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https://www.readbyqxmd.com/read/27902936/how-restful-is-it-with-all-that-noise-comparison-of-interleaved-silent-steady-state-isss-and-conventional-imaging-in-resting-state-fmri
#1
J Andoh, M Ferreira, I R Leppert, R Matsushita, B Pike, R J Zatorre
Resting-state fMRI studies have become very important in cognitive neuroscience because they are able to identify BOLD fluctuations in brain circuits involved in motor, cognitive, or perceptual processes without the use of an explicit task. Such approaches have been fruitful when applied to various disordered populations, or to children or the elderly. However, insufficient attention has been paid to the consequences of the loud acoustic scanner noise associated with conventional fMRI acquisition, which could be an important confounding factor affecting auditory and/or cognitive networks in resting-state fMRI...
November 27, 2016: NeuroImage
https://www.readbyqxmd.com/read/27893618/early-resuscitation-with-lyophilized-plasma-provides-equal-neuroprotection-compared-with-fresh-frozen-plasma-in-a-large-animal-survival-model-of-traumatic-brain-injury-and-hemorrhagic-shock
#2
Ihab Halaweish, Ted Bambakidis, Vahagn C Nikolian, Patrick Georgoff, Peter Bruhn, Patryk Piascik, Lisa Buckley, Ashok Srinivasan, Baoling Liu, Yongqing Li, Hasan B Alam
BACKGROUND: Combined traumatic brain injury (TBI) and hemorrhagic shock (HS) is highly lethal. In previous models of combined TBI + HS, we showed that early resuscitation with fresh frozen plasma (FFP) improves neurologic outcomes. Delivering FFP, however, in austere environments is difficult. Lyophilized plasma (LP) is a logistically superior alternative to FFP, but data are limited regarding its efficacy for treatment of TBI. We conducted this study to determine the safety and long-term outcomes of early treatment with LP in a large animal model of TBI + HS...
December 2016: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/27891047/endoscopic-submucosal-dissection-outcomes-for-gastroesophageal-tumors-in-low-volume-units-a-multicenter-survey
#3
Ahmad Najib Azmi, Christopher J L Khor, Khek-Yu Ho, Rapat Pittayanon, Rungsun Rerknimitr, Thawee Ratanachu-Ek, Doreen S C Koay, Jianyi Calvin Koh, Shiaw-Hooi Ho, Khean-Lee Goh, Sanjiv Mahadeva
Background and Aims. Endoscopic submucosal dissection (ESD) outcomes have traditionally been reported from high volume centers in East Asia. Data from low volume centers in other parts of Asia remain sparse. Methods. A retrospective survey with a structured questionnaire of 5 tertiary centers in 3 countries in South East Asia was conducted. Details of training and clinical outcomes of ESD cases, with follow-up data from these centers, were analyzed. Results. Seven endoscopists from the 5 centers performed a total of 35 cases of ESD in the upper gastrointestinal tract (UGIT) over a 6-year duration...
2016: Diagnostic and Therapeutic Endoscopy
https://www.readbyqxmd.com/read/27889430/classification-of-teeth-in-cone-beam-ct-using-deep-convolutional-neural-network
#4
Yuma Miki, Chisako Muramatsu, Tatsuro Hayashi, Xiangrong Zhou, Takeshi Hara, Akitoshi Katsumata, Hiroshi Fujita
Dental records play an important role in forensic identification. To this end, postmortem dental findings and teeth conditions are recorded in a dental chart and compared with those of antemortem records. However, most dentists are inexperienced at recording the dental chart for corpses, and it is a physically and mentally laborious task, especially in large scale disasters. Our goal is to automate the dental filing process by using dental x-ray images. In this study, we investigated the application of a deep convolutional neural network (DCNN) for classifying tooth types on dental cone-beam computed tomography (CT) images...
