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https://www.readbyqxmd.com/read/29351047/otologic-disease-following-palatoplasty-in-international-cleft-palate-cohort
#1
Jeff Markey, Rebecca Maine, Kimberly Daniels, Emily Yang Yu, George Gregory, William Hoffman, Jorge Palacios
OBJECTIVE: Study the prevalence of otologic disease in a pediatric post-palatoplasty population with no prior ear tube placement in resource-deprived countries and assess patient characteristics associated with these abnormal results. DESIGN: Retrospective data review. PARTICIPANTS: Ecuadorian and Chinese children identified during humanitarian cleft lip and palate repair trips with cleft palates undergoing palatoplasty from 2007 to 2010. INTERVENTIONS: Tympanometry and otoacoustic emission (OAE) testing performed following palatoplasty...
February 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29344786/colonoscopy-induced-acute-diverticulitis-myth-or-reality
#2
Emre Gorgun, Ozgen Isik, Ipek Sapci, Erman Aytac, Maher A Abbas, Gokhan Ozuner, James Church, Scott R Steele
BACKGROUND: Colonoscopy in patients with diverticulosis can be technically challenging and limited data exist relating to the risk of post-colonoscopy diverticulitis. Our aim was to evaluate the incidence, management, and outcomes of acute diverticulitis following colonoscopy. METHODS: Study design is retrospective cohort study. Data were gathered by conducting an automated search of the electronic patient database using current procedural terminology and ICD-9 codes...
January 17, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29342320/association-of-pre-esrd-serum-calcium-with-post-esrd-mortality-among-incident-esrd-patients-a-cohort-study
#3
Yoshitsugu Obi, Christina Park, Melissa Soohoo, Keiichi Sumida, Takayuki Hamano, Connie M Rhee, Csaba P Kovesdy, Kamyar Kalantar-Zadeh, Elani Streja
Albumin-corrected serum calcium (cSCa) decline at late stages of chronic kidney disease and rise after dialysis initiation. While hypercalcemia is associated with higher mortality in end-stage renal disease (ESRD), there are scarce data on the impact of pre-ESRD cSCa on post-ESRD mortality. Therefore, we used a large national cohort of 21,826 US veterans with incident ESRD who transitioned to dialysis in all US Department of Veterans Affairs healthcare facilities over 2009-2014 to examine the associations with all-cause and cause-specific post-ESRD mortality of (1) cSCa concentrations averaged over the last six months and (2) its rate of decline during the last 12 months before dialysis initiation...
January 17, 2018: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29340295/usage-characteristics-and-adverse-event-rates-%C3%A2-of-the-direct-puncture-and-pull-techniques-for-percutaneous-endoscopic-gastrostomy-in-patients-with-malignant-tumors-of-the-upper-aerodigestive-tract
#4
Niels Teich, Lars Selig, Susanne Liese, Franziska Schiefke, Alexander Hemprich, Joachim Mössner, Ingolf Schiefke
Background and study aims:  Patients with malignant tumors of the upper gastrointestinal tract are at risk of weight loss. Early supportive nutrition therapy is therefore recommended and usually requires placement of a percutaneous endoscopic gastrostomy (PEG). The aim of this study was to compare adverse events and usage characteristics of the direct puncture technique with those of the traditional pull technique when used in patients with endoscopically passable tumors. The primary endpoint was the rate of inflammatory adverse events (AEs) at the gastrostomy fistula...
January 2018: Endoscopy International Open
https://www.readbyqxmd.com/read/29335321/effectiveness-and-cost-of-weekly-recombinant-tissue-plasminogen-activator-hemodialysis-catheter-locking-solution
#5
Brenda R Hemmelgarn, Braden J Manns, Steven D Soroka, Adeera Levin, Jennifer MacRae, Karthik Tennankore, Jo-Anne S Wilson, Robert G Weaver, Pietro Ravani, Robert R Quinn, Marcello Tonelli, Mercedeh Kiaii, Paula Mossop, Nairne Scott-Douglas
BACKGROUND AND OBJECTIVES: Evidence to guide hemodialysis catheter locking solutions is limited. We aimed to assess effectiveness and cost of recombinant tissue plasminogen activator (rt-PA) once per week as a locking solution, compared with thrice weekly citrate or heparin, in patients at high risk of complications. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We used a prospective design and pre-post comparison in three sites across Canada. Pre-post comparisons were conducted using multilevel mixed effects regression models accounting for cluster with site and potential enrollment of patients more than once...
