/25001661/salivary-steroid-hormone-response-to-whole-body-cryotherapy-in-elite-rugby-players
#8
D Grasso, P Lanteri, C Di Bernardo, C Mauri, S Porcelli, A Colombini, V Zani, F G Bonomi, G Melegati, G Banfi, G Lombardi
Saliva represents a low stress, not-invasively collected matrix that allows steroid hormone monitoring in athletes by reflecting type, intensity and duration of exercise. Whole body cryotherapy (WBC) consists of short whole-body exposures to extremely cold air (-110° to -140°C) which, despite being initially used to treat inflammatory diseases, is currently acquiring increasing popularity in sports medicine. Cryostimulation practice is now widely accepted as an effective treatment to accelerate muscle recovery in rugby players...
April 2014: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/24670606/-in-process-citation
#9
Andreas Bieri, Matthias Kamber, Martin Sterchi, Primus E Mullis
BACKGROUND: Over the last years, various revelations demonstrated that the doping problem is far from being solved. These included the American cyclist Lance Armstrong's disclosure and subsequent conviction for doping abuse over a period of many years. Furthermore, these revelations underlined the importance of strong and independent national antidoping agencies (NADA). During the current revision process of the World Anti-Doping Programme (WADP), Antidoping Switzerland is campaigning for national anti-doping agencies to have the same rights, the same authority and the same degree of responsibility as international sports associations...
April 2014: Therapeutische Umschau. Revue Thérapeutique
https://www.readbyqxmd.com/read/24635395/detecting-doping-use-more-than-an-analytical-problem
#10
J R Delanghe, T M Maenhout, M M Speeckaert, M L De Buyzere
The recent Armstrong case, where more than 250 negative doping tests are confronted with the athlete's confession of erythropoietin use, blood doping, steroid, and growth hormone abuse, illustrates the limitations of current laboratory tests in detecting doping in sport. Despite numerous doping controls and simultaneous indications of common doping abuse among professional athletes in the last two decades, the number of positive urine tests for recombinant human erythropoietin (rHuEPO) remains remarkably low...
January 2014: Acta Clinica Belgica
https://www.readbyqxmd.com/read/23855363/national-athletic-trainers-association-position-statement-conservative-management-and-prevention-of-ankle-sprains-in-athletes
#11
REVIEW
Thomas W Kaminski, Jay Hertel, Ned Amendola, Carrie L Docherty, Michael G Dolan, J Ty Hopkins, Eric Nussbaum, Wendy Poppy, Doug Richie
OBJECTIVE: To present recommendations for athletic trainers and other allied health care professionals in the conservative management and prevention of ankle sprains in athletes. BACKGROUND: Because ankle sprains are a common and often disabling injury in athletes, athletic trainers and other sports health care professionals must be able to implement the most current and evidence-supported treatment strategies to ensure safe and rapid return to play. Equally important is initiating preventive measures to mitigate both first-time sprains and the chance of reinjury...
July 2013: Journal of Athletic Training
https://www.readbyqxmd.com/read/23788681/operative-and-nonoperative-treatment-of-cervical-disc-herniation-in-national-football-league-athletes
#12
Dennis S Meredith, Kristofer J Jones, Ronnie Barnes, Scott A Rodeo, Frank P Cammisa, Russell F Warren
BACKGROUND: Limited evidence exists to guide clinical decision making regarding cervical disc herniations in professional athletes playing for the National Football League (NFL) in the United States. PURPOSE: To describe the presentation and treatment outcomes of cervical disc herniations in NFL athletes with a focus on safety and return to sport. STUDY DESIGN: Case series; Level of evidence, 4. METHODS: The records of a single NFL team and its consulting physicians were reviewed from 2000 to 2011...
September 2013: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/23613517/a-retrospective-30-year-follow-up-study-of-former-swedish-elite-male-athletes-in-power-sports-with-a-past-anabolic-androgenic-steroids-use-a-focus-on-mental-health
#13
A S Lindqvist, T Moberg, B O Eriksson, C Ehrnborg, T Rosén, C Fahlke
BACKGROUND: The knowledge concerning the long-term effect of former anabolic androgenic steroids (AAS)-use on mental health is sparse. AIM: This study aims to investigate whether previous AAS-use affects mental health, present sociodemographic data, sport activity and substance abuse in a retrospective 30-year follow-up study of former elite athletes. METHODS: Swedish male-elite power sport athletes (n=683) on the top 10 national ranking lists during any of the years 1960-1979 in wrestling, Olympic lifting, powerlifting and the throwing events in track and field answered a questionnaire...
October 2013: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/23317577/ultra-high-performance-liquid-chromatography-tandem-mass-spectrometry-determination-and-profiling-of-prohibited-steroids-in-human-biological-matrices-a-review
#14
REVIEW
Fabio Gosetti, Eleonora Mazzucco, Maria Carla Gennaro, Emilio Marengo
The use of doping agents, once restricted to professional athletes, has nowadays become a problem of public health, since it also concerns young people and non-competing amateurs in different sports. The use is also diffused in social life for improving physical appearance and enhancing performance and even dietary supplements assumed to improve performance often contain anabolic steroids. While decades ago the so-called "classical doping agents" (like stimulants and narcotics) were used, to-day anabolic steroids are more widely diffused...
