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substance use in pregnancy

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https://www.readbyqxmd.com/read/29767826/accidental-or-intentional-exposure-to-potentially-toxic-medications-natural-toxins-and-chemicals-during-pregnancy-analysis-of-data-from-tox-info-suisse
#1
Tabea Vogel, Saskia Lüde, Rahel Baumgartner, Christine Rauber-Lüthy, Ana Paula Simões-Wüst
OBJECTIVE: Affected women and health professionals are still often unsure about how to react to exposures to potentially harmful agents during pregnancy. We wanted to find out which agents worry both pregnant women and professionals, under what circumstances the exposures take place, how they are currently dealt with and how serious they are. METHODS: Making use of the archives of Tox Info Suisse, the foundation that provides poisons information in Switzerland both for members of the general public and for healthcare professionals, we set up an analysis of exposures to possibly harmful agents during pregnancy...
May 16, 2018: Swiss Medical Weekly
https://www.readbyqxmd.com/read/29762274/decomposing-medicaid-spending-during-health-system-reform-and-aca-expansion-evidence-from-oregon
#2
Stephanie Renfro, Stephan Lindner, K John McConnell
BACKGROUND: Expansion of the Medicaid program is likely to create new budgetary pressures at the state and federal levels, creating a need for greater understanding of how program dollars are allocated and what drives spending growth. OBJECTIVE: To characterize Oregon Medicaid expenditures across diseases and medical conditions, during periods of payment reform and coverage expansion. RESEARCH DESIGN: Decomposition of changes in Medicaid expenditures using a person-based allocation of spending across 50 diseases/medical conditions...
May 12, 2018: Medical Care
https://www.readbyqxmd.com/read/29760859/substance-use-in-pregnant-women-using-the-emergency-department-undertested-and-overlooked
#3
C Leigh Moyer, Sean Johnson, Marilyn G Klug, Larry Burd
Introduction: The objective was to determine if pregnant women visiting the emergency department (ED) are tested for substance use as frequently as non-pregnant women. Methods: We captured all ED visits over a six-year period (2010-2016) from a single community hospital and identified women of childbearing age, defined for our study as 11-50 years old. We collected demographic data including age in years, ethnicity, body mass index, marital status, disposition, last encounter department, method of arrival, and day of week...
May 2018: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29760680/disruption-in-thyroid-signaling-pathway-a-mechanism-for-the-effect-of-endocrine-disrupting-chemicals-on-child-neurodevelopment
#4
REVIEW
Akhgar Ghassabian, Leonardo Trasande
Thyroid hormones are crucial in normal brain development. Transient and mild thyroid hormone insufficiency in pregnancy is also associated with impaired neurodevelopment in the offspring (e.g., 3-4 IQ score loss in association with maternal free thyroxine in the lowest fifth percentile). While inadequate iodine intake remains the most common underlying cause of mild thyroid hormone insufficiency in vulnerable populations including pregnant women, other factors such as exposure to environmental contaminants have recently attracted increasing attention, in particular in interaction with iodine deficiency...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29758015/determinants-and-temporal-trends-of-perfluoroalkyl-substances-in-pregnant-women-the-hokkaido-study-on-environment-and-children-s-health
#5
Meng-Shan Tsai, Chihiro Miyashita, Atsuko Araki, Sachiko Itoh, Yu Ait Bamai, Houman Goudarzi, Emiko Okada, Ikuko Kashino, Hideyuki Matsuura, Reiko Kishi
Perfluoroalkyl substances (PFAS) are persistent bio-accumulative chemicals that impact the health of pregnant women and their children. PFAS derive from environmental and consumer products, which depend on human lifestyle, socioeconomic characteristics, and time variation. Here, we aimed to explore the temporal trends of PFAS in pregnant women and the characteristics related to maternal PFAS concentration. Our study is part of the Hokkaido Study on Environment and Children's Health, the Hokkaido large-scale cohort that recruited pregnant women between 2003 and 2011...
