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https://www.readbyqxmd.com/read/29043056/genotype-by-sequencing-identifies-natural-selection-as-a-driver-of-intraspecific-divergence-in-atlantic-populations-of-the-high-dispersal-marine-invertebrate-macoma-petalum
#1
Stacy L Metivier, Jin-Hong Kim, Jason A Addison
Mitochondrial DNA analyses indicate that the Bay of Fundy population of the intertidal tellinid bivalve Macoma petalum is genetically divergent from coastal populations in the Gulf of Maine and Nova Scotia. To further examine the evolutionary forces driving this genetic break, we performed double digest genotype by sequencing (GBS) to survey the nuclear genome for evidence of both neutral and selective processes shaping this pattern. The resulting reads were mapped to a partial transcriptome of its sister species, M...
October 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28993027/methylmercury-photodemethylation-is-inhibited-in-lakes-with-high-dissolved-organic-matter
#2
Sara J Klapstein, Susan E Ziegler, Nelson J O'Driscoll
Photodemethylation can be one of the primary processes for loss of neurotoxic methylmercury (MeHg) in freshwater lakes. Few studies have quantified seasonal variations in photodemethylation rate constants as a function of dissolved organic matter (DOM). We conducted 1-week irradiation experiments in two seasons to test for spatial and temporal differences in photodemethylation potential in temperate lake waters. Six study lakes in Kejimkujik National Park, Nova Scotia were sampled in summer and fall to include a range of naturally occurring DOM concentrations (4...
October 6, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28986110/the-gulfwatch-contaminants-monitoring-program-in-the-gulf-of-maine-are-its-data-being-used-for-ocean-protection-with-special-reference-to-nova-scotia-canada
#3
Sarah D Chamberlain, Peter G Wells, Bertrum H MacDonald
The Gulfwatch Contaminants Monitoring Program is part of the Canada-US, Gulf of Maine Council on the Marine Environment (GOMC). Programs monitoring legacy toxic substances, i.e., chemical contaminants, such as Gulfwatch, collect and analyse environmental samples (e.g., blue mussels), interpret the data, and report on chemical levels and trends (spatial and temporal) in coastal waters. This study explored the extent to which its extensive information (data, reports, papers) has been used broadly and by Nova Scotia, a GOMC member...
October 3, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28983902/intractable-seizures-after-a-lengthy-remission-in-childhood-onset-epilepsy
#4
Peter R Camfield, Carol S Camfield
OBJECTIVES: To establish the risk of subsequent intractable epilepsy after ≥2, ≥5, and ≥10 years of remission in childhood-onset epilepsy. METHODS: From the Nova Scotia childhood-onset epilepsy population-based cohort patients with all types of epilepsy were selected with ≥20 years follow-up from seizure onset (incidence cases). Children with childhood absence epilepsy were excluded. The rate of subsequent intractable epilepsy was then studied for patients with ≥5 years remission on or off AED treatment and compared with the rate for those with ≥2 and ≥10 years of remission...
October 6, 2017: Epilepsia
https://www.readbyqxmd.com/read/28974280/rules-to-identify-persons-with-frailty-in-administrative-health-databases
#5
Robin Urquhart, Anik M C Giguere, Beverley Lawson, Cynthia Kendell, Jayna M Holroyd-Leduc, Joseph H Puyat, Arminee Kazanjian, Sharon Straus, Grace M Johnston
This study sought to develop frailty "identification rules" using population-based health administrative data that can be readily applied across jurisdictions for living and deceased persons. Three frailty identification rules were developed based on accepted definitions of frailty, markers of service utilization, and expert consultation, and were limited to variables within two common population-based administrative health databases: hospital discharge abstracts and physician claims data. These rules were used to identify persons with frailty from both decedent and living populations across five Canadian provinces...
