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https://www.readbyqxmd.com/read/29342201/differentiation-of-glioblastoma-multiforme-metastases-and-primary-central-nervous-system-lymphomas-using-multiparametric-perfusion-and-diffusion-mr-imaging-of-a-tumor-core-and-a-peritumoral-zone-searching-for-a-practical-approach
#1
Małgorzata Neska-Matuszewska, Joanna Bladowska, Marek Sąsiadek, Anna Zimny
INTRODUCTION: In conventional MR examinations glioblastomas multiforme (GBMs), metastases and primary CNS lymphomas (PCNSLs) may show very similar appearance. The aim of the study was to evaluate usefulness of multiparametric T2*DSC perfusion and diffusion MR imaging in the preoperative differentiation of these tumors. MATERIAL AND METHODS: Seventy four solitary enhancing tumors (27 GBMs, 30 metastases, 17 PCNSLs) were enrolled in the study. Parameters of cerebral blood volume (rCBV), peak height (rPH), percentage of signal recovery (rPSR) and apparent diffusion coefficient (ADC) were assessed from the tumor core and the peritumoral non-enhancing T2-hyperintense zone...
2018: PloS One
https://www.readbyqxmd.com/read/29341897/toxicity-and-toxicokinetics-of-amanita-exitialis-in-beagle-dogs
#2
Jian Sun, Yu-Min Niu, Yu-Tao Zhang, Hai-Jiao Li, Yu Yin, Yi-Zhe Zhang, Pei-Bin Ma, Jing Zhou, Lie Huang, Hong-Shun Zhang, Cheng-Ye Sun
In this study, the toxicology of A. exitialis, a lethal mushroom found in China, and the toxicokinetics of peptide toxins contained in it were evaluated. Beagles were fed A. exitialis powder (20 or 60 mg/kg) in starch capsules, after which they were assessed for signs of toxicity, as well as biochemical and pathological changes. Ultra-performance liquid chromatography-electrospray ionization-tandem mass spectrometry was used to assay the peptide toxins. The total peptide toxins in A. exitialis was 3482.6 ± 124...
January 13, 2018: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/29341650/characterization-of-the-163-ho-electron-capture-spectrum-a-step-towards-the-electron-neutrino-mass-determination
#3
P C-O Ranitzsch, C Hassel, M Wegner, D Hengstler, S Kempf, A Fleischmann, C Enss, L Gastaldo, A Herlert, K Johnston
The isotope ^{163}Ho is in many ways the best candidate to perform experiments to investigate the value of the electron neutrino mass. It undergoes an electron capture process to ^{163}Dy with an energy available to the decay, Q_{EC}, of about 2.8 keV. According to the present knowledge, this is the lowest Q_{EC} value for such transitions. Here we discuss a newly obtained spectrum of ^{163}Ho, taken by cryogenic metallic magnetic calorimeters with ^{163}Ho implanted in the absorbers and operated in anticoincident mode for background reduction...
September 22, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/29340867/photoluminescent-and-thermoluminescent-studies-of-dy3-and-eu3-doped-y2o3-phosphors
#4
Tarkeshwari Verma, Sadhana Agrawal
Eu3+ doped and Dy3+ codoped yttrium oxide (Y2O3) phosphors have been prepared using solid-state reaction technique (SSR). The prepared phosphors were characterized by X-ray diffractometer (XRD), energy dispersive X-ray (EDX) spectroscopy, scanning electron microscopy (SEM) and Fourier transforms infrared spectroscopy (FTIR) techniques. Photoluminescence (PL) and Thermoluminescence (TL) properties were studied in detail. PL emission spectra were recorded for prepared phosphors under excitation wavelength 254 nm, which show a high intense peak at 613 nm for Y2O3:Dy3+, Eu3+ (1:1...
January 16, 2018: Journal of Fluorescence
https://www.readbyqxmd.com/read/29340745/a-6-week-warm-up-injury-prevention-programme-results-in-minimal-biomechanical-changes-during-jump-landings-a-randomized-controlled-trial
#5
Jeffrey B Taylor, Kevin R Ford, Randy J Schmitz, Scott E Ross, Terry A Ackerman, Sandra J Shultz
PURPOSE: To examine the extent to which an ACL injury prevention programme modifies lower extremity biomechanics during single- and double-leg landing tasks in both the sagittal and frontal plane. It was hypothesized that the training programme would elicit improvements in lower extremity biomechanics, but that these improvements would be greater during a double-leg sagittal plane landing task than tasks performed on a single leg or in the frontal plane. METHODS: Ninety-seven competitive multi-directional sport athletes that competed at the middle- or high-school level were cluster randomized into intervention (n = 48, age = 15...
