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https://www.readbyqxmd.com/read/29222685/prediction-of-outcome-using-pretreatment-18f-fdg-pet-ct-and-mri-radiomics-in-locally-advanced-cervical-cancer-treated-with-chemoradiotherapy
#1
François Lucia, Dimitris Visvikis, Marie-Charlotte Desseroit, Omar Miranda, Jean-Pierre Malhaire, Philippe Robin, Olivier Pradier, Mathieu Hatt, Ulrike Schick
PURPOSE: The aim of this study is to determine if radiomics features from 18fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) and magnetic resonance imaging (MRI) images could contribute to prognoses in cervical cancer. METHODS: One hundred and two patients (69 for training and 33 for testing) with locally advanced cervical cancer (LACC) receiving chemoradiotherapy (CRT) from 08/2010 to 12/2016 were enrolled in this study. 18F-FDG PET/CT and MRI examination [T1, T2, T1C, diffusion-weighted imaging (DWI)] were performed for each patient before CRT...
December 9, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29220515/busco-applications-from-quality-assessments-to-gene-prediction-and-phylogenomics
#2
Robert M Waterhouse, Mathieu Seppey, Felipe A Simão, Mosè Manni, Panagiotis Ioannidis, Guennadi Klioutchnikov, Evgenia V Kriventseva, Evgeny M Zdobnov
Genomics promises comprehensive surveying of genomes and metagenomes, but rapidly changing technologies and expanding data volumes make evaluation of completeness a challenging task. Technical sequencing quality metrics can be complemented by quantifying completeness of genomic datasets in terms of the expected gene content of Benchmarking Universal Single-Copy Orthologs (BUSCO, http://busco.ezlab.org). The latest software release implements a complete refactoring of the code to make it more flexible and extendable to facilitate high-throughput assessments...
December 6, 2017: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/29217665/critical-determinants-of-combined-sprint-and-endurance-performance-an-integrative-analysis-from-muscle-fiber-to-the-human-body
#3
Stephan van der Zwaard, Willem J van der Laarse, Guido Weide, Frank W Bloemers, Mathijs J Hofmijster, Koen Levels, Dionne A Noordhof, Jos J de Koning, Cornelis J de Ruiter, Richard T Jaspers
Optimizing physical performance is a major goal in current physiology. However, basic understanding of combining high sprint and endurance performance is currently lacking. This study identifies critical determinants of combined sprint and endurance performance using multiple regression analyses of physiologic determinants at different biologic levels. Cyclists, including 6 international sprint, 8 team pursuit, and 14 road cyclists, completed a Wingate test and 15-km time trial to obtain sprint and endurance performance results, respectively...
December 7, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/29216446/comparison-of-two-equated-resistance-training-weekly-volume-routines-using-different-frequencies-on-body-composition-and-performance-in-trained-males
#4
Yue Fu, Bettina Karsten, Eneko Larumbe-Zabala, Marcos Seijo, Fernando Naclerio
The present study compared the effects of two weekly-equalized volume and relative load interventions on body composition, strength and power. Based on individual baseline maximal strength values, eighteen recreationally trained men were pair-matched and consequently randomly assigned to one of the following experimental groups: a low volume per session with a high frequency (LV-HF, n = 9) group who trained 4-days (Mondays, Tuesdays, Thursdays and Fridays) or a high volume per session and low frequency (HV-LF, n = 9) group who trained 2-days (Mondays and Thursdays)...
December 7, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29216285/myocardial-adaption-to-hi-r-t-in-previously-untrained-men-with-a-randomized-longitudinal-cardiac-mr-imaging-study-physical-adaptions-in-untrained-on-strength-and-heart-trial-push-trial
#5
Michael Scharf, Derya Oezdemir, Axel Schmid, Wolfgang Kemmler, Simon von Stengel, Matthias S May, Michael Uder, Michael M Lell
OBJECTIVE: Although musculoskeletal effects in resistance training are well described, little is known about structural and functional cardiac adaption in formerly untrained subjects. We prospectively evaluated whether short term high intensity (resistance) training (HI(R)T) induces detectable morphologic cardiac changes in previously untrained men in a randomized controlled magnetic resonance imaging (MRI) study. MATERIALS AND METHODS: 80 untrained middle-aged men were randomly assigned to a HI(R)T-group (n = 40; 43...