October 4, 2017: Canadian Journal on Aging, la Revue Canadienne du Vieillissement
https://www.readbyqxmd.com/read/28971692/reproducing-or-reducing-inequity-considerations-for-school-food-programs
#6
Jessie-Lee D Mcisaac, Kendra Read, Patricia L Williams, Kim D Raine, Paul J Veugelers, Sara F L Kirk
It is important to consider health inequities when exploring the extent to which school food programs may contribute to the stigmatization and social exclusion of families experiencing food insecurity. As part of a broader school-based project, this paper considers evidence derived from a secondary analysis of research in Nova Scotia (NS). In the original research, interviews were conducted with key stakeholders involved in supporting health promotion activities across NS elementary schools. For this article, data were re-examined using tenets of critical discourse analysis to evaluate if school practices were addressing the root social issues by identifying patterns in language and institutional norms...
October 3, 2017: Canadian Journal of Dietetic Practice and Research
https://www.readbyqxmd.com/read/28964794/rasch-analyses-of-the-wheelchair-use-confidence-scale-for-power-wheelchair-users
#7
Brodie M Sakakibara, William C Miller, Paula W Rushton, Jan Miller Polgar
OBJECTIVE: To examine the dimensionality of the Wheelchair Use Confidence Scale for power wheelchair users (WheelCon-P); identify items that do not fit the Rasch Rating Scale model as well as redundant items for elimination; and determine the standard errors of measurement and reliability estimates for the entire range of measurements. DESIGN: Secondary analysis of cross-sectional data. SETTING: Community. PARTICIPANTS: Volunteer participants (n=189) from British Columbia, Ontario, Quebec, and Nova Scotia, Canada were recruited for this study...
September 27, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28963653/five-year-performance-monitoring-of-a-high-density-polyethylene-hdpe-cover-system-at-a-reclaimed-mine-waste-rock-pile-in-the-sydney-coalfield-nova-scotia-canada
#8
Christopher Power, Murugan Ramasamy, Devin MacAskill, Joseph Shea, Joseph MacPhee, David Mayich, Fred Baechler, Martin Mkandawire
Cover systems are commonly placed over waste rock piles (WRPs) to limit atmospheric water and oxygen ingress and control the generation and release of acid mine drainage (AMD) to the receiving environment. Although covers containing geomembranes such as high-density polyethylene (HDPE) exhibit the attributes to be highly effective, there are few, if any, published studies monitoring their performance at full-scale WRPs. In 2011, a HDPE cover was installed over the Scotchtown Summit WRP in Nova Scotia, Canada, and extensive field performance monitoring was conducted over the next five years...
September 29, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28962593/examining-the-provisional-guidelines-for-weight-gain-in-twin-pregnancies-a-retrospective-cohort-study
#9
Olha Lutsiv, Adam Hulman, Christy Woolcott, Joseph Beyene, Lucy Giglia, B Anthony Armson, Linda Dodds, Binod Neupane, Sarah D McDonald
BACKGROUND: Weight gain during pregnancy has an important impact on maternal and neonatal health. Unlike the Institute of Medicine (IOM) recommendations for weight gain in singleton pregnancies, those for twin gestations are termed "provisional", as they are based on limited data. The objectives of this study were to determine the neonatal and maternal outcomes associated with gaining weight below, within and above the IOM provisional guidelines on gestational weight gain in twin pregnancies, and additionally, to explore ranges of gestational weight gain among women who delivered twins at the recommended gestational age and birth weight, and those who did not...
September 29, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28956294/the-impact-of-us-fda-and-health-canada-warnings-related-to-the-safety-of-high-dose-simvastatin
#10
Kanika Anand, Ingrid Sketris, Ying Zhang, Adrian Levy, John-Michael Gamble
INTRODUCTION: Between 2010 and 2012, the US Food and Drug Administration and Health Canada issued warnings to healthcare professionals emphasizing the increased risk of muscle problems with high-dose simvastatin. OBJECTIVE: To measure the impact of the Health Canada safety warning regarding dose-dependent adverse effects of simvastatin on prescribing of low, medium, and high doses of simvastatin. METHODS: An interrupted time-series design was used to evaluate the impact of a Health Canada safety warning on 7 November 2012 regarding the safety of high-dose simvastatin...
