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https://www.readbyqxmd.com/read/29241349/distribution-and-clustering-of-cutaneous-t-cell-lymphoma-ctcl-cases-in-canada-during-1992-to-2010
#1
Feras M Ghazawi, Elena Netchiporouk, Elham Rahme, Matthew Tsang, Linda Moreau, Steven Glassman, Nathalie Provost, Martin Gilbert, Sara-Elizabeth Jean, Osama Roshdy, Kevin Pehr, Denis Sasseville, Ivan V Litvinov
BACKGROUND: Clustering of patients with cutaneous T-cell lymphoma (CTCL) was reported in several jurisdictions around the world. This rare cancer is known to affect spouses and in some cases multiple members of the same family. These combined results suggest the existence of external disease triggers/promoters. We recently conducted the first comprehensive analysis of CTCL incidence and mortality in Canada, which revealed case clustering in several regions. OBJECTIVES: To extend our previous analysis on CTCL incidence across Canada and to provide all the collected data on CTCL patient incidence in Canada during the period of 1992 to 2010...
December 1, 2017: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29238940/seasonality-in-pediatric-cancer
#2
Rubayed Nurullah, Stefan Kuhle, Bryan Maguire, Ketan Kulkarni
Although seasonal trends in incidence and diagnosis of pediatric cancers have been widely investigated, the results have been inconclusive. A consistent seasonal trend may possibly provide etiological insights into pediatric cancers. This study aims to determine if there is a seasonal variation in cancer diagnoses in the pediatric population at the IWK Health Centre, a tertiary care center serving three Canadian provinces: Nova Scotia, New Brunswick, and Prince Edward Island. All pediatric cancer patients aged 0-20 y diagnosed from 1995 to 2015 at the center were included in this study...
December 14, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29233173/the-importance-of-health-behaviours-in-childhood-for-the-development-of-internalizing-disorders-during-adolescence
#3
Xiu Yun Wu, Sara F L Kirk, Arto Ohinmaa, Paul J Veugelers
BACKGROUND: Poor mental health constitutes a considerable global public health burden with approximately half of all cases of poor mental health having their onset before the age of 14 years. The identification of modifiable risk factors early in life is therefore essential to prevention, however, there are presently very few longitudinal studies on health behaviours for mental health to inform public health decision makers and to justify preventive action. We examined the importance of diet quality, physical activity (PA) and sedentary behaviours in childhood for internalizing disorder throughout adolescence...
December 12, 2017: BMC Psychology
https://www.readbyqxmd.com/read/29229722/doctor-who-supported-tax-reforms-removed-from-board-of-doctors-nova-scotia
#4
Roger Collier
No abstract text is available yet for this article.
December 11, 2017: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/29229610/follow-up-imaging-after-nephrectomy-for-cancer-in-canada-urologists-compliance-with-guidelines-an-observational-study
#5
Alice Dragomir, Armen Aprikian, Anil Kapoor, Antonio Finelli, Frédéric Pouliot, Ricardo Rendon, Peter C Black, Ronald Moore, Rodney H Breau, Jun Kawakami, Darrell Drachenberg, Jean-Baptiste Lattouf, Simon Tanguay
BACKGROUND: Surgical tumour removal remains the preferred treatment for most patients with renal cell carcinoma, and many medical associations have proposed guidelines for the optimal surveillance of patients following surgery. This study evaluated the adherence of Canadian urologists to the follow-up guidelines proposed by the Canadian Urological Association (CUA) in 2009. METHODS: The study cohort was identified from the Canadian Kidney Cancer Information System, a prospectively populated database from 15 academic institutions in 6 Canadian provinces: British Colombia, Alberta, Manitoba, Ontario, Quebec and Nova Scotia...
