keyword
MENU ▼
Read by QxMD icon Read
search

Low complexity

keyword
https://www.readbyqxmd.com/read/28742939/disparate-peroxisome-related-defects-in-arabidopsis-pex6-and-pex26-mutants-link-peroxisomal-retrotranslocation-and-oil-body-utilization
#1
Kim L Gonzalez, Wendell A Fleming, Yun-Ting Kao, Zachary J Wright, Savina V Venkova, Meredith J Ventura, Bonnie Bartel
Catabolism of fatty acids stored in oil bodies is essential for Arabidopsis seed germination and seedling development. This fatty acid breakdown occurs in peroxisomes, organelles that sequester oxidative reactions. Import of peroxisomal enzymes is facilitated by peroxins including PEX5, a receptor that delivers cargo proteins from the cytosol to the peroxisomal matrix. After cargo delivery, a complex of the PEX1 and PEX6 ATPases and the PEX26 tail-anchored membrane protein removes ubiquitinated PEX5 from the peroxisomal membrane...
July 25, 2017: Plant Journal: for Cell and Molecular Biology
https://www.readbyqxmd.com/read/28742853/leadership-and-management-training-as-a-catalyst-to-health-system-strengthening-in-low-income-settings-evidence-from-implementation-of-the-zambia-management-and-leadership-course-for-district-health-managers-in-zambia
#2
Wilbroad Mutale, Anne-Thora Vardoy-Mutale, Arthur Kachemba, Roman Mukendi, Kupela Clarke, Dennis Mulenga
BACKGROUND: Research has shown that the modes of leadership and management may influence health outcomes. However, majority of health leaders and managers in many low-income countries are promoted on account of clinical expertise. It has been recognised that these new managers are often ill-prepared for managing complex health systems. In response to this challenge, the Zambian Ministry of Health (MoH) has developed the Governance and Management Capacity Building (GMCB) Strategic Plan (2012-2016), whose overarching goal is to improve health sector governance and create an environment that is result-oriented, accountable and transparent...
2017: PloS One
https://www.readbyqxmd.com/read/28742733/intravoxel-incoherent-motion-model-free-determination-of-tissue-type-in-abdominal-organs-using-machine-learning
#3
Alexander Ciritsis, Cristina Rossi, Moritz C Wurnig, Valerie Phi Van, Andreas Boss
PURPOSE: For diffusion data sets including low and high b-values, the intravoxel incoherent motion model is commonly applied to characterize tissue. The aim of the present study was to show that machine learning allows a model-free approach to determine tissue type without a priori assumptions on the underlying physiology. MATERIALS AND METHODS: In 8 healthy volunteers, diffusion data sets were acquired using an echo-planar imaging sequence with 16 b-values in the range between 0 and 1000 s/mm...
July 24, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28742350/complexation-behavior-of-polyelectrolytes-and-polyampholytes
#4
Arun Kumar Narayanan Nair, Arturo Martinez Jimenez, Shuyu Sun
We perform grand canonical Monte Carlo simulations to study the pH titrations of isolated polyampholytes and polyelectrolyte-polyampholyte complexes in dilute solutions. Our simulations indicate that the electrostatic interactions promote the coexistence of opposite charges along the polyampholyte chain during titration. The repulsion between excess charges typically dominates the electrostatic interaction and leads to polymer stretching. Salt ions can screen the repulsion between excess charges as well as the fluctuation-induced attraction between opposite charges, and therefore make the variation between titration curves of polyampholytes and the ideal (no electrostatic interactions) curves less significant...
July 25, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28742119/doestrare-a-statistical-test-to-identify-local-enrichments-in-rare-genomic-variants-associated-with-disease
#5
Elodie Persyn, Matilde Karakachoff, Solena Le Scouarnec, Camille Le Clézio, Dominique Campion, French Exome Consortium, Jean-Jacques Schott, Richard Redon, Lise Bellanger, Christian Dina
Next-generation sequencing technologies made it possible to assay the effect of rare variants on complex diseases. As an extension of the "common disease-common variant" paradigm, rare variant studies are necessary to get a more complete insight into the genetic architecture of human traits. Association studies of these rare variations show new challenges in terms of statistical analysis. Due to their low frequency, rare variants must be tested by groups. This approach is then hindered by the fact that an unknown proportion of the variants could be neutral...
