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dyslipidemia in elderly

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https://www.readbyqxmd.com/read/29875899/prevalence-of-hypertension-and-hypertension-control-rates-among-elderly-adults-during-the-cold-season-in-rural-northeast-china-a-cross-sectional-study
#1
Nobuo Kawazoe, Xiumin Zhang, Chifa Chiang, Hongjian Liu, Jinghua Li, Yoshihisa Hirakawa, Atsuko Aoyama
Objective: The burden of noncommunicable diseases (NCDs) is increasing in China, together with economic development and social changes. The prevalence of risk factors for NCDs, such as overweight/obesity, hypertension, diabetes, and dyslipidemia, is reported to be high even among poor residents of rural areas. We aimed to investigate the prevalence of hypertension among elderly adults in rural Northeast China and the proportion with controlled hypertension among those on antihypertensive medication (hypertension control rate)...
May 2018: Journal of Rural Medicine: JRM
https://www.readbyqxmd.com/read/29864738/physical-frailty-and-cognitive-function-among-men-with-cardiovascular-disease
#2
Galit Weinstein, Miri Lutski, Uri Goldbourt, David Tanne
AIMS: To assess the relationship between physical frailty and cognitive function among elderly men with a history of cardiovascular disease (CVD). METHODS: Three-hundred-twenty-four community-dwelling men with chronic CVD (mean age 77.2 ± 6.4 years) who previously participated in the Bezafibrate Infarction Prevention (BIP) trial (1990-1998) underwent assessment of frailty and cognitive function between 2011 and 2013. Physical frailty was assessed using the Fried phenotypic model, and cognitive performance overall and in memory, executive function, visuospatial and attention domains was evaluated using a validated set of computerized cognitive tests...
May 29, 2018: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29803601/cognitive-impairment-vulnerability-and-mortality-post-ischemic-stroke-a-five-year-follow-up-of-the-action-on-secondary-prevention-interventions-and-rehabilitation-in-stroke-aspire-s-cohort
#3
Eva Gaynor, Daniela Rohde, Margaret Large, Lisa Mellon, Patricia Hall, Linda Brewer, Orla Conway, Anne Hickey, Kathleen Bennett, Eamon Dolan, Elizabeth Callaly, David Williams
BACKGROUND: The aim of this study was to examine predictors of mortality in patients 5 years after ischemic stroke, focusing on cognitive impairment, vulnerability, and vascular risk factors assessed at 6 months post stroke. MATERIALS AND METHODS: Patients from the Action on Secondary Prevention Interventions and Rehabilitation in Stroke (ASPIRE-S) cohort were followed up 5 years post ischemic stroke. Vascular risk factors, cognitive impairment, and vulnerability were assessed at 6 months post stroke...
May 23, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29799416/an-update-on-physical-health-and-economic-consequences-of-overweight-and-obesity
#4
REVIEW
Dinh-Toi Chu, Nguyen Thi Minh Nguyet, Thien Chu Dinh, Nguyen Vu Thai Lien, Khanh-Hoang Nguyen, Vo Truong Nhu Ngoc, Yang Tao, Le Hoang Son, Duc-Hau Le, Vu Bich Nga, Adam Jurgoński, Quoc-Hung Tran, Pham Van Tu, Van-Huy Pham
Overweight and obesity (OW and OB) have been on the increase globally and posed health risks to the world's population of all ages, including pre-born babies, children, adolescents, adults and elderly people, via their comorbid conditions. Excellent examples of comorbidities associated with obesity include cancer, cardiovascular diseases (CVD) and type 2 diabetes mellitus (T2DM). In this article, we aimed to review and update scientific evidence regarding the relationships between obesity and its common physical health consequences, including CVD, T2DM, hypertension, ischemic stroke, cancer, dyslipidemia and reproductive disorders...
May 5, 2018: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/29794411/association-of-n-terminal-pro-b-type-natriuretic-peptide-with-blood-pressure-and-pulse-pressure-in-elderly-people-a-cross-sectional-population-study
#5
Nobuo Sasaki, Hideya Yamamoto, Ryoji Ozono, Saeko Fujiwara, Yasuki Kihara
BACKGROUND: N-Terminal pro B-type natriuretic peptide (NT-proBNP) is widely used as a marker of ventricular dysfunction. However, data regarding the association of NT-proBNP with blood pressure (BP) and pulse pressure (PP) in the elderly population are limited.Methods and Results:The present cross-sectional study involved 6,529 participants, aged ≥70 years, without cardiovascular disease (CVD), who underwent general health examinations. Serum NT-proBNP concentrations were determined, with high NT-proBNP concentrations defined as those ≥125 pg/mL...
