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Acute coronary syndrome.TAVI

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https://www.readbyqxmd.com/read/27396607/incidence-feasibility-and-outcome-of-percutaneous-coronary-intervention-after-transcatheter-aortic-valve-implantation-with-a-self-expanding-prosthesis-results-from-a-single-center-experience
#1
Abdelhakim Allali, Mohamed El-Mawardy, Bettina Schwarz, Takao Sato, Volker Geist, Ralph Toelg, Gert Richardt, Mohamed Abdel-Wahab
OBJECTIVES: Percutaneous coronary intervention (PCI) after transcatheter aortic valve implantation (TAVI) can become technically challenging after implantation of the self-expanding Medtronic CoreValve (MCV) device, which completely covers the aortic root. The aim of this study was to report on the incidence, feasibility and outcome of PCI after TAVI with the MCV device. METHODS: Between 2007 and 2014, all patients subjected to PCI after MCV implantation in a single-center institutional TAVI database were retrospectively identified...
September 2016: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/26716594/bail-out-use-of-impella-cp-as-a-bridge-to-tavi-in-a-cardiogenic-shock-patient-the-pump-rewiring-technique
#2
Francesco Burzotta, Roberto Nerla, Carlo Trani
BACKGROUND: The optimal management of cardiogenic shock (CS) occurring in the presence of acute coronary syndromes, severe aortic stenosis, and poor left ventricular function has not been established. Recently, the availability of new assistance devices and techniques has provided novel management opportunities. In particular, when compared with surgical approaches, percutaneous procedures have the advantage of allowing "staged" interventions, in which different steps are planned according to the patient's evolving clinical conditions...
January 2016: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/26642781/antiplatelet-agents-in-cardiology-a-report-on-aspirin-clopidogrel-prasugrel-and-ticagrelor
#3
Paul P Dobesh, Sara Varnado, Meagan Doyle
Antiplatelet drugs are the cornerstone of therapy in many cardiovascular conditions. With the current success and increased use of transcatheter aortic valve implantation (TAVI), the use of antiplatelet therapy is considered part of the medical therapy for these patients. Clinicians caring for these patients need to have a thorough understanding of the pharmacology, pharmacokinetics, pharmacodynamic, and clinical efficacy and safety of commonly used antiplatelet therapy. While aspirin therapy is widely used, dual antiplatelet therapy with clopidogrel has become part of standard of care...
2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/25948421/antiplatelet-therapy-following-transcatheter-aortic-valve-implantation
#4
REVIEW
Mariëlla E C J Hassell, David Hildick-Smith, Eric Durand, Wouter J Kikkert, Esther M A Wiegerinck, Eugenio Stabile, Gian Paolo Ussia, Sumeet Sharma, Jan Baan, Hélène Eltchaninoff, Paolo Rubino, Marco Barbanti, Corrado Tamburino, Petra Poliacikova, Didier Blanchard, Jan J Piek, Ronak Delewi
OBJECTIVE: There is limited evidence to support decision making on antiplatelet therapy following transcatheter aortic valve implantation (TAVI). Our aim was to assess the efficacy and safety of aspirin-only (ASA) versus dual antiplatelet therapy (DAPT) following TAVI. METHODS: We performed a systematic review and pooled analysis of individual patient data from 672 participants comparing single versus DAPT following TAVI. Primary endpoint was defined as the composite of net adverse clinical and cerebral events (NACE) at 1 month, including all-cause mortality, acute coronary syndrome (ACS), stroke, life-threatening and major bleeding...
July 2015: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/23956980/pharmacodynamic-effect-of-clopidogrel-in-patients-undergoing-transcatheter-aortic-valve-implantation
#5
Petr Tousek, Viktor Kocka, Jakub Sulzenko, Frantisek Bednar, Hana Linkova, Petr Widimsky
The aim of this study was to analyze periprocedural and mid-term effect of clopidogrel on platelet function using the VerifyNow P2Y12 point-of-care assay in patients undergoing TAVI. Platelet reactivity was measured at the beginning of the procedure after 300 mg clopidogrel bolus administration and during the follow-up (at 1 month after the procedure) in 52 patients undergoing TAVI using the Medtronic CoreValve prosthesis (Medtronic CoreValve). A cutoff value of 240 PRU was used to identify nonresponders to clopidogrel treatment with high residual platelet reactivity (HRPR)...
2013: BioMed Research International
https://www.readbyqxmd.com/read/22777872/percutaneous-coronary-intervention-in-tavi-the-proboscis-catheter
#6
Massimo Mancone, Mauro Pennacchi, Gennaro Sardella
We report a case of an 81-years-old male, recently implanted with a Core Valve (CV) prosthesis and admitted to the ER for acute coronary syndrome. Coronary angiography revealed the patency of the coronary artery by-pass grafts but was impossible to cannulate the left main "imprisoned" by the CV prosthesis struts. Aortography showed an excessive gap between the CV struts and the coronary ostium. To cross the CV struts, we developed a "proboscis" catheter by cutting away the proximal end of the 7F JL 4 catheter and putting inside the 5F Heartrail catheter...
December 1, 2013: Catheterization and Cardiovascular Interventions
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