Nebal S Abu Hussein, Stephanie Giezendanner, Pascal Urwyler, Pierre-Olivier Bridevaux, Prashant N Chhajed, Thomas Geiser, Ladina Joos Zellweger, Malcolm Kohler, David Miedinger, Zahra Pasha, Robert Thurnheer, Christophe von Garnier, Joerg D Leuppi
BACKGROUND: Patients with chronic obstructive pulmonary disease (COPD) often suffer from acute exacerbations. Our objective was to describe recurrent exacerbations in a GP-based Swiss COPD cohort and develop a statistical model for predicting exacerbation. METHODS: COPD cohort demographic and medical data were recorded for 24 months, by means of a questionnaire-based COPD cohort. The data were split into training (75%) and validation (25%) datasets. A negative binomial regression model was developed using the training dataset to predict the exacerbation rate within 1 year...
October 23, 2023: Journal of Clinical Medicine