May 14, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29749666/adverse-adult-consequences-of-different-alcohol-use-patterns-in-adolescence-an-integrative-analysis-of-data-to-age-30-years-from-four-australasian-cohorts
#6
Edmund Silins, L John Horwood, Jake M Najman, George C Patton, John W Toumbourou, Craig A Olsson, Delyse M Hutchinson, Louisa Degenhardt, David Fergusson, Denise Becker, Joseph M Boden, Rohan Borschmann, Maria Plotnikova, George J Youssef, Robert J Tait, Philip Clare, Wayne D Hall, Richard P Mattick
BACKGROUND AND AIMS: Studies have linked adolescent alcohol use with adverse consequences in adulthood; yet it is unclear how strong the associations are and to what extent they may be due to confounding. Our aim was to estimate the strength of association between different patterns of adolescent drinking and longer-term psychosocial harms taking into account individual, family, and peer factors. DESIGN: Participant-level data were integrated from four long running longitudinal studies: Australian Temperament Project; Christchurch Health and Development Study; Mater Hospital and University of Queensland Study of Pregnancy; Victorian Adolescent Health Cohort Study...
May 10, 2018: Addiction
https://www.readbyqxmd.com/read/29736274/burden-of-physical-psychological-and-social-ill-health-during-and-after-pregnancy-among-women-in-india-pakistan-kenya-and-malawi
#7
Mary McCauley, Barbara Madaj, Sarah A White, Fiona Dickinson, Sarah Bar-Zev, Mamuda Aminu, Pamela Godia, Pratima Mittal, Shamsa Zafar, Nynke van den Broek
Introduction: For every woman who dies during pregnancy and childbirth, many more suffer ill-health, the burden of which is highest in low-resource settings. We sought to assess the extent and types of maternal morbidity. Methods: Descriptive observational cross-sectional study at primary-level and secondary-level healthcare facilities in India, Pakistan, Kenya and Malawi to assess physical, psychological and social morbidity during and after pregnancy. Sociodemographic factors, education, socioeconomic status (SES), quality of life, satisfaction with health, reported symptoms, clinical examination and laboratory investigations were assessed...
2018: BMJ Global Health
https://www.readbyqxmd.com/read/29734025/variability-and-predictors-of-serum-perfluoroalkyl-substance-concentrations-during-pregnancy-and-early-childhood
#8
Samantha L Kingsley, Melissa N Eliot, Karl T Kelsey, Antonia M Calafat, Shelley Ehrlich, Bruce P Lanphear, Aimin Chen, Joseph M Braun
Exposure to poly- and perfluoroalkyl substances (PFAS), ubiquitous and persistent environmental contaminants, could be associated with adverse health outcomes, but there are limited longitudinal data assessing patterns and predictors of exposure during childhood. We quantified concentrations of eight different PFAS in sera collected from women during pregnancy and children at delivery and ages 3 and 8 years in 367 mother-child pairs enrolled in a prospective cohort from 2003 to 2006. In general, median childhood PFAS concentrations increased from birth to age 3 and then decreased by age 8...
May 4, 2018: Environmental Research
https://www.readbyqxmd.com/read/29727701/prenatal-exposure-to-tobacco-and-cannabis-effects-on-autonomic-and-emotion-regulation
#9
Rina D Eiden, Pamela Schuetze, Shannon Shisler, Marilyn A Huestis
Tobacco and cannabis are often used together in pregnancy and both have effects on children's regulatory system. Yet, little is known about the impact of co-use on the development of emotion regulation at the developmentally salient age of 2 years. One pathway linking co-exposure to tobacco and cannabis to toddler regulation may be via poor autonomic regulation in infancy. In addition, substance using mothers may be more dysregulated themselves, which may have direct effects on toddler regulation, but may also affect parenting, particularly maternal sensitivity during mother-child interactions...
May 1, 2018: Neurotoxicology and Teratology
https://www.readbyqxmd.com/read/29720114/adverse-obstetric-and-neonatal-outcomes-complicated-by-psychosis-among-pregnant-women-in-the-united-states
#10
Qiu-Yue Zhong, Bizu Gelaye, Gregory L Fricchione, Paul Avillach, Elizabeth W Karlson, Michelle A Williams
BACKGROUND: Adverse obstetric and neonatal outcomes among women with psychosis, particularly affective psychosis, has rarely been studied at the population level. We aimed to assess the risk of adverse obstetric and neonatal outcomes among women with psychosis (schizophrenia, affective psychosis, and other psychoses). METHODS: From the 2007 - 2012 National (Nationwide) Inpatient Sample, 23,507,597 delivery hospitalizations were identified. From the same hospitalization, International Classification of Diseases diagnosis codes were used to identify maternal psychosis and outcomes...