January 15, 2018: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/29333073/the-impact-of-age-on-the-incidence-and-severity-of-post-endoscopic-retrograde-cholangiopancreatography-pancreatitis
#6
Panagiotis Katsinelos, Georgia Lazaraki, Grigoris Chatzimavroudis, Sotiris Terzoudis, Anthi Gatopoulou, Andreas Xanthis, Sotiris Anastasiadis, Kiriaki Anastasiadou, Nikos Georgakis, Dimitris Tzivras, Jannis Kountouras
Background: With advancing age there is progressive pancreatic atrophy and fibrosis, leading to tissue destruction and chronic pancreatitis that has been found to be protective against post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP). However, there are no reports regarding the potential effect of the aging pancreatic changes on the incidence and severity of PEP. Therefore, the aim of the present study was to investigate the impact of senile changes in the pancreas on the incidence and severity of PEP...
January 2018: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/29314655/randomised-controlled-trial-of-standard-closure-of-stoma-site-versus-biologic-mesh-reinforcement-study-protocol-of-the-rocss-trial
#7
(no author information available yet)
BACKGROUND: Closure of complex and contaminated abdominal wounds is challenging and carries risks, including wound dehiscence and incisional hernias. Hernia formation at closed stoma sites occurs in up to 30% of patients. Use of biological meshes in these situations may provide a safe method of reducing these complications, especially long-term incisional hernias. METHOD: The Reinforcement of Closure of Stoma Site (ROCSS) study is a phase III multicentre randomised controlled trial (RCT), with an internal feasibility study...
January 3, 2018: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/29312646/predictive-value-of-post-procedural-early-within-24-h-increase-in-cystatin-c-for-contrast-induced-acute-kidney-injury-and-mortality-following-coronary-angiography-or-intervention
#8
Yong Liu, Kai-Hong Chen, Shi-Qun Chen, Li-Ling Chen, Chong-Yang Duan, Kun Wang, Xiao-Sheng Guo, Hua-Long Li, Wei-Jie Bei, Kai-Yan Lin, Ping-Yan Chen, Ying Xian, Ning Tan, Ying-Ling Zhou, Qing-Shan Geng, Ji-Yan Chen
Objective: To investigate the predictive value of post-procedural early (within 24 h) increase in cystatin C for contrast-induced acute kidney injury (CI-AKI) and all-cause mortality following coronary angiography or intervention. Methods: We prospectively investigated 1042 consecutive patients with both baseline and early post-procedural cystatin C measurement undergoing coronary angiography or intervention. CI-AKI was defined as an increase ≥0.3 mg/dL or >50% in serum creatinine from baseline within 48 h post-procedure...
December 12, 2017: Oncotarget
https://www.readbyqxmd.com/read/29306610/hypoglycemia-during-oral-glucose-tolerance-test-among-post-bariatric-surgery-pregnant-patients-incidence-and-perinatal-significance
#9
Amihai Rottenstreich, Ram Elazary, Yossef Ezra, Geffen Kleinstern, Nahum Beglaibter, Uriel Elchalal
BACKGROUND: While hypoglycemia during an oral glucose tolerance test (OGTT) has been shown to occur in a considerable portion of nonpregnant post-bariatric surgery (BS) patients, its incidence among pregnant post-BS patients evaluated for gestational diabetes has only been sparsely studied. OBJECTIVES: We investigated OGTT results and pregnancy outcomes in pregnant women who underwent 3 types of bariatric procedures before pregnancy. SETTING: A university hospital...
December 8, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29306469/value-of-dapt-score-to-predict-adverse-outcome-in-patients-with-atrial-fibrillation-undergoing-percutaneous-coronary-intervention-a-post-hoc-analysis-from-the-afcas-registry
#10
Wail Nammas, Tuomas Kiviniemi, Axel Schlitt, Andrea Rubboli, Josè Valencia, Gregory Y H Lip, Pasi P Karjalainen, Fausto Biancari, K E Juhani Airaksinen
BACKGROUND: The DAPT score identifies patients with expected benefit from extended dual antiplatelet therapy beyond 1year after percutaneous coronary intervention (PCI). In a post-hoc analysis from the AFCAS registry, we explored the value of DAPT score to predict outcome in patients with atrial fibrillation (AF) undergoing PCI. METHODS AND RESULTS: Outcome measures included major adverse cardiac/cerebrovascular events (MACCE) [all-cause death, myocardial infarction, repeat revascularization, stent thrombosis, or stroke/transient ischemic attack] and bleeding events...
