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Right ventricle assessment

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https://www.readbyqxmd.com/read/29344379/changes-in-contractile-protein-expression-are-linked-to-ventricular-stiffness-in-infants-with-pulmonary-hypertension-or-right-ventricular-hypertrophy-due-to-congenital-heart-disease
#1
Andrew R Bond, Dominga Iacobazzi, Safa Abdul-Ghani, Mohammed Ghorbel, Kate Heesom, Mariangela Wilson, Christopher Gillett, Sarah J George, Massimo Caputo, Saadeh Suleiman, Robert M R Tulloh
Background: The right ventricle (RV) is not designed to sustain high pressure leading to failure. There are no current medications to help RV contraction, so further information is required on adaption of the RV to such hypertension. Methods: The Right Ventricle in Children (RVENCH) study assessed infants with congenital heart disease undergoing cardiac surgery with hypertensive RV. Clinical and echocardiographic data were recorded, and samples of RV were taken from matched infants, analysed for proteomics and compared between pathologies and with clinical and echocardiographic outcome data...
2018: Open Heart
https://www.readbyqxmd.com/read/29343014/-correlation-between-peripheral-venous-oxygen-saturation-and-hemodynamic-parameters-in-patients-with-pulmonary-hypertension
#2
C Hong, J Y Li, R K Chen, C L Liu, X N Wang, S M Qing, X F Su, N F Zhang
Objective: To investigate the correlation of peripheral venous oxygen saturation (SpvO(2)) with mixed venous oxygen saturation (SvO(2)), pulmonary vascular resistance (PVR) and cardiac index (CI) in patients with pulmonary hypertension (PH), in order to predict these parameters using SpvO(2) and assess the prognosis of patients. Methods: Hospitalized patients diagnosed with PH by right heart catheterization in the Guangzhou Institute of Respiratory Diseases from July 2015 to October 2016 were retrospectively analyzed...
January 12, 2018: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/29340081/pcpa-protects-against-monocrotaline-induced-pulmonary-arterial-remodeling-in-rats-potential-roles-of-connective-tissue-growth-factor
#3
Yang Bai, Zhong-Xia Li, Yue-Tong Zhao, Mo Liu, Yun Wang, Guo-Chao Lian, Qi Zhao, Huai-Liang Wang
The purpose of this study was to investigate the mechanism of monocrotaline (MCT)-induced pulmonary artery hypertension (PAH) and determine whether 4-chloro-DL-phenylalanine (PCPA) could inhibit pulmonary arterial remodeling associated with connective tissue growth factor (CTGF) expression and downstream signal pathway. MCT was administered to forty Sprague Dawley rats to establish the PAH model. PCPA was administered at doses of 50 and 100 mg/kg once daily for 3 weeks via intraperitoneal injection. On day 22, the pulmonary arterial pressure (PAP), right ventricle hypertrophy index (RVI) and pulmonary artery morphology were assessed and the serotonin receptor-1B (SR-1B), CTGF, p-ERK/ERK were measured by western blot or immunohistochemistry...
December 19, 2017: Oncotarget
https://www.readbyqxmd.com/read/29336370/differences-of-matrix-metalloproteinase-2-expression-between-left-and-right-ventricles-in-response-to-nandrolone-decanoate-and-or-swimming-training-in-mice
#4
Ying Bai, Xu-Bo Shi, Yu-Qiong Zhang, Yue-Li Wang, Xin-Yao Liu, María Asunción Esteve-Pastor
BACKGROUND: Matrix metalloproteinase (MMP)-2 plays an important role in the remodeling of left ventricles (LVs) and right ventricles (RVs). We investigated the differences of MMP-2 expression between LV and RV in response to nandrolone decanoate (ND), swimming training (ST), and combined ND and ST (NS) in mice, based on their structural, functional, and biochemical characteristics. METHODS: Totally 28 male C57B1 mice (6 weeks old; 20-23 g) were divided into four groups, including the control (n = 7), ND (n = 6), ST (n = 8), and NS (n = 7) groups...
January 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29327650/transesophageal-echocardiography-use-in-diagnosis-and-management-of-embolized-intravascular-foreign-bodies
#5
James Taylor Herbert, Miklos David Kertai
The increasing use of endovascular interventions coupled with the large number of published case series detailing complications attest to the likelihood that anesthesiologists will encounter a case of intravascular foreign body embolization during their careers. Transesophageal echocardiography is essential to the diagnosis and management of traumatic and intravascular foreign bodies embolized to the heart because it can identify not only the foreign body but also hemodynamically significant lesions to radiolucent anatomic structures prior to and during surgical exploration...
