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Critical Incident Response

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https://www.readbyqxmd.com/read/27904455/profiling-of-disease-related-metabolites-in-grapevine-internode-tissues-infected-with-agrobacterium-vitis
#1
Sung-Min Jung, Youn-Young Hur, John E Preece, Oliver Fiehn, Young-Ho Kim
Green shoot cuttings of 10 different grapevine species were inoculated with Agrobacterium vitis to find disease-related metabolites in the grapevine. Crown galls formed 60 days after inoculation varied in gall severity (GS) evaluated by gall incidence (GI) and gall diameter (GD), which were classified into three response types as RR (low GI and small GD), SR (high GI and small GD), and SS (high GI and large GD), corresponding to resistant, moderately resistant, and susceptible responses, respectively. In this, 4, 4, and 2 Vitis species were classified into RR, SR, and SS, respectively...
December 2016: Plant Pathology Journal
https://www.readbyqxmd.com/read/27894557/reporting-helicopter-emergency-medical-services-in-major-incidents-a-delphi-study
#2
Sabina Fattah, Anne Siri Johnsen, Stephen J M Sollid, Torben Wisborg, Marius Rehn, Ákos Sóti, Anatolij Truhlář, Andreas J Krüger, Björn Gunnarsson, Dan Gryth, David Ohlén, Espen Fevang, Geir Arne Sunde, Ivo Breitenmoser, Jouni Kurola, Jouni Nurmi, Knut Fredriksen, Leif Rognås, Peter Temesvari, Søren Mikkelsen, Vidar Magnusson, Wolfgang Voelckel
OBJECTIVE: Research on helicopter emergency medical services (HEMS) in major incidents is predominately based on case descriptions reported in a heterogeneous fashion. Uniform data reported with a consensus-based template could facilitate the collection, analysis, and exchange of experiences. This type of database presently exists for major incident reporting at www.majorincidentreporting.net. This study aimed to develop a HEMS-specific major incident template. METHODS: This Delphi study included 17 prehospital critical care physicians with current or previous HEMS experience...
November 2016: Air Medical Journal
https://www.readbyqxmd.com/read/27888679/continuing-rise-in-oropharyngeal-cancer-in-a-high-hpv-prevalence-area-a-danish-population-based-study-from-2011-to-2014
#3
Amanda-Louise Fenger Carlander, Christian Grønhøj Larsen, David Hebbelstrup Jensen, Emilie Garnæs, Katalin Kiss, Luise Andersen, Caroline Holkmann Olsen, Maria Franzmann, Estrid Høgdall, Susanne K Kjær, Bodil Norrild, Lena Specht, Elo Andersen, Thomas van Overeem Hansen, Finn Cilius Nielsen, Christian von Buchwald
BACKGROUND: Human papillomavirus (HPV) is a critical element in the rising incidence of oropharyngeal squamous cell carcinoma (OPSCC), although whether this trend will continue, and the types of HPV responsible, are currently unknown. We previously demonstrated an increased incidence of HPV-related OPSCC in the high HPV prevalence area of Eastern Denmark from 2000 to 2010. Therefore, we investigated if the incidence for OPSCC continued to rise, the association to HPV and putative HPV-types in Eastern Denmark from 2011 to 14...
November 23, 2016: European Journal of Cancer
https://www.readbyqxmd.com/read/27888555/renal-operational-tolerance-is-associated-with-a-defect-of-blood-tfh-cells-that-exhibit-impaired-b-cell-help
#4
Alexis Chenouard, Mélanie Chesneau, Linh Bui Nguyen, Sabine Le Bot, Marion Cadoux, Emilie Dugast, Chloé Paul, Stéphanie Malard-Castagnet, Simon Ville, Pierrick Guérif, Jean-Paul Soulillou, Nicolas Degauque, Richard Danger, Magali Giral, Sophie Brouard
Renal operationally tolerant patients (TOL) display a defect in B cell differentiation, with a deficiency in plasma cells. Recently described, T follicular helper cells (Tfh) play a critical role in B cell differentiation. We analyzed blood Tfh subsets in TOL and transplanted patients with stable graft function under immunosuppression (STA). We observed a reduced proportion of blood activated and highly functional Tfh subsets in TOL, without affecting Tfh absolute numbers. Functionally, Tfh from TOL displayed a modified gene expression profile, failed to produce IL-21 and were unable to induce IgG production by naive B cells...
