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dyslipidemia in elderly

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https://www.readbyqxmd.com/read/29678607/association-between-hypertension-and-metabolic-disorders-among-elderly-patients-in-north-jordan
#1
Nuha Alwardat, Laura Di Renzo, Renata Costa de Miranda, Sofian Alwardat, Paola Sinibaldi Salimei, Antonino De Lorenzo
BACKGROUND: Hypertension (HTN), dyslipidemia and hyperglycemia are major risk factors for cardiovascular disease, accounting for the highest morbidity and mortality among the elderly Jordanian population. This study aimed to evaluate serum lipid and glucose profiles of hypertensive patients and normotensive controls, and determine the risk factors for HTN among elderly population in Jordan. METHODS: A cross-sectional study was carried out among 200 participants, including 111 hypertensive patients and 89 normotensive controls from June to October 2017 in North Jordan...
April 12, 2018: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/29605539/integrated-flow-mediated-vasodilation-response-predicts-cardiovascular-events-in-elderly-patients-with-cardiovascular-risk-factors-the-japan-morning-surge-home-blood-pressure-study
#2
Tomoyuki Kabutoya, Satoshi Hoshide, Kazuomi Kario
The integrated flow-mediated vasodilation (FMD) response has been associated with cardiovascular (CV) risk factors, but the association between the integrated FMD response and subsequent CV events has been unclear. We enrolled 555 patients who had at least one CV risk factor (hypertension, dyslipidemia, diabetes, or smoking). We measured the peak percentage change in diameter (ΔFMD), and integrated FMD response calculated as the area under the dilation curve over a 120-second dilation period (FMD-AUC120 )...
March 21, 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29601472/association-between-short-term-exposure-to-air-pollution-and-dyslipidemias-among-type-2-diabetic-patients-in-northwest-china-a-population-based-study
#3
Minzhen Wang, Shan Zheng, Yonghong Nie, Jun Weng, Ning Cheng, Xiaobin Hu, Xiaowei Ren, Hongbo Pei, Yana Bai
Air pollution exposure may play an adverse role in diabetes. However, little data are available directly evaluating the effects of air pollution exposure in blood lipids of which dysfunction has been linked to diabetes or its complications. We aimed to evaluate the association between air pollution and lipids level among type 2 diabetic patients in Northwest China. We performed a population-based study of 3912 type 2 diabetes patients in an ongoing cohort study in China. Both spline and multiple linear regressions analysis were used to examine the association between short-term exposure to PM10 , SO₂, NO₂ and total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C)...
March 30, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29519962/-prevention-of-dementia-with-special-reference-to-lifestyle-and-vascular-risk-factors
#4
Haruo Hanyu
There is a wide range of potentially modifiable risk factors for Alzheimer's disease and dementia, including cardiovascular risk factors (e.g. hypertension, diabetes, dyslipidemia, obesity, sleep-apnea syndrome), psychosocial factors (e.g., depression), health behaviors (e.g., low level of physical or mental activity, smoking status), and head trauma. In the elderly, weight loss associated with frailty and sarcopenia is another risk factor for dementia. Recent epidemiological studies have shown that the prevalence of dementia has declined in the US and European countries during the last 20 years...
March 2018: Brain and Nerve, Shinkei Kenkyū No Shinpo
https://www.readbyqxmd.com/read/29519347/10-year-resource-utilization-and-costs-for-cardiovascular-care
#5
Leslee J Shaw, Abhinav Goyal, Christina Mehta, Joe Xie, Lawrence Phillips, Anita Kelkar, Joseph Knapper, Daniel S Berman, Khurram Nasir, Emir Veledar, Michael J Blaha, Roger Blumenthal, James K Min, Reza Fazel, Peter W F Wilson, Matthew J Budoff
BACKGROUND: Cardiovascular disease (CVD) imparts a heavy economic burden on the U.S. health care system. Evidence regarding the long-term costs after comprehensive CVD screening is limited. OBJECTIVES: This study calculated 10-year health care costs for 6,814 asymptomatic participants enrolled in MESA (Multi-Ethnic Study of Atherosclerosis), a registry sponsored by the National Heart, Lung, and Blood Institute, National Institutes of Health. METHODS: Cumulative 10-year costs for CVD medications, office visits, diagnostic procedures, coronary revascularization, and hospitalizations were calculated from detailed follow-up data...