December 11, 2017: CMAJ Open
https://www.readbyqxmd.com/read/29193231/using-mri-cell-tracking-to-monitor-immune-cell-recruitment-in-response-to-a-peptide-based-cancer-vaccine
#6
Marie-Laurence Tremblay, Christa Davis, Chris V Bowen, Olivia Stanley, Cathryn Parsons, Genevieve Weir, Mohan Karkada, Marianne M Stanford, Kimberly D Brewer
PURPOSE: MRI cell tracking can be used to monitor immune cells involved in the immunotherapy response, providing insight into the mechanism of action, temporal progression of tumor growth, and individual potency of therapies. To evaluate whether MRI could be used to track immune cell populations in response to immunotherapy, CD8+ cytotoxic T cells, CD4+ CD25+ FoxP3+ regulatory T cells, and myeloid-derived suppressor cells were labeled with superparamagnetic iron oxide particles. METHODS: Superparamagnetic iron oxide-labeled cells were injected into mice (one cell type/mouse) implanted with a human papillomavirus-based cervical cancer model...
November 29, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29191182/what-systemic-factors-contribute-to-collaboration-between-primary-care-and-public-health-sectors-an-interpretive-descriptive-study
#7
Sabrina T Wong, Marjorie MacDonald, Ruth Martin-Misener, Donna Meagher-Stewart, Linda O'Mara, Ruta K Valaitis
BACKGROUND: Purposefully building stronger collaborations between primary care (PC) and public health (PH) is one approach to strengthening primary health care. The purpose of this paper is to report: 1) what systemic factors influence collaborations between PC and PH; and 2) how systemic factors interact and could influence collaboration. METHODS: This interpretive descriptive study used purposive and snowball sampling to recruit and conduct interviews with PC and PH key informants in British Columbia (n = 20), Ontario (n = 19), and Nova Scotia (n = 21), Canada...
December 1, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29109045/identification-of-the-relationship-between-barriers-and-facilitators-of-pharmacist-prescribing-and-self-reported-prescribing-activity-using-the-theoretical-domains-framework
#8
Jennifer E Isenor, Laura V Minard, Samuel A Stewart, Janet A Curran, Heidi Deal, Glenn Rodrigues, Ingrid S Sketris
BACKGROUND: The scope of pharmacist practice has expanded in many jurisdictions, including Nova Scotia, Canada, to include prescribing of medications. OBJECTIVE: To identify the relationship between barriers and facilitators to pharmacist prescribing and self-reported prescribing activity using the Theoretical Domains Framework version 2 (TDF(v2)). METHODS: The study was a self-administered electronic survey of all registered pharmacists (approximately 1300) in Nova Scotia, Canada...
October 24, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/29108689/spatial-variation-in-risk-for-physician-diagnosed-environmental-sensitivity
#9
Daniel Rainham, Patrick Brown, Tara Sampalli
Multiple chemical sensitivity (MCS) is a chronic condition characterized by recurring and severe symptoms triggered by exposures to low levels of toxicants or anthropogenic pollution. This study investigated the spatial structure of MCS incidence and estimated the contribution of socio-economic deprivation to variations in rates of MCS at the community level in Nova Scotia, Canada. Patient data were used to calculate cumulative incidence rate ratios for treated multiple chemical sensitivities. Poisson regression with a spatially autoregressive random effect was employed to assess spatial variation in MCS...
November 2017: Spatial and Spatio-temporal Epidemiology
https://www.readbyqxmd.com/read/29102923/a-traumatic-tale-of-two-cities-does-ems-level-of-care-and-transportation-model-affect-survival-in-patients-with-trauma-at-level-1-trauma-centres-in-two-neighbouring-canadian-provinces
#10
Colin Rouse, Jefferson Hayre, James French, Jacqueline Fraser, Ian Watson, Susan Benjamin, Allison Chisholm, Beth Sealy, Mete Erdogan, Robert S Green, George Stoica, Paul Atkinson
BACKGROUND: Two distinct Emergency Medical Services (EMS) systems exist in Atlantic Canada. Nova Scotia operates an Advanced Emergency Medical System (AEMS) and New Brunswick operates a Basic Emergency Medical System (BEMS). We sought to determine if survival rates differed between the two systems. METHODS: This study examined patients with trauma who were transported directly to a level 1 trauma centre in New Brunswick or Nova Scotia between 1 April 2011 and 31 March 2013...
