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Oxytocin; obstetric

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https://www.readbyqxmd.com/read/27904165/a-retrospective-perinatal-data-analysis-of-immigrant-and-german-women-from-representative-birth-cohorts-at-the-virchow-hospital-berlin
#1
R Armbrust, R von Rennenberg, M David
Introduction: The aim of this study was to define and characterise differences in the level of obstetric care provided to immigrant and German women. Materials and Methods: An analysis of the Virchow Hospital's birth registers was conducted for the years 1974, 1984 and 1994. The study population of 5445 patients was grouped according to ancestry/family origin on the basis of a name analysis, and subsequently also according to parity (primiparous or multiparous). On name analysis 2741 women were defined as German, 1598 were grouped as women of Turkish origin and 810 as immigrants of other origin...
November 2016: Geburtshilfe und Frauenheilkunde
https://www.readbyqxmd.com/read/27862855/effect-of-oxytocin-infusion-on-reducing-the-blood-loss-during-abdominal-myomectomy-a-double-blind-randomised-controlled-trial
#2
S Atashkhoei, S Fakhari, H Pourfathi, E Bilehjani, P M Garabaghi, A Asiaei
OBJECTIVE: To assess the effectiveness and safety of oxytocin to reduce blood loss during abdominal myomectomy. DESIGN: Double-blind randomised controlled trial. SETTING: Obstetrics and Gynecologic University Medical Centre. POPULATION: Eighty healthy women candidates for abdominal myomectomy. METHODS: Women were randomly assigned to two groups. In the study group (n = 40) oxytocin 30 IU in 500 ml normal saline; and in the placebo group (n = 40) pure normal saline was administered during myomectomy...
November 15, 2016: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27855051/-carbetocin-and-oxytocin-prevention-of-postpartum-hemorrhage-in-patients-with-risk-factors-for-uterine-atony
#3
Santiago Carrillo-Gaucín, Luis Guillermo Torres-Gómez
BACKGROUND: In Mexico, during 2010, obstetric hemorrhage was second (19.6%) as a direct cause of maternal death. The aim of this paper is to evaluate the effect of oxytocin and carbetocin, in preventing postpartum hemorrhage in patients with risk factors for uterine atony. METHODS: Study type clinical trial, patients experiencing at least one of the risk factors for uterine atony included. Randomly, they were divided into two groups: one was given Oxytocin and other received Carbetocin...
2016: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/27833251/cross-sectional-study-on-the-obstetric-performance-of-primigravidae-in-a-teaching-hospital-in-lagos-nigeria
#4
Kehinde Sharafadeen Okunade, Halimat Okunola, Lawal Oyeneyin, Fatimah N Habeeb-Adeyemi
BACKGROUND: A woman carrying her first pregnancy is starting a new life, and this is a crucial time in her obstetric career. This study was aimed to compare the obstetric performance of primigravidae to that of the multigravidae with a view to suggesting ways of preventing the associated complications. PATIENTS AND METHODS: The study was a cross-sectional case-control study carried out among women who delivered in the study center over a year period. Relevant data of primigravid parturients who delivered in the hospital were retrieved from the labor ward register, and an equal number of multigravidae who delivered during the same study were selected by simple random sampling as the control group...
September 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27832753/stillbirths-and-quality-of-care-during-labour-at-the-low-resource-referral-hospital-of-zanzibar-a-case-control-study
#5
Nanna Maaløe, Natasha Housseine, Ib Christian Bygbjerg, Tarek Meguid, Rashid Saleh Khamis, Ali Gharib Mohamed, Birgitte Bruun Nielsen, Jos van Roosmalen
BACKGROUND: To study determinants of stillbirths as indicators of quality of care during labour in an East African low resource referral hospital. METHODS: A criterion-based unmatched unblinded case-control study of singleton stillbirths with birthweight ≥2000 g (n = 139), compared to controls with birthweight ≥2000 g and Apgar score ≥7 (n = 249). RESULTS: The overall facility-based stillbirth rate was 59 per 1000 total births, of which 25 % was not reported in the hospital's registers...