March 13, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29480185/designing-an-internet-based-multidomain-intervention-for-the-prevention-of-cardiovascular-disease-and-cognitive-impairment-in-older-adults-the-hatice-trial
#6
Mariagnese Barbera, Francesca Mangialasche, Susan Jongstra, Juliette Guillemont, Tiia Ngandu, Cathrien Beishuizen, Nicola Coley, Carol Brayne, Sandrine Andrieu, Edo Richard, Hilkka Soininen, Miia Kivipelto
BACKGROUND: Many dementia and cardiovascular disease (CVD) cases in older adults are attributable to modifiable vascular and lifestyle-related risk factors, providing opportunities for prevention. In the Healthy Aging Through Internet Counselling in the Elderly (HATICE) randomized controlled trial, an internet-based multidomain intervention is being tested to improve the cardiovascular risk (CVR) profile of older adults. OBJECTIVE: To design a multidomain intervention to improve CVR, based on the guidelines for CVR management, and administered through a coach-supported, interactive, platform to over 2500 community-dwellers aged 65+ in three European countries...
2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29477559/hearing-loss-is-associated-with-increased-chd-risk-and-unfavorable-chd-related-biomarkers-in-the-dongfeng-tongji-cohort
#7
Qin Fang, Zhichao Wang, Yue Zhan, Dan Li, Kun Zhang, Tao Zhou, Handong Yang, Ce Zhang, Xiulou Li, Xinwen Min, Weihong Chen, Huan Guo, Mei-An He, Weijia Kong, Tangchun Wu, Xiaomin Zhang
BACKGROUND AND AIMS: The association between hearing loss and coronary heart disease (CHD) is inconsistent. We aimed to investigate the association of hearing loss with prevalent CHD and CHD-related biomarkers among a middle aged and elderly Chinese population. METHODS: We included 14,755 Chinese aged 64.6 years from the Dongfeng-Tongji Cohort in 2013. Hearing loss was classified into normal, mild, moderate or greater levels by the pure tone average (PTA) at low frequency and high frequency, respectively...
February 22, 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29463395/-cardiovascular-protection-of-diabetic-patient-with-chronic-renal-disease-and-particular-case-of-end-stage-renal-disease-in-elderly-patients
#8
P Zaoui, T Hannedouche, C Combe
Type 2 diabetes has an increasing prevalence. Life expectancy is dominated by cardiovascular risk, which is the leading cause of death in these patients. Up to one third of diabetic patients will develop diabetic nephropathy related to micro-angiopathy. Renal impairment further increases cardiovascular risk. Reducing cardiovascular morbidity and mortality is a major public health issue, as well as early preventing and managing chronic kidney disease (CKD). Good glycemic control prevents the micro-vascular complications of the disease (retinopathy, nephropathy, etc...
June 2017: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/29446092/association-of-salivary-lactate-dehydrogenase-level-with-systemic-inflammation-in-a-japanese-population
#9
N Miyoshi, T Tanigawa, S Nishioka, K Maruyama, E Eguchi, K Tanaka, I Saito, K Yamazaki, Y Miyake
BACKGROUND AND OBJECTIVE: Salivary lactate dehydrogenase (LDH) was reported to be a useful parameter for the screening of periodontal disease. We performed a cross-sectional study to verify the usefulness of salivary LDH as a biomarker of periodontitis and to investigate the association of severity of periodontitis with systemic inflammation by measuring salivary LDH and serum high sensitive C-reactive protein (hs-CRP) levels in a community-based middle-aged and elderly population in Japan...
February 15, 2018: Journal of Periodontal Research
https://www.readbyqxmd.com/read/29419462/gaps-in-diagnosis-and-treatment-of-cardiovascular-risk-factors-in-patients-with-psoriatic-disease-an-international-multicenter-study
#10
Lihi Eder, Paula Harvey, Vinod Chandran, Cheryl F Rosen, Jan Dutz, James T Elder, Proton Rahman, Christopher T Ritchlin, Sherry Rohekar, Richard Hayday, Snezana Barac, Joy Feld, Devy Zisman, Dafna D Gladman
OBJECTIVE: We aimed to estimate the proportion of underdiagnosis and undertreatment of cardiovascular risk factors (CVRF) in an international multicenter cohort of patients with psoriasis and psoriatic arthritis (PsA). METHODS: A cross-sectional analysis was conducted of patients with psoriatic disease from the International Psoriasis and Arthritis Research Team cohort. The presence of modifiable CVRF [diabetes, hypertension (HTN), dyslipidemia, smoking, elevated body mass index, and central obesity] and the use of appropriate therapies for HTN and dyslipidemia were determined...
