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https://www.readbyqxmd.com/read/28648039/-effects-of-combined-application-of-culture-supernatant-of-human-umbilical-cord-mesenchymal-stem-cells-and-ciprofloxacin-on-staphylococcus-aureus-in-vitro
#1
B Zhou, H L Tu, T Ba, L F Wang, S J Wang, S Y Nie
Objective: To explore the effects of combined application of culture supernatant of human umbilical cord mesenchymal stem cells (hUCMSCs) and ciprofloxacin on Staphylococcus aureus (SA) in vitro. Methods: hUCMSCs were isolated from umbilical cord tissue of full-term healthy fetus after cesarean section and cultured. Cells in the third passage were used in the experiments after identification. SA strains isolated from wounds of burn patients in our burn wards were used in the experiments. Cells were divided into 0, 10, 100, and 1 000 ng/mL lipopolysaccharide (LPS) groups according to the random number table (the same dividing method below)...
June 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28648005/-components-of-human-placental-extract-and-its-protective-effect-to-rat-from-d-galn-induced-acute-liver-injury
#2
H Q Lei, M L Cheng, J Li, P P Zhou, X H Luo, F Yu
Objective: To evaluate the effect of human placental extracts (HPE) on the protection from acute liver injury (ALI) induced by D-GalN and analyze the components of HPE. Methods: (1)Fourty male mice were randomly divided into five groups (Blank, Model, MgIG, HPE and HPE+ MgIG) for the ALI model and treatments.The serum alanine aminotransferase (ALT) and aspartate transaminase (AST) were determined by biochemical assays.Nitric monoxide (NO), malondialdehyde (MDA), superoxide dismutase (SOD), total antioxidant capacity (T-AOC) in serum and hepatic tissue were detected by assay kits...
June 20, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28647986/-studies-on-the-serum-types-and-identification-efficiency-on-diarrheagenic-escherichia-coli-isolated-from-diarrhea-patients-in-zhejiang-province
#3
F Yu, R N Wang, X Chen, S F Zheng, Y Y Wang, Y Chen
Objective: To investigate the serotypes of Diarrheagenic Escherichia coli (DEC) isolated from diarrheal patients in Zhejiang province and to explore the identification efficiency of serological screening methods. Methods: Serological agglutination tests were carried out in 696 strains of DEC (through the identification of virulence genes) which were selected from the Infectious Diarrhea Pathogen Monitoring Network Strain Bank of Zhejiang province, from July 2009 to June 2013. Results of virulence genes, serological identification and classification were compared...
June 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28647952/children-with-short-stature-and-growth-failure-heightism-gender-and-racial-disparities
#4
Terri H Lipman, Ian J McCurry
Growth is the single most important indication of the health of a child. Identification of growth disorders in all children is crucial as growth failure can be the first sign of a number of acute and chronic conditions. However, gender and racial biases have resulted in inequities in the identification, referral and treatment of children with growth disorders. In addition, short children have been impacted by a number of psychosocial issues. Heightism is prejudice or discrimination against individuals based on height, and refers to discrimination against individuals whose height is not within the normal acceptable range...
June 2017: Pediatric Endocrinology Reviews: PER
https://www.readbyqxmd.com/read/28647950/turner-syndrome-care-of-the-patient-birth-to-late-adolescence
#5
Denise Gruccio Paolucci, Vaneeta Bamba
Turner syndrome (TS) is a genetic condition occurring in females resulting from the loss of part or all of one of the X chromosomes. The two hallmark features of Turner syndrome include short stature and primary ovarian insufficiency. In addition, Turner syndrome can involve multiple healthcare issues including cardiac and renal anomalies, autoimmune disorders, hearing loss, ophthalmologic issues, bone anomalies, dermatologic issues and psychosocial and educational concerns. The presenting signs of Turner syndrome can vary markedly, leading to delayed or even missed diagnosis...
June 2017: Pediatric Endocrinology Reviews: PER
https://www.readbyqxmd.com/read/28647933/a-new-system-of-documentation-to-improve-dietitian-physician-crosstalk
#6
Shelly Rachman-Elbaum, Aliza H Stark, Josefa Kachal, Teresa W Johnson, Bat Sheva Porat-Katz
BACKGROUND: Standardization of the dietetic care process allows for early identification of malnutrition and metabolic disorders, interdisciplinary collaboration among the medical team, and improved quality of patient care. Globally, dietitians are adopting a nutrition care model that integrates national regulations with professional scope of practice. Currently, Israel lacks a standardized dietetic care process and documentation terminology. OBJECTIVES: To assess the utilization of a novel sectoral documentation system for nutrition care in Israel...