November 12, 2016: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/27889277/evaluating-the-four-kallikrein-panel-of-the-4kscore-for-prediction-of-high-grade-prostate-cancer-in-men-in-the-canary-prostate-active-surveillance-study
#5
Daniel W Lin, Lisa F Newcomb, Marshall D Brown, Daniel D Sjoberg, Yan Dong, James D Brooks, Peter R Carroll, Matthew Cooperberg, Atreya Dash, William J Ellis, Michael Fabrizio, Martin E Gleave, Todd M Morgan, Peter S Nelson, Ian M Thompson, Andrew A Wagner, Yingye Zheng
BACKGROUND: Diagnosis of Gleason 6 prostate cancer can leave uncertainty about the presence of undetected aggressive disease. OBJECTIVE: To evaluate the utility of a four kallikrein (4K) panel in predicting the presence of high-grade cancer in men on active surveillance. DESIGN, SETTING, AND PARTICIPANTS: Plasma collected before the first and subsequent surveillance biopsies was assessed for 718 men prospectively enrolled in the multi-institutional Canary PASS trial...
November 23, 2016: European Urology
https://www.readbyqxmd.com/read/27888580/biology-of-vo2-max-looking-under-the-physiology-lamp
#6
REVIEW
C Lundby, D Montero, M Joyner
In this review, we argue that several key features of maximal oxygen uptake (VO2 max) should underpin discussions about the biological and reductionist determinants of its interindividual variability: (i) training-induced increases in VO2 max are largely facilitated by expansion of red blood cell volume and an associated improvement in stroke volume, which also adapts independent of changes in red blood cell volume. These general concepts are also informed by cross-sectional studies in athletes that have very high values for VO2 max...
November 7, 2016: Acta Physiologica
https://www.readbyqxmd.com/read/27885540/automatic-abdominal-multi-organ-segmentation-using-deep-convolutional-neural-network-and-time-implicit-level-sets
#7
Peijun Hu, Fa Wu, Jialin Peng, Yuanyuan Bao, Feng Chen, Dexing Kong
PURPOSE: Multi-organ segmentation from CT images is an essential step for computer-aided diagnosis and surgery planning. However, manual delineation of the organs by radiologists is tedious, time-consuming and poorly reproducible. Therefore, we propose a fully automatic method for the segmentation of multiple organs from three-dimensional abdominal CT images. METHODS: The proposed method employs deep fully convolutional neural networks (CNNs) for organ detection and segmentation, which is further refined by a time-implicit multi-phase evolution method...
November 24, 2016: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/27884677/mastery-based-virtual-reality-robotic-simulation-curriculum-the-first-step-toward-operative-robotic-proficiency
#8
Melissa E Hogg, Vernissia Tam, Mazen Zenati, Stephanie Novak, Jennifer Miller, Amer H Zureikat, Herbert J Zeh
OBJECTIVE: Hepatobiliary surgery is a highly complex, low-volume specialty with long learning curves necessary to achieve optimal outcomes. This creates significant challenges in both training and measuring surgical proficiency. We hypothesize that a virtual reality curriculum with mastery-based simulation is a valid tool to train fellows toward operative proficiency. This study evaluates the content and predictive validity of robotic simulation curriculum as a first step toward developing a comprehensive, proficiency-based pathway...
November 21, 2016: Journal of Surgical Education
https://www.readbyqxmd.com/read/27879382/veteran-preferences-regarding-wireless-management-of-positive-airway-pressure-for-obstructive-sleep-apnea-at-a-tertiary-health-care-system
#9
Ken He, Brian N Palen, Elizabeth A Mattox, Elizabeth C Parsons
BACKGROUND: Timely monitoring of obstructive sleep apnea (OSA) therapy can be a challenge amid conflicting pressures of rising patient volume and shortage of sleep medicine providers. Positive airway pressure (PAP) devices with wireless modem technology have the potential to improve patient access to care and streamline work load, yet little is known about patient attitudes toward telehealth integration among veterans with sleep apnea. As part of a larger quality improvement initiative at the Veterans Affairs (VA) Puget Sound Health Care System, we elicited veterans' preferences toward modem versus traditional PAP data download, including patient attitudes and factors affecting those preferences...
November 22, 2016: Respiratory Care
https://www.readbyqxmd.com/read/27878801/strength-training-effects-on-quality-of-prolonged-basic-cardiopulmonary-resuscitation
#10
Cristian Abelairas-Gómez, Roberto Barcala-Furelos, Łukasz Szarpak, Óscar García-García, Álvaro Paz-Domínguez, Sergio López-García, Antonio Rodríguez-Núñez
BACKGROUND: Providing high-quality chest compressions and rescue breaths are a key elements affecting the effectiveness of cardiopulmonary resuscitation (CPR). AIM: To investigate the effects of a strength training program on the quality of prolonged in time basic cardiopulmonary resuscitation on a manikin. METHODS: This was a quasi-experimental.trial. Thirty-nine participants with prior basic life support knowledge were randomized to an experimental or control group...