February 1, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29387138/tocotrienol-is-a-cardioprotective-agent-against-ageing-associated-cardiovascular-disease-and-its-associated-morbidities
#11
REVIEW
Nardev Ramanathan, Esther Tan, Li Jun Loh, Boon Seng Soh, Wei Ney Yap
Ageing is a nonmodifiable risk factor that is linked to increased likelihood of cardiovascular morbidities. Whilst many pharmacological interventions currently exist to treat many of these disorders such as statins for hypercholesterolemia or beta-blockers for hypertension, the elderly appear to present a greater likelihood of suffering non-related side effects such as increased risk of developing new onset type 2 diabetes (NODM). In some cases, lower efficacy in the elderly have also been reported. Alternative forms of treatment have been sought to address these issues, and there has been a growing interest in looking at herbal remedies or plant-based natural compounds...
2018: Nutrition & Metabolism
https://www.readbyqxmd.com/read/29376231/diabetic-retinopathy-in-the-asia-pacific
#12
REVIEW
Jacqueline Chua, Claire Xin Ying Lim, Tien Yin Wong, Charumathi Sabanayagam
Diabetic retinopathy (DR), the most common complication of diabetes mellitus, is the leading cause of new cases of blindness in middle-aged and elderly in the Asia-Pacific. It has been estimated that 51% of all those with blindness due to DR globally (n = 424,400) and 56% of those with visual impairment due to DR (2.1 million) come from the Asia-Pacific. Prevalence of DR among those with diabetes ranged from 10% in India to 43% in Indonesia within the Asia-Pacific. Awareness of DR among persons with diabetes ranged from 28% to 84%...
January 2018: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/29367900/epidemiological-analysis-of-patients-with-dupuytren-s-disease
#13
Henrique Gonçalves Mansur, Edmo Rodrigues de Oliveira, Cesar Barbosa Gonçalves
Objective: To evaluate the risk factors and analyze the characteristics of patients and lesions in Dupuytren's disease. Methods: Retrospective analysis of patients diagnosed with Dupuytren's disease in a hand surgery clinic in 2013. The authors evaluated parameters associated with the patient profiles and risk factors, the form and severity of involvement, and characteristics of the lesions. Results: 58 patients were evaluated, totaling 79 hands, with bilateral involvement in 46% of cases...
January 2018: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/29294568/-risk-and-related-factors-on-metabolic-syndrome-among-people-who-had-received-screening-on-physical-check-up-programs-in-china
#14
H Y Zhao, J Yang, F Sun, X H Yang, Z R Yang, S F Wang, S Y Zhan
Objective: To explore the risk of developing metabolic syndrome (MS) by using the data from cohorts involving people having received screening programs for physical check-up, in three areas of China (Beijing, Hongkong and Taiwan). Methods: A total number of 6 828 nonmetabolic syndromic adults, who received physical examination for the first time and with records kept for longer than 5 years (between 2004 and 2010) at the MJ centers, were recruited. Criteria developed by the Joint Committee for Developing Chinese Guidelines on Prevention and Treatment of Dyslipidemia in Chinese Adults in 2007 (JCDCG-2007) was used for defining the metabolic syndrome...
December 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/29246160/serum-lipid-profiles-in-patients-with-acute-myocardial-infarction-in-hakka-population-in-southern-china
#15
Zhixiong Zhong, Jing Liu, Bing Li, Cunren Li, Zhidong Liu, Min Yang, Qifeng Zhang, Wei Zhong, Pingsen Zhao
BACKGROUND: Little is known about serum lipid levels comparison of patients with acute myocardial infarction (AMI) in Hakka patients in southern China. To estimate the prevalence lipid profiles in Hakka patients with AMI in southern China. METHOD: We analyzed 1382 patients with a first AMI in Hakka patients in southern China between Jan. 2015 and Dec. 2015. RESULTS: Our findings demonstrated that low-density lipoprotein cholesterol (LDL), total cholesterol (TC), and triglyceride (TG) were higher in nonelderly than in elderly for males...