May 15, 2013: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/23200722/acute-inguinal-pain-associated-with-iliopectineal-bursitis-in-four-professional-soccer-players
#15
S Brunot, S Dubeau, H Laumonier, A Creusé, T Delmeule, G Reboul, D Das Neves, H Bouin
Four professional soccer players were investigated for acute or subacute pain in the inguinal region. Clinical tests were negative for an inguinal hernia or adductor tendinitis. Resisted hip flexion caused pain. MRI in these four patients showed the onset of iliopectineal bursitis, with signal abnormalities predominantly at the periphery of the psoas tendon in contact with the iliopectineal eminence. Ultrasound-guided steroid injection allowed the two players injected to continue their sporting activity. The two other players were treated by 3 and 7 days rest and oral anti-inflammatory treatment...
January 2013: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/23097484/performance-enhancing-drug-abuse-and-cardiovascular-risk-in-athletes-implications-for-the-clinician
#16
REVIEW
Peter J Angell, Neil Chester, Nick Sculthorpe, Greg Whyte, Keith George, John Somauroo
The use of performance-enhancing and social drugs by athletes raises a number of ethical and health concerns. The World Anti-Doping Agency was constituted to address both of these issues as well as publishing a list of, and testing for, banned substances in athletes. Despite continuing methodological developments to detect drug use and associated punishments for positive dope tests, there are still many athletes who choose to use performance and image enhancing drugs. Of primary concern to this review are the health consequences of drug use by athletes...
November 2012: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/23068595/national-athletic-trainers-association-position-statement-anabolic-androgenic-steroids
#17
Robert D Kersey, Diane L Elliot, Linn Goldberg, Gen Kanayama, James E Leone, Mike Pavlovich, Harrison G Pope
OBJECTIVE: This manuscript summarizes the best available scholarly evidence related to anabolic-androgenic steroids (AAS) as a reference for health care professionals, including athletic trainers, educators, and interested others. BACKGROUND: Health care professionals associated with sports or exercise should understand and be prepared to educate others about AAS. These synthetic, testosterone-based derivatives are widely abused by athletes and nonathletes to gain athletic performance advantages, develop their physiques, and improve their body image...
September 2012: Journal of Athletic Training
https://www.readbyqxmd.com/read/22938637/chronic-ankle-instability
#18
REVIEW
Juan Bernardo Gerstner Garces
Chronic instability of the ankle and anterolateral impingement syndrome are abnormalities that present as a result of inversion and forced plantar-flexion traumas of the foot, despite strict conservative management in the ER and in rehabilitation. A conservative approach is always the first choice of treatment, including anti-inflammatory medications, rehabilitation and proprioception, infiltration with steroids in impingement cases, and use of orthotics, whose true effectiveness is the subject of multiple studies and much debate...
September 2012: Foot and Ankle Clinics
https://www.readbyqxmd.com/read/22697190/managing-psychiatric-issues-in-elite-athletes
#19
Ira D Glick, Mark A Stillman, Claudia L Reardon, Eva C Ritvo
OBJECTIVE: Providing psychiatric consultation to elite athletes presents unique and complex issues. These patients present with multifaceted medical, psychological, and performance concerns. We provide the first report of professional and ethical quandaries that arise in treating elite athletes and ways to address them. METHOD: We identified studies through a MEDLINE search. Search terms included the following, individually and in combination: psychiatry, athletes, elite athletes, professional athletes, sports, sport psychiatry, mental illness, major depressive disorder, depression, bipolar disorder, suicide, anxiety, generalized anxiety disorder, obsessive compulsive disorder, social phobia, social anxiety disorder, panic disorder, post traumatic stress disorder, specific phobia, psychosis, eating disorders, anorexia nervosa, bulimia nervosa, attention deficit hyperactivity disorder, substance abuse, substance dependence, addiction, alcohol, anabolic steroids, stimulants, antidepressants, mood stabilizers, anxiolytics, antipsychotics, sedative-hypnotics, psychotropics, medications, and psychiatric medications...
May 2012: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/22080903/screening-indicators-of-dehydroepiandosterone-androstenedione-and-dihydrotestosterone-use-a-literature-review
#20
REVIEW
Melinda K Shelby, Dennis J Crouch, David L Black, Timothy A Robert, Rebecca Heltsley
Because of their perceived and reported effects on self-image, muscle development, performance, and similar factors, anabolic-androgenic steroids (AAS) and their precursors are among the most abused substances by professional, amateur, and recreational athletes. However, AAS abuse is not limited to athletes, but is also prevalent in the workplace, especially those professions in which image, strength, and endurance are coveted attributes. The detection of many steroids in biological specimens is analogous to the detection of an abused drug such as cocaine...
November 2011: Journal of Analytical Toxicology
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