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https://www.readbyqxmd.com/read/28107389/effect-of-axial-eye-length-on-retinal-vessel-parameters-in-6-to-12-year-old-malay-girls
#1
Evelyn Li Min Tai, Ling-Jun Li, Wan Hitam Wan-Hazabbah, Tien-Yin Wong, Ismail Shatriah
PURPOSE: Retinal vessel analysis is affected by both systemic and ocular factors. Malays are the major ethnicity in South East Asia. Data on the retinal microvasculature in Malays is limited, especially among children. We aim to evaluate the influence of ocular biometry on retinal vessel parameters in young Malay girls. METHODS: This was a cross-sectional, hospital-based study involving 86 Malay girls aged 6 to 12 years old in Hospital Universiti Sains Malaysia from 2015-2016...
2017: PloS One
https://www.readbyqxmd.com/read/28107326/identifying-malnutrition-nutritional-status-in-newly-diagnosed-patients-with-cancer%C3%A2
#2
Karthikayini Krishnasamy, Tang Li Yoong, Chong Mei Chan, Lau Peng Chong, Karuthan Chinna
BACKGROUND: Malnutrition is common among patients with cancer, but little attention is given to its risks and consequences.
. OBJECTIVES: The aim of this study is to assess the nutritional status and identify the factors associated with malnutrition among newly diagnosed patients with cancer
. METHODS: Patients admitted with newly diagnosed cancer at a teaching hospital in Malaysia were recruited from January to April 2015. Nutritional status was assessed before treatment initiation, and patients were classified into three categories...
February 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28105771/the-interrater-and-test-retest-reliability-of-the-home-falls-and-accidents-screening-tool-home-fast-in-malaysia-using-raters-with-a-range-of-professional-backgrounds
#3
Muhammad Hibatullah Romli, Lynette Mackenzie, Meryl Lovarini, Maw Pin Tan, Lindy Clemson
RATIONALE, AIMS AND OBJECTIVES: Falls can be a devastating issue for older people living in the community, including those living in Malaysia. Health professionals and community members have a responsibility to ensure that older people have a safe home environment to reduce the risk of falls. Using a standardised screening tool is beneficial to intervene early with this group. The Home Falls and Accidents Screening Tool (HOME FAST) should be considered for this purpose; however, its use in Malaysia has not been studied...
January 20, 2017: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/28104710/protocol-of-a-feasibility-study-for-cognitive-assessment-of-an-ageing-cohort-within-the-southeast-asia-community-observatory-seaco-malaysia
#4
Devi Mohan, Blossom C M Stephan, Pascale Allotey, Carol Jagger, Mark Pearce, Mario Siervo, Daniel D Reidpath
INTRODUCTION: There is a growing proportion of population aged 65 years and older in low-income and middle-income countries. In Malaysia, this proportion is predicted to increase from 5.1% in 2010 to more than 15.4% by 2050. Cognitive ageing and dementia are global health priorities. However, risk factors and disease associations in a multiethnic, middle-income country like Malaysia may not be consistent with those reported in other world regions. Knowing the burden of cognitive impairment and its risk factors in Malaysia is necessary for the development of management strategies and would provide valuable information for other transitional economies...
January 19, 2017: BMJ Open
https://www.readbyqxmd.com/read/28104054/caregiver-burden-among-caregivers-of-individuals-with-severe-mental-illness-testing-the-moderation-and-mediation-models-of-resilience
#5
Zamzaliza Abdul Mulud, Geraldine McCarthy
The association between the socio-demographic characteristics of caregivers, such as gender and caregiver burden, is well documented; however, the process underlying this relationship is poorly understood. Based on the stress process model, we designed a cross-sectional study to examine the mediating and moderating effect of resilience on the relationship between gender and caregiver burden. Caregivers of individuals with severe mental illness (n=201) were recruited in two psychiatric outpatient clinics in Malaysia...
