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substance use in pregnancy

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https://www.readbyqxmd.com/read/29145136/lead-cadmium-and-arsenic-in-human-milk-and-their-socio-demographic-and-lifestyle-determinants-in-lebanon
#1
Maya Bassil, Farah Daou, Hussein Hassan, Osama Yamani, Joelle Abi Kharma, Zouheir Attieh, Jomana Elaridi
INTRODUCTION: Exposure of newborns to toxic metals is of special interest due to their reported contamination in breast milk and potential harm. The aim of this study was to assess the occurrence and factors associated with lead, cadmium and arsenic contamination in breast milk collected from lactating mothers in Lebanon. METHODS: A total of 74 breast milk samples were collected from primaparas according to guidelines set by the World Health Organization. A survey was administered to determine the demographic and anthropometric characteristics of participating lactating mothers...
October 27, 2017: Chemosphere
https://www.readbyqxmd.com/read/29142264/impairment-of-bkca-channels-in-human-placental-chorionic-plate-arteries-is-potentially-relevant-to-the-development-of-preeclampsia
#2
Mengzhou He, Fanfan Li, Meitao Yang, Yao Fan, Rajluxmee Beejadhursing, Yin Xie, Yuan Zhou, Dongrui Deng
Preeclampsia has known associations with insufficient placental perfusion. The large-conductance Ca(2+)-activated K(+) (BKca) channels that have recently been found to play important roles in cellular growth and vasodilatation could potentially participate in the development of preeclampsia. However, the mechanisms by which downregulated BKca channels are involved in the development of preeclampsia remain unknown. In this study, we investigated the mechanism(s) underlying the impairment of vascular tone regulation by BKca channels in human placental chorionic plate arteries (CPAs) in preeclampsia...
November 16, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/29140822/optimizing-pregnancy-treatment-interventions-for-moms-opti-mom-a-pilot-study
#3
Gerald T Cochran, Valerie Hruschak, Walitta Abdullah, Elizabeth Krans, Antoine B Douaihy, Stephanie Bobby, Rachel Fusco, Ralph Tarter
OBJECTIVES: The public health burden of opioid use disorder (OUD) among pregnant women has significantly increased in recent years. The Optimizing Pregnancy Treatment Interventions for Moms study was a pilot project that examined the feasibility of a patient navigation (PN) intervention model to reduce substance use and improve mental health, quality of life, and to increase engagement with treatment services among pregnant women with OUD. METHODS: A 1-group repeated-measures pilot study was conducted with treatment-seeking pregnant women with opioid dependence initiating buprenorphine maintenance treatment...
November 14, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/29138022/to-which-mixtures-are-french-pregnant-women-mainly-exposed-a-combination-of-the-second-french-total-diet-study-with-the-eden-and-elfe-cohort-studies
#4
T Traoré, A Forhan, V Sirot, M Kadawathagedara, B Heude, M Hulin, B de Lauzon-Guillain, J Botton, M A Charles, A Crépet
Pregnant women and their unborn child are exposed to a large number of substances during pregnancy. Some of these substances may cross the placenta, resulting in exposure of the foetus. There is growing evidence that certain substances could interact to produce a mixture effect. It is therefore essential to identify the main mixtures mothers are exposed to. This study aimed to identify the major mixtures French pregnant women included in EDEN and ELFE cohorts were exposed to, on the basis of the 441 substances analysed in the second French total diet study...
November 11, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29135438/exposure-to-perfluoroalkyl-substances-and-metabolic-outcomes-in-pregnant-women-evidence-from-the-spanish-inma-birth-cohorts
#5
Nuria Matilla-Santander, Damaskini Valvi, Maria-Jose Lopez-Espinosa, Cyntia B Manzano-Salgado, Ferran Ballester, Jesús Ibarluzea, Loreto Santa-Marina, Thomas Schettgen, Mònica Guxens, Jordi Sunyer, Martine Vrijheid
BACKGROUND: Exposure to perfluoroalkyl substances (PFASs) may increase risk for metabolic diseases; however, epidemiologic evidence is lacking at the present time. Pregnancy is a period of enhanced tissue plasticity for the fetus and the mother and may be a critical window of PFAS exposure susceptibility. OBJECTIVE: We evaluated the associations between PFAS exposures and metabolic outcomes in pregnant women. METHODS: We analyzed 1,240 pregnant women from the Spanish INMA [Environment and Childhood Project (INfancia y Medio Ambiente)] birth cohort study (recruitment period: 2003-2008) with measured first pregnancy trimester plasma concentrations of four PFASs (in nanograms/milliliter)...