2017: PloS One
https://www.readbyqxmd.com/read/29214194/data-concerning-the-effect-of-plyometric-training-on-jump-performance-in-soccer-players-a-meta-analysis
#6
Maamer Slimani, Armin Paravlić, Nicola Luigi Bragazzi
Plyometric training (PT) enhances soccer performance, particularly vertical jump. However, the effectiveness of PT depends on various factors. A systematic search of the research literature was conducted for randomized controlled trials (RCTs) studying the effects of PT on countermovement jump (CMJ) height in soccer players. Ten studies were obtained through manual and electronic journal searches (up to April 2017). Significant differences were observed when compared: (1) PT group vs. control group (ES=0.85; 95% CI 0...
December 2017: Data in Brief
https://www.readbyqxmd.com/read/29212859/human-hair-follicle-transcriptome-profiling-a-minimally-invasive-tool-to-assess-molecular-adaptations-upon-low-volume-high-intensity-interval-training
#7
Jing Zhang, Sarah J Wallace, Maria Y Shiu, Ingrid Smith, Shawn G Rhind, Valerie S Langlois
High-intensity interval training (HIIT) has become a popular fitness training approach under both civilian and military settings. Consisting of brief and intense exercise intervals, HIIT requires less time commitment yet is able to produce the consistent targeted physical adaptations as conventional endurance training. To effectively characterize and monitor HIIT-induced cellular and molecular responses, a highly accessible yet comprehensive biomarker discovery source is desirable. Both gene differential expression (DE) and gene set (GS) analyses were conducted using hair follicle transcriptome established from pre and postexercise subjects upon a 10-day HIIT program by RNA-Seq, Comparing between pre and posttraining groups, differentially expressed protein coding genes were identified...
December 2017: Physiological Reports
https://www.readbyqxmd.com/read/29199186/neural-adaptations-after-short-term-wingate-based-high-intensity-interval-training
#8
A Vera-Ibañez, D Colomer-Poveda, S Romero-Arenas, M Viñuela-García, G Márquez
OBJECTIVES: This study examined the neural adaptations associated with a low-volume Wingate-based High Intensity Interval Training (HIIT). METHODS: Fourteen recreationally trained males were divided into an experimental (HIIT) and a control group to determine whether a short-term (4 weeks) Wingate-based HIIT program could alter the Hoffmann (H-) reflex, volitional (V-) wave and maximum voluntary contraction (MVC) of the plantar-flexor muscles, and the peak power achieved during a Wingate test...
December 1, 2017: Journal of Musculoskeletal & Neuronal Interactions
https://www.readbyqxmd.com/read/29198263/partnership-models-for-the-establishment-of-sustainable-paediatric-cardiac-surgical-and-cardiac-intensive-care-programmes-in-low-and-middle-income-countries
#9
Patricia Bastero, Sandra L Staveski, Bistra Zheleva, Emma Scanlan, Antonio G Cabrera, Aric Araujo, Guillermo Reyes, Carlos M Mery, Alexis Palacios-Macedo, Christian P Brizard
The care of patients with CHD remains a challenge in low- and middle-income countries. Their health systems have not been able to achieve consistently high performance in this field. The large volume of patients, manpower constraints, inconsistencies in the level and type of background training of the teams caring for this patient population, and the inadequate quality control systems are some of the barriers to achieving excellence of care. We describe three different international projects supporting the paediatric cardiac surgical and paediatric cardiac intensive care programmes in Latin America, Asia, and the Caribbean...
December 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/29196770/effect-of-gravity-acceleration-on-choroidal-and-retinal-nerve-fiber-layer-thickness-a-swept-source-optical-coherence-tomography-study
#10
Dong Yoon Kim, Jiho Song, Jin Young Kim, Kyungpil Choi, Sungmin Hyung, Ju Byung Chae
Purpose: The purpose of this study was to evaluate the effect of gravity acceleration on choroidal and retinal nerve fiber layer (RNFL) thickness using swept-source optical coherence tomography (SS-OCT). Methods: Thirteen healthy volunteers who planned to participate in human centrifuge training as part of the flight surgeon selection process enrolled this study. During centrifuge training, gravity was gradually increased up to six times that of sea level. All subjects underwent complete ophthalmologic examination and three-dimensional wide-scanning SS-OCT imaging (DRI OCT-1 Atlantis; Topcon, Tokyo, Japan)...