November 26, 2016: American Journal of Transplantation
https://www.readbyqxmd.com/read/27875057/national-athletic-trainers-association-position-statement-preventing-and-managing-sport-related-dental-and-oral-injuries
#5
Trenton E Gould, Scott G Piland, Shane V Caswell, Dennis Ranalli, Stephen Mills, Michael S Ferrara, Ron Courson
OBJECTIVE:  To provide athletic trainers, health care professionals, and all those responsible for the care of athletes with clinical recommendations for preventing and managing sport-related dental and oral injuries. BACKGROUND:  Participation in competitive sports continues to grow at both the interscholastic and intercollegiate levels. Therefore, exposure to, and the incidence of athletic-related injury, including orofacial injury, will also likely increase...
November 22, 2016: Journal of Athletic Training
https://www.readbyqxmd.com/read/27870718/self-reported-preparedness-to-respond-to-mass-fatality-incidents-in-38-state-health-departments
#6
Jacqueline Merrill, Qi Zhi, Robyn R Gershon
CONTEXT: Public health departments play an important role in the preparation and response to mass fatality incidents (MFIs). OBJECTIVE: To describe MFI response capabilities of US state health departments. DESIGN: The data are part of a multisector cross-sectional study aimed at 5 sectors that comprise the US mass fatality infrastructure. Data were collected over a 6-week period via a self-administered, anonymous Web-based survey. SETTING: In 2014, a link to the survey was distributed via e-mail to health departments in 50 states and the District of Columbia...
January 2017: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/27870460/sex-differences-in-the-immune-response-to-experimental-stroke-implications-for-translational-research
#7
REVIEW
Abby L Dotson, Halina Offner
Ischemic stroke is a leading cause of death and disability in the United States. It is known that males and females respond differently to stroke. Depending on age, the incidence, prevalence, mortality rate, and disability outcome of stroke differ between the sexes. Females generally have strokes at older ages than males and, therefore, have a worse stroke outcome. There are also major differences in how the sexes respond to stroke at the cellular level. Immune response is a critical factor in determining the progress of neurodegeneration after stroke and is fundamentally different for males and females...
January 2, 2017: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/27870410/sex-differences-in-neuroinflammation-and-neuroprotection-in-ischemic-stroke
#8
REVIEW
Monica S Spychala, Pedram Honarpisheh, Louise D McCullough
Stroke is not only a leading cause of mortality and morbidity worldwide it also disproportionally affects women. There are currently over 500,000 more women stroke survivors in the US than men, and elderly women bear the brunt of stroke-related disability. Stroke has dropped to the fifth leading cause of death in men, but remains the third in women. This review discusses sex differences in common stroke risk factors, the efficacy of stroke prevention therapies, acute treatment responses, and post-stroke recovery in clinical populations...
January 2, 2017: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/27849332/pulmonary-microvascular-dysfunction-and-pathological-changes-induced-by-blast-injury-in-a-rabbit-model
#9
Si Yu Wu, Geng Fen Han, Jian Yi Kang, Liang Chao Zhang, Ai Min Wang, Jian Min Wang
BACKGROUND: Vascular leakage has been proven to play a critical role in the incidence and development of explosive pulmonary barotrauma. Quantitatively investigated in the present study was the severity of vascular leakage in a gradient blast injury series, as well as ultrastructural evidence relating to pulmonary vascular leakage. METHODS: One hundred adult male New Zealand white rabbits were randomly divided into 5 groups according to distance from the detonator (10 cm, 15 cm, 20 cm, 30 cm, and sham control)...
September 2016: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/27848403/reasons-for-delayed-patient-discharge-following-day-surgery-a-literature-review
#10
Alison Rae
Aim The aim of this literature review was to explore the reasons why some patients are not suitable for discharge following day surgery. Method A pragmatic, mixed-methods approach was used to undertake a critical evaluation of the literature and current practice to determine what is already known about discharge following day surgery. Thematic analysis was used to identify the main themes and issues, enabling recommendations to be made to reduce the incidence of patients unable to be discharged following day surgery...