February 2017: Archives of Psychiatric Nursing
https://www.readbyqxmd.com/read/28097481/financial-development-and-sectoral-co2-emissions-in-malaysia
#6
Ibrahim Kabiru Maji, Muzafar Shah Habibullah, Mohd Yusof Saari
The paper examines the impacts of financial development on sectoral carbon emissions (CO2) for environmental quality in Malaysia. Since the financial sector is considered as one of the sectors that will contribute to Malaysian economy to become a developed country by 2020, we utilize a cointegration method to investigate how financial development affects sectoral CO2 emissions. The long-run results reveal that financial development increases CO2 emissions from the transportation and oil and gas sector and reduces CO2 emissions from manufacturing and construction sectors...
January 17, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28095446/neglected-intestinal-parasites-malnutrition-and-associated-key-factors-a-population-based-cross-sectional-study-among-indigenous-communities-in-sarawak-malaysia
#7
Yamuna Rajoo, Stephen Ambu, Yvonne Ai Lian Lim, Komalaveni Rajoo, Siew Chang Tey, Chan Woon Lu, Romano Ngui
Intestinal parasitic infections (IPIs) have been recognized as one of the most significant causes of illness among disadvantaged communities. Many studies have been conducted on the prevalence of IPIs in Malaysia. However, these studies mostly focused on the indigenous groups in Peninsular Malaysia. The present study was conducted to provide the current baseline data on prevalence of IPIs, anaemia, malnutrition and associated risk factors among the indigenous communities in Sarawak, situation at northwest Borneo island of Malaysia...
2017: PloS One
https://www.readbyqxmd.com/read/28094451/development-of-diversity-arrays-technology-markers-as-a-tool-for-rapid-genomic-assessment-in-nile-tilapia-oreochromis-niloticus
#8
C E Lind, A Kilian, J A H Benzie
The development of genomic markers is described for Nile tilapia, Oreochromis niloticus, using the Diversity Arrays Technology (DArT) genotype-by-sequencing platform. A total of 13 215 single nucleotide polymorphism (SNP) markers and 12 490 silicoDArT (dominant) markers were identified from broodstock of two selective breeding programs [Genetically Improved Farmed Tilapia (GIFT) strain from Malaysia and the Abbassa strain from Egypt]. Over 10 000 SNPs were polymorphic in either strain, and 2985 and 3087 showed strain-specific polymorphisms for the GIFT and Abbassa strains respectively...
January 17, 2017: Animal Genetics
https://www.readbyqxmd.com/read/28090185/characteristics-and-outcomes-of-patients-with-anterior-circulation-intracranial-aneurysm-managed-with-clipping-in-hospital-sungai-buloh
#9
Ailani Ab Ghani, Saiful Azli Mat Nayan, Regunath Kandasamy, Azmin Kas Rosman, Abdul Rahman Izani Ghani
INTRODUCTION: The annual incidence of intracranial aneurysm in Malaysia is estimated to be 1.1-1.7 per 100,000 population based on a study done conducted in 1988. Since then, little epidemiological research has been conducted in Malaysia, and the real incidence is therefore probably unreported despite advancements in the diagnosis and treatment of this disorder. Intracranial aneurysm may be treated by microsurgical clipping or embolisation depending on its location and the surgeon's preference...
November 2016: Malaysian Journal of Medical Sciences: MJMS
https://www.readbyqxmd.com/read/28090181/how-much-we-think-of-ourselves-and-how-little-we-think-of-others-an-investigation-of-the-neuronal-signature-of-self-consciousness-between-different-personality-traits-through-an-event-related-potential-study
#10
Auwal Bello Hassan, Tahamina Begum, Mohammed Faruque Reza, Nasir Yusoff
BACKGROUND: Previous studies have revealed that self-related tasks (items) receive more attention than non-self-related, and that they elicit event-related potential (ERP) components with larger amplitudes. Since personality has been reported as one of the biological correlates influencing these components, as well as our behavioural differences, it is important to examine how it affects our self-consciousness in relation to tasks of varied relevance and the neurological basis. METHODS: A total of 33 male and female undergraduate Malaysian medical students of Universiti Sains Malaysia (USM) participated in the study...