January 16, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29340005/comparison-of-aerobic-performance-testing-protocols-in-elite-male-wheelchair-basketball-players
#6
Bartosz Molik, Andrzej Kosmol, Natalia Morgulec-Adamowicz, Judit Lencse-Mucha, Anna Mróz, Karol Gryko, Jolanta Marszałek
In wheelchair sports, aerobic performance is commonly assessed with the use of an arm crank ergometer (ACE), a wheelchair ergometer (WCE) or a wheelchair treadmill (WCT). There are different protocols to identify peak oxygen uptake in wheelchair sports; however, only a few protocols have been applied to evaluate these conditions in wheelchair basketball players. The purpose of this study was to compare physiological responses during maximal exercise testing with the use of ACE and WCT in wheelchair basketball players...
December 2017: Journal of Human Kinetics
https://www.readbyqxmd.com/read/29340001/neuromuscular-control-during-the-bench-press-movement-in-an-elite-disabled-and-able-bodied-athlete
#7
Artur Gołaś, Anna Zwierzchowska, Adam Maszczyk, Michał Wilk, Petr Stastny, Adam Zając
The disabled population varies significantly in regard to physical fitness, what is conditioned by the damage to the locomotor system. Recently there has been an increased emphasis on the role of competitive sport in enhancing health and the quality of life of individuals with disability. One of the sport disciplines of Paralympics is the flat bench press. The bench press is one of the most popular resistance exercises used for the upper body in healthy individuals. It is used not only by powerlifters, but also by athletes in most strength-speed oriented sport disciplines...
December 2017: Journal of Human Kinetics
https://www.readbyqxmd.com/read/29339991/multivariate-profiles-of-selected-versus-non-selected-elite-youth-brazilian-soccer-players
#8
Rodrigo Aquino, Isabella S Alves, Maickel B Padilha, Filipe Casanova, Enrico F Puggina, José Maia
This study determined whether a multivariate profile more effectively discriminated selected than non-selected elite youth Brazilian soccer players. This examination was carried out on 66 youth soccer players (selected, n = 28, mean age 16.3 ± 0.1; non-selected, n = 38, mean age 16.7 ± 0.4) using objective instruments. Multivariate profiles were assessed through anthropometric characteristics, biological maturation, tactical-technical skills, and motor performance. The Student's t-test identified that selected players exhibited significantly higher values for height (t = 2...
December 2017: Journal of Human Kinetics
https://www.readbyqxmd.com/read/29339982/relationships-between-mechanical-variables-in-the-traditional-and-close-grip-bench-press
#9
Robert G Lockie, Samuel J Callaghan, Matthew R Moreno, Fabrice G Risso, Tricia M Liu, Alyssa A Stage, Samantha A Birmingham-Babauta, John J Stokes, Dominic V Giuliano, Adrina Lazar, DeShaun L Davis, Ashley J Orjalo
The study aim was to determine relationships between mechanical variables in the one-repetition maximum (1RM) traditional bench press (TBP) and close-grip bench press (CGBP). Twenty resistance-trained men completed a TBP and CGBP 1RM. The TBP was performed with the preferred grip; the CGBP with a grip width of 95% biacromial distance. A linear position transducer measured: lift distance and duration; work; and peak and mean power, velocity, and force. Paired samples t-tests (p < 0.05) compared the 1RM and mechanical variables for the TBP and CGBP; effect sizes (d) were also calculated...
December 2017: Journal of Human Kinetics
https://www.readbyqxmd.com/read/29339701/subclinical-reduction-in-left-ventricular-function-using-triplane-and-2d-speckle-tracking-echocardiography-after-anthracycline-exposure-in-children
#10
Erman Çilsal, Ayşe Deniz Oğuz, Fatma Sedef Tunaoğlu, Serdar Kula, Ayhan Pektaş
OBJECTIVE: Speckle tracking echocardiography (STE) enables global and regional evaluation of the left ventricle (LV); therefore, it is the most useful method for detecting subclinical dysfunction in patients exposed to cardiotoxic agents. A novel technique triplane (3P) echocardiography also allows single beat assessment of LV global longitudinal strain values. We firstly aimed to demonstrate both two-dimensional (2D)- and 3PSTE-derived LV global longitudinal strain measurements in children after anthracycline exposure...