June 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/28647924/comparative-expression-analysis-of-rice-and-arabidopsis-peroxiredoxin-genes-suggests-conserved-or-diversified-roles-between-the-two-species-and-leads-to-the-identification-of-tandemly-duplicated-rice-peroxiredoxin-genes-differentially-expressed-in-seeds
#7
Yun-Shil Gho, Sun-A Park, Sung-Ruyl Kim, Anil Kumar Nalini Chandran, Gynheung An, Ki-Hong Jung
BACKGROUND: Peroxiredoxins (PRXs) have recently been identified as plant antioxidants. Completion of various genome sequencing projects has provided genome-wide information about PRX genes in major plant species. Two of these -- Oryza sativa (rice) and Arabidopsis -- each have 10 PRX members. Although significant progress has been made in understanding their biological roles in Arabidopsis, those functions in rice, a model crop plant, have not been well studied. RESULTS: We performed a comparative expression analysis of rice and Arabidopsis PRXs...
December 2017: Rice
https://www.readbyqxmd.com/read/28647923/foodborne-illness-outbreak-investigation-in-a-high-profile-sports-club
#8
Kwendy Cavanagh, Travers Johnstone, Essi Huhtinen, Zeina Najjar, Peter Lorentzos, Craig Shadbolt, John Shields, Leena Gupta
A foodborne illness outbreak involving an elite sports team was investigated by a public health unit in Sydney, Australia. An epidemiological association was established between gastrointestinal illness and the consumption of food supplied by an external caterer, with a lamb meal most strongly associated with illness. Genetically identical Salmonella isolates were identified from clinical specimens, residual food items, and an environmental swab taken from the catering premises. The training schedule and other club operations were significantly affected by this outbreak...
December 2017: Sports Medicine—Open
https://www.readbyqxmd.com/read/28647921/proteome-profile-of-aspergillus-terreus-conidia-at-germinating-stage-identification-of-probable-virulent-factors-and-enzymes-from-mycotoxin-pathways
#9
Raman Thakur, Jata Shankar
Aspergillus terreus is an emerging opportunistic fungal pathogen that causes invasive aspergillosis in immunocompromised individuals. The main risk group of individuals for this organism is leukopenic patients, individuals having cancers, bone marrow transplant persons and those who have immunological disorders. The lack of early diagnostic marker for A. terreus and intrinsic resistance to Amphotericin B, further limits the successful therapy of A. terreus-associated infections. The germination of inhaled conidia is the key step to establish successful invasion in host tissues or organs...
June 24, 2017: Mycopathologia
https://www.readbyqxmd.com/read/28647912/chemiluminescent-immunoassay-technology-what-does-it-change-in-autoantibody-detection
#10
Luigi Cinquanta, Desré Ethel Fontana, Nicola Bizzaro
Diagnostic technology is rapidly evolving, and over the last decade, substantial progress has been made even for the identification of antibodies, increasingly approaching this type of diagnostic to that of automated clinical chemistry laboratory. In this review, we describe the analytical and diagnostic characteristics of chemiluminescence technology in its strength and in its applicability for a more rapid and accurate diagnosis of autoimmune diseases. The wide dynamic range, greater than that of immunoenzymatic methods, the high sensitivity and specificity of the results expressed in quantitative form, the high degree of automation and the clinical implications related to the reduction in the turnaround time, and the ability to run a large number of antibody tests (even of different isotypes), directed towards large antigenic panels in random access mode, make this technology the most advanced in the clinical laboratory, with enormous repercussions on the workflow and on the autoimmunology laboratory organisation...