May 2, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29705692/prenatal-and-childhood-exposure-to-per-and-polyfluoroalkyl-substances-pfass-and-child-cognition
#11
Maria H Harris, Emily Oken, Sheryl L Rifas-Shiman, Antonia M Calafat, Xiaoyun Ye, David C Bellinger, Thomas F Webster, Roberta F White, Sharon K Sagiv
BACKGROUND: Per- and polyfluoroalkyl substances (PFASs) are suspected developmental toxicants, but epidemiological evidence on neurodevelopmental effects of PFAS exposure is inconsistent. We examined associations of prenatal and childhood PFAS exposure with performance on assessments of cognition in children. METHODS: We included mother-child pairs from Project Viva, a longitudinal Boston-area birth cohort enrolled during 1999-2002. We quantified concentrations of eight PFASs, including perfluorooctane sulfonate (PFOS), perfluorooctanoate (PFOA), and perfluorohexane sulfonate (PFHxS), in plasma collected from women during pregnancy (median 9...
April 26, 2018: Environment International
https://www.readbyqxmd.com/read/29704852/prevalence-of-alcohol-use-in-pregnant-women-with-substance-use-disorder
#12
Ludmila N Bakhireva, Shikhar Shrestha, Laura Garrison, Lawrence Leeman, William F Rayburn, Julia M Stephen
BACKGROUND: Prenatal care programs for women with opioid use disorder (OUD) often focus treatment/counseling plans around illicit substances, while concurrent use of alcohol might present an equal or greater risk to the fetus. METHODS: This study evaluated self-reported prevalence of alcohol use in patients participating in a comprehensive prenatal care program for women with substance use disorder (SUD; n = 295), of which 95% are treated for OUD, and pregnant women being served through general obstetrical clinics at the University of New Mexico (n = 365)...
June 1, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29701148/quantification-of-methamphetamine-%C3%A2-shabu%C3%A2-in-biological-matrices-to-detect-prenatal-exposure-a-case-report-and-a-literature-review
#13
Pilar Jarque, Antonia Roca, Isabel Gomila, Valeria Noce, B Bernardino Barcelo, Julia Klein
BACKGROUND: Methamphetamine misuse represents an increasing global public health problem. Its consumption during pregnancy becomes a relevant issue, since it has clinical consequences for the child's health and the pregnant woman. Despite this, there are only few data in the literature that include analytical results in the matrices used to detect prenatal exposure. OBJECTIVES: 1) Present a case report of prenatal methamphetamine exposure with toxicological analytical confirmation in biological matrices; and 2) Perform a compilation of prenatal methamphetamine exposure studies and case reports which include toxicological analytical results...
April 26, 2018: Current Pharmaceutical Biotechnology
https://www.readbyqxmd.com/read/29692634/chronic-pain-during-pregnancy-a-review-of-the-literature
#14
REVIEW
Shona L Ray-Griffith, Michael P Wendel, Zachary N Stowe, Everett F Magann
Background and purpose: The majority of the reviews and studies on chronic pain in pregnancy have primarily focused on the pharmacological and non-pharmacological treatment options. The purpose of our review was to identify evidence-based clinical research for the evaluation and management of preexisting chronic pain in pregnancy, chronic pain associated with pregnancy, and chronic pain in relation to mode of delivery. Methods: A literature search was undertaken using the search engines PubMed, CINAHL, EBSCOhost, and Web of Science...
2018: International Journal of Women's Health
https://www.readbyqxmd.com/read/29679105/the-practices-of-french-general-practitioners-regarding-screening-and-counselling-pregnant-women-for-tobacco-smoking-and-alcohol-drinking
#15
Raphaël Andler, Chloé Cogordan, Anne Pasquereau, Jean-François Buyck, Viêt Nguyen-Thanh
OBJECTIVES: Our study aims to describe French general practitioners' (GPs') practices toward pregnant patients regarding alcohol consumption and smoking and to highlight factors associated with specific practices. METHODS: In 2015, a representative sample of 1414 French GPs completed a telephone survey based on a stratified random sampling. RESULTS: 61% of GPs declared screening for alcohol use and 82% for smoking at least once with each pregnant patient; quitting was not systematically advised either for alcohol or for smoking...