November 9, 2016: Nursing Standard
https://www.readbyqxmd.com/read/27845489/leishmaniasis-and-ifn-%C3%AE-dependent-chemokines
#11
P Fallahi, G Elia, A Bonatti
Leishmaniasis is a disease caused by Leishmania and spread by the bite of certain types of sandflies. Leishmaniasis affects as many as 12 million people worldwide, with 2 million new cases each year. Leishmania infection, and Leishmaniasis, following occupational exposure has been also reported. Three forms of Leishmaniasis are known: a- Cutaneous Leishmaniasis (CL); b-Mucocutaneous Leishmaniasis; c- Visceral Leishmaniasis (VL). The visceral form of Leishmaniasis has an estimated incidence of 500,000 new cases...
September 2016: La Clinica Terapeutica
https://www.readbyqxmd.com/read/27836002/cardiac-dysfunction-induced-by-weaning-from-mechanical-ventilation-incidence-risk-factors-and-effects-of-fluid-removal
#12
Jinglun Liu, Feng Shen, Jean-Louis Teboul, Nadia Anguel, Alexandra Beurton, Nadia Bezaz, Christian Richard, Xavier Monnet
BACKGROUND: Weaning-induced pulmonary oedema (WiPO) is a well-recognised cause of failure of weaning from mechanical ventilation, but its incidence and risk factors have not been reliably described. We wanted to determine the incidence and risk factors in a population of critically ill patients. In addition, we wanted to describe the effects of diuretics when they are administered in this context. METHODS: We monitored 283 consecutive spontaneous breathing trials (SBT; T-piece trial) performed in 81 patients...
November 12, 2016: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/27833664/factors-that-could-explain-the-increasing-prevalence-of-type-2-diabetes-among-adults-in-a-canadian-province-a-critical-review-and-analysis
#13
REVIEW
Véronique Thibault, Mathieu Bélanger, Emilie LeBlanc, Lise Babin, Stuart Halpine, Beverly Greene, Michelina Mancuso
BACKGROUND: The prevalence of diabetes has increased since the last decade in New Brunswick. Identifying factors contributing to the increase in diabetes prevalence will help inform an action plan to manage the condition. The objective was to describe factors that could explain the increasing prevalence of type 2 diabetes in New Brunswick since 2001. METHODS: A critical literature review was conducted to identify factors potentially responsible for an increase in prevalence of diabetes...
2016: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/27825363/pre-hospital-management-of-mass-casualty-civilian-shootings-a-systematic-literature-review
#14
Conor D A Turner, David J Lockey, Marius Rehn
BACKGROUND: Mass casualty civilian shootings present an uncommon but recurring challenge to emergency services around the world and produce unique management demands. On the background of a rising threat of transnational terrorism worldwide, emergency response strategies are of critical importance. This study aims to systematically identify, describe and appraise the quality of indexed and non-indexed literature on the pre-hospital management of modern civilian mass shootings to guide future practice...
November 8, 2016: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/27821184/a-core-outcome-set-for-neonatal-abstinence-syndrome-study-protocol-for-a-systematic-review-parent-interviews-and-a-delphi-survey
#15
Lauren E Kelly, Lauren M Jansson, Wendy Moulsdale, Jodi Pereira, Sarah Simpson, Astrid Guttman, Karel Allegaert, Lisa Askie, Henry Roukema, Thierry Lacaze, Jonathan M Davis, Loretta Finnegan, Paula Williamson, Martin Offringa
BACKGROUND: The prevalence of neonatal abstinence syndrome (NAS) is increasing globally resulting in an increased incidence of adverse neonatal outcomes and health system costs. Evidence regarding the effectiveness of NAS prevention and management strategies is very weak and further research initiatives are critically needed to support meta-analysis and clinical practice guidelines. In NAS research, the choice of outcomes and the use of valid, responsive and feasible measurement instruments are crucial...