September 27, 2017: Drugs—Real World Outcomes
https://www.readbyqxmd.com/read/28930950/increased-mortality-in-trauma-patients-who-develop-postintubation-hypotension
#11
Robert S Green, Michael B Butler, Mete Erdogan
BACKGROUND: Postintubation hypotension (PIH) is common and associated with poor outcomes in critically ill patient populations requiring emergency endotracheal intubation (ETI). The importance of PIH in the trauma population remains unclear. The objective of this study was to determine the prevalence of PIH in trauma patients and assess the association of PIH with patient outcomes. METHODS: Retrospective case series of adult (≥16 years) patients who were intubated on arrival at a tertiary trauma center in Halifax, Nova Scotia, Canada, between 2000 and 2015...
October 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28929886/water-recycling-at-the-nova-scotia-hospital-central-laundry
#12
David Bligh, Dylan Dingwell
A water recycling system was installed at the Nova Scotia Hospital Central Laundry in Dartmouth, Nova Scotia in the spring of 2014. The consequent reductions in the consumption of water and steam at this facility have been measured over a 20-month period and are presented here in nominal units and as a financial analysis. Cumulative savings over this period have been calculated to be $351,567, representing a 53% annual return on investment after accounting for annual operating and maintenance costs.
March 2017: Healthcare Management Forum
https://www.readbyqxmd.com/read/28929853/physician-leadership-development-evidence-informed-design-tempered-with-real-life-experience
#13
Shawn Jolemore, Steven D Soroka
This article describes key considerations for creation of evidence-informed in-house physician leadership development. Ten elements extracted from a scan of the peer-reviewed and grey literature are presented, and key learnings at the Queen Elizabeth II Health Sciences Centre, a quaternary academic health sciences centre in Halifax, Nova Scotia, are highlighted. Each element is briefly described with practical considerations and challenges to implementation outlined in the context of the former Capital District Health Authority, where the authors collaborated to create in-house physician leadership development prior to the consolidation of health districts in that province...
May 2017: Healthcare Management Forum
https://www.readbyqxmd.com/read/28927481/a-system-wide-solution-to-antidote-stocking-in-emergency-departments-the-nova-scotia-antidote-program
#14
Nancy G Murphy, D Ruth Bona, Theresa A Hurley
OBJECTIVE: Inadequate stocking of essential antidotes in hospitals is an internationally documented problem. A concrete and sustainable system-wide solution for easy access to antidotes in emergency departments (EDs) was developed and implemented in Nova Scotia, Canada. METHODS: Antidote stocking guidelines and a systemwide antidote management strategy were established. A standardized collection of antidotes housed in highly visible containers in provincial EDs was implemented for timely access...
September 20, 2017: CJEM
https://www.readbyqxmd.com/read/28853970/primary-care-physicians-views-about-prescribing-methadone-to-treat-opioid-use-disorder
#15
James D Livingston, Erica Adams, Marlee Jordan, Zachary MacMillan, Ramm Hering
BACKGROUND: Methadone maintenance treatment is an effective way to reduce harms associated with opioid use disorder and, in several countries, is delivered in community-based primary care settings. Expanding methadone into primary care depends, in part, on physicians' willingness and readiness to integrate it into their practices. OBJECTIVES: This qualitative study explores factors that primary care physicians consider important when contemplating prescribing methadone to treat opioid use disorder...