April 20, 2018: International Journal of Public Health
https://www.readbyqxmd.com/read/29676338/psychoactive-substance-use-and-psychiatric-morbidity-among-pregnant-women-attending-an-ante-natal-clinic-in-benin-city-nigeria
#16
Oluyemisi O Adebowale, Bawo O James
Objective: This study sought to determine the prevalence, patterns and feasibility of screening for psychoactive substance use among pregnant women in an antenatal clinic in Nigeria. It also aimed to determine the relationship between psychoactive substance use risk severity and psychiatric morbidity. Methods: A cross-sectional study was undertaken among 395 pregnant women previously booked for ante-natal care. A sociodemographic questionnaire, the Alcohol Smoking and Substance Involvement Test (ASSIST) and the 20-item self-reporting questionnaire-20 were interviewer administered...
January 2018: Nigerian Postgraduate Medical Journal
https://www.readbyqxmd.com/read/29672868/fetal-cerebral-circulation-as-target-of-maternal-alcohol-consumption
#17
Anna N Bukiya, Alex M Dopico
Alcohol (ethanol) is one of the most widely used psychoactive substances worldwide. Alcohol consumption during pregnancy may result in a wide range of morphological and neurodevelopmental abnormalities termed fetal alcohol spectrum disorders (FASD), with the most severe cases diagnosed as fetal alcohol syndrome (FAS). FAS and FASD are not readily curable and currently represent the leading preventable causes of birth defect and neurodevelopmental delay in the US. The etiology of FAS/FASD remains poorly understood...
April 19, 2018: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29672143/adolescent-age-of-sexual-initiation-and-subsequent-adult-health-outcomes
#18
Marina Epstein, Madeline Furlong, Rick Kosterman, Jennifer A Bailey, Kevin M King, Sara A Vasilenko, Christine M Steeger, Karl G Hill
OBJECTIVES: To examine the mechanisms of the association between age of sexual initiation and adult health. METHODS: Data from the Seattle Social Development Project (n = 808), in Seattle, Washington, included outcomes when participants were in their 30s (2005-2014): substance use disorders, depression, poor health, and obesity. Sexual consequence mediators included sexually transmitted infection, adolescent pregnancy, and a high number of sexual partners. We used linear logistic regression to model main effect and mediated associations...
April 19, 2018: American Journal of Public Health
https://www.readbyqxmd.com/read/29671666/psychiatric-admission-during-pregnancy-in-women-with-schizophrenia-who-attended-a-specialist-antenatal-clinic
#19
Elly Lorraine Harris, Jacqueline Frayne, Suzanna Allen, Kanni Renganathan, Thinh Ngoc Nguyen
OBJECTIVES: The mental health and wellbeing of pregnant women with schizophrenia is an area of research interest. We aim to explore this relationship particularly in regards to psychiatric admission rates, timing and their associated contributing factors. METHODS: A total of 98 pregnancies to women with schizophrenia, who attended a specialist antenatal clinic and delivered from July 2007 to February 2016, were retrospectively examined. The cohort was divided into two groups based on psychiatric admission...
April 19, 2018: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29651928/rural-postpartum-women-with-substance-use-disorders
#20
Debra Kramlich, Rebecca Kronk, Lenora Marcellus, Alison Colbert, Karen Jakub
The incidence of perinatal opioid use and neonatal withdrawal continues to rise rapidly in the face of the growing opioid addiction epidemic in the United States, with rural areas more severely affected. Despite decades of research and development of practice guidelines, maternal and neonatal outcomes have not improved substantially. This focused ethnography sought to understand the experience of accessing care necessary for substance use disorder recovery, pregnancy, and parenting. Personal accounts of 13 rural women, supplemented by participant observation and media artifacts, uncovered three domains with underlying themes: challenges of getting treatment and care (service availability, distance/geographic location, transportation, provider collaboration/coordination, physical and emotional safety), opportunities to bond (proximity, information), and importance of relationships (respect, empathy, familiarity, inclusion, interactions with care providers)...
April 1, 2018: Qualitative Health Research
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