November 13, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29133180/exposure-to-perfluoroalkyl-substances-during-pregnancy-and-child-behaviour-at-5-to-9years-of-age
#6
Birgit Bjerre Høyer, Jens Peter Bonde, Sandra Søgaard Tøttenborg, Cecilia Høst Ramlau-Hansen, Christian Lindh, Henning Sloth Pedersen, Gunnar Toft
We examined associations between prenatal exposure to perfluorohexane sulfonic acid (PFHxS), perfluoroheptanoic acid (PFHpA), perfluorononanoic acid (PFNA), and perfluorodecanic acid (PFDA) - and child behaviour (SDQ-total) and hyperactivity (sub-scale) at 5-9years of age in birth cohorts from Greenland and Ukraine. Pregnancy serum samples (N=1023) were analysed for perfluoroalkyl substances (PFASs) and categorized into tertiles and also used as continuous exposure variables. Problem behaviour and hyperactivity were assessed, using the Strength and Difficulties Questionnaire (SDQ) and categorized as normal/borderline and abnormal...
November 10, 2017: Hormones and Behavior
https://www.readbyqxmd.com/read/29128989/infant-mortality-lessons-learned-from-a-fetal-and-infant-mortality-review-program
#7
Haywood L Brown, Mark Smith, Yvonne Beasley, Teri Conard, Anne Lise Musselman, Virginia A Caine
Objective To review fetal and infant deaths from women enrolled in Indianapolis Healthy Start using the National Fetal and Infant Mortality Review (FIMR) methods to provide strategies for prevention. METHODS: Marion County Public Health Department (MCPHD) FIMR staff identified and reviewed 22 fetal and infant deaths to Indianapolis Healthy Start program participants between 2005 and 2012. Trained FIMR nurses completed 13 of 20 maternal interviews and compiled case summaries of all deaths from the MCPHD FIMR database...
November 11, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/29124444/risk-factors-for-unplanned-pregnancy-in-women-with-mental-illness-living-in-a-developing-country
#8
Elsa du Toit, Esme Jordaan, Dana Niehaus, Liezl Koen, Jukka Leppanen
Pregnant women in general are at an increased risk of experiencing symptoms of mental illness, and those living in a developing country are even more vulnerable. Research points towards a causal relationship between unplanned pregnancy and perinatal mental illness and suggests that pregnancy planning can aid in reducing the negative impact of mental illness on a woman, her unborn baby, and the rest of the family. In this quantitative, descriptive study, we investigated both socio-demographic factors and variables relating to mental illness itself that may place women at an increased risk of experiencing unplanned pregnancy...
November 9, 2017: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/29117931/electronic-brief-intervention-and-text-messaging-for-marijuana-use-during-pregnancy-initial-acceptability-of-patients-and-providers
#9
Justin Gray, Jessica R Beatty, Dace S Svikis, Karoline S Puder, Ken Resnicow, Janine Konkel, Shetoya Rice, Lucy McGoron, Steven J Ondersma
BACKGROUND: Marijuana is the most widely used illicit substance during pregnancy. Technology-delivered brief interventions and text messaging have shown promise in general and pregnant samples but have not yet been applied to marijuana use in pregnancy. OBJECTIVE: The objective of the study was to evaluate, among pregnant women and prenatal care providers, the acceptability of an electronic brief intervention and text messaging plan for marijuana use in pregnancy...