May 23, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29793176/non-ldl-dyslipidemia-is-prevalent-in-the-young-and-determined-by-lifestyle-factors-and-age-the-lifelines-cohort
#6
Jeroen K de Vries, Jan W Balder, Michelle J Pena, Petra Denig, Andries J Smit
BACKGROUND AND AIMS: Non-LDL dyslipidemia (NLD) confers cardiovascular risk, and prevalence rates appear to be high in elderly populations. Small cohorts have identified several lifestyle, anthropometric, and medical factors associated with NLD. We aimed to assess sex- and age-specific prevalence of NLD in a contemporary population cohort (n = 167 729), and to identify independent determinants of NLD, focusing on lifestyle, anthropometric, and medical factors. METHODS: The prevalence of NLD was assessed per 10-year age intervals in adults without cardiovascular disease not using lipid-modifying drugs from the Dutch LifeLines cohort...
May 21, 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29768343/potential-common-factors-associated-with-predisposition-to-common-cold-in-middle-aged-and-elderly-japanese-a-community-based-cross-sectional-study
#7
Michi Shibata, Taizo Iwane, Ryoko Higuchi, Kaname Suwa, Kei Nakajima
People worldwide frequently catch a common cold, which occasionally develops into secondary severe conditions such as pneumonia. However, it is unclear whether predisposition to the common cold is associated with the individual's characteristics including age, body weight, lifestyles, diets, and intestinal functions, besides exposure to a responsible pathogen. We addressed this issue epidemiologically considering many relevant clinical factors.We reviewed data from a cross-sectional study consisting of 39,524 apparently healthy Japanese aged 40 to 79 years (26,975 men and 12,549 women) who underwent a checkup in 2007...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29728915/results-meta-analysis-and-a-first-evaluation-of-u-nox-r-the-urinary-nitrate-to-nitrite-molar-ratio-as-a-measure-of-nitrite-reabsorption-in-experimental-and-clinical-settings
#8
Dimitrios Tsikas, Erik Hanff, Alexander Bollenbach, Ruan Kruger, Vu Vi Pham, Kristine Chobanyan-Jürgens, Dirk Wedekind, Tanja Arndt, Anne Jörns, Jimmy F P Berbée, Hans M G Princen, Thomas Lücke, François Mariotti, Jean-François Huneau, Stefan Ückert, Jürgen C Frölich, Sigurd Lenzen
We recently found that renal carbonic anhydrase (CA) is involved in the reabsorption of inorganic nitrite (NO2 - ), an abundant reservoir of nitric oxide (NO) in tissues and cells. Impaired NO synthesis in the endothelium and decreased NO bioavailability in the circulation are considered major contributors to the development and progression of renal and cardiovascular diseases in different conditions including diabetes. Isolated human and bovine erythrocytic CAII and CAIV can convert nitrite to nitrous acid (HONO) and its anhydride N2 O3 which, in the presence of thiols (RSH), are further converted to S-nitrosothiols (RSNO) and NO...
May 4, 2018: Amino Acids
https://www.readbyqxmd.com/read/29703506/safety-and-short-term-outcomes-of-laparoscopic-sleeve-gastrectomy-for-patients-over-65-years-old-with-severe-obesity
#9
Panagiotis Lainas, Carmelisa Dammaro, Martin Gaillard, Gianfranco Donatelli, Hadrien Tranchart, Ibrahim Dagher
BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) is a widely accepted, stand-alone bariatric operation. Data on elderly patients undergoing LSG are scarce. OBJECTIVES: The aim of this study was to demonstrate that LSG is safe and effective for patients>65 years old with severe obesity. SETTING: Department of Minimally Invasive Digestive Surgery, Antoine-Beclere Hospital, AP-HP, Paris-Saclay University, France. METHODS: Prospectively collected data from consecutive patients undergoing LSG were retrospectively analyzed...
March 8, 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29694704/self-reported-snoring-is-associated-with-chronic-kidney-disease-independent-of-metabolic-syndrome-in-middle-aged-and-elderly-chinese
#10
Jun Song, Chuan Wang, Aixia Ma, Huizhen Zheng, Wenjian Zheng, Xinguo Hou, Cheng Hu, Li Chen, Weiping Jia
AIMS: To investigate the correlation between snoring and chronic kidney disease (CKD) and explore whether metabolic syndrome (MetS) plays an important role in this relationship among middle-aged and elderly Chinese. METHODS: The subjects included in this study were categorized into 3 subgroups based on self-reported snoring frequency (regularly [≥ 3 times per week], occasionally [between "regularly" and "never"] or never [< 1 time per month])...
