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Spinal deformity

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https://www.readbyqxmd.com/read/29333123/evaluation-of-deformable-image-registration-dir-methods-for-dose-accumulation-in-nasopharyngeal-cancer-patients-during-radiotherapy
#1
Wannapha Nobnop, Imjai Chitapanarux, Hudsaleark Neamin, Somsak Wanwilairat, Vicharn Lorvidhaya, Taweap Sanghangthum
Introduction: Deformable image registration (DIR) is used to modify structures according to anatomical changes for observing the dosimetric effect. In this study, megavoltage computed tomography (MVCT) images were used to generate cumulative doses for nasopharyngeal cancer (NPC) patients by various DIR methods. The performance of the multiple DIR methods was analysed, and the impact of dose accumulation was assessed. Patients and methods: The study consisted of five NPC patients treated with a helical tomotherapy unit...
December 2017: Radiology and Oncology
https://www.readbyqxmd.com/read/29330576/xipho-pubic-angle-xpa-correlates-with-patient-s-reported-outcomes-in-a-population-of-adult-spinal-deformity-results-from-a-multi-center-cohort-study
#2
Francesco Langella, Jorge Hugo Villafañe, Virginie Lafage, Justin S Smith, Christopher Shaffrey, Han Jo Kim, Douglas Burton, Richard Hostin, Shay Bess, Christopher Ames, Gregory Mundis, Eric Klineberg, Frank Schwab, Renault Lafage, Pedro Berjano
STUDY DESIGN: Retrospective multi-center cohort study. PURPOSE: Sagittal misalignment causes changes in the abdominal shape. Xipho-pubic angle (XPA) has been previously described to radiographically evaluate the shape of the abdominal cavity in patients with spine deformity. The aims of this study are to evaluate the correlation of XPA-to-spinopelvic sagittal parameters and to patients' health-related quality-of-life (HRQoL) scores. METHODS: 278 patients from a multi-center database with diagnosis adult spinal deformity (ASD) (one or more of: coronal Cobb angle > 20°, sagittal vertical axis (SVA) > 50 mm, pelvic tilt (PT) > 25°, and thoracic kyphosis > 60°) were included...
January 12, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29326761/prevalence-rate-of-adolescent-idiopathic-scoliosis-results-of-school-based-screening-in-surabaya-indonesia
#3
I S Komang-Agung, S B Dwi-Purnomo, A Susilowati
Introduction: Scoliosis is a lateral spinal deformity of 10 degrees or more, resulting in a C-shaped or S-shaped curve of the spine. Information about adolescent idiopathic scoliosis (AIS) prevalence rate is important not only for paediatric health care planning strategy but also for parent's awareness. This study aims to find the suitable inclination cut-off angle and the prevalence rate of AIS in Surabaya, Indonesia. Materials and Methods: This is a descriptive cross-sectional study conducted in 2010. We performed stratified random sampling of 784 Elementary and Junior High School students in Surabaya between 9-16 years of age...
November 2017: Malaysian Orthopaedic Journal
https://www.readbyqxmd.com/read/29323733/photo-induced-toxicity-following-exposure-to-crude-oil-and-ultraviolet-radiation-in-two-australian-fishes
#4
Lauren E Sweet, Andrew T Revill, Joanna Strzelecki, Sharon E Hook, Jeffrey M Morris, Aaron P Roberts
Some polycyclic aromatic hydrocarbons (PAHs), a component of crude oil, are known to cause increased toxicity when organisms are co-exposed with ultraviolet radiation, resulting in photo-induced toxicity. The photodynamic characteristic of some PAHs are of particular concern to places like Australia with high ultraviolet radiation levels. The objective of this study was to characterize the photo-induced toxicity of an Australian Northwest Shelf oil to early life stage yellowtail kingfish (Seriola lalandi) and black bream (Acanthopagrus butcheri)...
January 11, 2018: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/29320988/prevalence-and-key-radiographic-spinal-malalignment-parameters-that-influence-the-risk-for-gastroesophageal-reflux-disease-in-patients-treated-surgically-for-adult-spinal-deformity
#5
Tetsuro Ohba, Shigeto Ebata, Kensuke Koyama, Hirotaka Haro
BACKGROUND: Gastroesophageal reflux disease (GERD) is a factor that has a significant negative impact on the quality of life (QoL). Vertebral fractures and/or spinal malalignment may influence the frequency of GERD. However, the epidemiology and pathology of GERD in patients with adult spinal deformity (ASD) are still largely unknown. To establish the optimal surgical strategy for GERD in patients treated surgically for ASD, we sought to clarify the GERD prevalence, determine radiographically which spinal malalignment parameters influence GERD risk, and evaluate GERD improvement postoperatively...