January 2018: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/29339687/subclinical-left-ventricular-systolic-dysfunction-in-patients-with-severe-aortic-stenosis-a-speckle-tracking-echocardiography-study
#11
Betül Cengiz, Şükrü Taylan Şahin, Selen Yurdakul, Serkan Kahraman, Ayşen Bozkurt, Saide Aytekin
OBJECTIVE: In patients with aortic stenosis (AS), the left ventricular (LV) geometry changes due to the increased LV afterload. However, subclinical myocardial dysfunction can develop despite a normal LV ejection fraction (EF). This study was an investigation of subclinical LV systolic dysfunction in patients with severe AS with a normal LV EF using a strain imaging method, speckle-tracking echocardiography (STE), and an evaluation of its correlation with novel indices to assess the severity of AS...
January 2018: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/29338981/reproducibility-and-agreement-of-different-non-invasive-methods-of-endothelial-function-assessment
#12
Khatera Ibrahimi, Young De Graaf, Richard Draijer, A H Jan Danser, Antoinette Maassen VanDenBrink, Anton H van den Meiracker
Flow-mediated dilatation (FMD) is an established, but investigator-demanding method, used to non-invasively determine nitric oxide (NO)-dependent endothelial function in humans. Local thermal hyperemia (LTH) or post-occlusive reactive hyperemia (PORH) of the skin measured with a laser Doppler flow imager may be a less demanding alternative of FMD. We investigated the reproducibility of the different measures of vascular function, their interrelationship and the NO-dependency of LTH. Measurements were performed twice in 27 healthy men (8 smokers), one week apart...
January 12, 2018: Microvascular Research
https://www.readbyqxmd.com/read/29338775/comparison-of-speckle-tracking-echocardiography-with-invasive-hemodynamics-for-the-detection-of-characteristic-cardiac-dysfunction-in-type-1-and-type-2-diabetic-rat-models
#13
Csaba Mátyás, Attila Kovács, Balázs Tamás Németh, Attila Oláh, Szilveszter Braun, Márton Tokodi, Bálint András Barta, Kálmán Benke, Mihály Ruppert, Bálint Károly Lakatos, Béla Merkely, Tamás Radovits
BACKGROUND: Measurement of systolic and diastolic function in animal models is challenging by conventional non-invasive methods. Therefore, we aimed at comparing speckle-tracking echocardiography (STE)-derived parameters to the indices of left ventricular (LV) pressure-volume (PV) analysis to detect cardiac dysfunction in rat models of type-1 (T1DM) and type-2 (T2DM) diabetes mellitus. METHODS: Rat models of T1DM (induced by 60 mg/kg streptozotocin, n = 8) and T2DM (32-week-old Zucker Diabetic Fatty rats, n = 7) and corresponding control animals (n = 5 and n = 8, respectively) were compared...
January 16, 2018: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/29337997/event-based-surveillance-of-middle-east-respiratory-syndrome-coronavirus-mers-cov-in-bangladesh-among-pilgrims-and-travelers-from-the-middle-east-an-update-for-the-period-2013-2016
#14
A K M Muraduzzaman, Manjur Hossain Khan, Rezina Parveen, Sharmin Sultana, Ahmed Nawsher Alam, Arifa Akram, Mahmudur Rahman, Tahmina Shirin
INTRODUCTION: Every year around 150,000 pilgrims from Bangladesh perform Umrah and Hajj. Emergence and continuous reporting of MERS-CoV infection in Saudi Arabia emphasize the need for surveillance of MERS-CoV in returning pilgrims or travelers from the Middle East and capacity building of health care providers for disease containment. The Institute of Epidemiology, Disease Control & Research (IEDCR) under the Bangladesh Ministry of Health and Family welfare (MoHFW), is responsible for MERS-CoV screening of pilgrims/ travelers returning from the Middle East with respiratory illness as part of its outbreak investigation and surveillance activities...
2018: PloS One
https://www.readbyqxmd.com/read/29337833/effects-of-plyometric-and-resistance-training-on-muscle-strength-explosiveness-and-neuromuscular-function-in-young-adolescent-soccer-players
#15
Brandon John McKinlay, Phillip Wallace, Raffy Dotan, Devon Long, Craig Tokuno, David Gabriel, Bareket Falk
This study examined the effect of 8-weeks of free-weight-resistance (RT) and plyometric (PLYO) training on maximal strength, explosiveness and jump performance compared with no added training (CON), in young male soccer players. Forty-one 11[FIGURE DASH]13-year-old soccer players were divided into three groups (RT, PLYO, CON). All participants completed isometric and dynamic (240°/s) knee extensions pre- and post-training. Peak torque (pT), peak rate of torque development (pRTD), electromechanical-delay (EMD), rate of muscle activation (Q50), m...