December 2017: Auto- Immunity Highlights
https://www.readbyqxmd.com/read/28647901/in-vivo-visualization-of-the-locus-coeruleus-in-humans-quantifying-the-test-retest-reliability
#11
Klodiana-Daphne Tona, Max C Keuken, Mischa de Rover, Egbert Lakke, Birte U Forstmann, Sander Nieuwenhuis, Matthias J P van Osch
The locus coeruleus (LC) is a brainstem nucleus involved in important cognitive functions. Recent developments in neuroimaging methods and scanning protocols have made it possible to visualize the human LC in vivo by utilizing a T1-weighted turbo spin echo (TSE) scan. Despite its frequent use and its application as a biomarker for tracking the progress of monoaminergic-related neurodegenerative diseases, no study to date has investigated the reproducibility and inter-observer variability of LC identification using this TSE scan sequence...
June 24, 2017: Brain Structure & Function
https://www.readbyqxmd.com/read/28647872/identification-and-characterization-of-intramolecular-%C3%AE-halo-interaction-in-d-0-complexes-a-theoretical-approach
#12
Tanay Debnath, Tamalika Ash, Subhendu Sarkar, Abhijit K Das
A mechanistic investigation to detect intramolecular M⋯X-C type interactions in d(0) neutral and cationic complexes was carried out through a benchmark study employing different density functional methods. As γ-halogen is involved in M⋯X-C type interactions, it is denoted as a γ-halo interaction and the respective conformers are designated as halo-conformers. By analyzing the geometrical parameters of halo-conformers, it was observed that, irrespective of the nature of the metal and the halogen, the Cγ-X bond distance increases compared to the usual C-X bond, which brings the M and X centers close enough to generate a weak interaction...
July 2017: Journal of Molecular Modeling
https://www.readbyqxmd.com/read/28647776/sentinel-node-biopsy-for-axillary-management-after-neoadjuvant-therapy-for-breast-cancer-a-single-center-retrospective-analysis-with-long-follow-up
#13
Yoshinari Ogawa, Katsumi Ikeda, Chika Watanabe, Yuri Kamei, Shinya Tokunaga, Yuko Tsuboguchi, Takeshi Inoue, Hiroko Fukushima, Makoto Ichiki
PURPOSE: Sentinel node biopsy (SNB) after neoadjuvant therapy (NAT) for breast cancer remains controversial. We conducted a retrospective study of patients who underwent SNB after NAT to evaluate the effectiveness of this procedure. METHODS: A consecutive 105 women with locally advanced breast cancer (cT1-4, cN0-3, M0) were treated with NAT between 2006 and 2015. The subjects were 80 of these patients who became or remained clinically node-negative after NAT, 53 of whom had axillary management determined by SNB (group A) and the other 27 underwent axillary lymph node dissection (ALND) without SNB (group B)...
June 24, 2017: Surgery Today
https://www.readbyqxmd.com/read/28647774/automatic-identification-of-coronary-tree-anatomy-in-coronary-computed-tomography-angiography
#14
Qing Cao, Alexander Broersen, Michiel A de Graaf, Pieter H Kitslaar, Guanyu Yang, Arthur J Scholte, Boudewijn P F Lelieveldt, Johan H C Reiber, Jouke Dijkstra
An automatic coronary artery tree labeling algorithm is described to identify the anatomical segments of the extracted centerlines from coronary computed tomography angiography (CCTA) images. This method will facilitate the automatic lesion reporting and risk stratification of cardiovascular disease. Three-dimensional (3D) models for both right dominant (RD) and left dominant (LD) coronary circulations were built. All labels in the model were matched with their possible candidates in the extracted tree to find the optimal labeling result...
June 24, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28647766/impact-of-patient-questionnaires-on-completeness-of-clinical-information-and-identification-of-causes-of-pain-during-outpatient-abdominopelvic-ct-interpretation
#15
Ankur M Doshi, Chenchan Huang, Luke Ginocchio, Krishna Shanbhogue, Andrew B Rosenkrantz
PURPOSE: To evaluate the impact of questionnaires completed by patients at the time of abdominopelvic CT performed for abdominal pain on the completeness of clinical information and the identification of potential causes of pain, compared with order requisitions alone. METHODS: 100 outpatient CT examinations performed for the evaluation of abdominal pain were retrospectively reviewed. The specificity of the location of pain was compared between the order requisition and patient questionnaire...
