Anna Pedrinolla, Masoud Isanejad, Cinzia Antognelli, Desirée Bartolini, Consuelo Borras, Valentina Cavedon, Gabriele Di Sante, Anna Migni, Cristina Mas-Bargues, Chiara Milanese, Claudia Baschirotto, Roberto Modena, Alessandra Pistilli, Mario Rende, Federico Schena, Anna Maria Stabile, Nicola Vincenzo Telesa, Sara Tortorella, Kay Hemmings, Jose Vina, Eivind Wang, Anne McArdle, Malcolm J Jackson, Massimo Venturelli, Francesco Galli
OBJECTIVE: Protein-energy malnutrition and the subsequent muscle wasting (sarcopenia) are common ageing complications. It is knowing to be also associated with dementia. Our programme will test the cytoprotective functions of vitamin E combined with the cortisol-lowering effect of chocolate polyphenols (PP), in combination with muscle anabolic effect of adequate dietary protein intake and physical exercise to prevent the age-dependent decline of muscle mass and its key underpinning mechanisms including mitochondrial function, and nutrient metabolism in muscle in the elderly...
December 22, 2023: BMJ Open