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Vestibular therapy

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https://www.readbyqxmd.com/read/29594074/effect-of-early-vestibular-rehabilitation-on-vertigo-and-unsteadiness-in-patients-with-acute-and-sub-acute-head-trauma
#1
Sadegh Jafarzadeh, Akram Pourbakht, Eshagh Bahrami, Shohreh Jalaie, Arash Bayat
Introduction: Vestibular rehabilitation is a treatment option for the management of vertigo and unsteadiness, which are very common in head trauma patients and more challenging in the early months after trauma. This study evaluated the effectiveness of a vestibular rehabilitation program in the recovery of acute and sub-acute head trauma patients. The goal of this study was evaluation of the effect of early vestibular rehabilitation on patients with acute and sub-acute head trauma. Materials and Methods: This study was performed in 20 head trauma patients with vertigo and unsteadiness...
March 2018: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/29574462/remote-limb-ischemic-preconditioning-attenuates-cerebrovascular-depression-during-sinusoidal-galvanic-vestibular-stimulation-via-%C3%AE-1-adrenoceptor-protein-kinase-c%C3%AE%C2%B5-endothelial-no-synthase-pathway-in-rats
#2
Devin W McBride, Cesar Reis, John H Zhang, Richard Applegate, Jiping Tang
BACKGROUND: Vasovagal syncope (VVS) is characterized by hypotension and bradycardia followed by lowering of cerebral blood flow. Remote limb ischemic preconditioning (RIPC) is well documented to provide cardio- and neuroprotection as well as to improve cerebral blood flow. We hypothesized that RIPC will provide protection against VVS-induced hypotension, bradycardia, and cerebral hypoperfusion. Second, because endothelial nitric oxide synthase has been reported as a mediator of cerebral blood flow control, we hypothesized that the mechanism by which RIPC primes the vasculature against VVS is via the α1 -adrenoceptor-protein kinase Cε-endothelial nitric oxide synthase pathway...
March 24, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29573626/effects-of-combined-oral-contraception-containing-drospirenone-on-premenstrual-exacerbation-of-meniere-s-disease-preliminary-study
#3
Salvatore Caruso, Diletta Mauro, Luigi Maiolino, Caterina Grillo, Agnese Maria Chiara Rapisarda, Stefano Cianci
OBJECTIVES: Meniere's disease is caused by an augmented endolymph pressure in the inner ear; symptoms are vertigo, fluctuating hearing loss and tinnitus. Exacerbations has been noted during premenstrual phase. The study aims to evaluate the effects of a 20 μm Ethinylestradiol (EE) and 3 mg Drospirenone (DRSP) oral contraceptive (20 μmEE/3mgDRSP) in continuous regimen, associated with rehabilitation therapy on Meniere's disease. STUDY DESIGN: This non-randomized controlled study was performed from October 2015 to October 2017...
March 10, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29568697/intratympanic-it-therapies-for-meni%C3%A3-re-s-disease-some-consensus-among-the-confusion
#4
Desi P Schoo, Grace X Tan, Matthew R Ehrenburg, Seth E Pross, Bryan K Ward, John P Carey
Purpose of Review: Aminoglycosides and corticosteroids are commonly used to treat Menière's disease. Intratympanic (IT) administration of these medications allows high inner ear concentrations without significant adverse systemic effects. As a direct result, IT therapy has grown in popularity. Recent studies have compared patient outcomes between IT aminoglycosides and corticosteroids. This review summarizes these findings. Recent Findings: Trials comparing IT corticosteroids to IT placebo or oral therapy have had conflicting results...
June 2017: Current Otorhinolaryngology Reports
https://www.readbyqxmd.com/read/29559247/cox-2-as-a-determinant-of-lower-disease-free-survival-for-patients-affected-by-ameloblastoma
#5
Marco Aurélio Petroni Montezuma, Felipe Paiva Fonseca, Bernar Monteiro Benites, Ciro Dantas Soares, Gleyson Kleber do Amaral-Silva, Oslei Paes de Almeida, Fernando Augusto Soares, Rosana Lima Pagano, Eduardo Rodrigues Fregnani
Ameloblastoma is a locally aggressive neoplasm with a poorly understood pathogenesis. Therefore, the aim of this study is to investigate whether COX-2 expression is associated with ameloblastoma microvascular density (MVD) and with tumor aggressiveness. Sixty-three cases of primary ameloblastomas arranged in tissue microarray were submitted to immunohistochemistry against cyclooxigenase-2 (COX-2) and CD34. Clinicopathological parameters regarding sex, age, tumour size, tumour duration, tumour location, treatment, recurrences, radiographic features, vestibular/lingual and basal cortical disruption and follow-up data were obtained from patients' medical records and correlated with the proteins expression...