November 8, 2016: Trials
https://www.readbyqxmd.com/read/27816160/amniotic-fluid-embolism
#16
REVIEW
Amir A Shamshirsaz, Steven L Clark
Amniotic fluid embolism remains one of the most devastating conditions in obstetric practice with an incidence of approximately 1 in 40,000 deliveries and a reported mortality rate ranging from 20% to 60%. The pathophysiology involves an abnormal maternal response to fetal tissue exposure associated with breaches of the maternal-fetal physiologic barrier during parturition. This response and its subsequent injury involve activation of proinflammatory mediators similar to that seen with the classic systemic inflammatory response syndrome...
December 2016: Obstetrics and Gynecology Clinics of North America
https://www.readbyqxmd.com/read/27812151/asymmetric-and-symmetric-dimethylarginine-as-risk-markers-for-total-mortality-and-cardiovascular-outcomes-a-systematic-review-and-meta-analysis-of-prospective-studies
#17
Sabrina Schlesinger, Svenja R Sonntag, Wolfgang Lieb, Renke Maas
BACKGROUND: A growing number of studies linked elevated concentrations of circulating asymmetric (ADMA) and symmetric (SDMA) dimethylarginine to mortality and cardiovascular disease (CVD) events. To summarize the evidence, we conducted a systematic review and quantified associations of ADMA and SDMA with the risks of all-cause mortality and incident CVD in meta-analyses accounting for different populations and methodological approaches of the studies. METHODS: Relevant studies were identified in PubMed until February 2015...
2016: PloS One
https://www.readbyqxmd.com/read/27811314/epigenetic-treatment-of-pancreatic-cancer-is-there-a-therapeutic-perspective-on-the-horizon
#18
REVIEW
Elisabeth Hessmann, Steven A Johnsen, Jens T Siveke, Volker Ellenrieder
Pancreatic ductal adenocarcinoma (PDAC) constitutes one of the most aggressive malignancies with a 5-year survival rate of <7%. Due to growing incidence, late diagnosis and insufficient treatment options, PDAC is predicted to soon become one of the leading causes of cancer-related death. Although intensified cytostatic combinations, particularly gemcitabine plus nab-paclitaxel and the folinic acid, fluorouracil, irinotecan, oxaliplatin (FOLFIRINOX) protocol, provide some improvement in efficacy and survival compared with gemcitabine alone, a breakthrough in the treatment of metastatic pancreatic cancer remains out of sight...
November 3, 2016: Gut
https://www.readbyqxmd.com/read/27803312/effect-of-tetrastarch-hydroxyethyl-starch-130-0-4-on-plasma-creatinine-concentration-in-cats-a-retrospective-analysis-2010-2015
#19
Ivayla D Yozova, Judith Howard, Katja N Adamik
OBJECTIVES: The objective was to determine survival and changes in creatinine concentrations after administration of 6% tetrastarch (hydroxyethyl starch [HES] 130/0.4) vs crystalloids in critically ill cats. METHODS: The medical records were reviewed for cats admitted to the intensive care unit with at least two plasma creatinine measurements and initial concentrations not exceeding the upper reference interval. Cats were excluded if they had received HES prior to admission or if they had received fluid therapy for <24 h between initial and subsequent measurements...
November 1, 2016: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/27797086/risk-factors-for-new-onset-delirium-in-patients-with-bloodstream-infections-independent-and-quantitative-effect-of-catheters-and-drainages-a-four-year-cohort-study
#20
Tolga Dittrich, Sarah Tschudin-Sutter, Andreas F Widmer, Stephan Rüegg, Stephan Marsch, Raoul Sutter
BACKGROUND: Bloodstream infections (BSI) and delirium are frequent in critically ill patients. During systemic inflammatory response to BSI, cytokines may interact with neurotransmitters and neuronal receptors driving acute brain dysfunction. However, prospectively collected data on incidence, prediction and impact of delirium in association with BSI are lacking. This study aimed to determine the incidence and predictors of new-onset delirium and its impact on outcome in critically ill adult patients with BSI...
December 2016: Annals of Intensive Care
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