November 4, 2017: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/29097356/development-of-a-behavior-change-intervention-to-improve-sexual-health-service-use-among-university-undergraduate-students-mixed-methods-study-protocol
#11
Christine Cassidy, Audrey Steenbeek, Donald Langille, Ruth Martin-Misener, Janet Curran
BACKGROUND: University students are at risk for acquiring sexually transmitted infections and suffering other negative health outcomes. Sexual health services offer preventive and treatment interventions that aim to reduce these infections and associated health consequences. However, university students often delay or avoid seeking sexual health services. An in-depth understanding of the factors that influence student use of sexual health services is needed to underpin effective sexual health interventions...
November 2, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/29089168/estimating-the-risk-of-bladder-and-kidney-cancer-from-exposure-to-low-levels-of-arsenic-in-drinking-water-nova-scotia-canada
#12
Nathalie Saint-Jacques, Patrick Brown, Laura Nauta, James Boxall, Louise Parker, Trevor J B Dummer
Arsenic in drinking water impacts health. Highest levels of arsenic have been historically observed in Taiwan and Bangladesh but the contaminant has been affecting the health of people globally. Strong associations have been confirmed between exposure to high-levels of arsenic in drinking water and a wide range of diseases, including cancer. However, at lower levels of exposure, especially near the current World Health Organization regulatory limit (10μg/L), this association is inconsistent as the effects are mostly extrapolated from high exposure studies...
January 2018: Environment International
https://www.readbyqxmd.com/read/29043056/genotype-by-sequencing-identifies-natural-selection-as-a-driver-of-intraspecific-divergence-in-atlantic-populations-of-the-high-dispersal-marine-invertebrate-macoma-petalum
#13
Stacy L Metivier, Jin-Hong Kim, Jason A Addison
Mitochondrial DNA analyses indicate that the Bay of Fundy population of the intertidal tellinid bivalve Macoma petalum is genetically divergent from coastal populations in the Gulf of Maine and Nova Scotia. To further examine the evolutionary forces driving this genetic break, we performed double digest genotype by sequencing (GBS) to survey the nuclear genome for evidence of both neutral and selective processes shaping this pattern. The resulting reads were mapped to a partial transcriptome of its sister species, M...
October 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28993027/methylmercury-photodemethylation-is-inhibited-in-lakes-with-high-dissolved-organic-matter
#14
Sara J Klapstein, Susan E Ziegler, Nelson J O'Driscoll
Photodemethylation can be one of the primary processes for loss of neurotoxic methylmercury (MeHg) in freshwater lakes. Few studies have quantified seasonal variations in photodemethylation rate constants as a function of dissolved organic matter (DOM). We conducted 1-week irradiation experiments in two seasons to test for spatial and temporal differences in photodemethylation potential in temperate lake waters. Six study lakes in Kejimkujik National Park, Nova Scotia were sampled in summer and fall to include a range of naturally occurring DOM concentrations (4...
October 6, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28986110/the-gulfwatch-contaminants-monitoring-program-in-the-gulf-of-maine-are-its-data-being-used-for-ocean-protection-with-special-reference-to-nova-scotia-canada
#15
Sarah D Chamberlain, Peter G Wells, Bertrum H MacDonald
The Gulfwatch Contaminants Monitoring Program is part of the Canada-US, Gulf of Maine Council on the Marine Environment (GOMC). Programs monitoring legacy toxic substances, i.e., chemical contaminants, such as Gulfwatch, collect and analyse environmental samples (e.g., blue mussels), interpret the data, and report on chemical levels and trends (spatial and temporal) in coastal waters. This study explored the extent to which its extensive information (data, reports, papers) has been used broadly and by Nova Scotia, a GOMC member...