2017: PloS One
https://www.readbyqxmd.com/read/28742099/variants-of-acan-are-associated-with-severity-of-lumbar-disc-herniation-in-patients-with-chronic-low-back-pain
#6
Romain Shanil Perera, Poruwalage Harsha Dissanayake, Upul Senarath, Lalith Sirimevan Wijayaratne, Aranjan Lional Karunanayake, Vajira Harshadeva Weerabaddana Dissanayake
INTRODUCTION: Disc herniation is a complex spinal disorder associated with disability and high healthcare cost. Lumbar disc herniation is strongly associated with disc degeneration. Candidate genes of the aggrecan metabolic pathway may associate with the severity of lumbar disc herniation. OBJECTIVES: This study evaluated the association of single nucleotide variants (SNVs) of the candidate genes of the aggrecan metabolic pathway with the severity of lumbar disc herniation in patients with chronic mechanical low back pain...
2017: PloS One
https://www.readbyqxmd.com/read/28742052/a-semi-analytical-model-of-time-reversal-cavity-for-high-amplitude-focused-ultrasound-applications
#7
Justine Robin, Mickael Tanter, Mathieu Pernot
Time reversal cavities (TRC) have been proposed as an efficient approach for 3D ultrasound therapy. They indeed allow precise spatio-temporal focusing of high power ultrasound pulses within a large region of interest with a low number of transducers. Leaky TRCs are usually built by placing a multiple scattering medium such as a random rods forest in a reverberating cavity, and the final peak pressure gain of the device only depends on the temporal length of its impulse response. Such multiple scattering in a reverberating cavity is a complex phenomenon, and the optimization of the device's gain is usually a cumbersome process, mostly empirical, and requiring numerical simulations with extremely long computational times...
July 25, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28742039/reconstructing-interlaced-high-dynamic-range-video-using-joint-learning
#8
Inchang Choi, Seung-Hwan Baek, Min H Kim
For extending the dynamic range of video, it is a common practice to capture multiple frames sequentially with different exposures and combine them to extend the dynamic range of each video frame. However, this approach results in typical ghosting artifacts due to fast and complex motion in nature. As an alternative, video imaging with interlaced exposures has been introduced to extend the dynamic range. However, the interlaced approach has been hindered by jaggy artifacts and sensor noise, leading to concerns over image quality...
July 24, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28742036/study-of-temporal-effects-on-subjective-video-quality-of-experience
#9
Christos G Bampis, Zhi Li, Anush K Moorthy, Ioannis Katsavounidis, Anne Aaron, Alan C Bovik
HTTP adaptive streaming is being increasingly deployed by network content providers such as Netflix and YouTube. By dividing video content into data chunks encoded at different bitrates, a client is able to request the appropriate bitrate for the segment to be played next based on the estimated network conditions. However, this can introduce a number of impairments, including compression artifacts and rebuffering events which can severely impact an end-user's quality of experience (QoE). We have recently created a new video quality database which simulates a typical video streaming application, using long video sequences and interesting Netflix content...
July 20, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28742035/fast-low-rank-shared-dictionary-learning-for-image-classification
#10
Tiep Huu Vu, Vishal Monga
Despite the fact that different objects possess distinct class-specific features, they also usually share common patterns. This observation has been exploited partially in a recently proposed dictionary learning framework by separating the particularity and the commonality (COPAR). Inspired by this, we propose a novel method to explicitly and simultaneously learn a set of common patterns as well as class-specific features for classification with more intuitive constraints. Our dictionary learning framework is hence characterized by both a shared dictionary and particular (class-specific) dictionaries...
July 20, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28741938/new-synthesis-of-nzvi-c-composites-as-an-efficient-adsorbent-for-the-uptake-of-u-vi-from-aqueous-solutions
#11
Haibo Liu, Mengxue Li, Tianhu Chen, Changlun Chen, Njud S Alharbi, Tasawar Hayat, Dong Chen, Qiang Zhang, Yubing Sun
New nanoscale zero-valent iron/carbon (nZVI/C) composites were successfully synthesized by heating natural hematite and pine sawdust at 800 ºC under nitrogen conditions. The characteristic results indicated that as-prepared nZVI/C composites presented the massive reactive sites by SEM, XRD, FT-IR and XPS techniques. No effect of ionic strength revealed that inner-sphere surface complexation dominated uptake of U(VI) on nZVI/C composites. The uptake mechanism of U(VI) on nZVI/C composites was demonstrated to be the simultaneous adsorption and reduction by XPS and XANES techniques...