January 4, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29337831/the-acute-effects-of-a-caffeine-containing-supplement-on-anaerobic-power-and-subjective-measurements-of-fatigue-in-recreationally-active-males
#16
Chelsea J Hahn, Andrew R Jagim, Clayton L Camic, Matthew J Andre
Studies show mixed results for the effects of caffeine on performance, warranting further investigation. The purpose of this study was to examine the acute effects of a caffeine-containing supplement on anaerobic power and subjective measurements of fatigue during resisted sprinting on males. Fourteen recreationally-active males [N=14; (mean±SD), age: 21.0±0.7 yrs., height: 178.5±5.1 cm, weight: 77.3±9.6 kg, percent body fat: 12.6±4.8%] participated in a double-blind, placebo controlled, within-subjects crossover design study...
January 4, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29337760/using-thresholds-in-noise-to-identify-hidden-hearing-loss-in-humans
#17
Courtney L Ridley, Judy G Kopun, Stephen T Neely, Michael P Gorga, Daniel M Rasetshwane
OBJECTIVES: Recent animal studies suggest that noise-induced synaptopathy may underlie a phenomenon that has been labeled hidden hearing loss (HHL). Noise exposure preferentially damages low spontaneous-rate auditory nerve fibers, which are involved in the processing of moderate- to high-level sounds and are more resistant to masking by background noise. Therefore, the effect of synaptopathy may be more evident in suprathreshold measures of auditory function, especially in the presence of background noise...
January 15, 2018: Ear and Hearing
https://www.readbyqxmd.com/read/29337545/donor-engineering-for-nir-ii-molecular-fluorophores-with-enhanced-fluorescent-performance
#18
Qinglai Yang, Zhubin Hu, Shoujun Zhu, Rui Ma, Huilong Ma, Zhuoran Ma, Hao Wan, Tong Zhu, Zhengyan Jiang, Weiqiang Liu, Liying Jiao, Haitao Sun, Yongye Liang, Hongjie Dai
Organic fluorophores have been widely used for biological imaging in the visible and the first near-infrared windows. However, their application in the second near-infrared window (NIR-II, 1000-1700 nm) is still limited mainly due to low fluorescence quantum yields (QYs). Here, we explore molecular engineering on the donor unit to develop high performance NIR-II fluorophores. The fluorophores are constructed by a shielding unit-donor(s)-acceptor-donor(s)-shielding unit structure. Thiophene is introduced as the second donor connected to the shielding unit, which can increase the conjugation length and red-shift the fluorescence emission...
January 16, 2018: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29337197/brain-perfusion-alterations-in-tick-borne-encephalitis-preliminary-report
#19
Zuzanna Tyrakowska-Dadełło, Eugeniusz Tarasów, Dariusz Janusek, Anna Moniuszko-Malinowska, Joanna Zajkowska, Sławomir Pancewicz
BACKGROUND: Magnetic resonance imaging (MRI) changes in Tick-borne encephalitis (TBE) are nonspecific and pathophysiologic mechanisms leading to their formation remain unclear. This study aimed to investigate brain perfusion in TBE patients using dynamic susceptibility contrast (DSC) MR perfusion imaging. METHODS: MRI scans were performed in 12 patients in the acute phase, 3-5days after TBE diagnosis, with conventional MR images and DSC-MRI perfusion studies. Cerebral blood flow (CBF), cerebral blood volume (CBV), mean transit time (MTT) and time to peak (TTP) parametric maps were created...
January 11, 2018: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29337032/biohydrogen-fermentation-of-galactose-at-various-substrate-concentrations-in-an-immobilized-system-and-its-microbial-correspondence
#20
Periyasamy Sivagurunathan, Arivalagan Pugazhendhi, Gopalakrishnan Kumar, Jong-Hun Park, Sang-Hyoun Kim
The effects of substrate concentration on fermentative hydrogen production from galactose at a fixed hydraulic retention time of 12 h were investigated in an immobilized continuously stirred tank reactor. Peak hydrogen production rate and hydrogen yield of 9.57 L/L-d and 1.10 mol/mol galactoseadded, respectively, were obtained at a feed substrate concentration of 30 g/L and an organic loading rate of 60 L/L-d. Quantitative polymerase chain reaction analysis showed that the variations in the performance resulted primarily from metabolic alterations within the metabolism of the established microbial community rather than modifications in the population...
January 11, 2018: Journal of Bioscience and Bioengineering
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