November 8, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29100171/the-danger-of-being-inattentive%C3%A2-%C3%A2-adhd-symptoms-and-risky-sexual-behaviour-in-russian-adolescents
#10
J Isaksson, A Stickley, R Koposov, V Ruchkin
BACKGROUND: Prior research has indicated that attention-deficit/hyperactivity disorder (ADHD) symptoms may be associated with an increased likelihood of engaging in risky sexual behaviour (RSB). However, research on this association among adolescents has been comparatively limited and mainly confined to North America. The aim of this study was to examine if inattention and hyperactivity/impulsivity symptoms were linked to RSB in a community cohort sample of Russian adolescents. METHODS: The study was based on a group of 537 adolescents from Northern Russia...
September 28, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/29070078/prevalence-of-prenatal-exposure-to-substances-of-abuse-questionnaire-versus-biomarkers
#11
REVIEW
Antonella Chiandetti, Gimena Hernandez, María Mercadal-Hally, Airam Alvarez, Vicente Andreu-Fernandez, Elisabet Navarro-Tapia, Adriana Bastons-Compta, Oscar Garcia-Algar
Alcohol and drugs of abuse consumption in young adults, including women of childbearing age, has experienced significant increase over the past two decades. The use of questionnaires as the only measure to investigate prenatal alcohol and drugs of abuse exposure underestimates the real prevalence of exposure and could mislead to wrong conclusions. Therefore, the aim of this article was to compare reported rates of prenatal alcohol and drugs of abuse consumption with biomarkers of exposure by a comprehensive review of the available literature...
October 25, 2017: Reproductive Health
https://www.readbyqxmd.com/read/29063150/drug-safety-in-pregnancy-the-german-embryotox-institute
#12
Katarina Dathe, Christof Schaefer
Since 1988, the German Embryotox institute combines individual counselling of pregnant women and their health care providers (HCP) with research on drug safety in pregnancy. In addition, Embryotox offers web-based information which covers the most important and most frequently requested pharmaceutical substances. In contrast to ready-made drug risk information in package leaflets and other product information, individual counselling considers different clinical settings such as (1) looking for a drug of choice or planning pregnancy under medication, (2) risk assessment of a particular drug that has already been taken during an (unplanned) pregnancy and (3) evaluation of an adverse pregnancy outcome in association with a particular medication...
October 24, 2017: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29057459/phone-calls-to-an-australian-pregnancy-and-lactation-counselling-service-regarding-use-of-galactagogues-during-lactation-the-mothersafe-experience
#13
Luke E Grzeskowiak, Majella Hill, Debra S Kennedy
Galactagogues represent substances used to enhance breast milk production. Between 2001 and 2014 we identified 2034 phone calls regarding the use of galactagogues made to MotherSafe. The majority involved discussion of domperidone (n = 1884; 92.6%), with the remainder relating to metoclopramide (n = 153; 7.5%) or other herbal galactagogues (eg fenugreek, milk thistle; n = 262; 12.9%). A 50% decrease in total calls occurred from 2011 to 2014, while the percentage of calls regarding herbal galactagogues increased from 0% in 2001 to 23% in 2014...
October 23, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29055046/an-assessment-of-depression-psychosocial-factors-and-resilience-among-women-seeking-prenatal-care-at-an-urban-community-health-center
#14
Katherine M Johnson, Frances M Paley, Anna M Modest, Michele R Hacker, Sabine Shaughnessy, Hope A Ricciotti, Jennifer Scott
OBJECTIVE: To describe the relationship between resilience and mental health and psychosocial characteristics in the prenatal period. METHODS: A prospective cohort pilot study was conducted among English-speaking women aged 18 years or older with singleton pregnancies of at least 20 weeks' duration who received prenatal care at an urban community health center in the USA between March and October 2014. Surveys were administered and a retrospective chart review was conducted...
October 20, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29050752/maternal-substance-use-disorders-and-infant-outcomes-in-the-first-year-of-life-among-massachusetts-singletons-2003-2010
#15
Sunah S Hwang, Hafsatou Diop, Chia-Ling Liu, Qi Yu, Hermik Babakhanlou-Chase, Xiaohui Cui, Milton Kotelchuck
OBJECTIVE: To determine the association of maternal substance use disorders (SUDs) during pregnancy with adverse neonatal outcomes and infant hospital re-admissions, observational stays, and emergency department utilization in the first year of life. STUDY DESIGN: We analyzed 2 linked statewide datasets from 2002 to 2010: the Massachusetts Pregnancy to Early Life Longitudinal data system and the Massachusetts Bureau of Substance Abuse Services Management Information System...