November 23, 2016: Kardiologia Polska
https://www.readbyqxmd.com/read/27875849/-short-and-long-term-results-in-operable-pancreatic-ductal-adenocarcinomas-from-a-cooperation-between-two-departments-gastroenterology-visceral-surgery-at-non-university-hospitals-benchmarked-to-results-of-expert-centers
#11
W Dippold, V Sivanathan, K Statt, M Roitman, K H Link
The only curative approach in pancreatic ductal adenocarcinoma (PDAC) is resection, which is possible only in 15 - 30 % of patients. Local tumor spread or distant metastases are contraindications for resection in the majority of patients. Surgical-oncological quality with short- and long-term results are varying tremendously, so that "expertise/quality" are associated to hospital- or surgeon's volume and/or center formation. The treatment results also depend, to a great extent, on the medical diagnostic quality...
November 22, 2016: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/27867696/quantification-of-extra-cerebral-and-cerebral-hemoglobin-concentrations-during-physical-exercise-using-time-domain-near-infrared-spectroscopy
#12
Héloïse Auger, Louis Bherer, Étienne Boucher, Richard Hoge, Frédéric Lesage, Mathieu Dehaes
Fitness is known to have beneficial effects on brain anatomy and function. However, the understanding of mechanisms underlying immediate and long-term neurophysiological changes due to exercise is currently incomplete due to the lack of tools to investigate brain function during physical activity. In this study, we used time-domain near infrared spectroscopy (TD-NIRS) to quantify and discriminate extra-cerebral and cerebral hemoglobin concentrations and oxygen saturation (SO2) in young adults at rest and during incremental intensity exercise...
October 1, 2016: Biomedical Optics Express
https://www.readbyqxmd.com/read/27862592/retrograde-continence-enema-in-children-with-spina-bifida-not-as-effective-as-first-thought
#13
Sebastian K King, Lefteris Stathopoulos, Loreto Pinnuck, Judy Wells, John Hutson, Yves Heloury
AIM: The aim of the study is to investigate the effectiveness of Peristeen retrograde continence enema (RCE) in the management of faecal incontinence in children with spina bifida. METHODS: We identified a homogenous group of spina bifida patients in whom RCE was initiated (Jan 2006-July 2013). Confidential assessments included (i) Fecal Incontinence Quality Of Life (FIQOL), (ii) St Marks Faecal Incontinence score, (iii) Cleveland Clinic Constipation score and (iv) Neurogenic Bowel Dysfunction score...
November 10, 2016: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/27856807/paradoxical-dissociation-between-heart-rate-and-heart-rate-variability-following-different-modalities-of-exercise-in-individuals-with-metabolic-syndrome-the-resolve-study
#14
Gil Boudet, Guillaume Walther, Daniel Courteix, Philippe Obert, Bruno Lesourd, Bruno Pereira, Robert Chapier, Agnès Vinet, Alain Chamoux, Geraldine Naughton, Paul Poirier, Frédéric Dutheil
AIMS: To analyse the effects of different modalities of exercise training on heart rate variability (HRV) in individuals with metabolic syndrome (MetS). METHODS AND RESULTS: Eighty MetS participants (aged 50-70 years) were housed and managed in an inpatient medical centre for 21 days, including weekends. Physical activity and food intake/diet were intensively monitored. Participants were randomly assigned into three training groups, differing only by intensity of exercise: moderate-endurance-moderate-resistance (re), high-resistance-moderate-endurance (Re), and moderate-resistance-high-endurance (rE)...