March 15, 2018: Pathology, Research and Practice
https://www.readbyqxmd.com/read/29557843/a-xenograft-model-of-vestibular-schwannoma-and-hearing-loss
#6
Christine T Dinh, Olena Bracho, Christine Mei, Esperanza Bas, Cristina Fernandez-Valle, Fred Telischi, Xue-Zhong Liu
HYPOTHESIS: Microsurgical implantation of mouse merlin-deficient Schwann cells (MD-SC) into the cerebellopontine angle of immunodeficient rats will initiate tumor formation, hearing loss, and vestibular dysfunction. BACKGROUND: The progress in identifying effective drug therapies for treatment of Neurofibromatosis type II (NF2) is limited by the availability of animal models of VS that develop hearing loss and imbalance. METHODS: A microsurgical technique for implanting MD-SCs onto the cochleovestibular nerve of rats was developed...
March 19, 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29546771/newly-diagnosed-meniere-s-disease-clinical-course-with-initiation-of-noninvasive-treatment-including-an-accounting-of-vestibular-migraine
#7
Firas Sbeih, Florian Christov, Michael B Gluth
OBJECTIVE: To describe the course of Meniere's disease with noninvasive treatment during the first few years after initial diagnosis. METHODS: A retrospective review of consecutive patients with newly diagnosed definite Meniere's disease between 2013 and 2016 and a minimum follow-up of 1 year. Patients received a written plan for low sodium, water therapy, and treatment with a diuretic and/or betahistine. Subjects were screened and treated for vestibular migraine as needed...
March 1, 2018: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/29546707/generation-and-use-of-merlin-deficient-human-schwann-cells-for-a-high-throughput-chemical-genomics-screening-assay
#8
Alejandra M Petrilli, Cristina Fernández-Valle
Schwannomas are benign nerve tumors that occur sporadically in the general population and in those with neurofibromatosis type 2 (NF2), a tumor predisposition genetic disorder. NF2-associated schwannomas and most sporadic schwannomas are caused by inactivating mutations in Schwann cells in the neurofibromatosis type 2 gene (NF2) that encodes the merlin tumor suppressor. Despite their benign nature, schwannomas and especially vestibular schwannomas cause considerable morbidity. The primary available therapies are surgery or radiosurgery which usually lead to loss of function of the compromised nerve...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29534265/-retinal-astrocytic-hamartoma-in-neurofibromatosis-type-2-metaanalysis-and-a-case-report
#9
Daniela Aneta Starosta, Birgit Lorenz
BACKGROUND: Neurofibromatosis type 2 (NF2) is a genetic condition with an autosomal dominant pattern of inheritance and incomplete penetrance. It is characterized by multiple benign tumors of the central and peripheral nervous system including astrocytomas, ependymomas, meningeomas, and schwannomas, among which bilateral vestibular schwannomas are the most frequent. Among ocular manifestations of NF2, juvenile subcapsular cataract is the most common followed by epiretinal membranes and combined hamartomas of the retina and retinal pigment epithelium...
March 2018: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/29533717/does-the-use-of-a-walking-bleaching-technique-increase-bone-resorption-markers
#10
C Bersezio, P Vildósola, M Sáez, F Sánchez, R Vernal, O B Oliveira, G Jorquera, J Basualdo, A Loguercio, E Fernández
OBJECTIVE: This randomized clinical trial evaluated the effect of 35% hydrogen peroxide in comparison with 37% carbamide peroxide in a nonvital bleaching technique of "walking bleaching" (four sessions of treatment) on periodontal markers: nuclear factor kappa B-ligand (RANK-L-process of root resorption marker) and interleukin 1β (IL-1β-inflammatory response marker). METHODS AND MATERIALS: Fifty volunteers presenting with discoloration of nonvital teeth and endodontic treatment in good condition participated...