July 25, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28741908/research-capacity-for-childhood-obesity-prevention-in-latin-america-an-area-for-growth
#12
Diana C Parra, Susan Vorkoper, Harold W Kohl, Benjamin Caballero, Carolina Batis, Alejandra Jauregui, Jessica Mason, Michael Pratt
BACKGROUND: The rise of childhood obesity in Latin America calls for research capacity to understand, monitor and implement strategies, policies and programmes to address it. OBJECTIVE: The objective of the study was to assess current research capacity in Latin America related to childhood obesity, nutrition and physical activity. METHODS: We conducted a search of peer-reviewed articles on childhood obesity in Latin America with at least one Latin American author from 2010 to May 2015...
July 2017: Obesity Reviews: An Official Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28741878/anticancer-gold-n-heterocyclic-carbene-complexes-a-comparative-in-vitro-and-ex-vivo-study
#13
Angela Casini, Natalia Estrada-Ortiz, Chiara Gabbiani, Federica Guarra, Geny Groothuis, Inge de Graaf, Marina de Jager, Lorella Marchetti
A series of organometallic Au(I) N-heterocyclic carbene (NHC) complexes was synthesized and characterized on anticancer activity in four human cancer cell lines. The compounds' toxicity in healthy tissue was determined using precision cut kidney slices (PCKS) as a tool to determine the potential selectivity of the Au complexes ex vivo. All evaluated compounds presented cytotoxic activity towards the cancer cells in the nano- or low micromolar range. The mixed Au(I) NHC complex - (ter-butylethynyl)-1,3-bis-(2,6-diisopropylphenyl)-imidazol-2-ylidene gold(I), bearing an alkynyl moiety as ancillary ligand, showed high cytotoxicity in cancer cells in vitro, while being barely toxic in healthy rat kidney tissues...
July 25, 2017: ChemMedChem
https://www.readbyqxmd.com/read/28741854/toward-activity-origin-of-electrocatalytic-hydrogen-evolution-reaction-on-carbon-rich-crystalline-coordination-polymers
#14
Lihuan Wang, Diana C Tranca, Jian Zhang, Yanpeng Qi, Stavroula Sfaelou, Tao Zhang, Renhao Dong, Xiaodong Zhuang, Zhikun Zheng, Gotthard Seifert
The fundamental understanding of electrocatalytic active sites for hydrogen evolution reaction (HER) is significantly important for the development of metal complex involved carbon electrocatalysts with low kinetic barrier. Here, the MSx Ny (M = Fe, Co, and Ni, x/y are 2/2, 0/4, and 4/0, respectively) active centers are immobilized into ladder-type, highly crystalline coordination polymers as model carbon-rich electrocatalysts for H2 generation in acid solution. The electrocatalytic HER tests reveal that the coordination of metal, sulfur, and nitrogen synergistically facilitates the hydrogen ad-/desorption on MSx Ny catalysts, leading to enhanced HER kinetics...
July 25, 2017: Small
https://www.readbyqxmd.com/read/28741361/3d-printed-shape-memory-objects-based-on-olefin-ionomer-of-zinc-neutralized-poly-ethylene-co-methacrylic-acid
#15
Zhiyang Zhao, Fang Peng, Kevin A Cavicchi, Mukerrem Miko Cakmak, Robert A Weiss, Bryan D Vogt
3D printing enables the net shape manufacturing of objects with minimal material waste and low tooling costs, but the functionality is generally limited by available materials, especially for extrusion based printing such as Fused Deposition Modeling (FDM). Here we demonstrate shape memory behavior of 3D printed objects with FDM using a commercially available olefin ionomer, Surlyn 9520, which is zinc neutralized poly(ethylene-co-methacrylic acid). The initial fixity for 3D printed and compression molded samples was similar, but the initial recovery was much lower for the 3D printed sample (R=58%) than the compression molded sample (R=83%)...