February 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29305152/preventing-depression-in-the-offspring-of-parents-with-depression-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#11
REVIEW
Johanna Loechner, Kornelija Starman, Katharina Galuschka, Jeanette Tamm, Gerd Schulte-Körne, Julian Rubel, Belinda Platt
One major predictor of depression onset is having a depressed parent. This study provides the first systematic review and meta-analysis of preventive interventions for offspring of depressed parents. We searched six literature databases and included randomized controlled trials which concerned the non-depressed offspring (aged 18 or younger) of a depressed parent, who received a preventive intervention designed to reduce the risk of depression or a comparison condition. Primary and secondary outcome measures were the severity and incidence of childhood depression...
November 29, 2017: Clinical Psychology Review
https://www.readbyqxmd.com/read/29301463/hospitalization-associated-disability-in-older-adults-with-valvular-heart-disease-incidence-risk-factors-and-its-association-with-care-processes
#12
Maren Jonckers, Bastiaan Van Grootven, Ester Willemyns, Miek Hornikx, Anthony Jeuris, Christophe Dubois, Marie-Christine Herregods, Mieke Deschodt
BACKGROUND: The aim of this study was to determine the incidence and recovery of hospitalisation-associated disability (HAD), the associated risk factors, and the link with care processes in patients aged 70 years or older hospitalised with valvular heart disease (VHD). METHODS: Prospective cohort study performed on the cardiology and cardiac surgery units of University Hospitals Leuven, Belgium. HAD was defined as the loss of independence to complete one of the Activities of Daily Living (ADLs) between hospital admission and discharge...
January 4, 2018: Acta Cardiologica
https://www.readbyqxmd.com/read/29299482/have-the-annual-trends-of-total-hip-arthroplasty-in-rheumatoid-arthritis-patients-decreased
#13
Kemjika O Onuoha, Max Solow, Jared M Newman, Nipun Sodhi, Robert Pivec, Anton Khlopas, Assem A Sultan, Morad Chughtai, Neil V Shah, Jaiben George, Michael A Mont
Background: Rheumatoid arthritis (RA) is characterized by chronic systemic and synovial inflammation, resulting in damage to both cartilage and bone. Medical treatment, which has increasingly relied upon disease modifying anti-rheumatic drugs (DMARDs), may fail to slow disease progression and limit joint damage, ultimately warranting surgical intervention. Up to 25% of RA patients will require lower extremity total joint arthroplasty. Though total hip arthroplasty (THA) is known to improve quality of life and functional measures, clarification is still required with respect to the impact of increased DMARD use on annual rates of THA...
December 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/29297765/evaluation-of-a-multi-layered-health-promotion-approach-in-rural-china
#14
Xiangyang Tian, Liping Yan, Genming Zhao, Liang Wang, Yulan Cheng, Yong Lu, Jodi Southerland
BACKGROUND: To explore the effectiveness of a multi-layered health promotion approach in rural China. METHODS: A two-year intervention was applied to the 18 intervention rural villages while the 18 controls received standard health communication materials. Data were collected at baseline and post-intervention respectively to evaluate the effectiveness. RESULTS: All intervention villages had developed healthy policies addressing prioritized health issues such as livestock captivity, garbage disposal, etc...
January 1, 2018: Global Health Promotion
https://www.readbyqxmd.com/read/29296770/osteonecrosis-of-the-femoral-head-in-sickle-cell-disease-prevalence-comorbidities-and-surgical-outcomes-in-california
#15
Oyebimpe Adesina, Ann Brunson, Theresa H M Keegan, Ted Wun
Osteonecrosis of the femoral head (ONFH) is a prevalent complication of sickle cell disease (SCD) that has not been well described in population-based cohort studies. Using California's Office of Statewide Planning and Development discharge databases (1991-2013), we estimated the cumulative incidence of ONFH after accounting for the competing risk of death and used a multivariable Cox proportional hazards regression to identify factors associated with ONFH diagnosis. We also calculated rates of readmissions to the hospital or emergency department within 30 to 90 days of hip replacement surgery...