March 13, 2018: Operative Dentistry
https://www.readbyqxmd.com/read/29531877/a-suspected-vestibular-schwannoma-with-uncharacteristic-growth-dynamic-and-symptom-severity-a-case-report
#11
Felix Ehret, Alexander Muacevic
Vestibular schwannomas are mostly sporadic, neuroectodermal, benign tumors of the myelin-forming cells of the vestibulocochlear nerve. Typical initial symptoms of vestibular schwannomas often include unilateral hearing loss, tinnitus, vertigo, and headaches. As schwannomas characteristically show a slow growth rate and various symptoms, different therapeutic approaches are possible, ranging from a watchful waiting strategy to radiation therapy and neurosurgical tumor removal. In addition, these treatment options should be evaluated carefully and assigned individually to the patients' needs and symptoms while respecting the feasibility and possible outcome of the chosen treatment...
January 5, 2018: Curēus
https://www.readbyqxmd.com/read/29515781/cxcr4-a-new-player-in-vestibular-schwannoma-pathogenesis
#12
Maria Breun, Alexandra Schwerdtfeger, Donato Daniel Martellotta, Almuth F Kessler, Jose M Perez, Camelia M Monoranu, Ralf-Ingo Ernestus, Cordula Matthies, Mario Löhr, Carsten Hagemann
Background: CXCR4 is a chemokine receptor that recruits blood stem cells and increases tumor cell growth and invasiveness. We examined CXCR4 expression in vestibular schwannomas (VS) from patients with and without neurofibromatosis type 2 (NF2) and correlated the levels with the patients' clinical characteristics. The aim was to determine whether CXCR4 can be used as a prognostic marker and as a target for systemic therapy. Results: Overall, CXCR4 mRNA levels were 4...
February 9, 2018: Oncotarget
https://www.readbyqxmd.com/read/29500503/-management-of-acute-vertigo-and-dizziness-patients-in-emergency-departments-in-germany
#13
J Löhler, D Eßer, B Wollenberg, L E Walther
BACKGROUND: Dizziness and vertigo are some of the most common reasons for seeking medical help. Acute dizziness and vertigo require interdisciplinary cooperation. New diagnostic methods (the video head impulse test) and modern algorithms (HINTS: head impulse test/nystagmus [direction changing]/test-of-skew) are increasingly used in case of the acute vestibular syndrome in emergency care. METHODS: In a survey on the management and participation of the ENT specialist area, the authors interviewed 168 German ENT clinics during the spring of 2017 using an online survey...
March 2, 2018: HNO
https://www.readbyqxmd.com/read/29490694/systematic-review-of-ototoxic-pre-surgical-antiseptic-preparations-what-is-the-evidence
#14
REVIEW
Shubhi Singh, Brian Blakley
OBJECTIVE: There is uncertainty regarding the safety of surgical antiseptic preparations in the ear. A systematic review of the literature was conducted to assess the evidence regarding ototoxicity of surgical antiseptic preparations. METHODS: A literature search was conducted using the PRISMA methods. Key words included "ototoxicity" "hearing loss", "antiseptic", "surgical preparation", "tympanoplasty", "vestibular dysfunction", "chlorhexidine", "iodine", "povidone", "ethanol", and "hydrogen peroxide" using Medline, Embase, Cochrane Library, Scopus and Web of Science...
March 1, 2018: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29488253/visual-problems-associated-with-traumatic-brain-injury
#15
REVIEW
Richard A Armstrong
Traumatic brain injury (TBI) and its associated concussion are major causes of disability and death. All ages can be affected but children, young adults and the elderly are particularly susceptible. A decline in mortality has resulted in many more individuals living with a disability caused by TBI including those affecting vision. This review describes: (1) the major clinical and pathological features of TBI; (2) the visual signs and symptoms associated with the disorder; and (3) discusses the assessment of quality of life and visual rehabilitation of the patient...