July 25, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28741350/3d-printed-and-microcontrolled-the-one-hundred-dollars-scanning-electrochemical-microscope
#16
Gabriel Negrão Meloni
The design and fabrication of a versatile and low-cost Electrochemical Scanning Probe Microscope (EC-SPM) is presented. The proposed equipment relies on the use of modern prototyping tools such as 3D printers and microcontroller boards and only a few "off-the-shelf" parts to deliver a simple yet powerful EC-SPM equipment capable of performing simple space resolved electrochemical measurements. The equipment was able to perform space resolved electrochemical measurements using a Platinum ultramicroelectrode (UME) as the working electrode on a Scanning Electrochemical Microscope (SECM) configuration and was used to record approach curves, line scans and array scans over an insulating substrate...
July 25, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28741108/automated-clean-up-separation-and-detection-of-polycyclic-aromatic-hydrocarbons-in-particulate-matter-extracts-using-a-2d-lc-2d-gc-system-a-method-translation-from-two-fids-to-two-ms-detectors
#17
Hwanmi Lim, Trifa M Ahmed, Christoffer Bergvall, Roger Westerholm
An online two-dimensional (2D) liquid chromatography/2D gas chromatography system with two mass-selective detectors has been developed on the basis of a previous system with two flame ionization detectors. The method translation involved the change of carrier gas from hydrogen to helium, column dimension and detectors. The 2D system with two mass-selective detectors was validated with use of polycyclic aromatic hydrocarbon (PAH) standards and two standard reference materials from air and diesel exhaust. Furthermore, the system was applied to a real sample, wood smoke particulates...
July 24, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28739800/cell-free-production-of-a-functional-oligomeric-form-of-a-chlamydia-major-outer-membrane-protein-momp-for-vaccine-development
#18
Wei He, Martina Felderman, Angela C Evans, Jia Geng, David Homan, Feliza Bourguet, Nicholas O Fischer, Yuanpei Li, Kit S Lam, Aleksandr Noy, Li Xing, R Holland Cheng, Amy Rasley, Craig D Blanchette, Kurt Kamrud, Nathanial Wang, Heather Gouvis, Todd C Peterson, Bolyn Hubby, Matthew A Coleman
Chlamydia is a prevalent sexually transmitted disease that infects more than 100 million people worldwide. Although most individuals infected with Chlamydia trachomatis are initially asymptomatic, symptoms can arise if left undiagnosed. Long-term infection can result in debilitating conditions such as pelvic inflammatory disease, infertility, and blindness. Chlamydia infection, therefore, constitutes a significant public health threat, underscoring the need for a Chlamydia-specific vaccine. Chlamydia strains express a major outer-membrane protein (MOMP) that has been shown to be an effective vaccine antigen...
July 24, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28739778/a-multilevel-analysis-of-risk-and-protective-factors-for-canadian-youth-injured-or-killed-by-interpersonal-violence
#19
Carolyn E Snider, Marni Brownell, Brenden Dufault, Nicole Barrett, Heather Prior, Carla Cochrane
PURPOSE: The study's purpose was to determine individual-level and neighbourhood-level risk and protective factors for severe intentional injury among youth. METHODS: We conducted a multilevel case-control study using registry data to determine individual-level and neighbourhood-level social determinants associated with severe violent injury/homicide among youth from Winnipeg, Manitoba. RESULTS: The study includes 13 206 youth, aged 12-24 years (1222 cases, 11 984 controls)...
July 24, 2017: Injury Prevention: Journal of the International Society for Child and Adolescent Injury Prevention
https://www.readbyqxmd.com/read/28739544/in-vitro-degradation-of-calcium-phosphates-effect-of-multiscale-porosity-textural-properties-and-composition
#20
A Díez-Escudero, M Espanol, S Beats, M P Ginebra
The capacity of calcium phosphates to be replaced by bone is tightly linked to their resorbability. However, the relative importance of some textural parameters on their degradation behaviour is still unclear. The present study aims to quantify the effect of composition, specific surface area (SSA), and porosity at various length scales (nano-, micro- and macroporosity) on the in vitro degradation of different calcium phosphates. Degradation studies were performed in an acidic medium to mimic the osteoclastic environment...
July 21, 2017: Acta Biomaterialia
keyword
keyword
71592
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"