November 10, 2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27831958/anesthetic-and-obstetrical-factors-associated-with-the-effectiveness-of-epidural-analgesia-for-labor-pain-relief-an-observational-population-based-study
#6
Marie-Pierre Bonnet, Caroline Prunet, Christophe Baillard, Laure Kpéa, Béatrice Blondel, Camille Le Ray
BACKGROUND AND OBJECTIVES: The effectiveness of labor epidural analgesia is difficult to explore, as it includes the maternal satisfaction with analgesia as well as the overall childbirth experience. In this population-based study, we sought to identify factors associated with the effectiveness of epidural analgesia for labor pain relief. METHODS: We performed a secondary analysis of the 2010 French National Perinatal Survey, a cross-sectional study of a representative sample of births in France...
November 9, 2016: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/27793112/effect-of-planned-place-of-birth-on-obstetric-interventions-and-maternal-outcomes-among-low-risk-women-a-cohort-study-in-the-netherlands
#7
N Bolten, A de Jonge, E Zwagerman, P Zwagerman, T Klomp, J J Zwart, C C Geerts
BACKGROUND: The use of interventions in childbirth has increased the past decades. There is concern that some women might receive more interventions than they really need. For low-risk women, midwife-led birth settings may be of importance as a counterbalance towards the increasing rate of interventions. The effect of planned place of birth on interventions in the Netherlands is not yet clear. This study aims to give insight into differences in obstetric interventions and maternal outcomes for planned home versus planned hospital birth among women in midwife-led care...
October 28, 2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27769193/maternal-near-miss-and-quality-of-care-in-a-rural-rwandan-hospital
#8
Richard Kalisa, Stephen Rulisa, Thomas van den Akker, Jos van Roosmalen
BACKGROUND: The WHO Maternal Near Miss (MNM) approach was developed to evaluate and improve quality of obstetric care worldwide. This study aimed to study the incidence of MNM and quality of care at a district hospital in rural Rwanda by applying this approach. METHODS: A facility based, prospective cohort study conducted at a district hospital in rural Rwanda between June 2013 and December 2014. Subjects were followed from time of admission to discharge or death...
October 21, 2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27726928/-risk-of-uterine-rupture-in-vaginal-birth-after-cesarean-systematic-review
#9
Pedro Hidalgo-Lopezosa, María Hidalgo-Maestre
OBJECTIVE: To assess the risk of uterine rupture (UR) in attempted vaginal birth after cesarean and to identify risk factors. METHODS: Systematic review by consulting the following databases: PubMed (MEDLINE), Cochrane Library Plus, Embase, Nursing@Ovid, Cuidatge and Dialnet. The search was conducted between January and March 2015. MeSH descriptors used were: vaginal birth after cesarean; uterine rupture; labor induced and labor obstetric or trial of labor. There were no restrictions on date or language...
October 7, 2016: Enfermería Clínica
https://www.readbyqxmd.com/read/27725717/uterus-targeted-liposomes-for-preterm-labor-management-studies-in-pregnant-mice
#10
Jerrie S Refuerzo, Fransisca Leonard, Nataliya Bulayeva, David Gorenstein, Giuseppe Chiossi, Alejandra Ontiveros, Monica Longo, Biana Godin
Preterm labor caused by uterine contractions is a major contributor to neonatal morbidity and mortality. Treatment intended to reduce uterine contractions include tocolytic agents, such as indomethacin. Unfortunately, clinically used tocolytics are frequently inefficient and cross the placenta causing fetal side effects. Here we show for the first time in obstetrics the use of a targeted nanoparticle directed to the pregnant uterus and loaded with a tocolytic for reducing its placental passage and sustaining its efficacy...