July 11, 2017: Blood Advances
https://www.readbyqxmd.com/read/29289343/rates-and-trends-for-inpatient-surgeries-in-pediatric-crohn-s-disease-in-the-united-states-from-2003-to-2012
#16
Audrey L Stokes, Afif N Kulaylat, Dorothy V Rocourt, Christopher S Hollenbeak, Walter Koltun, Tolulope Falaiye
BACKGROUND: Pediatric Crohn's disease (CD) is increasing in incidence globally. Trends in specific types of inpatient pediatric CD-related surgical procedures have not been widely reported. METHODS: Patients ≤20 years of age with CD were identified in the Kids' Inpatient Database for 2003, 2006, 2009, and 2012. Bowel resection, stoma creation, and perianal or percutaneous drainage procedures were identified using ICD-9 procedure codes, and trends were identified...
December 5, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29288116/a-study-on-outcome-of-binding-pancreaticogastrostomy-following-pancreaticoduodenectomy-a-prospective-study
#17
Dronacharya Routh, Nishant Pathak, C S Naidu, A K Singh, P P Rao, Priya Ranjan
INTRODUCTION: The type of anastomosis of the pancreas following pancreaticoduodenectomy is often attributed to the reason for pancreatic leak. Results of various randomized trials comparing pancreaticojejunostomy and pancreaticogastrostomy are conflicting one suggesting advantage over the other and vice versa. In this study we intend to critically analyze a novel technique of binding pancreaticogastrostomy following pancreaticoduodenectomy. AIMS AND OBJECTIVES: The aim of this study is to see the outcome of binding pancreaticogastrostomy by evaluating the technical aspects of binding PG and study the incidence of post-operative complications...
December 26, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/29287882/changes-in-the-epidemiology-and-clinical-features-of-acute-mastoiditis-following-the-introduction-of-the-pneumococcal-conjugate-vaccine
#18
Oren Cavel, Riva Tauman, Eli Simsolo, Danny Yafit, Efrat Reindorf-Kfir, Oshri Wasserzug, Omer Unger, Ophir Handzel, Gadi Fishman, Yael Oestreicher-Kedem, Ari DeRowe
OBJECTIVES: Seven years after the introduction of the pneumococcal conjugate vaccines (PCV) in Israel, its effect on the incidence and severity of episodes of acute mastoiditis (AM) remains unclear. The primary objective of this study was to determine the incidence of AM and describe its clinical features in children during the years that followed the introduction of the PCV13 in comparison with the pre-PCV period. METHODS: Included in this retrospective comparative case series were all pediatric patients diagnosed with AM between Jan...
January 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29287870/postoperative-bradycardia-following-adenotonsillectomy-in-children-does-intraoperative-administration-of-dexmedetomidine-play-a-role
#19
Benjamin Bush, Joseph D Tobias, Chen Lin, James Ruda, Kris R Jatana, Garth Essig, Jennifer Cooper, Dmitry Tumin, Charles A Elmaraghy
INTRODUCTION: Dexmedetomidine is a novel pharmacologic agent that has become a frequently used adjunct during care of pediatric patients with obstructive sleep apnea (OSA) undergoing tonsillectomy. While generally safe and effective, dexmedetomidine is associated with adverse effects of hypotension and bradycardia from its central sympatholytic effects. Due to safety concerns, our institution routinely admits patients with OSA for overnight cardiorespiratory monitoring following tonsillectomy...
January 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29286319/cellular-and-molecular-mechanisms-underlying-non-pharmaceutical-ischemic-stroke-therapy-in-aged-subjects
#20
REVIEW
Raluca Elena Sandu, Danut Dumbrava, Roxana Surugiu, Daniela-Gabriela Glavan, Andrei Gresita, Eugen Bogdan Petcu
The incidence of ischemic stroke in humans increases exponentially above 70 years both in men and women. Comorbidities like diabetes, arterial hypertension or co-morbidity factors such as hypercholesterolemia, obesity and body fat distribution as well as fat-rich diet and physical inactivity are common in elderly persons and are associated with higher risk of stroke, increased mortality and disability. Obesity could represent a state of chronic inflammation that can be prevented to some extent by non-pharmaceutical interventions such as calorie restriction and hypothermia...
December 29, 2017: International Journal of Molecular Sciences
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