December 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29192644/automated-centrifugal-therapeutic-plasma-exchange-option-for-guillain-barre-syndrome-a-report-from-calabar-nigeria
#11
O E Iheanacho, C Chimeziem, B S Sachais, P A Shi
Therapeutic plasma exchange (TPE) is performed frequently and effectively in developed countries, whereas the reverse is the case in developing countries. Guillain-Barre syndrome (GBS), synonymous with acute inflammatory demyelinating polyneuropathy, is an important indication for TPE, but this is rarely administered in the treatment of such patients in Nigeria due to lack of such automated facility, limited expertise, and high cost. This report therefore presents an uncommon case of GBS in which automated TPE was utilized in the management, with the aims of highlighting the current status and challenges of therapeutic apheresis services in Nigeria...
October 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29192540/thoracoabdominal-breathing-motion-pattern-and-coordination-of-professional-ballet-dancers
#12
Isabella Martins Rodrigues, Gustavo Ramos Dalla Bernardina, Karine Jacon Sarro, Guido Baroni, Pietro Cerveri, Amanda Piaia Silvatti
Ballet training includes exercises of high and moderate intensities, which require breathing control for a good performance. This study describes the thoracoabdominal motion of professional dancers and compares the breathing patterns between professional dancers and non-dancers. Participants of this study were four male and four female (30.33 ± 4.64 years) professional dancers and four male and four female (22.75 ± 1.49 years) non-dancers. The participants executed two breathing manoeuvres while sitting motionless: quiet breathing (QB) and vital capacity (VC)...
December 1, 2017: Sports Biomechanics
https://www.readbyqxmd.com/read/29182403/long-distance-triathletes-intentions-to-manipulate-energy-and-macronutrient-intake-over-a-training-macrocycle
#13
Hani Kopetschny, David Rowlands, David Popovich, Jasmine Thomson
This study explored the information sources long-distance triathletes used to inform their training and nutrition plans, and evaluated these plans over a training macrocycle. Seventy-four long-distance triathletes completed the online survey. Coaches were the most popular training information source (69%), whereas non-professional sources (internet 65%, other athletes 53%) were more popular than nutritionists (29%) for nutrition information. Attributes valued most in an information source were: source prior personal experience, individualised advice, breadth of knowledge, and credibility...
November 28, 2017: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/29180829/automated-detection-of-geological-landforms-on-mars-using-convolutional-neural-networks
#14
Leon F Palafox, Christopher W Hamilton, Stephen P Scheidt, Alexander M Alvarez
The large volume of high-resolution images acquired by the Mars Reconnaissance Orbiter has opened a new frontier for developing automated approaches to detecting landforms on the surface of Mars. However, most landform classifiers focus on crater detection, which represents only one of many geological landforms of scientific interest. In this work, we use Convolutional Neural Networks (ConvNets) to detect both volcanic rootless cones and transverse aeolian ridges. Our system, named MarsNet, consists of five networks, each of which is trained to detect landforms of different sizes...
April 2017: Computers & Geosciences
https://www.readbyqxmd.com/read/29173080/eating-disorder-mental-health-literacy-what-do-psychologists-naturopaths-and-fitness-instructors-know
#15
Kate A Worsfold, Jeanie K Sheffield
At present, there are no known studies investigating the eating disorder mental health literacy (ED-MHL) of common frontline health providers such as psychologists, naturopaths, and fitness instructors. Little research also exists around practitioner knowledge for the spectrum of eating disorders. The current study sought to fill these research gaps and comprised 115 health practitioners who completed an online survey. A fictional vignette describing a female (Sarah) experiencing a subthreshold bulimic variant without purging was presented alongside common ED-MHL items...