October 11, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27692473/effect-of-combined-spinal-epidural-analgesia-in-labor-on-frequency-of-emergency-cesarean-delivery-among-nulliparous-chinese-women
#11
Fen Wang, Yun-Xia Cao, Shan-Gao Ke, Tao-Hua Zhu, Miao Zhang
OBJECTIVE: To determine whether combined spinal-epidural analgesia (CSEA) during labor increases the frequency of emergency cesarean delivery among Chinese nulliparous women. METHODS: In a retrospective study, the medical records of nulliparous women with a singleton fetus in cephalic presentation who delivered at term at Tongling Maternity Hospital, China, between January 2012 and December 2014 were reviewed. Information about CSEA, mode of delivery, labor duration, oxytocin augmentation, and neonatal outcome was obtained...
December 2016: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/27661990/the-effect-of-labor-on-the-intraocular-pressure-in-healthy-women
#12
Amit Meshi, Sharon Armarnik, Michael Mimouni, Fani Segev, Ori Segal, Hagai Kaneti, Ehud I Assia, Noa Geffen
PURPOSE: To investigate the effect of modern vaginal labor using epidural anesthesia on the intraocular pressure (IOP) and on the mean ocular perfusion pressure (MOPP) in healthy women. PATIENTS AND METHODS: In this prospective observational study, eligible candidates were healthy pregnant women for vaginal delivery with epidural anesthesia, with a singleton pregnancy, who were admitted to the delivery room in the first phase of the first stage of labor. Demographic data as well as medical and obstetric history were obtained at baseline, followed by performance of a biomicroscopic examination...
September 21, 2016: Journal of Glaucoma
https://www.readbyqxmd.com/read/27651612/role-of-tranexamic-acid-in-reducing-blood-loss-in-vaginal-delivery
#13
Priyankur Roy, M S Sujatha, Ambarisha Bhandiwad, Bivas Biswas
INTRODUCTION: Anti-fibrinolytic agents are used to reduce obstetric blood loss as the fibrinolytic system is known to get activated after placental delivery. OBJECTIVES: To evaluate the efficacy of parenteral tranexamic acid in reducing blood loss during normal labour and to compare it with the amount of blood loss in patients who received placebo in the third stage of labour. METHODOLOGY: Patients with spontaneous labour or planned for induction of labour and fulfilling the inclusion criteria were recruited for the study...
October 2016: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/27651577/unscarred-uterine-rupture-a-retrospective-analysis
#14
Manisha Vernekar, Roy Rajib
INTRODUCTION: Uterine rupture is a catastrophic obstetrical emergency associated with a significant feto-maternal morbidity and mortality. Many risk factors for uterine rupture, as well as a wide range of clinical presentations, have been identified. OBJECTIVES: To analyze the frequency, predisposing factors, and maternal and fetal outcomes of uterine rupture. METHODS: A retrospective analysis of cases of unscarred uterine rupture was conducted at the Department of Obstetrics and Gynecology, RIMS, Imphal from June 1, 2010 to June 30, 2012...
October 2016: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/27651574/a-retrospective-case-control-study-evaluating-the-role-of-mifepristone-for-induction-of-labor-in-women-with-previous-cesarean-section
#15
Chanderdeep Sharma, Anjali Soni, Pawan K Soni, Suresh Verma, Ashok Verma, Amit Gupta
OBJECTIVE: To investigate the role of "mifepristone" for induction of labor (IOL) in pregnant women with prior cesarean section (CS). METHODS: In this retrospective study, all pregnant women with prior CS who received oral mifepristone (400 mg) for IOL (as per clear obstetric indications) [group 1] were compared with pregnant women with prior CS who had spontaneous onset of labor (SOL) [group 2], with respect to incidence of vaginal delivery, CS, duration of labor, and various maternal and fetal outcomes...
October 2016: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/27567564/drug-delivery-to-the-human-and-mouse-uterus-using-immunoliposomes-targeted-to-the-oxytocin-receptor
#16
Jonathan W Paul, Susan Hua, Marina Ilicic, Jorge M Tolosa, Trent Butler, Sarah Robertson, Roger Smith
BACKGROUND: The ability to provide safe and effective pharmacotherapy during obstetric complications, such as preterm labor or postpartum hemorrhage, is hampered by the systemic toxicity of therapeutic agents leading to adverse side effects in the mother and fetus. Development of novel strategies to target tocolytic and uterotonic agents specifically to uterine myocytes would improve therapeutic efficacy while minimizing the risk of side effects. Ligand-targeted liposomes have emerged as a reliable and versatile platform for targeted drug delivery to specific cell types, tissues or organs...