February 28, 2018: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/29487747/extranodal-non-b-non-t-cell-lymphoma-with-bilateral-tympanic-bulla-involvement-in-a-cat
#16
Austin T Kerns, Kelsey A Brakel, Christopher Premanandan, Ashlie Saffire, Sarah A Moore
Case summary: A 9-year-old spayed female domestic shorthair cat with clinical signs suggestive of chronic recurrent otitis media and recent seizures was presented with multifocal nervous system disease, including bilateral central and/or peripheral vestibular, cerebellar and forebrain deficits. Prior to presentation, there was inadequate improvement after 6 weeks of treatment for bilateral middle ear effusion from which a highly susceptible Staphylococcus species was cultured. This was followed by the development of seizures...
January 2018: JFMS Open Reports
https://www.readbyqxmd.com/read/29482202/predictive-factors-for-vestibular-loss-in-children-with-hearing-loss
#17
Kristen L Janky, Megan L A Thomas, Robin R High, Kendra K Schmid, Oluwaseye Ayoola Ogun
Purpose: The aim of this study was to determine if there are factors that can predict whether a child with hearing loss will also have vestibular loss. Method: A retrospective chart review was completed on 186 children with hearing loss seen at Boys Town National Research Hospital for vestibular testing from 1999 to 2015 through neurosensory genetics clinic or cochlear implant candidacy. Each child's medical chart was reviewed to obtain the following data: vestibular loss severity (classified as normal, bilateral, or mild to moderate), degree of hearing loss (bilateral pure-tone average [PTA]), imaging abnormalities (classified as "normal" or "abnormal"), parental concerns for gross motor delay (classified as "yes, there is concern" or "no, there is not a concern"), parent report of age when their child sat (months) and walked independently (months), comorbidities (classified as "yes" if there were 1 or more comorbidities or "no" if there were no comorbidities), and score on the Developmental Profile-3...
February 26, 2018: American Journal of Audiology
https://www.readbyqxmd.com/read/29473980/low-dose-t1w-dce-mri-for-early-time-points-perfusion-measurement-in-patients-with-intracranial-tumors-a-pilot-study-applying-the-microsphere-model-to-measure-absolute-cerebral-blood-flow
#18
Ka-Loh Li, Daniel Lewis, Alan Jackson, Sha Zhao, Xiaoping Zhu
BACKGROUND: Previous studies have measured cerebral blood flow (CBF) with DSC-MRI using an "early time points" (ET) method based on microsphere theory. PURPOSE: To develop and assess a new ET method for absolute CBF estimation using low-dose high-temporal (LDHT) T1W-DCE-MRI. STUDY TYPE: Retrospective cohort study. SUBJECTS: Seven patients with sporadic vestibular schwannoma (VS) who underwent test-retest imaging; one patient with glioblastoma multiforme (GBM) imaged pretreatment; and 12 neurofibromatosis type 2 (NF2) patients undergoing bevacizumab treatment, imaged pre- and 90 days posttreatment...
February 23, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29468616/does-focal-mechanical-stimulation-of-the-lower-limb-muscles-improve-postural-control-and-sit-to-stand-movement-in-elderly
#19
G Attanasio, F Camerota, M Ralli, G Galeoto, G La Torre, M Galli, M De Vincentiis, A Greco, Claudia Celletti
BACKGROUNDS: Imbalance in elderly is a common problem strictly related to fall. AIMS: This study investigates the possibility that a new protocol based on the focal mechanical muscle vibration may improve balance and stability in elderly. METHODS: Pre-post non-randomized clinical trial has been used. Patients referring postural disequilibrium with negative vestibular bed-side examinations have been treated with focal muscle vibration applied to quadriceps muscles and evaluated before and immediately after therapy and after 1 week and after 1 month with postural stabilometric examination and with an inertial measurement units during the time up and go test...
February 21, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29466539/management-of-recurrent-vestibular-neuritis-in-a-patient-treated-for-rheumatoid-arthritis
#20
Richard A Roberts
Purpose: This clinical report is presented to describe how results of vestibular function testing were considered along with other medical history to develop a management plan that was ultimately successful. Method: The patient underwent audio-vestibular assessment including comprehensive audiogram, videonystagmography, cervical vestibular evoked myogenic potential, and postural stability testing. Results: Results from initial testing were most consistent with uncompensated peripheral vestibular dysfunction affecting the right superior vestibular nerve...
March 8, 2018: American Journal of Audiology
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