June 24, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28647758/a-meta-analysis-of-quantitative-trait-loci-for-abiotic-and-biotic-stress-resistance-in-tetraploid-cotton
#16
Abdelraheem Abdelraheem, Feng Liu, Mingzhou Song, Jinfa F Zhang
The number and location of mapped quantitative trait loci (QTL) depend on genetic populations and testing environments. The identification of consistent QTL across genetic backgrounds and environments is a pre-requisite to marker-assisted selection. This study analyzed a total of 661 abiotic and biotic stress resistance QTL based on our previous work and other publications using the meta-analysis software Biomercator. It identified chromosomal regions containing QTL clusters for different resistance traits and hotspots for a particular resistance trait in cotton from 98 QTL for drought tolerance under greenhouse (DT) and 150 QTL in field conditions (FDT), 80 QTL for salt tolerance in the greenhouse conditions (ST), 201 QTL for resistance to Verticillium wilt (VW, Verticillium dahliae), 47 QTL for resistance to Fusarium wilt (FW, Fusarium oxysporum f...
June 24, 2017: Molecular Genetics and Genomics: MGG
https://www.readbyqxmd.com/read/28647684/dynamics-of-helicobacter-pylori-infection-as-a-determinant-of-progression-of-gastric-precancerous-lesions-16-year-follow-up-of-an-eradication-trial
#17
Robertino M Mera, Luis E Bravo, M Constanza Camargo, Juan C Bravo, Alberto G Delgado, Judith Romero-Gallo, Maria C Yepez, José L Realpe, Barbara G Schneider, Douglas R Morgan, Richard M Peek, Pelayo Correa, Keith T Wilson, M Blanca Piazuelo
OBJECTIVE: To evaluate the long-term effect of cumulative time exposed to Helicobacter pylori infection on the progression of gastric lesions. DESIGN: 795 adults with precancerous gastric lesions were randomised to receive anti-H. pylori treatment at baseline. Gastric biopsies were obtained at baseline and at 3, 6, 12 and 16 years. A total of 456 individuals attended the 16-year visit. Cumulative time of H. pylori exposure was calculated as the number of years infected during follow-up...
June 24, 2017: Gut
https://www.readbyqxmd.com/read/28647652/kinase-activity-in-recurring-primary-skull-base-chordomas-and-chondrosarcomas-identification-of-novel-pathways-of-oncogenesis-and-potential-drug-targets
#18
Philip Tatman, Joshua Osbun, Youssef Yakkioui, Sumanpret Kaur, Carolina Parada, Tina Busald, Donald Born, Owais Ahmad, Jing Zhang, Manuel Ferreira
OBJECTIVE: Chordomas and chondrosarcomas are tumors that can occur in the skull base. Currently, 45% of chordomas and 56% of chondrosarcomas recur within five years of surgery. The role of adjuvant therapy is highly debated. No pharmacotherapies have been approved by the FDA for chordomas or chondrosarcomas. The high propensity for recurrence and lack of definitive adjuvant therapy necessitates additional basic science research to identify molecular anomalies associated with recurrent disease...
June 21, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28647647/itraq-based-quantitative-analysis-of-alveolar-bone-resorption-in-rats-with-experimental-periodontitis
#19
Weidong Yang, Yafan Gao, Yajie Qian, Jingjing Li, Qingang Hu
OBJECTIVE: Periapical periodontitis results in alveolar bone resorption around the root apex. During the progression of inflammation, host cells release various inflammatory mediators and pro-inflammatory cytokines through immune responses. However, the pathological mechanisms associated with periapical bone destruction remain unclear. This study was objected to identify differentially regulated proteins in periapical periodontitis via a quantitative proteomics approach using isobaric tags for relative and absolute quantification (iTRAQ) labelling of peptides...
June 13, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28647587/sampling-frequency-for-water-quality-variables-in-streams-systems-analysis-to-quantify-minimum-monitoring-rates
#20
Nick A Chappell, Timothy D Jones, Wlodek Tych
Insufficient temporal monitoring of water quality in streams or engineered drains alters the apparent shape of storm chemographs, resulting in shifted model parameterisations and changed interpretations of solute sources that have produced episodes of poor water quality. This so-called 'aliasing' phenomenon is poorly recognised in water research. Using advances in in-situ sensor technology it is now possible to monitor sufficiently frequently to avoid the onset of aliasing. A systems modelling procedure is presented allowing objective identification of sampling rates needed to avoid aliasing within strongly rainfall-driven chemical dynamics...
June 19, 2017: Water Research
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