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https://www.readbyqxmd.com/read/28638933/-implementation-status-of-regulation-eu-536-2014-in-the-member-states
#1
REVIEW
Elke Stahl
The upcoming Regulation EU 536/2014 for clinical trials of medicinal products for human use requires multinational cooperation in the assessment of clinical trial applications by the member states concerned as well as one single decision per member state concerned, supported by the new EU Portal and database system. The implementation makes national reorganisation of the processes necessary, especially coordination and cooperation between the national competent authorities and the ethics committees, necessary...
June 21, 2017: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/28626749/a-century-spent-combating-rabies-in-morocco-1911-2015-how-much-longer
#2
Sami Darkaoui, Florence Cliquet, Marine Wasniewski, Emmanuelle Robardet, Nadia Aboulfidaa, Mohammed Bouslikhane, Ouafaa Fassi-Fihri
Rabies has no known beginning in Morocco and to date, government control efforts and plans fail to eradicate the disease. A review and analysis of available epidemiological data are crucial to learn lessons from the past and to propose effective actions. Legally, animal rabies is a notifiable disease since 1913 and legislation has been updated periodically since. Dogs have always been considered as both the disease's vector and reservoir, while cattle, other herbivores, and humans are victims. Animal rabies cases evolution from 1942 to 2015 is characterized by ascending phase then decreasing one following structured rabies control plan implementation in 1980s...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/28614506/health-work-portrait-of-community-workers-in-the-northeast-region-of-brazil
#3
Paloma Ribeiro Pires Simas, Isabela Cardoso de Matos Pinto
The aim of this study was to characterize the profile of community health workers in northeastern Brazil and aspects related to the management of their work. This is a cross-sectional study, which included 535 community agents who were distributed in 107 primary health units in northeastern Brazil. The data were extracted from eight blocks of questions related to the community agents' perceptions about social-demographic, economic and political factors; their contracts and remuneration; their evaluation as workers; their working conditions and their training...
June 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28612900/italian-law-on-the-vehicular-homicide-medical-legal-issues-and-comparative-analysis
#4
G Montanari Vergallo, E Marinelli, N M di Luca, V Masotti, R Cecchi, S Zaami
Law no. 41/2016, enacted after a parliamentary debate characterized by a strong media pressure, intends to give a strong response to the growing social alarm caused by road accidents causing deaths. In this perspective, it introduced the categories of road homicide and road injuries within the Penal Code and the new hypotheses of mandatory and facultative arrest in flagrante delicto. This paper aims at comparing the rules by which the United Kingdom, France, Spain, Germany and Italy protect people's lives and safety of vehicular traffic in order to highlight strengths and weaknesses with a view to future reforms...
May 2017: La Clinica Terapeutica
https://www.readbyqxmd.com/read/28596675/cautiously-using-natural-medicine-to-treat-liver-problems
#5
EDITORIAL
Fei Xiong, Yong-Song Guan
Natural medicine is a system of therapy that administrates natural agents and their derivatives to treat human diseases. This medicine has been used to treat many kinds of human diseases for thousands of years. The treatment protocols of natural medicine are integrative in nature, and are required to utilize the most appropriate therapies to address the needs of the individual patient. Because of the relative convenience, safety and efficacy, natural medicine is now increasing worldwide. Naturopathic doctors are licensed in many areas of the world and regulated partly by law in these areas, which is quite different from various other forms of complementary and alternative medicine...
May 21, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28592711/occupational-violence-in-pregnant-women-in-brazil-a-sample-of-cases-in-the-labor-court
#6
Bárbara de Oliveira Turatti, Rodrigo Otávio Moretti-Pires
Brazilian women are still a recurring target of discrimination in the workplace, facing violence related to gender relations and moral harassment, especially when they are pregnant. When the worker perceives discriminatory acts and attitudes or any violation of the rights guaranteed by law, she may appeal to the Labor Court to initiate legal action. This in turn exposes the worker to a number of issues, such as workplace persecution and future dismissal. The rights of pregnant women to temporary stability, free time for medical examinations, change of duties and maternity leave contrast with the usurpation of the administration's workforce...
June 7, 2017: Journal of Occupational Health
https://www.readbyqxmd.com/read/28580580/illicit-drug-delivery-via-administration-of-human-blood
#7
Laura M Labay, Charles A Catanese
The physiological, psychological, and social consequences associated with illicit drug use are well documented. In addition to the effects directly related to the drug(s), the delivery mechanism can precipitate other serious health conditions. A case is reported where an individual stopped by law enforcement was discovered to be in possession of a vial containing a red-colored fluid, which the person stated was blood and contained fentanyl. Analysis by headspace GC, ELISA, and LC-TOF/MS screening in with mass spectral confirmation revealed the presence of several substances, including ethanol, methamphetamine, amphetamine, MDA, 6-monoacetylmorphine, codeine, morphine, alprazolam, delta-9 THC, ephedrine, pseudoephedrine, and norpseudoephedrine; serology testing verified the fluid was consistent with human blood...