November 27, 2017: Eating Disorders
https://www.readbyqxmd.com/read/29171108/optimization-and-validation-of-automated-hippocampal-subfield-segmentation-across-the-lifespan
#16
Andrew R Bender, Attila Keresztes, Nils C Bodammer, Yee Lee Shing, Markus Werkle-Bergner, Ana M Daugherty, Qijing Yu, Simone Kühn, Ulman Lindenberger, Naftali Raz
Automated segmentation of hippocampal (HC) subfields from magnetic resonance imaging (MRI) is gaining popularity, but automated procedures that afford high speed and reproducibility have yet to be extensively validated against the standard, manual morphometry. We evaluated the concurrent validity of an automated method for hippocampal subfields segmentation (automated segmentation of hippocampal subfields, ASHS; Yushkevich et al., ) using a customized atlas of the HC body, with manual morphometry as a standard...
November 23, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/29170706/the-effects-of-resistance-training-volume-on-skeletal-muscle-proteome
#17
Ramires A Tibana, Octávio L Franco, Gabriel V Cunha, Nuno M F Sousa, Ivo V Sousa Neto, Márcia M Carvalho, Jesser A Almeida, João L Q Durigan, Rita C Marqueti, James W Navalta, Mariana O Lobo, Fabricio A Voltarelli, Jonato Prestes
Studies are conflicting to whether low volume resistance training (RT) is as effective as high-volume RT protocols with respect to promoting morphological and molecular adaptations. Thus, the aim of the present study was to compare, using a climbing a vertical ladder, the effects of 8 weeks, 3 times per week, resistance training with 4 sets (RT4), resistance training with 8 sets (RT8) and without resistance training control (CON) on gastrocnemius muscle proteome using liquid chromatography mass spectrometry (LC-MS/MS) and cross sectional area (CSA) of rats...
2017: International Journal of Exercise Science
https://www.readbyqxmd.com/read/29168733/single-shot-detection-of-neurotransmitters-in-whole-blood-samples-by-means-of-the-heat-transfer-method-in-combination-with-synthetic-receptors
#18
Thijs Vandenryt, Bart van Grinsven, Kasper Eersels, Peter Cornelis, Safira Kholwadia, Thomas J Cleij, Ronald Thoelen, Ward De Ceuninck, Marloes Peeters, Patrick Wagner
Serotonin is an important neurotransmitter that plays a major role in the pathogenesis of a variety of conditions, including psychiatric disorders. The detection of serotonin typically relies on high-performance liquid chromatography (HPLC), an expensive technique that requires sophisticated equipment and trained personnel, and is not suitable for point-of-care applications. In this contribution, we introduce a novel sensor platform that can measure spiked neurotransmitter concentrations in whole blood samples in a fast and low-cost manner by combining synthetic receptors with a thermal readout technique-the heat-transfer method...
November 23, 2017: Sensors
https://www.readbyqxmd.com/read/29167386/ischemic-stroke-profile-risk-factors-and-outcomes-in-india-the-indo-us-collaborative-stroke-project
#19
P N Sylaja, Jeyaraj Durai Pandian, Subhash Kaul, M V Padma Srivastava, Dheeraj Khurana, Lee H Schwamm, Praveen Kesav, Deepti Arora, Aman Pannu, Tijy K Thankachan, Aneesh B Singhal
BACKGROUND AND PURPOSE: The Indo-US Collaborative Stroke Project was designed to characterize ischemic stroke across 5 high-volume academic tertiary hospitals in India. METHODS: From January 2012 to August 2014, research coordinators and physician coinvestigators prospectively collected data on 2066 patients with ischemic stroke admitted <2 weeks after onset. Investigator training and supervision and data monitoring were conducted by the US site (Massachusetts General Hospital, Boston)...
November 22, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29166984/a-comparison-of-musculo-articular-stiffness-and-maximal-isometric-plantar-flexion-and-knee-extension-force-in-dancers-and-untrained-individuals
#20
Paige E Rice, Herman van Werkhoven, Denzel J Dejournette, Reed D Gurchiek, John W Mackall, Jeffrey M McBride
Dance involves a high volume of aesthetic, stretch-shortening cycle (SSC) actions, which may cause unique adaptations to performance. The strength dancers possess to withstand such frequency of SSCs remains elusive. The extensive training that dancers experience from a young age, however, yields anatomical and strength development that may contrast with that of untrained individuals. Therefore, the purpose of this study was to investigate differences in musculo-articular stiffness and maximal isometric plantar flexion and knee extension force between dancers and untrained individuals...
December 15, 2017: Journal of Dance Medicine & Science
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