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https://www.readbyqxmd.com/read/29449547/inference-of-field-reversed-configuration-topology-and-dynamics-during-alfvenic-transients
#1
J A Romero, S A Dettrick, E Granstedt, T Roche, Y Mok
Active control of field reversed configuration (FRC) devices requires a method to determine the flux surface geometry and dynamic properties of the plasma during both transient and steady-state conditions. The current tomography (CT) method uses Bayesian inference to determine the plasma current density distribution using both the information from magnetic measurements and a physics model in the prior. Here we show that, from the inferred current sources, the FRC topology and its axial stability properties are readily obtained...
February 15, 2018: Nature Communications
https://www.readbyqxmd.com/read/29448711/investigation-of-gate-stacked-in-ga-zn-o-tfts-with-ga-zn-o-source-drain-electrodes-by-atmospheric-pressure-plasma-enhanced-chemical-vapor-deposition
#2
Chien-Hung Wu, Kow-Ming Chang, Yi-Ming Chen, Bo-Wen Huang, Yu-Xin Zhang, Shui-Jinn Wang, Jui-Mei Hsu
Atmospheric pressure plasma-enhanced chemical vapor deposition (AP-PECVD) was employed for the fabrication of indium gallium zinc oxide thin-film transistors (IGZO TFTs) with high transparent gallium zinc oxide (GZO) source/drain electrodes. The influence of post-deposition annealing (PDA) temperature on GZO source/drain and device performance was studied. Device with a 300 °C annealing demonstrated excellent electrical characteristics with on/off current ratio of 2.13 × 108, saturation mobility of 10 cm2/V-s, and low subthreshold swing of 0...
March 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29447367/endometrial-natural-killer-nk-cells-reveal-a-tissue-specific-receptor-repertoire
#3
D Feyaerts, T Kuret, B van Cranenbroek, S van der Zeeuw-Hingrez, O W H van der Heijden, A van der Meer, I Joosten, R G van der Molen
STUDY QUESTION: Is the natural killer (NK) cell receptor repertoire of endometrial NK (eNK) cells tissue-specific? SUMMARY ANSWER: The NK cell receptor (NKR) expression profile in pre-pregnancy endometrium appears to have a unique tissue-specific phenotype, different from that found in NK cells in peripheral blood, suggesting that these cells are finely tuned towards the reception of an allogeneic fetus. WHAT IS KNOWN ALREADY: NK cells are important for successful pregnancy...
February 13, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29446442/characterization-of-source-plasma-from-self-identified-vaccinated-or-convalescent-donors-during-the-2009-h1n1-pandemic
#4
Alexey Khalenkov, Yong He, Jennifer L Reed, Thomas R Kreil, John McVey, Malgorzata Norton, John Scott, Dorothy E Scott
BACKGROUND: Influenza immune globulin, manufactured from plasma of convalescent or vaccinated donors has been proposed as a potential therapy for severe influenza. In 2009, a program was initiated to collect plasma from donors who self-identified as having had H1N1 influenza or having received the H1N1 pandemic vaccine. The goal of this study was to determine the efficiency of donor screening by self-identification without antibody testing, and to evaluate demographic predictors of high-titer donations...
February 15, 2018: Transfusion
https://www.readbyqxmd.com/read/29445912/plasma-elemental-responses-to-red-meat-ingestion-in-healthy-young-males-and-the-effect-of-cooking-method
#5
Matthew P G Barnett, Vic S C Chiang, Amber M Milan, Shikha Pundir, Trevor A Walmsley, Susan Grant, James F Markworth, Siew-Young Quek, Peter M George, David Cameron-Smith
PURPOSE: Elemental deficiencies are highly prevalent and have a significant impact on health. However, clinical monitoring of plasma elemental responses to foods remains largely unexplored. Data from in vitro studies show that red meat (beef) is a highly bioavailable source of several key elements, but cooking method may influence this bioavailability. We therefore studied the postprandial responses to beef steak, and the effects of two different cooking methods, in healthy young males...