June 5, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28579820/cannabis-and-intractable-chronic-pain-an-explorative-retrospective-analysis-of-italian-cohort-of-614-patients
#8
Guido Fanelli, Giuliano De Carolis, Claudio Leonardi, Adele Longobardi, Ennio Sarli, Massimo Allegri, Michael E Schatman
BACKGROUND: Despite growing interest in the therapeutic use of cannabis to manage chronic pain, only limited data that address these issues are available. In recent years, a number of nations have introduced specific laws to allow patients to use cannabis preparations to treat a variety of medical conditions. In 2015, the Italian government authorized the use of cannabis to treat several diseases, including chronic pain generally, spasticity in multiple sclerosis, cachexia and anorexia among AIDS and cancer patients, glaucoma, Tourette syndrome, and certain types of epilepsy...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28573964/a-place-in-the-sun-healthcare-rights-of-retired-uk-citizens-in-spain-post-brexit
#9
Joaquin Cayon-De Las Cuevas, Tamara Hervey
At least 100,000 retired UK citizens currently live in Spain. Under EU law, they are entitled to access the Spanish National Health Service (NHS) with minimum administrative difficulty. What will their legal position be under a 'no-deal Brexit'? This is a question of Spanish law. The worst case scenario is that they will have to reapply for their residence permits under the Spanish legislation applicable to non-EU/European Economic Area citizens, with all the administrative inconvenience and cost entailed. If they successfully reapply, their personal health care costs will be considerably higher than at present, should they choose to remain in Spain...
July 2017: Health Economics, Policy, and Law
https://www.readbyqxmd.com/read/28554214/battling-the-chargemaster-a-simple-remedy-to-balance-billing-for-unavoidable-out-of-network-care
#10
Barak D Richman, Nick Kitzman, Arnold Milstein, Kevin A Schulman
OBJECTIVES: To develop an effective legal mechanism to combat chargemaster abuses and to facilitate price transparency. STUDY DESIGN: Applying legal doctrines to out-of-network (OON) billing disputes. METHODS: We reviewed rudimentary contract law and examined the law's handling of contracts where prices have not been specified in advance. These cases are the controlling authority to guide courts, handling of surprise and OON billing problems...
April 1, 2017: American Journal of Managed Care
https://www.readbyqxmd.com/read/28553183/an-evaluation-of-deviation-from-the-international-atomic-energy-agency-international-commission-on-radiological-protection-proposed-equation-for-calculation-of-radiation-dose-rate-emanating-from-the-patients-with-differentiated-thyroid-cancer-undergoing-radioiodine
#11
Forough Jafarian Dehkordi, Behrouz Rasuli, Ali Mahmoud-Pashazadeh
The main purpose of this study was to investigate dose rate emanating from patients treated with (131)I to evaluate which of the theoretical formulas, inverse-square law (ISL) and International Atomic Energy Agency-International Commission on Radiological Protection (IAEA-ICRP) suggested equation, can provide a sufficiently close approximation of the measured dose rate. Measurements were performed based on the IAEA safety report No. 63 method at 0, 12, 24, and 48 h after administration of radioiodine at a distance of 1 m for 69 patients and for the rest of 67 patients, dose rate was measured at 2, 4, 24, and 48 h at a distance of 2 m...
April 2017: World Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28551534/tracing-methamphetamine-and-amphetamine-sources-in-wastewater-and-receiving-waters-via-concentration-and-enantiomeric-profiling
#12
Zeqiong Xu, Peng Du, Kaiyang Li, Tingting Gao, Zhenglu Wang, Xiaofang Fu, Xiqing Li
Wastewater analysis is a promising approach to monitor illicit drug abuse of a community. However, drug use estimation via wastewater analysis may be biased by sources other than abuse. This is especially true for methamphetamine and amphetamine as their presence in wastewater may come from many sources, such as direct disposal or excretion following administration of prescription drugs. Here we traced methamphetamine and amphetamine sources via concentration and enantiomeric profiling of the two compounds from black market to receiving waters...
May 25, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28544336/regulation-of-controlled-substance-prescribing-an-overview-for-certified-nurse-midwives-and-certified-midwives
#13
Kathryn Osborne
In addition to the regulation of prescriptive authority and prescribing practices conducted by individual states, the prescription of controlled substances is also regulated at the federal level by the US Drug Enforcement Administration (DEA). While there are variations in state laws relative to controlled substance prescribing, federal law is uniform across states as established by the Controlled Substances Act (21 United States Code § 801-890) and the DEA Regulations (Title 21, Code of Federal Regulations)...