January 10, 2018: BMC Gastroenterology
https://www.readbyqxmd.com/read/29318414/accuracy-of-pedicle-screw-insertion-by-airo%C3%A2-intraoperative-ct-in-complex-spinal-deformity-assessed-by-a-new-classification-based-on-technical-complexity-of-screw-insertion
#6
S Rajasekaran, Manindra Bhushan, Siddharth Aiyer, Rishi Kanna, Ajoy Prasad Shetty
PURPOSE: To develop a classification based on the technical complexity encountered during pedicle screw insertion and to evaluate the performance of AIRO® CT navigation system based on this classification, in the clinical scenario of complex spinal deformity. MATERIALS AND METHODS: 31 complex spinal deformity correction surgeries were prospectively analyzed for performance of AIRO® mobile CT-based navigation system. Pedicles were classified according to complexity of insertion into five types...
January 9, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29315120/ethnic-variations-in-radiographic-parameters-and-srs-22-scores-in-adult-spinal-deformity-a-comparison-between-north-american-and-japanese-patients-above-50-years-of-age-with-minimum-2-year-follow-up
#7
Naobumi Hosogane, Christopher Ames, Morio Matsumoto, Mitsuru Yagi, Yukihiro Matsuyama, Hiroshi Taneichi, Yu Yamato, Daisaku Takeuchi, Frank Schwab, Christopher Shaffrey, Justin S Smith, Shay Bess, Virginie Lafage
STUDY DESIGN: Retrospective review of North American and Japanese adult spinal deformity (ASD) database. OBJECTIVE: To investigate the ethnical differences in radiographic parameters and Scoliosis Research Society (SRS)-22 between North American and Japanese ASD. SUMMARY OF BACKGROUND DATA: Previous comparison study between North American and Japanese ASD patients has revealed Japanese patients had marked pelvic tilt deformity and had lower Oswestry Disability Index scores corresponding to established thresholds of radiographic deformity...
January 8, 2018: Clinical Spine Surgery
https://www.readbyqxmd.com/read/29312839/safety-and-efficacy-of-the-use-of-intrathecal-morphine-for-spinal-three-column-osteotomy
#8
Jason R Audlin, Swamy Kurra, William Lavelle, Richard A Tallarico, Mike H Sun, Nathaniel R Ordway, Elizabeth A Demers Lavelle
Introduction The use of intrathecal morphine has the potential to help alleviate the pain that patients experience undergoing spinal surgeries. Complications can cause immobilization, which can lead to vascular thrombosis and ileus. Studies have shown epidural analgesia significantly lowered postoperative pain scores in scoliosis surgeries. Intrathecal anesthesia has been shown to have good pain control over the initial 24-hour postoperative period. Purpose Determine if intrathecal morphine would reduce postoperative pain with minimal side effects...
November 3, 2017: Curēus
https://www.readbyqxmd.com/read/29311012/anesthetic-management-of-mosaic-turner-s-syndrome-posted-for-elective-cesarean-delivery-after-spontaneous-pregnancy
#9
K Kalopita, L Michala, C Theofanakis, D Valsamidis
Turner's syndrome, one of the most common sex chromosome abnormalities in females, is caused by loss of part or all of an X chromosome. We report a case of mosaic Turner's syndrome, posted for elective cesarean delivery under low-dose sequential combined spinal epidural anesthesia. The unique features of this case were the combination of an anticipated difficult airway and both short stature and scoliosis in the lumbar region. A titrated combined spinal-epidural technique was performed in order to avoid hemodynamic instability, which could have been exacerbated in the presence of cardiovascular deformities that accompany this syndrome in many cases...
November 26, 2017: International Journal of Obstetric Anesthesia
https://www.readbyqxmd.com/read/29310921/does-patients-perception-of-leg-length-after-total-hip-arthroplasty-correlate-with-anatomical-leg-length
#10
Jean Y Lazennec, Dominique Folinais, Caroline Florequin, Aidin E Pour
BACKGROUND: This study assessed the correlation among the patients' perception of the leg length discrepancy (LLD) after total hip arthroplasty (THA) and the anatomical and functional leg length, pelvic and knee alignments, and foot height. METHODS: Patients without significant spinal pathology or previous spine or lower extremity surgery who underwent primary THA (101 patients) were evaluated using EOS images obtained in standing position. All 3-dimensional measures were evaluated and compared for the repeatability and reproducibility and correlation with patients' perception of leg length...