February 14, 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/29445369/turgor-pressure-and-possible-constriction-mechanisms-in-bacterial-division
#6
REVIEW
Masaki Osawa, Harold P Erickson
Bacterial cytokinesis begins with the assembly of FtsZ into a Z ring at the center of the cell. The Z-ring constriction in Gram-negative bacteria may occur in an environment where the periplasm and the cytoplasm are isoosmotic, but in Gram-positive bacteria the constriction may have to overcome a substantial turgor pressure. We address three potential sources of invagination force. (1) FtsZ itself may generate force by curved protofilaments bending the attached membrane. This is sufficient to constrict liposomes in vitro ...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29444011/complementary-metal-oxide-semiconductor-compatible-source-of-single-photons-at-near-visible-wavelengths
#7
Robert Cernansky, Francesco Martini, Alberto Politi
We demonstrate on-chip generation of correlated pairs of photons in the near-visible spectrum using a CMOS compatible plasma-enhanced chemical vapor deposition silicon nitride photonic device. Photons are generated via spontaneous four wave mixing enhanced by a ring resonator with high intrinsic quality Q-factor of 3,20,000, resulting in a generation rate of 950,000  pairsmW. The high brightness of this source offers the opportunity to expand photonic quantum technologies over a broad wavelength range and provides a path to develop fully integrated quantum chips working at room temperature...
February 15, 2018: Optics Letters
https://www.readbyqxmd.com/read/29441425/detailed-analysis-of-the-plasma-extracellular-vesicle-proteome-after-separation-from-lipoproteins
#8
Nasibeh Karimi, Aleksander Cvjetkovic, Su Chul Jang, Rossella Crescitelli, Mohammad Ali Hosseinpour Feizi, Rienk Nieuwland, Jan Lötvall, Cecilia Lässer
The isolation of extracellular vesicles (EVs) from blood is of great importance to understand the biological role of circulating EVs and to develop EVs as biomarkers of disease. Due to the concurrent presence of lipoprotein particles, however, blood is one of the most difficult body fluids to isolate EVs from. The aim of this study was to develop a robust method to isolate and characterise EVs from blood with minimal contamination by plasma proteins and lipoprotein particles. Plasma and serum were collected from healthy subjects, and EVs were isolated by size-exclusion chromatography (SEC), with most particles being present in fractions 8-12, while the bulk of the plasma proteins was present in fractions 11-28...
February 13, 2018: Cellular and Molecular Life Sciences: CMLS
https://www.readbyqxmd.com/read/29440772/electro-optic-spatial-decoding-on-the-spherical-wavefront-coulomb-fields-of-plasma-electron-sources
#9
K Huang, T Esirkepov, J K Koga, H Kotaki, M Mori, Y Hayashi, N Nakanii, S V Bulanov, M Kando
Detections of the pulse durations and arrival timings of relativistic electron beams are important issues in accelerator physics. Electro-optic diagnostics on the Coulomb fields of electron beams have the advantages of single shot and non-destructive characteristics. We present a study of introducing the electro-optic spatial decoding technique to laser wakefield acceleration. By placing an electro-optic crystal very close to a gas target, we discovered that the Coulomb field of the electron beam possessed a spherical wavefront and was inconsistent with the previously widely used model...
February 13, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29439437/sub-thz-imaging-using-non-resonant-hemt-detectors
#10
Juan A Delgado-Notario, Jesus E Velazquez-Perez, Yahya M Meziani, Kristel Fobelets
Plasma waves in gated 2-D systems can be used to efficiently detect THz electromagnetic radiation. Solid-state plasma wave-based sensors can be used as detectors in THz imaging systems. An experimental study of the sub-THz response of II-gate strained-Si Schottky-gated MODFETs (Modulation-doped Field-Effect Transistor) was performed. The response of the strained-Si MODFET has been characterized at two frequencies: 150 and 300 GHz: The DC drain-to-source voltage transducing the THz radiation (photovoltaic mode) of 250-nm gate length transistors exhibited a non-resonant response that agrees with theoretical models and physics-based simulations of the electrical response of the transistor...