August 30, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28822778/diabetes-care-program-of-nova-scotia-celebrating-25-years-of-improving-diabetes-care-in-nova-scotia
#16
REVIEW
Jennifer I Payne, Margaret J Dunbar, Pamela Talbot, Meng H Tan
The Diabetes Care Program of Nova Scotia (DCPNS)'s mission is "to improve, through leadership and partnerships, the health of Nova Scotians living with, affected by, or at risk of developing diabetes." Working together with local, provincial and national partners, the DCPNS has improved and standardized diabetes care in Nova Scotia over the past 25 years by developing and deploying a resourceful and collaborative program model. This article describes the model and highlights its key achievements. With balanced representation from frontline providers through to senior decision makers in health care, the DCPNS works across the age continuum, supporting the implementation of national clinical practice guidelines and, when necessary, developing provincial guidelines to meet local needs...
August 16, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28812833/evaluating-the-implementation-and-feasibility-of-a-web-based-tool-to-support-timely-identification-and-care-for-the-frail-population-in-primary-healthcare-settings
#17
Beverley Lawson, Tara Sampalli, Stephanie Wood, Grace Warner, Paige Moorhouse, Rick Gibson, Laurie Mallery, Fred Burge, Lisa G Bedford
BACKGROUND: Understanding and addressing the needs of frail persons is an emerging health priority for Nova Scotia and internationally. Primary healthcare (PHC) providers regularly encounter frail persons in their daily clinical work. However, routine identification and measurement of frailty is not standard practice and, in general, there is a lack of awareness about how to identify and respond to frailty. A web-based tool called the Frailty Portal was developed to aid in identifying, screening, and providing care for frail patients in PHC settings...
March 7, 2017: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/28811876/individual-quality-and-age-but-not-environmental-or-social-conditions-modulate-costs-of-reproduction-in-a-capital-breeder
#18
Lucie Debeffe, Jocelyn Poissant, Philip D McLoughlin
Costs associated with reproduction are widely known to play a role in the evolution of reproductive tactics with consequences to population and eco-evolutionary dynamics. Evaluating these costs as they pertain to species in the wild remains an important goal of evolutionary ecology. Individual heterogeneity, including differences in individual quality (i.e., among-individual differences in traits associated with survival and reproduction) or state, and variation in environmental and social conditions can modulate the costs of reproduction; however, few studies have considered effects of these factors simultaneously...
August 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28799783/gluten-free-foods-in-rural-maritime-provinces-limited-availability-high-price-and-low-iron-content
#19
Jennifer A Jamieson, Laura Gougeon
We investigated the price difference between gluten-free (GF) and gluten-containing (GC) foods available in rural Maritime stores. GF foods and comparable GC items were sampled through random visits to 21 grocery stores in nonurban areas of Nova Scotia, New Brunswick, and Prince Edward Island, Canada. Wilcoxon rank tests were conducted on price per 100 g of product, and on the price relative to iron content; 2226 GF foods (27.2% staple items, defined as breads, cereals, flours, and pastas) and 1625 GC foods were sampled, with an average ± SD of 66 ± 2...
August 11, 2017: Canadian Journal of Dietetic Practice and Research
https://www.readbyqxmd.com/read/28794620/spreading-improvements-for-advanced-copd-care-through-a-canadian-collaborative
#20
Graeme M Rocker, Claudia Amar, Wendy L Laframboise, Jane Burns, Jennifer Y Verma
BACKGROUND: A year-long pan-Canadian quality improvement collaborative (QIC) led by the Canadian Foundation for Healthcare Improvement (CFHI) supported the spread of the successful Halifax, Nova Scotia-based INSPIRED COPD Outreach Program™ to 19 teams in the 10 Canadian provinces. We describe QIC results, addressing two main questions: 1) Can the results of the Nova Scotia INSPIRED model be replicated elsewhere in Canada? 2) How did the teams implement and evaluate their versions of the INSPIRED program? METHODS: Collaborative faculty selected measures that were evidence-based, relatively simple to collect, and relevant to local context...
2017: International Journal of Chronic Obstructive Pulmonary Disease
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