December 13, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29310355/revision-surgery-for-lumbar-hemivertebra-in-a-7-year-old-child-with-10-year-follow-up-a-case-report-a-care-compliant-article
#11
Xuhong Xue, Sheng Zhao
RATIONALE: Hemivertebrae, which are the most frequent cause of congenital scoliosis, pose a challenge in terms of prognosis and therapy. The current gold standard treatment congenital scoliosis due to a lumbar and thoracic hemivertebra would be hemivertebra resection and short level posterior spinal fusion. Paucity literatures are reported for the treatment of hemivertebra by convex fusion with posterior hemivertebra excision. PATIENT CONCERNS: The patient was first noticed to have a spinal problem at 7 years of age...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29301171/proximal-junctional-kyphosis-and-proximal-junctional-failure-following-adult-spinal-deformity-surgery
#12
REVIEW
Seung-Jae Hyun, Byoung Hun Lee, Jong-Hwa Park, Ki-Jeong Kim, Tae-Ahn Jahng, Hyun-Jib Kim
The purpose of this review is the current understanding of proximal junctional kyphosis (PJK) and proximal junctional failure (PJF) following adult spinal deformity (ASD) surgery. We carried out a systematic search of PubMed for literatures published up to September 2017 with "proximal junctional kyphosis," "proximal junctional failure," and "adult spinal deformity" as search terms. A total of 98 literatures were searched. The 37 articles were included in this review. PJK is multifactorial in origin and likely results from variable risk factors...
December 2017: Korean Journal of Spine
https://www.readbyqxmd.com/read/29300250/postoperative-disability-after-long-corrective-fusion-to-the-pelvis-in-elderly-patients-with-spinal-deformity
#13
Daisuke Togawa, Tomohiko Hasegawa, Yu Yamato, Go Yoshida, Sho Kobayashi, Tatsuya Yasuda, Shin Oe, Tomohiro Banno, Hideyuki Arima, Yuki Mihara, Hiroki Ushirozako, Yukihiro Matsuyama
STUDY DESIGN: Prospective case series analysis. OBJECTIVE: The purpose of this study was to investigate the degree of difficulty in daily activities of adult spinal deformity (ASD) patients after corrective long fusion to the pelvis, with emphasis on bend forward activities. SUMMARY OF BACKGROUND DATA: No prospective studies have been reported regarding the postoperative impairments and their time course after long fusion in ASD patients. METHODS: One-hundred-three patients (26 men, 77 women; mean age 68 [50-82]) who underwent corrective long fusion from the thoracic spine to the pelvis were included...
January 3, 2018: Spine
https://www.readbyqxmd.com/read/29299490/osteoporosis-and-the-management-of-spinal-degenerative-disease-ii
#14
REVIEW
Félix Tomé-Bermejo, Angel R Piñera, Luis Alvarez
Osteoporosis has become a major medical problem as the aged population of the world rapidly grows. Osteoporosis predisposes patients to fracture, progressive spinal deformities, and stenosis, and is subject to be a major concern before performing spine surgery, especially with bone fusions and instrumentation. Osteoporosis has often been considered a contraindication for spinal surgery, while in some instances patients have undergone limited and inadequate procedures in order to avoid concomitant instrumentation...
November 2017: Archives of Bone and Joint Surgery
https://www.readbyqxmd.com/read/29299476/have-the-annual-trends-of-total-knee-arthroplasty-in-ankylosing-spondylitis-patients-decreased
#15
Roby Abraham, John J Kelly, Jared M Newman, Qais Naziri, Nipun Sodhi, Anton Khlopas, Jaiben George, Neil V Shah, Assem A Sultan, Morad Chughtai, John W Barrington, Carl B Paulino, Michael A Mont
Background: Ankylosing spondylitis (AS) is characterized by osteoproliferation-induced structural damage and spinal inflammation, which lead to spinal deformity and functional disability. Though AS commonly affects the axial skeleton and sacroiliac joints, up to 70% of patients have involvement of the knees and other joints. Despite pharmacological efforts, advancing joint involvement may ultimately require surgical intervention. Total knee arthroplasty (TKA) is effective in managing patients with AS, yet it remains unclear whether or not the annual rates of TKA have been affected...