December 16, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/29243834/outcome-of-octogenarians-with-atrial-fibrillation-undergoing-percutaneous-coronary-intervention-insights-from-the-afcas-registry
#16
Heli M Lahtela, Aissa Bah, Tuomas Kiviniemi, Wail Nammas, Axel Schlitt, Andrea Rubboli, Pasi P Karjalainen, Marco Proietti, Juha E K Hartikainen, Gregory Y H Lip, K E Juhani Airaksinen
BACKGROUND: More evidence is needed on the optimal antithrombotic regimen in elderly patients with atrial fibrillation (AF) undergoing percutaneous coronary intervention (PCI). HYPOTHESIS: Octogenarian patients (aged ≥80 years) with AF who underwent PCI have worse 12-month clinical outcome, compared with younger patients. METHODS: We performed a post-hoc analysis of data from the prospective, multicenter AFCAS registry, which enrolled consecutive patients with AF who underwent PCI and stenting...
December 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/29212527/anemia-is-associated-with-incidence-of-dementia-a-national-health-screening-study-in-korea-involving-37-900-persons
#17
Su-Min Jeong, Dong Wook Shin, Ji Eun Lee, Jung Hyeon Hyeon, Jinkook Lee, SangYun Kim
BACKGROUND: The aim of this study was to investigate whether anemia is associated with dementia incidence in the elderly. METHODS: Using the Korean National Health Insurance Service-National Health Screening Cohort (NHIS-HEALS) database, we identified 66-year-old subjects (n = 37,900) who were free of dementia and stroke. Anemia (hemoglobin < 12 g/dl for women and < 13 g/dl for men) and the severity of anemia (mild, moderate, or severe) were defined using World Health Organization criteria...
December 6, 2017: Alzheimer's Research & Therapy
https://www.readbyqxmd.com/read/29209476/osteoarthritis-affects-health-related-quality-of-life-in-korean-adults-with-chronic-diseases-the-korea-national-health-and-nutritional-examination-surveys-2009-2013
#18
Ji Hye Yang, Kiheon Lee, Se Young Jung, Woo Kyung Bae, Hye Jin Ju, In Young Cho, Jae Kyeong Song, Hwa Yeon Park, Jong-Soo Han, Ga-Hye Lee, Ye Seul Bae
Background: Osteoarthritis (OA) is a chronic disease that commonly afflicts the elderly. This disease reduces the health-related quality of life (HRQoL) and causes a significant social burden. Whether the effect of coexisting chronic conditions on HRQoL varies according to the presence of OA remains unclear. Therefore, this study aimed to investigate this notion. Methods: A total of 13,395 participants were identified from the 2009-2013 Korean National Health and Nutrition Examination Survey for analysis...
November 2017: Korean Journal of Family Medicine
https://www.readbyqxmd.com/read/29193523/barriers-to-medication-adherence-and-links-to-cardiovascular-disease-risk-factor-control-the-framingham-heart-study
#19
Rachel Hennein, Shih-Jen Hwang, Rhoda Au, Daniel Levy, Paul Muntner, Caroline S Fox, Jiantao Ma
BACKGROUND: In the elderly, impaired cognition may weaken medication adherence and compromise treatment for cardiovascular disease (CVD). AIMS: We examined risk factors for medication adherence and the relationship between adherence and levels of CVD risk factors among older participants with hypertension, dyslipidemia, and diabetes in the Framingham Heart Study. METHODS: The four-item Morisky Medication Adherence Scale was administered to 1,559 participants, median age 70 years, 53% women...
November 30, 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/29157582/serum-lipid-profile-sleep-disordered-breathing-and-blood-pressure-in-the-elderly-a-10-year-follow-up-of-the-proof-synapse-cohort
#20
Denis Monneret, Jean-Claude Barthélémy, David Hupin, Delphine Maudoux, Sébastien Celle, Emilia Sforza, Frédéric Roche
OBJECTIVES: Dyslipidemia, sleep-disordered breathing (SDB) and hypertension are comorbid factors evidenced in adults, but poorly studied in old people. This study aimed to examine the long-term evolution of the serum lipid profile, and its relationships with SDB and blood pressure (BP) in the elderly. METHODS: A ten-year follow-up of the prospective Prognostic Indicator of Cardiovascular and Cerebrovascular Events (PROOF) and the Autonomic Nervous System Activity, Aging and Sleep Apnea/Hypopnea (SYNAPSE) cohort, which initially included 1011 elderly subjects from the general population, and who were untreated by continuous positive airway pressure (CPAP)...
November 2017: Sleep Medicine
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