October 3, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28983902/intractable-seizures-after-a-lengthy-remission-in-childhood-onset-epilepsy
#16
Peter R Camfield, Carol S Camfield
OBJECTIVES: To establish the risk of subsequent intractable epilepsy after ≥2, ≥5, and ≥10 years of remission in childhood-onset epilepsy. METHODS: From the Nova Scotia childhood-onset epilepsy population-based cohort patients with all types of epilepsy were selected with ≥20 years follow-up from seizure onset (incidence cases). Children with childhood absence epilepsy were excluded. The rate of subsequent intractable epilepsy was then studied for patients with ≥5 years remission on or off AED treatment and compared with the rate for those with ≥2 and ≥10 years of remission...
October 6, 2017: Epilepsia
https://www.readbyqxmd.com/read/28974280/rules-to-identify-persons-with-frailty-in-administrative-health-databases
#17
Robin Urquhart, Anik M C Giguere, Beverley Lawson, Cynthia Kendell, Jayna M Holroyd-Leduc, Joseph H Puyat, Arminee Kazanjian, Sharon Straus, Grace M Johnston
This study sought to develop frailty "identification rules" using population-based health administrative data that can be readily applied across jurisdictions for living and deceased persons. Three frailty identification rules were developed based on accepted definitions of frailty, markers of service utilization, and expert consultation, and were limited to variables within two common population-based administrative health databases: hospital discharge abstracts and physician claims data. These rules were used to identify persons with frailty from both decedent and living populations across five Canadian provinces...
October 4, 2017: Canadian Journal on Aging, la Revue Canadienne du Vieillissement
https://www.readbyqxmd.com/read/28971692/reproducing-or-reducing-inequity-considerations-for-school-food-programs
#18
Jessie-Lee D Mcisaac, Kendra Read, Patricia L Williams, Kim D Raine, Paul J Veugelers, Sara F L Kirk
It is important to consider health inequities when exploring the extent to which school food programs may contribute to the stigmatization and social exclusion of families experiencing food insecurity. As part of a broader school-based project, this paper considers evidence derived from a secondary analysis of research in Nova Scotia (NS). In the original research, interviews were conducted with key stakeholders involved in supporting health promotion activities across NS elementary schools. For this article, data were re-examined using tenets of critical discourse analysis to evaluate if school practices were addressing the root social issues by identifying patterns in language and institutional norms...
October 3, 2017: Canadian Journal of Dietetic Practice and Research
https://www.readbyqxmd.com/read/28964794/rasch-analyses-of-the-wheelchair-use-confidence-scale-for-power-wheelchair-users
#19
Brodie M Sakakibara, William C Miller, Paula W Rushton, Jan Miller Polgar
OBJECTIVE: To examine the dimensionality of the Wheelchair Use Confidence Scale for power wheelchair users (WheelCon-P); identify items that do not fit the Rasch Rating Scale model as well as redundant items for elimination; and determine the standard errors of measurement and reliability estimates for the entire range of measurements. DESIGN: Secondary analysis of cross-sectional data. SETTING: Community. PARTICIPANTS: Volunteer participants (n=189) from British Columbia, Ontario, Quebec, and Nova Scotia, Canada were recruited for this study...
September 27, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28963653/five-year-performance-monitoring-of-a-high-density-polyethylene-hdpe-cover-system-at-a-reclaimed-mine-waste-rock-pile-in-the-sydney-coalfield-nova-scotia-canada
#20
Christopher Power, Murugan Ramasamy, Devin MacAskill, Joseph Shea, Joseph MacPhee, David Mayich, Fred Baechler, Martin Mkandawire
Cover systems are commonly placed over waste rock piles (WRPs) to limit atmospheric water and oxygen ingress and control the generation and release of acid mine drainage (AMD) to the receiving environment. Although covers containing geomembranes such as high-density polyethylene (HDPE) exhibit the attributes to be highly effective, there are few, if any, published studies monitoring their performance at full-scale WRPs. In 2011, a HDPE cover was installed over the Scotchtown Summit WRP in Nova Scotia, Canada, and extensive field performance monitoring was conducted over the next five years...
September 29, 2017: Environmental Science and Pollution Research International
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