October 16, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/29040165/dating-violence-against-hiv-infected-youth-in-south-africa-associations-with-sexual-risk-behavior-medication-adherence-and-mental-health
#16
Rachel Kidman, Avy Violari
BACKGROUND: As perinatal HIV-infected youth become sexually active, the potential for onward transmission becomes an increasing concern. In other populations, intimate partner violence (IPV) is a risk factor for HIV acquisition. We build on this critical work by studying the role of IPV in facilitating onward transmission among HIV-infected youth - an important step towards effective intervention. SETTING: Soweto, South Africa. METHODS: Self-report surveys were completed by 129 perinatal HIV-infected female youth (aged 13-24)...
October 14, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/29039230/effect-of-prenatal-waterpipe-tobacco-smoke-on-airway-inflammation-in-murine-model-of-asthma-of-adult-offspring-mice
#17
Nour A Al-Sawalha, Hanadi F Al-Bo'ul, Karem H Alzoubi, Omar F Khabour, Vaidehi J Thanawala
OBJECTIVE: Worldwide popularity of waterpipe tobacco smoking has increased, including in pregnant women. This study investigates the effect of prenatal waterpipe tobacco smoke (WTS) exposure on airway inflammation in a murine model of asthma of adult offspring mice. MATERIALS AND METHODS: Pregnant BALB/c mice were exposed to fresh air or WTS, using a whole-body exposure system that mimics human use during WTS. Adult male offspring mice were divided into; (1) control (prenatal fresh air, postnatal ovalbumin sensitization and saline challenge), (2) postnatal Ova S/C (prenatal fresh air, postnatal ovalbumin sensitization and challenge (Ova S/C)), (3) prenatal WTS (prenatal WTS, postnatal ovalbumin sensitization and saline challenge) and (4) prenatal WTS + postnatal Ova S/C...
July 2017: Inhalation Toxicology
https://www.readbyqxmd.com/read/29025051/integrating-behavioral-health-risk-assessment-into-centralized-intake-for-maternal-and-child-health-services
#18
Sarah Kye Price, D Crystal Coles, Tracey Wingold
Effectively promoting women's health during and around the time of pregnancy requires early, nonstigmatizing identification and assessment of behavioral health risks (such as depression, substance use, smoking, and interpersonal violence) combined with timely linkage to community support and specialized interventions. This article describes an integrated approach to behavioral health risk screening woven into a point of first contact with the health care delivery system: centralized intake for maternal and child health home visiting programs...
September 4, 2017: Health & Social Work
https://www.readbyqxmd.com/read/28986209/effects-of-prenatal-alcohol-exposure-in-a-prospective-sample-of-young-adults-mental-health-substance-use-and-difficulties-with-the-legal-system
#19
Mary Ellen Lynch, Julie A Kable, Claire D Coles
INTRODUCTION: Few studies have focused on the transition to adulthood in adults with prenatal alcohol exposure (PAE). In this study, we examine the occurrence of problem behavior at this transition, including mental health problems, substance use, and difficulties with the legal system. The sample is prospective and provides an opportunity to examine effects of a wide range of prenatal exposure. Adults with PAE were expected to show more problem behavior; the impact of level of exposure was examined as well...
October 3, 2017: Neurotoxicology and Teratology
https://www.readbyqxmd.com/read/28985919/contributing-factors-of-teenage-pregnancy-among-african-american-females-living-in-economically-disadvantaged-communities
#20
Lauren Summers, Young-Me Lee, Hyeonkyeong Lee
AIM: To identify contributing factors that increased the risk of pregnancy among African-American adolescent females living in economically disadvantaged communities and to evaluate the current pregnancy prevention programs addressing these factors in order to provide suggestions for the development of tailored pregnancy prevention programs for this target population. BACKGROUND: Pregnancy rates among adolescents in the United States have declined over the past several years...
October 2017: Applied Nursing Research: ANR
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