October 1, 2017: Seminars in Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29320957/cardiovascular-and-metabolic-health-of-74-children-from-women-previously-diagnosed-with-polycystic-ovary-syndrome-in-comparison-with-a-population-based-reference-cohort
#6
Marlieke A de Wilde, Jacobien B Eising, Marlise N Gunning, Maria P H Koster, Annemieke M V Evelein, Geertje W Dalmeijer, Cuno S P M Uiterwaal, Marinus J C Eijkemans, Cornelis K van der Ent, Folkert J Meijboom, Bart C J M Fauser
Women with polycystic ovary syndrome (PCOS) have compromised cardiovascular health profiles and an increased risk of pregnancy complications. In order to evaluate potential consequences, we aim to compare the cardiovascular and metabolic health of the children from women with PCOS with a population-based reference cohort. We included children from women with PCOS between the age of 2.5 to 4 years (n = 42) and 6 to 8 years (n = 32). The reference groups consisted of 168 (3-4 years old) and 130 children (7-8 years old)...
January 1, 2018: Reproductive Sciences
https://www.readbyqxmd.com/read/29312737/perforation-of-myocardial-wall-and-great-vessels-after-cardiovascular-interventions-a-5-year-analysis
#7
Zdenek Provaznik, Andreas Holzamer, Daniele Camboni, Leopold Rupprecht, Markus Resch, Sigrid Wittmann, Christof Schmid, Bernhard Floerchinger
Background: Less invasive procedures have replaced open surgical treatment in many cardiovascular disorders. During these interventions, iatrogenic cardiac perforation may ensue, which is a severe complication and requires immediate diagnostic assessment and treatment. Methods: From March 2011 to April 2016, all patients referred to the Dept. of Cardio-thoracic Surgery with the diagnosis of iatrogenic perforation of myocardial wall or great vessels were included into the retrospective study...
December 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29305036/right-ventricular-structure-and-function-in-the-veteran-ultramarathon-runner-is-there-evidence-for-chronic-maladaptation
#8
Oliver Rothwell, Keith George, John Somauroo, Rachel Lord, Mike Stembridge, Rob Shave, Martin D Hoffman, Mathew Wilson, Euan Ashley, Francois Haddad, Thijs M H Eijsvogels, David Oxborough
BACKGROUND: It has been proposed that chronic exposure to prolonged strenuous exercise may result in maladaptation of the right ventricle (RV). The of this study aim was to establish RV structure and function, including septal insertion points, using conventional echocardiography and myocardial strain (ε) imaging in a veteran population of ultramarathon runners (UR) and age- and sex-matched controls. METHODS: A retrospective study design provided 40 UR (>35 years old; mean ± SD training experience, 18 ± 12 years) and 24 sedentary controls who had previously undergone conventional two-dimensional, tissue Doppler and speckle-tracking echocardiography to measure RV size and function...
January 3, 2018: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/29299780/the-key-roles-of-negative-pressure-breathing-and-exercise-in-the-development-of-interstitial-pulmonary-edema-in-professional-male-scuba-divers
#9
Olivier Castagna, Jacques Regnard, Emmanuel Gempp, Pierre Louge, François Xavier Brocq, Bruno Schmid, Anne-Virginie Desruelle, Valentin Crunel, Adrien Maurin, Romain Chopard, David Hunter MacIver
BACKGROUND: Immersion pulmonary edema is potentially a catastrophic condition; however, the pathophysiological mechanisms are ill-defined. This study assessed the individual and combined effects of exertion and negative pressure breathing on the cardiovascular system during the development of pulmonary edema in SCUBA divers. METHODS: Sixteen male professional SCUBA divers performed four SCUBA dives in a freshwater pool at 1 m depth while breathing air at either a positive or negative pressure both at rest or with exercise...
January 3, 2018: Sports Medicine—Open
https://www.readbyqxmd.com/read/29298962/-echocardiographic-evaluation-in-the-course-of-hypertension-in-the-elderly
#10
Monika Rynkowska-Kidawa, Michał Kidawa, Joanna Kapusta, Robert Irzmański, Jan Kowalski
Factor contributing to the high prevalence of hypertension in the elderly is currently observed high survival rate of people diagnosed and treated hypertension, as well as the aging process itself. Detection of systemic complications was considered to be an important element of the diagnosis of hypertension as well as an important parameter of prognosis. Nowadays, echocardiography is the main tool used to assess heart cavities and to diagnose ventricular hypertrophy. AIM: The aim of the study was echocardiographic evaluation of the heart in the course of hypertension in the elderly...