November 2016: Malaysian Journal of Medical Sciences: MJMS
https://www.readbyqxmd.com/read/28090179/correlation-of-demographic-and-clinical-characteristics-with-rheumatoid-factor-seropositivity-in-rheumatoid-arthritis-patients
#11
Maizatul Akmal Othman, Wan Syamimee Wan Ghazali, Nurul Khaiza Yahya, Kah Keng Wong
BACKGROUND: The rheumatoid factor (RF) blood test is the most commonly adopted test for the diagnosis of rheumatoid arthritis (RA). RA patients who are seropositive for RF might face a greater likelihood of developing more aggressive symptoms. METHODS: Our goal was to study the demographic and clinical characteristics, as well as their correlation with RF seropositivity, among a series of 80 RA patients aged ≥ 18 years who attend Hospital Universiti Sains Malaysia (HUSM)...
November 2016: Malaysian Journal of Medical Sciences: MJMS
https://www.readbyqxmd.com/read/28090178/median-survival-time-of-endometrial-cancer-patients-with-lymphovascular-invasion-at-the-hospital-universiti-sains-malaysia
#12
Wan Adnan Wan Nor Asyikeen, Ab Hamid Siti-Azrin, Nur Asyilla Che Jalil, Anani Aila Mat Zin, Nor Hayati Othman
BACKGROUND: Endometrial cancer is the most common gynaecologic malignancy among females worldwide. The purpose of this study was to determine the median survival time of endometrial cancer patients at the Hospital Universiti Sains Malaysia (USM). METHODS: A list of 121 endometrial cancer cases registered at Hospital USM between 2000 until 2011 was retrospectively reviewed. The survival time of the endometrial cancer patients was estimated by Kaplan-Meier survival analysis...
November 2016: Malaysian Journal of Medical Sciences: MJMS
https://www.readbyqxmd.com/read/28088124/nipah-virus-transmission-of-a-zoonotic-paramyxovirus
#13
REVIEW
Bronwyn Anne Clayton
Nipah virus is a recently-recognised, zoonotic paramyxovirus that causes severe disease and high fatality rates in people. Outbreaks have occurred in Malaysia, Singapore, India and Bangladesh, and a putative Nipah virus was also recently associated with human disease in the Philippines. Worryingly, human-to-human transmission is common in Bangladesh, where outbreaks occur with near-annual frequency. Onward human transmission of Nipah virus in Bangladesh is associated with close contact with clinically-unwell patients or their infectious secretions...
January 11, 2017: Current Opinion in Virology
https://www.readbyqxmd.com/read/28087963/vitamin-d-deficiency-rickets-even-with-abundant-sunlight-a-case-to-highlight-emerging-problem
#14
T H Ting, A S Devnani
We describe a case of vitamin-D-deficiency rickets in a young child to highlight its existence in Malaysia where sunlight is abundant throughout the year. The child presented with deformity of both legs. He came from an educated urban family but remained indoors most of the time. Radiographs of knees and wrists showed changes of florid rickets. Low serum 25-hydoxyvitamin-D, high parathyroid hormone, normal serum phosphate and calcium levels, and normal renal function clinched the diagnosis of vitamin-D-deficiency rickets...
December 2016: Medical Journal of Malaysia
https://www.readbyqxmd.com/read/28087957/cardiovascular-risk-assessment-between-urban-and-rural-population-in-malaysia
#15
I Noor Hassim, M R Norazman, M Diana, Y Khairul Hazdi, I Rosnah
INTRODUCTION: Cardiovascular disease (CVD) caused significant burden to Malaysia as it accounted for 36% of total deaths. This study aims to evaluate the burden of cardiovascular risk factors among Malaysian adult and assess the difference between urban and rural population in the selected communities. METHODS: This study is part of the ongoing Prospective Urban Rural Epidemiology (PURE) database, whereby the baseline data were collected since June 2008. CVD risk was measured using INTERHEART risk score which comprised of eleven risk factors i...