February 10, 2018: Sensors
https://www.readbyqxmd.com/read/29438900/sperm-quality-biomarkers-complement-reproductive-and-endocrine-parameters-in-investigating-environmental-contaminants-in-common-carp-cyprinus-carpio-from-the-lake-mead-national-recreation-area
#11
Jill A Jenkins, Michael R Rosen, Rassa O Draugelis-Dale, Kathy R Echols, Leticia Torres, Carla M Wieser, Constance A Kersten, Steven L Goodbred
Lake Mead National Recreational Area (LMNRA) serves as critical habitat for several federally listed species and supplies water for municipal, domestic, and agricultural use in the Southwestern U.S. Contaminant sources and concentrations vary among the sub-basins within LMNRA. To investigate whether exposure to environmental contaminants is associated with alterations in male common carp (Cyprinus carpio) gamete quality and endocrine- and reproductive parameters, data were collected among sub-basins over 7 years (1999-2006)...
February 10, 2018: Environmental Research
https://www.readbyqxmd.com/read/29437728/large-vessel-stroke-as-initial-presentation-of-thrombotic-thrombocytopenic-purpura
#12
Ryan Sugarman, Andrea M Tufano, Johnson M Liu
A 67-year-old right-handed woman presented with dysarthria, left upper extremity weakness and right-sided neglect of 3 hours duration. Imaging of the brain revealed acute right middle cerebral artery stroke; however, tissue plasminogen activator could not be administered due to severe thrombocytopenia. A peripheral smear revealed schistocytes and the patient was treated empirically for thrombotic thrombocytopenic purpura (TTP) with therapeutic plasma exchange. An extensive workup revealed no embolic source or other cause for stroke, and a diagnosis of large vessel infarct secondary to TTP was made...
February 5, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29436170/simultaneous-determination-and-pharmacokinetics-study-of-four-quinones-in-rat-plasma-by-uhplc-esi-ms-ms-after-the-oral-administration-of-qianzhi-capsules
#13
Mingjie Gao, Zhibin Wang, Jing Yang, Liqian Wang, Chengcui Wu, Binbin Cui, Chunjuan Yang
A sensitive, specific, and accurate ultra high performance liquid chromatography with electrospray ionization tandem mass spectrometry method was developed and validated for the simultaneous quantification of purpurin, munjistin, mollugin and alizarin from Qianzhi capsules in rat plasma. Chromatographic separation was performed on an Aglient Eclipse Plus C18 RRHD column with a mobile phase consisting of methanol and 5 mM ammonium acetate/water with gradient elution. The analytes were quantified on a triple quadrupole mass spectrometer, operating in the multiple reaction monitoring mode and switching the electrospray ion source polarity with positive electrospray ionization in a single run...
February 13, 2018: Journal of Separation Science
https://www.readbyqxmd.com/read/29436084/clinical-trials-and-registries-in-haemophilia-opponents-or-collaborators-comparison-of-pup-data-derived-from-different-data-sources
#14
C Keipert, C J Jonker, H M van den Berg, A Hilger
INTRODUCTION: The "Guideline on the clinical investigation of recombinant and human plasma-derived factor VIII products" (ClinGL) provides the requirements for the performing of clinical trials (CTs) for marketing authorization in Europe. The number of eligible previously untreated patients (PUPs) for CTs might be difficult to meet because of the concurrent development of FVIII concentrates, and additional data sources must be explored. AIM: The extent to which CTs and the PedNet registry met relevant parameters, identified in the ClinGL, as well as inhibitor incidences were investigated in patients from both sources...
February 13, 2018: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/29435679/geospatial-distribution-of-metal-loid-s-and-human-health-risk-assessment-due-to-intake-of-contaminated-groundwater-around-an-industrial-hub-of-northern-india
#15
Rachit Kashyap, K S Verma, Sanjay Kr Uniyal, S K Bhardwaj
The study focused on analyzing concentrations of metal(loid)s, their geospatial distribution in groundwater around an industrial hub of northern India. Human health risk posed due to the intake of contaminated groundwater was also evaluated. For this, 240 samples were assayed using inductively coupled plasma emission spectrophotometer. For risk assessment, the methodology proposed by US Environmental Protection Agency was adopted. Geometric mean of Al, As, Mo, Cd, Co, Cr, Fe, Mn, Ni, Pb, Se, and Zn was 193...