December 22, 2017: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29287139/fetal-interventions-for-structural-heart-disease
#11
David N Schidlow, Lindsay Freud, Kevin Friedman, Wayne Tworetzky
Fetal cardiac intervention (FCI) offers the potential to alter in utero anatomy and physiology. For aortic stenosis with evolving hypoplastic left heart syndrome and pulmonary atresia with intact ventricular septum with evolving hypoplastic right heart syndrome, FCI may result in maintenance of a biventricular circulation, thus avoiding single-ventricle palliation and its attendant complications. In the case of hypoplastic left heart syndrome with intact atrial septum, FCI may ameliorate in utero pathophysiology and portend a more favorable postnatal prognosis...
December 2017: Echocardiography
https://www.readbyqxmd.com/read/29286273/the-2017-seventh-world-congress-of-pediatric-cardiology-cardiac-surgery-week-in-review-imaging
#12
Elif S Selamet Tierney
The Imaging Program at the 7th World Congress highlighted the versatility and diagnostic power of the current and upcoming imaging tools in Pediatric Cardiology and Cardiac Surgery. Several experts presented interesting as well as practical data on the use of 2D and 3D Echocardiography, magnetic resonance imaging and computed tomography in the fetus, child, and adult with congenital heart disease. Bridging sessions coupled use of these imaging modalities and screening practices in patients with acquired heart disease...
December 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/29285347/patient-specific-simulations-for-planning-treatment-in-congenital-heart-disease
#13
Claudio Capelli, Emilie Sauvage, Giuliano Giusti, Giorgia M Bosi, Hopewell Ntsinjana, Mario Carminati, Graham Derrick, Jan Marek, Sachin Khambadkone, Andrew M Taylor, Silvia Schievano
Patient-specific computational models have been extensively developed over the last decades and applied to investigate a wide range of cardiovascular problems. However, translation of these technologies into clinical applications, such as planning of medical procedures, has been limited to a few single case reports. Hence, the use of patient-specific models is still far from becoming a standard of care in clinical practice. The aim of this study is to describe our experience with a modelling framework that allows patient-specific simulations to be used for prediction of clinical outcomes...
February 6, 2018: Interface Focus
https://www.readbyqxmd.com/read/29280176/-y-sign-at-the-level-of-the-3-vessel-and-trachea-view-an-effective-fetal-marker-of-aortic-dextroposition-anomalies-in-the-first-trimester
#14
Marcin Pasternok, Agnieszka Nocun, Anna Knafel, Mariusz Grzesiak, Maciej Orzechowski, Katarzyna Konarska, Artur Ludwin, Inga Ludwin, Piotr Zymroz, Anna Parzynska, Marcin Wiechec
OBJECTIVES: The "Y sign" at the level of the 3-vessel and trachea view corresponds to thinning of main pulmonary artery and arterial duct and a dilated transverse aortic arch. The purpose of this study was to evaluate the Y sign for the diagnosis of aortic dextroposition anomalies at the time of the first-trimester scan and to assess the screening performance of only the Y sign, only abnormal left axis deviation (axis sign), and their combination for the diagnosis of aortic dextroposition anomalies...
December 27, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29273239/percutaneous-pulmonary-valve-implantation-in-small-conduits-a-multicenter-experience
#15
Sebastien Hascoet, José Diogo Martins, Haysam Baho, Saule Kadirova, Fatima Pinto, Florent Paoli, Fadi Bitar, Abdelfatah Abu Haweleh, Anselm Uebing, Philippe Acar, Olivier Ghez, Alain Fraisse
BACKGROUND: Guidelines allow percutaneous pulmonary valve implantation (PPVI) in conduits above 16mm diameter. Balloon dilatation of a conduit to a diameter>110% of the original implant size is also not recommended. We analyzed patients undergoing PPVI in such conditions. METHODS AND RESULTS: Nine patients (May 2008-July 2016) from 8 institutions underwent PPVI in conduits <16mm diameter. Five patients with 16-18mm conduit diameter underwent PPVI after over-expansion of the conduit>110%...