December 2016: Medical Journal of Malaysia
https://www.readbyqxmd.com/read/28087953/tenofovir-induced-nephrotoxicity-a-retrospective-cohort-study
#16
H M Koh, K Suresh
BACKGROUND: Tenofovir (TDF) has been associated with renal function deterioration, but local data regarding the incidence and risk factors for this adverse event were lacking. OBJECTIVES: To determine the incidence of nephrotoxicity in HIV-infected patients on tenofovir-based regimens and to evaluate risk factors involved in tenofovir-associated renal function decline. METHODS: This is a single-centre retrospective cohort study of 440 HIV-infected adults who were started on tenofovirbased antiretroviral regimens...
December 2016: Medical Journal of Malaysia
https://www.readbyqxmd.com/read/28087920/spatial-and-temporal-variation-of-water-quality-in-the-bertam-catchment-cameron-highlands-malaysia
#17
G Rasul
The spatio-temporal variability of water quality associated with anthropogenic activities was studied for the Bertam River and its main tributaries within the Bertam Catchment, Cameron Highlands, Malaysia. A number of physico-chemical parameters of collected samples were analyzed to evaluate their spatio-temporal variability. Non-parametric statistical analysis showed significant temporal and spatial differences (p<0.05) in most of the parameters across the Catchment. Parameters except DO and COD displayed higher values in rainy season...
December 16, 2016: Water Environment Research: a Research Publication of the Water Environment Federation
https://www.readbyqxmd.com/read/28087772/possible-roles-of-new-mutations-shared-by-asian-and-american-zika-viruses
#18
Shozo Yokoyama, William T Starmer
Originating in Africa, the Zika virus (ZIKV) has spread to Asia, Pacific Islands and now to the Americas and beyond. Since the first isolation in 1947, ZIKV strains have been sampled at various times in the last 69 years, but this history has not been reflected in studying the patterns of mutation accumulation in their genomes. Implementing the viral history, we show that the ZIKV ancestor appeared sometime in 1930-1945 and, at that point, its mutation rate was probably less than 0.2 x 10(-3)/nucleotide site/year and subsequently increased significantly in most of its descendants...
January 12, 2017: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/28087349/combination-of-multiple-ligation-dependent-probe-amplification-and-illumina-miseq-amplicon-sequencing-for-tsc1-tsc2-gene-analyses-in-patients-with-tuberous-sclerosis-complex
#19
Nur Farrah Dila Ismail, Abdul Qawee Rani, Nik Mohd Ariff Nik Abdul Malik, Chia Boon Hock, Siti Nabilahuda Mohd Azlan, Salmi Abdul Razak, Wee Teik Keng, Lock Hock Ngu, Abdul Rashid Silawati, Nor AzniYahya, Narazah Mohd Yusoff, Teguh Haryo Sasongko, Zabidi Azhar Mohd Hussin
Tuberous sclerosis complex (TSC) is an autosomal dominant neurocutaneous disorder characterized by tumor growth in multiple organs and caused by mutations in either TSC1 or TSC2 genes. Because of their relatively large genomic sizes, absence of hotspots, and common type of mutations, mutation detection in TSC1 and TSC2 genes has been challenging. We devised a combination of multiple ligation-dependent probe amplification (MLPA) and amplicon sequencing (AS) to simplify the detection strategy, yet we come up with reasonably high detection rate...
January 10, 2017: Journal of Molecular Diagnostics: JMD
https://www.readbyqxmd.com/read/28086789/detection-of-plasmodium-knowlesi-plasmodium-falciparum-and-plasmodium-vivax-using-loop-mediated-isothermal-amplification-lamp-in-a-co-endemic-area-in-malaysia
#20
Kim A Piera, Ammar Aziz, Timothy William, David Bell, Iveth J González, Bridget E Barber, Nicholas M Anstey, Matthew J Grigg
BACKGROUND: Plasmodium knowlesi is the most common cause of malaria in Malaysia. However, microscopic diagnosis is inaccurate and rapid diagnostic tests (RDTs) are insufficiently sensitive. PCR is sensitive and specific but not feasible at a district level. Loop-mediated isothermal amplification (LAMP) shows potential with only basic requirements. A commercially available LAMP assay, the Eiken Loopamp™ MALARIA Pan Detection kit, is sensitive for Plasmodium falciparum and Plasmodium vivax, but has not previously been evaluated for P...
January 13, 2017: Malaria Journal
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