December 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/29290050/osteotomies-in-ankylosing-spondylitis-where-how-many-and-how-much
#16
REVIEW
H Koller, M Mayer, A Hempfing, J Koller
INTRODUCTION: This article presents the current concepts of correction of spinal deformity in ankylosing spondylitis (AS) patients. Untreated AS can be a debilitating disease. In a few patients, disease progression results in severe spinal deformity affecting not only the thoracolumbar, but also the cervical spine. Surgery for correction in AS patients has a long history. With the advent of modern instrumentation, standardization of surgical and anesthesiologic techniques, surgical safety and corrective results could be improved and experiences from lumbar osteotomies could be transferred to the cervical spine...
December 30, 2017: European Spine Journal
https://www.readbyqxmd.com/read/29287823/posterior-only-vertebral-column-resection-for-fused-spondyloptosis
#17
Jeffrey L Gum, Lawrence G Lenke, Anand Mohapatra, Sam Q Sun, Michael P Kelly
STUDY DESIGN: Retrospective review. OBJECTIVES: To describe 3 cases of a posterior-only vertebral column resection (pVCR) for the treatment of spondyloptosis in the setting of prior spinal fusions. SUMMARY OF BACKGROUND DATA: Lumbosacral spondyloptosis is a rare spinal deformity with a number of surgical options, none of which demonstrate clear superiority. The use of an L5 vertebral column resection, via combined anterior and posterior approaches, to restore lumbosacral alignment has been described though is accompanied by high rates of neurological deficit...
January 2018: Spine Deformity
https://www.readbyqxmd.com/read/29287822/srs-22r-minimum-clinically-important-difference-and-substantial-clinical-benefit-after-adult-lumbar-scoliosis-surgery
#18
Leah Y Carreon, Michael P Kelly, Charles H Crawford, Christine R Baldus, Steven D Glassman, Christopher I Shaffrey, Keith H Bridwell
STUDY DESIGN: Longitudinal cohort. OBJECTIVES: To determine if the minimum clinically important difference (MCID) and substantial clinical benefit (SCB) thresholds for the Scoliosis Research Society-22R (SRS22R) domains in patients with degenerative lumbar scoliosis are similar to those in patients with adult spinal deformity (ASD) with fusions extending into the thoracic spine. SUMMARY OF BACKGROUND DATA: The MCID and SCB thresholds for the SRS22R domains in patients with ASD and adolescent idiopathic scoliosis have been reported...
January 2018: Spine Deformity
https://www.readbyqxmd.com/read/29287820/health-related-quality-of-life-scores-underestimate-the-impact-of-major-complications-in-lumbar-degenerative-scoliosis-surgery
#19
Steven D Glassman, Keith H Bridwell, Christopher I Shaffrey, Charles C Edwards, Jon D Lurie, Christine R Baldus, Leah Y Carreon
STUDY DESIGN: Retrospective cohort. OBJECTIVE: To examine Charlson Comorbidity Index (CCMI) as a marker for deterioration in health status not reflected in standard Health Related Quality of Life (HRQOL) measures. SUMMARY OF BACKGROUND DATA: HRQOL has become a primary metric for assessing outcomes following spinal deformity surgery. However, studies have reported limited impact of complications on postoperative HRQOL outcomes. METHODS: We examined serial CCMI, complications, and HRQOL outcomes for 138 adult lumbar deformity patients treated surgically with a minimum two-year follow-up that included 126 females (91%) with a mean age of 59...
January 2018: Spine Deformity
https://www.readbyqxmd.com/read/29287819/adult-spinal-deformity-knowledge-in-orthopedic-spine-surgeons-impact-of-fellowship-training-experience-and-practice-characteristics
#20
Zachary J Grabel, Robert A Hart, Aaron P Clark, Sara Heejung Park, Christopher I Shaffrey, Justin K Scheer, Justin S Smith, Michael P Kelly, J Mason DePasse, Munish C Gupta, Christopher P Ames, Alan H Daniels
STUDY DESIGN: Survey study. OBJECTIVE: The purpose of this paper was to assess the level of adult spine deformity (ASD) knowledge among orthopedic spine surgeons and identify areas for improvement in spine surgery training. SUMMARY OF BACKGROUND DATA: ASD is increasingly encountered in spine surgery practice. While ASD knowledge among neurosurgeons has been evaluated, ASD knowledge among orthopedic spine surgeons has not previously been reported...
January 2018: Spine Deformity
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