April 25, 2018: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/29678607/association-between-hypertension-and-metabolic-disorders-among-elderly-patients-in-north-jordan
#11
Nuha Alwardat, Laura Di Renzo, Renata Costa de Miranda, Sofian Alwardat, Paola Sinibaldi Salimei, Antonino De Lorenzo
BACKGROUND: Hypertension (HTN), dyslipidemia and hyperglycemia are major risk factors for cardiovascular disease, accounting for the highest morbidity and mortality among the elderly Jordanian population. This study aimed to evaluate serum lipid and glucose profiles of hypertensive patients and normotensive controls, and determine the risk factors for HTN among elderly population in Jordan. METHODS: A cross-sectional study was carried out among 200 participants, including 111 hypertensive patients and 89 normotensive controls from June to October 2017 in North Jordan...
April 12, 2018: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/29605539/integrated-flow-mediated-vasodilation-response-predicts-cardiovascular-events-in-elderly-patients-with-cardiovascular-risk-factors-the-japan-morning-surge-home-blood-pressure-study
#12
Tomoyuki Kabutoya, Satoshi Hoshide, Kazuomi Kario
The integrated flow-mediated vasodilation (FMD) response has been associated with cardiovascular (CV) risk factors, but the association between the integrated FMD response and subsequent CV events has been unclear. We enrolled 555 patients who had at least one CV risk factor (hypertension, dyslipidemia, diabetes, or smoking). We measured the peak percentage change in diameter (ΔFMD), and integrated FMD response calculated as the area under the dilation curve over a 120-second dilation period (FMD-AUC120 )...
May 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29601472/association-between-short-term-exposure-to-air-pollution-and-dyslipidemias-among-type-2-diabetic-patients-in-northwest-china-a-population-based-study
#13
Minzhen Wang, Shan Zheng, Yonghong Nie, Jun Weng, Ning Cheng, Xiaobin Hu, Xiaowei Ren, Hongbo Pei, Yana Bai
Air pollution exposure may play an adverse role in diabetes. However, little data are available directly evaluating the effects of air pollution exposure in blood lipids of which dysfunction has been linked to diabetes or its complications. We aimed to evaluate the association between air pollution and lipids level among type 2 diabetic patients in Northwest China. We performed a population-based study of 3912 type 2 diabetes patients in an ongoing cohort study in China. Both spline and multiple linear regressions analysis were used to examine the association between short-term exposure to PM10 , SO₂, NO₂ and total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C)...
March 30, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29519962/-prevention-of-dementia-with-special-reference-to-lifestyle-and-vascular-risk-factors
#14
Haruo Hanyu
There is a wide range of potentially modifiable risk factors for Alzheimer's disease and dementia, including cardiovascular risk factors (e.g. hypertension, diabetes, dyslipidemia, obesity, sleep-apnea syndrome), psychosocial factors (e.g., depression), health behaviors (e.g., low level of physical or mental activity, smoking status), and head trauma. In the elderly, weight loss associated with frailty and sarcopenia is another risk factor for dementia. Recent epidemiological studies have shown that the prevalence of dementia has declined in the US and European countries during the last 20 years...
March 2018: Brain and Nerve, Shinkei Kenkyū No Shinpo
https://www.readbyqxmd.com/read/29519347/10-year-resource-utilization-and-costs-for-cardiovascular-care
#15
Leslee J Shaw, Abhinav Goyal, Christina Mehta, Joe Xie, Lawrence Phillips, Anita Kelkar, Joseph Knapper, Daniel S Berman, Khurram Nasir, Emir Veledar, Michael J Blaha, Roger Blumenthal, James K Min, Reza Fazel, Peter W F Wilson, Matthew J Budoff
BACKGROUND: Cardiovascular disease (CVD) imparts a heavy economic burden on the U.S. health care system. Evidence regarding the long-term costs after comprehensive CVD screening is limited. OBJECTIVES: This study calculated 10-year health care costs for 6,814 asymptomatic participants enrolled in MESA (Multi-Ethnic Study of Atherosclerosis), a registry sponsored by the National Heart, Lung, and Blood Institute, National Institutes of Health. METHODS: Cumulative 10-year costs for CVD medications, office visits, diagnostic procedures, coronary revascularization, and hospitalizations were calculated from detailed follow-up data...