December 5, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29260587/right-ventricular-longitudinal-strain-a-tool-for-diagnosis-and-prognosis-in-light-chain-amyloidosis
#16
Charles Uzan, Olivier Lairez, Pascale Raud-Raynier, Rodrigue Garcia, Bruno Degand, Luc P Christiaens, Michaela B Rehman
OBJECTIVES: Light-chain (AL) amyloidosis can lead to an infiltrative cardiomyopathy with increased wall thickness (IWT) of very poor prognosis. Our primary aim was to analyse the right ventricle (RV) in patients with IWT to discriminate AL amyloidosis from IWT due to hypertrophic cardiomyopathy (HCM) or to arterial hypertension (HTN). Our secondary aim was to assess if RV dysfunction predicts overall mortality in cardiac AL amyloidosis. METHODS: We retrospectively and consecutively compared clinical, biological and echocardiographic data of 315 patients with IWT: 105 biopsy-proven AL amyloidosis patients, 105 patients with HCM and 105 patients with HTN...
December 20, 2017: Amyloid: the International Journal of Experimental and Clinical Investigation
https://www.readbyqxmd.com/read/29249493/exendin-4-improves-cardiovascular-function-and-survival-in-flow-induced-pulmonary-hypertension
#17
Jun-Neng Roan, Chih-Hsin Hsu, Shih-Yuan Fang, Hung-Wen Tsai, Chwan-Yau Luo, Chien-Chi Huang, Chen-Fuh Lam
OBJECTIVES: Systemic left-to-right shunting causes pulmonary arteriopathy, leading to progressive cardiopulmonary failure and a poor prognosis. In this study, we examined the extraglycemic effect of a synthetic glucagon-like peptide, exendin-4, on pulmonary arteriopathy regression and cardiopulmonary function in nondiabetic rats. METHODS: Pulmonary hypertension (PH) was induced by monocrotaline (60 mg/kg, subcutaneous) injection followed by the creation of an aortocaval fistula...
November 7, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29246514/atrial-enlargement-in-the-athlete-s-heart-assessment-of-atrial-function-may-help-distinguish-adaptive-from-pathologic-remodeling
#18
REVIEW
Flavio D'Ascenzi, Francesca Anselmi, Marta Focardi, Sergio Mondillo
Intensive training is associated with hemodynamic changes that typically induce an enlargement of cardiac chambers, involving not only the ventricles but also the atria. The hearts of competitive athletes are characterized by increases in left and right atrial dimensions that have been interpreted as a physiologic adaptation to training. Conversely, some authors have hypothesized maladaptive remodeling; furthermore, the extent of left atrial dimensional remodeling may overlap atrial dilation observed in patients with cardiac disease, representing a challenge for clinicians...
December 12, 2017: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/29246511/fetal-cardiac-function-in-maternal-diabetes-a%C3%A2-conventional-and-speckle-tracking-echocardiographic-study
#19
Joana O Miranda, Rui J Cerqueira, Carla Ramalho, José Carlos Areias, Tiago Henriques-Coelho
BACKGROUND: Intrauterine exposure to a diabetic environment is associated with adverse fetal myocardial remodeling. The aim of this study was to assess the biventricular systolic and diastolic function of fetuses exposed to maternal diabetes (MD) compared with control subjects, using a comprehensive cardiac functional assessment and exploring the role of speckle-tracking to assess myocardial deformation. The authors hypothesized that fetuses exposed to MD present signs of biventricular dysfunction, which can be detected by deformation analysis...
December 12, 2017: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/29245337/assessment-of-pulmonary-arterial-enhancement-on-ct-pulmonary-angiography-using-a-leg-vein-for-contrast-media-administration
#20
Cherry Kim, Choong Wook Lee, Gil-Sun Hong, Gihong Kim, Ki Yeol Lee, Sung-Soo Kim
The purpose of our study was to compare pulmonary artery (PA) enhancement according to venous routes of contrast media (CM) administration in patients who underwent CT pulmonary angiography (CTPA) in the emergency department (ED).This retrospective study reviewed the CTPAs of 24 patients who administered CM via leg veins (group A) and 72 patients via arm veins (group B) with age and gender matching at a ratio of 1:3. Clinical data, aorta attenuation (Aoatten), and PA attenuation (PAatten) were compared between group A and B...
December 2017: Medicine (Baltimore)
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