May 2017: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/28539104/development-of-collaborative-drug-therapy-management-and-clinical-pharmacy-services-in-an-outpatient-psychiatric-clinic
#14
Ashley Tewksbury, Kevin M Bozymski, Laura Ruekert, Cheen Lum, Elizabeth Cunningham, Frank Covington
Collaborative drug therapy management (CDTM) is a written agreement that allows a pharmacist to initiate, modify, or continue pharmacotherapies under a physician's scope of practice. While available literature pertaining to cardiometabolic and respiratory CDTM services is growing, publications are sparse in psychiatry, particularly outside Veterans Health Administration medical centers. A descriptive study was undertaken to demonstrate how a board-certified psychiatric pharmacist would begin organizing a protocol for clinical pharmacy services at an outpatient, community treatment center for mental health and substance abuse disorders...
January 1, 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28530047/what-is-it-going-to-take-to-move-youth-related-hiv-programme-policies-into-practice-in-africa
#15
Daniella Mark, Lina Taing, Lucie Cluver, Chris Collins, Kate Iorpenda, Catarina Andrade, Luann Hatane
INTRODUCTION: HIV has been reported to be the leading cause of mortality amongst adolescents in Africa. This has brought attention to the changes in service provision and health management that many adolescents living with HIV experience when transferring from specialized paediatric- or adolescent-focused services to adult care. When transition is enacted poorly, adherence may be affected and the continuum of care disrupted. As the population of HIV-infected adolescents grows, effective and supported transition increases in significance as an operational imperative...
May 16, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28520927/preoperative-stratification-of-transsphenoidal-pituitary-surgery-patients-based-on-surgical-urgency
#16
Hasan A Zaidi, Amy J Wang, David J Cote, Timothy R Smith, Daniel Prevedello, Domenico Solari, Paolo Cappabianca, Monica Quiroga, Edward R Laws
BACKGROUND: Currently, there is no prioritization scale available to distinguish those patients with pituitary tumors who require urgent surgical intervention from those who are candidates for elective treatment. OBJECTIVE: To develop a classification system that can help primary care physicians, endocrinologists, neurosurgeons, ancillary support staff, and hospital administrators identify high-priority surgical candidates. METHODS: An expert international panel of clinicians consisting of endocrinologists and neurosurgeons who are involved in the diagnosis and management of sellar disease was convened...
May 18, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28507222/meeting-the-goal-of-concurrent-adolescent-and-adult-licensure-of-hiv-prevention-and-treatment-strategies
#17
Michelle Hume, Linda L Lewis, Robert M Nelson
The ability of adolescents to access safe and effective new products for HIV prevention and treatment is optimised by adolescent licensure at the same time these products are approved and marketed for adults. Many adolescent product development programmes for HIV prevention or treatment products may proceed simultaneously with adult phase III development programmes. Appropriately implemented, this strategy is not expected to delay licensure as information regarding product efficacy can often be extrapolated from adults to adolescents, and pharmacokinetic properties of drugs in adolescents are expected to be similar to those in adults...
May 15, 2017: Journal of Medical Ethics
https://www.readbyqxmd.com/read/28499474/-legislative-evolution-and-regulatory-framework-of-child-placement
#18
Jean Moineville
In the area of child protection, French law has evolved considerably over recent decades. Leal texts provide the system with a very precise structure, in order to organise child protection on an administrative and judicial level.
May 2017: Soins. Pédiatrie, Puériculture
https://www.readbyqxmd.com/read/28497945/clarification-of-employer%C3%A2-s-continuing-obligation-to-make-and-maintain-an-accurate-record-of-each-recordable-injury-and-illness-final-rule
#19
(no author information available yet)
Under the Congressional Review Act, Congress has passed, and the President has signed, Public Law 115-21, a resolution of disapproval of OSHA's final rule titled, "Clarification of Employer's Continuing Obligation to Make and Maintain an Accurate Record of each Recordable Injury and Illness." OSHA published the rule, which contained various amendments to OSHA's recordkeeping regulations, on December 19, 2016. The amendments became effective on January 18, 2017. Because Public Law 115-21 invalidates the amendments to OSHA's recordkeeping regulations contained in the rule promulgated on December 19, 2016, OSHA is hereby removing those amendments from the Code of Federal Regulations...
May 3, 2017: Federal Register
https://www.readbyqxmd.com/read/28495109/health-and-health-care-in-israel-an-introduction
#20
REVIEW
A Mark Clarfield, Orly Manor, Gabi Bin Nun, Shifra Shvarts, Zaher S Azzam, Arnon Afek, Fuad Basis, Avi Israeli
Starting well before Independence in 1948, and over the ensuing six decades, Israel has built a robust, relatively efficient public system of health care, resulting in good health statistics throughout the life course. Because of the initiative of people living under the British Mandate for Palestine (1922-48), the development of many of today's health services predated the state's establishment by several decades. An extensive array of high-quality services and technologies is available to all residents, largely free at point of service, via the promulgation of the 1994 National Health Insurance Law...
May 5, 2017: Lancet
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