November 17, 2016: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/27853947/prior-video-game-utilization-is-associated-with-improved-performance-on-a-robotic-skills-simulator
#15
Andrew C Harbin, Kumar S Nadhan, James H Mooney, Daohai Yu, Joshua Kaplan, Nora McGinley-Hence, Andrew Kim, Yiming Gu, Daniel D Eun
Laparoscopic surgery and robotic surgery, two forms of minimally invasive surgery (MIS), have recently experienced a large increase in utilization. Prior studies have shown that video game experience (VGE) may be associated with improved laparoscopic surgery skills; however, similar data supporting a link between VGE and proficiency on a robotic skills simulator (RSS) are lacking. The objective of our study is to determine whether volume or timing of VGE had any impact on RSS performance. Pre-clinical medical students completed a comprehensive questionnaire detailing previous VGE across several time periods...
November 16, 2016: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/27849484/the-benefits-of-high-intensity-functional-training-fitness-programs-for-military-personnel
#16
Christopher K Haddock, Walker S C Poston, Katie M Heinrich, Sara A Jahnke, Nattinee Jitnarin
INTRODUCTION: High intensity functional training (HIFT) programs are designed to address multiple fitness domains, potentially providing improved physical and mental readiness in a changing operational environment. Programs consistent with HIFT principals such as CrossFit, SEALFIT and the US Marine Corps' High Intensity Tactical Training (HITT) are increasingly popular among military personnel. The goal of HIFT programs is to produce high levels of cardiorespiratory fitness, endurance and strength that exceed those achieved by following current physical activity recommendations...
November 2016: Military Medicine
https://www.readbyqxmd.com/read/27849115/blood-pressure-response-to-isometric-handgrip-testing-and-aerobic-capacity-and-associations-with-sprint-performance-in-middle-aged-men-following-high-intensity-interval-training
#17
Ryszard Zarzeczny, Cyprian Tomza, Anna Polak, Agnieszka Nawrat-Szołtysik
BACKGROUND: Of this study were to determine if a 6-week high-intensity interval training (HIIT) protocol with increasing exercise volume affects aerobic capacity and arterial blood pressure (BP) measured during a fatiguing isometric handgrip test (IHT) in middle-aged, normotensive men and to assess whether sprint performance is associated with training-induced changes in BP. METHODS: Fourteen recreationally active men (age 43.0 ± 0.9 years, body mass 74.4 ± 2...
November 16, 2016: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/27834031/surgeon-s-experience-overrides-the-effect-of-hospital-volume-for-postoperative-outcomes-of-laparoscopic-surgery-in-gastric-cancer-multi-institutional-study
#18
Han Hong Lee, Sang-Yong Son, Ju Hee Lee, Min Gyu Kim, Hoon Hur, Do Joong Park
BACKGROUND: Hospital volume is known to be a crucial factor in reducing postoperative morbidity and mortality in laparoscopic gastrectomy for gastric cancer. However, it is unclear whether surgeon's individual experience can overcome the effect of hospital volume. METHODS: Clinicopathologic data of initial 50 laparoscopic gastrectomy cases were collected from six gastric cancer surgeons. Half of the six surgeons worked in high-volume centers, and the other half worked in low-volume hospitals...
November 10, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27821070/association-between-novel-arterial-stiffness-indices-and-risk-factors-of-cardiovascular-disease
#19
Masaki Okamoto, Fumiaki Nakamura, Terunaga Musha, Yasuki Kobayashi
BACKGROUND: Prevention and early detection of arterial stiffness are required to avoid severe cardiovascular events. Recently, new noninvasive arterial stiffness indices, the arterial pressure volume index (API) and the arterial velocity pulse index (AVI), have been developed. The purpose of this study was to examine the clinical validity of these new indices by investigating the association between known risk factors of cardiovascular disease (CVD) and API or AVI in a large population...
November 7, 2016: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/27820726/%C3%AE-hydroxy-%C3%AE-methylbutyrate-hmb-supplementation-effects-on-body-mass-and-performance-in-elite-male-rugby-union-players
#20
Nicholas D McIntosh, Thomas D Love, Jillian Haszard, Hamish Osborne, Katherine E Black
Pre-season is characterized by high training volumes with short recovery periods β-hydroxy β-methylbutyrate (HMB) has been postulated to assist with recovery. HMB has been shown to improve strength and body composition amongst untrained groups the benefits of HMB amongst trained populations are unclear due to the methodologies employed. This randomized control trail determined the effects of 11 weeks HMB supplementation on body mass and performance measures in 27 elite rugby players. HMB group (n=13) mean±SD age 20...
October 27, 2016: Journal of Strength and Conditioning Research
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