February 12, 2018: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29432918/exploration-of-the-platelet-proteome-in-patients-with-early-stage-cancer
#16
Siamack Sabrkhany, Marijke J E Kuijpers, Jaco C Knol, Steven W M Olde Damink, Anne-Marie C Dingemans, Henk M Verheul, Sander R Piersma, Thang V Pham, Arjan W Griffioen, Mirjam G A Oude Egbrink, Connie R Jimenez
Platelets play an important role in tumor growth and, at the same time, platelet characteristics are affected by cancer presence. Therefore, we investigated whether the platelet proteome harbors differentially expressed proteins associated with early-stage cancer. For this proof-of-concept study, patients with early-stage lung (n = 8) or head of pancreas cancer (n = 4) were included, as were healthy sex- and age-matched controls for both subgroups. Blood samples were collected from controls and from patients before surgery...
February 9, 2018: Journal of Proteomics
https://www.readbyqxmd.com/read/29432586/effects-of-different-starch-source-of-starter-on-small-intestinal-growth-and-endogenous-glp-2-secretion-in-pre-weaned-lambs
#17
Daming Sun, Hongwei Li, Shengyong Mao, Weiyun Zhu, Junhua Liu
The objective of this study was to investigate the effects of different source of starch in starter feed on small intestinal growth and endogenous glucagon-like peptide 2 (GLP-2) secretion in pre-weaned lambs. Twenty-four 10-day-old lambs were divided into three groups that were treated with different iso-starch diets containing purified cassava starch (CS, n = 8), maize starch (MS, n = 8) and pea starch (PS, n = 8). At 56 days old, there was no significant difference in final body weight (BW) of lambs among the three groups...
February 8, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29432445/promising-effects-of-xanthine-oxidase-inhibition-by-allopurinol-on-autonomic-heart-regulation-estimated-by-heart-rate-variability-hrv-analysis-in-rats-exposed-to-hypoxia-and-hyperoxia
#18
Stanisław Zajączkowski, Wiesław Ziółkowski, Piotr Badtke, Miłosz A Zajączkowski, Damian J Flis, Adam Figarski, Maria Smolińska-Bylańska, Tomasz H Wierzba
BACKGROUND: It has long been suggested that reactive oxygen species (ROS) play a role in oxygen sensing via peripheral chemoreceptors, which would imply their involvement in chemoreflex activation and autonomic regulation of heart rate. We hypothesize that antioxidant affect neurogenic cardiovascular regulation through activation of chemoreflex which results in increased control of sympathetic mechanism regulating heart rhythm. Activity of xanthine oxidase (XO), which is among the major endogenous sources of ROS in the rat has been shown to increase during hypoxia promote oxidative stress...
2018: PloS One
https://www.readbyqxmd.com/read/29428743/circulating-progesterone-concentrations-in-nonlactating-holstein-cows-during-reuse-of-intravaginal-progesterone-implants-sanitized-by-autoclave-or-chemical-disinfection
#19
L F Melo, P L J Monteiro, L H Oliveira, M M Guardieiro, J N Drum, M C Wiltbank, R Sartori
The aim of this study was to compare plasma progesterone (P4) concentrations in nonlactating, multiparous Holstein cows (n = 24) treated with 2 types of intravaginal implants containing either 1.0 or 1.9 g of P4 either at the first use or during reuse of the implants after sanitizing the implant by autoclave or chemical disinfection. In a completely randomized design with a 2 × 3 factorial arrangement and 2 replicates, every cow underwent 2 of 6 treatments. Two sources of P4 [controlled internal drug release (1...
February 7, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29425024/human-suction-blister-fluid-composition-determined-using-high-resolution-metabolomics
#20
Megan Niedzwiecki, Pradnya Samant, Douglas I Walker, ViLinh Tran, Dean P Jones, Mark R Prausnitz, Gary W Miller
Interstitial fluid (ISF) surrounds the cells and tissues of the body. Since ISF has molecular components similar to plasma, as well as compounds produced locally in tissues, it may be a valuable source of biomarkers for diagnostics and monitoring. However, there has not been a comprehensive study to determine the metabolite composition of ISF and compare it to plasma. In this study, the metabolome of suction blister fluid (SBF), which is largely comprised of ISF, collected from 10 human volunteers was analyzed using untargeted high-resolution metabolomics (HRM)...
February 9, 2018: Analytical Chemistry
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