March 13, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29480185/designing-an-internet-based-multidomain-intervention-for-the-prevention-of-cardiovascular-disease-and-cognitive-impairment-in-older-adults-the-hatice-trial
#16
Mariagnese Barbera, Francesca Mangialasche, Susan Jongstra, Juliette Guillemont, Tiia Ngandu, Cathrien Beishuizen, Nicola Coley, Carol Brayne, Sandrine Andrieu, Edo Richard, Hilkka Soininen, Miia Kivipelto
BACKGROUND: Many dementia and cardiovascular disease (CVD) cases in older adults are attributable to modifiable vascular and lifestyle-related risk factors, providing opportunities for prevention. In the Healthy Aging Through Internet Counselling in the Elderly (HATICE) randomized controlled trial, an internet-based multidomain intervention is being tested to improve the cardiovascular risk (CVR) profile of older adults. OBJECTIVE: To design a multidomain intervention to improve CVR, based on the guidelines for CVR management, and administered through a coach-supported, interactive, platform to over 2500 community-dwellers aged 65+ in three European countries...
2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29477559/hearing-loss-is-associated-with-increased-chd-risk-and-unfavorable-chd-related-biomarkers-in-the-dongfeng-tongji-cohort
#17
Qin Fang, Zhichao Wang, Yue Zhan, Dan Li, Kun Zhang, Tao Zhou, Handong Yang, Ce Zhang, Xiulou Li, Xinwen Min, Weihong Chen, Huan Guo, Mei-An He, Weijia Kong, Tangchun Wu, Xiaomin Zhang
BACKGROUND AND AIMS: The association between hearing loss and coronary heart disease (CHD) is inconsistent. We aimed to investigate the association of hearing loss with prevalent CHD and CHD-related biomarkers among a middle aged and elderly Chinese population. METHODS: We included 14,755 Chinese aged 64.6 years from the Dongfeng-Tongji Cohort in 2013. Hearing loss was classified into normal, mild, moderate or greater levels by the pure tone average (PTA) at low frequency and high frequency, respectively...
April 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29463395/-cardiovascular-protection-of-diabetic-patient-with-chronic-renal-disease-and-particular-case-of-end-stage-renal-disease-in-elderly-patients
#18
P Zaoui, T Hannedouche, C Combe
Type 2 diabetes has an increasing prevalence. Life expectancy is dominated by cardiovascular risk, which is the leading cause of death in these patients. Up to one third of diabetic patients will develop diabetic nephropathy related to micro-angiopathy. Renal impairment further increases cardiovascular risk. Reducing cardiovascular morbidity and mortality is a major public health issue, as well as early preventing and managing chronic kidney disease (CKD). Good glycemic control prevents the micro-vascular complications of the disease (retinopathy, nephropathy, etc...
June 2017: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/29446092/association-of-salivary-lactate-dehydrogenase-level-with-systemic-inflammation-in-a-japanese-population
#19
N Miyoshi, T Tanigawa, S Nishioka, K Maruyama, E Eguchi, K Tanaka, I Saito, K Yamazaki, Y Miyake
BACKGROUND AND OBJECTIVE: Salivary lactate dehydrogenase (LDH) was reported to be a useful parameter for the screening of periodontal disease. We performed a cross-sectional study to verify the usefulness of salivary LDH as a biomarker of periodontitis and to investigate the association of severity of periodontitis with systemic inflammation by measuring salivary LDH and serum high sensitive C-reactive protein (hs-CRP) levels in a community-based middle-aged and elderly population in Japan...
February 15, 2018: Journal of Periodontal Research
https://www.readbyqxmd.com/read/29419462/gaps-in-diagnosis-and-treatment-of-cardiovascular-risk-factors-in-patients-with-psoriatic-disease-an-international-multicenter-study
#20
Lihi Eder, Paula Harvey, Vinod Chandran, Cheryl F Rosen, Jan Dutz, James T Elder, Proton Rahman, Christopher T Ritchlin, Sherry Rohekar, Richard Hayday, Snezana Barac, Joy Feld, Devy Zisman, Dafna D Gladman
OBJECTIVE: We aimed to estimate the proportion of underdiagnosis and undertreatment of cardiovascular risk factors (CVRF) in an international multicenter cohort of patients with psoriasis and psoriatic arthritis (PsA). METHODS: A cross-sectional analysis was conducted of patients with psoriatic disease from the International Psoriasis and Arthritis Research Team cohort. The presence of modifiable CVRF [diabetes, hypertension (HTN), dyslipidemia, smoking, elevated body mass index, and central obesity] and the use of appropriate therapies for HTN and dyslipidemia were determined...
March 2018: Journal of Rheumatology
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