August 24, 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27499647/combined-uterine-and-urinary-bladder-rupture-an-unusual-complication-of-obstructed-labor-in-a-primigravida
#17
Idris Usman Takai, Abdulkadir Abubakar
BACKGROUND: Combined uterine and urinary bladder rupture following prolonged obstructed labor is indeed a momentous uro-obstetric emergency. The urinary bladder involvement is distinctly rare in the absence of factors that predispose the bladder to be adherent to the lower uterine segment and is quite unusual in a primigravida. OBJECTIVE: To report a rare case of uterine rupture involving urinary bladder secondary to a prolonged obstructed labor in a primigravida from a low resource setting...
2016: International Journal of Women's Health
https://www.readbyqxmd.com/read/27476252/-active-management-of-the-third-stage-of-labor-three-schemes-of-oxytocin-randomised-clinical-trial
#18
RANDOMIZED CONTROLLED TRIAL
M Neri-Mejía, A G Pedraza-Avilés
OBJECTIVE: To compare the effectiveness of intramuscular oxytocin against intravenous oxytocin against intravenous traditional oxytocin infusion, in the active management of the third period of the delayed impingement labor work and controlled cord traction. METHODS: Randomized controlled blinded clinical trial. In women age 14 to 40 with full term pregnancy, childbirth attended by ISSSTE's Regional Hospital "Gral. Ignacio Zaragoza", in the period from August to December 2015...
May 2016: Ginecología y Obstetricia de México
https://www.readbyqxmd.com/read/27476027/midwifery-practice-and-maternity-services-a-multisite-descriptive-study-in-latin-america-and-the-caribbean
#19
Lorena Binfa, Loreto Pantoja, Jovita Ortiz, Gabriel Cavada, Peter Schindler, Rosa Ypania Burgos, Célia Regina Maganha E Melo, Lúcia Cristina Florentino Pereira da Silva, Marlise de Oliveira Pimentel Lima, Laura Valli Hernández, Rosana Schlenker Rm, Verdún Sánchez, Mirian Solis Rojas, Betty Cruz Huamán, Maria Luisa Torres Chauca, Alicia Cillo, Susana Lofeudo, Sandra Zapiola, Fiona Weeks, Jennifer Foster
OBJECTIVE: over the past three decades there has been a social movement in Latin American countries (LAC) to support humanised, physiologic birth. Rates of caesarean section overall in Latin America are approximately 35%, increasing up to 85% in some cases. There are many factors related to poor outcomes with regard to maternal and newborn/infant health in LAC countries. Maternal and perinatal outcome data within and between countries is scarce and inaccurate. The aims of this study were to: i) describe selected obstetric and neonatal outcomes of women who received midwifery care, ii) identify the level of maternal well-being after experiencing midwifery care in 6 Latin America countries...
September 2016: Midwifery
https://www.readbyqxmd.com/read/27469988/adverse-obstetric-outcomes-after-local-treatment-for-cervical-preinvasive-and-early-invasive-disease-according-to-cone-depth-systematic-review-and-meta-analysis
#20
Maria Kyrgiou, Antonios Athanasiou, Maria Paraskevaidi, Anita Mitra, Ilkka Kalliala, Pierre Martin-Hirsch, Marc Arbyn, Phillip Bennett, Evangelos Paraskevaidis
OBJECTIVE:  To assess the effect of treatment for cervical intraepithelial neoplasia (CIN) on obstetric outcomes and to correlate this with cone depth and comparison group used. DESIGN:  Systematic review and meta-analysis. DATA SOURCES:  CENTRAL, Medline, Embase from 1948 to April 2016 were searched for studies assessing obstetric outcomes in women with or without previous local cervical treatment. DATA EXTRACTION AND SYNTHESIS:  Independent reviewers extracted the data and performed quality assessment using the Newcastle-Ottawa criteria...
2016: BMJ: British Medical Journal
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